Herbal Arnica may have a therapeutic and substantial effect in reduced progression and treatment of edema, some scientists suggested.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries in the treatment of strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of the skin, tissues, organs, etc.
Edema is a condition, characterized by excessive accumulation of fluids in some tissues within the body.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the study to compare the efficacy of herbal Arnica and corticosteroids in reduced postoperative edema and bruising associated with rhinoplasty of 48 primary rhinoplasty patients randomized assigned to three groups as follow
* Group P received 10 mg of dexamethasone (intravenously) intraoperatively followed by a 6-day oral tapering dose of methyl-prednisone
* Group A received Arnica three times a day for 4 days, and
* Group C received neither agent and served as the control.
With 3 blinded panelists rated the extent of ecchymosis, the intensity of the ecchymosis, and the severity of the edema
After observing the study over the entire period, scientists postulated that
* There were no significant differences in all groups on the day 2 of postoperative
* In compared to increased swelling of the control group, both groups A and P demonstrated a significant improvement in edema rating.
Interestingly, the conventional medicine administration group exerted a higher intensity of ecchymosis compared to groups A and C on the day of postoperative and all groups displayed no difference in magnitude of edema.
However, between the period of days 2 and 8, groups A and C exhibited significantly more resolution of ecchymosis compared to group P.
The results suggested that although herbal Arnica may have a therapeutic property in reducing edema during the early postoperative period, the herbal medicine did not provide similar benefits in regard to the extent and intensity of ecchymosis in compared to corticosteroids.
In order to further confirmation of the effect of herbal Arnica in reduced postoperative ecchymosis and edema, researchers at the joint study lead University of Miami Miller School of Medicine, conducted an investigation in a select population of healthy volunteers after oculofacial surgery by examining the postoperative course and medical records of a total of 27 patients (16 females, 11 males) with age range was 18 to 70 years using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
According to the result of the experiment, the application of Arnica 50 M (10) 50% and Ledum 50 M (10) pads bilaterally after surgery through postoperative day 6, showed a significantly accelerated healing from day 7 to day 12 in dose depending manner, without inflicting any adverse effects.
The findings suggested that the application of composited Arnica and Ledum displays a potential efficacy in reducing postoperative ecchymosis and edema after oculofacial surgery.
The above differentiation of herbal Arnica in improved edema after surgery were supported by the joint study lead by the Research Center of University of adult male Wistar rats inoculated with 1% carrageenan into the footpad to induce edema then treated with Arnica montana 6cH, dexamethasone (4.0 mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation.
According to the investigation, the application of the Arnica group exhibited anti-edema through increased lymphatic edema absorption, particularly, in late edema presented less intense edema treatment group after adjusting to the individually qualitative of inflammatory vascular events.
Moreover, the edema inhibition of Arnica was attributed to significant reduced mast cell degranulation and increased lymphatic vessel diameter and decreased the production of prostaglandins associated with the development of edema, caused by subcutaneous carrageenan injection in the induction of local inflammation.
Taken together, herbal Arnica may be considered as a functional food in reduced progression and for treatment of edema and ecchymosis.
For More information about yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) A randomized, controlled comparison between arnica and steroids in the management of postrhinoplasty ecchymosis and edema by Totonchi A1, Guyuron B.(PubMed)
(2) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(3) Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation Ana Paula Kawakami,1 Cesar Sato,1 Thayna Neves Cardoso,1 and Leoni Villano Bonamin(Hidawi)
Tuesday, November 5, 2019
Herbal Arctostaphylos uva-ursi, the Free Radicals Scavenger Functional Herb
Herbal Arctostaphylos uva-ursi may have a potential effect in reducing the risk and treatment of oxidative stress-related diseases, some studies suggested.
Oxidative stress is a production of the imbalance of the ratio of free radicals and antioxidants in the bost body.
The imbalance of the ratio of free radicals and antioxidant in the bost body can be caused either by the overproduction of free radicals or antioxidant enzymes are suppressed by the outside sources.
However, most outside sources that suppress the levels of antioxidant enzymes also play an important role in stimulating the overexpression of free radicals, such as chemical toxins
Free radicals are unstable atoms with the unpaired electron in the outer ring. Therefore, in order for them to become stable, free radical either donates or steals an electron from stable molecules, leading to a chain of reaction that facilitates the onset of oxidative stress.
The chain once starts, it can not stop until the electron on the outer ring is paired or inhibited by antioxidant.
Free radical has been known to cause oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospholipids, DNA and RNA.
Antioxidants are stable molecules found abundantly in fruits, vegetables, and herbal medicine.
If oxidative stress-related diseases are associated with the overproduction of free radicals, then long-term intake of a healthy diet high in fruits, vegetables and less in red meat and saturated and trans fat and processed foods can reduce the risk of the diseases in the healthy individuals.
Dr. Halliwell B, in the study to reaffirm the effect of healthy dietary patterns against the onset of oxidative stress said, " diet-derived antioxidants may be particularly important in protecting against these diseases" and
"The physiological relevance of these effects is uncertain, as is the optimal intake of most diet-derived antioxidants. In principle, these questions could be addressed by examining the effects of dietary composition and/or antioxidant supplementation upon parameters of oxidative damage in vivo".
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.
The herbal plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
In the examining the Dr. Bol'shakova IV, the lead author at the Emanuel Institute of Biochemical Physics claim, that Arctostaphylos uva.processes a significant antioxidant property in the inhibition of free radicals generation, researchers launched an investigation to evaluate the concentration of compound that inhibited cell growth by 50% (IC(50)) of a range of phytochemicals and plant extracts.
All selected extracts were differentiated according to the antioxidant and genoprotective effects under conditions of oxidative stress in U937 cells.
Two phytochemicals-resveratrol and citroflavan-3-ol isolated from the herbal Arctostaphylos uva-ursi demonstrated the highest IC50 value of 13.7 microg/mL, compared to the lowest at 9,400 microg/mL. of Echinacea.
Extract of herbal Arctostaphylos uva-ursi displayed a significant attenuation of the oxidative stress induced by the etoposide injection by inhibiting the expression of H2O2- and tBOOH-induced DNA damage.
These results reconfirmed the findings of Dr. Bol'shakova IV team that herbal Arctostaphylos uva-ursi as a non-nutrient dietary constituent may act as significant bioactive compounds in enhancing the antioxidants activity and stimulating the production of antioxidant enzymes if the herb is administrated in an animal model.
Moreover, Dr.Matsuda H the antioxidant team leader at the Kinki University, Osaka in the finding the natural compounds or whole food with potential antioxidant effects evaluated the inhibitory effect of 50% ethanol extracts obtained from the leaves of six Arctostaphylos plants (A. patula, A. viscida, A. canescens, A. Columbiana, A. nevadensis and A. uva-ursi) (Ericaceae).
Injection of the extracts of A. patula showed potent inhibition against tyrosinase, the enzyme that causes oxidation of the skin pigment.
Also, Arctostaphylos uva-ursi not only inhibited the production of melanin from dopachrome by autoxidation and but reduced the over exhibited SOD (superoxide dismutase, free radical)-like activity.
Additionally, Arctostaphylos uva-ursi processed a moderate absorbance in the UV-B area.
The results not only reaffirm the claim of Dr. Bol'shakova IV suggestion but also introduce a new herbal whitening medicine for the skin.
Taken all together, Herbal Arctostaphylos uva-ursi may be considered a functional food for the prevention and an adjunct therapy combine with primary medicine for the treatment of oxidative-related diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Antioxidant properties of plant extracts].[Article in Russian] by Bol'shakova IV, Lozovskaia EL, Sapezhinskiĭ II. (PubMed)
(2) Modulatory effects of resveratrol, citroflavan-3-ol, and plant-derived extracts on oxidative stress in U937 cells by O'Brien NM, Carpenter R, O'Callaghan YC, O'Grady MN, Kerry JP. (PubMed)
(3) Studies of cuticle drugs from natural sources. IV. Inhibitory effects of some Arctostaphylos plants on melanin biosynthesis. by Matsuda H, Higashino M, Nakai Y, Iinuma M, Kubo M, Lang FA. (PubMed)
Oxidative stress is a production of the imbalance of the ratio of free radicals and antioxidants in the bost body.
The imbalance of the ratio of free radicals and antioxidant in the bost body can be caused either by the overproduction of free radicals or antioxidant enzymes are suppressed by the outside sources.
However, most outside sources that suppress the levels of antioxidant enzymes also play an important role in stimulating the overexpression of free radicals, such as chemical toxins
Free radicals are unstable atoms with the unpaired electron in the outer ring. Therefore, in order for them to become stable, free radical either donates or steals an electron from stable molecules, leading to a chain of reaction that facilitates the onset of oxidative stress.
The chain once starts, it can not stop until the electron on the outer ring is paired or inhibited by antioxidant.
Free radical has been known to cause oxidative damage to the enzymes, other protein, unsaturated fatty acid, phospholipids, DNA and RNA.
Antioxidants are stable molecules found abundantly in fruits, vegetables, and herbal medicine.
If oxidative stress-related diseases are associated with the overproduction of free radicals, then long-term intake of a healthy diet high in fruits, vegetables and less in red meat and saturated and trans fat and processed foods can reduce the risk of the diseases in the healthy individuals.
Dr. Halliwell B, in the study to reaffirm the effect of healthy dietary patterns against the onset of oxidative stress said, " diet-derived antioxidants may be particularly important in protecting against these diseases" and
"The physiological relevance of these effects is uncertain, as is the optimal intake of most diet-derived antioxidants. In principle, these questions could be addressed by examining the effects of dietary composition and/or antioxidant supplementation upon parameters of oxidative damage in vivo".
Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to northern North America, Asia, and Europe.
The herb has been used in traditional medicine as a diuretic agent and to treat urinary problems, including bladder infections, kidney infection, kidney stones, pelvic pain, etc.
The herbal plant contains arbutin, ursolic acid, tannic acid, gallic acid, some essential oil and resin, hydroquinones tannins, phenolic glycosides, and flavonoids.
In the examining the Dr. Bol'shakova IV, the lead author at the Emanuel Institute of Biochemical Physics claim, that Arctostaphylos uva.processes a significant antioxidant property in the inhibition of free radicals generation, researchers launched an investigation to evaluate the concentration of compound that inhibited cell growth by 50% (IC(50)) of a range of phytochemicals and plant extracts.
All selected extracts were differentiated according to the antioxidant and genoprotective effects under conditions of oxidative stress in U937 cells.
Two phytochemicals-resveratrol and citroflavan-3-ol isolated from the herbal Arctostaphylos uva-ursi demonstrated the highest IC50 value of 13.7 microg/mL, compared to the lowest at 9,400 microg/mL. of Echinacea.
Extract of herbal Arctostaphylos uva-ursi displayed a significant attenuation of the oxidative stress induced by the etoposide injection by inhibiting the expression of H2O2- and tBOOH-induced DNA damage.
These results reconfirmed the findings of Dr. Bol'shakova IV team that herbal Arctostaphylos uva-ursi as a non-nutrient dietary constituent may act as significant bioactive compounds in enhancing the antioxidants activity and stimulating the production of antioxidant enzymes if the herb is administrated in an animal model.
Moreover, Dr.Matsuda H the antioxidant team leader at the Kinki University, Osaka in the finding the natural compounds or whole food with potential antioxidant effects evaluated the inhibitory effect of 50% ethanol extracts obtained from the leaves of six Arctostaphylos plants (A. patula, A. viscida, A. canescens, A. Columbiana, A. nevadensis and A. uva-ursi) (Ericaceae).
Injection of the extracts of A. patula showed potent inhibition against tyrosinase, the enzyme that causes oxidation of the skin pigment.
Also, Arctostaphylos uva-ursi not only inhibited the production of melanin from dopachrome by autoxidation and but reduced the over exhibited SOD (superoxide dismutase, free radical)-like activity.
Additionally, Arctostaphylos uva-ursi processed a moderate absorbance in the UV-B area.
The results not only reaffirm the claim of Dr. Bol'shakova IV suggestion but also introduce a new herbal whitening medicine for the skin.
Taken all together, Herbal Arctostaphylos uva-ursi may be considered a functional food for the prevention and an adjunct therapy combine with primary medicine for the treatment of oxidative-related diseases.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Antioxidant properties of plant extracts].[Article in Russian] by Bol'shakova IV, Lozovskaia EL, Sapezhinskiĭ II. (PubMed)
(2) Modulatory effects of resveratrol, citroflavan-3-ol, and plant-derived extracts on oxidative stress in U937 cells by O'Brien NM, Carpenter R, O'Callaghan YC, O'Grady MN, Kerry JP. (PubMed)
(3) Studies of cuticle drugs from natural sources. IV. Inhibitory effects of some Arctostaphylos plants on melanin biosynthesis. by Matsuda H, Higashino M, Nakai Y, Iinuma M, Kubo M, Lang FA. (PubMed)
Artichoke Inhibits Hepatitis C Virus Against Liver Infection
Scientists may have found a natural remedy for the treatment of hepatitis C infection with no side effects, according to studies.
Hepatitis C infection is an inflammatory liver disease associated with viral hepatitis C. The viral infection has affected over a million Americans today according to the statistic.
Epidemiological studies suggested that persistent infection with the hepatitis C virus (HCV) is a major risk for the development of HCC, the fifth most common cancer, and the third most common cause for cancer death in the world.
Contaminated blood and fluids are the most common causes of hepatitis C virus (HCV) infection.
Hepatitis C induces liver cancer through many stages including
* The incubation period which lasts about 45 days after exposing to the virus.
* Acute hepatitis, the short-term illness may last about 6 months. Most people can get rid of the virus in this stage, particularly to those with the strong immune system.
* Chronic hepatitis C if you can not get rid of the virus in the acute stage, the immune system will adapt to the new change, leading to chronic liver inflammation by the hep C virus.
* Cirrhosis, the liver scar, normally is formed due to the progression of the inflammation. Cirrhosis can be developed over a period of 20 years, after initial exposure to the virus.
* Liver cancer, the death of liver cells due to overexpression of liver scars.
Dr. Gremion C, the lead scientist in the attempt to explain the risk hepatitis C and immune system, said, "While a persistent infection is generally associated with a weak CD4+ and CD8+ T cell response during the acute phase, there is no good explanation as to why this response is strong enough in 20% of acutely infected people such that they spontaneously resolve the infection".
The results strongly suggested that if you have a strong immune system, your risk of hepatitis C infection can be resolved naturally.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding a natural ingredient for the treatment of hepatitis C which presently affects millions of people globally examined the traditional use of Egyptian artichoke (WEA) for the treatment of HCV-infection and complications.
Injection of water extract of a WEA plant decreased the HCV viral load below the detection level in 12 out of 15 patients. In other words, artichoke exerted strong anti-HCV infection, depending on the state of the severity of the disease.
Furthermore, the water extract normalized the levels of enzymes associated with liver function and damage.
Moreover, The total WEA extract at IC50 ∼ 20 μg ml(-1), inhibited abnormal expression of genes in patients with hepatitis C infection, involving in drug metabolism and synthesis of cholesterol, steroids, and other lipids (CYP2B6 (OH-BUP)) and the formation and breakdown (metabolism) of various molecules and chemicals within cells (CYP2C19 (5-OH-OME)).
WEA was found to be more effective in inhibiting hepatitis C infection compared to the Hepar SL Forte(®) due to the presence of sesquiterpenes versus the abundance of phenolic compounds of the Hepar SL Forte(®).
In chemicals analysis, grosheimol and cynaropicrin, isolated from the WEA showed the most inhibitory effect against HCV with half-maximal effective concentrations (EC50s) in the low micromolar range.
Both tested compounds inhibited HCV entry into target cells in both cell-free infections and cell-cell transmission.
Both compounds belong to the group of sesquiterpene lactones which are found in the WEA but not in the Hepar SL Forte(®).
The results clearly supported the use of WEA in traditional use for the treatment of liver viral infection and complications.
Taken altogether, herbal Artichoke may be considered a functional remedy for the prevention and treatment of HCV infection, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials by Elsebai MF1, Abass K2, Hakkola J3, Atawia AR4, Farag MA. (PubMed)
(2) Pan-genotypic Hepatitis C Virus Inhibition by Natural Products Derived from the Wild Egyptian Artichoke by Elsebai MF1, Koutsoudakis G2, Saludes V2, Pérez-Vilaró G2, Turpeinen A3, Mattila S3, Pirttilä AM4, Fontaine-Vive F5, Mehiri M5, Meyerhans A6, Diez. (PubMed)
(3) Hepatitis C virus and the immune system: a concise review by Gremion C1, Cerny A. (PubMed)
Hepatitis C infection is an inflammatory liver disease associated with viral hepatitis C. The viral infection has affected over a million Americans today according to the statistic.
Epidemiological studies suggested that persistent infection with the hepatitis C virus (HCV) is a major risk for the development of HCC, the fifth most common cancer, and the third most common cause for cancer death in the world.
Contaminated blood and fluids are the most common causes of hepatitis C virus (HCV) infection.
Hepatitis C induces liver cancer through many stages including
* The incubation period which lasts about 45 days after exposing to the virus.
* Acute hepatitis, the short-term illness may last about 6 months. Most people can get rid of the virus in this stage, particularly to those with the strong immune system.
* Chronic hepatitis C if you can not get rid of the virus in the acute stage, the immune system will adapt to the new change, leading to chronic liver inflammation by the hep C virus.
* Cirrhosis, the liver scar, normally is formed due to the progression of the inflammation. Cirrhosis can be developed over a period of 20 years, after initial exposure to the virus.
* Liver cancer, the death of liver cells due to overexpression of liver scars.
Dr. Gremion C, the lead scientist in the attempt to explain the risk hepatitis C and immune system, said, "While a persistent infection is generally associated with a weak CD4+ and CD8+ T cell response during the acute phase, there is no good explanation as to why this response is strong enough in 20% of acutely infected people such that they spontaneously resolve the infection".
The results strongly suggested that if you have a strong immune system, your risk of hepatitis C infection can be resolved naturally.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on finding a natural ingredient for the treatment of hepatitis C which presently affects millions of people globally examined the traditional use of Egyptian artichoke (WEA) for the treatment of HCV-infection and complications.
Injection of water extract of a WEA plant decreased the HCV viral load below the detection level in 12 out of 15 patients. In other words, artichoke exerted strong anti-HCV infection, depending on the state of the severity of the disease.
Furthermore, the water extract normalized the levels of enzymes associated with liver function and damage.
Moreover, The total WEA extract at IC50 ∼ 20 μg ml(-1), inhibited abnormal expression of genes in patients with hepatitis C infection, involving in drug metabolism and synthesis of cholesterol, steroids, and other lipids (CYP2B6 (OH-BUP)) and the formation and breakdown (metabolism) of various molecules and chemicals within cells (CYP2C19 (5-OH-OME)).
WEA was found to be more effective in inhibiting hepatitis C infection compared to the Hepar SL Forte(®) due to the presence of sesquiterpenes versus the abundance of phenolic compounds of the Hepar SL Forte(®).
In chemicals analysis, grosheimol and cynaropicrin, isolated from the WEA showed the most inhibitory effect against HCV with half-maximal effective concentrations (EC50s) in the low micromolar range.
Both tested compounds inhibited HCV entry into target cells in both cell-free infections and cell-cell transmission.
Both compounds belong to the group of sesquiterpene lactones which are found in the WEA but not in the Hepar SL Forte(®).
The results clearly supported the use of WEA in traditional use for the treatment of liver viral infection and complications.
Taken altogether, herbal Artichoke may be considered a functional remedy for the prevention and treatment of HCV infection, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials by Elsebai MF1, Abass K2, Hakkola J3, Atawia AR4, Farag MA. (PubMed)
(2) Pan-genotypic Hepatitis C Virus Inhibition by Natural Products Derived from the Wild Egyptian Artichoke by Elsebai MF1, Koutsoudakis G2, Saludes V2, Pérez-Vilaró G2, Turpeinen A3, Mattila S3, Pirttilä AM4, Fontaine-Vive F5, Mehiri M5, Meyerhans A6, Diez. (PubMed)
(3) Hepatitis C virus and the immune system: a concise review by Gremion C1, Cerny A. (PubMed)
Herbal Andrographis Protects Your Heart Against the Onset of Heart Disease
Herbal Andrographis may process certain bioactive compounds for the prevention and treatment of heart diseases, some scientists suggested.
Heart disease is the medical condition associated with the blood vessels, including coronary artery disease, heart rhythm, and a heart defect caused by the accumulation of plaques.
Plaque made up of cholesterol, fatty molecules, and minerals accumulated in the arteries can cause stiffening and hardening of the arterial wall and narrowing the arteries, affecting the transportation of oxygen risk blood to the heart.
These results suggested that people who follow the Western diet high in saturated and trans fat, red med meat and processed foods and over the use of calcium supplements are associated with the increased risk plaque building up.
Long-term building up plaques can cause substantial damage to the arterial wall, facilitating the onset of heart disease.
According to statistics, heart disease kills more than 2,000 Americans every day and approximately 60 million Americans have heart disease.
The exact causes of heart disease are debatable. Researchers do not why people who over a few decades of following the Western diet, only some are susceptible to heart disease while many do not, even have the same health conditions.
The differentiation suggested that some people may process certain genetic preposition which
can increase the development of heart disease.
Dr. Seka Kathiresan, the lead scientist in the study"Genetics of Human Cardiovascular Disease" Cardiovascular disease encompasses a range of conditions extending from myocardial infarction to congenital heart disease most of which are heritable", and
"ANGPTL3mutations as a cause of familial combined hypolipidemia, BAG mutations for dilated cardiomyopathy, NT5E mutations for arterial calcification, KCNJ5 mutations for hereditary hypertension due to aldosterone-producing adenomas, and KLHL3 or CUL3mutations for hypertension and hyperkalemia".
Other risk factors, according to epidemiological studies include obesity insulin resistance or diabetes, high cholesterol and blood pressure, physically inactive, smoking and eating an unhealthy diet are also associated with disease onset.
However, most people who carry some of the risk factors have never developed heart disease.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
Besides the main ingredient andrographolides, giving the plant a bitter taste, herbal Andrographis also has diterpene lactones, neoandrographolide, andrographolide, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoids viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
In the concern of ischemia-reperfusion (I-R) injury in the increase of the complication of myocardial infarction (MI), researchers at the All India Institute of Medical Sciences conducted a study with an aim to find a natural ingredient or whole herb which processes a cardioprotective effect.
In the rat model, the hydroalcoholic extract of Andrographis paniculata was evaluated against the left anterior descending coronary artery (LADCA) ligation-induced I-R injury of the myocardium.
Selected MI rats were induced by LADCA ligation for 45 min followed by reperfusion for 60 min and divided into five experimental groups viz., sham (saline-treated, but LADCA was not ligated), I-R control (saline-treated + I-R), benazepril (30 mg/kg + I-R), A. paniculata (200 mg/kg per se) and A. paniculata (200 mg/kg + I-R).
* In I-R control group, LADCA ligation showed a significant cardiac dysfunction evidenced by reduced hemodynamic parameters; mean arterial pressure (MAP) and heart rate (HR).
* The I-R control without treatment of the herbal extract expressed a decline of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione (GSH) but enhanced lipid peroxidation product, malondialdehyde (MDA), a marker of oxidative stress.
After 30 days of 200 mg/kg A. paniculata administered orally, the treated group showed favorable improvement of hemodynamic and left the ventricular contractile function, restoration of the myocardial antioxidants and prevention of depletion of myocytes injury marker enzymes along with inhibition of lipid peroxidation.
The results indicated that 200 mg/kg A. paniculata demonstrated a significant cardioprotective activity by inhibiting the adverse effect caused by LADCA in the rat model.
Dr. Ojha SK, the lead author said. "The cardioprotective effects of A. paniculata were found comparable to that of benazepril treatment".
Additionally, in reaffirming the cardioprotective effect of herbal Andrographis, researchers launched an investigation to examine the watery extract of Andrographis paniculata Nees (APN) activity after one hour of the development of myocardial infarction by the formation of thrombus.
13 dogs were included in the study with 6 of the was served as a control group.
Andrographis treatment group showed clinically significant efficacy in the improvement of the myocardial structure surrounding the initially appearing ischemic area.
Andrographis exerted a cardioprotective effect in a reversal of the damaged area by restoring the damaged area.
The degree of myocardial degeneration and necrosis in the central part of the ischemic area was mild. in the treatment, dogs compared to the control.
These observations strongly suggested that APN processes cardioprotection by limiting the expansion of ischemic focus, accelerating the reversibly ischemic myocardium.
Taken altogether, herbal Andrographis may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for the treatment of heart disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Protective effect of hydroalcoholic extract of Andrographis paniculata on ischemia-reperfusion-induced myocardial injury in rats by Ojha SK, Bharti S, Joshi S, Kumari S, Arya DS. (PubMed)
(2) Protective effects of Andrographis paniculata Nees on post-infarction myocardium in experimental dogs by Zhao HY, Fang WY. (PubMed)
(3) Genetics of Human Cardiovascular Disease by Sekar Kathiresan1, and Deepak Srivastava. (PMC)
Heart disease is the medical condition associated with the blood vessels, including coronary artery disease, heart rhythm, and a heart defect caused by the accumulation of plaques.
Plaque made up of cholesterol, fatty molecules, and minerals accumulated in the arteries can cause stiffening and hardening of the arterial wall and narrowing the arteries, affecting the transportation of oxygen risk blood to the heart.
These results suggested that people who follow the Western diet high in saturated and trans fat, red med meat and processed foods and over the use of calcium supplements are associated with the increased risk plaque building up.
Long-term building up plaques can cause substantial damage to the arterial wall, facilitating the onset of heart disease.
According to statistics, heart disease kills more than 2,000 Americans every day and approximately 60 million Americans have heart disease.
The exact causes of heart disease are debatable. Researchers do not why people who over a few decades of following the Western diet, only some are susceptible to heart disease while many do not, even have the same health conditions.
The differentiation suggested that some people may process certain genetic preposition which
can increase the development of heart disease.
Dr. Seka Kathiresan, the lead scientist in the study"Genetics of Human Cardiovascular Disease" Cardiovascular disease encompasses a range of conditions extending from myocardial infarction to congenital heart disease most of which are heritable", and
"ANGPTL3mutations as a cause of familial combined hypolipidemia, BAG mutations for dilated cardiomyopathy, NT5E mutations for arterial calcification, KCNJ5 mutations for hereditary hypertension due to aldosterone-producing adenomas, and KLHL3 or CUL3mutations for hypertension and hyperkalemia".
Other risk factors, according to epidemiological studies include obesity insulin resistance or diabetes, high cholesterol and blood pressure, physically inactive, smoking and eating an unhealthy diet are also associated with disease onset.
However, most people who carry some of the risk factors have never developed heart disease.
Andrographis paniculata is also known as Andrographis is a herbaceous plant, genus Andrographis, belonging to the family Acanthaceae, native to India and Sri Lanka.
The plant has been used in traditional Siddha and Ayurvedic in treating the common cold, flu, upper respiratory infections, infectious diseases, diarrhea, dysentery, cholera, pneumonia, swollen lymph nodes, leprosy, bronchitis, sore throats, tuberculosis, chicken pox, etc.
Besides the main ingredient andrographolides, giving the plant a bitter taste, herbal Andrographis also has diterpene lactones, neoandrographolide, andrographolide, 14-doexy-11, 12-didehydro andrographolide, etc., flavonoids viz., oroxylin, wogonin, andrographidines A, B, C, D, E, F.
In the concern of ischemia-reperfusion (I-R) injury in the increase of the complication of myocardial infarction (MI), researchers at the All India Institute of Medical Sciences conducted a study with an aim to find a natural ingredient or whole herb which processes a cardioprotective effect.
In the rat model, the hydroalcoholic extract of Andrographis paniculata was evaluated against the left anterior descending coronary artery (LADCA) ligation-induced I-R injury of the myocardium.
Selected MI rats were induced by LADCA ligation for 45 min followed by reperfusion for 60 min and divided into five experimental groups viz., sham (saline-treated, but LADCA was not ligated), I-R control (saline-treated + I-R), benazepril (30 mg/kg + I-R), A. paniculata (200 mg/kg per se) and A. paniculata (200 mg/kg + I-R).
* In I-R control group, LADCA ligation showed a significant cardiac dysfunction evidenced by reduced hemodynamic parameters; mean arterial pressure (MAP) and heart rate (HR).
* The I-R control without treatment of the herbal extract expressed a decline of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione (GSH) but enhanced lipid peroxidation product, malondialdehyde (MDA), a marker of oxidative stress.
After 30 days of 200 mg/kg A. paniculata administered orally, the treated group showed favorable improvement of hemodynamic and left the ventricular contractile function, restoration of the myocardial antioxidants and prevention of depletion of myocytes injury marker enzymes along with inhibition of lipid peroxidation.
The results indicated that 200 mg/kg A. paniculata demonstrated a significant cardioprotective activity by inhibiting the adverse effect caused by LADCA in the rat model.
Dr. Ojha SK, the lead author said. "The cardioprotective effects of A. paniculata were found comparable to that of benazepril treatment".
Additionally, in reaffirming the cardioprotective effect of herbal Andrographis, researchers launched an investigation to examine the watery extract of Andrographis paniculata Nees (APN) activity after one hour of the development of myocardial infarction by the formation of thrombus.
13 dogs were included in the study with 6 of the was served as a control group.
Andrographis treatment group showed clinically significant efficacy in the improvement of the myocardial structure surrounding the initially appearing ischemic area.
Andrographis exerted a cardioprotective effect in a reversal of the damaged area by restoring the damaged area.
The degree of myocardial degeneration and necrosis in the central part of the ischemic area was mild. in the treatment, dogs compared to the control.
These observations strongly suggested that APN processes cardioprotection by limiting the expansion of ischemic focus, accelerating the reversibly ischemic myocardium.
Taken altogether, herbal Andrographis may be considered a functional food for the prevention and an adjunct therapy combined with the primary medicine for the treatment of heart disease.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Protective effect of hydroalcoholic extract of Andrographis paniculata on ischemia-reperfusion-induced myocardial injury in rats by Ojha SK, Bharti S, Joshi S, Kumari S, Arya DS. (PubMed)
(2) Protective effects of Andrographis paniculata Nees on post-infarction myocardium in experimental dogs by Zhao HY, Fang WY. (PubMed)
(3) Genetics of Human Cardiovascular Disease by Sekar Kathiresan1, and Deepak Srivastava. (PMC)
Herbal Alfalfa, the Immunomodulatory Natural Whole Food Medicine
Alfalfa is a flowering plant in the genus Medicago, belonging to the family Fabaceae, The plants have been cultivated all over the world as hay for cattle feeding, and used in traditional medicine over thousands of year to treat high cholesterol, asthma, osteoarthritis, rheumatoid arthritis, diabetes, enhance digestive system, bleeding disorder, kidney, and urinary tract infection, etc. North Americal aboriginal has used Alfalfa seed as food, such as making bread and mush.
The immunomodulatory effect is a function of the immune system involved many reactions, including antimicrobial organisms against infection and inflammation, modulated genes expression.......This modulation may also be induced by the neurohormonal system.
Alfalfa may be a potential herbal medicine used for enhanced immune systems for fighting against the forming of free radicals and invasion of foreign substances through its immunomodulatory effects.
Polysavone, a natural extract from alfalfa, induced the proliferation of T and B white blood cells, lymphocytes and improved antibody against viral invasion significantly in comparison to the control group, according to the animal study.
Dr. Xiaofang Dong at the Qiqihar University said, " Polysavone may decrease abdominal fat deposition and enhance immunity without an adverse effect on the performance of broiler chickens"
In a total of A total of 360 1-d-old male commercial Arbor Acre broiler chickens, dietary polysavone (Alfalfa extract) in comparison to chlortetracycline supplementation, polysavone group showed a excellent scavenging activity in inhibited free radical expression, particular for 1,1-diphenyl-2-picrylhydrazyl and superoxide anion radicals, through it The immunomodulatory effects in improved immune function in compared chlortetracycline supplementation group.
Furthermore, alfalfa flavonoids extract (AFE) also promoted immune function in regulating the population of microbe, enhancing antioxidant properties by increasing antioxidase activity and affecting immunity by changing the proportion of white blood cells and Innate immunity.
Taking all together, alfalfa may be effective in the promoted immune system fighting against the forming of free radical and microbial infection, but human trials are necessary to confirm this validation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Effect of Polysavone (Alfalfa Extract) on Abdominal Fat Deposition and Immunity in Broiler Chickens(Researchgate)
(2) Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens by Dong XF1, Gao WW, Su JL, Tong JM, Zhang Q.(PubMed)
(3) Effects of alfalfa flavonoids on the production performance, immune system, and ruminal fermentation of dairy cows by Zhan J1, Wu C1, Liu M1, Su X1, Zhan K1, Zhang C1, Zhao G1.(PubMed)
The immunomodulatory effect is a function of the immune system involved many reactions, including antimicrobial organisms against infection and inflammation, modulated genes expression.......This modulation may also be induced by the neurohormonal system.
Alfalfa may be a potential herbal medicine used for enhanced immune systems for fighting against the forming of free radicals and invasion of foreign substances through its immunomodulatory effects.
Polysavone, a natural extract from alfalfa, induced the proliferation of T and B white blood cells, lymphocytes and improved antibody against viral invasion significantly in comparison to the control group, according to the animal study.
Dr. Xiaofang Dong at the Qiqihar University said, " Polysavone may decrease abdominal fat deposition and enhance immunity without an adverse effect on the performance of broiler chickens"
In a total of A total of 360 1-d-old male commercial Arbor Acre broiler chickens, dietary polysavone (Alfalfa extract) in comparison to chlortetracycline supplementation, polysavone group showed a excellent scavenging activity in inhibited free radical expression, particular for 1,1-diphenyl-2-picrylhydrazyl and superoxide anion radicals, through it The immunomodulatory effects in improved immune function in compared chlortetracycline supplementation group.
Furthermore, alfalfa flavonoids extract (AFE) also promoted immune function in regulating the population of microbe, enhancing antioxidant properties by increasing antioxidase activity and affecting immunity by changing the proportion of white blood cells and Innate immunity.
Taking all together, alfalfa may be effective in the promoted immune system fighting against the forming of free radical and microbial infection, but human trials are necessary to confirm this validation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Effect of Polysavone (Alfalfa Extract) on Abdominal Fat Deposition and Immunity in Broiler Chickens(Researchgate)
(2) Effects of dietary polysavone (Alfalfa extract) and chlortetracycline supplementation on antioxidation and meat quality in broiler chickens by Dong XF1, Gao WW, Su JL, Tong JM, Zhang Q.(PubMed)
(3) Effects of alfalfa flavonoids on the production performance, immune system, and ruminal fermentation of dairy cows by Zhan J1, Wu C1, Liu M1, Su X1, Zhan K1, Zhang C1, Zhao G1.(PubMed)
Sunday, November 3, 2019
Anise, The Herb Which Exerts Antinociceptive Activity Against Primary Dysmenorrhea, Scientist Find
Herbal Anise may process an antinociceptive activity in reducing the expression of primary dysmenorrhea, some scientists suggested.
Primary dysmenorrhea pain is a menstrual pain caused by sensory neurons stimulus triggered by overproduction prostaglandins, hormones that lead to uterus contract before or during menstruation.
Antinociceptive activity is an action or process of blocking the painful or injurious stimulus by sensory neurons.
Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen.
In traditional Chinese medicine, dysmenorrhea is defined as a pain in the lower abdomen that can spread over to the whole abdomen and lumbosacral region, depending on the diagnosis.
According to statistics, primary dysmenorrhea affects more than 50% of women in late adolescence and the early 20s. Most primary dysmenorrhea appears 6 to 12 months after the first period due to immature of the reproductive organs of young girls,
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region.
The popular herb has been used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, antispasmodic, carminative, digestive, expectorant, stimulant and tonic agent and to treat head-lice and mites, increase blood pressure, prevent formation of gas in the gastrointestinal tract,.... and menstrual cramps.
The Chemical Ingredients
Besides the main ingredient Anethole, herbal anise also contains, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
In the finding of natural ingredients treat primary dysmenorrhea without inducing side effects, Dr. Khodakrami Nahid, MSM and colleague conducted a study to examine the effect of an Iranian herbal drug in the treatment of primary dysmenorrhea.
The randomized, double-blind, placebo-controlled pilot trial among 180 female students at Isfahan University dormitory aged 18 to 27.
Participants were randomly divided into three groups: herbal drugs were given 500 mg of highly purified saffron, celery seed, and anise (SCA) extracts three times a day for three days, starting from the onset of bleeding or pain, mefenamic acid, and placebo.
After following the participants for two to three cycles from the beginning of menstruation through the three days of bleeding and the severity and duration of pain at 2 and 3 months were measured.
At the final report of the study, researchers filed,
* Women received Anise extract and mefenamic acid showed a statistically significant reduction in pain scores and pain duration scores.
* The decrease in pain score was reflected by a significant reduction in other herbal drug use among the treatment groups compared to the placebo group but lesser compared to the Anise group.
* Application of Anise extract demonstrated a magnitude of the reduction which is significantly greater compared to mefenamic acid and placebo groups.
* However, both herbal drugs and mefenamic acid effectively relieved menstrual pain as compared with the placebo.
These results suggested that herbal Anise processed strong antinociceptive activity against pain caused by primary dysmenorrhea may be considered as a functional herb for the treatment of primary dysmenorrhea.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. Herbal combination for primary dysmenorrhea by Tori Hudson, ND
2. The effect of an Iranian herbal drug on primary dysmenorrhea: a clinical controlled trial.
Primary dysmenorrhea pain is a menstrual pain caused by sensory neurons stimulus triggered by overproduction prostaglandins, hormones that lead to uterus contract before or during menstruation.
Antinociceptive activity is an action or process of blocking the painful or injurious stimulus by sensory neurons.
Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen.
In traditional Chinese medicine, dysmenorrhea is defined as a pain in the lower abdomen that can spread over to the whole abdomen and lumbosacral region, depending on the diagnosis.
According to statistics, primary dysmenorrhea affects more than 50% of women in late adolescence and the early 20s. Most primary dysmenorrhea appears 6 to 12 months after the first period due to immature of the reproductive organs of young girls,
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to Egypt and the Mediterranean region.
The popular herb has been used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, antispasmodic, carminative, digestive, expectorant, stimulant and tonic agent and to treat head-lice and mites, increase blood pressure, prevent formation of gas in the gastrointestinal tract,.... and menstrual cramps.
The Chemical Ingredients
Besides the main ingredient Anethole, herbal anise also contains, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
In the finding of natural ingredients treat primary dysmenorrhea without inducing side effects, Dr. Khodakrami Nahid, MSM and colleague conducted a study to examine the effect of an Iranian herbal drug in the treatment of primary dysmenorrhea.
The randomized, double-blind, placebo-controlled pilot trial among 180 female students at Isfahan University dormitory aged 18 to 27.
Participants were randomly divided into three groups: herbal drugs were given 500 mg of highly purified saffron, celery seed, and anise (SCA) extracts three times a day for three days, starting from the onset of bleeding or pain, mefenamic acid, and placebo.
After following the participants for two to three cycles from the beginning of menstruation through the three days of bleeding and the severity and duration of pain at 2 and 3 months were measured.
At the final report of the study, researchers filed,
* Women received Anise extract and mefenamic acid showed a statistically significant reduction in pain scores and pain duration scores.
* The decrease in pain score was reflected by a significant reduction in other herbal drug use among the treatment groups compared to the placebo group but lesser compared to the Anise group.
* Application of Anise extract demonstrated a magnitude of the reduction which is significantly greater compared to mefenamic acid and placebo groups.
* However, both herbal drugs and mefenamic acid effectively relieved menstrual pain as compared with the placebo.
These results suggested that herbal Anise processed strong antinociceptive activity against pain caused by primary dysmenorrhea may be considered as a functional herb for the treatment of primary dysmenorrhea.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. Herbal combination for primary dysmenorrhea by Tori Hudson, ND
2. The effect of an Iranian herbal drug on primary dysmenorrhea: a clinical controlled trial.
Herbal Artichoke May Cure Non Alcoholic Liver Disease (NAFLD), Human Studies Suggest
On seeking natural therapy with no side effects, scientists may have found a herbal remedy for the prevention and treatment of nonalcoholic liver disease (NAFLD), according to studies.
Nonalcoholic liver disease is a chronic condition caused by fat accumulated over time in the liver, affecting people who drink little to no alcohol.
In other words, if you have fat that makes up over 5% of the liver, you are considered to have fatty liver disease.
Nonalcoholic liver disease can be classified into the noninflammatory fatty liver and inflammatory liver steatohepatitis.
Most patients with nonalcoholic fatty liver disease are asymptomatic. However, in the later stage, patients may experience symptoms of enlarged liver, persistent fatigue and pain in the upper right abdomen, depending on the formation of scars.
According to the statistics provided by the Canadian Liver Foundation, more than 50% of Canadians are overweight and 75% of obese individuals are at risk of developing a simple fatty liver, including 23% of them will develop fatty liver with inflammation sometimes during their lifetime.
According to the epidemiological studies, patients with nonalcoholic liver disease have elevated levels of liver enzymes gamma-glutamyl transferase (GGT), Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) which are the markers used to predict the severity of liver disease including fatty liver.
A blood test is required if your doctor suspects you might develop fatty liver disease, including NAFLD.
Other tests for diagnosis of liver fatty disease may include ultrasound, computed tomography (CT), proton magnetic resonance spectroscopy (H-MRS), and magnetic resonance imaging (MRI).
The exact causes of nonalcoholic fatty liver disease are not identified. However, some researchers suggested unhealthy diet-induced obesity may be a major cause of the widespread NAFLD in the Western world.
Dr. Al-Dayyat HM, the lead scientist in the examination of the non-alcoholic fatty liver disease and associated dietary and lifestyle risk factors, said, "Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide with a reported prevalence ranging 20-30% depending on the studied populations".
And, "The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. NAFLD patients are at increased risk of cardiovascular and liver-related mortality".
The findings strongly suggested if you are obese, you are at a substantially higher risk of fatty liver disease, compared to healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the course od finding a herbal remedy for the treatment of nonalcoholic liver disease (NAFLD), researchers evaluated the potential to attenuate lipid disturbances of Jerusalem artichoke (JA).
Selected Wistar rats included in the study were fed a control diet, a 60 % fructose-enriched diet (FRU), or an FRU with 10 % JA (n 6-7) for 4 weeks.
According to liver samples collected for biochemical and global gene expression analysis, pretreatment of dietary JA supplementation showed strong activity against hepatic TAG accumulation induced by the FRU.
Futhermore, JA also demonstrated significant inhibition of inflammation-inducing the expression of proteins associated with liver fatty acid synthesis, and the development of liver fibrosis.
The results suggested that JA processes beneficial effects in the prevention of non-alcoholic fatty liver disease at molecular levels.
In order to collect more information about artichoke anti-non-alcoholic fatty liver disease, scientists investigated the artichoke leaf extract (ALE) potential hepatoprotective activity in patients with NAFLD.
100 subjects with ultrasound-diagnosed NAFLD randomized to either ALE 600 mg daily or placebo for a 2-month period were included in the randomized double-blind placebo-controlled parallel-group trial.
According to the results from 90 patients who completed the study (49 ALE and 41 placeboes), the intake of ALE did not exert any side effects.
ALE at the end of the experiment displays a liver protective effect by increasing the hepatic vein flow reducing portal vein diameter (p < .001) and liver size (p < .001).
Injection of ALE also inhibited the liver damage and oxidative stress markers.
Moreover, the artichoke leaf extract also is found to reduce the levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and triglyceride concentrations, according to the assays.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of non-alcoholic liver disease, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References(1) Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats by Chang WC1, Jia H2, Aw W2, Saito K2, Hasegawa S3, Kato H. (PubMed)
(2) Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial by Panahi Y1, Kianpour P2, Mohtashami R3, Atkin SL4, Butler AE5, Jafari R6, Badeli R7, Sahebkar A. (PubMed)
Nonalcoholic liver disease is a chronic condition caused by fat accumulated over time in the liver, affecting people who drink little to no alcohol.
In other words, if you have fat that makes up over 5% of the liver, you are considered to have fatty liver disease.
Nonalcoholic liver disease can be classified into the noninflammatory fatty liver and inflammatory liver steatohepatitis.
Most patients with nonalcoholic fatty liver disease are asymptomatic. However, in the later stage, patients may experience symptoms of enlarged liver, persistent fatigue and pain in the upper right abdomen, depending on the formation of scars.
According to the statistics provided by the Canadian Liver Foundation, more than 50% of Canadians are overweight and 75% of obese individuals are at risk of developing a simple fatty liver, including 23% of them will develop fatty liver with inflammation sometimes during their lifetime.
According to the epidemiological studies, patients with nonalcoholic liver disease have elevated levels of liver enzymes gamma-glutamyl transferase (GGT), Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) which are the markers used to predict the severity of liver disease including fatty liver.
A blood test is required if your doctor suspects you might develop fatty liver disease, including NAFLD.
Other tests for diagnosis of liver fatty disease may include ultrasound, computed tomography (CT), proton magnetic resonance spectroscopy (H-MRS), and magnetic resonance imaging (MRI).
The exact causes of nonalcoholic fatty liver disease are not identified. However, some researchers suggested unhealthy diet-induced obesity may be a major cause of the widespread NAFLD in the Western world.
Dr. Al-Dayyat HM, the lead scientist in the examination of the non-alcoholic fatty liver disease and associated dietary and lifestyle risk factors, said, "Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide with a reported prevalence ranging 20-30% depending on the studied populations".
And, "The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. NAFLD patients are at increased risk of cardiovascular and liver-related mortality".
The findings strongly suggested if you are obese, you are at a substantially higher risk of fatty liver disease, compared to healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the course od finding a herbal remedy for the treatment of nonalcoholic liver disease (NAFLD), researchers evaluated the potential to attenuate lipid disturbances of Jerusalem artichoke (JA).
Selected Wistar rats included in the study were fed a control diet, a 60 % fructose-enriched diet (FRU), or an FRU with 10 % JA (n 6-7) for 4 weeks.
According to liver samples collected for biochemical and global gene expression analysis, pretreatment of dietary JA supplementation showed strong activity against hepatic TAG accumulation induced by the FRU.
Futhermore, JA also demonstrated significant inhibition of inflammation-inducing the expression of proteins associated with liver fatty acid synthesis, and the development of liver fibrosis.
The results suggested that JA processes beneficial effects in the prevention of non-alcoholic fatty liver disease at molecular levels.
In order to collect more information about artichoke anti-non-alcoholic fatty liver disease, scientists investigated the artichoke leaf extract (ALE) potential hepatoprotective activity in patients with NAFLD.
100 subjects with ultrasound-diagnosed NAFLD randomized to either ALE 600 mg daily or placebo for a 2-month period were included in the randomized double-blind placebo-controlled parallel-group trial.
According to the results from 90 patients who completed the study (49 ALE and 41 placeboes), the intake of ALE did not exert any side effects.
ALE at the end of the experiment displays a liver protective effect by increasing the hepatic vein flow reducing portal vein diameter (p < .001) and liver size (p < .001).
Injection of ALE also inhibited the liver damage and oxidative stress markers.
Moreover, the artichoke leaf extract also is found to reduce the levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, and triglyceride concentrations, according to the assays.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of non-alcoholic liver disease, pending to the confirmation of larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References(1) Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats by Chang WC1, Jia H2, Aw W2, Saito K2, Hasegawa S3, Kato H. (PubMed)
(2) Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial by Panahi Y1, Kianpour P2, Mohtashami R3, Atkin SL4, Butler AE5, Jafari R6, Badeli R7, Sahebkar A. (PubMed)
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