Scientists may have found a natural whole food with the potential to treat hyperlipidemia without inducing any side effects, some studies suggested.
Cholesterol, the natural ingredient produced in the liver plays an important role in stimulating the production of vitamin D, steroid hormones, and bile acids and maintaining healthy cell membranes.
Hyperlipidemia is a condition characterized by abnormally elevated levels of cholesterol in the plasma of the blood.
The causes of hyperlipidemia are unknown. However, an unhealthy diet with a lot of unsaturated fat and trans fat is associated with the early onset of the disease. Foods such as cheese egg yolks fried and processed foods and red meat have found to increase blood cholesterol, long-term intake of such foods in great amount have been found to increase the risk of hyperlipidemia, epidemiological studies found.
The Beni-Suef University, in the study to determine the development of obesity in response to a high-fat diet (HFD) an Egyptian Herbal mixture formulation (HMF), including fennel, showed, "feeding HFD diet significantly increased final body weight, triglycerides (TG), total cholesterol, & LDL concentration compared with controls, while significantly decreasing HD".
Hyperlipidemia is a lifelong condition that is treatable.
Dr. Robert B. Kelly at the Fairview Hospital/Cleveland Clinic Family Medicine Residency Program in the article "The most beneficial changes result from reducing intake of saturated and trans fats; increasing intake of polyunsaturated and monounsaturated fats; fortifying foods with plant stanols or sterols; isocalorically adding tree nuts to the diet; consuming one or two alcoholic drinks per day; and adopting a Portfolio, Mediterranean, low-carbohydrate, or low-fat diet. Smaller but still beneficial effects result from reducing intake of dietary cholesterol, increasing intake of soluble fiber and soy protein, and eating fatty marine fish or taking marine-derived omega-3 fatty acid supplements".
Therefore by changing the diet pattern and engaging regular physical exercise are the fundamental
options that not only can prevent the onset of the condition, particularly in people who are at a higher risk of hyperlipidemia and also treat high blood cholesterol in patients who already have the condition.
Fennel (Foeniculum vulgare) is a plant species of a genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The plant has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle, and relieve PMS.
In the study to examine the effect of the aqueous extract of fennel in the reduced risk of hyperlipidemia, researchers conducted an experiment in Triton WR-1339 induced hyperlipidemia in mice.
Mice treated with the extract at different doses displays a significant reduction of cholesterol, triglycerides, LDL-cholesterol, and apolipoprotein-B decreased by 40%, 23%, 61%, and 61%, respectively.
Further analysis, the application also increased the levels of HDL-cholesterol and apolipoprotein A1 by 85% and 58%, respectively
According to the Mashhad University of Medical Sciences which also conducted a study to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles, in sixty eligible postmenopausal women, randomly assigned into the fennel and placebo groups.
Measurement of total blood cholesterol, cholesterol fractions, and triglycerides was tested at the baseline, and after a three-month follow-up.
At the end of 3 months, blood profiled withdrawn from the women suggested
* There are no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol(LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups.
* Fennel treated group demonstrates a significant borderline improvement for HDL-C and triglyceride, compared to the placebo group.
Additional differentiation of the process of the double-blind, randomized, and placebo-controlled trial, researchers suggested that longer durations, higher doses, and larger sample sizes are recommended to validate the results.
These results indicated that the intake of foods for the treatment of conditions or diseases must be on a long-term basis. The times of 3 months may be too short for foods to exert their potential effects.
Taken all together, fennel may be considered a functional food for the prevention and treatment of hyperlipidemia. Intake of fennel should be increased gradually for the food to reach its antihyperlipidemic stage, a longer duration may be needed. In other words, please be patient.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial by Afiat M1, Amini E2, Ghazanfarpour M3, Nouri B4, Mousavi MS5, Babakhanian M6, Rakhshandeh H(PubMed)
(3) Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats by Amin KA1, Nagy M(PubMed)
Tuesday, September 8, 2020
Monday, September 7, 2020
Herbal Bilberry, The Best Functional Food For Nonalcoholic Fatty Liver Disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is a type of noninflammatory fatty liver disease caused by fat accumulated in the liver other than excessive alcohol consumption.
People who have an accumulation of triglycerides within hepatocytes that exceeds 5% of liver weight are considered to have nonalcoholic fatty liver disease.
According to the statistics, nonalcoholic fatty liver disease (NAFLD) has risen rapidly over the past few decades and become the most common cause of chronic liver disease in the developing world. The disease affects between 17-30% of the population in Western countries and 2-4% worldwide.
Epidemiologically. obesity, type II diabetes, dyslipidemia, and insulin resistance are the well-known primary causes of NAFLD.
The findings strongly suggested that NAFLD is a geographically related disease associated with dietary patterns.
Dr. Alanna McCarthy, the lead scientist in the examination of diet pattern in the risk NAFLD wrote, "Non-alcoholic fatty liver disease (NAFLD) is a serious consequence of high-fat diet intake and currently affects approximately one-third of the world’s entire population".
And, "Recent evidence suggests that patients with NAFLD have a higher incidence of cardiovascular disease compared to the general population. However, little is known about the link between NAFLD and pathological cardiac remodeling leading to heart disease".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find natural prevention and treatment of non-alcoholic fatty liver disease (NAFLD), researchers investigated the effects of anthocyanin supplementation on insulin resistance and liver injury biomarkers in patients.
74 subjects with NAFLD included in the study were divided into 2 groups in this double-blind, randomized study. Patients received either purified anthocyanin (320 mg/d) derived from bilberry and black currant or placebo for 12 weeks.
During the experiment, the anthocyanin group exhibited significantly decreased in plasma alanine aminotransferase, cytokeratin-18 M30 fragment, and myeloperoxidase, the biomarkers associated with NAFLD, compared to controls.
Compared to the baseline, the anthocyanin group significantly decreased in fasting blood glucose and homeostasis model assessment for insulin resistance, however, these differences were not significant relative to placebo controls.
Not surprisingly, anthocyanin supplementation significantly decreased the 2-hour loading glucose level compared to control, according to the oral glucose tolerance test.
Based on the findings, researchers said, "A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients".
Furthermore, according to the results from the study of ApoE(∗)3Leiden mice fed a Western-type cholesterol-containing diet without (HC) or with 0.1% (w/w) Mirtoselect (HCM), an anthocyanin-rich bilberry extract for 20weeks on diet-induced NASH, Mirtoselect treatment group showed an attenuated HC-induced hepatic steatosis and reduced hepatic cholesteryl ester content.
Furthermore, injection of Mirtoselect also exerted local anti-inflammatory effects in the liver by reduced inflammatory cell clusters and neutrophil infiltration in HCM.
In other words, HCM protected the liver against HC diet significantly induced hepatic expression of pro-inflammatory and pro-fibrotic genes associated with the onset of NAFLD.
Dr. Morrison MC, the lead scientist, after taking other factors into account wrote, "Mirtoselect attenuates the development of NASH, reducing hepatic lipid accumulation, inflammation, and fibrosis, possibly mediated by local anti-inflammatory effects associated with reduced accumulation and crystallization of intrahepatic free cholesterol".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the treatment of nonalcoholic fatty liver disease, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease by Zhang PW1, Chen FX, Li D, Ling WH, Guo HH. (PubMed)
(2) Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice by Morrison MC1, Liang W2, Mulder P2, Verschuren L2, Pieterman E2, Toet K2, Heeringa P3, Wielinga PY2, Kooistra T2, Kleemann R. (PubMed)
(3) High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease and Cardiac Physiology in Mice by
Alanna McCarthy and Stephen Luckey. (Faseb Journal)
People who have an accumulation of triglycerides within hepatocytes that exceeds 5% of liver weight are considered to have nonalcoholic fatty liver disease.
According to the statistics, nonalcoholic fatty liver disease (NAFLD) has risen rapidly over the past few decades and become the most common cause of chronic liver disease in the developing world. The disease affects between 17-30% of the population in Western countries and 2-4% worldwide.
Epidemiologically. obesity, type II diabetes, dyslipidemia, and insulin resistance are the well-known primary causes of NAFLD.
The findings strongly suggested that NAFLD is a geographically related disease associated with dietary patterns.
Dr. Alanna McCarthy, the lead scientist in the examination of diet pattern in the risk NAFLD wrote, "Non-alcoholic fatty liver disease (NAFLD) is a serious consequence of high-fat diet intake and currently affects approximately one-third of the world’s entire population".
And, "Recent evidence suggests that patients with NAFLD have a higher incidence of cardiovascular disease compared to the general population. However, little is known about the link between NAFLD and pathological cardiac remodeling leading to heart disease".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find natural prevention and treatment of non-alcoholic fatty liver disease (NAFLD), researchers investigated the effects of anthocyanin supplementation on insulin resistance and liver injury biomarkers in patients.
74 subjects with NAFLD included in the study were divided into 2 groups in this double-blind, randomized study. Patients received either purified anthocyanin (320 mg/d) derived from bilberry and black currant or placebo for 12 weeks.
During the experiment, the anthocyanin group exhibited significantly decreased in plasma alanine aminotransferase, cytokeratin-18 M30 fragment, and myeloperoxidase, the biomarkers associated with NAFLD, compared to controls.
Compared to the baseline, the anthocyanin group significantly decreased in fasting blood glucose and homeostasis model assessment for insulin resistance, however, these differences were not significant relative to placebo controls.
Not surprisingly, anthocyanin supplementation significantly decreased the 2-hour loading glucose level compared to control, according to the oral glucose tolerance test.
Based on the findings, researchers said, "A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients".
Furthermore, according to the results from the study of ApoE(∗)3Leiden mice fed a Western-type cholesterol-containing diet without (HC) or with 0.1% (w/w) Mirtoselect (HCM), an anthocyanin-rich bilberry extract for 20weeks on diet-induced NASH, Mirtoselect treatment group showed an attenuated HC-induced hepatic steatosis and reduced hepatic cholesteryl ester content.
Furthermore, injection of Mirtoselect also exerted local anti-inflammatory effects in the liver by reduced inflammatory cell clusters and neutrophil infiltration in HCM.
In other words, HCM protected the liver against HC diet significantly induced hepatic expression of pro-inflammatory and pro-fibrotic genes associated with the onset of NAFLD.
Dr. Morrison MC, the lead scientist, after taking other factors into account wrote, "Mirtoselect attenuates the development of NASH, reducing hepatic lipid accumulation, inflammation, and fibrosis, possibly mediated by local anti-inflammatory effects associated with reduced accumulation and crystallization of intrahepatic free cholesterol".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the treatment of nonalcoholic fatty liver disease, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease by Zhang PW1, Chen FX, Li D, Ling WH, Guo HH. (PubMed)
(2) Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice by Morrison MC1, Liang W2, Mulder P2, Verschuren L2, Pieterman E2, Toet K2, Heeringa P3, Wielinga PY2, Kooistra T2, Kleemann R. (PubMed)
(3) High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease and Cardiac Physiology in Mice by
Alanna McCarthy and Stephen Luckey. (Faseb Journal)
Sunday, September 6, 2020
Bromelain, the Potential Treatment of Chronic Rhinosinusitis
Rhinosinusitis (RS) is a condition associated with the inflammation of the sinuses and nasal cavity.
Sinusitis is an inflammation of the paranasal sinuses that causes a headache as a result of exposure to a cold or flu virus, or an allergic reaction to pollen, mold, dust or smoke.
Sinusitis affects 37 million people each year.
Other symptoms of RS include nasal congestion or obstruction, facial or dental pain, purulent rhinorrhea, postnasal drainage, headache, and cough.
Some patients may also experience symptoms of fever, fatigue, hyposmia, ear fullness or pressure, voice changes, epiphora, fever, and psychological effects and fatigue.
If you have some of the above symptoms that last more than 12 weeks, you may have chronic rhinosinusitis,
If you experience some of the aforementioned symptoms without a cold or flu, you may have rhinosinusitis. Conventionally, most cases of bacterial rhinosinusitis (BRS) are treated by antibiotics.
In viral rhinosinusitis (VRS), medication focus on reducing symptoms and improving quality of life.
Out of many risk factors involved in the onset of the condition, some researchers suggested that people with an immune deficiency may be vulnerable to rhinosinusitis developing.
Dr. Sergio E. Chiarella, the lead scientist wrote, "CRS is a common disease; in those patients with frequent exacerbations or who are refractory to treatment, an immunodeficiency evaluation should be considered. Treatment includes vaccination, antibiotic therapy, immunoglobulin replacement, and surgery".
More precisely, people who are using immune suppressants or weakened and immature immune systems are at an increased risk of rhinosinusitis.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for the treatment of an inflammatory condition associated with sinuses and nasal cavity, researchers examined the bromelain effects on patients with chronic rhinosinusitis (CRS).
40 patients including 20 patients were given bromelain 500 mg tablet twice daily for 30 days, and 20 controls enrolled in the study.
According to the observation in the turbinate and ethmoid mucosas and in the serum of both the groups, bromelain showed significant anti-inflammatory activity in paranasal sinus pathologies.
In other words, the efficacy of bromelain anti chronic rhinosinusitis was attributed to its function in distribution evenly in the sinuses and nasal cavity.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of chronic rhinosinusitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis by Passali D1, Passali GC2, Bellussi LM1, Sarafoleanu C3, Loglisci M1, Manea C3, Iosif C4, Passali FM. (PubMed)
(2) Alternative therapies for chronic rhinosinusitis: A review by Griffin AS1, Cabot P, Wallwork B, Panizza B. (PubMed)
(3) Immune deficiency in chronic rhinosinusitis: screening and treatment by Sergio E. Chiarella and Leslie C. Grammer. (PMC)
Sinusitis is an inflammation of the paranasal sinuses that causes a headache as a result of exposure to a cold or flu virus, or an allergic reaction to pollen, mold, dust or smoke.
Sinusitis affects 37 million people each year.
Other symptoms of RS include nasal congestion or obstruction, facial or dental pain, purulent rhinorrhea, postnasal drainage, headache, and cough.
Some patients may also experience symptoms of fever, fatigue, hyposmia, ear fullness or pressure, voice changes, epiphora, fever, and psychological effects and fatigue.
If you have some of the above symptoms that last more than 12 weeks, you may have chronic rhinosinusitis,
If you experience some of the aforementioned symptoms without a cold or flu, you may have rhinosinusitis. Conventionally, most cases of bacterial rhinosinusitis (BRS) are treated by antibiotics.
In viral rhinosinusitis (VRS), medication focus on reducing symptoms and improving quality of life.
Out of many risk factors involved in the onset of the condition, some researchers suggested that people with an immune deficiency may be vulnerable to rhinosinusitis developing.
Dr. Sergio E. Chiarella, the lead scientist wrote, "CRS is a common disease; in those patients with frequent exacerbations or who are refractory to treatment, an immunodeficiency evaluation should be considered. Treatment includes vaccination, antibiotic therapy, immunoglobulin replacement, and surgery".
More precisely, people who are using immune suppressants or weakened and immature immune systems are at an increased risk of rhinosinusitis.
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
With an aim to find a natural compound for the treatment of an inflammatory condition associated with sinuses and nasal cavity, researchers examined the bromelain effects on patients with chronic rhinosinusitis (CRS).
40 patients including 20 patients were given bromelain 500 mg tablet twice daily for 30 days, and 20 controls enrolled in the study.
According to the observation in the turbinate and ethmoid mucosas and in the serum of both the groups, bromelain showed significant anti-inflammatory activity in paranasal sinus pathologies.
In other words, the efficacy of bromelain anti chronic rhinosinusitis was attributed to its function in distribution evenly in the sinuses and nasal cavity.
Taken altogether, bromelain may be considered supplements for the prevention and treatment of chronic rhinosinusitis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis by Passali D1, Passali GC2, Bellussi LM1, Sarafoleanu C3, Loglisci M1, Manea C3, Iosif C4, Passali FM. (PubMed)
(2) Alternative therapies for chronic rhinosinusitis: A review by Griffin AS1, Cabot P, Wallwork B, Panizza B. (PubMed)
(3) Immune deficiency in chronic rhinosinusitis: screening and treatment by Sergio E. Chiarella and Leslie C. Grammer. (PMC)
Saturday, September 5, 2020
Herbal Angelica, Processes Anti-inflammatory Potency in Vitro
Inflammation is the natural response of the immune system macrophages, the first line of defense in stimulating the production of inflammatory cytokines to protect our body against the infection caused by foreign microorganisms during the acute phase of body damage and injury.
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.
Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nervous system, the immune first line of defense stimulates the production of blood platelets to the cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.
Acute inflammation usually receded after a few days or weeks depending on the size and damage.
However, people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
The most common symptoms of acute inflammation occurred with a short period of time such as hours is pain, redness, immobility, swelling, and heat.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
Chronic inflammation is the result of the immune system's inability to kill off all the microorganisms participated in the acute phase of infection, leading to the forming of autoimmune and chronic inflammatory diseases such as RA and diabetes.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.
Diseases associated with chronic inflammation asthma are chronic peptic ulcer, tuberculosis, rheumatoid arthritis, and periodontitis.
On finding a natural ingredient for the prevention and treatment of diseases associated with chronic inflammation, scientists compared the anti-inflammatory activity of Chinese herbal extracts, Drynaria baronii (DB), Angelica sinensis (AS), and Cornus officinalis Sieb. et Zucc(CO).
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the tested analysis,
* DB, AS and CO inhibited nitric oxide (NO) production by lipopolysaccharide (LPS)-activated mouse macrophage-like RAW264.7 cells by inhibition of inducible NO synthase (iNOS) expression at both protein and mRNA levels.
* Furthermore, DB, AS and CO dose-dependently scavenged the NO radical produced by NOC-7 (a nitric oxide (NO)).
* Moreover, DB and CO effectively inhibited the PGE(2) production by LPS-stimulated RAW264.7 cells, although the extent of inhibition of PGE(2) production was slightly lower than that of NO production.
* More importantly, DB, AS and CO inhibited cyclooxygenase (COX)-2 expression involved in the initiation of inflammation at both protein and mRNA levels, compared to much lesser extents as compared with that for iNOS expression
* Finally, AS only marginally inhibited the LPS-stimulated PGE(2) production
Taken altogether, Danggui may be considered an anti-inflammatory remedy for the treatment of chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells by Chu Q1, Hashimoto K, Satoh K, Wang Q, Sakagami H. (PubMed)
Truly, the main focus of inflammation is to repair damage and injury.
Most cases of infection associated with inflammation are stopped at the acute phase. The wound or injury is slowly recovered.
Acute inflammation is a natural response of the immune system to protect the human body against harmful stimuli and pathogens.
Acute information is the first phase of injection. At this phase, after sensing the body injury by the central nervous system, the immune first line of defense stimulates the production of blood platelets to the cover the site of damage and pro-inflammatory to kill off pathogens that try to enter the body through the wound or damaged tissue.
Acute inflammation usually receded after a few days or weeks depending on the size and damage.
However, people with a weakened immune system, acute inflammatory progression cannot be stopped due to the inability of the immune system to destroy all invaders, which may lead to low-grade chronic inflammation.
The most common symptoms of acute inflammation occurred with a short period of time such as hours is pain, redness, immobility, swelling, and heat.
Any inflammation that lasts more than 3 months is considered chronic inflammation.
Chronic inflammation is the result of the immune system's inability to kill off all the microorganisms participated in the acute phase of infection, leading to the forming of autoimmune and chronic inflammatory diseases such as RA and diabetes.
Anti-inflammation is the process that inhibits inflammation or swelling without affecting the immune property to curb foreign pathogens.
Diseases associated with chronic inflammation asthma are chronic peptic ulcer, tuberculosis, rheumatoid arthritis, and periodontitis.
On finding a natural ingredient for the prevention and treatment of diseases associated with chronic inflammation, scientists compared the anti-inflammatory activity of Chinese herbal extracts, Drynaria baronii (DB), Angelica sinensis (AS), and Cornus officinalis Sieb. et Zucc(CO).
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen the heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
According to the tested analysis,
* DB, AS and CO inhibited nitric oxide (NO) production by lipopolysaccharide (LPS)-activated mouse macrophage-like RAW264.7 cells by inhibition of inducible NO synthase (iNOS) expression at both protein and mRNA levels.
* Furthermore, DB, AS and CO dose-dependently scavenged the NO radical produced by NOC-7 (a nitric oxide (NO)).
* Moreover, DB and CO effectively inhibited the PGE(2) production by LPS-stimulated RAW264.7 cells, although the extent of inhibition of PGE(2) production was slightly lower than that of NO production.
* More importantly, DB, AS and CO inhibited cyclooxygenase (COX)-2 expression involved in the initiation of inflammation at both protein and mRNA levels, compared to much lesser extents as compared with that for iNOS expression
* Finally, AS only marginally inhibited the LPS-stimulated PGE(2) production
Taken altogether, Danggui may be considered an anti-inflammatory remedy for the treatment of chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells by Chu Q1, Hashimoto K, Satoh K, Wang Q, Sakagami H. (PubMed)
Friday, September 4, 2020
Cranberry, the Anti Cardiovascular Disease Remedy
Cardioprotection is an action that contributes to the protection of heart and blood vessels integrity against damage or injury, including heart diseases, and stroke.
In other words, cardioprotection is a process in which substances or medicines are used including an herbal remedy to protect heart muscle tissues against ischemic insult and deoxygenation injury.
Cardiovascular diseases (CVD) are a class of conditions associated with the dysfunction of the arteries and heart, affecting the heart functioning.
According to the statistics provided by the CDC, heart disease is the leading cause of death for both men and women. Men are associated with 1/2 of the deaths due to heart disease in 2015 were in men, comapred to women.
Believe it or not, more than 63),000 Americans die from heart disease each year or 1 in every 4 deaths are caused by heart disease.
On another hand, stroke is a medical condition caused by poor blood flow to the brain, leading to brain cell death in the affected region.
The most common types of stroke are ischemic stroke associated with the obstruction of a blood vessel supplying blood to the brain and hemorrhagic stroke associated with small blood vessel ruptures. Most common cause of stroke is unmanaged high blood pressure.
The US statistics indicated that stroke is the leading cause of long-term disability in the United States. Each year, more than 79o,000 people suffer a stroke, including 600,000 of first attacks, and 185,000 recurrent attacks.
Coronary artery disease caused by narrowing of the arteries, heart attack, abnormal heart rhythms, or arrhythmias and stroke is the most common type of cardiovascular disease found in the Western world.
The most common symptoms of CVD include persistent fatigue, shortness of breath, irregular heartbeat, chest pain, and fainting.
If you have some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the CVD possibility.
The exact causes of cardiovascular diseases are unidentified. However, according to epidemiological studies, the most prevalent factors that cause an increased risk of CVD are an unhealthy lifestyle correlated to the promotion of the Western diet.
Dr. Oikonomou E and colleagues in the joint study led by the National and Kapodistrian University of Athens wrote, "... Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001)".
And, "an unhealthy Western type of diet is associated with the severity of coronary artery lesions in patients with stable CAD. These findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD".
The results strongly suggested by lifestyle change have a strong implication in the prevention of CVD.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of heart disease and stroke, researchers examined the efficacy of cranberry supplementation on cardiovascular disease metabolic risk factors in adult populations.
The systematic review is conducted by searching the databases of PubMed, Scopus, Web of Science, and Google Scholar up to June 2018, to identify randomized controlled trials investigating the effect of cranberry supplementation on cardiovascular metabolic risk factors.
According to the results from the review of the pooled effect size, cranberry administration decreased the risk of CVD by significantly reducing systolic blood pressure and body mass index.
However, other parameters associated with the metabolic risks such as triacylglycerol, total cholesterol, low-density lipoprotein, high-density lipoprotein, fasting plasma glucose, fasting insulin, homeostasis model assessment of insulin resistance, diastolic blood pressure, waist circumference, C-reactive protein, and intercellular adhesion molecule were not changed much after cranberry administration.
Furthermore, the most reduction of SBP was more pronounced in patients with age ≥50 comapred to the younger age group.
Moreover, comapred to no change in supplemental administration, there was also a significant increase in high-density lipoprotein concentrations in subgroups with subjects <50 mean age and triacylglycerol levels in subsets with cranberry administered in juice form.
Based on the findings, researchers concluded. " cranberry supplementation may be effective in managing systolic blood pressure, body mass index and high-density lipoprotein in younger adults. Further high-quality studies are needed to confirm these results.".
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of CVD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of cranberry on cardiovascular metabolic risk factors: A systematic review and meta-analysis by Pourmasoumi M1, Hadi A2, Najafgholizadeh A3, Joukar F4, Mansour-Ghanaei F. (PubMed)
(2) Western Dietary Pattern Is Associated With Severe Coronary Artery Disease by Oikonomou E1, Psaltopoulou T2, Georgiopoulos G1, Siasos G1,3, Kokkou E1, Antonopoulos A1, Vogiatzi G1, Tsalamandris S1, Gennimata V1, Papanikolaou A1, Tousoulis D. (PubMed)
In other words, cardioprotection is a process in which substances or medicines are used including an herbal remedy to protect heart muscle tissues against ischemic insult and deoxygenation injury.
Cardiovascular diseases (CVD) are a class of conditions associated with the dysfunction of the arteries and heart, affecting the heart functioning.
According to the statistics provided by the CDC, heart disease is the leading cause of death for both men and women. Men are associated with 1/2 of the deaths due to heart disease in 2015 were in men, comapred to women.
Believe it or not, more than 63),000 Americans die from heart disease each year or 1 in every 4 deaths are caused by heart disease.
On another hand, stroke is a medical condition caused by poor blood flow to the brain, leading to brain cell death in the affected region.
The most common types of stroke are ischemic stroke associated with the obstruction of a blood vessel supplying blood to the brain and hemorrhagic stroke associated with small blood vessel ruptures. Most common cause of stroke is unmanaged high blood pressure.
The US statistics indicated that stroke is the leading cause of long-term disability in the United States. Each year, more than 79o,000 people suffer a stroke, including 600,000 of first attacks, and 185,000 recurrent attacks.
Coronary artery disease caused by narrowing of the arteries, heart attack, abnormal heart rhythms, or arrhythmias and stroke is the most common type of cardiovascular disease found in the Western world.
The most common symptoms of CVD include persistent fatigue, shortness of breath, irregular heartbeat, chest pain, and fainting.
If you have some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the CVD possibility.
The exact causes of cardiovascular diseases are unidentified. However, according to epidemiological studies, the most prevalent factors that cause an increased risk of CVD are an unhealthy lifestyle correlated to the promotion of the Western diet.
Dr. Oikonomou E and colleagues in the joint study led by the National and Kapodistrian University of Athens wrote, "... Western dietary pattern (increased intake of fat, red meat, and carbohydrates and minimal consumption of fruits and green leafy vegetables) was predictive of severe CAD (area under the curve: 0.73, 95% confidence intervals: 0.64-0.83, P < .001)".
And, "an unhealthy Western type of diet is associated with the severity of coronary artery lesions in patients with stable CAD. These findings highlight the role of dietary patterns when estimating cardiovascular risk for the management of patients with CAD".
The results strongly suggested by lifestyle change have a strong implication in the prevention of CVD.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of heart disease and stroke, researchers examined the efficacy of cranberry supplementation on cardiovascular disease metabolic risk factors in adult populations.
The systematic review is conducted by searching the databases of PubMed, Scopus, Web of Science, and Google Scholar up to June 2018, to identify randomized controlled trials investigating the effect of cranberry supplementation on cardiovascular metabolic risk factors.
According to the results from the review of the pooled effect size, cranberry administration decreased the risk of CVD by significantly reducing systolic blood pressure and body mass index.
However, other parameters associated with the metabolic risks such as triacylglycerol, total cholesterol, low-density lipoprotein, high-density lipoprotein, fasting plasma glucose, fasting insulin, homeostasis model assessment of insulin resistance, diastolic blood pressure, waist circumference, C-reactive protein, and intercellular adhesion molecule were not changed much after cranberry administration.
Furthermore, the most reduction of SBP was more pronounced in patients with age ≥50 comapred to the younger age group.
Moreover, comapred to no change in supplemental administration, there was also a significant increase in high-density lipoprotein concentrations in subgroups with subjects <50 mean age and triacylglycerol levels in subsets with cranberry administered in juice form.
Based on the findings, researchers concluded. " cranberry supplementation may be effective in managing systolic blood pressure, body mass index and high-density lipoprotein in younger adults. Further high-quality studies are needed to confirm these results.".
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of CVD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The effects of cranberry on cardiovascular metabolic risk factors: A systematic review and meta-analysis by Pourmasoumi M1, Hadi A2, Najafgholizadeh A3, Joukar F4, Mansour-Ghanaei F. (PubMed)
(2) Western Dietary Pattern Is Associated With Severe Coronary Artery Disease by Oikonomou E1, Psaltopoulou T2, Georgiopoulos G1, Siasos G1,3, Kokkou E1, Antonopoulos A1, Vogiatzi G1, Tsalamandris S1, Gennimata V1, Papanikolaou A1, Tousoulis D. (PubMed)
Thursday, September 3, 2020
Herbal Ashwagandha Protects the Heart Tissues Against Cardio-Toxicity
Cardiotoxicity is a condition caused by toxin accumulated in the heart that leads to damage to the heart muscle.
Cardiotoxicity reduced the heart pumping blood capability, leading to a decrease in oxygen-rich blood to nourish the body tissues and organs.
The most common symptoms of cardiotoxicity, are tiredness fatigue, chronic cough, water retention, and shortness of breath.
If you have experienced some of the aforementioned symptoms that can be healed within a week or 2, please check with your doctor to rule out the possibility.
The most common causes of cardiotoxicity are associated with patients receiving chemotherapy and the intake of certain medications. However, infection, excessive alcohol consumption, medical conditions such as diabetes and thyroid disease, high blood pressure, and thiamine, and Vitamin B deficiency have also been found to induce cardiotoxicity.
Cardiomyopathy is a severe case of cardiotoxicity.
Cardiomyopathy in most occurs in patients under chemotherapy. However, a group of diseases or disorders can also lead to damaged heart muscle. Injury to the heart muscle may induce cardiomyopathy, including viruses - such as human immunodeficiency virus (HIV), infection, long-standing high blood pressure, chronic or long-term alcohol use, and diabetes.
Conventionally, treatment of cardiotoxicity depending on the cause of the disease may include
* Beta-blockers, for the improvement of the blood flow and reduction of palpitations, arrhythmias, and high blood pressure.
*ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow.
* Diuretics, by getting rid of excess fluids that reduce heart function in blood pumping
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of cardiovascular diseases, researchers examined the protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.
According to the results of the experiment, doxorubicin (10 mg/kg) -induced cardiac toxicity in male Wistar rats showed an increase of necrosis and apoptosis in heart tissues.
Furthermore, the elevation of malondialdehyde and protein carbonyl levels and catalase activity associated with the expression of oxidative stress also wee found in the doxorubicin (10 mg/kg) rats.
The doxorubicin (10 mg/kg) rats also exhibited depletion of total antioxidant capacity and of superoxide dismutase level in cardiac tissues, accompanied by the increases of myeloperoxidase activity, total calcium content, and the expression of Bcl-2 protein in heart tissues.
Most importantly, all parameters induced by the injection of doxorubicin alterations were effectively attenuated by the administration of the purified standardized extract (1.5% withanolides; manufactured by Idea Sphere Inc., American Fork, UT, USA) of Withania somnifera (300 mg/kg).
Based on the evidence, researchers said, "Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug".
Taken altogether, Ashwagandha may be considered supplements for the prevention and treatment of Cardiotoxicity induced by medications, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats by Hamza A1, Amin A, Daoud S. (PubMed)
Cardiotoxicity reduced the heart pumping blood capability, leading to a decrease in oxygen-rich blood to nourish the body tissues and organs.
The most common symptoms of cardiotoxicity, are tiredness fatigue, chronic cough, water retention, and shortness of breath.
If you have experienced some of the aforementioned symptoms that can be healed within a week or 2, please check with your doctor to rule out the possibility.
The most common causes of cardiotoxicity are associated with patients receiving chemotherapy and the intake of certain medications. However, infection, excessive alcohol consumption, medical conditions such as diabetes and thyroid disease, high blood pressure, and thiamine, and Vitamin B deficiency have also been found to induce cardiotoxicity.
Cardiomyopathy is a severe case of cardiotoxicity.
Cardiomyopathy in most occurs in patients under chemotherapy. However, a group of diseases or disorders can also lead to damaged heart muscle. Injury to the heart muscle may induce cardiomyopathy, including viruses - such as human immunodeficiency virus (HIV), infection, long-standing high blood pressure, chronic or long-term alcohol use, and diabetes.
Conventionally, treatment of cardiotoxicity depending on the cause of the disease may include
* Beta-blockers, for the improvement of the blood flow and reduction of palpitations, arrhythmias, and high blood pressure.
*ACE inhibitors induce (widen) the arterial dilation and improvement of the blood flow.
* Diuretics, by getting rid of excess fluids that reduce heart function in blood pumping
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, the Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the prevention of cardiovascular diseases, researchers examined the protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats.
According to the results of the experiment, doxorubicin (10 mg/kg) -induced cardiac toxicity in male Wistar rats showed an increase of necrosis and apoptosis in heart tissues.
Furthermore, the elevation of malondialdehyde and protein carbonyl levels and catalase activity associated with the expression of oxidative stress also wee found in the doxorubicin (10 mg/kg) rats.
The doxorubicin (10 mg/kg) rats also exhibited depletion of total antioxidant capacity and of superoxide dismutase level in cardiac tissues, accompanied by the increases of myeloperoxidase activity, total calcium content, and the expression of Bcl-2 protein in heart tissues.
Most importantly, all parameters induced by the injection of doxorubicin alterations were effectively attenuated by the administration of the purified standardized extract (1.5% withanolides; manufactured by Idea Sphere Inc., American Fork, UT, USA) of Withania somnifera (300 mg/kg).
Based on the evidence, researchers said, "Thus, Withania may play a role in the protection against cardiotoxicity and thus might be a useful adjuvant therapy where doxorubicin is the cancer-treating drug".
Taken altogether, Ashwagandha may be considered supplements for the prevention and treatment of Cardiotoxicity induced by medications, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats by Hamza A1, Amin A, Daoud S. (PubMed)
Wednesday, September 2, 2020
Herbal Ashwagandha Protects the Heart Against Damage in Post Myocardial Injury
The circulatory system consists of the heart, blood vessels, and blood with the function to transport of nutrients, oxygen, and hormones to cells throughout the body and removal of metabolic wastes (carbon dioxide, nitrogenous wastes).
Cardiovascular disease is a class of chronic conditions associated with the heart and blood vessels.
According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression, and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
The World Heart Foundation, in the investigation of CVD, suggested that CVD risk factors can be classified by
* Non-Modified risk factors such as age, ethnic background,....... and family history. The risk that can not be controlled
* Modified risk factors such as smoking, high blood cholesterol, and pressure, diabetes physical inactivity,.... and overweight. These types of risks can be controlled through a change in lifestyle and diet.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the promotion of cardio-functioning, researchers examined the efficacy of Withania somnifera (Ws) to limit myocardial injury after ischemia and reperfusion compared to that of Vit E,
The study included Wistar rats (150-200 g) that were divided into six groups and received orally saline (sham, control group), Ws-50/kg (Ws control and treated group) and Vit E-100 mg/kg (Vit E control and treated group) respectively for 1 month.
According to the results of the experiment of Vit E and Ws treated groups that were anesthetized subjected to 45 min occlusion of the LAD coronary artery followed by 60 min reperfusion on the 31st day,
* Postischemic reperfusion rats showed significant cardiac necrosis, depression of left ventricular functions (MAP, LVEDP, (+) and (-)LVdP/dt) and a significant fall in GSH (p < 0.01), SOD, CAT (p < 0.05).
* Postischemic reperfusion rats also demonstrated a fail in LDH and increased cardio stress markers and levels of MDA, compared to the sham group.
* In comparison tested, Ws and Vit E favorably modulated most of the hemodynamic, biochemical and histopathological parameters though no significant restoration in GSH, mean arterial pressure VAP.
* More importantly, chronic administration of Ws on markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) compared to Vit E that does not stimulate the synthesis of endogenous antioxidants compared to sham.
Based on the evidence, researchers said, "Ws significantly reduced myocardial injury and emphasize the beneficial action of Ws as a cardioprotective agent".
Taken altogether, Ashwagandha may be considered supplements for the treatment of myocardial injury, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment by Gupta SK1, Mohanty I, Talwar KK, Dinda A, Joshi S, Bansal P, Saxena A, Arya DS. (PubMed)
Cardiovascular disease is a class of chronic conditions associated with the heart and blood vessels.
According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.
Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.
Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.
According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.
Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.
The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.
In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression, and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.
The World Heart Foundation, in the investigation of CVD, suggested that CVD risk factors can be classified by
* Non-Modified risk factors such as age, ethnic background,....... and family history. The risk that can not be controlled
* Modified risk factors such as smoking, high blood cholesterol, and pressure, diabetes physical inactivity,.... and overweight. These types of risks can be controlled through a change in lifestyle and diet.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
In the urgency to discover a natural ingredient for the promotion of cardio-functioning, researchers examined the efficacy of Withania somnifera (Ws) to limit myocardial injury after ischemia and reperfusion compared to that of Vit E,
The study included Wistar rats (150-200 g) that were divided into six groups and received orally saline (sham, control group), Ws-50/kg (Ws control and treated group) and Vit E-100 mg/kg (Vit E control and treated group) respectively for 1 month.
According to the results of the experiment of Vit E and Ws treated groups that were anesthetized subjected to 45 min occlusion of the LAD coronary artery followed by 60 min reperfusion on the 31st day,
* Postischemic reperfusion rats showed significant cardiac necrosis, depression of left ventricular functions (MAP, LVEDP, (+) and (-)LVdP/dt) and a significant fall in GSH (p < 0.01), SOD, CAT (p < 0.05).
* Postischemic reperfusion rats also demonstrated a fail in LDH and increased cardio stress markers and levels of MDA, compared to the sham group.
* In comparison tested, Ws and Vit E favorably modulated most of the hemodynamic, biochemical and histopathological parameters though no significant restoration in GSH, mean arterial pressure VAP.
* More importantly, chronic administration of Ws on markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) compared to Vit E that does not stimulate the synthesis of endogenous antioxidants compared to sham.
Based on the evidence, researchers said, "Ws significantly reduced myocardial injury and emphasize the beneficial action of Ws as a cardioprotective agent".
Taken altogether, Ashwagandha may be considered supplements for the treatment of myocardial injury, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
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Holistic System In Existence That Will Show You How-To
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment by Gupta SK1, Mohanty I, Talwar KK, Dinda A, Joshi S, Bansal P, Saxena A, Arya DS. (PubMed)
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