The topical use of essential oil and intake of cinnamon in patients are found to express antimicrobial effect.
The essential oil found from cinnamomum zeylanicum, in the influenza and postinfluenza bacterial pneumonia infections resisted conventional antimicrobial agents, inhibited effectively against H1N1 and HSV1 viruses.
According to the study by the Kings and St Thomas's Hospital, natural essential oils extracted from cinnamon expressed antimicrobial activity among three oils against Escherichia coli , Staphylococcus aureus , Aspergillus oryzae , and Penicillium digitatum.
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
Dr. Liu Q, the lead author at the Liu Q, said," cinnamon,... possessed significant antibacterial and antifungal activities against food spoilage bacteria like Bacillus subtilis and Pseudomonas fluorescens, pathogens like Staphylococcus aureus and Vibrio parahaemolyticus, harmful fungi like Aspergillus flavus".
In vitro, trans-cinnamaldehyde showed to inhibit Clostridium difficile infection to the spore-forming bacterium.
Cinnamon and its essential oil may be the natural agent in use for the prevention and treatment of microbial infection. Intake of whole herb and supplement should be taken with care. Overdoses have seen to induce toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Synergistic antimicrobial activities of natural essential oils with chitosan films by Wang L1, Liu F, Jiang Y, Chai Z, Li P, Cheng Y, Jing H, Leng X.(PubMed)
(2) Antibacterial and Antifungal Activities of Spices by Liu Q1, Meng X2, Li Y3, Zhao CN4, Tang GY5, Li HB6,7.(PubMed)
(3) Antimicrobial activity of natural products against Clostridium difficile in vitro by Roshan N1, Riley TV1,2,3,4, Hammer KA1.(PubMed)
(4) Antibacterial, antifungal, and antiviral effects of three essential oil blends by Brochot A1, Guilbot A1, Haddioui L2, Roques C2,3.(PubMed)
Sunday, January 12, 2020
Saturday, January 11, 2020
The Effects of Herbal Chaste tree berry (Vitex agnus-castus) on Propionibacterium acne
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region. It has been used in herbal medicine for thousands of years as an aphrodisiac herb and is considered as Queen herb in treating menstrual problems and discomforts by taking it in a prolonged period of time. There was a report that reports chaste tree berry stems and leaves used by women as bedding "to cool the heat of lust" during the time of the Thesmophoria,
Chemical constituents
1. β-citronellol
2. Labdane-type diterpenoids,
3. Halimane-type diterpenoid,
4. Oleanane-type triterpenoids,
5. Ursane-type triterpenoids,
6. Sesquiterpenoid,
7. Flavonoid
8. Viteagnusins C, D, E, F, G, and H
9. Abietane-type diterpenoids
Propionibacterium acne is a type of acne due to infection of aerotolerant anaerobic, Gram-positive bacterium (rod) or as a result of chronic blepharitis and endophthalmitis.
Vitex agnus-castus has long been used for the treatment of hormonally induced acne in herbal medicine(1) with mild or no adverse side effects (2). Vitex negundo, a five-leaved chaste tree extract, according to the study by The Institute of Science, India, showed significant inhibition of lipase activity and a number of P. acne(3).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The genus Vitex: A review by Rani A1, Sharma A2. (PubMed)
(2) Vitex agnus castus: a systematic review of adverse events by Daniele C1, Thompson Coon J, Pittler MH, Ernst E.(PubMed)
(3) Inhibition of Propionibacterium acnes lipase by extracts of Indian medicinal plants by Patil V1, Bandivadekar A, Debjani D.(PubMed)
Chemical constituents
1. β-citronellol
2. Labdane-type diterpenoids,
3. Halimane-type diterpenoid,
4. Oleanane-type triterpenoids,
5. Ursane-type triterpenoids,
6. Sesquiterpenoid,
7. Flavonoid
8. Viteagnusins C, D, E, F, G, and H
9. Abietane-type diterpenoids
Propionibacterium acne is a type of acne due to infection of aerotolerant anaerobic, Gram-positive bacterium (rod) or as a result of chronic blepharitis and endophthalmitis.
Vitex agnus-castus has long been used for the treatment of hormonally induced acne in herbal medicine(1) with mild or no adverse side effects (2). Vitex negundo, a five-leaved chaste tree extract, according to the study by The Institute of Science, India, showed significant inhibition of lipase activity and a number of P. acne(3).
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) The genus Vitex: A review by Rani A1, Sharma A2. (PubMed)
(2) Vitex agnus castus: a systematic review of adverse events by Daniele C1, Thompson Coon J, Pittler MH, Ernst E.(PubMed)
(3) Inhibition of Propionibacterium acnes lipase by extracts of Indian medicinal plants by Patil V1, Bandivadekar A, Debjani D.(PubMed)
Herbal Coltsfoot (Tussilago farfara) In Reducing the Risk and Progression of Lung Cancer In Vitro
Cancer is a class of diseases caused by cell growth and multiplication disorderly and uncontrollably due to the alternation of the DNA.
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
The lung is a vital organ located near the backbone on either side of the heart with major functions to inhale oxygen from the air to the bloodstream that nourishes the body cells and exhale carbon dioxide from the bloodstream.
Lung cancer is a chronic condition characterized by cell growth irregularly and disorderly in the lung tissue.
Most cases of lung cancer caused by the alternation of calls DNA begin in the cells on the surface of the inner lining of the lung.
At the advanced stage, the cancer cell from the lung can travel a distance away to infect other healthy tissue and organs through the circulation of fluid and blood, leading to the secondary metastasis.
According to statistics, in 2017, 28,600 Canadians were diagnosed with lung cancer, representing 14% of all new cancer cases. Also in 2017, lung cancer caused the death of 21,100 Canadians.
Smoking although it is a major cause of lung cancer, however, not all lung cancer patients with lung cancer are smokers. Nonsmokers' lung cancer may be caused by exposure to radon, secondhand smoke, air pollution, or other factors.
Some researchers suggested that lung cancer in many incidences is associated with oxidative stress as found in advanced lung cancer patients.
Dr. Filaire E the lead scientist in the examination of the oxidative stress in the risk lung cancer said, "Oxidative stress also plays important roles in the pathogenesis of many diseases, including aging, degenerative disease, and cancer. Among cancers, lung cancer is the leading cause of cancer in the Western world".
And, "Distinct measures of primary and secondary prevention have been investigated to reduce the risk of morbidity and mortality caused by lung cancer. Among them, it seems that physical activity and nutrition have some beneficial effects".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of lung disease, researchers examined the effects of purified a polysaccharide, TFPB1, from the flower buds of Tussilago farfara on lung cancer.
In vitro, TFPB1 not only inhibited cell proliferation but also induced cancer cell apoptosis in of A549 cells.
More precisely, TFPB1 kills lung cancer cells by inhibiting the expression of kinase and proteins such as phosphorylation of Akt and Bcl-2 expression involved in multiple cellular processes including apoptosis and exhibiting the protein associated with caspase involved in pro-apoptosis such as Bax expression.
Based on the findings, researchers aid, "TFPB1 exhibited anti-proliferative and anti-apoptotic effect partly depending on the suppression of Akt signaling pathway." and "These findings provided us a potential chemotherapeutic strategy for the treatment of human non-small cell lung cancer".
Taken altogether, coltsfoot may be considered a remedy for the treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Structural characterization of a polysaccharide from the flower buds of Tussilago farfara, and its effect on proliferation and apoptosis of A549 human non-small lung cancer cell line by Qu H1, Yang W2, Li J. (PubMed)
(2) Lung cancer: what are the links with oxidative stress, physical activity and nutrition by Filaire E1, Dupuis C, Galvaing G, Aubreton S, Laurent H, Richard R, Filaire M. (PubMed)
After colonizing the entire tissues of the specific organ, the oversize tumor cell can travel a distance away from the originated site to invade other healthy tissues, via lymph or blood.
The most advanced stage of cancer may result in the death of the patients.
The lung is a vital organ located near the backbone on either side of the heart with major functions to inhale oxygen from the air to the bloodstream that nourishes the body cells and exhale carbon dioxide from the bloodstream.
Lung cancer is a chronic condition characterized by cell growth irregularly and disorderly in the lung tissue.
Most cases of lung cancer caused by the alternation of calls DNA begin in the cells on the surface of the inner lining of the lung.
At the advanced stage, the cancer cell from the lung can travel a distance away to infect other healthy tissue and organs through the circulation of fluid and blood, leading to the secondary metastasis.
According to statistics, in 2017, 28,600 Canadians were diagnosed with lung cancer, representing 14% of all new cancer cases. Also in 2017, lung cancer caused the death of 21,100 Canadians.
Smoking although it is a major cause of lung cancer, however, not all lung cancer patients with lung cancer are smokers. Nonsmokers' lung cancer may be caused by exposure to radon, secondhand smoke, air pollution, or other factors.
Some researchers suggested that lung cancer in many incidences is associated with oxidative stress as found in advanced lung cancer patients.
Dr. Filaire E the lead scientist in the examination of the oxidative stress in the risk lung cancer said, "Oxidative stress also plays important roles in the pathogenesis of many diseases, including aging, degenerative disease, and cancer. Among cancers, lung cancer is the leading cause of cancer in the Western world".
And, "Distinct measures of primary and secondary prevention have been investigated to reduce the risk of morbidity and mortality caused by lung cancer. Among them, it seems that physical activity and nutrition have some beneficial effects".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of lung disease, researchers examined the effects of purified a polysaccharide, TFPB1, from the flower buds of Tussilago farfara on lung cancer.
In vitro, TFPB1 not only inhibited cell proliferation but also induced cancer cell apoptosis in of A549 cells.
More precisely, TFPB1 kills lung cancer cells by inhibiting the expression of kinase and proteins such as phosphorylation of Akt and Bcl-2 expression involved in multiple cellular processes including apoptosis and exhibiting the protein associated with caspase involved in pro-apoptosis such as Bax expression.
Based on the findings, researchers aid, "TFPB1 exhibited anti-proliferative and anti-apoptotic effect partly depending on the suppression of Akt signaling pathway." and "These findings provided us a potential chemotherapeutic strategy for the treatment of human non-small cell lung cancer".
Taken altogether, coltsfoot may be considered a remedy for the treatment of lung cancer, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Structural characterization of a polysaccharide from the flower buds of Tussilago farfara, and its effect on proliferation and apoptosis of A549 human non-small lung cancer cell line by Qu H1, Yang W2, Li J. (PubMed)
(2) Lung cancer: what are the links with oxidative stress, physical activity and nutrition by Filaire E1, Dupuis C, Galvaing G, Aubreton S, Laurent H, Richard R, Filaire M. (PubMed)
Herbal Artichoke, Protects Your Upper Digestive Tract Against Functional Dyspepsia (FD)
Functional dyspepsia (FD) is a chronic condition characterized by burning sensation caused by uncoordinated and ineffectual emptying of the upper digestive tract with no measurable structural abnormalities.
Functional dyspepsia (FD) are subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).
According to statistics, approximately 20-45% of Canadians have such conditions, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.
The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice and long term use of medications may have strong implications in the onset of the syndrome.
Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD, a sour taste in the mouth are the most common symptoms of functional dyspepsia.
If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.
Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habits in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".
And, "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".
The finding strongly suggested by following a healthy diet pattern, FD may be preventable.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On finding a natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.
The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).
After 14 days, supplement treatment showed a significant amelioration of FD, compared to placebo.
SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to placebo.
Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".
In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).
The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.
ALE improved the overall symptom significantly over the 6 weeks compared to the placebo
Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.
Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "he ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending to the confirmation of a larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functionaldyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)
Functional dyspepsia (FD) are subdivided into two types: postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS).
According to statistics, approximately 20-45% of Canadians have such conditions, but only a low percentage of patients seek help from physicians. and functional dyspepsia accounts for 62.5% of dyspepsia in a population of black African patients, compared to other races.
The exact causes of functional dyspepsia are unidentified. Some researchers suggested that excessive acid secretion, inflammation, food allergies, unhealthy lifestyle choice and long term use of medications may have strong implications in the onset of the syndrome.
Pain, digestive discomforts such as fullness and bloating, excessive burping, nausea, and sometimes vomiting GERD, a sour taste in the mouth are the most common symptoms of functional dyspepsia.
If you experience some of the aforementioned symptoms, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that unhealthy dietary habits are one of the major risk factors associated with the onset of FD in the world.
Dr. Ji-Hao Xu, the lead scientist in the assessment of dietary habits in the risk of FD, wrote, "Unhealthy dietary habits were more prevalent in the FD group than in the control groups (75.86% versus 37.50%; p<0.001). FD was found to be associated with irregular mealtime, dining out, fatty food, sweet food, and coffee (p<0.05). The impact of each dietary factor varied with FD subtypes".
And, "Certain types of dietary habits were positively correlated with the prevalence of FD. FD subtypes showed relatively different associations with dietary factors".
The finding strongly suggested by following a healthy diet pattern, FD may be preventable.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On finding a natural therapeutics for the treatment of functional dyspepsia (FD), researchers compared the efficacy of ginger and artichoke supplementation (SG) versus placebo in the treatment of FD.
The prospective multicentre, double-blind, randomized, placebo-controlled, parallel-group comparison of the supplement and placebo over a period of 4 weeks included 126 FD patients given 2 capsules/day (before lunch and dinner (supplementation/placebo: 65/61).
After 14 days, supplement treatment showed a significant amelioration of FD, compared to placebo.
SG treatment group also showed a significant reduction of nausea, epigastric fullness, epigastric pain, and bloating compared to placebo.
Dr.Giacosa A, the lead scientist wrote, "The association between ginger and artichoke leaf extracts appears safe and efficacious in the treatment of FD and could represent a promising treatment for this disease".
In order to reveal more information about artichoke anti-FD property, researchers assessed the efficacy of artichoke leaf extract (ALE) in the treatment of patients with functional dyspepsia (FD).
The double-blind, randomized controlled trial (RCT) included 247 patients with functional dyspepsia treated with either a commercial ALE preparation (2 x 320 mg plant extract t.d.s.) or a placebo.
ALE improved the overall symptom significantly over the 6 weeks compared to the placebo
Similarly, patients treated with ALE also showed significantly greater improvement in the global quality-of-life scores (NDI) compared to the placebo.
Dr. Holtmann G, the lead scientist after taking into account co and confounders wrote in the final report, "he ALE preparation tested was significantly better than the placebo in alleviating symptoms and improving the disease-specific quality of life in patients with functional dyspepsia".
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of functional dyspepsia (FD), pending to the confirmation of a larger sample and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial by Giacosa A1, Guido D2, Grassi M2, Riva A3, Morazzoni P3, Bombardelli E3, Perna S4, Faliva MA4, Rondanelli M. (PubMed)
(2) Efficacy of artichoke leaf extract in the treatment of patients with functionaldyspepsia: a six-week placebo-controlled, double-blind, multicentre trial by Holtmann G1, Adam B, Haag S, Collet W, Grünewald E, Windeck T. (PubMed)
(3) Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area by Xu JH1, Lai Y1, Zhuang LP2, Huang CZ1, Li CQ1, Chen QK1, Yu T1. (PubMed)
Friday, January 10, 2020
Herbal Catnip in Ameliorated Risk and Treatment of Lung Cancer
Catnip may have a potential and substantial effect in reduced risk and treatment of lung cancer, some scientists suggested.
Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, used in herbal medicine as insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, colds and flu, skin irritations stimulate sweating, promote menstruation, etc..
Ingredients
Terpenoid nepetalactone, α-Pinene, β-Pinene, Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone, Nepetalactone, etc..
Lung cancer is a medical condition characterized by irregular cell growth in the tissues of the lung. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.
According to statistics, In 2015, approximately 26,600 Canadians will be diagnosed with lung cancer and 20,900 will die of it.
According to the investigation of the anti-cancer effect of extracts isolated from catnip containing sub-fractions (ND-1-ND-15) of ND using human lung cancer cells (A-549) experiment, the selected sub-fractions of the chloroform extract demonstrated a significantly activity in reduced the cell viability of A-549 cells, through alternated the cancer cell structures and arrangement in a concentration-dependent manner.
In a classification of the effect of each individual subfraction, researchers found that ND-10 fraction induces the greatest cytotoxicity in the lowest dose compared to other fractions with ND-1 does not cause any cytotoxicity even at higher concentrations.
In comparison to other cancer cell lines, human lung cancer cells (A-549) were found to be more sensitive to the application of the extracts.
Further differentiation of the Nepeta cataria L. anti-cancer treatment effect recorded in the Chinese Pharmacopoeia of version 2015 and belongs to one of the Traditional Chinese medicine (TCM). Microfluidic chip technology, researchers at the joint study led by the Liaoning University of Traditional Chinese Medicine conducted a study based on total flavonoid extracted from Nepeta cataria L. (TFS) on risk of human lung cancer cell line A549 using the microfluidic device and Flow Cytometry assays, suggested that the bioactive chemicals exert a significant activity in inhibited cancer cell proliferation and tumor progression and invasion through mRNA expression of MicroRNA-126 (miR-126) which plays an important role involved in post-transcriptional regulation of gene expression in inhibition of human cancer progression, regulating apoptosis of cancer cells.
Additionally, the anti lung cancer expression was attributed to ameliorate the vascular endothelial growth factor (VEGF), a potent angiogenic factor with function to trigger development of new blood vessel to supply nutrients and oxygen to ignite cancer cell proliferation and inhibited the expression of the PI3K signaling pathway which is correlated to the cancer aggression and invasive malignancy.
Researchers also indicated that according to the Flow Cytometry assay, the phytochemicals also exhibit the expression of PTEN (phosphatase and tensin homolog deleted on chromosome 10) PTEN gene in initiated tumor suppressible activity through expression PI3K-AKT pathway in induced cell cycle arrest or apoptosis in human cancer cells
Dr. Jiaxin Fan, the lead author, after taking into account other confounders said, " Taking all these results into consideration we can draw a conclusion that TFS may be used as a novel therapeutic agent for NSCLC in the near future".
The information findings postulated that herbal catnip with abundant bioactive compounds may be considered as a functional food in reduced risk and treatment of human lung cancer, depending on further differentiation.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Anticancer Activity of Chloroform Extract and Sub-fractions of Nepeta deflersiana on Human Breast and Lung Cancer Cells: An In vitro Cytotoxicity Assessment by Al-Oqail MM1, Al-Sheddi ES1, Siddiqui MA2, Musarrat J2, Al-Khedhairy AA2, Farshori NN1.(PubMed)
(2) Mechanism of modulation through PI3K-AKT pathway about Nepeta cataria L.’s extract in non-small cell lung cancer by Jiaxin Fan,#1 Yongrui Bao,#1,2,3,4 Xiansheng Meng,1,2,3,4 Shuai Wang,1,2,3,4 Tianjiao Li,1,2,3,4 Xin Chang,1 Guanlin Yang,1 and Tao Bo4(PMC)
Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, used in herbal medicine as insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, colds and flu, skin irritations stimulate sweating, promote menstruation, etc..
Ingredients
Terpenoid nepetalactone, α-Pinene, β-Pinene, Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone, Nepetalactone, etc..
Lung cancer is a medical condition characterized by irregular cell growth in the tissues of the lung. At the later stage, the cancerous cell may invade other healthy tissues and organs a distance away from the original site.
According to statistics, In 2015, approximately 26,600 Canadians will be diagnosed with lung cancer and 20,900 will die of it.
According to the investigation of the anti-cancer effect of extracts isolated from catnip containing sub-fractions (ND-1-ND-15) of ND using human lung cancer cells (A-549) experiment, the selected sub-fractions of the chloroform extract demonstrated a significantly activity in reduced the cell viability of A-549 cells, through alternated the cancer cell structures and arrangement in a concentration-dependent manner.
In a classification of the effect of each individual subfraction, researchers found that ND-10 fraction induces the greatest cytotoxicity in the lowest dose compared to other fractions with ND-1 does not cause any cytotoxicity even at higher concentrations.
In comparison to other cancer cell lines, human lung cancer cells (A-549) were found to be more sensitive to the application of the extracts.
Further differentiation of the Nepeta cataria L. anti-cancer treatment effect recorded in the Chinese Pharmacopoeia of version 2015 and belongs to one of the Traditional Chinese medicine (TCM). Microfluidic chip technology, researchers at the joint study led by the Liaoning University of Traditional Chinese Medicine conducted a study based on total flavonoid extracted from Nepeta cataria L. (TFS) on risk of human lung cancer cell line A549 using the microfluidic device and Flow Cytometry assays, suggested that the bioactive chemicals exert a significant activity in inhibited cancer cell proliferation and tumor progression and invasion through mRNA expression of MicroRNA-126 (miR-126) which plays an important role involved in post-transcriptional regulation of gene expression in inhibition of human cancer progression, regulating apoptosis of cancer cells.
Additionally, the anti lung cancer expression was attributed to ameliorate the vascular endothelial growth factor (VEGF), a potent angiogenic factor with function to trigger development of new blood vessel to supply nutrients and oxygen to ignite cancer cell proliferation and inhibited the expression of the PI3K signaling pathway which is correlated to the cancer aggression and invasive malignancy.
Researchers also indicated that according to the Flow Cytometry assay, the phytochemicals also exhibit the expression of PTEN (phosphatase and tensin homolog deleted on chromosome 10) PTEN gene in initiated tumor suppressible activity through expression PI3K-AKT pathway in induced cell cycle arrest or apoptosis in human cancer cells
Dr. Jiaxin Fan, the lead author, after taking into account other confounders said, " Taking all these results into consideration we can draw a conclusion that TFS may be used as a novel therapeutic agent for NSCLC in the near future".
The information findings postulated that herbal catnip with abundant bioactive compounds may be considered as a functional food in reduced risk and treatment of human lung cancer, depending on further differentiation.
For More information on yoga lessons tailor to a complete well being for women, please visit: YOGA FOR WOMEN
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Anticancer Activity of Chloroform Extract and Sub-fractions of Nepeta deflersiana on Human Breast and Lung Cancer Cells: An In vitro Cytotoxicity Assessment by Al-Oqail MM1, Al-Sheddi ES1, Siddiqui MA2, Musarrat J2, Al-Khedhairy AA2, Farshori NN1.(PubMed)
(2) Mechanism of modulation through PI3K-AKT pathway about Nepeta cataria L.’s extract in non-small cell lung cancer by Jiaxin Fan,#1 Yongrui Bao,#1,2,3,4 Xiansheng Meng,1,2,3,4 Shuai Wang,1,2,3,4 Tianjiao Li,1,2,3,4 Xin Chang,1 Guanlin Yang,1 and Tao Bo4(PMC)
Herbal Ashwagandha Inhibits Glioma In Vivo
A glioma is a type of tumor that starts in the glial cells of the brain or the spine.
Glioma cells can be classified into
* Astrocytomas is a type of brain cancer originated in a particular kind of glial cell, star-shaped brain cells in the cerebrum called astrocytes.
* Ependymomas, is a type of cancer that grows in your brain or any part of the spine, including your neck and upper and lower back.
* Oligodendrogliomas are a type of glioma that starts in glial cells called oligodendrocytes.
Primary glioblastoma is one of the most aggressive cancers that begins within the brain. Cancer may arise as a Grade IV tumor with no evidence.
According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.
In the US, the median age of glioblastoma diagnosed is 64 years and the incidence of the disease onset is 1.6 times higher in males compared to females.
Furthermore, the condition is 2 times higher in Caucasians compared to Africans and Afro-Americans.
Because of the rapid growth, patients diagnosed with primary glioblastoma experience sudden brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.
Conventionally, radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.
The causes of glioblastoma are not identified. However, the increase in age and genetic preposition are the 2 most common risk factors found in patients with the disease.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for inhibition of brain tumor researchers examined the combined active ingredients of Chinese (Helicteres angustifolia) and Indian (Withaniasomnifera) ginsengs effects on glial differentiation potentials.
Based on the tested analysis, the novel combination of Cuc and Wi-N, CucWi-N, showed a significant activity to protect the neurons cells against oxidative stress-induced a decrease in DNA damage.
In rat glioblastoma cells, CucWi-N exerted the glial differentiation potential and induced differentiation phenotype.
Proteins associated with the neuron growth and development and a key role in glial differentiation. such as GAP43, MAP2, and GFAP were exhibited by the injection of the combination.
Based on the findings, researchers said, "These data demonstrate anti-stress and glial differentiation potential of CucWi-N (a novel combination of Cuc and Wi-N) that could be recruited in nutraceutical and pharmaceutical avenues and hence warrant further evaluation and mechanistic studies.".
Taken altogether, Ashwagandha may be considered a functional herb that reduces the risk of brain tumors, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Stress and Glial Differentiation Effects of a Novel Combination of Cucurbitacin B and Withanone (CucWi-N): Experimental Evidence by Garg S1,2, Kaul SC1, Wadhwa R. (PubMed)
Glioma cells can be classified into
* Astrocytomas is a type of brain cancer originated in a particular kind of glial cell, star-shaped brain cells in the cerebrum called astrocytes.
* Ependymomas, is a type of cancer that grows in your brain or any part of the spine, including your neck and upper and lower back.
* Oligodendrogliomas are a type of glioma that starts in glial cells called oligodendrocytes.
Primary glioblastoma is one of the most aggressive cancers that begins within the brain. Cancer may arise as a Grade IV tumor with no evidence.
According to the statistic, the median survival time of primary glioblastoma is approximately 3 months without medical treatment. Glioblastomas represent about 15% of all primary brain tumors.
In the US, the median age of glioblastoma diagnosed is 64 years and the incidence of the disease onset is 1.6 times higher in males compared to females.
Furthermore, the condition is 2 times higher in Caucasians compared to Africans and Afro-Americans.
Because of the rapid growth, patients diagnosed with primary glioblastoma experience sudden brain swelling and increased brain pressure, leading to symptoms of nausea, vomiting, and severe headaches and localized symptoms depending on the location of the tumor.
Conventionally, radiation and chemotherapy are the most common forms of treatment for patients with glioblastoma particularly, in a tumor that cannot be removed with surgery.
The causes of glioblastoma are not identified. However, the increase in age and genetic preposition are the 2 most common risk factors found in patients with the disease.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for inhibition of brain tumor researchers examined the combined active ingredients of Chinese (Helicteres angustifolia) and Indian (Withaniasomnifera) ginsengs effects on glial differentiation potentials.
Based on the tested analysis, the novel combination of Cuc and Wi-N, CucWi-N, showed a significant activity to protect the neurons cells against oxidative stress-induced a decrease in DNA damage.
In rat glioblastoma cells, CucWi-N exerted the glial differentiation potential and induced differentiation phenotype.
Proteins associated with the neuron growth and development and a key role in glial differentiation. such as GAP43, MAP2, and GFAP were exhibited by the injection of the combination.
Based on the findings, researchers said, "These data demonstrate anti-stress and glial differentiation potential of CucWi-N (a novel combination of Cuc and Wi-N) that could be recruited in nutraceutical and pharmaceutical avenues and hence warrant further evaluation and mechanistic studies.".
Taken altogether, Ashwagandha may be considered a functional herb that reduces the risk of brain tumors, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-Stress and Glial Differentiation Effects of a Novel Combination of Cucurbitacin B and Withanone (CucWi-N): Experimental Evidence by Garg S1,2, Kaul SC1, Wadhwa R. (PubMed)
Herbal Artichoke, the Best Antioxidants Functional Food, Researchers Reveal
Scientists may have found a herbal remedy processed significant antioxidant activity against the onset and progression of oxidative stress-related diseases, according to studies.
Oxidative stress-related conditions are the class of diseases associated with cellular damage, including the alternation of cell DNA, and damage of lipid and protein.
The list of chronic diseases caused by cell oxidation is very long, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
The most common causes of oxidative stress are overexpression of free radicals in the induction of a chain reaction.
Due to the unstable nature of free radicals with unpaired electrons in the outer ring, free radicals are ready to donate or intercept the electrons from other atoms, leading to a chain reaction that can not be stopped until the outring electron are either paired or inhibited by antioxidants.
Contrast to the general belief, the damage caused by free radicals are overly exaggerated, under normal condition, free radicals produced by the internal or external source are needed by our body on cellular responses and immune function.
However, overexpression of free radicals also known as oxidative stress can be a danger to our health.
Oxidative stress can be acute or chronic. Acute oxidative stress caused by suddenly burst of free radical due to stress or external sources, in most cases can be inhibited by increasing antioxidant enzymes by the lung.
Chronic oxidative stress is caused by the unbalanced ratio of free radicals and antioxidant enzymes produced by our body. The condition is either caused by oner expression of free radicals or depletion of antioxidant enzymes or both.
There are many risk factors that cause oxidative stress. However, in the concerns of the prevalence of chronic diseases associated with the Western diet, some researchers suggested that the link of the oxidative diseases in the Western world may be resulted by the promotion of the Western diet over the past few decades.
Dr. Ildiko Erdelyi, the lead scientist said, "A Western-style diet (WD), defined by high-fat, low-calcium, and vitamin D content, is associated with increased risk of human colorectal cancer. Understanding molecular mechanisms altered by the WD is crucial to develop preventive and therapeutic strategies".
And, "consumption of a WD interferes with networks of related biological response pathways involving colonic lipid metabolism, oxidative stress, and the immune response".
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Scientists on finding a natural ingredient for the treatment of oxidative stress-related diseases examined the antioxidant activity of artichoke in the rat model.
Artichoke extracts showed good efficiency in the inhibition in vitro of LDL oxidation. Injection of artichoke extracts also increased the levels of antioxidant glutathione peroxidase against oxidative damage in the tested subjects compared to the control group.
Injection of artichoke extracts also inhibited the expression of a protein oxidation biomarker (2-Aminoadipic semialdehyde) compared to the control group.
In order to reveal more information of artichoke antioxidant activity, researchers examined the phenolic compound content and composition and the antioxidant activity of leaf parts [blades (SLB), petioles and midribs (SPM)] from various Greek artichoke genotypes.
The leaf blades of most of the genotypes having a high content of flavonoids (mainly luteolin glycoside derivatives), which ranged between 49 and 78% of total phenolic compounds (TPC).
Petioles and midribs phenolic acids (mainly hydroxycinnamic acid derivatives) were the main phenolic compounds, ranging between 64 and 76% of TPC,
The antioxidant activity of blades was significantly higher than that of petiole and midribs for all the genotypes according to the tested assays.
The results of antioxidant differentiation suggested that artichoke leaves (blades, petioles, and midribs) show different bioactive compound profiles in stimulating the different levels of antioxidant properties.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of oxidative stress-related diseases through its antioxidant activity, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) In vitro antioxidant activities of edible artichoke (Cynara scolymus L.) and effect on biomarkers of antioxidants in rats by Jiménez-Escrig A1, Dragsted LO, Daneshvar B, Pulido R, Saura-Calixto F. (PubMed)
(2) Leaf parts from Greek artichoke genotypes as a good source of bioactive compounds and antioxidants by Petropoulos SA1, Pereira C, Barros L, Ferreira ICFR. (PubMed)
(3) Western-Style Diets Induce Oxidative Stress and Dysregulate Immune Responses in the Colon in a Mouse Model of Sporadic Colon Cancer by Ildiko Erdelyi,4 Natasha Levenkova,5 Elaine Y. Lin,8 John T. Pinto,9 Martin Lipkin,4Fred W. Quimby,6 and Peter R. Holt. (PMC)
Oxidative stress-related conditions are the class of diseases associated with cellular damage, including the alternation of cell DNA, and damage of lipid and protein.
The list of chronic diseases caused by cell oxidation is very long, including atherosclerosis, cancer, diabetics, rheumatoid arthritis, post-ischemic perfusion injury, myocardial infarction, cardiovascular diseases, chronic inflammation, stroke.
The most common causes of oxidative stress are overexpression of free radicals in the induction of a chain reaction.
Due to the unstable nature of free radicals with unpaired electrons in the outer ring, free radicals are ready to donate or intercept the electrons from other atoms, leading to a chain reaction that can not be stopped until the outring electron are either paired or inhibited by antioxidants.
Contrast to the general belief, the damage caused by free radicals are overly exaggerated, under normal condition, free radicals produced by the internal or external source are needed by our body on cellular responses and immune function.
However, overexpression of free radicals also known as oxidative stress can be a danger to our health.
Oxidative stress can be acute or chronic. Acute oxidative stress caused by suddenly burst of free radical due to stress or external sources, in most cases can be inhibited by increasing antioxidant enzymes by the lung.
Chronic oxidative stress is caused by the unbalanced ratio of free radicals and antioxidant enzymes produced by our body. The condition is either caused by oner expression of free radicals or depletion of antioxidant enzymes or both.
There are many risk factors that cause oxidative stress. However, in the concerns of the prevalence of chronic diseases associated with the Western diet, some researchers suggested that the link of the oxidative diseases in the Western world may be resulted by the promotion of the Western diet over the past few decades.
Dr. Ildiko Erdelyi, the lead scientist said, "A Western-style diet (WD), defined by high-fat, low-calcium, and vitamin D content, is associated with increased risk of human colorectal cancer. Understanding molecular mechanisms altered by the WD is crucial to develop preventive and therapeutic strategies".
And, "consumption of a WD interferes with networks of related biological response pathways involving colonic lipid metabolism, oxidative stress, and the immune response".
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Scientists on finding a natural ingredient for the treatment of oxidative stress-related diseases examined the antioxidant activity of artichoke in the rat model.
Artichoke extracts showed good efficiency in the inhibition in vitro of LDL oxidation. Injection of artichoke extracts also increased the levels of antioxidant glutathione peroxidase against oxidative damage in the tested subjects compared to the control group.
Injection of artichoke extracts also inhibited the expression of a protein oxidation biomarker (2-Aminoadipic semialdehyde) compared to the control group.
In order to reveal more information of artichoke antioxidant activity, researchers examined the phenolic compound content and composition and the antioxidant activity of leaf parts [blades (SLB), petioles and midribs (SPM)] from various Greek artichoke genotypes.
The leaf blades of most of the genotypes having a high content of flavonoids (mainly luteolin glycoside derivatives), which ranged between 49 and 78% of total phenolic compounds (TPC).
Petioles and midribs phenolic acids (mainly hydroxycinnamic acid derivatives) were the main phenolic compounds, ranging between 64 and 76% of TPC,
The antioxidant activity of blades was significantly higher than that of petiole and midribs for all the genotypes according to the tested assays.
The results of antioxidant differentiation suggested that artichoke leaves (blades, petioles, and midribs) show different bioactive compound profiles in stimulating the different levels of antioxidant properties.
Taken altogether, artichoke may be considered a functional remedy for the prevention and treatment of oxidative stress-related diseases through its antioxidant activity, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) In vitro antioxidant activities of edible artichoke (Cynara scolymus L.) and effect on biomarkers of antioxidants in rats by Jiménez-Escrig A1, Dragsted LO, Daneshvar B, Pulido R, Saura-Calixto F. (PubMed)
(2) Leaf parts from Greek artichoke genotypes as a good source of bioactive compounds and antioxidants by Petropoulos SA1, Pereira C, Barros L, Ferreira ICFR. (PubMed)
(3) Western-Style Diets Induce Oxidative Stress and Dysregulate Immune Responses in the Colon in a Mouse Model of Sporadic Colon Cancer by Ildiko Erdelyi,4 Natasha Levenkova,5 Elaine Y. Lin,8 John T. Pinto,9 Martin Lipkin,4Fred W. Quimby,6 and Peter R. Holt. (PMC)
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