Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere. It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
Airway inflammation is the inflammation of the airway as a result of other conditions include asthma, chronic bronchitis, bronchiectasis, and cystic fibrosis.
The Ingredients
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.
The benefits
Petasites japonicus (Pj), the giant butterbur has been used in traditional Oriental medicine for treating asthma, oxidant stress, and gastric ulcer. It extracts has exerted its suppressive properties for the pathogenesis of airway inflammation and may be considered a potent agent for the treatment of asthma. Other in the study of Petasites extract Ze 339 (PET) of herbal Petasites hybridus (butterbur) showed to inhibit leukotriene activity, reduce allergic airway inflammation and AHR by inhibiting the production of the Th2 cytokines IL-4 and IL-5, and RANTES.
Ovarian Cysts And PCOS Elimination
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Side effects
1. Butterbur may be liver-toxic to the liver and cause cancer due to the presence of pyrrolizidine alkaloids(a)
2. If you are pregnant please do not use Butterbur without the permission of the related special field specialist
3. Allergic effect on certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
References
(1) Suppressive effect of Petasites japonicus extract on ovalbumin-induced airway inflammation in an asthmatic mouse model by Lee JS, Yang EJ, Yun CY, Kim DH, Kim IS.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
Monday, February 3, 2020
Herbal Therapy: Cayenne, the Natural Whole Herb for Antimicrobial Infection
Whole food(herbal medicine) used as medical treatment, linking health benefits in prevention, management and treatment of diseases has induced many interests in today renowned scientists.
But many researchers have raised the question of herbal quality, because geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experienced herbalists.
Cayenne may be the next antimntimicrobial natural whole foods used for the prevention and treatment of infection, inflammation and the common cold.
According to the joint study led by the Universidad Michoacana de San Nicolás de Hidalgo, cayenne exhibited a broad-spectrum antimicrobial action, through its' immunomodulatory roles of mammal β-defensins(antimicrobial peptides) in regulated inflammation and activated the immune system.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
Thionins, a chemical compound found in cayenne is considered as antimicrobial peptides (AMPs), which regulate plant defense system against pathogens. such as Candida species, with IC50 ranging from 10 to 40 μg.mL(-1).
The chemical compound also exhibited anti antimicrobial effect through its antioxidant activity against oxidative stresses. In bacteria and yeasts induced infection and inflammatory diseases, it exhibited toxicity and induced changes in the membranes of all yeast strains, leading to their permeabilization.
Dr. Diz MS, the lead author in the study peptides from chili pepper seeds, said, " F1(peptides from chili pepper (Capsicum annuum L.) seeds) fraction exhibited strong fungicidal activity against Candida albicans, Saccharomyces cerevisiae and Schizosaccharomyces pombe and also promoted several morphological changes to C. Albicans".
In some yeast species, peptides isolated from cayenne also inhibited the growth of yeasts Saccharomyces cerevisiae, Candida albicans, Candida parapsilosis, Candida tropicalis, Pichia membranifaciens,
Intake of cayenne may improve the immunomodulatory activity in the body against microbial organisms induced infection and inflammation, but quantity intake should only be given by herbalist for prevention of overdoses' toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
(2) Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species by Taveira GB1, Carvalho AO2, Rodrigues R3, Trindade FG4, Da Cunha M5, Gomes VM6(PubMed)
(3) Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts by Taveira GB1, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM.(PubMed)
(4) Antimicrobial peptides from chili pepper seeds causes yeast plasma membrane permeabilization and inhibits the acidification of the medium by yeast cells by Diz MS1, Carvalho AO, Rodrigues R, Neves-Ferreira AG, Da Cunha M, Alves EW, Okorokova-Façanha AL, Oliveira MA, Perales J, Machado OL, Gomes VM.(PubMed)
But many researchers have raised the question of herbal quality, because geographic differences, time of grown and harvest, etc. may affect their's potency. I do believe, these questions can only be answered by experienced herbalists.
Cayenne may be the next antimntimicrobial natural whole foods used for the prevention and treatment of infection, inflammation and the common cold.
According to the joint study led by the Universidad Michoacana de San Nicolás de Hidalgo, cayenne exhibited a broad-spectrum antimicrobial action, through its' immunomodulatory roles of mammal β-defensins(antimicrobial peptides) in regulated inflammation and activated the immune system.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
Thionins, a chemical compound found in cayenne is considered as antimicrobial peptides (AMPs), which regulate plant defense system against pathogens. such as Candida species, with IC50 ranging from 10 to 40 μg.mL(-1).
The chemical compound also exhibited anti antimicrobial effect through its antioxidant activity against oxidative stresses. In bacteria and yeasts induced infection and inflammatory diseases, it exhibited toxicity and induced changes in the membranes of all yeast strains, leading to their permeabilization.
Dr. Diz MS, the lead author in the study peptides from chili pepper seeds, said, " F1(peptides from chili pepper (Capsicum annuum L.) seeds) fraction exhibited strong fungicidal activity against Candida albicans, Saccharomyces cerevisiae and Schizosaccharomyces pombe and also promoted several morphological changes to C. Albicans".
In some yeast species, peptides isolated from cayenne also inhibited the growth of yeasts Saccharomyces cerevisiae, Candida albicans, Candida parapsilosis, Candida tropicalis, Pichia membranifaciens,
Intake of cayenne may improve the immunomodulatory activity in the body against microbial organisms induced infection and inflammation, but quantity intake should only be given by herbalist for prevention of overdoses' toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
(2) Thionin-like peptide from Capsicum annuum fruits: mechanism of action and synergism with fluconazole against Candida species by Taveira GB1, Carvalho AO2, Rodrigues R3, Trindade FG4, Da Cunha M5, Gomes VM6(PubMed)
(3) Thionin-like peptides from Capsicum annuum fruits with high activity against human pathogenic bacteria and yeasts by Taveira GB1, Mathias LS, da Motta OV, Machado OL, Rodrigues R, Carvalho AO, Teixeira-Ferreira A, Perales J, Vasconcelos IM, Gomes VM.(PubMed)
(4) Antimicrobial peptides from chili pepper seeds causes yeast plasma membrane permeabilization and inhibits the acidification of the medium by yeast cells by Diz MS1, Carvalho AO, Rodrigues R, Neves-Ferreira AG, Da Cunha M, Alves EW, Okorokova-Façanha AL, Oliveira MA, Perales J, Machado OL, Gomes VM.(PubMed)
Sunday, February 2, 2020
Herbal cayenne Normalizes the Levels of High Blood Cholesterol with No Side Effects, According to Studies
Herbal Cayenne processed a high amount of bioactive compound capsaicinoids that may have a strong and potential effect in reducing levels of high blood cholesterol, according to studies.
Hyperlipidemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.
Dr. Joan Carles Escolà-Gil and colleagues in the concern about the Western diet pattern in risk of high blood cholesterol wrote, "The HFHC diet caused a significant increase in plasma cholesterol, HDL cholesterol, and liver cholesterol and enhanced macrophage-derived [3H]cholesterol flux to feces by 3- to 4-fold, (in tested mice)".
And, " The HFHC diet caused 1.4- and 3-fold increases in [3H]cholesterol efflux to plasma and HDL-derived [3H]tracer fecal excretion".
The results strongly indicated there is a clinical significance of a high-fat diet in the increased substantially risk of high blood cholesterol.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
The herbal medicine has been used in traditional medicine to increases metabolism, enhance the circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.
Researchers on finding herbal medicine for the treatment of high blood cholesterol examined the antihyperlipidemic effects of capsaicinoids, the active compounds in chili pepper.
Hamsters selected to the study were divided into five groups and fed a high-cholesterol diet containing 0 % (CON), 0.010 % (LD), 0.015 % (MD), 0.020 % (HD), and 0.030 % (VD) capsaicinoids, respectively, for 6 weeks.
Capsaicinoids reduced plasma total cholesterol, non-high-density lipoprotein, and triacylglycerols without affecting the levels of high-density lipoprotein.
Dietary capsaicinoids increased the fecal excretion of total acidic sterols possibly associated with an enzyme which oxidizes cholesterol and inhibited the liver X receptor alpha which was found to raised HDL-cholesterol and increased liver triglycerides in a wild-type mice study.
Furthermore, capsaicinoids not only decreased cholesterol absorption but also improved the levels of expression of COX-2 associated with the accumulation of lipids in circulation and liver, and lipid peroxidation in case of deficiency.
Dr. Liang YT, the lead scientist, after taking into account co and confounders wrote, "Capsaicinoids were beneficial in improving lipoprotein profile and aortic function in hamsters fed a high-cholesterol diet".
Moreover, in female ovariectomized Sprague-Dawley rats, the sham group and OVX control group were fed with high-cholesterol diets, whereas the treatment group (control diet containing 0.01% capsaicinoids) was fed with high-cholesterol plus 0.01% capsaicinoids diet for 21 days.
Injection of capsaicinoids significantly decreased the body weight gain, plasma total cholesterol, LDL cholesterol, and triacylglycerol without affecting the high-density lipoprotein cholesterol in the OVX rats.
These changes in plasma lipoprotein profile were accompanied by a greater excretion of total bile acid in feces and small intestinal contents.
The efficacy of the compound in the inhibition of high blood cholesterol was attributed to the significantly enhanced the expressions of hepatic cholesterol 7α-hydroxylase, an enzyme and receptor potential vanilloid type-1 associated with cholesterol oxidation.
Dr. Zhang L, the lead researchers wrote in the final report, "The hypocholesterolemic activity of capsaicinoids is caused by the stimulating conversion of cholesterol to bile acids by upregulation of cholesterol 7α-hydroxylase expression and the increase in fecal total bile acid excretion".
Taken altogether, herbal cayenne processed major bioactive ingredient capsaicinoids may be considered a function fruit for the prevention and treatment of high blood cholesterol, pending to the
larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters by Liang YT1, Tian XY, Chen JN, Peng C, Ma KY, Zuo Y, Jiao R, Lu Y, Huang Y, Chen ZY.(PubMed)
(2) The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis by Zhang L1, Fang G, Zheng L, Chen Z, Liu X.(PubMed)
(3) Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats by Zhang L1, Zhou M, Fang G, Tang Y, Chen Z, Liu X.(PubMed)
Hyperlipidemia is a condition of abnormally high levels of cholesterol in the bloodstream.
Cholesterol is a waxy substance that is produced either by the liver or injected from animal food sources.
Cholesterol found in our body is needed for our body to build cell walls, hormones, and vitamin D, and create bile salts that aid digestion. However, too much of them, in most cases due to the intake of animal protein can cause plaques built up on the arterial wall, the major cause of heart disease and stroke.
More precisely, if levels of low-density lipoprotein are high compared to high-density lipoprotein which returns the accessed cholesterol back to the liver, you have high blood cholesterol.
In other words, healthy blood cholesterol is any level with either less than or equal to 4 (low-density lipoprotein/ 1 (high-density lipoprotein).
According to the statistics, in 2015-2016, by age and gender, a total of 12.4 percent of adults aged 20 years and over had high cholesterol in the United States.
Although there are many risk factors such as obesity, large waist circumference, physically inactive, smoking and diabetes associated with the onset of high blood cholesterol, researchers suggested that a poor diet with rich in saturated and trans fat, processed foods is the major cause of high blood cholesterol in the Western world.
Dr. Joan Carles Escolà-Gil and colleagues in the concern about the Western diet pattern in risk of high blood cholesterol wrote, "The HFHC diet caused a significant increase in plasma cholesterol, HDL cholesterol, and liver cholesterol and enhanced macrophage-derived [3H]cholesterol flux to feces by 3- to 4-fold, (in tested mice)".
And, " The HFHC diet caused 1.4- and 3-fold increases in [3H]cholesterol efflux to plasma and HDL-derived [3H]tracer fecal excretion".
The results strongly indicated there is a clinical significance of a high-fat diet in the increased substantially risk of high blood cholesterol.
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions.
The herbal medicine has been used in traditional medicine to increases metabolism, enhance the circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.
The chemical constituents of Cayenne include capsaicin, capsacutin oil, solaine, xanthenes, oleic acid, palmitic acid, etc.
Researchers on finding herbal medicine for the treatment of high blood cholesterol examined the antihyperlipidemic effects of capsaicinoids, the active compounds in chili pepper.
Hamsters selected to the study were divided into five groups and fed a high-cholesterol diet containing 0 % (CON), 0.010 % (LD), 0.015 % (MD), 0.020 % (HD), and 0.030 % (VD) capsaicinoids, respectively, for 6 weeks.
Capsaicinoids reduced plasma total cholesterol, non-high-density lipoprotein, and triacylglycerols without affecting the levels of high-density lipoprotein.
Dietary capsaicinoids increased the fecal excretion of total acidic sterols possibly associated with an enzyme which oxidizes cholesterol and inhibited the liver X receptor alpha which was found to raised HDL-cholesterol and increased liver triglycerides in a wild-type mice study.
Furthermore, capsaicinoids not only decreased cholesterol absorption but also improved the levels of expression of COX-2 associated with the accumulation of lipids in circulation and liver, and lipid peroxidation in case of deficiency.
Dr. Liang YT, the lead scientist, after taking into account co and confounders wrote, "Capsaicinoids were beneficial in improving lipoprotein profile and aortic function in hamsters fed a high-cholesterol diet".
Moreover, in female ovariectomized Sprague-Dawley rats, the sham group and OVX control group were fed with high-cholesterol diets, whereas the treatment group (control diet containing 0.01% capsaicinoids) was fed with high-cholesterol plus 0.01% capsaicinoids diet for 21 days.
Injection of capsaicinoids significantly decreased the body weight gain, plasma total cholesterol, LDL cholesterol, and triacylglycerol without affecting the high-density lipoprotein cholesterol in the OVX rats.
These changes in plasma lipoprotein profile were accompanied by a greater excretion of total bile acid in feces and small intestinal contents.
The efficacy of the compound in the inhibition of high blood cholesterol was attributed to the significantly enhanced the expressions of hepatic cholesterol 7α-hydroxylase, an enzyme and receptor potential vanilloid type-1 associated with cholesterol oxidation.
Dr. Zhang L, the lead researchers wrote in the final report, "The hypocholesterolemic activity of capsaicinoids is caused by the stimulating conversion of cholesterol to bile acids by upregulation of cholesterol 7α-hydroxylase expression and the increase in fecal total bile acid excretion".
Taken altogether, herbal cayenne processed major bioactive ingredient capsaicinoids may be considered a function fruit for the prevention and treatment of high blood cholesterol, pending to the
larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Capsaicinoids lower plasma cholesterol and improve endothelial function in hamsters by Liang YT1, Tian XY, Chen JN, Peng C, Ma KY, Zuo Y, Jiao R, Lu Y, Huang Y, Chen ZY.(PubMed)
(2) The hypocholesterolemic effect of capsaicinoids in ovariectomized rats fed with a cholesterol-free diet was mediated by inhibition of hepatic cholesterol synthesis by Zhang L1, Fang G, Zheng L, Chen Z, Liu X.(PubMed)
(3) Hypocholesterolemic effect of capsaicinoids by increased bile acids excretion in ovariectomized rats by Zhang L1, Zhou M, Fang G, Tang Y, Chen Z, Liu X.(PubMed)
Chaste Tree Berry in Reduced Risk and Treatment of Colon Cancer
Vitex agnus-castus fruit is found to process an anti irregular cell growth, the early stage of cancer development in colon, a university study suggested.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Colon cancer is a medical condition of the abnormal proliferation of cells in the large intestine.
According to the Tokyo University of Pharmacy & Life Sciences, treatment with chaste tree berry induced apoptosis of cancer cells not by the presence of antioxidants but an expression of antibody gene HO-1 in regulating oxidative stress.
Dr. Imai M, the lead researcher said. "Vitex treatment activates a pathway associated with HO-1 gene activation, resulting in the induction of apoptosis in COLO 201, (the colon cancer cell line)".
Additionally, in a novel strategy with biological approach for synthesis of silver nanoparticles (AgNPs), a toxic substance, using sodium para-hydroxybenzoate tetrahydrate (SPHT) isolated from Vitex negundo leaves, treatment of sodium para-hydroxybenzoate tetrahydrate (SPHT) improved the hydroxyl and carboxylic functional groups mediators in exhibited a stronger ability towards synthesis of AgNPs which indicated the apoptotic effect on human colon cancer cell lines.
The study also insisted that the extract displays an anti colon cancer activity confirmed by colorimetric assay, annexin V/Dead Cell Apoptosis and cell cycle analysis.
Furthermore, casticin, one of the major components of the fruits of chaste tree, showed a significantly induced apoptosis effect in of HT-29, HCT-116, SW480 and Caco-2 cells, reduced accumulation of reactive oxygen species (ROS) and increased the protein levels in regulation of cancer cell apoptosis and B-cell lymphoma activation of cell death of HT-29 cells, a colon cancer cell line.
Collectively, casticin also promoted Cell Death in cell division with the same mechanisms in other cancer cell lines, including HCT-116, SW480 and Caco-2 cells.
Taking together, chaste tree berry may be the next therapeutic treatment for reduced risk and treatment of colon cancer, but the injection of large quantity should only be prescribed by related field specialists.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance by Imai M1, Kikuchi H, Denda T, Ohyama K, Hirobe C, Toyoda H.(PubMed)
(2) Synthesis and characterization of silver nanoparticles using crystal compound of sodium para-hydroxybenzoate tetrahydrate isolated from Vitex negundo. L leaves and its apoptotic effect on human colon cancer cell lines by Durai P1, Chinnasamy A2, Gajendran B1, Ramar M1, Pappu S3, Kasivelu G4, Thirunavukkarasu A5.(PubMed)
(3) Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells by Qu L1, Liu FX1, Cao XC2, Xiao Q2, Yang X2, Ren KQ2.(PubMed)
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Colon cancer is a medical condition of the abnormal proliferation of cells in the large intestine.
According to the Tokyo University of Pharmacy & Life Sciences, treatment with chaste tree berry induced apoptosis of cancer cells not by the presence of antioxidants but an expression of antibody gene HO-1 in regulating oxidative stress.
Dr. Imai M, the lead researcher said. "Vitex treatment activates a pathway associated with HO-1 gene activation, resulting in the induction of apoptosis in COLO 201, (the colon cancer cell line)".
Additionally, in a novel strategy with biological approach for synthesis of silver nanoparticles (AgNPs), a toxic substance, using sodium para-hydroxybenzoate tetrahydrate (SPHT) isolated from Vitex negundo leaves, treatment of sodium para-hydroxybenzoate tetrahydrate (SPHT) improved the hydroxyl and carboxylic functional groups mediators in exhibited a stronger ability towards synthesis of AgNPs which indicated the apoptotic effect on human colon cancer cell lines.
The study also insisted that the extract displays an anti colon cancer activity confirmed by colorimetric assay, annexin V/Dead Cell Apoptosis and cell cycle analysis.
Furthermore, casticin, one of the major components of the fruits of chaste tree, showed a significantly induced apoptosis effect in of HT-29, HCT-116, SW480 and Caco-2 cells, reduced accumulation of reactive oxygen species (ROS) and increased the protein levels in regulation of cancer cell apoptosis and B-cell lymphoma activation of cell death of HT-29 cells, a colon cancer cell line.
Collectively, casticin also promoted Cell Death in cell division with the same mechanisms in other cancer cell lines, including HCT-116, SW480 and Caco-2 cells.
Taking together, chaste tree berry may be the next therapeutic treatment for reduced risk and treatment of colon cancer, but the injection of large quantity should only be prescribed by related field specialists.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance by Imai M1, Kikuchi H, Denda T, Ohyama K, Hirobe C, Toyoda H.(PubMed)
(2) Synthesis and characterization of silver nanoparticles using crystal compound of sodium para-hydroxybenzoate tetrahydrate isolated from Vitex negundo. L leaves and its apoptotic effect on human colon cancer cell lines by Durai P1, Chinnasamy A2, Gajendran B1, Ramar M1, Pappu S3, Kasivelu G4, Thirunavukkarasu A5.(PubMed)
(3) Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells by Qu L1, Liu FX1, Cao XC2, Xiao Q2, Yang X2, Ren KQ2.(PubMed)
Cat's claw, The best Whole Herb Medicine for Prevention and Treatment of Inflammatory diseases
Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae, used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
Inflammatory diseases are disorders and conditions caused by inflammation. Cat's claw may be the next generation of the medical plant for the treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through the interference of the pro-inflammatory expression.
Mitraphylline (MTP), the major pentacyclic oxindole alkaloid presented in Uncaria tomentosa, elicited an anti-inflammatory response that modulates neutrophil activation contributing to the attenuation of inflammatory episodes.
Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.
Indenture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.
In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to lesser production of PGE2, a principal mediator of inflammation in disease production.
The effects of cat's claw in inhibited inflammatory diseases may result from its binding to proinflammatory cytokines and pathways. The use of the medical plant should be only prescribed by herbal for safety purposes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes by Akhtar N1, Miller MJ, Haqqi TM.(PubMed)
(2) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils by Montserrat-de la Paz S1, Fernandez-Arche A2, de la Puerta R2, Quilez AM2, Muriana FJ3, Garcia-Gimenez MD2, Bermudez B4.(PubMed)
(3) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark by Rojas-Duran R1, González-Aspajo G, Ruiz-Martel C, Bourdy G, Doroteo-Ortega VH, Alban-Castillo J, Robert G, Auberger P, Deharo E.(PubMed)
(4) Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report by Tay LY1, Dos Santos FA, Jorge JH.(PubMed)
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
Inflammatory diseases are disorders and conditions caused by inflammation. Cat's claw may be the next generation of the medical plant for the treatment of inflammation against various diseases. According to the study by the Case Western Reserve University, Uncaria tomentosa exhibited high levels of anti-inflammatory effects through the interference of the pro-inflammatory expression.
Mitraphylline (MTP), the major pentacyclic oxindole alkaloid presented in Uncaria tomentosa, elicited an anti-inflammatory response that modulates neutrophil activation contributing to the attenuation of inflammatory episodes.
Furthermore, the ingredient, Mitraphylline (MTP) also showed a direct effect in the immune system by reduced almost 40% of the production of interleukin 4 (IL-4) and inhibited around 50% of the release of interleukins.
Indenture Stomatitis, a chronic oral disease that affects denture wearers is caused by Candida Albicans in inducing inflammation. Topical application of a gel of 2% U. tomentosa three times a day for 1 week, cat' claw significantly reduced signs of the disease, after 1 week of treatment.
In fact, the anti-inflammatory properties may also result from their ability to inhibit TNF-alpha, a central regulator of inflammation, and to lesser production of PGE2, a principal mediator of inflammation in disease production.
The effects of cat's claw in inhibited inflammatory diseases may result from its binding to proinflammatory cytokines and pathways. The use of the medical plant should be only prescribed by herbal for safety purposes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes by Akhtar N1, Miller MJ, Haqqi TM.(PubMed)
(2) Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils by Montserrat-de la Paz S1, Fernandez-Arche A2, de la Puerta R2, Quilez AM2, Muriana FJ3, Garcia-Gimenez MD2, Bermudez B4.(PubMed)
(3) Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark by Rojas-Duran R1, González-Aspajo G, Ruiz-Martel C, Bourdy G, Doroteo-Ortega VH, Alban-Castillo J, Robert G, Auberger P, Deharo E.(PubMed)
(4) Uncaria tomentosa Gel against Denture Stomatitis: Clinical Report by Tay LY1, Dos Santos FA, Jorge JH.(PubMed)
Saturday, February 1, 2020
Herbal Chamomile in the Prevention and Treatment of Anxiety Disorders
Herbal Chamomile may have a potential effect in reducing the risk and treatment of anxiety disorder, according to studies.
Anxiety disorders are a group of mental illnesses characterized by symptoms of excessive anxiety, fear, worry, avoidance, and compulsive rituals. The condition is more commonly in women than in men.
Some researchers suggested that anxiety disorders are conditions associated with the combination of biological, psychological, and individual factors and the most commonly reported psychiatric conditions and frequently occur as comorbid disorders.
According to the statistic, anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the age of 18 and older, or 18.1% of the population every year.
The exact causes of anxiety disorders are debatable. However, a family history of anxiety recent or prolonged exposure to stress, excessive consumption of stimulants such as caffeine or tobacco is associated with the onset of the disorders.
The symptoms of anxiety disorders can be psychological or physical, including difficulty concentrating and sleeping, irritability, persistent stomachaches or diarrhea, sweaty palms, shaking and rapid heartbeat.
If you experience some of the above symptoms, please make sure you check with your doctor to rule out the possibility.
Dr. Lykouras L, the lead scientist in the investigation of the connection between body weight and anxiety disorders wrote, "Obesity has been associated with anxiety disorders as follows: most of the studies show a positive relationship with panic disorder, mainly in women, with specific phobia and social phobia" and "Some authors have found a relationship with generalized anxiety disorder but a negative relationship has been also reported".
The results clearly indicated if you are obese, your risk of anxiety disorders is increased substantially compared to normal-weight people.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae. The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and for the treatment of menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
In a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Matricaria recutita (chamomile) extract on generalized anxiety disorder (GAD) showed to effective of modest anxiolytic activity with patient mild to moderate GAD(1). The University of Ottawa study on the effects of Matricaria recutita (German chamomile) and Humulus lupulus (hops) showed significant activity in the inhibition of GAD at doses of 0.11-0.65 mg/mL(2).
The study containing 57 participants in the 2009 trial, 19 had anxiety with comorbid depression; 16 had anxiety with a past history of depression, and 22 had anxiety with no current or past depression, chamomile showed a clinically meaningful antidepressant activity to its previously observed anxiolytic activity(3).
Apigenin, a component of Matricaria recutita flowers, in mice study, exerted its anxiolytic and slight sedative effects through the central benzodiazepine receptors(4).
Researchers at the University Science Center on finding a treatment of anxiety disorder examined the effects of chamomile extract therapy in patients with mild to moderate generalized anxiety disorder (GAD) on a randomized, double-blind, placebo-controlled efficacy and tolerability trial.
In a total of 63 outpatients with mild to moderate GAD enrolled, 57 were randomized to either double-blind chamomile extract (n = 28) or placebo therapy (n = 29) for 8 weeks.
The chamomile treated group exerted a significantly greater reduction in mean total HAM-A score compared to the placebo.
Furthermore, besides the better primary outcomes, the chamomile group also demonstrated a positive change in all secondary outcomes in the reduction of anxiety symptoms.
Mild and tolerated adverse events or more were not significantly different between groups.
The findings clearly suggested herbal chamomile extract processes a modest anxiolytic activity in patients with mild to moderate GAD.
Moreover, in the evaluation of the chamomile effect on gamma-aminobutyric acid (GABA) which is a neurotransmitter that blocks impulses between nerve cells in the brain researchers compared the herbal plants which were used in the traditional medicine for the treatment of anxiety disorders.
Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter has been found to initiate the risk of anxiety or mood disorders in low levels
In vitro rat brain homogenate assays, compared to other herbal plants such as Melissa officinalis, Centella Asiatica (Gotu Kola) and Valeriana officinalis (Valerian), chamomile showed significant inhibition of glutamic acid decarboxylase (GAD) activity (0.11-0.65 mg/mL).
These results strongly suggested that the failure of the interaction of members in the GAGA system caused by dysfunction was attributed to the onset of anxiety disorders.
Additionally, in participants with symptoms of comorbid anxiety and depression, according to the generalized estimating equations analysis to identify clinically meaningful changes over time in scores from the Hamilton Depression Rating (HAM-D) questionnaire among treatment groups, Chamomile group displays a significantly greater reduction over time in total HAM-D scores compared to placebo.
Also, the HAM-D core mood item scores, application of chamomile also showed a significantly greater reduction over time vs placebo in all participants, regardless of the current or past depression.
Taken altogether, herbal chamomile may be considered a functional remedy for the prevention of anxiety disorders in the higher-risk populations and combined with primary medicine for the treatment of anxiety diseases with tolerated adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder by Amsterdam JD1, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J.(PubMed)
(2) Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system by Awad R1, Levac D, Cybulska P, Merali Z, Trudeau VL, Arnason JT. (PubMed)
(3) Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study by Amsterdam JD1, Shults J, Soeller I, Mao JJ, Rockwell K, Newberg AB. (PubMed)
(4) Anxiety disorders and obesity by Lykouras L1, Michopoulos J. (PubMed)
Anxiety disorders are a group of mental illnesses characterized by symptoms of excessive anxiety, fear, worry, avoidance, and compulsive rituals. The condition is more commonly in women than in men.
Some researchers suggested that anxiety disorders are conditions associated with the combination of biological, psychological, and individual factors and the most commonly reported psychiatric conditions and frequently occur as comorbid disorders.
According to the statistic, anxiety disorders are the most common mental illness in the U.S., affecting 40 million adults in the age of 18 and older, or 18.1% of the population every year.
The exact causes of anxiety disorders are debatable. However, a family history of anxiety recent or prolonged exposure to stress, excessive consumption of stimulants such as caffeine or tobacco is associated with the onset of the disorders.
The symptoms of anxiety disorders can be psychological or physical, including difficulty concentrating and sleeping, irritability, persistent stomachaches or diarrhea, sweaty palms, shaking and rapid heartbeat.
If you experience some of the above symptoms, please make sure you check with your doctor to rule out the possibility.
Dr. Lykouras L, the lead scientist in the investigation of the connection between body weight and anxiety disorders wrote, "Obesity has been associated with anxiety disorders as follows: most of the studies show a positive relationship with panic disorder, mainly in women, with specific phobia and social phobia" and "Some authors have found a relationship with generalized anxiety disorder but a negative relationship has been also reported".
The results clearly indicated if you are obese, your risk of anxiety disorders is increased substantially compared to normal-weight people.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae. The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and for the treatment of menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
In a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Matricaria recutita (chamomile) extract on generalized anxiety disorder (GAD) showed to effective of modest anxiolytic activity with patient mild to moderate GAD(1). The University of Ottawa study on the effects of Matricaria recutita (German chamomile) and Humulus lupulus (hops) showed significant activity in the inhibition of GAD at doses of 0.11-0.65 mg/mL(2).
The study containing 57 participants in the 2009 trial, 19 had anxiety with comorbid depression; 16 had anxiety with a past history of depression, and 22 had anxiety with no current or past depression, chamomile showed a clinically meaningful antidepressant activity to its previously observed anxiolytic activity(3).
Apigenin, a component of Matricaria recutita flowers, in mice study, exerted its anxiolytic and slight sedative effects through the central benzodiazepine receptors(4).
Researchers at the University Science Center on finding a treatment of anxiety disorder examined the effects of chamomile extract therapy in patients with mild to moderate generalized anxiety disorder (GAD) on a randomized, double-blind, placebo-controlled efficacy and tolerability trial.
In a total of 63 outpatients with mild to moderate GAD enrolled, 57 were randomized to either double-blind chamomile extract (n = 28) or placebo therapy (n = 29) for 8 weeks.
The chamomile treated group exerted a significantly greater reduction in mean total HAM-A score compared to the placebo.
Furthermore, besides the better primary outcomes, the chamomile group also demonstrated a positive change in all secondary outcomes in the reduction of anxiety symptoms.
Mild and tolerated adverse events or more were not significantly different between groups.
The findings clearly suggested herbal chamomile extract processes a modest anxiolytic activity in patients with mild to moderate GAD.
Moreover, in the evaluation of the chamomile effect on gamma-aminobutyric acid (GABA) which is a neurotransmitter that blocks impulses between nerve cells in the brain researchers compared the herbal plants which were used in the traditional medicine for the treatment of anxiety disorders.
Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter has been found to initiate the risk of anxiety or mood disorders in low levels
In vitro rat brain homogenate assays, compared to other herbal plants such as Melissa officinalis, Centella Asiatica (Gotu Kola) and Valeriana officinalis (Valerian), chamomile showed significant inhibition of glutamic acid decarboxylase (GAD) activity (0.11-0.65 mg/mL).
These results strongly suggested that the failure of the interaction of members in the GAGA system caused by dysfunction was attributed to the onset of anxiety disorders.
Additionally, in participants with symptoms of comorbid anxiety and depression, according to the generalized estimating equations analysis to identify clinically meaningful changes over time in scores from the Hamilton Depression Rating (HAM-D) questionnaire among treatment groups, Chamomile group displays a significantly greater reduction over time in total HAM-D scores compared to placebo.
Also, the HAM-D core mood item scores, application of chamomile also showed a significantly greater reduction over time vs placebo in all participants, regardless of the current or past depression.
Taken altogether, herbal chamomile may be considered a functional remedy for the prevention of anxiety disorders in the higher-risk populations and combined with primary medicine for the treatment of anxiety diseases with tolerated adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder by Amsterdam JD1, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J.(PubMed)
(2) Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system by Awad R1, Levac D, Cybulska P, Merali Z, Trudeau VL, Arnason JT. (PubMed)
(3) Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study by Amsterdam JD1, Shults J, Soeller I, Mao JJ, Rockwell K, Newberg AB. (PubMed)
(4) Anxiety disorders and obesity by Lykouras L1, Michopoulos J. (PubMed)
Chaste Tree Berry Reduced Symptoms of Pain in Severe Primary Dysmenorrhea
Chaste tree berry may have a potential effect in ameliorated the symptoms of severe uterine pain in women with primary dysmenorrhea.
Dysmenorrhea (painful menstruation) is a condition of severe uterine pain during menstruation. Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen as resulting of overproduction of certain hormones in the prostaglandins family
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the Nenehatun Hospital, In animal models, Chaste tree berry treatment significantly reduced symptoms of severe primary dysmenorrhea in the end of the third month of therapy.
In a total of 60 women with severe primary dysmenorrhea and 30 healthy women (control) included in this study. 30 patients treated with Ethinyl estradiol 0.03 mg/drospirenone (group 1) and another 30 treated with Fructus agni casti (group 2) during three menstrual cycles using the visual analog scale (VAS) scores, pulsatility index (PI), herbal plant treated group showed a higher mean PI and RI values in patients with severe primary dysmenorrhea in compared control groups on the first day of the first menstrual cycle (P < 0.0001) but the means of both values were significantly lower after the treatment in both groups compared to before values (P < 0.001 for both),
Additionally, researchers also found an increased uterine blood flow but no significant differences in terms of Doppler findings between groups 1 and 2, as women with severe symptoms of primary dysmenorrhea exhibited normally a high impedance to blood flow in uterine arteries with a preserved cyclic pattern throughout the whole cycle.
Dr. Aksoy AN, the lead author in the study said, "The effectiveness of Fructus agni casti was similar to that of ethinyl estradiol/drospirenone in patients with primary dysmenorrhea"
Other researchers also insisted that the efficacy of Chaste tree berry in reduced pain may be associated with the antinociceptive and analgesic activities, according to the petroleum ether fraction (PEF) from the aqueous ethanol extract of Vitex negundo Linn. (Verbenaceae) seeds injection into mice study conducted by the Second Military Medical University.
More importantly, another member of the Vitex group such as Vitex doniana extract may also have an effect in reduced uterine pain through regulating the hormone production of prostaglandins, ergometrine, and oxytocin which are found to have direct involvement of uterine muscle contractions.
Taking together, Chaste tree berry may be a potential herbal medicine for the treatment of painful symptoms in women with severe primary dysmenorrhea involved many mechanisms, including the antinociceptive, analgesic, hormone-regulated properties.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Evaluation of the efficacy of Fructus agni casti in women with severe primary dysmenorrhea: a prospective comparative Doppler study by Aksoy AN1, Gözükara I, Kabil Kucur S.(PubMed)
(2) Antinociceptive activities of the liposoluble fraction from Vitex negundo seeds by Zheng CJ1, Huang BK, Han T, Zhang QY, Zhang H, Rahman K, Qin LP.(PubMed)
(3) Activity of aqueous extract of the bark of Vitex doniana on uterine muscle response to drugs by Ladeji O1, Udoh FV, Okoye ZS.(PubMed)
Dysmenorrhea (painful menstruation) is a condition of severe uterine pain during menstruation. Some women may experience periodic pains during or prior to, or after menstrual periods in the lower abdomen as resulting of overproduction of certain hormones in the prostaglandins family
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the Nenehatun Hospital, In animal models, Chaste tree berry treatment significantly reduced symptoms of severe primary dysmenorrhea in the end of the third month of therapy.
In a total of 60 women with severe primary dysmenorrhea and 30 healthy women (control) included in this study. 30 patients treated with Ethinyl estradiol 0.03 mg/drospirenone (group 1) and another 30 treated with Fructus agni casti (group 2) during three menstrual cycles using the visual analog scale (VAS) scores, pulsatility index (PI), herbal plant treated group showed a higher mean PI and RI values in patients with severe primary dysmenorrhea in compared control groups on the first day of the first menstrual cycle (P < 0.0001) but the means of both values were significantly lower after the treatment in both groups compared to before values (P < 0.001 for both),
Additionally, researchers also found an increased uterine blood flow but no significant differences in terms of Doppler findings between groups 1 and 2, as women with severe symptoms of primary dysmenorrhea exhibited normally a high impedance to blood flow in uterine arteries with a preserved cyclic pattern throughout the whole cycle.
Dr. Aksoy AN, the lead author in the study said, "The effectiveness of Fructus agni casti was similar to that of ethinyl estradiol/drospirenone in patients with primary dysmenorrhea"
Other researchers also insisted that the efficacy of Chaste tree berry in reduced pain may be associated with the antinociceptive and analgesic activities, according to the petroleum ether fraction (PEF) from the aqueous ethanol extract of Vitex negundo Linn. (Verbenaceae) seeds injection into mice study conducted by the Second Military Medical University.
More importantly, another member of the Vitex group such as Vitex doniana extract may also have an effect in reduced uterine pain through regulating the hormone production of prostaglandins, ergometrine, and oxytocin which are found to have direct involvement of uterine muscle contractions.
Taking together, Chaste tree berry may be a potential herbal medicine for the treatment of painful symptoms in women with severe primary dysmenorrhea involved many mechanisms, including the antinociceptive, analgesic, hormone-regulated properties.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Evaluation of the efficacy of Fructus agni casti in women with severe primary dysmenorrhea: a prospective comparative Doppler study by Aksoy AN1, Gözükara I, Kabil Kucur S.(PubMed)
(2) Antinociceptive activities of the liposoluble fraction from Vitex negundo seeds by Zheng CJ1, Huang BK, Han T, Zhang QY, Zhang H, Rahman K, Qin LP.(PubMed)
(3) Activity of aqueous extract of the bark of Vitex doniana on uterine muscle response to drugs by Ladeji O1, Udoh FV, Okoye ZS.(PubMed)
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