Gastrointestinal cancer is a medical and chronic condition caused by the alternation of cell DNA in the gastrointestinal tract including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum, and anus.
Most cases of gastrointestinal cancer begin in the cell on the surface of the inner lining of the gastrointestinal tissue, before penetrating into the deeper layers.
The most common gastrointestinal cancer is gastric cancer, which is the fourth most commonly occurring cancer in men and the seventh most commonly occurring cancer in women.
According to worldwide statistics, over 1 million new cases were diagnosed in 2018 with the South Korean leading the map, second to Mongolia.
In other words, if you are Asain, you are at an increased risk of gastric cancer.
At the advanced stage, the cancer cell of the affected tissues can travel a distance away to infect the other tissues and organs, leading to secondary metastasis.
Epidemiologically, primary gastrointestinal cancer is more likely to spread to the stomach, esophageal cancer, breast cancer, renal cell carcinoma, and ovarian cancer.
Most common symptoms of gastrointestinal cancer include
* Throw up blood with the color of coffee grounds. if the bleeding cancer is located in the esophagus or stomach
* Black stool if the bleeding cancer is located in the stomach and small intestine.
* Stool red with visible blood if the bleeding cancer is located in the large intestines.
Persistent bleeding to lead anemia due to a large amount of blood loss.
If you have some of the aforementioned symptoms that do heal in a short period of time, you may have gastrointestinal cancer. Please check with your doctor to rule out the possibility.
If the bleeding is slow, it often doesn’t cause the person to throw up blood or have a change in their stool. Over time, though, slow bleeding can lead to a low red blood cell count, and make a person feel tired and weak.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural ingredient against gastrointestinal cancer, researchers examined the effects of bromelain and N-acetylcysteine, the two natural agents' anti-cancer effects.
In gastrointestinal cancer models to cisplatin, paclitaxel, 5-fluorouracil, and vincristine, a combination of bromelain and N-acetylcysteine with chemotherapeutic agents could give rise to an improved chemotherapeutic index.
In other words, chemo drugs used combined with bromelain and N-acetylcysteine are more effective in the inhibition of gastrointestinal cancer with lesser toxicity.
Furthermore, combined with bromelain and N-acetylcysteine also reduced the doses of chemo drugs used with the same efficacy.
Based on the findings, researchers said, "This represents a potentially efficacious strategy for the enhancement of microscopic cytoreduction".
Moreover, in the examination of the effects of bromelain (BR) and N-acetylcysteine (NAC) on MUC2 and MUC5AC which have been found to significantly contribute to the biology and pathogenesis of mucin-secreting gastrointestinal tumors, researchers found that in vitro (MKN45, KATOIII and LS174T cell lines) and in vivo (female nude mice bearing intraperitoneal MKN45 and LS174T), a combination of BR and NAC with dual effects on growth and mucin products of mucin-expressing tumor cells.
More precisely, the treatment of the combination of BR and NAC protected the gastric cells against the malignancies with the involvement of mucin pathology.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of gastrointestinal cancer, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potentiation of chemotherapeutics by bromelain and N-acetylcysteine: sequential and combination therapy of gastrointestinal cancer cells by Amini A1, Masoumi-Moghaddam S1, Ehteda A1, Liauw W2, Morris DL. (PubMed)
(2) Depletion of mucin in mucin-producing human gastrointestinal carcinoma: Results from in vitro and in vivo studies with bromelain and N-acetylcysteine by Amini A1, Masoumi-Moghaddam S1, Ehteda A1, Liauw W2, Morris DL. (PubMed)
Friday, May 1, 2020
Thursday, April 30, 2020
Majority of Women Chose Cinnamon Over Acetaminophen in Relieved Menstrual Pain and Heavy Menstrual Bleeding, According PubMed
Topical use of essential oil extracted from cinnamon may be the next generation whole herb medicine for prevention and treatment of menstrual pain and heavy menstrual bleeding.
The results of the investigation were reported by several respectable institutes and published on the data bases of numbers online medical literature, including PubMed.
According to the Eulji University, in the study of compared the effect of aromatherapy massage and acetaminophen on menstrual pain in Korean high school girls. cinnamon treatment group showed a significantly higher reduction of menstrual pain than in the acetaminophen group.
Acetaminophen or APAP is a over-counter and popular conventional medicine used to treat pain and fever with numbers of intolerant adverse effects.
In a randomized, double-blind trial, out of 114, group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h significantly reduced the severity and duration of pain during menstruation and menstrual bleeding.
In primary dysmenorrhea, cinnamon expressed significantly over the reduction of pain, menstrual bleeding, nausea, and vomiting with primary dysmenorrhea without side effects.
Dr. Marzouk TM., the lead author at the Mansoura University said, " ... aromatherapy abdominal massage once daily for seven days prior to menstruation using the essential oils (cinnamon....) is effective in alleviating menstrual pain, its duration and excessive menstrual bleeding...." and "Aromatherapy can be provided as a nonpharmacological pain relief measure and as a part of nursing care given to girls suffering from dysmenorrhea, or excessive menstrual bleeding".
Further study of the effect of cinnamon extract on symptoms of dysmenorrhea and contractility in some smooth muscles, Dr. Alotaibi M. suggested, cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy.
However, intake of cinnamon should be taken with care as toxicity was found in the case of overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study by Hur MH1, Lee MS, Seong KY, Lee MK.(PubMed)
(2) Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial by Jaafarpour M1, Hatefi M2, Khani A3, Khajavikhan J4.(PubMed)
(3) The effect of cinnamon on menstrual bleeding and systemic symptoms with primary dysmenorrhea by Jaafarpour M1, Hatefi M2, Najafi F3, Khajavikhan J4, Khani A3.(PubMed)
(4) The effect of aromatherapy abdominal massage on alleviating menstrual pain in nursing students: a prospective randomized cross-over study by Marzouk TM1, El-Nemer AM, Baraka HN.(PubMed)
(5) The effect of cinnamon extract on isolated rat uterine strips by Alotaibi M1.(PubMed)
The results of the investigation were reported by several respectable institutes and published on the data bases of numbers online medical literature, including PubMed.
According to the Eulji University, in the study of compared the effect of aromatherapy massage and acetaminophen on menstrual pain in Korean high school girls. cinnamon treatment group showed a significantly higher reduction of menstrual pain than in the acetaminophen group.
Acetaminophen or APAP is a over-counter and popular conventional medicine used to treat pain and fever with numbers of intolerant adverse effects.
In a randomized, double-blind trial, out of 114, group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h significantly reduced the severity and duration of pain during menstruation and menstrual bleeding.
In primary dysmenorrhea, cinnamon expressed significantly over the reduction of pain, menstrual bleeding, nausea, and vomiting with primary dysmenorrhea without side effects.
Dr. Marzouk TM., the lead author at the Mansoura University said, " ... aromatherapy abdominal massage once daily for seven days prior to menstruation using the essential oils (cinnamon....) is effective in alleviating menstrual pain, its duration and excessive menstrual bleeding...." and "Aromatherapy can be provided as a nonpharmacological pain relief measure and as a part of nursing care given to girls suffering from dysmenorrhea, or excessive menstrual bleeding".
Further study of the effect of cinnamon extract on symptoms of dysmenorrhea and contractility in some smooth muscles, Dr. Alotaibi M. suggested, cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy.
However, intake of cinnamon should be taken with care as toxicity was found in the case of overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study by Hur MH1, Lee MS, Seong KY, Lee MK.(PubMed)
(2) Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial by Jaafarpour M1, Hatefi M2, Khani A3, Khajavikhan J4.(PubMed)
(3) The effect of cinnamon on menstrual bleeding and systemic symptoms with primary dysmenorrhea by Jaafarpour M1, Hatefi M2, Najafi F3, Khajavikhan J4, Khani A3.(PubMed)
(4) The effect of aromatherapy abdominal massage on alleviating menstrual pain in nursing students: a prospective randomized cross-over study by Marzouk TM1, El-Nemer AM, Baraka HN.(PubMed)
(5) The effect of cinnamon extract on isolated rat uterine strips by Alotaibi M1.(PubMed)
Wednesday, April 29, 2020
Herbal Bilberry, the Natural Treatment for Varicose Veins with No Side Effects
Varicose veins are the medical condition in which the superficial veins have become enlarged and twisted.
The condition has been found to induce bleeding or superficial thrombophlebitis if left untreated.
The most common causes of varicose veins are found just under the skin in the legs, leading to the symptoms of fullness and pain in the affected location accompanied by symptoms of achy or heavy feeling in the legs. The pain is also worsened after a long time of sitting or standing for a long time and skin discoloration around the area.
Some patients with painful varicose veins also experience symptoms of burning, throbbing, muscle cramping, and swelling in the lower legs and itching.
Out of many risk factors associated with the onset of varicose veins, aging due to wear and tear on the valves in the veins that help regulate blood flow may be one of the most common risk factors.
Dr. Caggiati A in the study of age-related variations of varicose veins, wrote, "Varicose SVs were more frequent in the older group (62%) than in younger one (39%) owing to a higher prevalence of limbs with combined saphenous veins (SVs) and Stributaries of the SVs (STVs) varicosities (respectively, 59% and 37%)".
And, "varicose disease may progressively extend in an antegrade fashion, spreading from the STVs to the SVs".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a natural ingredient for the treatment of varicose veins and chronic venous insufficiency (CVI), researchers compared the efficacy of Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) against the therapeutic compressions.
The study included 1,051 patients who completed the registry. During the experiment, there are no safety or tolerability problems observed.
Mirtoselect (bilberry) showed a significant effect on skin flux but to a lesser extent compared to those of Venoruton, Pycnogenol, and the combination VE-PY.
The edema score was decreased more effectively with the combination and with Pycnogenol compared to the other treatment group including the Mirtoselect (bilberry).
According to the improvement in symptoms score, Pycnogenol and compression showed a larger decrease in oxidative stress compared to the Pycnogenol, Venoruton, Mirtoselect (bilberry), and with the VE-PY combination.
However, the efficacy of Pycnogenol and the combination are competitive with stockings that do not have the same tolerability in warmer climates compared to other groups.
The findings suggested that the tested compounds processed anti chronic venous insufficiency (CVI) and varicose veins properties.
Taken altogether, Mirtoselect (bilberry) may be considered a functioning remedy for the treatment of varicose veins with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings by Belcaro G1, Dugall M1, Luzzi R1, Corsi M1, Ledda A1, Ricci A1, Pellegrini L1, Cesarone MR1, Hosoi M1, Errichi BM1, Cornelli U1, Cotellese R1, Agus G1, Feragalli B. (PubMed)
(2) Age-related variations of varicose veins anatomy by Caggiati A1, Rosi C, Heyn R, Franceschini M, Acconcia MC. (PubMed)
The condition has been found to induce bleeding or superficial thrombophlebitis if left untreated.
The most common causes of varicose veins are found just under the skin in the legs, leading to the symptoms of fullness and pain in the affected location accompanied by symptoms of achy or heavy feeling in the legs. The pain is also worsened after a long time of sitting or standing for a long time and skin discoloration around the area.
Some patients with painful varicose veins also experience symptoms of burning, throbbing, muscle cramping, and swelling in the lower legs and itching.
Out of many risk factors associated with the onset of varicose veins, aging due to wear and tear on the valves in the veins that help regulate blood flow may be one of the most common risk factors.
Dr. Caggiati A in the study of age-related variations of varicose veins, wrote, "Varicose SVs were more frequent in the older group (62%) than in younger one (39%) owing to a higher prevalence of limbs with combined saphenous veins (SVs) and Stributaries of the SVs (STVs) varicosities (respectively, 59% and 37%)".
And, "varicose disease may progressively extend in an antegrade fashion, spreading from the STVs to the SVs".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a natural ingredient for the treatment of varicose veins and chronic venous insufficiency (CVI), researchers compared the efficacy of Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) against the therapeutic compressions.
The study included 1,051 patients who completed the registry. During the experiment, there are no safety or tolerability problems observed.
Mirtoselect (bilberry) showed a significant effect on skin flux but to a lesser extent compared to those of Venoruton, Pycnogenol, and the combination VE-PY.
The edema score was decreased more effectively with the combination and with Pycnogenol compared to the other treatment group including the Mirtoselect (bilberry).
According to the improvement in symptoms score, Pycnogenol and compression showed a larger decrease in oxidative stress compared to the Pycnogenol, Venoruton, Mirtoselect (bilberry), and with the VE-PY combination.
However, the efficacy of Pycnogenol and the combination are competitive with stockings that do not have the same tolerability in warmer climates compared to other groups.
The findings suggested that the tested compounds processed anti chronic venous insufficiency (CVI) and varicose veins properties.
Taken altogether, Mirtoselect (bilberry) may be considered a functioning remedy for the treatment of varicose veins with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings by Belcaro G1, Dugall M1, Luzzi R1, Corsi M1, Ledda A1, Ricci A1, Pellegrini L1, Cesarone MR1, Hosoi M1, Errichi BM1, Cornelli U1, Cotellese R1, Agus G1, Feragalli B. (PubMed)
(2) Age-related variations of varicose veins anatomy by Caggiati A1, Rosi C, Heyn R, Franceschini M, Acconcia MC. (PubMed)
Tuesday, April 28, 2020
Herbal Chaste Tree Berry Anti Estrogenic Activity
Chaste tree berry(Vitex agnus-castus), is found to process anti-estrogenic property in binding the estrogen receptors for a balance between the activities of estrogen receptor ERα or ERβ.
The herb is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Anti estrogenic effects are an act of binding the estrogen receptor(ERα ) and/ERβ in inhibiting the excessive levels of estrogen circulating in the body.
According to the University of Alabama in Huntsville, in the study of the potential effect of estrogen mimics or anti-estrogens in phytochemicals of popular dietary herbal supplements, researchers found that almost all herbal supplements containing phytochemical components showed a capability in binding to the human estrogen receptor and exhibit selective estrogen receptor modulation, including chaste tree berry.
Casticin, a flavonoid isolated from Vitex rotundifolia, significantly expressed anti estrogenic effect in reduced the prolactin release stimulated by E2 in induced inhibition of ERα mRNA expression in a concentration-dependent manner, through its anti estrogenic effect.
In a hyperprolactinemia (MIHP) induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats, rat treated with casticin (10, 20, and 40 mg/kg, ip, for 7 d) reduced serum prolactin levels by 33.9%, 54.3%, and 64.7% and at(1 and 10 micromol/L) inhibited E2-induced pituitary cell proliferation by 27.7% and 42.1%, respectively through reduced levels of 17β-Estradiol (E2) significantly.
More importantly, oral administration of casticin, a flavonoid isolated from Vitex rotundifolia displayed an anti-estrogenic activity in decrease excessive levels of 17β-Estradiol (E2) significantly
Taking together, Chaste tree berry processes strong estrogenic and anti-estrogenic effects in binding estrogen receptor sites to preserve the balancing of hormone expression of estrogen through ER alpha and ERBeta inhibition and exhibition.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements by Powers CN1, Setzer WN1.(PubMed)
(2) Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro by YE Q1, ZHANG QY, ZHENG CJ, WANG Y, QIN LP.(PubMed)
The herb is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Anti estrogenic effects are an act of binding the estrogen receptor(ERα ) and/ERβ in inhibiting the excessive levels of estrogen circulating in the body.
According to the University of Alabama in Huntsville, in the study of the potential effect of estrogen mimics or anti-estrogens in phytochemicals of popular dietary herbal supplements, researchers found that almost all herbal supplements containing phytochemical components showed a capability in binding to the human estrogen receptor and exhibit selective estrogen receptor modulation, including chaste tree berry.
Casticin, a flavonoid isolated from Vitex rotundifolia, significantly expressed anti estrogenic effect in reduced the prolactin release stimulated by E2 in induced inhibition of ERα mRNA expression in a concentration-dependent manner, through its anti estrogenic effect.
In a hyperprolactinemia (MIHP) induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats, rat treated with casticin (10, 20, and 40 mg/kg, ip, for 7 d) reduced serum prolactin levels by 33.9%, 54.3%, and 64.7% and at(1 and 10 micromol/L) inhibited E2-induced pituitary cell proliferation by 27.7% and 42.1%, respectively through reduced levels of 17β-Estradiol (E2) significantly.
More importantly, oral administration of casticin, a flavonoid isolated from Vitex rotundifolia displayed an anti-estrogenic activity in decrease excessive levels of 17β-Estradiol (E2) significantly
Taking together, Chaste tree berry processes strong estrogenic and anti-estrogenic effects in binding estrogen receptor sites to preserve the balancing of hormone expression of estrogen through ER alpha and ERBeta inhibition and exhibition.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements by Powers CN1, Setzer WN1.(PubMed)
(2) Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro by YE Q1, ZHANG QY, ZHENG CJ, WANG Y, QIN LP.(PubMed)
Monday, April 27, 2020
Dandelion (Taraxacum officinale) Processes a Strong Antifungal Activity
Fungal infection is a common disease caused by the overgrowth of fungus.
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
Yeasts, molds, and mushrooms are types of fungi. The tiny microorganisms have cells with nuclear.
Most common fungal infections start from the lungs or the skin. Long-term use of antibiotics and people with the weakened immune system is susceptible to fungal infection, epidemiologically.
However, some researchers suggested that common risk factors for fungal infection also include pregnancy, diabetes mellitus, oral contraceptives, and inadequate therapy.
People with weakened immune systems such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes includes jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,......, and burning sensation.
In women, signs of a yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........, and unusual vaginal discharge.
In men, signs of a yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of fungal infectious diseases,
scientists examined the antifungal effects of novel peptide named ToAMP4 isolated from Taraxacum officinale Wigg. flowers by a combination of acetic acid extraction and different types of chromatography.
According to the tested differentiation of the biological activity of ToAMP4 produced in a prokaryotic expression system as a fusion protein with thioredoxin, the peptide ToAMP4 displayed broad-spectrum antifungal activity against phytopathogens.
Moreover, the two ToAMP4 also exerted significantly mediated inhibition properties, on the tested fungus
In other words, ToAMP4 processed anti-fungal infection depending on the types of fungus.
Taken altogether, dandelion may be considered a remedy for the prevention and treatment of fungal infection, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A novel cysteine-rich antifungal peptide ToAMP4 from Taraxacum officinale Wigg. flowers by Astafieva AA1, Rogozhin EA, Andreev YA, Odintsova TI, Kozlov SA, Grishin EV, Egorov TA. (PubMed)
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
Yeasts, molds, and mushrooms are types of fungi. The tiny microorganisms have cells with nuclear.
Most common fungal infections start from the lungs or the skin. Long-term use of antibiotics and people with the weakened immune system is susceptible to fungal infection, epidemiologically.
However, some researchers suggested that common risk factors for fungal infection also include pregnancy, diabetes mellitus, oral contraceptives, and inadequate therapy.
People with weakened immune systems such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes includes jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,......, and burning sensation.
In women, signs of a yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........, and unusual vaginal discharge.
In men, signs of a yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of fungal infectious diseases,
scientists examined the antifungal effects of novel peptide named ToAMP4 isolated from Taraxacum officinale Wigg. flowers by a combination of acetic acid extraction and different types of chromatography.
According to the tested differentiation of the biological activity of ToAMP4 produced in a prokaryotic expression system as a fusion protein with thioredoxin, the peptide ToAMP4 displayed broad-spectrum antifungal activity against phytopathogens.
Moreover, the two ToAMP4 also exerted significantly mediated inhibition properties, on the tested fungus
In other words, ToAMP4 processed anti-fungal infection depending on the types of fungus.
Taken altogether, dandelion may be considered a remedy for the prevention and treatment of fungal infection, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A novel cysteine-rich antifungal peptide ToAMP4 from Taraxacum officinale Wigg. flowers by Astafieva AA1, Rogozhin EA, Andreev YA, Odintsova TI, Kozlov SA, Grishin EV, Egorov TA. (PubMed)
Sunday, April 26, 2020
Cinnamon, The Whole Herbal Medicine for Osteopenic Disease
Recent study suggested that cinnamon may be effective in prevented and treatment of osteopenic disease by inhibiting protein in transferred information of cytokine production involved cell survival.
Cinnamon is a spice derived from the inner bark of the tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The osteopenic disease is the early stage of osteoporosis involved the deletion of bone density in comparison to the healthy person.
According to the Keio University, cinnamon suppressed the osteoclastogenesis, protected bone density against erosion, interleukin-4 (IL-4), an anti-inflammatory cytokine, involved the production of white blood cell in inhibition of osteoclast differentiation through the expression of T cell of the immune system
Dr. Tsuji-Naito K. in the study of Interleukin-4 suggested that Cinnamomum zeylanicum (C. zeylanicum) exhibited strong inhibitory effects on osteoclastogenesis,......involved the regulation of white blood cells in osteoclastogenesis.
In a comprehensive systematic review of vitro and in-vivo, using databases from PubMed, Web of Science, SciVerse Scopus published before 31st December 2012, cinnamon has shown to express inhibitory effects on osteoclastogenesis with minimal toxic and adverse effects.
The effectiveness of cinnamon in reduced risk of Osteopenic diseases in inducing bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis may result in inhibition of inflammatory cytokines expression in the immune system. Use of cinnamon should be taken with care, as the herbal medicine has induced toxicity if overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1 by Takatsuna H1, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.(PubMed)
(2) Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation by Tsuji-Naito K1.(PubMed)
(3) Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review by Ranasinghe P1, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P.(PubMed)
Cinnamon is a spice derived from the inner bark of the tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The osteopenic disease is the early stage of osteoporosis involved the deletion of bone density in comparison to the healthy person.
According to the Keio University, cinnamon suppressed the osteoclastogenesis, protected bone density against erosion, interleukin-4 (IL-4), an anti-inflammatory cytokine, involved the production of white blood cell in inhibition of osteoclast differentiation through the expression of T cell of the immune system
Dr. Tsuji-Naito K. in the study of Interleukin-4 suggested that Cinnamomum zeylanicum (C. zeylanicum) exhibited strong inhibitory effects on osteoclastogenesis,......involved the regulation of white blood cells in osteoclastogenesis.
In a comprehensive systematic review of vitro and in-vivo, using databases from PubMed, Web of Science, SciVerse Scopus published before 31st December 2012, cinnamon has shown to express inhibitory effects on osteoclastogenesis with minimal toxic and adverse effects.
The effectiveness of cinnamon in reduced risk of Osteopenic diseases in inducing bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis may result in inhibition of inflammatory cytokines expression in the immune system. Use of cinnamon should be taken with care, as the herbal medicine has induced toxicity if overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1 by Takatsuna H1, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.(PubMed)
(2) Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation by Tsuji-Naito K1.(PubMed)
(3) Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review by Ranasinghe P1, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P.(PubMed)
Saturday, April 25, 2020
Herbal Butterbur, the Anti Asthma Functional Remedy
Scientists may have found a medicinal plant for the prevention and treatment of asthma with no side effects, according to studies.
Asthma is a chronic inflammatory disease, affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.
Most signs and symptoms of asthma are triggered by exposure to various irritants and substances such as allergens.
Researchers do not know why some people are prone to the substances that trigger the symptoms of asthma while others do not, even process the same health conditions in the same family.
According to the American Lung Association, there are many risk factors can trigger the onset of the diseases, including respiratory problems during infancy and childhood such as wheezing, children who experience viral respiratory infections, children who have an allergic condition, such as atopic dermatitis (eczema) or allergic rhinitis (hay fever), can also develop asthma.
The most preventable risk factors that cause the onset of adults asthma are smoking and obesity. Dr. Chen Y and colleagues at the University of Ottawa in the investigation of the risk asthma in among female Canadians wrote, "The prevalence of asthma was 10.4% for males and 11.2% for females aged 12-24 years. Among the subjects aged 25 years or more, the prevalence varied from 4.1% to 5.8% for men and from 4.9% to 6.4% for women".
And, "Female smokers demonstrated a 1.7-fold increase in the prevalence of asthma compared with female nonsmokers" and " the prevalence of asthma increased with increasing body mass index in females".
The results strongly suggested that if you are female and you don't want to have asthma, you must lose weight and quit smoking.
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.
It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.
With an aim to find a natural remedy for the treatment of asthma with no side effects, researchers at the examine the phytoceuticals (non-nutritional but beneficial plant chemicals) used as a pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD).
Recently, herbal butterbur has been found to benefit and improve treatments for lung disease, particularly in that of airway inflammatory disease, including asthma and chronic obstructive pulmonary disease (COPD.
Ovalbumin (OVA) immunized BALB/c mice selected to the experiment were given intranasally together with antigen challenge in the murine model of allergic airway disease (asthma)
The analysis of the inflammatory and immune parameters in the lung suggested FET treated mice exerted a significant effect in inhibiting the allergic response.
Furthermore, PET also inhibited airway hyperresponsiveness (AHR) and eosinophil recruitment into the bronchoalveolar lavage (BAL) fluid upon allergen challenge observed by a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs but had no effect in the saline control mice.
According to the reading eosinophilic activation marker, PET at a concentration of 100 microg strongly lowered the levels of serum eosinophil peroxidase (EPO).
These results suggested inflammation, eosinophil recruitment, and mucus hyperproduction are significantly decreased in the lung with the administration of 100 microg PET.
Moreover, at the concentration of 30 microg PET, researchers found that airway hyperresponsiveness (AHR) and inflammation of treated mice associated with the production of inflammatory cytokines reduced (IL-4, IL-5) and RANTES production involved the mediation of acute and chronic inflammation are strongly reduced without affecting the expression of IgE and eotaxin serum levels.
Where Eotaxin is a small protein produced in the lungs of asthmatic patients.
The finding indicated PET inhibited the expression of asthma through decreasing the airway hyperresponsiveness, airway inflammation, eosinophil recruitment, and mucus hyperproduction of the asthmatic mice, in a dose-dependent manner.
Taken altogether, herbal butterbur may be considered a natural remedy for the prevention and combined with conventional medicine for the treatment of asthma and COPD with no side effects, pending to the confirmation of the large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.
Grandhi S, Donnelly LE, Rogers DF.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A1, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
(3) Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994-1995 by Chen Y1, Dales R, Krewski D, Breithaupt K. (PubMed)
Asthma is a chronic inflammatory disease, affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.
Most signs and symptoms of asthma are triggered by exposure to various irritants and substances such as allergens.
Researchers do not know why some people are prone to the substances that trigger the symptoms of asthma while others do not, even process the same health conditions in the same family.
According to the American Lung Association, there are many risk factors can trigger the onset of the diseases, including respiratory problems during infancy and childhood such as wheezing, children who experience viral respiratory infections, children who have an allergic condition, such as atopic dermatitis (eczema) or allergic rhinitis (hay fever), can also develop asthma.
The most preventable risk factors that cause the onset of adults asthma are smoking and obesity. Dr. Chen Y and colleagues at the University of Ottawa in the investigation of the risk asthma in among female Canadians wrote, "The prevalence of asthma was 10.4% for males and 11.2% for females aged 12-24 years. Among the subjects aged 25 years or more, the prevalence varied from 4.1% to 5.8% for men and from 4.9% to 6.4% for women".
And, "Female smokers demonstrated a 1.7-fold increase in the prevalence of asthma compared with female nonsmokers" and " the prevalence of asthma increased with increasing body mass index in females".
The results strongly suggested that if you are female and you don't want to have asthma, you must lose weight and quit smoking.
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.
It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.
With an aim to find a natural remedy for the treatment of asthma with no side effects, researchers at the examine the phytoceuticals (non-nutritional but beneficial plant chemicals) used as a pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD).
Recently, herbal butterbur has been found to benefit and improve treatments for lung disease, particularly in that of airway inflammatory disease, including asthma and chronic obstructive pulmonary disease (COPD.
Ovalbumin (OVA) immunized BALB/c mice selected to the experiment were given intranasally together with antigen challenge in the murine model of allergic airway disease (asthma)
The analysis of the inflammatory and immune parameters in the lung suggested FET treated mice exerted a significant effect in inhibiting the allergic response.
Furthermore, PET also inhibited airway hyperresponsiveness (AHR) and eosinophil recruitment into the bronchoalveolar lavage (BAL) fluid upon allergen challenge observed by a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs but had no effect in the saline control mice.
According to the reading eosinophilic activation marker, PET at a concentration of 100 microg strongly lowered the levels of serum eosinophil peroxidase (EPO).
These results suggested inflammation, eosinophil recruitment, and mucus hyperproduction are significantly decreased in the lung with the administration of 100 microg PET.
Moreover, at the concentration of 30 microg PET, researchers found that airway hyperresponsiveness (AHR) and inflammation of treated mice associated with the production of inflammatory cytokines reduced (IL-4, IL-5) and RANTES production involved the mediation of acute and chronic inflammation are strongly reduced without affecting the expression of IgE and eotaxin serum levels.
Where Eotaxin is a small protein produced in the lungs of asthmatic patients.
The finding indicated PET inhibited the expression of asthma through decreasing the airway hyperresponsiveness, airway inflammation, eosinophil recruitment, and mucus hyperproduction of the asthmatic mice, in a dose-dependent manner.
Taken altogether, herbal butterbur may be considered a natural remedy for the prevention and combined with conventional medicine for the treatment of asthma and COPD with no side effects, pending to the confirmation of the large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.
Grandhi S, Donnelly LE, Rogers DF.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A1, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
(3) Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994-1995 by Chen Y1, Dales R, Krewski D, Breithaupt K. (PubMed)
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