Inflammation is a natural response induced by the immune system in which the white blood cells in the first line of defense try to destroy the harmful pathogens before they can enter the body to multiply in the acute phase of infection
However, overproduction of pro-inflammatory cytokines in this phase can cause damage to the nearby healthy cells, leading abnormal production of collagen ratio in the initiation of scars forming.
Most pathogens are stopped in the acute phase of infection, depending on the location and the size of the wound and tissues damage.
If the immune system can not kill off all invaded pathogens with a set of period of time, it will compromise, leading to the low-grade chronic inflammation with the persistent production of pro-inflammatory cytokines in the affected area.
Long-term low-grade inflammation ultimately leads to tissues and organs damage, inducing a number of chronic illness, including diabetes and cardiovascular disease.
Symptoms of low-grade chronic inflammation include body pain as in arthritis, constant fatigue and insomnia as in cancer, depression, anxiety and mood disorders due to pain. gastrointestinal complications like constipation, diarrhea, and acid reflux, unintended weight loss or gain depending on the infected tissues and organs.
According to statistics, chronic inflammatory diseases affects approximately 350 million people worldwide and nearly 43 million people in the United States or almost 20% of the population. The prevalence of diseases associated with chronic inflammation is anticipated to increase persistently for the next 30 years, causing a financial burden on the economy and health care sector.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native in demagogical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find a natural compound for the treatment of diseases associated with chronic inflammation, including cancers, researchers examined the effects of the turmeric through its bioactive components.
According to the review of previous studies, turmeric oil, present in turmeric, can enhance the bioavailability of curcumin.
In other words, essential oil isolated from turmeric in the form of curcumin-free turmeric (CFT) components is more effective for the treatment of chronic inflammatory disease compared to other extracts.
In the components analysis, turmerin, turmerone, elemene, furanodiene, curdione, bisacurone, cyclocurcumin, calebin A, and germacrene were all contributed to the efficacy of the curcumin-free turmeric (CFT).
In examining the effect of ar-turmerone (ATM) and turmerones (TUR, a mixture of 5 sesquiterpenes including ATM) against disease associated with inflammation, researchers found that both CUR and ATM inhibited lipopolysaccharide (LPS)-induced expression of inducible forms of inflammation by exhibiting the production of free radicals and protein involved overexpression proinflammatory cytokines.
Furthermore, ATM prevented LPS-induced translocation of certain inflammatory genes.
In a colitis model, oral administration of TUR significantly protected the large bowel against 2% dextran sulfate sodium (DSS)-induced shortening of the large bowel by 52-58% and colon carcinogenesis.
Moreover, at a low dose, TUR markedly suppressed adenoma multiplicity by 73%, compared to the range of 63-69% of CUR.
Also, the combination of CUR and TUR at both low and high doses showed a complete abolish of tumor formation.
Based on the findings, Murakami A, the lead scientist in the chronic inflammatory disease team wrote, "we consider that its use in combination with CUR may become a powerful method for prevention of inflammation-associated colon carcinogenesis".
Taken altogether, turmeric in the form of essential oil, CUR, and TUR may be considered herbal remedies for the prevention and treatment of diseases associated with chronic inflammation, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric by Aggarwal BB1, Yuan W, Li S, Gupta SC. (PubMed)
(2) Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis by Murakami A1, Furukawa I, Miyamoto S, Tanaka T, Ohigashi H. (PubMed)
Friday, April 3, 2020
Thursday, April 2, 2020
Ginger, The Best Remedy for the Prevention and Treatment of Dysmenorrhea
Ginger may be the next generation of natural whole food for the prevention and treatment of menstrual pain, some scientists found.
Dysmenorrhea is a menstrual pain is pain occurred around a few days before menstruation begins.
The symptom normally lasts less than three days.
There are 2 types of dysmenorrhea
* Primary dysmenorrhea is the painful period with no other condition occurred most in the adolescence, affecting over 90% of women in the prime time of their reproductive years. In adolescence, some researchers suggested the symptoms are associated with the immature reproductive organs.
* Secondary dysmenorrhea is the painful period associated with the disorder in the woman's reproductive organs, such as endometriosis, adenomyosis, uterine fibroids, or infection.
Some women affected by the painful period may experience symptoms of It occurs in your lower abdominal pain can be felt in the hips, lower back, or thighs.
Other common symptoms may include nausea, vomiting, diarrhea, lightheadedness, headache, or fatigue.
There is no cure for dysmenorrhea. Nonsteroidal anti-inflammatory drugs (NSAIDs), the most common treatment for both primary and secondary dysmenorrhea may be effective, however, the drugs can induce some serious side effects, including liver or kidney problems. and hypertension.
If you are currently using conventional medicine for the treatment of dysmenorrhea, please sure you know all the side effects for the preventive measure.
.
In the use of diet therapy for the prevention and treatment of dysmenorrhea, Dr. Dina Abadi Bavil, the lead scientist said, "Given the scores obtained on the lifestyle questionnaire, significant differences were observed between the groups with and without dysmenorrhea in terms of eating behavior (p=0.008), physical activity (p=0.011), stress (p=0.041), and social relationships".
These results clearly suggested that a healthy diet and lifestyle play important roles in the prevention
and treatment of dysmenorrhea
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
On findings of a natural ingredient or whole food for the prevention and treatment of dysmenorrhea in the replacement of conventional medicine without inducing side effects, researchers examine the effects of ginger on primary dysmenorrhea, through searching the database of medical literature online.
Six selected studies were reviewed by 2 authors independently.
Ginger appeared more effective for reducing pain severity than placebo.
Ginger was found as effective as those of mefenamic acid (an NSAID).
The finding point to one conclusion, oral ginger could be an effective treatment for menstrual pain in dysmenorrhea.
Dr. Daily JW, the lead scientists in another search to find the evidence of ginger for treating primary dysmenorrhea launched an investigation by looking into the database of 12 medical libraries.
Seven met specific selection criteria were included in the review.
Four of the RCTs compared the therapeutic efficacy of ginger with placebo during the first 3-4 days of the menstrual cycle and were included in the meta-analysis.
The results of the in-depth differentiation showed that ginger processes a significant effect in reducing the Pain Visual Analogue Scale (PVAS) in subjects having primary dysmenorrhea.
Six RCTs out of 7 exhibited low to moderate of the risk of bias.
These results of the RCTs strongly indicated the suggestive evidence for the effectiveness of 750-2000 mg ginger powder during the first 3-4 days of the menstrual cycle for primary dysmenorrhea.
Taken altogether, ginger may be considered a functional remedy for the prevention and treatment of painful periods with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(2) Efficacy of Oral Ginger (Zingiber officinale) for Dysmenorrhea: A Systematic Review and Meta-Analysis by Chen CX1, Barrett B2, Kwekkeboom KL3. (PubMed)
(3) Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials by Daily JW1, Zhang X2, Kim DS2, Park S2. (PubMed)
(4) Comparison of lifestyles of young women with and without primary dysmenorrhea by Dina Abadi Bavil,1 Mahrokh Dolatian,2 Zohreh Mahmoodi,3,4 and Alireza Akbarzadeh Baghban. (PMC)
Dysmenorrhea is a menstrual pain is pain occurred around a few days before menstruation begins.
The symptom normally lasts less than three days.
There are 2 types of dysmenorrhea
* Primary dysmenorrhea is the painful period with no other condition occurred most in the adolescence, affecting over 90% of women in the prime time of their reproductive years. In adolescence, some researchers suggested the symptoms are associated with the immature reproductive organs.
* Secondary dysmenorrhea is the painful period associated with the disorder in the woman's reproductive organs, such as endometriosis, adenomyosis, uterine fibroids, or infection.
Some women affected by the painful period may experience symptoms of It occurs in your lower abdominal pain can be felt in the hips, lower back, or thighs.
Other common symptoms may include nausea, vomiting, diarrhea, lightheadedness, headache, or fatigue.
There is no cure for dysmenorrhea. Nonsteroidal anti-inflammatory drugs (NSAIDs), the most common treatment for both primary and secondary dysmenorrhea may be effective, however, the drugs can induce some serious side effects, including liver or kidney problems. and hypertension.
If you are currently using conventional medicine for the treatment of dysmenorrhea, please sure you know all the side effects for the preventive measure.
.
In the use of diet therapy for the prevention and treatment of dysmenorrhea, Dr. Dina Abadi Bavil, the lead scientist said, "Given the scores obtained on the lifestyle questionnaire, significant differences were observed between the groups with and without dysmenorrhea in terms of eating behavior (p=0.008), physical activity (p=0.011), stress (p=0.041), and social relationships".
These results clearly suggested that a healthy diet and lifestyle play important roles in the prevention
and treatment of dysmenorrhea
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
On findings of a natural ingredient or whole food for the prevention and treatment of dysmenorrhea in the replacement of conventional medicine without inducing side effects, researchers examine the effects of ginger on primary dysmenorrhea, through searching the database of medical literature online.
Six selected studies were reviewed by 2 authors independently.
Ginger appeared more effective for reducing pain severity than placebo.
Ginger was found as effective as those of mefenamic acid (an NSAID).
The finding point to one conclusion, oral ginger could be an effective treatment for menstrual pain in dysmenorrhea.
Dr. Daily JW, the lead scientists in another search to find the evidence of ginger for treating primary dysmenorrhea launched an investigation by looking into the database of 12 medical libraries.
Seven met specific selection criteria were included in the review.
Four of the RCTs compared the therapeutic efficacy of ginger with placebo during the first 3-4 days of the menstrual cycle and were included in the meta-analysis.
The results of the in-depth differentiation showed that ginger processes a significant effect in reducing the Pain Visual Analogue Scale (PVAS) in subjects having primary dysmenorrhea.
Six RCTs out of 7 exhibited low to moderate of the risk of bias.
These results of the RCTs strongly indicated the suggestive evidence for the effectiveness of 750-2000 mg ginger powder during the first 3-4 days of the menstrual cycle for primary dysmenorrhea.
Taken altogether, ginger may be considered a functional remedy for the prevention and treatment of painful periods with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(2) Efficacy of Oral Ginger (Zingiber officinale) for Dysmenorrhea: A Systematic Review and Meta-Analysis by Chen CX1, Barrett B2, Kwekkeboom KL3. (PubMed)
(3) Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials by Daily JW1, Zhang X2, Kim DS2, Park S2. (PubMed)
(4) Comparison of lifestyles of young women with and without primary dysmenorrhea by Dina Abadi Bavil,1 Mahrokh Dolatian,2 Zohreh Mahmoodi,3,4 and Alireza Akbarzadeh Baghban. (PMC)
Wednesday, April 1, 2020
Green Tea GTE and EGCG, The Natural Anti Chronic Fatigue Syndrome Supplements
Scientists may have found a beverage's extract and bioactive compound for the treatment of chronic fatigue syndrome (CFS), some studies suggested.
Chronic fatigue syndrome (CFS) is a medical disorder that cannot be explained by an underlying medical condition, characterized by persistently extreme fatigue that never goes away regardless of treatment.for at least 6 months.
The exact causes of chronic fatigue syndrome are unknown. However, some researchers suggested that the conditions are the results of viral infection and chronic stress syndrome.
The University of South Florida (USF Health) in the article "Chronic fatigue syndrome: The inherited virus can cause cognitive dysfunction and fatigue" wrote, "Medveczky's team discovered that untreated CIHHV-6 patients with CFS showed signs that the HHV-6 virus was actively replicating: determined by the presence of HHV-6 messenger RNA (mRNA), a substance produced only when the virus is active".
In the psychological aspects of chronic fatigue syndrome, Dr. Takakazu Oka at the International University of Health and Welfare wrote, " psychological stress is involved in the CFS onset, exacerbation, and/or relapse, while early life stress acts as a risk factor toward the development of CFS in later life" and "CFS patients may have disrupted stress systems, including HPA axis hypofunction and ANS alterations characterized by sympathetic overactivity and low vagal tone. Individuals with CFS respond to psychological stress".
Some researchers also found that elimination diets, dietary restriction and the addition of nutritional supplements to the habitual diet may have a beneficial effect in reducing fatigue.
The randomized control trials, including pilot studies, compared a form of nutritional supplement with a placebo control suggested, treatment of a combination of nicotinamide adenine dinucleotide hydride (NADH) and coenzyme Q10 (CoQ10) exerts a significant reduction of fatigue after 8 weeks, compared to placebo.
Green tea is a precious drink that processes number of health benefits known to almost everyone in Asia and the Western world.
In the concerns of the oxidative stress in the exhibited CFS, researchers at the Panjab University launched an investigation to examine the protective effect of green tea extract (GTE) and catechin in the mouse model of CFS.
CFS animals used in the study forced swimming test session of 6 minutes every day for 7 days demonstrated a significant increase in immobility time on successive days.
Treatment with GTE (25 or 50 mg/kg, i.p.) and catechin (50 or 100 mg/kg, i.p.) for 7 days reversed the dysfunction of immobility.
Furthermore, the protection of green tea extract was correlated with the lowered levels of lipid peroxidation and restoration of reduced glutathione levels in the brains of fatigued mice.
These results suggested that oxidative stress plays a pivotal role in the pathophysiology of CFS.
Dr. Singal A, the lead scientist said, "GTE and catechin could be used as potential agents in the management of CFS and warrant the inclusion of GTE and catechin in the treatment regimen of CFS patients".
Moreover, in the evaluate the pathogenesis of chronic fatigue syndrome involved increased oxide-nitrosative stress along with the generation of pro-inflammatory cytokines such as TNF-α, in chronic fatigue rats induced by a plunge of a load of 10 ± 2% body weight and forced swim inside a rectangular jar daily for 28 days, researchers found that
* Before the application of EGCG, chronic fatigue rats exhibited significant behavioral alterations along with enhanced oxido-nitrosative stress and serum TNF-α level, compared to the naive group.
* Chronic treatment with EGCG restored all the behavioral and biochemical alterations associated with chronic fatigue syndrome.
Additionally, in the study of chronic fatigue induced in mice by subjecting them to forced swim inside a rectangular jar of specific dimensions for 6 min. daily for 15 days, researchers found that Epigallocatechin gallate (EGCG; 25, 50 and 100 mg/kg, p.o.) administered daily 30 min. before a forced swim session
* Increased oxidative-nitrosative stress and tumor necrosis factor-alpha levels in the brain of mice before green tea administration compared with the naive group.
* These behavioral and biochemical alterations were restored after chronic treatment with EGCG.
Taken altogether, green tea extract (GTE) and its bioactive chemicals EGCG may have the therapeutic effect in reducing the risk and treatment of chronic fatigue syndrome
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea extract and catechin ameliorate chronic fatigue-induced oxidative stress in mice by Singal A1, Kaur S, Tirkey N, Chopra K.(PubMed)
(2) Epigallocatechin gallate ameliorates behavioral and biochemical deficits in rat model of load-induced chronic fatigue syndrome by Sachdeva AK1, Kuhad A, Chopra K.(PubMed)
(3) Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome by Sachdeva AK1, Kuhad A, Tiwari V, Arora V, Chopra K.(PubMed)
(4) Chronic fatigue syndrome: Inherited virus can cause cognitive dysfunction and fatigue Date: July 26, 2013 Source: University of South Florida (USF Health)
(5) Influence of Psychological Stress on Chronic Fatigue Syndrome by Takakazu Oka
Chronic fatigue syndrome (CFS) is a medical disorder that cannot be explained by an underlying medical condition, characterized by persistently extreme fatigue that never goes away regardless of treatment.for at least 6 months.
The exact causes of chronic fatigue syndrome are unknown. However, some researchers suggested that the conditions are the results of viral infection and chronic stress syndrome.
The University of South Florida (USF Health) in the article "Chronic fatigue syndrome: The inherited virus can cause cognitive dysfunction and fatigue" wrote, "Medveczky's team discovered that untreated CIHHV-6 patients with CFS showed signs that the HHV-6 virus was actively replicating: determined by the presence of HHV-6 messenger RNA (mRNA), a substance produced only when the virus is active".
In the psychological aspects of chronic fatigue syndrome, Dr. Takakazu Oka at the International University of Health and Welfare wrote, " psychological stress is involved in the CFS onset, exacerbation, and/or relapse, while early life stress acts as a risk factor toward the development of CFS in later life" and "CFS patients may have disrupted stress systems, including HPA axis hypofunction and ANS alterations characterized by sympathetic overactivity and low vagal tone. Individuals with CFS respond to psychological stress".
Some researchers also found that elimination diets, dietary restriction and the addition of nutritional supplements to the habitual diet may have a beneficial effect in reducing fatigue.
The randomized control trials, including pilot studies, compared a form of nutritional supplement with a placebo control suggested, treatment of a combination of nicotinamide adenine dinucleotide hydride (NADH) and coenzyme Q10 (CoQ10) exerts a significant reduction of fatigue after 8 weeks, compared to placebo.
Green tea is a precious drink that processes number of health benefits known to almost everyone in Asia and the Western world.
In the concerns of the oxidative stress in the exhibited CFS, researchers at the Panjab University launched an investigation to examine the protective effect of green tea extract (GTE) and catechin in the mouse model of CFS.
CFS animals used in the study forced swimming test session of 6 minutes every day for 7 days demonstrated a significant increase in immobility time on successive days.
Treatment with GTE (25 or 50 mg/kg, i.p.) and catechin (50 or 100 mg/kg, i.p.) for 7 days reversed the dysfunction of immobility.
Furthermore, the protection of green tea extract was correlated with the lowered levels of lipid peroxidation and restoration of reduced glutathione levels in the brains of fatigued mice.
These results suggested that oxidative stress plays a pivotal role in the pathophysiology of CFS.
Dr. Singal A, the lead scientist said, "GTE and catechin could be used as potential agents in the management of CFS and warrant the inclusion of GTE and catechin in the treatment regimen of CFS patients".
Moreover, in the evaluate the pathogenesis of chronic fatigue syndrome involved increased oxide-nitrosative stress along with the generation of pro-inflammatory cytokines such as TNF-α, in chronic fatigue rats induced by a plunge of a load of 10 ± 2% body weight and forced swim inside a rectangular jar daily for 28 days, researchers found that
* Before the application of EGCG, chronic fatigue rats exhibited significant behavioral alterations along with enhanced oxido-nitrosative stress and serum TNF-α level, compared to the naive group.
* Chronic treatment with EGCG restored all the behavioral and biochemical alterations associated with chronic fatigue syndrome.
Additionally, in the study of chronic fatigue induced in mice by subjecting them to forced swim inside a rectangular jar of specific dimensions for 6 min. daily for 15 days, researchers found that Epigallocatechin gallate (EGCG; 25, 50 and 100 mg/kg, p.o.) administered daily 30 min. before a forced swim session
* Increased oxidative-nitrosative stress and tumor necrosis factor-alpha levels in the brain of mice before green tea administration compared with the naive group.
* These behavioral and biochemical alterations were restored after chronic treatment with EGCG.
Taken altogether, green tea extract (GTE) and its bioactive chemicals EGCG may have the therapeutic effect in reducing the risk and treatment of chronic fatigue syndrome
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Green tea extract and catechin ameliorate chronic fatigue-induced oxidative stress in mice by Singal A1, Kaur S, Tirkey N, Chopra K.(PubMed)
(2) Epigallocatechin gallate ameliorates behavioral and biochemical deficits in rat model of load-induced chronic fatigue syndrome by Sachdeva AK1, Kuhad A, Chopra K.(PubMed)
(3) Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome by Sachdeva AK1, Kuhad A, Tiwari V, Arora V, Chopra K.(PubMed)
(4) Chronic fatigue syndrome: Inherited virus can cause cognitive dysfunction and fatigue Date: July 26, 2013 Source: University of South Florida (USF Health)
(5) Influence of Psychological Stress on Chronic Fatigue Syndrome by Takakazu Oka
Tuesday, March 31, 2020
Chamomile, the Anti Hypertensive Natural Whole Herb Medicine?
Chamomile may be the next potential herbal medicine for reduced risk and treatment of hypertension, new studies suggested.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae, used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising the pressure in your heart. If it stays high over time it can damage the body in many ways.
According to the UFRPNPE B. P., Chamaemelum Nobile aqueous extract (CNAE) exhibited a hypotensive effect in high blood pressure rats.
Dr. Zeggwagh NA, the lead researcher said, " Single oral administration of CNAE (140 mg/kg) produced a significant reduction (p < 0.05) in systolic blood pressure (SBP) after 24 h of the administration " and "Daily oral administration of CNAE (140 mg/kg) during 3 weeks produced a significant reduction in SBP in the day 8 (p < 0.01) of treatment"
In fact, chamomile is not one of the herbal recommended for the treatment of hypertension. but I do believe, the antihypertensive property of chamomile may attribute to its antiplatelet and cholesterol-lowering activities.
Ellen Douglas, not the researcher in the study said, "Chamomile is not one of the specific recommended alternative therapies to address high blood pressure. But for people who experience blood pressure spikes due to stress, the tea may contribute indirect benefits".
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Hypotensive effect of Chamaemelum nobile aqueous extract in spontaneously hypertensive rats by Zeggwagh NA1, Moufid A, Michel JB, Eddouks M.(PubMed)
(2) Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes by Rafraf M1, Zemestani M2, Asghari-Jafarabadi M3.(PubMed)
(3) Herbal medication: potential for adverse interactions with analgesic drugs by Abebe W1.(PubMed)
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae, used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. High blood pressure means raising the pressure in your heart. If it stays high over time it can damage the body in many ways.
According to the UFRPNPE B. P., Chamaemelum Nobile aqueous extract (CNAE) exhibited a hypotensive effect in high blood pressure rats.
Dr. Zeggwagh NA, the lead researcher said, " Single oral administration of CNAE (140 mg/kg) produced a significant reduction (p < 0.05) in systolic blood pressure (SBP) after 24 h of the administration " and "Daily oral administration of CNAE (140 mg/kg) during 3 weeks produced a significant reduction in SBP in the day 8 (p < 0.01) of treatment"
In fact, chamomile is not one of the herbal recommended for the treatment of hypertension. but I do believe, the antihypertensive property of chamomile may attribute to its antiplatelet and cholesterol-lowering activities.
Ellen Douglas, not the researcher in the study said, "Chamomile is not one of the specific recommended alternative therapies to address high blood pressure. But for people who experience blood pressure spikes due to stress, the tea may contribute indirect benefits".
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(1) Hypotensive effect of Chamaemelum nobile aqueous extract in spontaneously hypertensive rats by Zeggwagh NA1, Moufid A, Michel JB, Eddouks M.(PubMed)
(2) Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes by Rafraf M1, Zemestani M2, Asghari-Jafarabadi M3.(PubMed)
(3) Herbal medication: potential for adverse interactions with analgesic drugs by Abebe W1.(PubMed)
Monday, March 30, 2020
Herbal Cayenne, the Natural Whole Food Medicine for Reduced Risk of Airway Inflammation
The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases, including inflammation.
Cayenne, has been used in traditional medicine for the treatment of inflammation caused by the invasion of microbial organisms and allergens.
Red pepper (Capsicum baccatum) extracts, according to the study by the Federal University of Rio Grande do Sul (UFRGS), exerted its anti-inflammatory properties through in inhibiting the neutrophil migration induced by carrageenan (Cg).
In an animal study, the ethanolic and butanol extracts (200mg/kg, p.o.) presented a significant anti-inflammatory activity through their antioxidant phenolic and flavonoid compounds against oxidative and inflammation-related pathological processes, including airway inflammation.
β-Defensin, members of the antimicrobial peptide found in cayenne inhibited the expression of the mRNA of anti-inflammatory cytokine during the bacterial invasion, through stimulating immunomodulatory effects.
Other research suggested that the anti-inflammatory effect induced by red pepper may be by inhibition of pro-inflammatory cytokine production at the inflammatory sites, such as the upper airway.
Regular intake of Cayenne pepper can improve the immune system against microbial infection and reduced the risk of airway inflammation but overdose is found to induce toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
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Sources
(1) Red Pepper (Capsicum baccatum) Extracts Present Anti-Inflammatory Effects In Vivo and Inhibit the Production of TNF-α and NO In Vitro by Allemand A1,2, Leonardi BF1, Zimmer AR1, Moreno S3, Romão PR2, Gosmann G1.(PubMed)
(2) Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation by Spiller F1, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR.(PubMed)
(3) Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach by Zimmer AR1, Leonardi B, Miron D, Schapoval E, Oliveira JR, Gosmann G.(PubMed)
(4) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
Cayenne, has been used in traditional medicine for the treatment of inflammation caused by the invasion of microbial organisms and allergens.
Red pepper (Capsicum baccatum) extracts, according to the study by the Federal University of Rio Grande do Sul (UFRGS), exerted its anti-inflammatory properties through in inhibiting the neutrophil migration induced by carrageenan (Cg).
In an animal study, the ethanolic and butanol extracts (200mg/kg, p.o.) presented a significant anti-inflammatory activity through their antioxidant phenolic and flavonoid compounds against oxidative and inflammation-related pathological processes, including airway inflammation.
β-Defensin, members of the antimicrobial peptide found in cayenne inhibited the expression of the mRNA of anti-inflammatory cytokine during the bacterial invasion, through stimulating immunomodulatory effects.
Other research suggested that the anti-inflammatory effect induced by red pepper may be by inhibition of pro-inflammatory cytokine production at the inflammatory sites, such as the upper airway.
Regular intake of Cayenne pepper can improve the immune system against microbial infection and reduced the risk of airway inflammation but overdose is found to induce toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Red Pepper (Capsicum baccatum) Extracts Present Anti-Inflammatory Effects In Vivo and Inhibit the Production of TNF-α and NO In Vitro by Allemand A1,2, Leonardi BF1, Zimmer AR1, Moreno S3, Romão PR2, Gosmann G1.(PubMed)
(2) Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation by Spiller F1, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR.(PubMed)
(3) Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach by Zimmer AR1, Leonardi B, Miron D, Schapoval E, Oliveira JR, Gosmann G.(PubMed)
(4) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2.(PubMed)
Sunday, March 29, 2020
Turmeric, The Kitchen Spice Which Cures Rheumatoid Arthritis in Vivo with No Side Effects
Rheumatoid Arthritis (RA) is a type of arthritis associated with inflammation that affects mostly the flexible (synovial) joints and tissues and organs in the body.
The disease affects more women than men and generally occurs after the ages of 40, causing the diminished quality of life of many older adults.
According to the CDC, Musculoskeletal disorders (MSDs) affect over 52 million adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.
Rheumatoid Arthritis can induce bone loss through elevating bone resorption without increasing bone formation.
A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.
The symptoms of RA that affect
* The feet and joints
Patient with rheumatoid arthritis (RA) often associates to valgus deformities of the feet and deformities of gait due to body function in an effort to support the collapsing longitudinal arch of the foot.
* The gait
Dr. Weiss RJ. and the research team at the Karolinska Institutet showed that the kinematic and kinetic gait changes in rheumatoid arthritis (RA) patients are the result of a significant reduction in joint motions, joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,
* The hands
The deformation of RA's hands can be described through the defects of bone ankylosis as a result of bone damage to the prolonged onset of the disease.
* The Muscle strength
The reduced muscle strength in patients with RA may contribute to the prevalence of functional limitations physically,
Other symptoms of RA include
* Rheumatoid Nodules
Rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with rheumatoid nodules.
* Conjunctival nodules
Although is rare in patients with rheumatoid arthritis, the appearance of the nodules may exhibit the
severity of the underlying disease.
Morning stiffness
Morning stiffness, as a marker of inflammatory activity in reflecting functional disability and pain is a very common symptom of patients in early rheumatoid arthritis.
If you have some of the aforementioned symptoms, you may have RA. Please make sure you check with your doctor to rule out the possibility.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
With an aim to find potential treatment of rheumatoid arthritis (RA), researchers investigated the protective activity of two different doses of a mixture of ginger and turmeric rhizomes powder suspended in distilled water (GTaq) against inflammation in an animal model.
Rats adjuvant-induced arthritis (AIA) by a single intradermal injection of 0.1 mL of Complete Freund's adjuvant (containing heat-killed Mycobacterium tuberculosis) into the palmar surface of the left hind paw were given orally and daily (for 28 consecutive days) distilled water as vehicle, indomethacin (1.0 mg/kg body weight), or GTaq (200 or 400 mg/kg body weight) from the day of arthritis induction.
Suspended in distilled water (GTaq) is more effective (4.2-38.4% higher, P < 0.05-0.001) than indomethacin (a non-steroidal/anti-inflammatory drug) in alleviating the loss in body weight gain, the histopathological changes in ankle joints.
Blood leukocytosis and thrombocytosis associated with the inflammation also reduced by suspended in distilled water (GTaq).
Rish factors involved the risk of cardiovascular disease and kidney damage rats adjuvant-induced arthritis were also decreased by the injection of GTaq.
Further differentiation of the anti-RA activity of GTaq, researchers found that the efficacy of the mixture was attributed to the increasing the food intake and decreasing the systemic inflammation associated with the inhibition of polyarthritis, oxidative stress, and dyslipidemia.
Based on the findings, researchers said, "Ginger-turmeric rhizomes mixture may be effective against RA severity and complications as shown in an AIA rat model".
In order to obtain more information about turmeric anti RA activity, researchers investigated the curcuminoid-containing turmeric extracts in the prevention or treatment of arthritis using streptococcal cell wall (SCW)-induced arthritis.
According to the tested assays, essential oil-depleted turmeric fraction containing 41% of the three major curcuminoids was efficacious in preventing joint inflammation at the start of the disease but not after, the onset of joint inflammation.
Interestingly, compared to other curcumin treatment groups, a commercial sample containing 94% of the three major curcuminoids was more potent in preventing arthritis in the same dose per weight.
These results strongly suggested only the three major curcuminoids found in turmeric process antiarthritic effect, compared to the treatment of the whole food.
In other words, all compounds except three major curcuminoids of the crude turmeric extract may inhibit this protective effect.
Taken altogether, turmeric used alone or combined with other herbal medicines may be considered supplements for the prevention and treatment of RA, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
rheumatoid arthritis
(1) Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis by Ramadan G1, El-Menshawy O. (PubMed)
(2) Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis by Funk JL1, Oyarzo JN, Frye JB, Chen G, Lantz RC, Jolad SD, Sólyom AM, Timmermann BN. (PubMed)
Saturday, March 28, 2020
Herbal Cascara Sagrada (Rhamnus purshiana) and Anti bacterial effects
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America, it's bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing, etc.,
The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
The Ingredients
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
The Benefits
Methicillin-resistant Staphylococcus aureus (MRSA) is a substantial contributor to morbidity and mortality. Emodin (EM), the major component found in Cascara Sagrada and many other plants combined with ampicillin (AM) or oxacillin (OX) have a showed a
positive effects against all strains of bacterias resulted in a fractional inhibitory concentration index (FICI) ranging from 0.37-0.5 and from 0.37-0.75, respectively. Other in the study of the effect of glycoside on the antibacterial activity of aloin, showed Aloe-emodin (inhibition diameter < 5.0 mm), changed the morphology of E. coli and damaged the outer cell structure.
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References
(1) Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus.by Lee YS, Kang OH, Choi JG, Oh YC, Keum JH, Kim SB, Jeong GS, Kim YC, Shin DW, Kwon DY.(PubMed)
(2) [Relationship between antibacterial activity of aloe and its anthaquinone compounds].
[Article in Chinese] by Tian B, Hua YJ, Ma XQ, Wang GL.(PubMed)
The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases. The immune system does a great job of keeping people healthy and preventing infections. Besides foods and nutritional supplements, herbs also play an important role in helping the immune system defend against viruses and bacteria attacks.
The Ingredients
The chemical constituents of Cascara Sagrada include Aloe-emodin, Anthrquinone glycosides (Barbaloin Cascarosides A, B, C and D ChrysaloinFrangul), Chrysophanol, Emodin, Heterodianthrones palmidin A, B, and C, dianthrones, Oxanthrone, Rhein, Tannins, etc.
The Benefits
Methicillin-resistant Staphylococcus aureus (MRSA) is a substantial contributor to morbidity and mortality. Emodin (EM), the major component found in Cascara Sagrada and many other plants combined with ampicillin (AM) or oxacillin (OX) have a showed a
positive effects against all strains of bacterias resulted in a fractional inhibitory concentration index (FICI) ranging from 0.37-0.5 and from 0.37-0.75, respectively. Other in the study of the effect of glycoside on the antibacterial activity of aloin, showed Aloe-emodin (inhibition diameter < 5.0 mm), changed the morphology of E. coli and damaged the outer cell structure.
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus.by Lee YS, Kang OH, Choi JG, Oh YC, Keum JH, Kim SB, Jeong GS, Kim YC, Shin DW, Kwon DY.(PubMed)
(2) [Relationship between antibacterial activity of aloe and its anthaquinone compounds].
[Article in Chinese] by Tian B, Hua YJ, Ma XQ, Wang GL.(PubMed)
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