Friday, October 19, 2018

The Pungent Spice That Crucifies Breast Cancer Cells, Scientists Reveal

The finding of whole food medication by scientists all over the world to replace the single ingredient of a Western medicine for treatment of breast cancer with little or no side effect has been difficult due to no commercial benefits and patent right to producers.

Breast cancer is a medical and chronic condition characterized by irregular cells growth in the breast tissue.

In most cases, breast cancer (malignant breast neoplasm) starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk.

There are also rare cases that breast cancer starts in other areas of the breast.

According to statistic, in 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during the lifetime of women is 1/8.

Depending to the stage of cancer, women in the very early stage (increased risk of breast cancer) may only experience rusting at the nipple, bloody nipple drainage, a retracted, flattened nipple, particularly in those symptoms that do not go away in 2 weeks.


In the early stage of breast cancer, the tumor is smaller than the approximate size of a peanut (2 centimeters or smaller) and localized.

The survival rate of women diagnosed at this early stage is 100%.


In the breast cancer stage, according to the American Cancer Society, any of the following unusual changes in the breast can be a symptom of breast cancer such as swelling of all or part of the breast, skin irritation or dimpling. breast pain, nipple pain or the nipple turning inward. redness, scaliness, or thickening of the nipple or breast skin.

Therefore, regardless of breast cancer risk, self-examination is one of the best method to detect early breast cancer. All woman should be herself looking at and feeling each breast for possible lumps, distortions or swelling monthly,

Some researchers suggested that women with alternated genes and family history of breast cancers might be required to have their mammogram taken annually.


Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia.

The food or herb has been used popularly in traditional and Chinese medicine in treating common cold and flu to the Plague, blood pressure cholesterol levels, natural antibiotic, etc.

According to the study, administration of fresh Garlic Extract only exerted a significant effect in the inhibited colon and gastric cancer, but also stimulated cancer cell cycle arrest and alternated the morphology of MCF7 breast cancer cells.

In MCF7 human breast cancer cells, garlic constituent diallyl trisulfide have highly effective antitumor effects by suppressing viability of cultured MCF-7 and MCF-12a cells, through decreased the percent of cells in G(2)/M and induced apoptotic cell death.

According to the study by 201 South University Street, diallyl trisulfide, inhibited the expression of MDA-MB-231 and MCF-7 breast cancer cells, regardless of the state of estrogen in the tumors.

In a total of in 285 women (aged 25-65 years old) newly diagnosed with histopathologically confirmed breast cancer, dietary Allium Vegetables has a negative association between the consumption of raw onion and risk of breast cancer.


Dr. Roy N., the lead author at the Kerala Agricultural University, said, "Docking studies and ADMET evaluation revealed twelve compounds (isolated from garlic) to be active against the targets(breast cancer cell lines). All the compounds displayed highly negative dock scores which indicated good interactions".

These results suggested that the effectiveness of garlic in reduced risk and treatment of breast cancer is probably due to the existence of many phytochemicals found in the herb.

Adding garlic intake to your daily diet can ameliorate the risk of breast cancer substantially.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Fresh Garlic Extract Induces Growth Arrest and Morphological Differentiation of MCF7 Breast Cancer Cells by Modem S1, Dicarlo SE, Reddy TR. (PubMed)
(2) Garlic constituent diallyl trisulfide induced apoptosis in MCF7 human breast cancer cells by Malki A1, El-Saadani M, Sultan AS.(PubMed)
(3) Diallyl trisulfide, a chemopreventive agent from Allium vegetables, inhibits alpha-secretases in breast cancer cells by Kiesel VA1, Stan SD2. (PubMed)

Thursday, October 18, 2018

A Common and Kitchen Spice that Curbs Diabetes Naturally

Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate the glucose.

Type 1 diabetes is a congenital condition caused by the die-off of pancreas cells which are responsible for producing insulin, a hormone with a function to control the level of blood glucose.

A regular injection of insulin or insulin therapy is required daily in a patient who was born with the disease.

In contrast to type II diabetes, types 1 diabetes are not associated with dietary intake or unhealthy lifestyle that can cause an increase in glucose levels in the blood.

According to Diabetes Canada, patients with type 1 diabetes should aware of the number of insulin injections that are needed per day; the timing of insulin injections and the dose of insulin that is needed with each injection

The cause of type 1 diabetes is debatable, but some researchers found that most patients with type 1 diabetes are linked to abnormal body’s immune system overreaction to the cells that make insulin.

On the other hand, type 2 diabetes is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol due to unhealthy dietary and lifestyle selections.

In some cases, the diseases are also caused by allergic reactions of cells in the immune system.

If you experience some of the physical symptoms of frequent urination, excessive thirst, unexplained weight loss, nonrefractive visual impairment, and appetite problems, together with gastrointestinal symptoms such as stomach pain, heartburn, diarrhea, constipation, nausea and vomiting and mental symptoms of depression, emotion stress, sleeping difficulties,..... and suicidal ideation, you may have type 2 diabetes. Please check with your doctor as soon as possible(4).

According to the 2011 statistic from National Diabetes Information Clearinghouse (NDIC), among U.S. residents ages 65 years and older, 10.9 million, or 26.9 percent, have diabetes in 2010.

About 215,000 people younger than 20 years had diabetes—type 1 or type 2—in the United States in 2010.

And approximately, 1.9 million people ages 20 years or older were newly diagnosed with diabetes in 2010 in the United States.

For my years of practice and research, I do believe that intake of 1/4 tablespoon of Vietnamese cinnamon powder in the morning and evening have significant effects in keeping blood sugar in check.

In prediabetes with the morning reading of 6.9 mmol/L of a lady whom I know for 10 years, intake of the volume of cinnamon suggested above has managed to maintain her's the morning blood glucose at 5.3 mmol/L since.

Cinnamon, a kitchen spice used in many cultures, may have gained many believers, including medical professions because of its antidiabetic effect, through regulating the blood glucose levels in healthy and diabetic subjects.

According to herbalists, intake of 1/4 tsp. in the morning and evening may reduce the blood sugar significantly with little or no adverse side effects.

The herb has been used in herbal and traditional medicine as anti-fungal and bacteria activities and improves reproductive organ, prevents flatulence and intestinal cramping, treats indigestion, diarrhea, bad breath, headache, migraine, etc.(1).

In a total of 66 patients with type 2 diabetes study conducted by Xuhui District Central Hospital, researchers found that oral administration of cinnamon reduced significantly of blood triglyceride levels even in the low-dose group, after 3 months. (2).

Some researchers suggested that cinnamon extract improved fasting blood glucose levels and glucose tolerance without altering the insulin secretion may be attributed to its effects in lowering triglyceride and increasing liver glycogen content and improving insulin action in liver tissues(3).

Dr. Kim SH and Dr. Choung SY. told PubMed that “the effect of cinnamon significantly increases insulin sensitivity, reduces serum, and hepatic lipids, and improves hyperglycemia and hyperlipidemia possibly by regulating the PPAR-medicated glucose and lipid metabolism”(4).

Peroxisome proliferator-activated receptors (PPARs) including PPARα, PPARγ, and PPARβ/δ are receptors that reduce triglyceride level and regulate energy homeostasis.
In support of the above, chromium(Cr) and polyphenols found in cinnamon(Cinnamomum cassia) displayed a significant improvement of glucose, insulin, cholesterol, and HbA1c in patients with type 2 diabetes, according to a double-blind placebo-controlled study(7).

Unfortunately, according to the Western University of Health Sciences, even though consumption of cinnamon is associated with a statistically significant decrease in levels of fasting plasma glucose, but high degree of heterogeneity including quality and content may limit the ability to apply these results to patient care, due to the unclear preferred dose and duration of therapy(5).

Moreover, a randomized clinical trial in which 70 Patients with type II diabetes were assigned randomly into two groups (35 in cinnamon and 35 in placebo group) for the testing of the effect of cinnamon on the glucose level in blood, at the end of the experiment researchers found that there is an insignificant effect of using cinnamon on glucose level of diabetic patients and the herb should not be recommended to patients with type II diabetes depending on further studies(6).

Taken altogether, although there are some discrepancies involving cinnamon efficacy, I do believe that cinnamon in low dose is effective to control and manage the level of blood glucose in the patient with diabetes without altering the insulin level.

However, according to Dr. Georgakopoulou EA(7), oral intake of cinnamon may cause Stomatitis, and burning sensation in the mouth if it is taken in large amounts.

The traditional Chinese medicine also indicated that overdoses of cinnamon can be toxic and damage the liver(1).

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) @Popular Herbs -Cinnamon
(2) Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes by Lu T, Sheng H, Wu J, Cheng Y, Zhu J, Chen Y. (PubMed)
(3) Cinnamon extract improves insulin sensitivity in the brain and lowers liver fat in mouse models of obesity by Sartorius T1, Peter A2, Schulz N3, Drescher A2, Bergheim I4, Machann J5, Schick F6, Siegel-Axel D2, Schürmann A3, Weigert C1, Häring HU1, Hennige AM(PubMed)
(4) Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice by Kim SH1, Choung SY. (PubMed)
(5) Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis by Allen RW1, Schwartzman E, Baker WL, Coleman CI, Phung OJ. (PubMed)
(6) The Effect of Cinnamon on Glucose of Type II Diabetes Patients by Hasanzade F1, Toliat M2, Emami SA3, Emamimoghaadam Z(PubMed)
(7) Chromium and polyphenols from cinnamon improve insulin sensitivity by Anderson RA. (PubMed)
(8) Diabetes – The Symptoms by Kyle J. Norton

Wednesday, October 17, 2018

A Miracle Bean Which Is Better Than Probiotics and Prebiotics In the Optimization of Bowel Health

Whole food(herbal medicine), linking health benefits in the prevention, management, and treatment of diseases has played an important role in human history over many centuries.

The finding of whole food medication by renowned scientists all over the world to replace the single ingredient of Western medicine with little or no side effect has been difficult due to no commercial benefit and patent right to producers.

Bowel disease is a result of digestive dysfunction. People experience some minor gastrointestinal problems one in a while.

In some cases, digestive dysfunction can cause stomach discomforts such as bloated and sluggish. However, in serious cases, the digestive problem may lead to the development of irritable bowel syndrome, constipation, diarrhea, stomach-ache, nausea.

According to statistic, Irritable bowel syndrome (IBS) is the most common form of functional bowel syndrome, affecting approximately, 10–15% worldwide population.

In the US, about 2.4 and 3.5 million people suffer the syndrome annually.

Some researchers suggested that bowel disease may be associated with an imbalance of ratio of gut microbiota.

In other words, bowel disorder occurs when the bad bacteria have overgrowth in compared to the good one.

Overgrowth of C. difficile is associated to diarrhea. Long-term of unhealthy microbiota can lead to inflammatory bowel disease, inducing obesity, diabetes, and Cardiovascular Disease(5).

Dr. Miele L, the lead author said, "Gut microbiota has been recently established to have a contributory role in the development of cardiometabolic disorders, such as atherosclerosis, obesity, and type 2 diabetes" and "Growing interest has focused on the modulation of gut microbiota as a therapeutic strategy in cardiovascular diseases and metabolic disorders".


According to general belief, in taking probiotic may be considered as a healthy choice in improved gut health. However, according to recent study, "While evidence of the preventive and therapeutic effects of probiotic strains on diarrhoeal illness and other intestinal conditions is promising, the exact mechanisms of the beneficial effects are not fully understood" and "Recent studies have raised the question of whether non-viable probiotic strains can confer health benefits on the host by influencing the immune system".

Some health care professionals in services of patients with bladder and bowel diseases suggested that eating a balanced diet, drink enough fluids, limit the amount of alcohol you consume, chew your food well,...... and don’t miss meals may have potential effect in the contribution of a healthy bowel(7).

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to the Middle East.

With Nutrients of
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Vitamin A
6. Thiamine (Vitamin B1)
7. Riboflavin (Vitamin B2)
8. Niacin (Vitamin B3)
9. Pantothenic acid (B5)
10. Vitamin B6
11. Folate (Vitamin B9)
12. Vitamin C
13. Vitamin E
14. Vitamin K
15. Iron
16. Magnesium
17. Phosphorus
18. Potassium
19. Zinc

People who follow a typical American diet may express a certain problem in bowel movement, as a result of consuming high saturated fat, salt, sugar....... and less of fiber.

According to the University of Tasmania, diet not only affects food choice, satiety but also have a profound influence on bowel health.

As 15 participants.who participated in the study showed the trend of eating more processed snack foods (high energy, low fiber) after ceasing chickpea consumption(1).

In 27 free-living adults followed two randomized, crossover dietary interventions each of five weeks duration, Dr. Pittaway JK and research team said,"... a significant decrease in serum TC and LDL-C during the chickpea diet compared to the equivalent fiber wheat diet was partly due to unintentional changes in macronutrient intake occurring because of chickpea ingestion"(2).

The effect of chickpea in the promotion of bowel health may be the result of a high amount of dietary fiber found in the legume.

In the study of the effectiveness of probiotics, prebiotics, and dietary fiber in the treatment of FGD in the pediatric population, researchers suggested that administration of a fiber supplement is more effective than placebo for the treatment of childhood constipation(3).

In fact, fiber undergone partial or total fermentation after conscription in the distal small bowel and colon can lead to the production of short-chain fatty acids and gas, thereby affecting gastrointestinal function and sensation, the University of Michigan Health System, insisted(4).

And high-fiber diet showed to improve bowel function and health-related quality of life in patients with Crohn disease(8), according to the study of 2-group individuals diagnosed with the disease.

The results suggested that consuming foods with fiber score a significant effect in improved health-related quality of life and gastrointestinal function in compared to the same foods that without.


Taking all together, people who eat some portions of chickpea every day may improve the bowel health, regardless of types of diet.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources

(1) Chickpea supplementation in an Australian diet affects food choice, satiety and bowel health by Murty CM1, Pittaway JK, Ball MJ. (PubMed)
(2) Effects of a controlled diet supplemented with chickpeas on serum lipids, glucose tolerance, satiety and bowel function by Pittaway JK1, Ahuja KD, Robertson IK, Ball MJ. (PubMed)
(3) Probiotics, prebiotics, and dietary fiber in the management of functional gastrointestinal disorders by Horvath A1, Szajewska H.(PubMed)
(4) Fiber and functional gastrointestinal disorders by Eswaran S1, Muir J, Chey WD. (PubMed)
(5) Impact of Gut Microbiota on Obesity, Diabetes, and Cardiovascular Disease Risk by Miele L1,2, Giorgio V3, Alberelli MA4, De Candia E5, Gasbarrini A6, Grieco A(PubMed)
(6) Intestinal microbiota, diet, and health by Power SE1, O'Toole PW1, Stanton C2, Ross RP2, Fitzgerald GF(PubMed)
(7) Maintaining A Healthy Bowel(B&B)
(8) A high-fiber diet may improve bowel function and health-related quality of life in patients with Crohn disease by Brotherton CS1, Taylor AG, Bourguignon C, Anderson JG(PubMed)

Tuesday, October 16, 2018

Cayenne, The Spice That Blocks Airway Inflammation, Scientists Reveal



Scientists in numbers of institute suggested that cayenne, a kitchen spice may process a significant effect in inhibited airway inflammation, an important component of asthma, chronic obstructive pulmonary disease (COPD), and the various cough syndromes.

Conventional medicine has synthesized the effect of many of herbal plants' secondary metabolites, since the discovery of penicillin, the first antibiotic extracted from a very primitive plant, the fungus Penicillium, in 1928, used for the treatment of infection.

In years, herbalist is suspicious that these plants must contain some substances used together for healing purposes, without knowing the existence of every single ingredient.

Today, under microscopes of new technology, scientists discovered that effectiveness of herbal plants in the treatment of conditions and diseases are attributed to their's secondary metabolites.

Secondary metabolites are organic compounds, according to Massachusetts Institute of Technology that serve(7)
* As competitive weapons used against other bacteria, fungi, amoebae, plants, insects, and large animals.

* As metal transporting agents.

* As agents of symbiosis between microbes and plants, nematodes, insects, and higher animals.

* As sexual hormones; and

* As differentiation effectors.

for the survival of the plants producing them.

Following the herbalist food step and used herbal medicine as a fundamental source, conventional medicine has discovered numbers of single-ingredient medication, including quinine (from cinchona bark), and morphine (from the opium poppy)......

According to the Dr. Stanley F. Malamed, the lead author in the study of causative factors for acute asthma suggestion, "(In acute airway inflammation) Inflammation may occur as a result of either immunologic or nonimmunologic airway insults, which produce airway edema and cause the immigration of inflammatory cells into the lumen through the epithelium "(5)

Chronic airway inflammation can lead to chronic obstructive pulmonary disease (COPD), a progressive syndrome caused by expiratory airflow limitation as a result of airway remodeling, including an increase in airway smooth muscle (hyperplasia and hypertrophy),......

More importantly, the longer duration of airway inflammation may lower the lung function in induction of the worse of the bronchial hyperresponsiveness and symptoms(6)

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belongings to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions.

The herb or food has been used in traditional medicine to increase metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, ......., particularly, in treatment of inflammation caused by invasion of microbial organisms and allergens.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases, including inflammation.

Red pepper (Capsicum baccatum) extracts, according to the study by the Federal University of Rio Grande do Sul (UFRGS), exerted its anti-inflammatory properties through in inhibiting the neutrophil migration induced by carrageenan (Cg).

In animal study, the ethanolic and butanol extracts (200mg/kg, p.o.) presented a significant anti-inflammatory activity through their antioxidant phenolic and flavonoid compounds against oxidative and inflammation-related pathological processes, including airway inflammation.

β-Defensin, members of the antimicrobial peptide found in cayenne inhibited the expression of the mRNA of anti-inflammatory cytokine during the bacterial invasion, through stimulating immunomodulatory effects.

Other research suggested that anti-inflammatory effect induced by red pepper may be by inhibition of pro-inflammatory cytokine production at the inflammatory sites, such as upper airway.

Regular intake of Cayenne pepper can improve immune system against microbial infection and reduced risk of airway inflammation but overdose is found to induce toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Red Pepper (Capsicum baccatum) Extracts Present Anti-Inflammatory Effects In Vivo and Inhibit the Production of TNF-α and NO In Vitro by Allemand A1,2, Leonardi BF1, Zimmer AR1, Moreno S3, Romão PR2, Gosmann G1. (PubMed)
(2) Anti-inflammatory effects of red pepper (Capsicum baccatum) on carrageenan- and antigen-induced inflammation by Spiller F1, Alves MK, Vieira SM, Carvalho TA, Leite CE, Lunardelli A, Poloni JA, Cunha FQ, de Oliveira JR. (PubMed)
(3) Antioxidant and anti-inflammatory properties of Capsicum baccatum: from traditional use to scientific approach by Zimmer AR1, Leonardi B, Miron D, Schapoval E, Oliveira JR, Gosmann G.(PubMed)
(4) Defensin γ-thionin from Capsicum chinense has immunomodulatory effects on bovine mammary epithelial cells during Staphylococcus aureus internalization by Díaz-Murillo V1, Medina-Estrada I1, López-Meza JE1, Ochoa-Zarzosa A2. (PubMed)
(5) Learn more about Airway Inflammation(Science Direct)
(6) Why Does Airway Inflammation Persist? Is It Failure to Treat Early? by SØREN PEDERSEN(ATS Journals)
(7) The natural functions of secondary metabolites by Demain AL1, Fang A(PubMed)

Monday, October 15, 2018

Detoxification: How To Detox And Nourish Your Liver For Optimal Health, Citation Provided By PubMed


The western diet contains high saturated fat, trans fat, and other harmful substances such as sugar, caffeine, pesticides, addictive substances, and less in fruits and vegetables.

These types of harmful substances are toxic and induced a shift in microbiota composition in enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation(10).

Some researchers suggested that the escalating consumption of fat and sugar in Western countries are associated parallelly in an increased incidence of cardiovascular disease during the latter 20th century(10).
Also, according to the report in The American Journal of Pathology and studied mice module, Western diet altered the bile acid profile and elevated liver inflammation(12) as well as promoted other Western-pattern diet-related diseases, including nonalcoholic fatty liver disease, metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis(11).

Our body's detoxified functions try to get rid of them every day. When they fail, the toxins can cause a disruption of hormone production, damage to our body's detoxification organs and the immune system, leading to hormone imbalance and the development of chronic ailments.

The Natural Remedies Detox And Nourish Your Liver include
1. Milk thistle

Milk thistle, a flowering plant of the daisy family have been traditionally claimed in treating chronic liver disease.

The herbal medicine contains silymarin with impressive functions in protected liver function and expelled liver toxins.

In a study to compared Cirsium japonicum DC's flavonoids, liver protection against liver toxicity using carbon tetrachloride (CCl4) with silymarin as a positive control, researchers after taking into account of other co and founders found that silymarin exerts a clear hepatoprotective effects similar to those of Cirsium japonicum DC's flavonoids against toxins caused by injection of carbon tetrachloride (CCl4)(1)

Dr. Ma Q, the lead scientist said, "The results indicated that the pretreatment with C. japonicum flavonoids could significantly reverse CCl4-induced L02 cell viability decrease similarly to silymarin".

Silymarin is a mixture of flavonoids from Silybum marianum(milk thistle), a traditional European food plant with clear hepatoprotective effects.

2. Licorice
Licorice is a legume plant and native southern Europe and parts of Asia.

The herbal medicine contains a bioactive compound glycyrrhizin, which demonstrated a significant liver protective effect against liver toxins through suppression of hepatic stellate cell inactivation of liver fibrosis in some studies(3).

According to the seven-day intraperitoneal administration of glycyrrhizin (400 mg/kg/day) to 2- to 3-month-old male C57BL/6N mice (mean weight 27 g) against acetaminophen-induced liver damage observed by activity of alanine transaminase and aspartate aminotransferase, application of glycyrrhizin significantly reversed the increased levels of long-chain acylcarnitines in induction of liver damage and toxicity(2).

Further differentiation of this metabolomic assay, suggested that glycyrrhizin exert a significant protective effect against acetaminophen-induced liver damage induced by toxic acetaminophen through reversing fatty acid metabolism(2).

3. Tabebuia heptaphylla
Tabebuia heptaphylla is the botanical name of Pau d'Arco
The herbal plant contains alkaloids, flavonoids, sulfur, and essential oils which have a strong effect in enhanced helping to support the immune activity(4).

The herb displayed a strong hepaprotective effect against liver damage and toxicity, probably due to major bioactive compound flavonoids(4).

4. Stilingia root

Stilinga root not only strengthens the immune cells but also prevent and treating food allergies and eczema by stimulating the removal of toxins accumulation in the liver caused by long-term eating of preservatives, canned foods, fast foods, and excessive alcohol drinking.

According to the Scovill's compound syrup of sarsaparilla and stillingia, or, Blood and liver syrup for the cure of scrofula and all diseases of the blood and liver by A.L. Scovill & Co, stillingia root processes a strong hepaprotective effect against liver disease and liver toxins.

5. Prickly ash

Prickly ash is also known as toothache tree. It has been used traditionally as a digestive aid and to strengthen the nervous system. Prickly ash is considered as a tonic and stimulant herb for the liver and gallbladder.

As a holistic cleanser, Prickly ash eliminates toxins, including liver toxicity(5).


6. St. John Wort

St. John wort is also known as Tipton weed or Klamath weed.

The herb has been used popularly for its effect in ameliorated depression.

Major bioactive flavonoids and 3-O-coumaroylquinic acid process anti-inflammation and antioxidant effects in stimulating the immune system in fighting allergies and in protected liver against toxins(6).
.
Dr. Aydin A and colleagues in the study of the effects of St. John wort on hepatic ischemia suggested that application of H. perforatum on rat model exerts a strong liver protection against hepatic ischemia locally and systemically(6),

Its chromone glycosides also showed moderate hepatoprotective activity with EC(50) values of 160.2 microM and 217.7 microM, respectively, against tacrine-induced cytotoxicity in HepG2 cells(7).




7. Fennel
Fennel contains anethole, polymers and essential oil with function in improved liver and pancreas in the metabolism of fats and sugars.

The herbal medicine also has a strong effect in dissolved fat deposits of the body and restored damaged liver cells that cause jaundice, hepatitis and other liver disorders(8)(9).


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Hepatoprotective effect of flavonoids from Cirsium japonicum DC on hepatotoxicity in comparison with silymarin by Ma Q1, Wang LH, Jiang JG(PubMed)
(2) Targeted metabolomic study indicating glycyrrhizin’s protection against acetaminophen-induced liver damage through reversing fatty acid metabolism by Yu J, Jiang YS, Jiang Y, Peng YF, Sun Z, Dai XN, Cao QT, Sun YM, Han JC, Gao YJ(PubMed)
(3) Protective mechanisms of medicinal plants targeting hepatic stellate cell activation and extracellular matrix deposition in liver fibrosis by Florent Duval, Jorge E Moreno-Cuevas, María Teresa González-Garza,Carlos Rodríguez-Montalvo, and Delia Elva Cruz-Vega(PMC)
(4) Natural Products and Cancer Signaling: Isoprenoids, Polyphenols and Flavonoids by Chin-Lin Hsu*†, Gow-Chin Yen‡§1, in The Enzymes, 2014(Science Direct)
(5) Facts and benefits of Prickly Ash(Health Benefits Times)
(6) The effects of Hypericum perforatum on hepatic ischemia-reperfusion injury in rats by Aydin A, Sakrak O, Yilmaz TU, Kerem M(PubMed)
(7) Chromone glycosides and hepatoprotective constituents of Hypericum erectum by An RB1, Jeong GS, Beom JS, Sohn DH, Kim YC(PubMed)
(8) Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice by Warnet JM1, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR(PubMed)
(9) Protective mechanism of anethole on hepatic ischemia/reperfusion injury in mice by Cho HI1, Kim KM, Kwak JH, Lee SK, Lee SM(PubMed)
(10)Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation by Agus A1, Denizot J1, Thévenot J1,2, Martinez-Medina M1, Massier S1, Sauvanet P1,3, Bernalier-Donadille A4, Denis S2, Hofman P5, Bonnet R1,6, Billard E1,7, Barnich N(PubMed)
(11) Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis by Schierwagen R1, Maybüchen L1, Zimmer S2, Hittatiya K3, Bäck C4, Klein S1, Uschner FE1, Reul W1, Boor P5, Nickenig G2, Strassburg CP1, Trautwein C4, Plat J6, Lütjohann D7, Sauerbruch T1, Tacke F4, Trebicka J(PubMed)
(12) Western Diet Consumption May Increase Risk of Chronic Liver Inflammation in Men by All India | NDTV Food Desk | Updated: July 12, 2017, 16:05 IST(NDTV)

Sunday, October 14, 2018

Infectious Diseases: The Herbs That Suppress Over Growth of Candida, Scientists Say

Candida albicans are members of a large group of microorganism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract.

Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1).

According to joint study, in many cases, biofilm(microorganisms with cells stick to each other on a surface) formation(7) gene mutations(8) and overexpression of genes(9)(10) are often associated with increased candida resistance toward antifungal drugs.


Herbalism or phytotherapy is a traditional medicine used botany and plants for treatment of a variety of ailments. Today, it has become increasingly important for many scientists who intend to find the natural agents with the same effectiveness as conventional medicine without inducing serious side effects.

However, the finding of this whole food medication has been facing many obstacles including limited financial support, because, the discovery of such plants will provide no commercial benefit and patent right to producers.

According to Dr. Marjorie Murphy Cowan in the study of "Plant Products as Antimicrobial Agents" said, "While 25 to 50% of current pharmaceuticals are derived from plants, none are used as antimicrobials. Traditional healers have long used plants to prevent or cure infectious conditions" and " Plants are rich in a wide variety of secondary metabolites, such as tannins, terpenoids, alkaloids, and flavonoids, which have been found in vitro to have antimicrobial properties"(a).

Western medicine is trying to duplicate herbal successes with the synthetic version for the patent right without using the whole herb ingredients which have caused overexpression of serious adverse effects.

ROS species have duo functions that are well documented for playing an important role in our body as both beneficial and deleterious molecules in the expression of cytotoxicity against abnormal cells alternation and initiation of chronic ailments such as overgrowth of candida by causing an imbalance of the ratio among antioxidants and free radicals, respectively.

In free radical overexpression initiated overgrowth candida, certain herb-derived compounds exerted a strong antioxidant effect that targets Candida and restores health and balance.

According to the Jamia Millia Islamia, diallyl disulfide (DADS), an important organosulphur compound found in garlic inhibited the overgrowth of candida through decreasing activity of all antioxidant enzymes except catalase in Candida species antioxidant system.

These result suggested that application of diallyl disulfide (DADS) caused an increase of oxidative stress and damage to the fungal cells(b).


The Anti Over Growth of Candida Herbal Medicine
1. Berberis

Berberis is a genus of about 450-500 species of deciduous and evergreen shrubs from 1-5 m tall with thorny shoots, belongings to the family Berberidaceae, native to the temperate and subtropical regions of Europe, Asia, Africa, North America, and South America. Europe has a few species, and North America only two. The stem, root bark, and fruit of barberry containing alkaloids and berberine have been used in traditional medicine or dietary supplement, to treat fungal infections(270), Candida albicans(270), yeast(271), parasites, and bacterial/viral infections(270).

Berberine may also enhance the immune system through its antioxidant activity(272) by preventing candida yeasts from producing lipase(273)(274), an enzyme used to help them in colonization(274) and induced infection(274).

2. Clover(Trifolium)
Clover used as a spice in cuisines all over the world, is the aromatic dried flower buds of a tree in the Syzygium, belongings to the family Myrtaceae, native to Indonesia. Tellimagrandin II, in clover oil, exhibited significantly anti-herpesvirus(275) and anti-oxidant(275)(276) properties and antiseptic property through phytochemical eugenol(277) used in dentistry to relieve pain(277), prevent a bacterial infection(278) and boost the immune system(279).

3. Goldenseal((Hydrastis Canadensis)
Goldenseal is a perennial herb in the species of Hydrastis Canadensis, belongings to the family Ranunculaceae, native to southeastern Canada and the northeastern United States, used widely in traditional medicine to treat functional disorders of gastrointestinal(280), including atonic dyspepsia, chronic constipation, liver toxicity(281), etc.

Berberine, a compound found in goldenseal has demonstrated significant anti-fungal activity(282)(283)(284) by preventing candida yeasts from producing lipase, an enzyme involved in colonization.

4. Oregano(Origanum vulgare) Oil
Oregano is a common species of Origanum, belongings to the family Lamiaceae, native to warm-temperate western and southwestern Eurasia and the Mediterranean region.

Carvacrol, a monoterpenoid phenol phytochemical found in oregano oil inhibited the growth of several bacteria strains(285), including candida albicans due to its antimicrobial properties that disrupt the bacteria membrane(286).

5. Cinnamon
Cinnamon is a spice obtained from the inner bark of trees from the genus Cinnamomum, belongings to the family Lauraceae, used in traditional medicine to treat digestive system disorder(287)(289), insulin sensitive(288)(290) and enhance the immune system in regulated cells growth due to its antioxidant activity(290).

The cinnamon essential oil has antimicrobial properties(291)(292), which can prevent, limit or destroy the fungal overgrowth(293).

6. Allspice
Allspice also called Jamaica pepper is a spice of dried unripe fruit of Pimenta dioica, belongings to the family Myrtaceae, native to southern Mexico and Central America. The herb has been used in folk medicine in relieving indigestion and gas(294) and as a deodorant.

Phenylpropene found in allspice volatile oils has shown to exhibit an antimicrobial property(295), including Candida albicans(296)

7. Lavender(Lavandula angustifolia)
The lavender is a genus Lavandula of flowering plants in the mint family Lamiaceae, originated in Asia, used in herbal medicine to treat the microbial infection(297) for the skin and reduce inflammation(298)(299).

Its essential oil components linalool and linalyl acetate showed both fungistatic and fungicidal activity(300)(301) against C. albicans strains in reducing fungal progression and the spread of infection in host tissue(301).

8. Chamomile
Chamomile is a common name for several daisy-like plants, genus Matricaria belongings to the family Asteraceae, native to Europe and western Asia used in traditional medicine to aid sleep(302), treat diarrhea(303) and reduce oxidative stress(304). Chamomile containing the high amount of flavonoids is best known for its antioxidant(303), such as antiseptic and antibiotic properties against virus bacteria invasion(305)(306(307)) including candida ablicans(308).


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(a) Plant Products as Antimicrobial Agents by Marjorie Murphy Cowan(PMC)
(b) Effect of diallyldisulphide on an antioxidant enzyme system in Candida species by Yousuf S1, Ahmad A, Khan A, Manzoor N, Khan LA(PubMed)
(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMed)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicans by Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistant Candida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed)(247) The role of vitamin E in T-cell differentiation and the decrease of cellular immunity with aging.by Moriguchi S1.(PubMed)
(270) Antimicrobial activity of aqueous extracts and of berberine isolated from Berberis heterophylla by Freile ML1, Giannini F, Pucci G, Sturniolo A, Rodero L, Pucci O, Balzareti V, Enriz RD.(PubMed)
(271) Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin. Musumeci R1, Speciale A, Costanzo R, Annino A, Ragusa S, Rapisarda A, Pappalardo MS, Iauk L.(PubMed)
(272) In vitro biological assessment of Berberis vulgaris and its active constituent, berberine: antioxidants, anti-acetylcholinesterase, anti-diabetic and anticancer effects. Abd El-Wahab AE, Ghareeb DA1, Sarhan EE, Abu-Serie MM, El Demellawy MA.(PubMed)
(273) Inhibition of biofilm formation and lipase in Candida albicans by culture filtrate of Staphylococcus epidermidis in vitro. Bhattacharyya S1, Gupta P2, Banerjee G2, Jain A2, Singh M2.(PubMed)
(274) Differential Candida albicans lipase gene expression during alimentary tract colonization and infection. Schofield DA1, Westwater C, Warner T, Balish E.(PubMed)
(275) Medicinal Plants in Australia Volume 4: An Antipodean Apothecary
(276) Ellagitannin(Wikipedia)
(2377) Oil of clover(Wikipedia)
(278) Anti-virulence potential of eugenyl acetate against pathogenic bacteria of medical importance by Musthafa KS1, Voravuthikunchai SP.(PubMed)
(279) Immunomodulatory activity of geranial, geranial acetate, gingerol, and eugenol essential oils: evidence for humoral and cell-mediated responses. Farhath S1, Vijaya P1, Vimal M2.(PubMed)
(280) Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni by Cwikla C1, Schmidt K, Matthias A, Bone KM, Lehmann R, Tiralongo E.(PubMed)
(281) Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in ratsby Yamaura K1, Shimada M, Nakayama N, Ueno K.(PubMed)
(282) In vitro antifungal activity of the berberine and its synergism with fluconazole by Iwazaki RS1, Endo EH, Ueda-Nakamura T, Nakamura CV, Garcia LB, Filho BP.(PubMed)
(283) Synthesis of 13-(substituted benzyl) berberine and berberrubine derivatives as antifungal agents by Park KD1, Lee JH, Kim SH, Kang TH, Moon JS, Kim SU.(PubMed)
(284) Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans by Dhamgaye S1, Devaux F2, Vandeputte P3, Khandelwal NK4, Sanglard D3, Mukhopadhyay G5, Prasad R4.(PubMed)
(285) Effect of two monoterpene phenols on antioxidant defense system in Candida albicans by Khan A1, Ahmad A2, Ahmad Khan L3, Padoa CJ4, van Vuuren S5, Manzoor N6.(PubMed)
(286) Fungicidal activity of thymol and carvacrol by disrupting ergosterol biosynthesis and membrane integrity against Candidaby Ahmad A1, Khan A, Akhtar F, Yousuf S, Xess I, Khan LA, Manzoor N.(PubMed)
(287) Gastroprotective, cytoprotective and antioxidant effects of Oleum cinnamomi on ethanol induced damage by Ozbayer C1, Kurt H, Ozdemir Z, Tuncel T, Moheb Saadat S, Burukoglu D, Senturk H, Degirmenci I, Gunes HV.(PubMed)
(288) Cinnamon may have therapeutic benefits on lipid profile, liver enzymes, insulin resistance, and high-sensitivity C-reactive protein in nonalcoholic fatty liver disease patients by Askari F1, Rashidkhani B2, Hekmatdoost A3.(PubMed)
(289) Regular ingestion of cinnamon cortex pulveratus offers gastroprotective activity in mice by Tankam JM1, Sawada Y, Ito M.(PubMed)
(290) An overview on chemical composition, bioactivity, and processing of leaves of Cinnamomum tamala by Sharma V1, Rao LJ.(PubMed)
(291) Antimicrobial activities of commercial essential oils and their components against food-borne pathogens and food spoilage bacteria by Mith H1, Duré R2, Delcenserie V2, Zhiri A3, Daube G2, Clinquart A2.(PubMed)
(292) The antibacterial and antifungal activity of essential oils extracted from Guatemalan medicinal plants by Miller AB1, Cates RG, Lawrence M, Soria JA, Espinoza LV, Martinez JV, Arbizú DA.(PubMed)
(293) Anticandidal efficacy of cinnamon oil against planktonic and biofilm cultures of Candida parapsilosis and Candida orthopsilosis by Pires RH1, Montanari LB, Martins CH, Zaia JE, Almeida AM, Matsumoto MT, Mendes-Giannini MJ.(PubMed)
(294) Properties and Uses for Herbs and Spices
(295) Fumigant activity of (E)-anethole identified in Illicium verum fruit against Blattella germanica by Chang KS1, Ahn YJ.(PubMed)
(296) Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens by Botelho MA1, Nogueira NA, Bastos GM, Fonseca SG, Lemos TL, Matos FJ, Montenegro D, Heukelbach J, Rao VS, Brito GA.(PubMed)
(297) Hydrolates from lavender (Lavandula angustifolia) - their chemical composition as well as aromatic, antimicrobial and antioxidant properties by Prusinowska R1, Śmigielski K, Stobiecka A, Kunicka-Styczyńska A.(PubMed)
(298) Antioxidant capacity and total phenolic contents of oregano (Origanum vulgare), lavender (Lavandula angustifolia) and lemon balm (Melissa officinalis) from Romania by Spiridon I1, Colceru S, Anghel N, Teaca CA, Bodirlau R, Armatu A.(PubMed)
(299) Lavender essential oil inhalation suppresses allergic airway inflammation and mucous cell hyperplasia in a murine model of asthma by Ueno-Iio T1, Shibakura M2, Yokota K1, Aoe M1, Hyoda T1, Shinohata R1, Kanehiro A3, Tanimoto M3, Kataoka M1.(PubMed)
(300) Lavandula luisieri essential oil as a source of antifungal drugs by Zuzarte M1, Gonçalves MJ, Cruz MT, Cavaleiro C, Canhoto J, Vaz S, Pinto E, Salgueiro L.(PubMed)(301) Antifungal activity of phenolic-rich Lavandula multifida L. essential oil by Zuzarte M1, Vale-Silva L, Gonçalves MJ, Cavaleiro C, Vaz S, Canhoto J, Pinto E, Salgueiro L.(PubMed)
(302) Hypnotic activities of chamomile and passiflora extracts in sleep-disturbed rats by Shinomiya K1, Inoue T, Utsu Y, Tokunaga S, Masuoka T, Ohmori A, Kamei C.(PubMed)
(303) Antidiarrheal and antioxidant activities of chamomile (Matricaria recutita L.) decoction extract in rats by Sebai H1, Jabri MA2, Souli A3, Rtibi K3, Selmi S3, Tebourbi O4, El-Benna J5, Sakly M4.
(PubMed)
(304) Induction of heme oxygenase-1 by chamomile protects murine macrophages against oxidative stress by Bhaskaran N1, Shukla S, Kanwal R, Srivastava JK, Gupta S.(PubMed)
(305) Study of antimicrobial activity of chamomile oil by Aggag ME, Yousef RT.(PubMed)
(306) Phenolic acids profile, antioxidant and antibacterial activity of chamomile, common yarrow and immortelle (Asteraceae)by Mekinić IG, Skroza D, Ljubenkov I, Krstulović L, Možina SS, Katalinić V.(PubMed)
(307) A novel colorimetric broth microdilution method to determine the minimum inhibitory concentration (MIC) of antibiotics and essential oils against Helicobacter pylori by Weseler A1, Geiss HK, Saller R, Reichling J.(PubMed)
(308) All-natural composite wound dressing films of essential oilsencapsulated in sodium alginate with antimicrobial properties by Liakos I1, Rizzello L2, Scurr DJ3, Pompa PP2, Bayer IS4, Athanassiou A5.(PubMed)

Saturday, October 13, 2018

The Best Detoxification Diet, Scientists Suggest

American diet contains high saturated, trans fat, and other harmful substances such as sugar, caffeine, pesticides, addictive substances, and less in fruits and vegetables.

These types of harmful substances are toxic.

Some researchers suggested that diet and exposure to environmental toxins can damage the function of the mitochondria in cells in converting food to energy, affecting the organs function in protection of the body in all aspects.

The damage to mitochondria can increase overexpression of free-radicals in the induction of cytotoxicity to cells and tissue through a negative chain reaction

Foods that can detoxify our body against cytotoxicity include
1. Spinach
Spinach contains
* High levels of vitamin A, E, C, the free radical scavengers with function in reduced oxidative stress by improving production of antioxidant enzymes(1)(2).

* Numbers of trace minerals act as an antioxidant in inhibited ROS species such as iron, potassium, magnesium, zinc, and calcium(2). The presences of trace minerals in equate amount are vital for a healthy heart.

* Antioxidants, such as lutein and beta-carotene(3) strengthen our immune system and fight against the forming of free radicals.

People with kidney disease should not eat spinach, because it is rich with oxalates.

Without drinking a lot of water or juice, intake of the veggie will increase the risk of kidney stones formation.

2. Broccoli
Broccoli is high in vitamin C(1), an antioxidant that has a property in reduced the risk of inflammation and prevented forming of free radicals caused by toxins in our body.


The study shows that some of the chemicals such as indole 3, selenium and diindolymethane have anti-cancer properties and help to prevent and repair DNA damaging cells(4)(9).

3. Garlic
Garlic is a supernatural food. Besides having a proven record in preventing heart diseases, lower cholesterol level, elevated blood pressure(5), it also contains high amounts of allicin, an antibody that helps to reduce inflammation and fight off degeneration caused by virus, bacteria, strengthening our immune system(6) and forming of free radicals(7).

The sulfur element helps to rejuvenate our body by increasing the function of the liver in removing toxins(7).

4. Blackberry

Besides having a large amount of vitamin C and E(1) blackberry also contains anthocyanins and ellagic acid that work together in preventing inflammation, improving mental performance as well as strengthening the immune system(8). Its antioxidant function also removes the accumulation of heavy metal toxins in our body(9).

5. Mellon
Mellon contains high amounts of antioxidant enzyme(9), minerals(2) and the powerful antioxidant chlorophyll(9), which is rich in antioxidants, vital minerals such as magnesium, iron, potassium, calcium, and essential fatty acids(2) with functions in removed heavy metals accumulated in the brain and toxins in our kidney(10)

6. Green tea
Green tea balances the PH level(11) in the blood, it also contains polyphenolic catechins, a powerful antioxidant that strengthens the immune system(9), fights against free radicals building up and detoxes our body through urinary secretion(9)(12).

7. Cooked Tomato
Tomatoes contain high amounts of alpha and beta-carotene that help to strengthen the body's immune system fight off inflammation from bacteria and virus causing many types of chronic diseases(3).


The vegetable also contains lycopene(13), a powerful antioxidant that prevents the forming of free radicals caused by the accumulation of toxic substances in the body when working together with lutein(3). Be sure that the veggie is well cooked(14).

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


Sources
(1) Vitamin E and C supplementation reduces oxidative stress, improves antioxidant enzymes and positive muscle work in chronically loaded muscles of aged rats by Michael J. Ryan,1 Holly J. Dudash,1 Megan Docherty,1 Kenneth B. Geronilla,1,2 Brent A. Baker,2G. Gregory Haff,1 Robert G. Cutlip,2 and Stephen E. Alway(PubMed)
(2) Vitamins and minerals functioning as antioxidants with supplementation considerations Lee R. McDowell1 , Nancy Wilkinson, Rachel Madison and Tara Felix Department of Animal Sciences University of Florida
(3) Potential Role of Carotenoids as Antioxidants in Human Health and Disease by Joanna Fiedor* and Květoslava Burda(PubMed)
(4) Nutritional Epigenetic Regulators in the Field of Cancer by Michael Schnekenburger1, Marc Diederich2, in Epigenetic Cancer Therapy, 2015
(5) Garlic and Cardiovascular Disease: A Critical Review Khalid Rahman Gordon M. Lowe, The Journal of Nutrition, Volume 136, Issue 3, 1 March 2006, Pages 736S–740S,https://doi.org/10.1093/jn/136.3.736S
(6) The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention by Georgia Schäfer1 and Catherine H. Kaschula(PubMed)
(7) The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins by Rabinkov A1, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L(PubMed)
(8) Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days by Stoner GD1, Sardo C, Apseloff G, Mullet D, Wargo W, Pound V, Singh A, Sanders J, Aziz R, Casto B, Sun X(PubMed)
(9) Free radicals, antioxidants, and functional foods: Impact on human health by. Lobo, A. Patil, A. Phatak, and N. Chandra(PubMed)
(10) Toxicity, mechanism and health effects of some heavy metals by Monisha Jaishankar, Tenzin Tseten, Naresh Anbalagan, Blessy B. Mathew, and Krishnamurthy N. Beeregowda(PubMed)
(11) Evaluation of the pH and titratable acidity of teas commercially available in Brazilian market ORIGINAL | ORIGINAL Avaliação do pH e titrabilidade ácida de chás comercialmente disponíveis no mercado brasileiro
(12) 5 Kidney Cleansing Drinksby Dr. Group by Dr. Edward Group DC, NP, DACBN, DCBCN, DABFM
(13) Lycopene as A Carotenoid Provides Radioprotectant and Antioxidant Effects by Quenching Radiation-Induced Free Radical Singlet Oxygen: An Overview by Jalil Pirayesh Islamian, Ph.D.* and Habib Mehrali, M.Sc(PubMed)
(14) Cooking Tomatoes Boosts Disease-Fighting Power, Date: April 23, 2002 (by Cornell University)