Chronic allergic airways disease (AAD) is a group of the disease characterized by airway inflammation and airway hyperresponsiveness (AHR).
Airway inflammation is the hallmark of chronic obstructive pulmonary disease (COPD) associated with low-grade inflammation caused by persistent production of proinflammatory cytokines by the immune system in the airway.
On the other hand, airway hyperresponsiveness (AHR) is a cardinal feature of asthma associated with the response of the immune system against pathogens.
The most common symptoms of coughing, wheezing, and shortness of breath in reactive airway disease (AAD) may not be due to asthma or other chronic airways conditions.
Conventionally, reactive airway inflammatory disease is treated with medication to control symptoms such as long-term use of an inhaler to relieve attacks and improved quality of life through avoidance of irritants.
If the cause of reactive airway disease is found, most cases of the condition may be cured by medication.
Dr. Jill R. Johnson, the lead scientist in the examination of Allergic Airway Disease: More than Meets the IgE? wrote, "After exposure, allergens crosslink with IgE on mast cells and induce histamine and leukotriene release (6), thereby initiating the allergic response and leading to the classic symptoms of allergy, i.e., sneezing and wheezing".
And, ". Omalizumab binds to the Ce3 domain of free IgE with high affinity (7), thereby inhibiting early- and late-phase asthmatic reactions (8) and decreasing the frequency of exacerbations in severe asthmatics (9). Omalizumab binding also prevents IgE from interacting with Fc«RI and Fc«RII1 on effector cells (mast cells, B cells, eosinophils, dendritic cells, and monocytes), thus impairing their activation and making them less sensitive to allergens, and disabling signaling cascades (10), with the end result of a reduction in symptoms".
In other words, allergic airway disease (AAD) is a result of an immune response upon exposure to the allergens, Therefore, by making the immune system less sensitive to allergens, symptoms of allergic airway disease (AAD) may be reduced.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to discover a potential compound for the treatment of diseases associated with chronic inflammation, researchers examined the ability of bromelain in reducing the inflammation of preexisting asthma via ovalbumin (OVA)-induced murine model of allergic airway disease (AAD).
The study included female C57BL/6J mice with intraperitoneal OVA/alum and then challenged them with OVA aerosolization for 10 consecutive days.
On day 4, phosphate buffered saline (PBS) was administrated to the control group (n = 10) and bromelain (6mg/kg) in PBS were administrated to the bromelain (intervention) group (n = 10).
According to the tested assays, bromelain treatment of AAD mice (bromelain group) showed a significant anti-inflammatory activity indicated by reduced BAL total leukocytes, eosinophils, and cellular infiltrates via lung pathology compared to the control group.
Furthermore, bromelain also significantly reduced bronchoalveolar lavage (BAL) CD4+ associated and CD8+ T cells d with the T helper 2 (TH2) cells in the promotion of allergic inflammation process without affecting cell numbers in the spleen or hilar lymph node.
The efficacy bromelain in the inhibition was attributed to the decreased interleukins involved in the production of pro-inflammatory cytokines.
In other words, bromelain protects asthma patients against allergic airway inflammation through its strong anti-inflammatory property.
Based on the results, researchers said, "bromelain has a therapeutic effect in established AAD, which may translate into an effective adjunctive therapy in patients with similar conditions, such as allergic asthma, who have chosen to initiate treatment after the onset of symptoms".
In order to find more information about bromelain anti-ADD activity, researchers investigated the effect of bromelain treatment in an ovalbumin (OVA)-induced murine model of allergic airway disease (AAD).
Selected mice were sensitized with intraperitoneal (i.p.) OVA/alum and challenged with daily OVA aerosols to induce ADD followed by the treatment of either saline, 2 or 6 mg/kg bromelain, twice daily for four consecutive days.
According to the findings, bromelain showed a similar effect as the aforementioned results in reduced total BAL leukocytes, eosinophils, CD4+, and CD8+ T lymphocytes, CD4+/CD8+ T cell ratio, and IL-13.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of allergic airway disease ADD, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain limits airway inflammation in an ovalbumin-induced murine model of established asthma by Secor ER Jr1, Shah SJ, Guernsey LA, Schramm CM, Thrall RS. (PubMed)
(2) Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease by Secor ER Jr1, Carson WF 4th, Cloutier MM, Guernsey LA, Schramm CM, Wu CA, Thrall RS. (PubMed)
(3) Allergic Airway Disease: More than Meets the IgE? by Jill R. Johnson, Ph.D. and James A. Harker, Ph.D
Friday, August 28, 2020
Thursday, August 27, 2020
Cranberry, the Remedy for Reducing the Risk Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)
The liver is the largest internal organ found in the human which plays an essential role in filtering the blood from the digestive system before passing them to other parts of the body.
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reduction partly or completely the function of the liver, including liver failure.
Nonalcoholic fatty liver disease (NAFLD) is a chronic condition caused by fat accumulated in the liver over time, in the absence of excessive alcohol use. The disease can be classified into the types of non-inflammatory fatty liver (NAFl) and inflammatory nonalcoholic steatohepatitis (NASH)(1).
Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of cirrhosis and liver cancer.
According to world statistics, nonalcoholic fatty liver disease (NAFLD) is normally known as a disease of the Western world(2). However, due to the economic prosperity of Southeast Asian(3), the disease also was found in a large population in the cities, causing concerns of many scientists in the region(4)(6).
According to the joint assessment of the prevalence of non-alcoholic fatty liver disease and risk factors for advanced fibrosis and mortality in the US, led by the Stanford University School of Medicine, "The prevalence of NAFLD in the United States (U.S.) has risen from 18% in 1988–1991 to 31% in 2011–2012. Estimates of NAFLD prevalence for adults in Western countries are 20–30%, with much higher prevalence in adults with obesity (80–90%), diabetes (30–50%), and hyperlipidemia (90%)"(5).
The exact causes of NAFLD aren't well understood. Some researchers suggested that certain risk factors such as long-term use of certain medications(8), genetic preposition(8), insulin resistance(8), high cholesterol(8) and triglycerides(8) in the blood, polycystic ovary syndrome(8), metabolic syndrome(8), obesity(8), and type 2 diabetes(8) are associated with the onset of the disease.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the prevention and treatment of liver diseases, researchers investigated cranberry effects on metabolic profiles, including that during the progression of non-alcoholic fatty liver disease (NAFLD), in a high-fat diet (HFD)-fed C57BL/6 mice.
According to the results of the experiment, the application of cranberry reduced the levels of oxidative stress in mice that were fed HFD diets with supplementation of 1 and 5% cranberry powder, compared to HFD-fed control mice.
1 week after beginning the diets to the end of the study, the bodyweight of mice in the cranberry-treatment groups was significantly lower, compared to mice in the HFD-fed control group.
Furthermore, during the early treatment phase, the injection of cranberry suppressed the elevation of serum triglycerides, leading to the smaller of the adipocytes in the adipose tissues in HFD-fed mice compared to the cells in HFD-fed control mice.
More importantly, the nonalcoholic fatty liver disease (NAFLD) characteristics of the levels of lipid-droplet formation and hepatocyte ballooning in the liver were drastically decreased in cranberry-supplemented-HFD-fed mice relative to the levels in HFD-fed control mice.
Based on the findings, researchers said, " Cranberry ameliorates HFD-induced metabolic disturbances, particularly during the early treatment stage, and exhibits considerable potential for preventing the progression of NAFLD.".
Taken altogether, cranberry may be considered a functional food for the treatment of NAFLD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice by Shimizu K1, Ono M2, Imoto A1, Nagayama H1, Tetsumura N1, Terada T1, Tomita K2, Nishinaka T. (PubMed)
(2) Non-alcoholic Fatty Liver Disease (NAFLD)Treatment in Phytochemicals Perspective by Kyle J. Norton
The liver also produces cholesterol, a waxy substance which aids digestion, builds cell membranes and produces vitamin D and steroid hormones.
Liver disease is a class of medical conditions characterized by the reduction partly or completely the function of the liver, including liver failure.
Nonalcoholic fatty liver disease (NAFLD) is a chronic condition caused by fat accumulated in the liver over time, in the absence of excessive alcohol use. The disease can be classified into the types of non-inflammatory fatty liver (NAFl) and inflammatory nonalcoholic steatohepatitis (NASH)(1).
Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of cirrhosis and liver cancer.
According to world statistics, nonalcoholic fatty liver disease (NAFLD) is normally known as a disease of the Western world(2). However, due to the economic prosperity of Southeast Asian(3), the disease also was found in a large population in the cities, causing concerns of many scientists in the region(4)(6).
According to the joint assessment of the prevalence of non-alcoholic fatty liver disease and risk factors for advanced fibrosis and mortality in the US, led by the Stanford University School of Medicine, "The prevalence of NAFLD in the United States (U.S.) has risen from 18% in 1988–1991 to 31% in 2011–2012. Estimates of NAFLD prevalence for adults in Western countries are 20–30%, with much higher prevalence in adults with obesity (80–90%), diabetes (30–50%), and hyperlipidemia (90%)"(5).
The exact causes of NAFLD aren't well understood. Some researchers suggested that certain risk factors such as long-term use of certain medications(8), genetic preposition(8), insulin resistance(8), high cholesterol(8) and triglycerides(8) in the blood, polycystic ovary syndrome(8), metabolic syndrome(8), obesity(8), and type 2 diabetes(8) are associated with the onset of the disease.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the prevention and treatment of liver diseases, researchers investigated cranberry effects on metabolic profiles, including that during the progression of non-alcoholic fatty liver disease (NAFLD), in a high-fat diet (HFD)-fed C57BL/6 mice.
According to the results of the experiment, the application of cranberry reduced the levels of oxidative stress in mice that were fed HFD diets with supplementation of 1 and 5% cranberry powder, compared to HFD-fed control mice.
1 week after beginning the diets to the end of the study, the bodyweight of mice in the cranberry-treatment groups was significantly lower, compared to mice in the HFD-fed control group.
Furthermore, during the early treatment phase, the injection of cranberry suppressed the elevation of serum triglycerides, leading to the smaller of the adipocytes in the adipose tissues in HFD-fed mice compared to the cells in HFD-fed control mice.
More importantly, the nonalcoholic fatty liver disease (NAFLD) characteristics of the levels of lipid-droplet formation and hepatocyte ballooning in the liver were drastically decreased in cranberry-supplemented-HFD-fed mice relative to the levels in HFD-fed control mice.
Based on the findings, researchers said, " Cranberry ameliorates HFD-induced metabolic disturbances, particularly during the early treatment stage, and exhibits considerable potential for preventing the progression of NAFLD.".
Taken altogether, cranberry may be considered a functional food for the treatment of NAFLD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry Attenuates Progression of Non-alcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice by Shimizu K1, Ono M2, Imoto A1, Nagayama H1, Tetsumura N1, Terada T1, Tomita K2, Nishinaka T. (PubMed)
(2) Non-alcoholic Fatty Liver Disease (NAFLD)Treatment in Phytochemicals Perspective by Kyle J. Norton
Wednesday, August 26, 2020
Cranberry Effects on Diabetes and Hypertension Management
Diabetes is a medical condition caused by not insufficient insulin entering the bloodstream.
In other words, diabetes is a condition associated with the inability of the body to use insulin properly.
Most cases of insulin insufficiency in the bloodstream in diabetes are either caused by the gradual died-off of the pancreas beta cells or insulin receptors clogged-up by fat and cholesterol.
Hallmarks of diabetes are hyperglycemia and insulin resistance.
According to the statistics, in 2017, 7.3% of Canadians aged 12 and older (roughly 2.3 million people) reported being diagnosed with diabetes.
Most common causes of diabetes are metabolic syndrome, a cluster of conditions including high blood pressure, cholesterol, and glucose, gestational diabetes, prediabetes, damage to the pancreas causes the gradual and irreversible loss of beta cells that reduce the production of insulin, and influenza a viruses
Hypertension, a condition associated with the cluster of metabolic syndrome is a medical condition associated with abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and changes constantly depending on activity. However, persistent hypertension due to poor management over time can lead to diabetes and cardiovascular disease.
According to the statistics provided by the American Heart Association., nearly half of all adults in the United States are living with high blood pressure or 1 in 3 American are hypertensive.
Hypertension is leading risk factors of heart disease and stroke that cause most death in the US
The most common prevalent factors associated with the condition onset are family history, aging, being male, being overweight or obese, ethnicity, physical inactivity, unhealthy diet and medical condition such as chronic kidney disease.
Believe it or not, excessive alcohol drinking is also one of the major causes besides obesity in elevating the syndrome onset.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the management of blood pressure, researchers examined the effect of a water-soluble cranberry-based phytochemical combination with oregano, rosemary, and Rhodiola Rosea against hypertension.
According to the tested analysis, the 75% cranberry with 25% oregano combinations showed the highest antioxidant phenolics (38.9 mg/g DW) comapred to other combinations by inhibition of free radical DPPH inhibition by 73.6 %.
Furthermore, 75% cranberry and 25% Rhodiola Rosea combination had the highest alpha-glucosidase activity among the combinations.
Alpha-amyloid associated diabetes also was associated with 75% cranberry with 25% Rhodiola Rosea combination comapred to other combinations.
Additionally, anti-ACE-I inhibitory activity against the risk of hypertension was also inhibited by the 75% cranberry with 25% rosemary comapred to other combinations.
In other words, cranberry combined with other herbal medicine protects patients with diabetes and hypertension against complications by inhibiting the levels of alpha-glucosidase, alpha-amyloid, and ACE-I
Based on the results, researchers said, "The analysis of alpha-glucosidase,alpha-amylase, and ACE-I inhibitory activities suggested that inhibition depends on the phenolic profile of each unique extract and by bringing together synergistic combinations to cranberry, health beneficial functionality was enhanced".
Taken altogether, cranberry may be considered a remedy for the management of diabetes and hypertension, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potential of cranberry-based herbal synergies for diabetes and hypertensionmanagement by Apostolidis E1, Kwon YI, Shetty K. (PubMed)
In other words, diabetes is a condition associated with the inability of the body to use insulin properly.
Most cases of insulin insufficiency in the bloodstream in diabetes are either caused by the gradual died-off of the pancreas beta cells or insulin receptors clogged-up by fat and cholesterol.
Hallmarks of diabetes are hyperglycemia and insulin resistance.
According to the statistics, in 2017, 7.3% of Canadians aged 12 and older (roughly 2.3 million people) reported being diagnosed with diabetes.
Most common causes of diabetes are metabolic syndrome, a cluster of conditions including high blood pressure, cholesterol, and glucose, gestational diabetes, prediabetes, damage to the pancreas causes the gradual and irreversible loss of beta cells that reduce the production of insulin, and influenza a viruses
Hypertension, a condition associated with the cluster of metabolic syndrome is a medical condition associated with abnormally high blood pressure.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood and changes constantly depending on activity. However, persistent hypertension due to poor management over time can lead to diabetes and cardiovascular disease.
According to the statistics provided by the American Heart Association., nearly half of all adults in the United States are living with high blood pressure or 1 in 3 American are hypertensive.
Hypertension is leading risk factors of heart disease and stroke that cause most death in the US
The most common prevalent factors associated with the condition onset are family history, aging, being male, being overweight or obese, ethnicity, physical inactivity, unhealthy diet and medical condition such as chronic kidney disease.
Believe it or not, excessive alcohol drinking is also one of the major causes besides obesity in elevating the syndrome onset.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the management of blood pressure, researchers examined the effect of a water-soluble cranberry-based phytochemical combination with oregano, rosemary, and Rhodiola Rosea against hypertension.
According to the tested analysis, the 75% cranberry with 25% oregano combinations showed the highest antioxidant phenolics (38.9 mg/g DW) comapred to other combinations by inhibition of free radical DPPH inhibition by 73.6 %.
Furthermore, 75% cranberry and 25% Rhodiola Rosea combination had the highest alpha-glucosidase activity among the combinations.
Alpha-amyloid associated diabetes also was associated with 75% cranberry with 25% Rhodiola Rosea combination comapred to other combinations.
Additionally, anti-ACE-I inhibitory activity against the risk of hypertension was also inhibited by the 75% cranberry with 25% rosemary comapred to other combinations.
In other words, cranberry combined with other herbal medicine protects patients with diabetes and hypertension against complications by inhibiting the levels of alpha-glucosidase, alpha-amyloid, and ACE-I
Based on the results, researchers said, "The analysis of alpha-glucosidase,alpha-amylase, and ACE-I inhibitory activities suggested that inhibition depends on the phenolic profile of each unique extract and by bringing together synergistic combinations to cranberry, health beneficial functionality was enhanced".
Taken altogether, cranberry may be considered a remedy for the management of diabetes and hypertension, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Potential of cranberry-based herbal synergies for diabetes and hypertensionmanagement by Apostolidis E1, Kwon YI, Shetty K. (PubMed)
Tuesday, August 25, 2020
Dietary Patterns in the Risk of Metabolic Syndrome
A dietary pattern is the measurement of the quantity, variety, or combination of different foods and beverage in a diet as well as the frequency of the foods are habitually consumed.
Most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, high salt, and sugar.foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes are increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
On finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 y of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in the beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The western pattern has a strong and negative impact in increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels comapred to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
Most common dietary patterns are
* The traditional diet, Wikipedia wrote, "Traditional foods are foods and dishes that are passed through generations or which have been consumed many generations. Traditional foods and dishes are traditional in nature, and may have a historic precedent in a national dish, regional cuisine or local cuisine".
* The Western diet is a standard American diet (SAD) associated with high intakes of red meat, processed meat, pre-packaged and refined foods, fried foods, high-fat dairy products, high salt, and sugar.foods.
Metabolic syndrome is a cluster of conditions associated with the increased risk of cardiovascular disease and diabetes.
The health problems found in the group include too much fat around the waist, elevated blood pressure, high triglycerides, elevated blood sugar, and low HDL cholesterol.
In other words, if you have 3 of the conditions in the group, your risk of CVD and diabetes are increased substantially compared to those who have less.
According to the statistics, approximately 30% of people in the US are living with metabolic syndrome.
Believe it or not, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%.
Besides the aforementioned conditions, risks of metabolic syndrome may include age, family history, physical, inactivity, and women with polycystic ovary syndrome, epidemiologically.
As of today, treatment of metabolic syndrome commonly is prescribed medications to reduce blood pressure, cholesterol, and/or blood sugar with an aim to reduce the risk of developing further health complications and improve quality of life.
On finding a potent ingredient for the treatment of metabolic syndrome, researchers investigated the association between major dietary patterns, including several eating habits.
The cross-sectional study included a total of 425 subjects 35 to 55 y of age, using a food-frequency questionnaire in 5 dietary patterns.
Five major dietary patterns were examined by the Isfahan University of Medical Sciences, including
* A western pattern (high in sweets, butter, soda, mayonnaise, sugar, cookies, the tail of a lamb, hydrogenated fat, and eggs),
* A prudent pattern (high in fish, peas, honey, nuts, juice, dry fruits, vegetable oil, liver and organic meat, and coconuts and low in hydrogenated fat and non-leafy vegetables),
* A vegetarian pattern (high in potatoes, legumes, fruits rich in vitamin C, rice, green leafy vegetables, and fruits rich in vitamin A),
* A high-fat dairy pattern (high in high-fat yogurt and high-fat milk and low in low-fat yogurt, peas, and bread), and
* A chicken and plant pattern (high in chicken, fruits rich in vitamin A, green leafy vegetables, and mayonnaise and low in the beef, liver, and organic meat).
Based on the tested differentiation and adjusting to other confounders,
* The western pattern has a strong and negative impact in increasing triacylglycerol and blood pressure.
* The prudent pattern was positively associated a low high-density lipoprotein cholesterol levels comapred to other dietary patterns.
* However, the vegetarian dietary pattern was inversely associated with a risk of an abnormal fasting blood glucose level.
Collectively, all dietary patterns are associated with positive or negative in increasing or decreasing the risk of metabolic syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Relationship between major dietary patterns and metabolic syndrome among individuals with impaired glucose tolerance by Amini M1, Esmaillzadeh A, Shafaeizadeh S, Behrooz J, Zare M. (PubMed)
Monday, August 24, 2020
Chaste Tree Berry, the Functional Food for Treatment of Type I and II Diabetes
Chaste tree berry may have a potential in improved pancreatic islet regeneration in reduced risk of development and treatment of Type I and II diabetes, the renowned institute study postulated.
Diabetes is condition caused by insufficient insulin entering the bloodstream in regulation of glucose. The disease is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by an allergic reaction of cells in the immune system.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the study, diabetes rats induced by streptozotocin treated with extract of chaste tree berry displayed a significant effect in increased volume density of pancreatic islet as well as percentage of β-cells and size of the islet.
Dr. Oche O, the lead researcher said, "plant extracts, (exhibited) regeneration of β-cells along with β-cells repairs, in compared to non-treated diabetic control which showed complete degeneration of the islet cells".
Furthermore, the study also found that the levels of total bilirubin, direct bilirubin, and unconjugated bilirubin which are associated with diabetes were significantly lower in the treated group in comparison to control.
More important, in D-galactose induces pancreatic disorder along in the aging mouse model, treatment of Vitex agnus-castus (VAC) demonstrated potential pancreatic protective and hypoglycemic effects through improved the size of pancreatic islets decreased in aged and D-galactose groups.
In a total of 72 adult female Naval Medical Research Institute (NMRI) mice (weighing 30-35 g) divided into 6 groups of control, VAC hydroalcoholic extract, D-galactose, D-galactose + VAC hydroalcoholic extract, aged, aged + VAC hydroalcoholic extract through subcutaneous injection of D-galactose for 45 days and, VAC hydroalcoholic extract gavaged twice a day in the last 7 days. 24 h after the last drug and extract administrations, group treated with Chaste tree berry extract or combinations of the extract showed increased insulin and decreased serum glucose and in D-galactose level compared to other treatment groups.
The study also found, "Despite the size of pancreatic islets decreased in aged and D-galactose groups, ........... VAC hydroalcoholic extract has hypoglycemic and pancreatic protective effects in natural aged and aging model mice".
In fact, there is also a report indicated that oral administration of once-daily to diabetic rats for the period of 30 days of iridoid glucoside isolated from chaste tree berry may be as effective as glibenclamide, a known hypoglycemic drug, at a concentration of 50 mg/kg b.w.
Promisingly, iridoid glucoside reversed hyperglycemia-induced biochemical changes to near-normal levels.
Collectively, Chaste tree berry may be used as a functional food for the treatment of Type I and Type II diabetes through the hypoglycemic and pancreatic protective effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Pancreatic islet regeneration and some liver biochemical parameters of leaf extracts of Vitex doniana in normal and streptozotocin-induced diabetic albino rats by Oche O1, Sani I1, Chilaka NG1, Samuel NU1, Samuel A1.(PubMed)
(2) Pancreatic protective and hypoglycemic effects of Vitex agnus-castus L. fruit hydroalcoholic extract in D-galactose-induced aging mouse model by Ahangarpour A1, Oroojan AA2, Khorsandi L3, Najimi SA4.(PubMed)
(3) Antihyperglycemic effect of iridoid glucoside, isolated from the leaves of Vitex negundo in streptozotocin-induced diabetic rats with special reference to glycoprotein components by Sundaram R1, Naresh R, Shanthi P, Sachdanandam P.(PubMed)
Diabetes is condition caused by insufficient insulin entering the bloodstream in regulation of glucose. The disease is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by an allergic reaction of cells in the immune system.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the study, diabetes rats induced by streptozotocin treated with extract of chaste tree berry displayed a significant effect in increased volume density of pancreatic islet as well as percentage of β-cells and size of the islet.
Dr. Oche O, the lead researcher said, "plant extracts, (exhibited) regeneration of β-cells along with β-cells repairs, in compared to non-treated diabetic control which showed complete degeneration of the islet cells".
Furthermore, the study also found that the levels of total bilirubin, direct bilirubin, and unconjugated bilirubin which are associated with diabetes were significantly lower in the treated group in comparison to control.
More important, in D-galactose induces pancreatic disorder along in the aging mouse model, treatment of Vitex agnus-castus (VAC) demonstrated potential pancreatic protective and hypoglycemic effects through improved the size of pancreatic islets decreased in aged and D-galactose groups.
In a total of 72 adult female Naval Medical Research Institute (NMRI) mice (weighing 30-35 g) divided into 6 groups of control, VAC hydroalcoholic extract, D-galactose, D-galactose + VAC hydroalcoholic extract, aged, aged + VAC hydroalcoholic extract through subcutaneous injection of D-galactose for 45 days and, VAC hydroalcoholic extract gavaged twice a day in the last 7 days. 24 h after the last drug and extract administrations, group treated with Chaste tree berry extract or combinations of the extract showed increased insulin and decreased serum glucose and in D-galactose level compared to other treatment groups.
The study also found, "Despite the size of pancreatic islets decreased in aged and D-galactose groups, ........... VAC hydroalcoholic extract has hypoglycemic and pancreatic protective effects in natural aged and aging model mice".
In fact, there is also a report indicated that oral administration of once-daily to diabetic rats for the period of 30 days of iridoid glucoside isolated from chaste tree berry may be as effective as glibenclamide, a known hypoglycemic drug, at a concentration of 50 mg/kg b.w.
Promisingly, iridoid glucoside reversed hyperglycemia-induced biochemical changes to near-normal levels.
Collectively, Chaste tree berry may be used as a functional food for the treatment of Type I and Type II diabetes through the hypoglycemic and pancreatic protective effects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Pancreatic islet regeneration and some liver biochemical parameters of leaf extracts of Vitex doniana in normal and streptozotocin-induced diabetic albino rats by Oche O1, Sani I1, Chilaka NG1, Samuel NU1, Samuel A1.(PubMed)
(2) Pancreatic protective and hypoglycemic effects of Vitex agnus-castus L. fruit hydroalcoholic extract in D-galactose-induced aging mouse model by Ahangarpour A1, Oroojan AA2, Khorsandi L3, Najimi SA4.(PubMed)
(3) Antihyperglycemic effect of iridoid glucoside, isolated from the leaves of Vitex negundo in streptozotocin-induced diabetic rats with special reference to glycoprotein components by Sundaram R1, Naresh R, Shanthi P, Sachdanandam P.(PubMed)
Sunday, August 23, 2020
Herbal Cinnamon, The Natural Alternative for Treatment of Infertility, Scientists Say
Scientists may have found a kitchen spice which processes some underline mechanisms in enhancing the rate of fertility, some studies suggested.
Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or the cannot carry the pregnancy full term.
The syndrome affects over 5 million couples alone in the US. Because of the unawareness of treatments, only 10% seek help from professionals.
According to the statistic, about 35% of infertility is caused by the male's inability to fertilize. 35% is caused by the female's inability to conceive, 10% attributes to both, and 10 % is considered a failure with an unknown cause.
Dr, Romero Ramos R, in the study [Risk factors associated to female infertility], wrote, "There were 6 factors with statistical significance: advanced age (p < 0.001), elevated body mass index (p < 0.001), age of onset of sexual activity (p < 0.001), prior pelvic surgeries (p < 0.001), and presence of stress (p < 0.001). Other risk factors such as smoking, chemical, and radiological treatments, pelvic inflammatory disease, exercise, contraceptive use, alcohol intake, drugs, coffee, solvents, glue, and insecticides, were not significant".
In male infertility, according to a case-control study conducted by Dr. Buiatti E and colleagues, about coffee and alcohol consumption, smoking habits, x-ray exposure, usual sitting posture, drug consumption, other nonoccupational risk factors, socioeconomic status, education level, and occupational history are some of the prevalent risk factors associated to male infertility.
And, the high relative risk was associated with (a) occupation in the radioelectric industry, (b) non-sedentary clerical workers, (c) clerical work in the typographic industry, and (d) occupation in the textile industry,
Cinnamon, a kitchen spice in many cultures, may be best known for its effectiveness in reducing the levels of blood glucose in diabetics and lipid peroxidation through its antioxidant activity(4).
In a total of 45 women with Polycystic Ovary Syndrome, randomized, 26 women completed 3 months of the study, and 17 women completed the entire 6 months of the study, researchers showed,
* Application of cinnamon exerts a positive effect in the improvement of menstrual cyclicity associated with luteal phase progesterone levels and ovulatory menses without altering insulin resistance or serum androgen levels
* Cinnamaldehyde, a major chemical compound of cinnamon enhances fertility through selectively induced progesterone production and inhibits the production of testosterone and dehydroepiandrosterone in human adrenal cells.
* Further differentiation, suggested that cinnamon extract not only reduces insulin resistance in vitro and in vivo by increasing phosphatidylinositol 3-kinase activity with insulin stimulation in the insulin signaling pathway but also improves menstrual cyclicity in female induced PCOs.
Moreover, in the infertile male rat study conducted by Fırat University, long-term cinnamon bark oil(CPO) improved the effect on testicular oxidant-antioxidant balance and sperm quality with significantly decreasing the abnormal sperm rate and apoptotic germ cell count.
Interestingly, in the study to investigate the likelihood of detrimental effects of carbon tetrachloride (CCl4 ) on the male reproductive system through oxidative stress mechanism and also protective effects of cinnamon bark oil (CBO), researchers at the Firat University conducted an experiment including 28 healthy male Wistar rats.
The tested subjects were divided into four groups, seven rats in each. Group 1 received only olive oil daily; group 2 was treated with 100 mg kg(-1) CBO daily; group 3 was treated with only 0.25 ml kg(-1) CCl4 weekly, and group 4 received weekly CCl4 + daily CBO.
All administrations were made by the intragastric catheter and maintained for 10 weeks.
At the final report, researchers suggested that
* CCl4 administration caused significant decreases in body and reproductive organ weights, testicular catalase (CAT) activity, sperm motility and concentration, and significant increases in lipid peroxidation (LPO) level, abnormal sperm rate and apoptotic index along with some histopathological damages compared with the control group.
* Pretreatment of CBO following the administration of CCl4 significant improvements in absolute weights of testis and epididymis, all sperm quality parameters, LPO level, apoptotic index, and testicular histopathological structure Cl4, compared to the group given CCl4 only.
Taken altogether, Cinnamon may be effective in promoting fertility in both sexes through enhancing the menstrual cycle in women and improving sperm performance in men.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Preliminary Evidence that Cinnamon Improves Menstrual Cyclicity in Women with Polycystic Ovarian Syndrome: a Randomized Controlled Trial by Kort DH1, Lobo RA. (PubMed)
(2) Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell and sperm quality by Yüce A1, Türk G, Çeribaşi S, Sönmez M, Çiftçi M, Güvenç M.(PubMed)
(3) Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells by Iwaoka Y1, Hashimoto R, Koizumi H, Yu J, Okabe T.(PubMed)
(4) Preventive effect of cinnamon essential oil on lipid oxidation of vegetable oil by Keshvari M1, Asgary S, Jafarian-Dehkordi A, Najafi S, Ghoreyshi-Yazdi SM(PubMed)
(5) Popular #Herbs - #Dang Qui (Angelica Sinensis)
(6) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA.(PubMed)
(7) Effectiveness of cinnamon (Cinnamomum zeylanicum) bark oil in the prevention of carbon tetrachloride-induced damages on the male reproductive system by Yüce A1, Türk G, Çeribaşı S, Güvenç M, Çiftçi M, Sönmez M, Özer Kaya Ş, Çay M, Aksakal M.(PubMed)
(8) The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study by Wang JG1, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, Lobo RA. (PubMed)
(8) [Risk factors associated to female infertility].[Article in Spanish] by Romero Ramos R1, Romero Gutiérrez G, Abortes Monroy I, Medina Sánchez HG. (PubMed)
Infertility is a condition characterized by the inability of a couple to conceive after 12 months of unprotected sexual intercourse or the cannot carry the pregnancy full term.
The syndrome affects over 5 million couples alone in the US. Because of the unawareness of treatments, only 10% seek help from professionals.
According to the statistic, about 35% of infertility is caused by the male's inability to fertilize. 35% is caused by the female's inability to conceive, 10% attributes to both, and 10 % is considered a failure with an unknown cause.
Dr, Romero Ramos R, in the study [Risk factors associated to female infertility], wrote, "There were 6 factors with statistical significance: advanced age (p < 0.001), elevated body mass index (p < 0.001), age of onset of sexual activity (p < 0.001), prior pelvic surgeries (p < 0.001), and presence of stress (p < 0.001). Other risk factors such as smoking, chemical, and radiological treatments, pelvic inflammatory disease, exercise, contraceptive use, alcohol intake, drugs, coffee, solvents, glue, and insecticides, were not significant".
In male infertility, according to a case-control study conducted by Dr. Buiatti E and colleagues, about coffee and alcohol consumption, smoking habits, x-ray exposure, usual sitting posture, drug consumption, other nonoccupational risk factors, socioeconomic status, education level, and occupational history are some of the prevalent risk factors associated to male infertility.
And, the high relative risk was associated with (a) occupation in the radioelectric industry, (b) non-sedentary clerical workers, (c) clerical work in the typographic industry, and (d) occupation in the textile industry,
Cinnamon, a kitchen spice in many cultures, may be best known for its effectiveness in reducing the levels of blood glucose in diabetics and lipid peroxidation through its antioxidant activity(4).
In a total of 45 women with Polycystic Ovary Syndrome, randomized, 26 women completed 3 months of the study, and 17 women completed the entire 6 months of the study, researchers showed,
* Application of cinnamon exerts a positive effect in the improvement of menstrual cyclicity associated with luteal phase progesterone levels and ovulatory menses without altering insulin resistance or serum androgen levels
* Cinnamaldehyde, a major chemical compound of cinnamon enhances fertility through selectively induced progesterone production and inhibits the production of testosterone and dehydroepiandrosterone in human adrenal cells.
* Further differentiation, suggested that cinnamon extract not only reduces insulin resistance in vitro and in vivo by increasing phosphatidylinositol 3-kinase activity with insulin stimulation in the insulin signaling pathway but also improves menstrual cyclicity in female induced PCOs.
Moreover, in the infertile male rat study conducted by Fırat University, long-term cinnamon bark oil(CPO) improved the effect on testicular oxidant-antioxidant balance and sperm quality with significantly decreasing the abnormal sperm rate and apoptotic germ cell count.
Interestingly, in the study to investigate the likelihood of detrimental effects of carbon tetrachloride (CCl4 ) on the male reproductive system through oxidative stress mechanism and also protective effects of cinnamon bark oil (CBO), researchers at the Firat University conducted an experiment including 28 healthy male Wistar rats.
The tested subjects were divided into four groups, seven rats in each. Group 1 received only olive oil daily; group 2 was treated with 100 mg kg(-1) CBO daily; group 3 was treated with only 0.25 ml kg(-1) CCl4 weekly, and group 4 received weekly CCl4 + daily CBO.
All administrations were made by the intragastric catheter and maintained for 10 weeks.
At the final report, researchers suggested that
* CCl4 administration caused significant decreases in body and reproductive organ weights, testicular catalase (CAT) activity, sperm motility and concentration, and significant increases in lipid peroxidation (LPO) level, abnormal sperm rate and apoptotic index along with some histopathological damages compared with the control group.
* Pretreatment of CBO following the administration of CCl4 significant improvements in absolute weights of testis and epididymis, all sperm quality parameters, LPO level, apoptotic index, and testicular histopathological structure Cl4, compared to the group given CCl4 only.
Taken altogether, Cinnamon may be effective in promoting fertility in both sexes through enhancing the menstrual cycle in women and improving sperm performance in men.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Preliminary Evidence that Cinnamon Improves Menstrual Cyclicity in Women with Polycystic Ovarian Syndrome: a Randomized Controlled Trial by Kort DH1, Lobo RA. (PubMed)
(2) Effects of cinnamon (Cinnamomum zeylanicum) bark oil on testicular antioxidant values, apoptotic germ cell and sperm quality by Yüce A1, Türk G, Çeribaşi S, Sönmez M, Çiftçi M, Güvenç M.(PubMed)
(3) Selective stimulation by cinnamaldehyde of progesterone secretion in human adrenal cells by Iwaoka Y1, Hashimoto R, Koizumi H, Yu J, Okabe T.(PubMed)
(4) Preventive effect of cinnamon essential oil on lipid oxidation of vegetable oil by Keshvari M1, Asgary S, Jafarian-Dehkordi A, Najafi S, Ghoreyshi-Yazdi SM(PubMed)
(5) Popular #Herbs - #Dang Qui (Angelica Sinensis)
(6) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA.(PubMed)
(7) Effectiveness of cinnamon (Cinnamomum zeylanicum) bark oil in the prevention of carbon tetrachloride-induced damages on the male reproductive system by Yüce A1, Türk G, Çeribaşı S, Güvenç M, Çiftçi M, Sönmez M, Özer Kaya Ş, Çay M, Aksakal M.(PubMed)
(8) The effect of cinnamon extract on insulin resistance parameters in polycystic ovary syndrome: a pilot study by Wang JG1, Anderson RA, Graham GM 3rd, Chu MC, Sauer MV, Guarnaccia MM, Lobo RA. (PubMed)
(8) [Risk factors associated to female infertility].[Article in Spanish] by Romero Ramos R1, Romero Gutiérrez G, Abortes Monroy I, Medina Sánchez HG. (PubMed)
Saturday, August 22, 2020
Cranberry Protects Your Gum Against Periodontitis
Periodontitis is a serious case of gingivitis associated with gum infection that damages the soft tissue and destroys the bone that supports your teeth as a result of long-term poor oral hygiene
Periodontitis is preventable if the progression of gingivitis stages is stopped
Gingivitis is a common and mild form of periodontal disease caused by inflammation of the gingiva, leading to symptoms of irritation, redness, and swelling of the gum that lines the base of the teeth.
Gingivitis dental plaques formed around the base of the teeth are sticky biofilm of bacteria associated with the interaction of the food intake and bacteria in the mouth. Over time, if untreated, the condition can lead to periodontitis and advanced periodontitis.
At this early stage, the bone and connective tissue that hold the teeth in place are not yet affected. The problems can be reversed by more frequent and proper brushing and flossing.
Epidemiologically, risk factors induce the onset of gingivitis are smoking or chewing tobacco. diabetes and long-term use of certain medication including oral contraceptives, steroids, anticonvulsants, calcium channel blockers.
Some people under the treatment of chemotherapy may also experience symptoms of gingivitis.
The Colgate Professional in the examined the symptoms advised that if you have experienced some of the symptoms that do not heal themselves in a short time, such as puffy or swollen, or tender, bleeding during brushing or flossing,... and constant bad breath or a bad taste in your mouth, you may have gingivitis.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of periodontitis, researchers examined the effect of cranberry and rice extracts as a potent gingipain inhibitor.
Based on the tested analysis, cranberry and rice extracts interfere with gingipain activity that causes the slow down the progression of adult periodontitis.
Furthermore, the extracts prevented the growth and biofilm formation of periodontal pathogens induced the onset of periodontitis.
Moreover, the extracts also inhibited a broad spectrum of host proteases in the induction of undesirable side effects
As of today, the ideal gingipain inhibitor has yet to be discovered, however, cranberry and rice extracts may be a promising gingipain inhibitor comapred to gingipain N-terminal pro domains, synthetic compounds, antibiotics, antiseptics, antibodies, and bacteria which may induce undesirable side effects
The results strongly suggested that cranberry promotes oral health by inhibiting the onset and progression of periodontitis through its anti-bacterial activity
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of periodontitis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
periodontitis
(1) Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases by Olsen I1, Potempa J. (PubMed)
Periodontitis is preventable if the progression of gingivitis stages is stopped
Gingivitis is a common and mild form of periodontal disease caused by inflammation of the gingiva, leading to symptoms of irritation, redness, and swelling of the gum that lines the base of the teeth.
Gingivitis dental plaques formed around the base of the teeth are sticky biofilm of bacteria associated with the interaction of the food intake and bacteria in the mouth. Over time, if untreated, the condition can lead to periodontitis and advanced periodontitis.
At this early stage, the bone and connective tissue that hold the teeth in place are not yet affected. The problems can be reversed by more frequent and proper brushing and flossing.
Epidemiologically, risk factors induce the onset of gingivitis are smoking or chewing tobacco. diabetes and long-term use of certain medication including oral contraceptives, steroids, anticonvulsants, calcium channel blockers.
Some people under the treatment of chemotherapy may also experience symptoms of gingivitis.
The Colgate Professional in the examined the symptoms advised that if you have experienced some of the symptoms that do not heal themselves in a short time, such as puffy or swollen, or tender, bleeding during brushing or flossing,... and constant bad breath or a bad taste in your mouth, you may have gingivitis.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of periodontitis, researchers examined the effect of cranberry and rice extracts as a potent gingipain inhibitor.
Based on the tested analysis, cranberry and rice extracts interfere with gingipain activity that causes the slow down the progression of adult periodontitis.
Furthermore, the extracts prevented the growth and biofilm formation of periodontal pathogens induced the onset of periodontitis.
Moreover, the extracts also inhibited a broad spectrum of host proteases in the induction of undesirable side effects
As of today, the ideal gingipain inhibitor has yet to be discovered, however, cranberry and rice extracts may be a promising gingipain inhibitor comapred to gingipain N-terminal pro domains, synthetic compounds, antibiotics, antiseptics, antibodies, and bacteria which may induce undesirable side effects
The results strongly suggested that cranberry promotes oral health by inhibiting the onset and progression of periodontitis through its anti-bacterial activity
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of periodontitis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
periodontitis
(1) Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases by Olsen I1, Potempa J. (PubMed)
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