Tuesday, March 1, 2016

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Bronchitis Treatments In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Lower respiratory tract infection


The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

                             Bronchitis

Bronchitis is defined as a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma(7). Most cases of Bronchitis are as a result of recurrent injure to the airways caused by inhaled irritants and cigarette smoking(6). 

                          Treatments

 In conventional medicine perspective
The aim of the treatment is to relive the symptoms, such as cough, pain, breathing, etc.
A. Acute bronchitis
Cough is the most common symptom bringing patients to the primary care physician’s office, and acute bronchitis is usually the diagnosis in these patients. Getting more rest, taking over-the-counter pamedicine to relieve the symptoms, drinking fluids, breathing in warm, moist air. According to the study by Hartford Hospital, Hartford, acute bronchitis should be differentiated from other common diagnoses, such as pneumonia and asthma, because these conditions may need specific therapies not indicated for bronchitis. Symptoms of bronchitis typically last about three weeks. The typical therapies for managing acute bronchitis symptoms have been shown to be ineffective, and the U.S. Food and Drug Administration recommends against using cough and cold preparations in children younger than six years. The supplement pelargonium may help reduce symptom severity in adults. As patient expectations for antibiotics and therapies for symptom management differ from evidence-based recommendations, effective communication strategies are necessary to provide the safest therapies available while maintaining patient satisfaction(49).
B. Chronic bronchitis
The syndrome of chronic obstructive pulmonary disease (COPD) consists of chronic bronchitis (CB), bronchiectasis, emphysema, and reversible airway disease that combine uniquely in an individual patient. Older patients are at risk for COPD and its components–emphysema, CB, and bronchiectasis. Bacterial and viral infections play a role in acute exacerbations of COPD (AECOPD) and in acute exacerbations of CB (AECB) without features of COPD(50).
Beside over counter medince to reduce symptoms of the disease, prescriptions medication may include
1. Antibiotics
Antibiotics are medication used to fight against the bacetrial invasion. Gemifloxacin is a fluoroquinolone antibiotic with broad spectrum of antibacterial activity. In the study to to evaluate the comparative effectiveness and safety of gemifloxacin for the treatment of patients with community-acquired pneumonia (CAP) or acute exacerbation of chronic bronchitis (AECB), found that gemifloxacin 320 mg oral daily is equivalent or superior to other approved antibiotics in effectiveness and safety for CAP and AECB. The development of rash represents potential limitation of gemifloxacin(51). But other suggested that older patients are at risk for resistant bacterial organisms during their episodes of AECOPD and AECB. Organisms include the more-common bacteria implicated in AECOPD/AECB such as Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae. Using a risk-stratification approach for elderly patients, first-line antibiotics (e.g., amoxicillin, ampicillin, pivampicillin, trimethoprim/sulfamethoxazole, and doxycycline), with a more-limited spectrum of antibacterial coverage, are used in patients who are likely to have a low probability of resistant organisms during AECOPD/AECB. Second-line antibiotics (e.g., amoxicillin/clavulanic acid, second- or third-generation cephalosporins, and respiratory fluoroquinolones) with a broader spectrum of coverage are reserved for patients with significant risk factors for resistant organisms and those who have failed initial antibiotic treatment(52).
Side effects are ot limit to rash, diarrhea, abdominal pain, nausea/vomiting, drug fever, hypersensitivity (allergic) reactions, etc.
2. Blockade of the Epidermal growth factors receptors (EGFR) therapy
In the study to examine the expression patterns of EGF and their receptors (EGFR1 and c-erbB2) in the bronchial mucosa from the biopsy specimens harvested from smoking and non-smoking CB patients, compared with their expression in normal controls, indicated that blockade of the EGFR pathway can be an alternative successful therapy(53).
3. Surgery
Chronic bronchitis is a common but variable phenomenon in COPD. It has numerous clinical consequences, including an accelerated decline in lung function, greater risk of the development of airflow obstruction in smokers, a predisposition to lower respiratory tract infection, higher exacerbation frequency, and worse overall mortality(54). Lung reduction surgery can be potential helpful in removing the damage lung area. According to the study by University of Pennsylvania, lung-volume-reduction surgery increases the chance of improved exercise capacity but does not confer a survival advantage over medical therapy. It does yield a survival advantage for patients with both predominantly upper-lobe emphysema and low base-line exercise capacity(55).
4. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) http://www.who.int/whr/2004/en/
(6) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130746/
(7) http://www.lung.org/lung-disease/bronchitis-chronic/understanding-chronic-bronchitis.html
(49) http://www.ncbi.nlm.nih.gov/pubmed/21121518
(50) http://www.ncbi.nlm.nih.gov/pubmed/20398122
(51) http://www.ncbi.nlm.nih.gov/pubmed/22490497
(52) http://www.ncbi.nlm.nih.gov/pubmed/20398122
(53) http://www.ncbi.nlm.nih.gov/pubmed/23303019
(54) http://www.ncbi.nlm.nih.gov/pubmed/23204254
(55) http://www.ncbi.nlm.nih.gov/pubmed/12759479

Monday, February 29, 2016

The Best Smoothie of Sweet Potato, Tomato and Orange Juice for Prevention and Treatment of Granular cell tumor (GCT) of the breast, a benign breast disease

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and Treatment of  Granular cell tumor (GCT) of the breast, a benign breast disease
Yield: 2 serving (about 8 ounce each)
1/8 cup cooked sweet potato
1/4 cup tomato
1 4/5 cups orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Granular cell tumor (GCT) of the breast is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine to other organs in the body. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Granular cell tumor (GCT) of the breast, a benign breast disease is an abnormal growth of breast tissue, affecting 5% to 6% of all GCTs.  Although Granular cell tumor (GCT) of the breast is not a precursor of breast cancer, women with Granular cell tumor (GCT) of the breast are at increased risk of developed invasive breast cancer(1).

Women with benign breast disease(BBD) are found to have lower antioxidant status, probably to compensate for this elevated free radical production(3)

According to the, dietary supplement "Karinat" containing beta-carotene 2.5 mg, alpha-tocopherol 5 mg, ascorbic acid 30 mg and garlic powder 150 mg per one tablet in a total of 66 patients twice a day during 6 months exhibited anti benign breast disease up to 75.8% in comparison to placebo(2).

According to the Chinese University of Hong Kong, Intakes of vitamin E and individual carotenoids may associate to reduce risk proliferative BBD(4), particular in carotenoids intake in BBD of adolescent girls(5).

Dr. Ramaswamy G and Dr. Krishnamoorthy L. said, "Serum ascorbate levels were significantly lower in patients with benign diseases of the breast and cervix than in controls"(6).

The effectiveness of Sweet Potato(Vitamin E), Tomato(Vitamin A) and Orange Juice(Ascorbic Acid or Vitamin C )  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Granular cell tumor (GCT) of the breast, a benign disease of the breast with little or no adverse effects.

Women who are at increased risk of Granular cell tumor (GCT) of the breast may drink at least one serving daily and women with Granular cell tumor (GCT) of the breast may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


References
(1) Benign breast disease and the risk of breast cancer in the next 15 years by Socolov D, Anghelache I, Ilea C, Socolov R, Carauleanu A.(PubMed)
(2) [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease].
[Article in Russian] by Bespalov VG, Barash NIu, Ivanova OA, Krzhivitskiĭ PI, Semiglazov VF, Aleksandrov VA, Sobenin NA, Orekhov AN.(PubMed)
(3) Lipid peroxidation and antioxidant status in blood and tissue of malignant breast tumor and benign breast disease by Gönenç A1, Erten D, Aslan S, Akinci M, Simşek B, Torun M.(PubMed)
(4) Intakes of fat and micronutrients between ages 13 and 18 years and the incidence of proliferative benign breast disease. by Su X1, Boeke CE, Collins LC, Baer HJ, Willett WC, Schnitt SJ, Connolly JL, Rosner B, Colditz GA, Tamimi RM.(PubMed)
(5) Adolescent carotenoid intake and benign breast disease by Boeke CE1, Tamimi RM2, Berkey CS3, Colditz GA4, Eliassen AH2, Malspeis S5, Willett WC6, Frazier AL7.(PubMed)
(6) Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix. by Ramaswamy G1, Krishnamoorthy L.(PubMed)


Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Bronchitis Preventions – The Antioxidants

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Lower respiratory tract infection


The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

                             Bronchitis

Bronchitis is defined as a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma(7). Most cases of Bronchitis are as a result of recurrent injure to the airways caused by inhaled irritants and cigarette smoking(6). 

                                             Prevention

Antioxidants to prevent bronchitis
1. Antioxidant vitamins C, E and coenzyme Q10
In the study to to evaluate the effects of antioxidant vitamins (vitamin C and E), Coenzyme Q10 (CoQ10) and dexamethasone (Dxm) in experimental rat models with pulmonary contusion (PC), showed that Administration of CoQ10 resulted in a significant increase in PaO2 values compared with the group I (p = 0.004). Levels of plasma MDA in group II were significantly higher than those in the group I (p = 0.01). Early administration of vitamin C, CoQ10, and Dxm significantly decreased the levels of MDA (p = 0.01). Lung contusion due to blunt trauma significantly decreased SOD activities in rat lung tissue compared with group I (p = 0.01). SOD levels were significantly elevated in animals treated with CoQ10, Vitamin E, or Dxm compared with group II (p = 0.01)(46).
2. Vitamin D
In the cohort to investigate the association of maternal vitamin D and maternal asthma and infant respiratory infection severity of 70% white, 19% African American, and 21% had asthma, found that
overall, the median maternal vitamin D level was 20 ng/mL (interquartile range, 14-28). Among white women, a 14 ng/mL increase in vitamin D was associated with a decreased odds of asthma (adjusted odds ratio, 0.54; 95% confidence interval, 0.33-0.86). Maternal vitamin D was not associated with infant bronchiolitis score(47).
3. Curcumin
Curcumin derived from the rhizome of turmeric has been used for decades and it exhibits anti-inflammatory, anti-carcinogenic, immunomodulatory properties by downregulation of various inflammatory mediators,. according to the study by Panjab University(48)
4. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.who.int/whr/2004/en/
(6) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130746/
(7) http://www.lung.org/lung-disease/bronchitis-chronic/understanding-chronic-bronchitis.html
(46) http://www.ncbi.nlm.nih.gov/pubmed/23013526
(47) http://www.ncbi.nlm.nih.gov/pubmed/21658670
(48) http://www.ncbi.nlm.nih.gov/pubmed/16025962

****244 Breast hematoma The Smoothie of Orange, Spinach and Grape Juice for Prevention and Treatment of Breast Hematoma

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Breast hematoma
1  cup of organic orange
1/2 spinach
1 cup organic grape juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of  Breast hematoma has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(such as Ginger, Alfalfa Sprout  and Orange) for reduced risk and treatment of Breast hematoma.

Breast hematoma is a collection of blood due to bleeding within the breast. According to the Penn State Milton S. Hershey Medical Center, "The probability of development of a non-clinically significant hematoma was 21.6% for patients taking antithrombotics and 13.0% for those not taking antithrombotics"(1).

Vitamin K, found abundantly in spinach has exerted its coagulation effects in reduced risk of (subdural) hematoma, in a randomized trials identified from the Cochrane Central Register of Controlled Trials(2).
The Fuwai Hospital joint study also suggested, the favorite uninterrupted vitamin K antagonists (VKAs), in comparison to anticoagulation in catheter ablation (CA) of atrial fibrillation (AF) in occurrence of stroke or transient ischemic attacks and major bleeding in test subjects(3).
Dr. Levi M said, "Bleeding is the most important adverse effect of antithrombotic treatment and may be a major cause of morbidity, longstanding debilitation, and even mortality....... can be neutralized by the administration of vitamin K or prothrombin complex concentrates"(4).

Vitamin C, a water soluble vitamin found in orange may also benefit women with breast hematoma by preventing the breaking off  capillaries, the small vessels in the breast inducing bleeding(5).
According to the University Clinic Muenster, Vitamin C was shown to be cerebroprotective in several animal models of stroke, through the expression and transport activity of SVCT2, :key proteins for vitamin C uptake. in brain capillary endothelial cells after transhwaient ischemia in mice(6).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape may also reduced risk of complications caused by severe hemorrhagic injury, including the Lung(8), intestines(9), cystitis(10),.....through both pro and anti-inflammatory pathways(7).

The effectiveness of Orange, Spinach and Grape Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Breast hematoma with little or no adverse effects.

Women who are at increased risk of Breast hematoma due to family history, aging,.....may drink at least one serving daily and women with  Breast hematoma may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

References
(1) Hematoma formation during breast core needle biopsy in women taking antithrombotic therapy by Chetlen AL1, Kasales C, Mack J, Schetter S, Zhu J.(PubMed)
(2) Vitamin K antagonists and risk of subdural hematoma: meta-analysis of randomized clinical trials by Connolly BJ1, Pearce LA1, Hart RG2.(PubMed)
(3) Meta-Analysis of Efficacy and Safety of New Oral Anticoagulants Compared With UninterruptedVitamin K Antagonists in Patients Undergoing Catheter Ablation for Atrial Fibrillation. by Wu S1, Yang YM2, Zhu J1, Wan HB1, Wang J1, Zhang H1, Shao XH1.(PubMed)
(4) Emergency Reversal Strategies for Anticoagulation and Platelet Disorders by Levi M1.(PubMed)
(5) High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats by Kremer T1, Harenberg P, Hernekamp F, Riedel K, Gebhardt MM, Germann G, Heitmann C, Walther A.(PubMed)
(6) Sodium-dependent vitamin C transporter 2 (SVCT2) expression and activity in brain capillaryendothelial cells after transient ischemia in mice by Gess B1, Sevimli S, Strecker JK, Young P, Schäbitz WR.(PubMed)
(7) Alteration of cytokine profile following hemorrhagic shock by Lu S1, Aguilar A1, Subramani K1, Poulose N1, Ayub A1, Raju R2.(PubMed)
(8) Dihydro-Resveratrol Ameliorates Lung Injury in Rats with Cerulein-Induced Acute Pancreatitis by Lin ZS1,2, Ku CF1, Guan YF1, Xiao HT1, Shi XK1, Wang HQ2, Bian ZX1, Tsang SW1,3, Zhang HJ1.(PubMed)
(9) Effects of resveratrol on methotrexate-induced intestinal injury by Yulug E, Turedi S, Alver A, Turedi S, Kahraman C.(PubMed)
(10) Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna by Keles I1, Bozkurt MF, Cemek M, Karalar M, Hazini A, Alpdagtas S, Keles H, Yildiz T, Ceylan C, Buyukokuroglu ME.(PubMed)

The Best Smoothie of Coffee, Wolfberry and Honey for Reduced Risk and Treatment of Liver Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published
 on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for reduced risk and treatment of  Liver cancer
Yield: 2 servings (about 8 ounces each)
1/2  cup dried wolfberry (you can easily buy them in any Chinese grocery store)
1/4 cup honey
1 1/2 cup coffee

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately.

Liver cancer is a condition of out of controlled growth of hepatocellular cells in the liver. Since the organ is a soft tissue with less nerve, most liver cancer patient are diagnosed in the later stage of the cancer. According to the statistic, liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide. Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.
Back by well known institutions, according to the recent studies, coffee(1), wolfberry(4) and artichoke(7) may be next potential therapeutic target for producing a curable medication for reduced risk and treatment of liver cancer.
Coffee drink made from roasted coffee beans and considered as one most popular beverage in Western countries may consist the property in ameliorate risk of liver cancer. According to the joint study lead by the Harvard School of Public Health, intake of coffee regularly inversely associated to reduced HCC risk was partly accounted for by biomarkers of inflammation and hepatocellular injury(1).
In the Liver Cancer Pooling Project, a consortium of U.S.-based cohort studies, data from 1,212,893 individuals, higher coffee consumption was associated with lower risk of HCC, among women than men (HR>3 cups/day vs. non-drinker)(2).
Furthermore, according to a prospective study in Japan, risk of liver cancer in almost never drinkers in this population was 547.2 cases per 100,000 people over 10 years, in comparison of 214.6 cases per 100 000 people with drinking coffee on a daily basis(3).

Wolfberry is the common name for the fruit of two very closely related species, the genus of Lycium, belong to family Solanaceae, native to native to southeastern Europe and Asia. According to the General Hospital of Ningxia Medical University, Lycium barbarum berries, improved general wellbeing and immune functions and exhibited antitumor activities against various types of cancer cells through induction of apoptosis and cell cycle arrest(4).
On human hepatoma cells, Lycium barbarum polysaccharide (LBP) extracted, displayed anti proliferation of SMMC-7721 cells in a concentration and time dependent manner(5) and QGY7703 cells in increased intracellular calcium in apoptotic system(7).
Dr. Cui B and colleagues at the Sun Yat-sen University said," LCP exhibited remarkable protective effects against diethylnitrosamine (DEN)-induced oxidative hepatic injury in liver cancer rats(6).

Honey, the rich golden liquid, is the miraculous product made by bees using nectar from flowers. It is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people. According to State University of Campinas-UNICAM, honey treatment affect the tumor and host caused by oxidative stress through different mechanisms(8), such as decreasing cell proliferation and increasing apoptosis in tumour tissue(9).The study of bee honey and Nigella sativa on hepatocellular carcinoma cells BY THE Ain Shams University, showed a positive effects of honey in reducing the viability of HepG2 cells, improving their antioxidant status and inducing their apoptotic death(10).

The discovery of combined ingredients of wolfberry(4), coffee(1) and honey(8) may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of liver cancer.
People who are at increased risk of liver cancer due to family history, gene mutation, obesity.....should drink at least one serving daily and people with liver cancer should drink no more than 4 servings daily, depending to digestive toleration.
Change of life style and diet pattern are also recommended.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(1) The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: data from the European Prospective Investigation into Cancer and Nutrition by Aleksandrova K1, Bamia C2, Drogan D3, Lagiou P4, Trichopoulou A2, Jenab M5, Fedirko V6, Romieu I5, Bueno-de-Mesquita HB7, Pischon T8, Tsilidis K9,Overvad K10, Tjønneland A11, Bouton-Ruault MC12, Dossus L12, Racine A12, Kaaks R13, Kühn T13, Tsironis C14, Papatesta EM14, Saitakis G14, Palli D15,Panico S16, Grioni S17, Tumino R18, Vineis P19, Peeters PH20, Weiderpass E21, Lukic M22, Braaten T22, Quirós JR23, Luján-Barroso L24, Sánchez MJ25,Chilarque MD26, Ardanas E27, Dorronsoro M28, Nilsson LM29, Sund M30, Wallström P31, Ohlsson B32, Bradbury KE33, Khaw KT34, Wareham N35, Stepien M5,Duarte-Salles T5, Assi N5, Murphy N36, Gunter MJ36, Riboli E36, Boeing H3, Trichopoulos D37.(PubMed)
(2) Coffee Consumption and Risk of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma by Sex: TheLiver Cancer Pooling Project by Petrick JL1, Freedman ND2, Graubard BI2, Sahasrabuddhe VV2, Lai GY3, Alavanja MC2, Beane-Freeman LE2, Boggs DA4, Buring JE5, Chan AT6, Chong DQ7,Fuchs CS8, Gapstur SM9, Gaziano JM10, Giovannucci EL11, Hollenbeck AR12, King LY6, Koshiol J2, Lee IM5, Linet MS2, Palmer JR4, Poynter JN13, Purdue MP14, Robien K15, Schairer C2, Sesso HD5, Sigurdson AJ2, Zeleniuch-Jacquotte A16, Wactawski-Wende J17, Campbell PT9, McGlynn KA2.(PubMed)
(3) Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: a prospective study in Japan by Inoue M1, Yoshimi I, Sobue T, Tsugane S; JPHC Study Group.(PubMed)
(4) An evidence-based update on the pharmacological activities and possible molecular targets ofLycium barbarum polysaccharides by Cheng J1, Zhou ZW2, Sheng HP3, He LJ4, Fan XW5, He ZX6, Sun T7, Zhang X8, Zhao RJ9, Gu L10, Cao C2, Zhou SF11(PubMed)
(5) Characterization of Lycium barbarum polysaccharide and its effect on human hepatoma cells by Zhang M1, Tang X, Wang F, Zhang Q, Zhang Z.(PubMed)
(6) Antitumour activity of Lycium chinensis polysaccharides in liver cancer rats by Cui B1, Chen Y, Liu S, Wang J, Li S, Wang Q, Li S, Chen M, Lin X.(PubMed)
(7) Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis by Zhang M1, Chen H, Huang J, Li Z, Zhu C, Zhang S.(PubMed)
(8) Oral Administration of Aloe vera (L.) Burm. f. (Xanthorrhoeaceae) and Honey Improves the Host Body Composition and Modulates Proteolysis Through Reduction of Tumor Progression and Oxidative Stress in Rats by Tomasin R1, de Andrade RS1, Gomes-Marcondes MC1.(PubMed)
(9) Oral administration of Aloe vera and honey reduces Walker tumour growth by decreasing cell proliferation and increasing apoptosis in tumour tissue by Tomasin R1, Gomes-Marcondes MC.(PubMed)
(10) Antineoplastic effects of bee honey and Nigella sativa on hepatocellular carcinoma cells BY Hassan MI1, Mabrouk GM, Shehata HH, Aboelhussein MM.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Bronchitis Preventions – The Phytochemicals

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                            Respiratory Disease 

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                     Lower respiratory tract infection


The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

                             Bronchitis

Bronchitis is defined as a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma(7). Most cases of Bronchitis are as a result of recurrent injure to the airways caused by inhaled irritants and cigarette smoking(6). 

                                             Prevention

Phytochemicals to prevent bronchitis
1. Quercetin
Mucus hypersecretion is a feature of many chronic airway diseases induced by cigarette smoke (CS), and evidence suggests that the antioxidant and anti-inflammatory flavonoid quercetin may protect against CS-induced respiratory pathology. According to the study by State Key Laboratory of Biotherapy and Department of Respiratory Medicine, West China Hospital, Sichuan University, quercetin attenuates CS-induced mucin protein synthesis in rat lung, possibly by inhibiting oxidative stress and inflammation via a mechanism involving NF-κB pathway activation and EGFR phosphorylation. These findings suggest that quercetin has a potential for treating chronic airway diseases(42).
2. Catechin
Catechin found abundantly in Actinidia callosa var. ephippioides extract also had good effects in the antioxidant and anti-inflammatory activities. Catechin might be an important bioactive compound in the stem of ACE. The above experimental data indicated that the stem of ACE is a potent antioxidant medicinal plant, and such efficacy may be mainly attributed to its polyphenolic compounds(43).
3. Eupafolin
Eupafolin found abundantly in Kalanchoe gracilis (L.) DC stem also had good pharmacological activity in the antioxidant, anti-inflammation and antiproliferative. Eupafolin might be an important bioactive compound in the stem of K. gracilis. The above experimental data indicated that the stem of K. gracilis is a potent antioxidant medicinal plant, and such efficacy may be mainly attributed to its polyphenolic compounds(44).
4. Puerarin
Puerarin is a major isoflavonoid derived from the Chinese medical herb Radix puerariae (kudzu root), In the study to investigate the myocardial protective effect of puerarin injection (PI) in children with severe pneumonia, conducted by Hospital Affiliated to Weifang Medical College, indicated that
change of serum myocardial zymographic parameters was indirectly proportional to the severity of childrens condition. The reduction of myocardialcontrastive function was demonstrated by the change of cardiac blood flow parameters in Ultrasound Doppler examination (P < 0.01). Both PI and FDP had the effect in protecting myocardium and improving heart function, showing insignificant difference between their efficacy (P > 0.05), but PI had less stimulation to vessels and without any obvious adverse reaction(45).
5. Etc.
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Sources
(1) http://www.who.int/whr/2004/en/
(6) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC130746/
(7) http://www.lung.org/lung-disease/bronchitis-chronic/understanding-chronic-bronchitis.html
(42) http://www.ncbi.nlm.nih.gov/pubmed/22465384
(43) http://www.ncbi.nlm.nih.gov/pubmed/22928834
(44) http://www.ncbi.nlm.nih.gov/pubmed/22083996
(45) http://www.ncbi.nlm.nih.gov/pubmed/16025962

Sunday, February 28, 2016

The Delicious Smoothie of Tomato, Sweet Potato and Orange Juice for Prevention and Treatment of Fibroadenomas

Kyle J. Norton(Scholar, master of nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Fibroadenomas
Yield: 2 servings (about 8 ounces each)
3/4 cup tomato
3/4 cup sweet potato
1 cup organic orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of fibroadenomas has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources( Tomato, Sweet Potato and Orange Juice) for reduced risk and treatment of fibroadenomas. According to the Dr. Bespalov VG and research team, dietary supplement "Karinat" containing beta-carotene 2.5 mg, alpha-tocopherol 5 mg, ascorbic acid 30 mg may be effective for prevention and treatment of patients with benign breast disease(1) including Fibroadenomas

Fibroadenomas are benign breast tumors composed of fibrous and glandular tissue which occur mostly in women 30 years old or younger. According to statistic, approximately 500,000-700,000 fibroadenomas are removed each year in US alone. The benign breast tumors are also called breast mice or a breast mouse due to their high mobility in the breast. They are general painless and may become tenderness or swelling just before the menstrual cycle. Women with multiple fibroadenomas may indicate a slightly increased risk of breast cancer.

Tomato, a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America,  containing high amount of beta-carotene, may be used for prevention and treatment of
Fibroadenomas(1). According to the Medical Academy of Bialystok, in Carotenoid pigments isolated, beta carotene, is associated to lower risk of benign changes of fibroadenoma(2).

α-Tocopherol is a type of tocopherol or vitamin E found abundantly in sweet potato may also be associated to risk of fibroadenomas(3). Sweet potato is a large, starchy, sweet tasting tuberous roots vegetable, genus Ipomoea, belongings to the family Convolvulaceae.
According to the Bandar Baru Bangi, higher adipose tissue concentrations of tocotrienols in benign patients provide support for the idea that tocotrienols may provide protection against breast cancer(4).
Ar. London SJ and research team at the said, " We observed no significant associations between serum levels of these micronutrients and risk of proliferative BBD or breast cancer. The risk of breast cancer was decreased among women in the highest quintile of intake of vitamin E from food sources only"(5).

Vitamin C, found abundantly in orange, is a water soluble vitamin with a chemical structure formula of C6H6O6 and cannot be stored in the body for more than 24 hours. We are required to take it regularly. According to Dr. Ramaswamy G and Dr. Krishnamoorthy L., serum ascorbate levels were significantly lower in patients with benign diseases of the breast and cervix(6).
The Medical College, in the review of data from January 1992-January 1998 of 1404 patients attended the "Breast Clinic" of R.N.T. Medical College M.B. Hospital, Udaipur, in comparison of patients had breast cancer (B.C.) and benign breast cancer (B.B.D.), depleted levels of ascorbic acid were found in most patients(7).

The combination of smoothie with ingredients Tomato, Sweet Potato and Orange Juice may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of fibroadenomas without induced adverse effects

Women who are at increased risk of fibroadenomas due to family history,... should drink at least one cup daily. Women with fibroadenomas, should drink no more than 4 serving daily depending to the digestive toleration.

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References
(1) [Study of an antioxidant dietary supplement "Karinat" in patients with benign breast disease].[Article in Russian] by Bespalov VG, Barash NIu, Ivanova OA, Krzhivitskiĭ PI, Semiglazov VF, Aleksandrov VA, Sobenin NA, Orekhov AN.(PubMed)
(2) Preliminary identification of carotenoids in malignant and benign neoplasms of the breast and surrounding fatty tissue by Czeczuga-Semeniuk E1, Wołczyński S, Markiewicz W.(PubMed)
(3) [Serum values of vitamins A, E, C and carotenoids in healthy adult subjects and those with breast neoplasia].[Article in Italian] by Audisio M, Mastroiacovo P, Martinoli L, Fidanza A, Cappelli L, Pasquali Lasagni R, Tirelli C, Jacobelli G.(PubMed)
(4) Tocotrienol levels in adipose tissue of benign and malignant breast lumps in patients in Malaysia by Nesaretnam K1, Gomez PA, Selvaduray KR, Razak GA.(PubMed)
(5) Carotenoids, retinol, and vitamin E and risk of proliferative benign breast disease and breast cancer. by London SJ1, Stein EA, Henderson IC, Stampfer MJ, Wood WC, Remine S, Dmochowski JR, Robert NJ, Willett WC.(PubMed)
(6) Serum carotene, vitamin A, and vitamin C levels in breast cancer and cancer of the uterine cervix by Ramaswamy G1, Krishnamoorthy L.(PubMed)
(7) Breast cancer in developing population: A nutrition caveat by Mehta G1, Kothari S, Singh PP.(PubMed)