Tuesday, August 2, 2016

Herbal therapy: Popular Herbal Raspberry Leaf

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


 Herbal Raspberry Leaf


Raspberries are perennial, the edible fruit of a multitude of plant species in the genus Rubus belonging to the family Rosaceae, originated from Europe. Raspberry Leaf has been used in traditional medicine as pain reliever and to aid fertility, promote production of breastmilk, stop excess bleeding after birth, treat morning sickness, enhance muscle relaxation, regulate menses, etc.

Health Benefits
1. Induced labor
In the investigation of the direct effects of various commercially available preparations of red raspberry leaf (RRL) on the in vitro contractility of uteri collected from diethylstilbestrol (DES)-treated nonpregnant (NP) and late pregnant rats, found that in pregnant animals red raspberry leaf tea had variable effects on preexisting oxytocin-induced contractions, sometimes augmenting oxytocin's effect and sometimes causing augmentation followed by inhibition. We conclude that the biological activity of RRL varies depending on the herbal preparation used and pregnancy status, according to "The effects of commercial preparations of red raspberry leaf on the contractility of the rat's uterus in vitro" by Jing Zheng, Pistilli MJ, Holloway AC, Crankshaw DJ.(1)

2. Microbial oral diseases
In the identification of the positive or negative action on microbial oral disease such as caries and gingivitis, of seven food/beverages (red chicory, mushroom,raspberry, green and black tea, cranberry juice, dark beer), found that water soluble components occurring in raspberry, chicory, and mushroom extracts (which in microbiological assays revealed the highest potential action against oral pathogens), according to "Plant and fungal food components with potential activity on the development of microbial oral diseases" by Daglia M, Papetti A, Mascherpa D, Grisoli P, Giusto G, Lingström P, Pratten J, Signoretto C, Spratt DA, Wilson M, Zaura E, Gazzani G.(2)

3. Relaxant activity
In the evaluation of extracts of dried raspberry leaves prepared with different solvents, (n-hexane, ethyl acetate, chloroform and methanol) were tested in vitro for relaxant activity on transmurally stimulated guinea-pig ileum found that The fractions eluted with chloroform (CHCl(3)) lacked relaxant activity. Samples eluted with CHCl(3)/MeOH (95:5) had moderate relaxant activity, while a second distinctive peak of activity eluted with a more polar solvent mixture (CHCl(3)/MeOH 50:50) provided strong dose dependent responses. Evidence was obtained that there are at least two components of raspberry leaf extract which exhibit relaxant activity in an in vitro gastrointestinal preparation, according to "Relaxant activity of raspberry (Rubus idaeus) leaf extract in guinea-pig ileum in vitro" by Rojas-Vera J, Patel AV, Dacke CG.(3)

4. Antibacterial activity
In the assessment of the antimicrobial properties of raspberry juice cordial,raspberry juice, raspberry leaf extract found that Raspberry cordial and juice were found to significantly reduce the growth of several species of bacteria, including Salmonella, Shigella and E. coli, but demonstrated no antifungal activity. No antimicrobial activity was detected in the leaf extract or tea, according to "Antibacterial activity of raspberry cordial in vitro" by Ryan T, Wilkinson JM, Cavanagh HM.(4)

5. Laryngeal Carcinoma and Colon Adenocarcinoma
In the determination of the polyphenolic profile and antioxidative properties of redraspberry leaf extract and its Cytotoxic effect, antioxidative/prooxidative effect found that The results obtained confirmed the biological activity of red raspberryleaf polyphenols and showed that this traditional plant can supplement the daily intake of valuable natural antioxidants, which exhibit beneficial health effects, according to "The Bioactive Potential of Red Raspberry (Rubus idaeus L.)Leaves in Exhibiting Cytotoxic and Cytoprotective Activity on Human Laryngeal Carcinoma and Colon Adenocarcinoma" by Durgo K, Bel Ak-Cvitanovi A, Stan I A, Franeki J, Komes DE.(5)

6. Pancreatic cancer
In the investigation of the efficacy of bioactive phytochemicals in inhibiting radiotherapy (RT)-induced NF-κB activity, signaling, and NF-κB-dependent regulation of cell death.
found that CUR, NLE, and RSE may serve as effective "deliverables" to potentiate RT in PC cure and further throw light that these phytochemicals-induced cell killing may involve selective regulation of RT-induced NF-κB, according to "Impact of curcumin, raspberry extract, and neem leaf extract on rel protein-regulated cell death/radiosensitization in pancreatic cancer cells" by Veeraraghavan J, Natarajan M, Lagisetty P, Awasthi V, Herman TS, Aravindan N.(6)

7. Radical scavenging activity
In the study of the extract of Raspberry (Rubus idaeus) leaves and their antioxidant activity (AA) found that All extracts were active, with radical scavenging capacity at the used concentrations from 20.5 to 82.5% in DPPH(.) reaction system and from 8.0 to 42.7% in ABTS(.)(+) reaction. The total amount of phenolic compounds in the leaves varied from 4.8 to 12.0 mg of gallic acid equivalents (GAE) in 1 g of plant extract. Quercetin glucuronide, quercetin-3-O-glucoside and rutin were identified in the extracts, according to "Radical scavenging activity and composition of raspberry (Rubus idaeus) leaves from different locations in Lithuania" by Venskutonis PR, Dvaranauskaite A, Labokas J.(7)

8. Antileukaemic activity
In the determination the antileukaemic activity of extracts obtained from selected berry plant leaves (Fragaria x ananassa Duch. cv Elsanta, raspberry Rubus ideus L. cv Polana and blueberry Vaccinium corymbosum L. cv Bluecrop) against promyelocytic HL60 cell line, found that strawberry and raspberry extracts exhibited the high cytotoxic activity against sensitive leukaemia HL60 cell line as well as its MDR sublines. The values of resistance factor (RF) found for these extracts were very low lying in the range 0.32/2.0, according to "In vitro antileukaemic activity of extracts from berry plant leaves against sensitive and multidrug resistant HL60 cells" by Skupień K, Oszmiański J, Kostrzewa-Nowak D, Tarasiuk J.(8)

9. Antioxidant activity
In the investigation of Fruits and leaves from different cultivars of thornless blackberry (Rubus sp.), red raspberry (Rubus idaeus L.), black raspberry (Rubus occidentalis L.), and strawberry (Fragaria x ananassa D.) plants and theirsl antioxidant capacity
found that a linear correlation between total phenolic content and ORAC activity for fruits and leaves. Jewel black raspberry and blackberries may be the richest source for antioxidants. On the basis of the dry weight of fruit, strawberries had the highest ORAC activity followed by black raspberries (cv. Jewel), blackberries, and red raspberries, according to "Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage" by Wang SY, Lin HS.(9)

10. Etc.

Side effects
1. Raspberry may cause gastrointestinal discomfort, including abdominal cramping and diarrhea.
2. The herb may cause allergic effect to certain people
3. Do not use the herb in children or if you are pregnant without approval from the related field specialist as Raspberry leaf use during pregnancy was associated with increased gestation length and accelerated reproductive development in the F1 offspring(a)
4. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/19276407
(1) http://www.ncbi.nlm.nih.gov/pubmed/20220111
(2) http://www.ncbi.nlm.nih.gov/pubmed/22013381
(3) http://www.ncbi.nlm.nih.gov/pubmed/12410549
(4) http://www.ncbi.nlm.nih.gov/pubmed/11798288
(5) http://www.ncbi.nlm.nih.gov/pubmed/22082102
(6) http://www.ncbi.nlm.nih.gov/pubmed/21697760
(7) http://www.ncbi.nlm.nih.gov/pubmed/17215088
(8) http://www.ncbi.nlm.nih.gov/pubmed/16039042
(9) http://www.ncbi.nlm.nih.gov/pubmed/10691606

Phytochemicals in Foods - The Effects of Chlorogenic acid

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                      Chlorogenic acid




Chlorogenic acid is a phytochemical in the class of Hydroxycinnamic acids, found abundantly in strawberries, pineapple, coffee, sunflower, blueberries, etc.

Health Benefits
1. Anti oxidative effects
In the investigation of the impact of consumption of a coffee containing high levels of chlorogenic acids on the oxidation of proteins, DNA and membrane lipids; additionally, other redox biomarkers were monitored in an intervention trial, found that the oxidation of DNA, lipids and proteins associated with the incidence of various diseases and the protection against their oxidative damage may be indicative for beneficial health effects of coffee, according to "Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules" by Hoelzl C, Knasmüller S, Wagner KH, Elbling L, Huber W, Kager N, Ferk F, Ehrlich V, Nersesyan A, Neubauer O, Desmarchelier A, Marin-Kuan M, Delatour T, Verguet C, Bezençon C, Besson A, Grathwohl D, Simic T, Kundi M, Schilter B, Cavin C.(1)

2. Hepatoprotective effects
In the investigation of the potential protective effects of chlorogenic acid (CGA) on acute liver injury caused by lipopolysaccharide (LPS) in mice, found that CGA also decreased the elevated plasma levels of ALT and AST. At the transcriptional level, CGA pretreatment suppressed hepatic mRNA expression of toll-like receptor 4 (TLR4), TNF-alpha and NF-kappaB p65 subunit. In contrast, mRNA level of the transcriptional coactivator PGC-1alpha was restored by CGA. Finally, CGA reduced the phosphorylation of NF-kappaB p65 subunit in the liver, according to "Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice" by Xu Y, Chen J, Yu X, Tao W, Jiang F, Yin Z, Liu C.(2)

3. Anti-obesity
in the investigation of the efficacy of chlorogenic acid on altering body fat in high-fat diet (37% calories from fat) induced-obese mice compared to caffeic acid. Caffeic acid or chlorogenic acid was supplemented with high-fat diet at 0.02% (wt/wt) dose, found that Caffeic acid and chlorogenic acid significantly inhibited fatty acid synthase, 3-hydroxy-3-methylglutaryl CoA reductase and acyl-CoA:cholesterol acyltransferase activities, while they increased fatty acid beta-oxidation activity and peroxisome proliferator-activated receptors alpha expression in the liver compared to the high-fat group, and concluded that caffeic acid andchlorogenic acid improve body weight, lipid metabolism and obesity-related hormones levels in high-fat fed mice. Chlorogenic acid seemed to be more potent for body weight reduction and regulation of lipid metabolism than caffeic acid, according to "Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice" by Cho AS, Jeon SM, Kim MJ, Yeo J, Seo KI, Choi MS, Lee MK.(3)

4. Anti-inflammatory and antinociceptive effects
In the assessment in vivo of the anti-inflammatory and antinociceptive activities of the aerial part and root extracts of Scorzonera acuminata, Scorzonera cana var. alpina, Scorzonera cana var. jacquiniana, Scorzonera cana var. radicosa, Scorzonera cinerea, Scorzonera eriophora, Scorzonera incisa, Scorzonera laciniata ssp. laciniata, Scorzonera parviflora and Scorzonera sublanata and theirs effect against inflammation and to relieve pain, found that Scorzonera cana var. jacquiniana, Scorzonera cinerea, Scorzonera eriophora, Scorzonera incisa and Scorzonera parviflora possess significant anti-inflammatory and antinociceptive activity. It has been suggested that flavonoids and chlorogenic acid are partly responsible for mentioned activities of Scorzonera species, according to "Ethnopharmacological evaluation of some Scorzonera species: In vivo anti-inflammatory and antinociceptive effects" by Küpeli Akkol E, Bahadır Acıkara O, Süntar I, Ergene B, Saltan Çitoğlu G.(4)

5. Antioxidants
In the study of the chemical composition and the antioxidant activity of spent coffee grounds and coffee husks extracts, obtained by supercritical fluid extraction (SFE) with CO(2) and with CO(2) and co-solvent, found that the best antioxidant activity was showed by coffee husk extracts obtained by LPE. The quantification and the identification of the extracts were accomplished using HPLC analysis. The main compounds identified were caffeine and chlorogenic acid for the supercritical extracts from coffee husks, according to "Supercritical fluid extraction from spent coffee grounds and coffee husks: Antioxidant activity and effect of operational variables on extract composition" by Andrade KS, Gonçalvez RT, Maraschin M, Ribeiro-do-Valle RM, Martínez J, Ferreira SR.(5)

6. Antitussive
In the investigation of the orally administrated the water extracts in mice. Ammonia induced mice coughing model was used to evaluate the antitussive activity, found that only flower bud can be used as the antitussive and expectorant herbal drug. The high concentration of chlorogenic acid, 3,5-dicaffeoylquinic acid, rutin in flower buds may be related with the antitussive and expectorant effects of Flos Farfara. To guarantee the clinical effect, rachis should be picked out before use, according to "Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice" by Li ZY, Zhi HJ, Xue SY, Sun HF, Zhang FS, Jia JP, Xing J, Zhang LZ, Qin XM.(6)

7. Rheumatoid Arthritis
In the investigation the antiarthritic activities of this compound in adjuvant induced-arthritis in male Wistar rats, and exploration of the underlying mechanisms of actions in view of immunological responses, found that CGA efficiently suppressed CD80/86 but failed to bring any changes in the CD28 count, whereas ibuprofen (standard drug) resulted in highly significant inhibition of both. We next examined the effect on CD4(+) T cells specific Th1/Th2 cytokines by flow cytometry and observed that CGA suppressed the Th1 cytokines in a highly significant manner but elevated Th2 cytokines with dose dependence. Results of the present investigation suggest that CGA is a potent antiarthritic agent, according to "Differential Effects of Chlorogenic Acid on Various Immunological Parameters Relevant to Rheumatoid Arthritis" by Chauhan PS, Satti NK, Sharma P, Sharma VK, Suri KA, Bani S.(7)

8. Antioxidant and antimicrobial effects
In the investigation of the antioxidant and antimicrobial activities and phenolic components of different solvent (absolute methanol, absolute ethanol, absolute acetone, 80% methanol, 80% ethanol, 80% acetone and deionized water) extracts of leaves, flowers and bark of Gold Mohar [Delonix regia (Bojer ex Hook.) Raf.], found that 80% methanol extract produced from the leaves exhibited significantly (P < 0.05) higher antioxidant activity, with high phenolic contents (3.63 g GAE/100 g DW), total flavonoid contents (1.19 g CE/100 g DW), inhibition of peroxidation (85.54%), DPPH scavenging capacity (IC(50) value 8.89 μg/mL) and reducing power (1.87). Similarly, this 80% methanol leaves extract also showed superior antimicrobial activity. HPLC analysis of the 80% methanol extracts for individual phenolics revealed the presence of gallic, protocatechuic and salicylic acid in leaves; gallic, protocatechuic, salicylic, trans-cinnamic and chlorogenic acid in flowers, and gallic acid in bark as the main (amount > 1.50 mg/100 g DW) phenolic acids, according to "Antioxidant and antimicrobial attributes and phenolics of different solvent extracts from leaves, flowers and bark of Gold Mohar [Delonix regia (Bojer ex Hook.) Raf]" by Shabir G, Anwar F, Sultana B, Khalid ZM, Afzal M, Khan QM, Ashrafuzzaman M.(8)

9. Apoptosis and mutagenicity
In the investigation of whether the PBMCs death induced by cold aqueous extract of Baccharis articulata (Ba-CAE) a sa result of apoptosis, and whether this extract exerts mutagenic effects on mice at 24 and 48h after administration.
found that the extract induced PBMCs death by apoptosis and increased the frequency of micronuclei in bone marrow. The phytochemical study of cold aqueous extract of Baccharis articulata (Ba-CAE) i showed the presence of flavones as luteolin and acacetin, caffeoylquinic acids as chlorogenic acid, and tannins, according to "Apoptosis and mutagenicity induction by a characterized aqueous extract of Baccharis articulata (Lam.) Pers. (Asteraceae) on normal cells" by Cariddi L, Escobar F, Sabini C, Torres C, Reinoso E, Cristofolini A, Comini L, Núñez Montoya S, Sabini L.(9)

10. Colon cancer and liver cancer
In the evaluation for antioxidant activity, total phenolics, chlorogenic acid, anthocyanin content, and in vitro anticancer capacity, found that the relationship between antioxidant activity and EC(50) of colon cancer/liver cancer cell proliferation was significant (R(2) = 0.8144; R(2) = 0.956, respectively). A significant difference in inhibition of cancer cells (P < 0.01) existed between the 3 polyphenols: chlorogenic acid, pelargonidin chloride, and malvidin chloride, suggesting that chlorogenic acid was a critical factor in the antiproliferation of colon cancer and liver cancer cells, according to "Inhibitory effect of antioxidant extracts from various potatoes on the proliferation of human colon and liver cancer cells' by Wang Q, Chen Q, He M, Mir P, Su J, Yang Q.(10)

11. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, 
Eat Yourself Healthy With The Best of the Best Nature Has to Offer


Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20589860
(2) http://www.ncbi.nlm.nih.gov/pubmed/20405164
(3) http://www.ncbi.nlm.nih.gov/pubmed/20064576
(4) http://www.ncbi.nlm.nih.gov/pubmed/22285519
(5) http://www.ncbi.nlm.nih.gov/pubmed/22265539
(6) http://www.ncbi.nlm.nih.gov/pubmed/22210102
(7) http://www.ncbi.nlm.nih.gov/pubmed/22180146
(8) http://www.ncbi.nlm.nih.gov/pubmed/22143540
(9) http://www.ncbi.nlm.nih.gov/pubmed/22107990
(10) http://www.ncbi.nlm.nih.gov/pubmed/21888504


Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Jiang (Rhizoma zingiberis officinalis)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Jiang (Rhizoma zingiberis officinalis)

A. Gan Jiang is also known as Ginger root. The acrid and warm herb has been use in TCM as an anti inflammation, anti coagulation of platelets, anti allergy, anti tumors and anti hair growth and warm the middle, purge coldness, improve circulation, rid of cold and pain of chest and of abdomen, treat lower back pain and chronic diarrhea etc., as it warms the Middle Burnner and the Lungs, rescues Yang, transforms Phlegm by enhancing the functions of lung, spleen and stomach channels.

Ingredients
1. 2-heptanol
2. 1,3,3-trimethyltricyclo[2,2,1,0] heptane
3. Tricycline
4. β-fenchene
5. β-pinene
6. 5-hepten-2-one-6-mehtyl
7. Myrcene
8. Octanal
9. α-thujene
10. Zingiberol
11. Zingiberene
12. α-curcumene
13. linalool
14. Cineole
15. Phellandrene
16. Camphene
17. Etc.


Side Effects
1. Do not use the herb in case of yin deficiency or vomiting with stomach heat.
2. Overdoses may cause heartburn, diarrhea and mouth irritation
3. Ginger may interact with blood thinning medicine such as aspirin, ibuprofen or warfarin
4. Do not use the herb in a large dose in newborn, children or if you are pregnant or breast feeding without consulting with the related field specialist.
5. Etc.


B. Sheng Jiang is also known as Fresh Ginger root. The acrid and cool herb has been use in TCM as an anti inflammation, anti coagulation of platelets, anti allergy, anti tumors, etc, and to promote flowing of bile, protect liver, stimulate cardiac function, inhibit platelet coagulation, prevent dizziness, improve auto-immune function,etc., as it promotes sweating, releases the Exterior; warms the Middle Burner and the Lungs, stops vomiting, calms cough by enhancing the functions of lung, spleen and stomach channels.


Ingredients
1. 2-heptanol
2. 1,3,3-trimethyltricyclo[2,2,1,0] heptane
3. Tricycline
4. β-fenchene
5. β-pinene
6. 5-hepten-2-one-6-mehtyl
7. Myrcene
8. Octanal
9. α-thujene
10. Zingiberol
11. Zingiberene
12. α-curcumene
13. linalool
14. Cineole
15. Phellandrene
16. Camphene
17. Etc.

Side Effects
1. Overdoses may cause heartburn, diarrhea and mouth irritation
2. Ginger may interact with blood thinning medicine such as aspirin, ibuprofen or warfarin
3. Do not use the herb in a large dose in newborn, children or if you are pregnant or breast feeding without consulting with the related field specialist.4. Etc.
C. Pao Jiang or Hei Jiang is also known as Quick-fried Ginger. The acrid and warm herb as been used in TCM to promote the digestive system, treat cold pain of chest and abdomen, flatulence, diarrhea. dysentry, stop bleeding, etc. as it warms the Middle Burnner and the Lungs, rescues Yang, transforms Phlegm by enhancing the functions of lung, spleen and stomach channels.


Health Benefits
1. Antidiabetic effects
In the investigation fo Ethyl acetate extract of ginger (EAG) for its antioxidant activity in terms of DPPH radical scavenging potential and antidiabetic activity, found that the antidiabetic effect of ginger was experimentally proved in the study and has concluded that the activity is initiated by antioxidant, antiglycation and potential to express or transport Glut4 receptors from internal vesicles, according to “Zingiber officinale extract exhibits antidiabetic potential via modulating glucose uptake, protein glycation and inhibiting adipocyte differentiation: an in vitro study” by Rani MP, Krishna MS, Padmakumari KP, Raghu KG, Sundaresan A.(1).

2. Antioxidant activities
In the study of the antioxidant activities of methanol extracts from the leaves, stems and rhizomes of two Zingiber officinale varieties (Halia Bentong and Halia Bara), found that The antioxidant activity and phenolic contents of the leaves as determined by the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) assay and the total amounts of phenolics and flavonoids were higher than those of the rhizomes and stems. On the other hand, the ferric reducing/antioxidant potential (FRAP) activity of the rhizomes was higher than that of the leaves. At low concentration the values of the leaves’ inhibition activity in both varieties were significantly higher than or comparable to those of the young rhizomes. Halia Bara had higher antioxidant activities as well as total contents of phenolic and flavonoid in comparison with Halia Bentong, according to “Antioxidant activities, total phenolics and flavonoids content in two varieties of Malaysia young ginger (Zingiber officinale Roscoe)” by Ghasemzadeh A, Jaafar HZ, Rahmat A.(2).

3. Anti cancer
In the review of the effect of Zingiber officinale Roscoe (ginger) as an adjuvant in cancer treatment, found that ginger possesses chemopreventive and antineoplastic properties. It is also reported to be effective in ameliorating the side effects of γ-radiation and of doxorubicin and cisplatin; to inhibit the efflux of anticancer drugs by P-glycoprotein (P-gp) and to possess chemosensitizing effects in certain neoplastic cells in vitro and in vivo, accoridng to “Zingiber officinale Roscoe (ginger) as an adjuvant in cancer treatment: a review” by Pereira MM, Haniadka R, Chacko PP, Palatty PL, Baliga MS.(3).

4. Anti-obesogenic and hypercholesterolemic effects
In the identification of key hepatic pathways targeted by anti-obsogenic ginger phytochemicals fed to mice, found that Dietary ginger phytochemicals target cholesterol metabolism and fatty acid oxidation in mice, with consequences, according to “Ginger phytochemicals mitigate the obesogenic effects of a high-fat diet in mice: a proteomic and biomarker network analysis” by Beattie JH, Nicol F, Gordon MJ, Reid MD, Cantlay L, Horgan GW, Kwun IS, Ahn JY, Ha TY.(4).

5. Antiinflammatory Effects
In the examination of an extract and several compounds of Zingiber officinale (ginger) tested in human bronchial epithelial cells (BEAS-2B cells) with respect to their effect on lipopolysaccharide (LPS)-induced secretion of the proinflammatory chemokine interleukin 8 (IL-8) and RANTES (regulated upon activation, normal T-cell expressed and secreted).
found that distinct ginger compounds could be used as antiinflammatory drugs in respiratory infections, according to “Antiinflammatory Effects of Ginger and Some of its Components in Human Bronchial Epithelial (BEAS-2B) Cells” by Podlogar JA, Verspohl EJ.(5).

6. Clotting activity
In the study of ginger proteases were extracted from fresh ginger rhizome by using phosphate buffer and subsequently purified by ion exchange chromatography, found that the ginger proteases exhibited a similar affinity for κ-casein and higher specificity with increasing temperature. Gel electrophoresis and mass spectra indicated that Ala90-Glu91 and His102-Leu103 of κ-casein were the preferred target bonds of ginger proteases. The milk clotting activity, affinity, and specificity toward κ-casein showed that ginger protease is a promising rennet-like protease that could be used in manufacturing cheese and oriental-style dairy foods, according to “Purification, characterization, and milk coagulating properties of ginger proteases” by Huang XW, Chen LJ, Luo YB, Guo HY, Ren FZ.(6).

7. Cognitive effects
In the investugation of male adult Wistar rats, administrated an alcoholic extract of ginger rhizome orally 14 days before and 21 days after the permanent occlusion of right middle cerebral artery (MCAO), found that cognitive function and neurons density in hippocampus of rats receiving ginger rhizome extract were improved while the brain infarct volume was decreased. The cognitive enhancing effect and neuroprotective effect occurred partly via the antioxidant activity of the extract. In conclusion, our study demonstrated the beneficial effect of ginger rhizome to protect against focal cerebral ischemia, according to “Zingiber officinale Mitigates Brain Damage and Improves Memory Impairment in Focal Cerebral Ischemic Rat” by Wattanathorn J, Jittiwat J, Tongun T, Muchimapura S, Ingkaninan K.(7).

8. Rheumatoid arthritis
In the comparison of the anti-inflammatory/anti-oxidant activity of these two plants in rat adjuvant-induced arthritis (AIA), indicated that the present study proves the anti-inflammatory/anti-oxidant activity of turmeric over ginger and indomethacin, which may have beneficial effects against rheumatoid arthritis onset/progression as shown in AIA rat model, according to “Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis” by Ramadan G, Al-Kahtani MA, El-Sayed WM.(8).

9. Gastroprotective effect
found that Ginger extract and polaprezinc both show anti-oxidation that consequently alleviates gastric mucosal damage and promotes ulcer healing, which together serve as effective mucosal protective agents, according to “Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats” by Ko JK, Leung CC.(9).

10. Lung cancer
In the observation of ethyl acetate fraction of ginger extract can inhibit the expression of the two prominent molecular targets of cancer, the human telomerase reverse transcriptase (hTERT) and c-Myc, in A549 lung cancer cells in a time- and concentration-dependent manner,
found that the treated cells exhibited diminished telomerase activity because of reduced protein production rather than direct inhibition of telomerase. The reduction of hTERT expression coincided with the reduction of c-Myc expression, which is one of the hTERT transcription factors; thus, the reduction in hTERT expression might be due in part to the decrease of c-Myc. As both telomerase inhibition and Myc inhibition are cancer-specific targets for cancer therapy, ginger extract might prove to be beneficial as a complementary agent in cancer prevention and maintenance therapy, according to “Ginger extract inhibits human telomerase reverse transcriptase and c-Myc expression in A549 lung cancer cells” by Tuntiwechapikul W, Taka T, Songsomboon C, Kaewtunjai N, Imsumran A, Makonkawkeyoon L, Pompimon W, Lee TR.(10).

11. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22261727
(2) http://www.ncbi.nlm.nih.gov/pubmed/20657444
(3) http://www.ncbi.nlm.nih.gov/pubmed/22006742
(4) http://www.ncbi.nlm.nih.gov/pubmed/21954187
(5) http://www.ncbi.nlm.nih.gov/pubmed/21698672
(6) http://www.ncbi.nlm.nih.gov/pubmed/21524515
(7) http://www.ncbi.nlm.nih.gov/pubmed/21197427
(8) http://www.ncbi.nlm.nih.gov/pubmed/21120596
(9) http://www.ncbi.nlm.nih.gov/pubmed/21091998
(10) http://www.ncbi.nlm.nih.gov/pubmed/21091248

Women Health: Overcome Infertility - Treatments of Uterine Lining Out Of Phase Caused By Blood Stagnation in The Yang Phase Of Menstrual Cycle

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse or can not carry the pregnancy to full term. It effects over 5 millions couple alone in the U. S. and many times more in the world, because of unawareness of treatments, only 10% seeks help from professional specialist. In fact, More than 40% of infertility of a couple is caused by male inability to fertilize.

                            
               The yang or luteal phase (about 12 -14 days)

When the egg is extruded into fallopian tube, liver transform yin energy to yang that trigger the yang ( progesterone) phrase. At this phrase, blood and qi move down ward, the endometrial lining become softer to prepare the implantation of the fertilized egg, if occurs.
In conventional medicine, at this phase corpus luteum starts to produce progesterone that triggers the softening of endometrial lining for fertilized egg implantation.

Uterine Lining Out Of Phase Caused By Blood Stagnation

Kidney yang is important in assisting liver in transform yin phase to the yang phase. As it rises to certain degree, it stimulates the softness of the uterine lining for the potential fertilized egg implantation. If the blood is stasis, it can not warm the uterine lining in providing the suitable environment for egg implantation even with the surge of yang, causing uterine lining out of phase.

I. Symptoms
1. Abdominal sever or stabling cramps and pain
2. Dark complexion
3. Bleeding with clot
4. Purple lips
5. Purple nails
6. petechia on skin
7. Etc.

II. Causes
1. Chronic inflammation
The prolonged period of inflammation causes blood static as a result of increasing blood flow to inflammation regions and distorting the immune system in fighting against foreign bacteria and virus function, leading to blood stagnation.
2. Liver function
Liver is vital for blood formation and waste removal. Abnormal function of liver causes old estrogen or other hormones as well as old blood remaining in the body's organs, leading to blood stagnation thus increasing the risk of menstrual irregularity and dysmenorrhrea.
3. Inability of respiratory function
If the lung is damaged for whatever reasons, it may affect the lung's ability to move qi in the pathway of the meridian, leading to blood stagnation in the reproductive region.
4. Stress and depression
Stress and depression caused by an unexpected event can affect the liver function in regulating the psychosocial symptoms of the nervous system and physical symptoms of blood formation, leading to liver qi and blood stagnation that contribute to symptoms of dysmenorrhrea.
5. Unhealthy diet
Unhealthy diet high in saturated and trans fat affect the blood and qi movement, because it causes the building up of cholesterol in the blood stream, thereby reducing the lung's function in regulating qi movement and the heart's function in blood circulation.

III. Treatments
A. With herbs
1. Wolfberry fruit - (gou qi zi)
Although wolfberry fruit is neutral herb, it has a function to promote yin and yang harmonization, thereby decreasing the dryness of lung qi which causes the blood stagnation causes of abdomen cramps and pain.

2. Polygonum multiflorum - (he shou wu)
Fleence is said to help improve the liver function by eliminating the liver toxin accumulation and expelling the "wind" from the skin, thereby increasing the liver function in blood formation and transportation.

3. Longan - (long yan rou)
Logan is warm in nature, it has been used in traditional Chinese medicine in treating yang deficiency causes of blood stagnation due to inability of the heart in blood circulation.

4. White mulberry fruit - (sang shen)
White mulberry fruit is a blood tonic herb, it helps to tonify the blood, resulting in lessening the risk of blood stagnation causes of abdominal cramps and pain.

5. Angelica Root - (dang gui)
Angellica root is considered as a queen herb in TCM, beside helping to tonifies the blood, regulates the women menstruation and promotes blood flow to the abdomen.

B. With acupuncture
1. ST36 (Zu san li)
2. SP6 (San yin jiao)
3. SP10 (Xue hai)
4. UB17 (Ge shu)
5. UB40 (Wei zhong)
6. Etc.

C. With foods
1. Turmeric
2. Garlic,
3. Scallion
4. Chive
5. Eggplant
6. Leek
7. Ginger
8. Etc.
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

General Health: Cerebral aneurysm Prevention - The Antioxidants

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years

Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                   Cerebral aneurysm

 Cerebral aneurysm is defined as a cerebrovascular disorder causes of the blood vessel to bulge or balloon out of the wall of a blood vessel as a result of the weaken of blood vessels and veins and occurred mostly at the bifurcations and branches of the large arteries located at the Circle of Willis.


                    The Prevention


Antioxidants against Cerebral Aneurysm
1. Bioflavonoids or vitamin P
Discovered by Szent-Gyorgyi and his colleagues back in the 1930`s. In Laboratory tests, B
bioflavonoids help to reduce the fragility and “permeability” in capillaries and prevent the clotting up of arterial as a result of oxidation.

2. Vitamins C and E, beta-carotene
Recent research findings have suggested that antioxidants such as vitamin C, E and beta carotene play an important role in the prevention of atherosclerosis. Data from animal studies showed they are able to prevent oxidative modification of low density lipoproteins (LDL).

3. Alpha-tocopherol
Alpha-tocopherol, a antioxidant found abundant in vitamin E, helps to decrease lipid peroxidation and platelet aggregation, adhesion and inflammatory. Epidemiological studies suggest that low levels of antioxidants are associated with increased risk for cardiovascular disease.

4. Vitamin C and E
Studies showed in take of 500mg of vitamin C and 400 IU of vitamin E helps to retard the progression of coronary atherosclersis.

5. Chlorophyl
Antioxidant chorophyll in the green algae shows to inhibit the chemical cadmium of smoking, by preventing from oxidation that cause building up of plaque along the walls of arteries.

6. Nitric oxide (NO)
Nitric oxide (NO), one of the antioxidant and peroxynitrite can inhibit pathways of oxygen radical generation, and, in turn, oxidants can inhibit NO synthesis from NOS.

7. Glutathione and vitamin E
Reduced form of glutathione may act as a first line of defense against oxidative stress during ischemia–reperfusion while vitamin E may act later on during severe oxidative stress by rendering resistance to the heart against the ischemic–reperfusion injury

8. 2-dithiole-3-thione (D3T)
Researcher found that in rat cardiac H9c2 cells, D3T and time-dependent induction of a number of cellular antioxidants and phase 2 enzymes, including catalase, reduced glutathione (GSH), GSH peroxidase, glutathione reductase (GR), GSH S-transferase (GST), and NADH:quinone oxidoreduc- tase-1 (NQO1) help to protect against H9c2 cell injury caused by various oxidants and simulated ischemia-reperfusion. D3T pretreatment also resulted in decreased intracellular accumulation of reactive oxygen in H9c2 cells after exposure to the oxidants as well as simulated ischemia-reperfusion.

9. Selenium
Deficiency of of a co-enzyme selenium, which is required in maintaining the glutathione redox cycle, also promote more susceptible to oxidative injure.

10. Thymus
The declining of the thymus function contributes a direct effect on the immune system due to diminish of quantity of T cells and immune factors.

11. Lipid peroxidation
Researchers found that lipid peroxidation are able to attack immune cells membrane, leading to the impediment of cells membrane activities, causing susceptibility diseases found in aging person.

12. NADHP oxidase
NADHP oxidase (nicotinamide adenine dinucleotide phosphate-oxidase) is a membrane-bound enzyme complex found in the plasma membrane. Free radicals cause damage to membrane, leading to diminish of its function in fighting against foreign invasion.

13. Cytokine
Free radicals damage immune cells that affect the function of cytokines in transmitting intercellular signals, leading to many disease states and conditions ranging from major depression and Alzheimer's disease to cancer.

14. Etc.

Women Health: The Obesity and Breast cancer Research and Studies of Body mass index on breast cancer in accordance with the life-stage of women

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of Body mass index on breast cancer in accordance with the life-stage of women


The prevalence of childbearing age obesity is wide spreading in US, approximately, 50% of them are either overweight [body mass index (BMI) 25-29.9 kg/m(2)] or obese (BMI ≥ 30 kg/m(2)).
Body mass index on breast cancer in accordance with the life-stage of women
Epidemiological evidence suggests that the impact of body weight on breast cancer risk should be heterogeneous throughout the life-stage of women. According to the study by the, posted in PubMed, at birth, high weight has been positively associated with an increased risk of breast cancer. While, the body mass index (a relative body weight; BMI kg/m(2)) has been inversely associated with breast cancer risk among pre-menopausal women. The inverse trend had been observed in both Western and Asian population, with a relatively lower percentage of obesity and higher percentage of leanness, suggested that the inverse trend could be explained not only by the protective impact due to obesity, but also by the increased risk of breast cancer due to leanness. Among post-menopausal women, however, an elevated BMI has been positively associated with the development of breast cancer, particularly in the cases of estrogen receptor-positive (ER+) and progesterone receptor-positive (PR+) tumors.

The Obesity' Research and Studies of Psychological interventions for overweight or obesity

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The Studies of  Psychological interventions for overweight or obesity

In the study to assess the effects of psychological interventions for overweight or obesity as a means of achieving sustained weight loss, indicated that people who are overweight or obese benefit from psychological interventions, particularly behavioural and cognitive-behavioural strategies, to enhance weight reduction. They are predominantly useful when combined with dietary and exercise strategies. The bulk of the evidence supports the use of behavioural and cognitive-behavioural strategies. Other psychological interventions are less rigorously evaluated for their efficacy as weight loss treatments(1).

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(1) "Psychological interventions for overweight or obesity" by Shaw K, O'Rourke P,Del Mar C, Kenardy J.