Amyloid beta (Aβ or Abeta) is the main component of the amyloid plaques that cause the gradual death of neurons, leading to the onset of Alzheimer's disease.
Alzheimer's disease is a common form of dementia or neurodegenerative disease found in the elderly.
Alzheimer's disease is a type of dementia correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.
According to the statistics, the disease is most prevalent in the elderly. Approximately 5.7 million Americans of all ages are living with Alzheimer's. 15.9 million family caregivers provide an estimated 18.2 billion hours and $230 billion to people with dementia worldwide.
Alzheimer's disease is caused by a combination of genetic, lifestyle and environmental factors that affect the neurons of the brain over time. However, less than 10% of patients with AD are associated with a genetic preposition. Patients with such mutated genes on chromosomes 21, 14, and 1are virtually guaranteed to develop the disease.
More precisely, Alzheimer's disease is caused by the gradual loss of neuron functioning that usually starts with the early symptom of the difficulty of remembering recent events and worsens over time.
Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia.
Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of mental disorders, researchers examined the effect of cranberry supplementation on β-amyloid aggregation.
According to tested analysis, the cranberry protected the neurons by mediating Aβ toxicity alleviation required heat shock transcription factor (HSF)-1 rather than DAF-16 and SKN-1associated with cellular stress.
In other words, cranberry supplementation reduced Aβ toxicity induced brain cell stress by reducing the transactivity of HSF-1 in an IIS-dependent manner.
More precisely, HSF-1 plays a pivotal role in maintaining proteostasis, a process that regulates proteins within the cell in order to maintain the neuron cellular health involved in oxidative stress.
Based on the findings, researchers aid, "(cranberry) elucidated the mechanism whereby cranberry attenuated Aβ toxicity in C elegans and stressed the significance of proteostasis in the prevention of age-related diseases from a practical point of view.".
Taken altogether, cranberry may be considered a remedy for the treatment of AD, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 in Caenorhabditis elegans Model of Alzheimer’s Disease by
Hong Guo, Min Cao, Sige Zou, 4 Boping Ye, and Yuqing Dong. (PMC)
Sunday, September 13, 2020
Saturday, September 12, 2020
Chaste Tree Berry for Treatment of High Levels Testosterone Induced Male Sexual Libido, Acne and Prostate Disease
A recent study conducted by a renowned institute suggested that Vitex agnus castus (Vac.) may have the potential in decreased overproduction of testosterone on male reproductive physiology.
Testosterone is a male steroid hormone played an important role in male reproductive organs and building bone and muscle mass as well as stimulating sexual desire in both sexes.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
In the study of hydroalcoholic Vac. extract (extraction by percolation technique) with the following doses: 65, 165, 265, 365 and 465 mg kg-', bromocriptine as a dopamine receptor agonist (5, 10, 20 mg kg(-1)) and haloperidol as a dopamine receptor antagonist (1, 1.5, 2, 2.5, 3 mg kg(-1)) injection male mice treated with chaste tree berry extract or combination of the extract showed a significant decrease of levels of testosterone in compared to other treatment groups.
Dr. Nasri S, the lead author said, ". LH and testosterone were measured by Radio Immuno Assay (RIA). LH and testosterone showed a significant decrease in the bromocriptine group and haloperidol increased these hormones. Vac. extract decreased significantly the LH and testosterone levels. The coadministration of Vac. extract and bromocriptine decreased LH and testosterone".
The study also found that Vitex agnus castus extract influences the neurotransmitters such as dopamine in regulated LH and testosterone secretion.
In confirming to the efficacy of chaste tree berry in reduced testosterone production, Vitex agnus castus L. (Vit.) fruit extract with 1650 mg/kg tested on male mice model with the doses (65, 165, 265, 365, 465 mg/kg) injected intraperitoneally for 30 days in 5 groups of animals, all tested mice showed a decreased testosterone levels in dose depending manner.
The researchers also insisted that through the Radio Immuno Assay (RIA), Vit. the fruit extract has an anti-androgenic effect and probably acts through the Hypothalamic-Pituitary-Gonadal (HPG) axis and the side effects only appear after a long time of their usage.
Dr Jillian Stansbury, not the author of the studies said, " (due to the effects of chaste tree berry in reduced LH levels and testosterone levels ) that Vitex may improve symptoms of high testosterone levels in men, including excessive libido, acne, and prostatic disease."
The reduced levels of testosterone of herbal medicine may be beneficial for patients with high levels of testosterone-induced of sexual libido, acne, and abnormal prostate expression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The effects of Vitex agnus castus extract and its interaction with dopaminergic system on LH and testosterone in male mice by Nasri S1, Oryan S, Rohani AH, Amin GR.(PubMed)
(2) The Effects of Vitex agnus castus L. Extract on Gonadotrophines and Testosterone in Male Mice(Researchgate)
(3) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury
Testosterone is a male steroid hormone played an important role in male reproductive organs and building bone and muscle mass as well as stimulating sexual desire in both sexes.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
In the study of hydroalcoholic Vac. extract (extraction by percolation technique) with the following doses: 65, 165, 265, 365 and 465 mg kg-', bromocriptine as a dopamine receptor agonist (5, 10, 20 mg kg(-1)) and haloperidol as a dopamine receptor antagonist (1, 1.5, 2, 2.5, 3 mg kg(-1)) injection male mice treated with chaste tree berry extract or combination of the extract showed a significant decrease of levels of testosterone in compared to other treatment groups.
Dr. Nasri S, the lead author said, ". LH and testosterone were measured by Radio Immuno Assay (RIA). LH and testosterone showed a significant decrease in the bromocriptine group and haloperidol increased these hormones. Vac. extract decreased significantly the LH and testosterone levels. The coadministration of Vac. extract and bromocriptine decreased LH and testosterone".
The study also found that Vitex agnus castus extract influences the neurotransmitters such as dopamine in regulated LH and testosterone secretion.
In confirming to the efficacy of chaste tree berry in reduced testosterone production, Vitex agnus castus L. (Vit.) fruit extract with 1650 mg/kg tested on male mice model with the doses (65, 165, 265, 365, 465 mg/kg) injected intraperitoneally for 30 days in 5 groups of animals, all tested mice showed a decreased testosterone levels in dose depending manner.
The researchers also insisted that through the Radio Immuno Assay (RIA), Vit. the fruit extract has an anti-androgenic effect and probably acts through the Hypothalamic-Pituitary-Gonadal (HPG) axis and the side effects only appear after a long time of their usage.
Dr Jillian Stansbury, not the author of the studies said, " (due to the effects of chaste tree berry in reduced LH levels and testosterone levels ) that Vitex may improve symptoms of high testosterone levels in men, including excessive libido, acne, and prostatic disease."
The reduced levels of testosterone of herbal medicine may be beneficial for patients with high levels of testosterone-induced of sexual libido, acne, and abnormal prostate expression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The effects of Vitex agnus castus extract and its interaction with dopaminergic system on LH and testosterone in male mice by Nasri S1, Oryan S, Rohani AH, Amin GR.(PubMed)
(2) The Effects of Vitex agnus castus L. Extract on Gonadotrophines and Testosterone in Male Mice(Researchgate)
(3) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury
Friday, September 11, 2020
Herbal Chaste Tree Berry, a Valuable Chemotherapeutic Agent for Treatment of Cancers
Chaste tree berry is found to exhibit a significant anti-cancer activity, a recent study by renowned study advised.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Cancer is a class of diseases characterized by cells growing and multiplying disordered and uncontrollable way in our bodies. In the late stage, the cancer cell may travel away from the originated site
to infect other tissues and organs.
According to the Tianjin Institute for Biomedicinal Research, in the evaluated the apoptosis-inducing effect of chaste tree berry, using observation under a light microscope, flow cytometric analysis, and agarose gel electrophoresis, vitexicarpin, a flavonoid found in chaste tree berry significantly inhibited proliferation of human cancer cells lines A2780(human ovarian carcinoma), HCT-15(human, colon, colorectal adenocarcinoma), HT-1080(fibrosarcoma cell line) and K562(Human chronic myeloid leukemia cells), depending to the concentration.
Dr. Wang HY the lead researcher in the study said, "Vitexicarpin induces apoptosis.... via mitochondria(in regulated cell metabolism)-controlled apoptotic pathway".
In support of the above analysis, the crude extract prepared with ethanol from dried ripened Vitex agnus-castus fruits exerted strong cytotoxic effects against cancer cell lines of human uterine cervical canal fibroblast (HCF), human embryo fibroblast (HE-21), ovarian cancer (MCF-7), cervical carcinoma (SKG-3a), breast carcinoma (SKOV-3), gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), and small cell lung carcinoma (Lu-134-A-H) cells.
The inhibition of the extract is attributed to the effect on cell death through apoptosis and increased intracellular oxidation in the tumor cells.
Other researchers suggested that the cytotoxic effects. of Chaste tree berry may be involved in various aspects, including the JNK (apoptosis) pathway. as indicated in the new native lignan VB6 study.
Taking together, there is no doubt, that chaste tree berry may be considered as a valuable chemotherapeutic agent for the treatment of various types of cancer, depending to further evaluation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway].[Article in Chinese] by Wang HY1, Cai B, Cui CB, Zhang DY, Yang BF.(PubMed)
(2) Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth by Ohyama K1, Akaike T, Hirobe C, Yamakawa T.(PubMed)
(3) Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway by Zhou J1, Hu H, Long J, Wan F, Li L, Zhang S, Shi YE, Chen Y.(PubMed)
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Cancer is a class of diseases characterized by cells growing and multiplying disordered and uncontrollable way in our bodies. In the late stage, the cancer cell may travel away from the originated site
to infect other tissues and organs.
According to the Tianjin Institute for Biomedicinal Research, in the evaluated the apoptosis-inducing effect of chaste tree berry, using observation under a light microscope, flow cytometric analysis, and agarose gel electrophoresis, vitexicarpin, a flavonoid found in chaste tree berry significantly inhibited proliferation of human cancer cells lines A2780(human ovarian carcinoma), HCT-15(human, colon, colorectal adenocarcinoma), HT-1080(fibrosarcoma cell line) and K562(Human chronic myeloid leukemia cells), depending to the concentration.
Dr. Wang HY the lead researcher in the study said, "Vitexicarpin induces apoptosis.... via mitochondria(in regulated cell metabolism)-controlled apoptotic pathway".
In support of the above analysis, the crude extract prepared with ethanol from dried ripened Vitex agnus-castus fruits exerted strong cytotoxic effects against cancer cell lines of human uterine cervical canal fibroblast (HCF), human embryo fibroblast (HE-21), ovarian cancer (MCF-7), cervical carcinoma (SKG-3a), breast carcinoma (SKOV-3), gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), and small cell lung carcinoma (Lu-134-A-H) cells.
The inhibition of the extract is attributed to the effect on cell death through apoptosis and increased intracellular oxidation in the tumor cells.
Other researchers suggested that the cytotoxic effects. of Chaste tree berry may be involved in various aspects, including the JNK (apoptosis) pathway. as indicated in the new native lignan VB6 study.
Taking together, there is no doubt, that chaste tree berry may be considered as a valuable chemotherapeutic agent for the treatment of various types of cancer, depending to further evaluation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) [Vitexicarpin, a flavonoid from Vitex trifolia L., induces apoptosis in K562 cells via mitochondria-controlled apoptotic pathway].[Article in Chinese] by Wang HY1, Cai B, Cui CB, Zhang DY, Yang BF.(PubMed)
(2) Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth by Ohyama K1, Akaike T, Hirobe C, Yamakawa T.(PubMed)
(3) Vitexin 6, a novel lignan, induces autophagy and apoptosis by activating the Jun N-terminal kinase pathway by Zhou J1, Hu H, Long J, Wan F, Li L, Zhang S, Shi YE, Chen Y.(PubMed)
Thursday, September 10, 2020
Bromelain Improves the Symptoms and Quality of Life in Patients with Cystic Fibrosis
Cystic fibrosis (CF) is a genetic preposition that leads to diseases mostly in the lungs in children and young adults.
Most cases of CF has been found to cause persistent infection in the lungs, leading to the destruction of lung tissues and reduced lung function, depending on the severity of the condition.
Most common complication of CF is difficulty digesting fats, proteins and nutrient absorption, progressive lung damage caused by ongoing infections and chronic low-grade inflammation and CF-related diabetes.
According to statistics provided by the Canadian Cystic Fibrosis Foundation, approximately 1 in every 3,600 children born in Canada has CF.
In age perspective,
* 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.
* More than 47% of all Canadians with CF are over the age of 18 years.
* As of 2002, the median age of survival of Canadians with CF is 37 years of age.
The most common symptoms of CF are persistent cough with productive thick mucous, wheezing and shortness of breath, frequent chest infections, weight loss or failure to gain weight, infertility in men and decreased fertility in women.
Conventionally, as of today, there is no cure for CF. Medications are focusing on reducing symptoms and improving quality of life, including
* Antibiotics for the treatment of lung infections.
* Anti-inflammatory medications to protect the lung airways.
* Medication to reduce cough up the mucus
* Inhaled medications to keep your airways open by relaxing the muscles around your bronchial tubes
* Medication to help the digestive tract in absorbing nutrients
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of cystic fibrosis, researchers compared with identical capsules half-filled with mini-tablets of a new high lipase preparation in a randomized double-blind crossover study in children with cystic fibrosis.
All children who participated in the study received his/her usual number of capsules and the same dose of lipase during each period of the study.
According to the results from the 18 children who completed the study, the pancreatic enzyme applied in the high lipase preparation showed fewer gastrointestinal symptoms compared to the low lipase group.
Compared to the baseline, the pancreatic enzyme group showed a significant improvement in fat absorption and reduction in fecal fat output.
Fecal energy loss was also improved in the treatment group.
Based on the findings, researchers at the St James's Hospital wrote, " (The) half filled capsules of the new high lipase preparation are more effective than the standard preparation and it is likely that filled capsules would allow patients to use fewer than half the number of pancreatic enzyme capsules".
Taken altogether, bromelain may be considered supplements for the prevention and treatment of symptoms of cystic fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements by Croft NM1, Marshall TG, Ferguson A. (PubMed)
(2) A double blind lipase for lipase comparison of a high lipase and standard pancreatic enzyme preparation in cystic fibrosis by Bowler IM1, Wolfe SP, Owens HM, Sheldon TA, Littlewood JM, Walters MP. (PubMed)
Most cases of CF has been found to cause persistent infection in the lungs, leading to the destruction of lung tissues and reduced lung function, depending on the severity of the condition.
Most common complication of CF is difficulty digesting fats, proteins and nutrient absorption, progressive lung damage caused by ongoing infections and chronic low-grade inflammation and CF-related diabetes.
According to statistics provided by the Canadian Cystic Fibrosis Foundation, approximately 1 in every 3,600 children born in Canada has CF.
In age perspective,
* 60% of patients are diagnosed in the first year of life, and 90% by 10 years of age.
* More than 47% of all Canadians with CF are over the age of 18 years.
* As of 2002, the median age of survival of Canadians with CF is 37 years of age.
The most common symptoms of CF are persistent cough with productive thick mucous, wheezing and shortness of breath, frequent chest infections, weight loss or failure to gain weight, infertility in men and decreased fertility in women.
Conventionally, as of today, there is no cure for CF. Medications are focusing on reducing symptoms and improving quality of life, including
* Antibiotics for the treatment of lung infections.
* Anti-inflammatory medications to protect the lung airways.
* Medication to reduce cough up the mucus
* Inhaled medications to keep your airways open by relaxing the muscles around your bronchial tubes
* Medication to help the digestive tract in absorbing nutrients
Bromelain, a proteolytic enzyme found in pineapples (Ananas comosus) has been used in traditional medicine as an inflammatory agent and to treat pains, strains, and muscle aches and pains and ease back pain and chronic joint pain, skin diseases, etc.
On finding a natural compound for the treatment of cystic fibrosis, researchers compared with identical capsules half-filled with mini-tablets of a new high lipase preparation in a randomized double-blind crossover study in children with cystic fibrosis.
All children who participated in the study received his/her usual number of capsules and the same dose of lipase during each period of the study.
According to the results from the 18 children who completed the study, the pancreatic enzyme applied in the high lipase preparation showed fewer gastrointestinal symptoms compared to the low lipase group.
Compared to the baseline, the pancreatic enzyme group showed a significant improvement in fat absorption and reduction in fecal fat output.
Fecal energy loss was also improved in the treatment group.
Based on the findings, researchers at the St James's Hospital wrote, " (The) half filled capsules of the new high lipase preparation are more effective than the standard preparation and it is likely that filled capsules would allow patients to use fewer than half the number of pancreatic enzyme capsules".
Taken altogether, bromelain may be considered supplements for the prevention and treatment of symptoms of cystic fibrosis, pending to the confirmation of the larger sample size and multicenter human study.
Intake of bromelain in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Gut inflammation in children with cystic fibrosis on high-dose enzyme supplements by Croft NM1, Marshall TG, Ferguson A. (PubMed)
(2) A double blind lipase for lipase comparison of a high lipase and standard pancreatic enzyme preparation in cystic fibrosis by Bowler IM1, Wolfe SP, Owens HM, Sheldon TA, Littlewood JM, Walters MP. (PubMed)
Wednesday, September 9, 2020
Herbal Coltsfoot Improves Asthmatic Symptoms
Respiratory disease is medical conditions that affect the breathing organ and tissues including Inflammatory lung disease, obstructive lung diseases, restrictive lung diseases, respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves, and muscles breathing,...
The most common symptom of respiratory disease is shortness of breath.
The lungs formed part of the respiratory symptoms, sare a pair of spongy, air-filled organs located on either side of the chest (thorax). The organ plays a critical role in inhaling oxygens to the body and exhaling carbon dioxide from the body.
Asthma is a medical and chronic condition characterized by the long-term inflammation of the airways of the lungs.
Most common symptoms of asthma are episodes of wheezing, coughing, chest tightness, and shortness of breath, and reversible airflow obstruction, and bronchospasm.
Asthma attack in most cases is triggered by exposure to various irritants and substances that trigger allergies (allergens). However, genetic preposition and family history are also found in patients with asthma.
Asthma not only interferes with daily activities and also can lead to a life-threatening asthma attack. Treatment of asthma is to reduce the frequent episode and severity of the attacks.
According to the statistics provided by the Centers for Disease Control and Prevention (CDC), in the US, 1 in 13 people have asthma. In other words, over 26 million Americans have asthma and half of that is children.
Believe it or not, African-Americans in the U.S. die from asthma at a higher rate than people of other races or ethnicities.
Dr. Laurent Guilleminault, in the examing environmental effect in the risk asthma, said, "The rates of asthma and allergy (Type 1 hypersensitivity disorders) have been increasing worldwide for the last few decades. Various theories have been proposed to account for this alarming trend. One of these is the impact of environmental toxicants".
And, "depletion of glutathione levels (with oral supplementation of N-acetylcysteine), and enhancement of glutathione transferase function (using sulforaphane) might be therapeutic options for countering type 1 hypersensitivity disorders caused by environmental chemicals".
In other words, environmental toxins cause reduced levels of antioxidant in the body are associated with the risk of asthma onset
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of respiratory disease, researchers examined the effect of invigorating Kidney (Viscum coloratum 15g, Psoralea corylifolia 15g, Eucommia ulmoides 15g, Lycium chinense 9g, Tussilago farfara 15g, Artemisia capillaris 9g, and Pogostemon cablin 9g as daily dosage) on asthma by measuring maximal expiratory flow-volume curve (MEFV) in the convalescent stage.
In a total of 66 cases of asthmatics were examined, researchers found that before treatment by the invigorating Kidney decoction, the results of FEV, PEF, V75, V50, V25 in 35 cases or 53.03% of the total demonstrated a significantly negative effect compared with healthy persons.
In other words, in the convalescent stage, convalescent stage, over half of the asthmatics showed obstruction of airways and chiefly of small airways.
According to the tested analysis after treatment of the decoction only exerted effects on different parameters associated with the improvement of MEFV to some extent, but also reversed the airway obstruction of asthmatics in the convalescent stage.
Based on the findings, researchers said, "the authors indicated that the prompt treatment for asthmatics in the convalescent stage was conductive early to prevent emphysema and confirmed that the treatment with Chinese herbs of chiefly invigorating Kidney deserved to be propagated.".
Taken altogether, coltsfoot used alone and combined with other herbal medicine may be considered a remedy for the treatment of asthmatics in the convalescent stage, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs].[Article in Chinese] by Fu JX. (PubMed)
(2) Do environmental toxicants contribute to allergy and asthma? by Crinnion WJ. (PubMed)
The most common symptom of respiratory disease is shortness of breath.
The lungs formed part of the respiratory symptoms, sare a pair of spongy, air-filled organs located on either side of the chest (thorax). The organ plays a critical role in inhaling oxygens to the body and exhaling carbon dioxide from the body.
Asthma is a medical and chronic condition characterized by the long-term inflammation of the airways of the lungs.
Most common symptoms of asthma are episodes of wheezing, coughing, chest tightness, and shortness of breath, and reversible airflow obstruction, and bronchospasm.
Asthma attack in most cases is triggered by exposure to various irritants and substances that trigger allergies (allergens). However, genetic preposition and family history are also found in patients with asthma.
Asthma not only interferes with daily activities and also can lead to a life-threatening asthma attack. Treatment of asthma is to reduce the frequent episode and severity of the attacks.
According to the statistics provided by the Centers for Disease Control and Prevention (CDC), in the US, 1 in 13 people have asthma. In other words, over 26 million Americans have asthma and half of that is children.
Believe it or not, African-Americans in the U.S. die from asthma at a higher rate than people of other races or ethnicities.
Dr. Laurent Guilleminault, in the examing environmental effect in the risk asthma, said, "The rates of asthma and allergy (Type 1 hypersensitivity disorders) have been increasing worldwide for the last few decades. Various theories have been proposed to account for this alarming trend. One of these is the impact of environmental toxicants".
And, "depletion of glutathione levels (with oral supplementation of N-acetylcysteine), and enhancement of glutathione transferase function (using sulforaphane) might be therapeutic options for countering type 1 hypersensitivity disorders caused by environmental chemicals".
In other words, environmental toxins cause reduced levels of antioxidant in the body are associated with the risk of asthma onset
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of respiratory disease, researchers examined the effect of invigorating Kidney (Viscum coloratum 15g, Psoralea corylifolia 15g, Eucommia ulmoides 15g, Lycium chinense 9g, Tussilago farfara 15g, Artemisia capillaris 9g, and Pogostemon cablin 9g as daily dosage) on asthma by measuring maximal expiratory flow-volume curve (MEFV) in the convalescent stage.
In a total of 66 cases of asthmatics were examined, researchers found that before treatment by the invigorating Kidney decoction, the results of FEV, PEF, V75, V50, V25 in 35 cases or 53.03% of the total demonstrated a significantly negative effect compared with healthy persons.
In other words, in the convalescent stage, convalescent stage, over half of the asthmatics showed obstruction of airways and chiefly of small airways.
According to the tested analysis after treatment of the decoction only exerted effects on different parameters associated with the improvement of MEFV to some extent, but also reversed the airway obstruction of asthmatics in the convalescent stage.
Based on the findings, researchers said, "the authors indicated that the prompt treatment for asthmatics in the convalescent stage was conductive early to prevent emphysema and confirmed that the treatment with Chinese herbs of chiefly invigorating Kidney deserved to be propagated.".
Taken altogether, coltsfoot used alone and combined with other herbal medicine may be considered a remedy for the treatment of asthmatics in the convalescent stage, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [Measurement of MEFV in 66 cases of asthma in the convalescent stage and after treatment with Chinese herbs].[Article in Chinese] by Fu JX. (PubMed)
(2) Do environmental toxicants contribute to allergy and asthma? by Crinnion WJ. (PubMed)
Tuesday, September 8, 2020
Fennel, the Best Functional Food to Normalizes Your Blood Cholesterol Quickly With No Side Effects
Scientists may have found a natural whole food with the potential to treat hyperlipidemia without inducing any side effects, some studies suggested.
Cholesterol, the natural ingredient produced in the liver plays an important role in stimulating the production of vitamin D, steroid hormones, and bile acids and maintaining healthy cell membranes.
Hyperlipidemia is a condition characterized by abnormally elevated levels of cholesterol in the plasma of the blood.
The causes of hyperlipidemia are unknown. However, an unhealthy diet with a lot of unsaturated fat and trans fat is associated with the early onset of the disease. Foods such as cheese egg yolks fried and processed foods and red meat have found to increase blood cholesterol, long-term intake of such foods in great amount have been found to increase the risk of hyperlipidemia, epidemiological studies found.
The Beni-Suef University, in the study to determine the development of obesity in response to a high-fat diet (HFD) an Egyptian Herbal mixture formulation (HMF), including fennel, showed, "feeding HFD diet significantly increased final body weight, triglycerides (TG), total cholesterol, & LDL concentration compared with controls, while significantly decreasing HD".
Hyperlipidemia is a lifelong condition that is treatable.
Dr. Robert B. Kelly at the Fairview Hospital/Cleveland Clinic Family Medicine Residency Program in the article "The most beneficial changes result from reducing intake of saturated and trans fats; increasing intake of polyunsaturated and monounsaturated fats; fortifying foods with plant stanols or sterols; isocalorically adding tree nuts to the diet; consuming one or two alcoholic drinks per day; and adopting a Portfolio, Mediterranean, low-carbohydrate, or low-fat diet. Smaller but still beneficial effects result from reducing intake of dietary cholesterol, increasing intake of soluble fiber and soy protein, and eating fatty marine fish or taking marine-derived omega-3 fatty acid supplements".
Therefore by changing the diet pattern and engaging regular physical exercise are the fundamental
options that not only can prevent the onset of the condition, particularly in people who are at a higher risk of hyperlipidemia and also treat high blood cholesterol in patients who already have the condition.
Fennel (Foeniculum vulgare) is a plant species of a genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The plant has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle, and relieve PMS.
In the study to examine the effect of the aqueous extract of fennel in the reduced risk of hyperlipidemia, researchers conducted an experiment in Triton WR-1339 induced hyperlipidemia in mice.
Mice treated with the extract at different doses displays a significant reduction of cholesterol, triglycerides, LDL-cholesterol, and apolipoprotein-B decreased by 40%, 23%, 61%, and 61%, respectively.
Further analysis, the application also increased the levels of HDL-cholesterol and apolipoprotein A1 by 85% and 58%, respectively
According to the Mashhad University of Medical Sciences which also conducted a study to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles, in sixty eligible postmenopausal women, randomly assigned into the fennel and placebo groups.
Measurement of total blood cholesterol, cholesterol fractions, and triglycerides was tested at the baseline, and after a three-month follow-up.
At the end of 3 months, blood profiled withdrawn from the women suggested
* There are no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol(LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups.
* Fennel treated group demonstrates a significant borderline improvement for HDL-C and triglyceride, compared to the placebo group.
Additional differentiation of the process of the double-blind, randomized, and placebo-controlled trial, researchers suggested that longer durations, higher doses, and larger sample sizes are recommended to validate the results.
These results indicated that the intake of foods for the treatment of conditions or diseases must be on a long-term basis. The times of 3 months may be too short for foods to exert their potential effects.
Taken all together, fennel may be considered a functional food for the prevention and treatment of hyperlipidemia. Intake of fennel should be increased gradually for the food to reach its antihyperlipidemic stage, a longer duration may be needed. In other words, please be patient.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial by Afiat M1, Amini E2, Ghazanfarpour M3, Nouri B4, Mousavi MS5, Babakhanian M6, Rakhshandeh H(PubMed)
(3) Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats by Amin KA1, Nagy M(PubMed)
Cholesterol, the natural ingredient produced in the liver plays an important role in stimulating the production of vitamin D, steroid hormones, and bile acids and maintaining healthy cell membranes.
Hyperlipidemia is a condition characterized by abnormally elevated levels of cholesterol in the plasma of the blood.
The causes of hyperlipidemia are unknown. However, an unhealthy diet with a lot of unsaturated fat and trans fat is associated with the early onset of the disease. Foods such as cheese egg yolks fried and processed foods and red meat have found to increase blood cholesterol, long-term intake of such foods in great amount have been found to increase the risk of hyperlipidemia, epidemiological studies found.
The Beni-Suef University, in the study to determine the development of obesity in response to a high-fat diet (HFD) an Egyptian Herbal mixture formulation (HMF), including fennel, showed, "feeding HFD diet significantly increased final body weight, triglycerides (TG), total cholesterol, & LDL concentration compared with controls, while significantly decreasing HD".
Hyperlipidemia is a lifelong condition that is treatable.
Dr. Robert B. Kelly at the Fairview Hospital/Cleveland Clinic Family Medicine Residency Program in the article "The most beneficial changes result from reducing intake of saturated and trans fats; increasing intake of polyunsaturated and monounsaturated fats; fortifying foods with plant stanols or sterols; isocalorically adding tree nuts to the diet; consuming one or two alcoholic drinks per day; and adopting a Portfolio, Mediterranean, low-carbohydrate, or low-fat diet. Smaller but still beneficial effects result from reducing intake of dietary cholesterol, increasing intake of soluble fiber and soy protein, and eating fatty marine fish or taking marine-derived omega-3 fatty acid supplements".
Therefore by changing the diet pattern and engaging regular physical exercise are the fundamental
options that not only can prevent the onset of the condition, particularly in people who are at a higher risk of hyperlipidemia and also treat high blood cholesterol in patients who already have the condition.
Fennel (Foeniculum vulgare) is a plant species of a genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The plant has been used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle, and relieve PMS.
In the study to examine the effect of the aqueous extract of fennel in the reduced risk of hyperlipidemia, researchers conducted an experiment in Triton WR-1339 induced hyperlipidemia in mice.
Mice treated with the extract at different doses displays a significant reduction of cholesterol, triglycerides, LDL-cholesterol, and apolipoprotein-B decreased by 40%, 23%, 61%, and 61%, respectively.
Further analysis, the application also increased the levels of HDL-cholesterol and apolipoprotein A1 by 85% and 58%, respectively
According to the Mashhad University of Medical Sciences which also conducted a study to assess the effects of Fennel (Foeniculum vulgare Mill.) on lipid profiles, in sixty eligible postmenopausal women, randomly assigned into the fennel and placebo groups.
Measurement of total blood cholesterol, cholesterol fractions, and triglycerides was tested at the baseline, and after a three-month follow-up.
At the end of 3 months, blood profiled withdrawn from the women suggested
* There are no significant difference in triglyceride (P = 0.679), total cholesterol (P = 0.103), low-density lipoprotein cholesterol(LDL-C; P = 0.146) and high-density lipoprotein cholesterol (HDL-C; P = 0.266) levels between the two groups.
* Fennel treated group demonstrates a significant borderline improvement for HDL-C and triglyceride, compared to the placebo group.
Additional differentiation of the process of the double-blind, randomized, and placebo-controlled trial, researchers suggested that longer durations, higher doses, and larger sample sizes are recommended to validate the results.
These results indicated that the intake of foods for the treatment of conditions or diseases must be on a long-term basis. The times of 3 months may be too short for foods to exert their potential effects.
Taken all together, fennel may be considered a functional food for the prevention and treatment of hyperlipidemia. Intake of fennel should be increased gradually for the food to reach its antihyperlipidemic stage, a longer duration may be needed. In other words, please be patient.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PMC)
(2) The Effect of Short-term Treatment with Fennel on Lipid Profile in Postmenopausal Women: A Randomized Controlled Trial by Afiat M1, Amini E2, Ghazanfarpour M3, Nouri B4, Mousavi MS5, Babakhanian M6, Rakhshandeh H(PubMed)
(3) Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats by Amin KA1, Nagy M(PubMed)
Monday, September 7, 2020
Herbal Bilberry, The Best Functional Food For Nonalcoholic Fatty Liver Disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is a type of noninflammatory fatty liver disease caused by fat accumulated in the liver other than excessive alcohol consumption.
People who have an accumulation of triglycerides within hepatocytes that exceeds 5% of liver weight are considered to have nonalcoholic fatty liver disease.
According to the statistics, nonalcoholic fatty liver disease (NAFLD) has risen rapidly over the past few decades and become the most common cause of chronic liver disease in the developing world. The disease affects between 17-30% of the population in Western countries and 2-4% worldwide.
Epidemiologically. obesity, type II diabetes, dyslipidemia, and insulin resistance are the well-known primary causes of NAFLD.
The findings strongly suggested that NAFLD is a geographically related disease associated with dietary patterns.
Dr. Alanna McCarthy, the lead scientist in the examination of diet pattern in the risk NAFLD wrote, "Non-alcoholic fatty liver disease (NAFLD) is a serious consequence of high-fat diet intake and currently affects approximately one-third of the world’s entire population".
And, "Recent evidence suggests that patients with NAFLD have a higher incidence of cardiovascular disease compared to the general population. However, little is known about the link between NAFLD and pathological cardiac remodeling leading to heart disease".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find natural prevention and treatment of non-alcoholic fatty liver disease (NAFLD), researchers investigated the effects of anthocyanin supplementation on insulin resistance and liver injury biomarkers in patients.
74 subjects with NAFLD included in the study were divided into 2 groups in this double-blind, randomized study. Patients received either purified anthocyanin (320 mg/d) derived from bilberry and black currant or placebo for 12 weeks.
During the experiment, the anthocyanin group exhibited significantly decreased in plasma alanine aminotransferase, cytokeratin-18 M30 fragment, and myeloperoxidase, the biomarkers associated with NAFLD, compared to controls.
Compared to the baseline, the anthocyanin group significantly decreased in fasting blood glucose and homeostasis model assessment for insulin resistance, however, these differences were not significant relative to placebo controls.
Not surprisingly, anthocyanin supplementation significantly decreased the 2-hour loading glucose level compared to control, according to the oral glucose tolerance test.
Based on the findings, researchers said, "A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients".
Furthermore, according to the results from the study of ApoE(∗)3Leiden mice fed a Western-type cholesterol-containing diet without (HC) or with 0.1% (w/w) Mirtoselect (HCM), an anthocyanin-rich bilberry extract for 20weeks on diet-induced NASH, Mirtoselect treatment group showed an attenuated HC-induced hepatic steatosis and reduced hepatic cholesteryl ester content.
Furthermore, injection of Mirtoselect also exerted local anti-inflammatory effects in the liver by reduced inflammatory cell clusters and neutrophil infiltration in HCM.
In other words, HCM protected the liver against HC diet significantly induced hepatic expression of pro-inflammatory and pro-fibrotic genes associated with the onset of NAFLD.
Dr. Morrison MC, the lead scientist, after taking other factors into account wrote, "Mirtoselect attenuates the development of NASH, reducing hepatic lipid accumulation, inflammation, and fibrosis, possibly mediated by local anti-inflammatory effects associated with reduced accumulation and crystallization of intrahepatic free cholesterol".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the treatment of nonalcoholic fatty liver disease, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease by Zhang PW1, Chen FX, Li D, Ling WH, Guo HH. (PubMed)
(2) Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice by Morrison MC1, Liang W2, Mulder P2, Verschuren L2, Pieterman E2, Toet K2, Heeringa P3, Wielinga PY2, Kooistra T2, Kleemann R. (PubMed)
(3) High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease and Cardiac Physiology in Mice by
Alanna McCarthy and Stephen Luckey. (Faseb Journal)
People who have an accumulation of triglycerides within hepatocytes that exceeds 5% of liver weight are considered to have nonalcoholic fatty liver disease.
According to the statistics, nonalcoholic fatty liver disease (NAFLD) has risen rapidly over the past few decades and become the most common cause of chronic liver disease in the developing world. The disease affects between 17-30% of the population in Western countries and 2-4% worldwide.
Epidemiologically. obesity, type II diabetes, dyslipidemia, and insulin resistance are the well-known primary causes of NAFLD.
The findings strongly suggested that NAFLD is a geographically related disease associated with dietary patterns.
Dr. Alanna McCarthy, the lead scientist in the examination of diet pattern in the risk NAFLD wrote, "Non-alcoholic fatty liver disease (NAFLD) is a serious consequence of high-fat diet intake and currently affects approximately one-third of the world’s entire population".
And, "Recent evidence suggests that patients with NAFLD have a higher incidence of cardiovascular disease compared to the general population. However, little is known about the link between NAFLD and pathological cardiac remodeling leading to heart disease".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find natural prevention and treatment of non-alcoholic fatty liver disease (NAFLD), researchers investigated the effects of anthocyanin supplementation on insulin resistance and liver injury biomarkers in patients.
74 subjects with NAFLD included in the study were divided into 2 groups in this double-blind, randomized study. Patients received either purified anthocyanin (320 mg/d) derived from bilberry and black currant or placebo for 12 weeks.
During the experiment, the anthocyanin group exhibited significantly decreased in plasma alanine aminotransferase, cytokeratin-18 M30 fragment, and myeloperoxidase, the biomarkers associated with NAFLD, compared to controls.
Compared to the baseline, the anthocyanin group significantly decreased in fasting blood glucose and homeostasis model assessment for insulin resistance, however, these differences were not significant relative to placebo controls.
Not surprisingly, anthocyanin supplementation significantly decreased the 2-hour loading glucose level compared to control, according to the oral glucose tolerance test.
Based on the findings, researchers said, "A 12-week supplement of purified anthocyanin improved insulin resistance, indicators of liver injury, and clinical evolution in NAFLD patients".
Furthermore, according to the results from the study of ApoE(∗)3Leiden mice fed a Western-type cholesterol-containing diet without (HC) or with 0.1% (w/w) Mirtoselect (HCM), an anthocyanin-rich bilberry extract for 20weeks on diet-induced NASH, Mirtoselect treatment group showed an attenuated HC-induced hepatic steatosis and reduced hepatic cholesteryl ester content.
Furthermore, injection of Mirtoselect also exerted local anti-inflammatory effects in the liver by reduced inflammatory cell clusters and neutrophil infiltration in HCM.
In other words, HCM protected the liver against HC diet significantly induced hepatic expression of pro-inflammatory and pro-fibrotic genes associated with the onset of NAFLD.
Dr. Morrison MC, the lead scientist, after taking other factors into account wrote, "Mirtoselect attenuates the development of NASH, reducing hepatic lipid accumulation, inflammation, and fibrosis, possibly mediated by local anti-inflammatory effects associated with reduced accumulation and crystallization of intrahepatic free cholesterol".
Taken altogether, bilberry processed abundantly bioactive compound anthocyanin may be considered a functioning remedy for the treatment of nonalcoholic fatty liver disease, pending to the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease by Zhang PW1, Chen FX, Li D, Ling WH, Guo HH. (PubMed)
(2) Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice by Morrison MC1, Liang W2, Mulder P2, Verschuren L2, Pieterman E2, Toet K2, Heeringa P3, Wielinga PY2, Kooistra T2, Kleemann R. (PubMed)
(3) High-Fat-Diet Induced Non-Alcoholic Fatty Liver Disease and Cardiac Physiology in Mice by
Alanna McCarthy and Stephen Luckey. (Faseb Journal)
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