Tongue cancer is a medical condition caused by irregular cell growth in the tissue of the tongue, due to the alternation of cell DNA.
Most cases of tongue cancer begin in the cells on the surface of the inner lining of the tongue. At the early stage, tongue cancer patients may not experience any size due to the very small of the tumors.
However, at the advanced stage, patients may experience symptoms of the persistent tongue and/or jaw pain as the tumor has pressed on the nearby nerve cells, a lump or tumor inside the mouth. a white or red patch on the gums, tongue, tonsil or lining in the mouth and persistent sore throat and difficulty swallowing or chewing.
If you have some of the above symptoms, please make sure to check with your doctor to rule out the possibility.
There are many risk factors associated with the disease, including long-term use of tobacco, excessive alcohol drinking, sun exposure to your lips.
Some researchers suggested that sexually transmitted virus human papillomavirus (HPV) and people with a weakened immune system also have been found in patients with tongue cancer.
The Cleveland Clinic wrote in the article of Oropharyngeal Human Papilloma Virus (HPV) Infection
"Human papillomavirus (HPV), commonly known as the virus that causes genital warts and cervical cancer in women, is increasingly being recognized now as a cause of infections that colonize the back of the mouth (throat or oropharynx), including the tongue base and tonsils, and potentially a cause of cancer of the head and neck".
The results strongly suggested that people who carry the HPV virus in their mouth are at an increased risk of tongue cancer, compared to those without.
Sinigrin is a phytochemical glucosinolate, belonging to the family of glucosides found abundantly in Brussels sprouts, broccoli, the seeds of black mustard, etc.
Scientists on the searching natural compound with the inhibitory activity against the tongue
carcinogenesis examined the effects of indole-3-carbinol (I3C) and sinigrin (SIN) on the initiation and post-initiation phases of tongue cancer.
Selected male ACI/N rats. induced tongue cancer by the injection of by 4-nitroquinoline 1-oxide (4-NQO) divided into
* Group 1 was given 4-NQO (10 ppm) in the drinking water for 12 weeks, starting at 7 weeks of age;
* Groups 2 and 3 were given 4-NQO and fed the diets containing I3C (1,000 ppm) and SIN (1,200 ppm) for 14 weeks, respectively, starting at 6 weeks of age;
* Groups 4 and 5 were given 4-NQO and then they were fed I3C and SIN containing diets for 23 weeks, respectively, starting one week after 4-NQO exposure;
* Groups 6 and 7 were given I3C and SIN alone, respectively, during the experiment; and
* Group 8 served as an untreated control.
At the end of the experiment at week 37, the incidence of tongue neoplasms (squamous cell papilloma and carcinoma) in group 2 (1/15, 7%), group 3 (1/15, 7%), group 4 (3/15, 20%) or group 5 (2/15, 13%) was significantly smaller than that in group 1 (12/17, 71%).
Group groups 2, 3, and 5 showed no tongue carcinomas developed. In other words, the injection of I3C and SIN restored the infected cell to healthy levels induced by the 4-NQO.
Group treated with I3C and SIN also showed reduced levels of the incidence of preneoplastic lesions such as hyperplasia and dysplasia.
In other words, I3C and SIN not only are effective against tongue cancer but also inhibit the progression of preneoplastic lesions of the tongue in group 2 (11/15, 73%), group 3 (10/15, 67%), group 4 (11/15, 73%) or group 5 (10/15, 67%) was significantly lower than that in group 1 (17/17, 100%) (P = 0.04 or P = 0.02).
Furthermore, There were no tongue neoplasms in rats of groups 6, 7, and 8.
Moreover, the Administration of I3C and SIN also caused significant decreases in the number and area of silver-stained nucleolar organizer regions protein (AgNORs) in the expression of in the tongue tumor pathology.
Dr. Tanaka T and colleagues wrote in the final report, " I3C and SIN inhibited rat tongue carcinogenesis in both the initiation and post-initiation phases, when administered in these respective phases together with, or following treatment with, 4-NQO".
Taken altogether, sinigrin (SIN) used alone or combined with I3C may be effective for the prevention and treatment of tongue cancer, pending to the confirmation of large sample size and multicenter human study.
Intake of SIN in a form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tonguecarcinogenesis by Tanaka T1, Kojima T, Morishita Y, Mori H. (PubMed)
(2) Oropharyngeal Human Papilloma Virus (HPV) Infection by (Cleveland Clinic)
Tuesday, April 30, 2019
Herbal Artichoke Normalizes the Level of Total Lipids Profile
Total lipids profile is a lab test that measures the abnormal levels of cholesterol and triglycerides that can lead to cardiovascular disease.
The healthy level of low-density cholesterol is less than 70 mg/dL for those in very high-risk patients, 100 mg/dL for high-risk patients and 130 mg/dL for individuals who are at low risk for coronary artery disease.
The healthy level of high-density cholesterol is any number that is higher than 40 mg/dl.
The healthy level of triglycerides (TG) is any number that is less than 150 mg/dl.
Where dl is milligrams per deciliter
Total cholesterol is the total amount of cholesterol in the blood using the formula HDL level + LDL level + 20 percent of triglyceride level from the results of total lipids profile.
The healthy levels of total cholesterol can be classified as follows
Optimal level: Less than 200 mg/dL
Normal high level: 200-239 mg/dL
High level: 240 mg/dL and above
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
On finding a natural remedy in the reducing risk and treatment of cardiovascular disease, researchers examined the artichoke in the subjects with hypercholesterolemia.
After 2 months of treatment, injection of artichoke showed a significant reduction in plasma total cholesterol (-19%), low-density lipoprotein cholesterol (-16%), non-high-density lipoprotein cholesterol (-19%) and triglyceride levels (-15%), compared to standard diet.
There were no side effects found in the tested subjects during the course of study.
Dr. Cicero AFG, the lead scientists wrote, " on the short-term, the tested nutraceutical has been shown to be well tolerated and effective, even if not containing any statin-like compound".
Dr. Santos HO in the study to investigate the effect of artichoke on lipid profile by searching the medical literature appraised the Cochrane, MEDLINE, and Web of Science databases, including articles published between 2000 and June 2018 on intervention in humans only.
The review on the selected studies suggested that
* ALE decreased serum LDL, total cholesterol and triglyceride concentrations.
* ALE showed no effect on the levels of HDL.
In details, according to the differentiation, ALE at doses of 2 to 3 g/d decreased 8-49 mg/dL for LDL concentration, 12-55 mg/dL for total cholesterol, and 11-51 mg/dL for triglycerides.
The improvement of the lipid profile of ALE was attributed to the components luteolin and chlorogenic acids found abundantly in artichoke.
Furthermore, the cardioprotective effect of ALE was associated with soluble fibers and inulin in the herb or food.
The findings clearly suggested that ALE protects the heart by improving the condition of the cluster associated with metabolic syndrome, particularly in blood cholesterol.
Taken together, artichoke may be considered a functional remedy for improving the lipid profile against diseases associated with hypercholesterolemia, pending to the confirmation of larger sample size and multicenter human study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Short-Term Effects of Dry Extracts of Artichokeand Berberis in Hypercholesterolemic Patients Without Cardiovascular Disease by Cicero AFG1, Fogacci F2, Bove M2, Giovannini M2, Veronesi M2, Borghi C. (PubMed)
(2) The effect of artichoke on lipid profile: A review of possible mechanisms of action by Santos HO1, Bueno AA2, Mota JF. (PubMed)
Monday, April 29, 2019
3,3'-Diindolylmethane, the Natural Ingredient for the Treatment of Chronic Diseases
Chronic diseases are a group of medical conditions most commonly associated with aging, including
arthritis, cardiovascular diseases such as heart attacks and stroke, cancer, diabetes, epilepsy and seizures, and obesity.
The exacted causes of chronic diseases are not identified. Aging, unhealthy lifestyle such as excessive alcohol drinking smoking, poor diet, lack of physical activity are the most common risk factors associated with the onset of the disease.
According to the joint study led by the Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 millions of the US population as many of them suffer from at least one chronic disease and the number is growing in the rapid rate.
Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.
According to the Centers for Disease Control, chronic diseases also are the major driver of health care costs accounted for nearly 75 percent of aggregate healthcare spending and increased absenteeism that impact workforce patterns.
Each chronic patient has cost the health care spending $5300 annually.
Believe it or not, chronic diseases in the US, chronic diseases are responsible for 7 out of 10 deaths yearly. In other words, chronic diseases kill more than 1.7 million Americans each year.
Some researchers suggested by changing unhealthy lifestyle pattern, chronic diseases may be preventable.
Dr. Walter C. Willett, the lead scientist in the concern about the risk chronic disease in poor lifestyle individuals wrote, "Several lines of evidence indicate that realistic modifications of diet and lifestyle can prevent most CAD, stroke, diabetes, colon cancer, and smoking-related cancers".
And, "Among U.S. adults, more than 90 percent of type 2 diabetes, 80 percent of CAD, 70 percent of stroke, and 70 percent of colon cancer are potentially preventable by a combination of nonsmoking, avoidance of overweight, moderate physical activity, healthy diet, and moderate alcohol consumption".
Researchers on finding a natural ingredient for the treatment of chronic diseases analyzed 3,3'-diindolylmethane (DIM) several biological activities on cellular and molecular levels against chronic diseases, including cancer.
DIM enhanced the function of the drug-metabolizing enzyme by blocking activity involved the promotion of cancer expression.
DIM affects multiple signaling pathways and target molecules which controls cell division, apoptosis, or angiogenesis deregulated in cancer cells.
DIM also prevented the development of hormone-dependent cancers.
Injection of DIM also was found to inhibit the onset of cardiovascular disease, obesity, and diabetes reduction through its antioxidant property in reducing oxidative stress caused by overexpression of free radical.
Dr. Licznerska B, the lead scientist after taking into account other factors wrote in the final report, "the current experimental data on the I3C and DIM activity and the results of clinical studies indicating their role in the prevention of chronic diseases".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W. (PubMed)
(2) An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach to Public Health by Wullianallur Raghupathi1 and Viju Raghupathi. (PubMed)
(3) Prevention of Chronic Disease by Means of Diet and Lifestyle Changes by Walter C. Willett, Jeffrey P. Koplan, Rachel Nugent, Courtenay Dusenbury, Pekka Puska, and Thomas A. Gaziano. (PubMed)
arthritis, cardiovascular diseases such as heart attacks and stroke, cancer, diabetes, epilepsy and seizures, and obesity.
The exacted causes of chronic diseases are not identified. Aging, unhealthy lifestyle such as excessive alcohol drinking smoking, poor diet, lack of physical activity are the most common risk factors associated with the onset of the disease.
According to the joint study led by the Fordham University, chronic diseases are among the most prevalent and costly health conditions in the US, affecting over 133 millions of the US population as many of them suffer from at least one chronic disease and the number is growing in the rapid rate.
Some chronic diseases such as cancer have been found to be the leading causes of hospitalization, long-term disability, reduced quality of life, and death.
According to the Centers for Disease Control, chronic diseases also are the major driver of health care costs accounted for nearly 75 percent of aggregate healthcare spending and increased absenteeism that impact workforce patterns.
Each chronic patient has cost the health care spending $5300 annually.
Believe it or not, chronic diseases in the US, chronic diseases are responsible for 7 out of 10 deaths yearly. In other words, chronic diseases kill more than 1.7 million Americans each year.
Some researchers suggested by changing unhealthy lifestyle pattern, chronic diseases may be preventable.
Dr. Walter C. Willett, the lead scientist in the concern about the risk chronic disease in poor lifestyle individuals wrote, "Several lines of evidence indicate that realistic modifications of diet and lifestyle can prevent most CAD, stroke, diabetes, colon cancer, and smoking-related cancers".
And, "Among U.S. adults, more than 90 percent of type 2 diabetes, 80 percent of CAD, 70 percent of stroke, and 70 percent of colon cancer are potentially preventable by a combination of nonsmoking, avoidance of overweight, moderate physical activity, healthy diet, and moderate alcohol consumption".
Researchers on finding a natural ingredient for the treatment of chronic diseases analyzed 3,3'-diindolylmethane (DIM) several biological activities on cellular and molecular levels against chronic diseases, including cancer.
DIM enhanced the function of the drug-metabolizing enzyme by blocking activity involved the promotion of cancer expression.
DIM affects multiple signaling pathways and target molecules which controls cell division, apoptosis, or angiogenesis deregulated in cancer cells.
DIM also prevented the development of hormone-dependent cancers.
Injection of DIM also was found to inhibit the onset of cardiovascular disease, obesity, and diabetes reduction through its antioxidant property in reducing oxidative stress caused by overexpression of free radical.
Dr. Licznerska B, the lead scientist after taking into account other factors wrote in the final report, "the current experimental data on the I3C and DIM activity and the results of clinical studies indicating their role in the prevention of chronic diseases".
Taken altogether, 3,3'-Diindolylmethane derived from the digestion of indole-3-carbinol may be considered a supplement for the prevention and treatment of chronic diseases, pending to the confirmation of the larger sample size and multicenter human study.
Intake of 3,3'-diindolylmethane in form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W. (PubMed)
(2) An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach to Public Health by Wullianallur Raghupathi1 and Viju Raghupathi. (PubMed)
(3) Prevention of Chronic Disease by Means of Diet and Lifestyle Changes by Walter C. Willett, Jeffrey P. Koplan, Rachel Nugent, Courtenay Dusenbury, Pekka Puska, and Thomas A. Gaziano. (PubMed)
Phytochemical Sinigrin Protects Our Body Against the Onset of Chronic Inflammatory Diseases
Sinigrin may be used as a natural and bioactive compound against diseases associated with chronic inflammation, according to studies.
Acute inflammation that lasts a day or 2 mostly associated with proinflammatory response to tissue injury, usually appearing within minutes or hours, depending on the severity of the damage.
In other words, in the acute phase of inflammation, the immune systematic response of the macrophages stimulate the process of coagulation to cover the wound or injure and production of the inflammatory cytokines to destroy the foreign pathogens which try to enter the body through the wound or injury.
Most common symptoms of acute inflammation are a pain, redness, loss of function, swelling and heat.
In the acute phase of inflammation, overproduction of proinflammatory cytokines which protect our body against the foreign invasion may damage the nearby tissues and death of the healthy cell, leading to the abnormal formation of scars.
Chronic inflammation is a medical condition caused by the inability of the immune system to kill off all pathogens in the acute phase of inflammation, leading to the compromise of the immune system.
Chronic inflammation is a leading cause of various types of disease, including cancer, diabetes, cardiovascular disease, and arthritis.
Unlike the symptoms in the acute inflammation, symptoms of chronic inflammation are totally depending to the types of disease and location of the inflammation, including fatigue and unintended weight loss and loss of appetite in cancer, chest pain in chronic lung disease, and joint pain in RA.
On finding a natural compound for the treatment of diseases associated with chronic inflammation, researchers investigated the effect of sinigrin on macrophage function.
In RAW 264.7 cells in a concentration-dependent manner, sinigrin inhibited lipopolysaccharide (LPS)-induced production of proinflammatory cytokines including nitric oxide (NO) and the expression of COX-2 and prostaglandin E2 (PGE2).
Injection of sinigrin significantly suppressed the production of pro-inflammatory tumor necrosis factor (TNF)-α and interleukin (IL)-6 by suppressing the protein in cellular response to oxidative stress and stimuli.
Additional analysis, sinigrin also processed a significant effect in inhibiting genes expression involved the mediation of innate immunity and inflammatory responses.
Dr. Lee HW, the lead scientist, wrote in the final report, " Our findings also provide evidence that the pharmacological modulation of sinigrin could have an anti-inflammatory effect".
In lipopolysaccharide (LPS)-induced neuroinflammation, AITC protected the microglial cells against neuroinflammation by inhibiting the cellular response against oxidative stress induced the production of pro-inflammatory cytokines such as cyclooxygenase-2 (COX-2) expression, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), prostaglandin E2 (PGE2).
In other words, AITC protects neuroblastoma cells by controlling with JNK/NF-κB/TNF-α cross-linking associated with the expression of the gene in inducing apoptosis.
Dr. Subedi L, the lead scientist, after taking into account co and confounders said, "These findings provide novel insights into the anti-neuroinflammatory effects of AITC on microglial cells, which may have clinical significance in neurodegeneration".
Taken altogether, sinigrin may be considered a functional supplement for the prevention and treatment of diseases associated with chronic inflammation, pending to the confirmation of large sample size and multicenter human study.
However, intake of bioactive in the form of supplement should be taken with extreme care, as liver toxicity may be induced if overdosed.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sinigrin inhibits production of inflammatory mediators by suppressing NF-κB/MAPK pathways or NLRP3 inflammasome activation in macrophages by Lee HW1, Lee CG1, Rhee DK1, Um SH2, Pyo S. (PubMed)
(2) Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling by Subedi L1, Venkatesan R2, Kim SY. (PubMed)
Acute inflammation that lasts a day or 2 mostly associated with proinflammatory response to tissue injury, usually appearing within minutes or hours, depending on the severity of the damage.
In other words, in the acute phase of inflammation, the immune systematic response of the macrophages stimulate the process of coagulation to cover the wound or injure and production of the inflammatory cytokines to destroy the foreign pathogens which try to enter the body through the wound or injury.
Most common symptoms of acute inflammation are a pain, redness, loss of function, swelling and heat.
In the acute phase of inflammation, overproduction of proinflammatory cytokines which protect our body against the foreign invasion may damage the nearby tissues and death of the healthy cell, leading to the abnormal formation of scars.
Chronic inflammation is a medical condition caused by the inability of the immune system to kill off all pathogens in the acute phase of inflammation, leading to the compromise of the immune system.
Chronic inflammation is a leading cause of various types of disease, including cancer, diabetes, cardiovascular disease, and arthritis.
Unlike the symptoms in the acute inflammation, symptoms of chronic inflammation are totally depending to the types of disease and location of the inflammation, including fatigue and unintended weight loss and loss of appetite in cancer, chest pain in chronic lung disease, and joint pain in RA.
On finding a natural compound for the treatment of diseases associated with chronic inflammation, researchers investigated the effect of sinigrin on macrophage function.
In RAW 264.7 cells in a concentration-dependent manner, sinigrin inhibited lipopolysaccharide (LPS)-induced production of proinflammatory cytokines including nitric oxide (NO) and the expression of COX-2 and prostaglandin E2 (PGE2).
Injection of sinigrin significantly suppressed the production of pro-inflammatory tumor necrosis factor (TNF)-α and interleukin (IL)-6 by suppressing the protein in cellular response to oxidative stress and stimuli.
Additional analysis, sinigrin also processed a significant effect in inhibiting genes expression involved the mediation of innate immunity and inflammatory responses.
Dr. Lee HW, the lead scientist, wrote in the final report, " Our findings also provide evidence that the pharmacological modulation of sinigrin could have an anti-inflammatory effect".
In lipopolysaccharide (LPS)-induced neuroinflammation, AITC protected the microglial cells against neuroinflammation by inhibiting the cellular response against oxidative stress induced the production of pro-inflammatory cytokines such as cyclooxygenase-2 (COX-2) expression, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), prostaglandin E2 (PGE2).
In other words, AITC protects neuroblastoma cells by controlling with JNK/NF-κB/TNF-α cross-linking associated with the expression of the gene in inducing apoptosis.
Dr. Subedi L, the lead scientist, after taking into account co and confounders said, "These findings provide novel insights into the anti-neuroinflammatory effects of AITC on microglial cells, which may have clinical significance in neurodegeneration".
Taken altogether, sinigrin may be considered a functional supplement for the prevention and treatment of diseases associated with chronic inflammation, pending to the confirmation of large sample size and multicenter human study.
However, intake of bioactive in the form of supplement should be taken with extreme care, as liver toxicity may be induced if overdosed.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Sinigrin inhibits production of inflammatory mediators by suppressing NF-κB/MAPK pathways or NLRP3 inflammasome activation in macrophages by Lee HW1, Lee CG1, Rhee DK1, Um SH2, Pyo S. (PubMed)
(2) Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling by Subedi L1, Venkatesan R2, Kim SY. (PubMed)
Sunday, April 28, 2019
Ginger, The Best Gastroprotective Functional Pungent Spice
Gastrointestinal disorders are medical conditions, involving the esophagus, stomach, small intestine, large intestine, and rectum.
Most common gastrointestinal disorders are very mild associated with digestive discomforts that can be resolved in a few days.
The gastroprotective effect is an action that protects the gastrointestinal tract against the onset of any disease, including infection and inflammation.
The causes of digestive disorders can be multiple. Most gastrointestinal disorders caused directly by the disorders of the digestive system such as poor diet pattern. However, long-term use of certain medication can also induce gastrointestinal disorders, including Manticholinergic medication, non-steroidal anti-inflammatory drugs, and antibiotics.
In the searching a diet therapy that can reverse and protect the digestive system against gastrointestinal disorder, researchers at the University of Florida, wrote, "Diet therapy through the elimination of offending foods such as wheat gluten or lactose, or inclusion of specialized products such as medium chain triglycerides or elemental formulas, can sustain nutritional status".
And "Dietary components such as insoluble fiber appear to have physiologic effects, while soluble fibers may have metabolic effects important to diabetes and cardiovascular disease".
Additionally, in the differentiation of types of diet may have a direct contribution to reduce the risk of gastrointestinal disorders, the authors continued, "Avoiding offending foods by Crohn's patients is an acceptable practice as long as entire categories of foods are not deleted. Avoiding all foods containing gluten from wheat, rye, barley, and oats, however, is a crucial prerequisite to recovery from celiac disease. Gluten is commonly used as a stabilizer, emulsifier, and extender in the food industry and is not always shown on food labels. Careful consultation with a registered dietitian can identify hidden sources of gluten in the diet.".
These results clearly indicated, depending on types of gastrointestinal disorder, diet therapy with modification could have a strong impact on the prevention of the onset of the disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural whole food which processes gastrointestinal protective effects, researchers looked into rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger, an important kitchen spice, possessing myriad health benefits.
In laboratory animals., ginger was shown to be effective in preventing gastric ulcers induced by nonsteroidal anti-inflammatory drugs [NSAIDs like indomethacin, aspirin], reserpine, ethanol, and acetic acid and Helicobacter pylori-induced gastric ulcerations.
The gastroprotective efficacy of ginger was attributed to its free radical scavenging, antioxidant; inhibition of lipid peroxidation activities.
Furthermore, in the evaluation of the gastroprotective effect to examine the turmeric (Curcuma longa) and ginger (Zingiber officianale), researchers conducted a study in the ethanol-induced ulcers animal model.
Selected rats were given 100, 500 and 1000 mg/kg body weight orally.
Application of TEO and GEO inhibited ulcer caused by injection of ethanol by 84.7% and 85.1%, respectively, as seen from the ulcer index.
The reduced antioxidant enzymes such as GPx, SOD, catalase and GSH produced by alcohol administration were significantly (p<0.001) increased by simultaneous administration of TEO and GEO.
Ethanol-induced lesions such as necrosis, erosion, and hemorrhage of the stomach wall were significantly reduced after oral administration of essential oils.
These results strongly suggested, turmeric and ginger exerted a significant gastroprotective effect against gastrointestinal lesions with no side effects.
Taken altogether, ginger may be considered a functional for the prevention and combined with primary medicine for the treatment of gastrointestinal disorders,
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe) by Haniadka R1, Saldanha E, Sunita V, Palatty PL, Fayad R, Baliga MS. (PubMed)
(2) Gastroprotective activity of essential oils from turmeric and ginger by Liju VB, Jeena K, Kuttan R. (PubMed)
(3) Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats by Ko JK1, Leung CC. (PubMed)
(4) Dietary therapy in gastrointestinal disease by Anderson CR1, Cerda JJ. (PubMed)
Most common gastrointestinal disorders are very mild associated with digestive discomforts that can be resolved in a few days.
The gastroprotective effect is an action that protects the gastrointestinal tract against the onset of any disease, including infection and inflammation.
The causes of digestive disorders can be multiple. Most gastrointestinal disorders caused directly by the disorders of the digestive system such as poor diet pattern. However, long-term use of certain medication can also induce gastrointestinal disorders, including Manticholinergic medication, non-steroidal anti-inflammatory drugs, and antibiotics.
In the searching a diet therapy that can reverse and protect the digestive system against gastrointestinal disorder, researchers at the University of Florida, wrote, "Diet therapy through the elimination of offending foods such as wheat gluten or lactose, or inclusion of specialized products such as medium chain triglycerides or elemental formulas, can sustain nutritional status".
And "Dietary components such as insoluble fiber appear to have physiologic effects, while soluble fibers may have metabolic effects important to diabetes and cardiovascular disease".
Additionally, in the differentiation of types of diet may have a direct contribution to reduce the risk of gastrointestinal disorders, the authors continued, "Avoiding offending foods by Crohn's patients is an acceptable practice as long as entire categories of foods are not deleted. Avoiding all foods containing gluten from wheat, rye, barley, and oats, however, is a crucial prerequisite to recovery from celiac disease. Gluten is commonly used as a stabilizer, emulsifier, and extender in the food industry and is not always shown on food labels. Careful consultation with a registered dietitian can identify hidden sources of gluten in the diet.".
These results clearly indicated, depending on types of gastrointestinal disorder, diet therapy with modification could have a strong impact on the prevention of the onset of the disease.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural whole food which processes gastrointestinal protective effects, researchers looked into rhizomes of Zingiber officinale Roscoe (Zingiberaceae), commonly known as ginger, an important kitchen spice, possessing myriad health benefits.
In laboratory animals., ginger was shown to be effective in preventing gastric ulcers induced by nonsteroidal anti-inflammatory drugs [NSAIDs like indomethacin, aspirin], reserpine, ethanol, and acetic acid and Helicobacter pylori-induced gastric ulcerations.
The gastroprotective efficacy of ginger was attributed to its free radical scavenging, antioxidant; inhibition of lipid peroxidation activities.
Furthermore, in the evaluation of the gastroprotective effect to examine the turmeric (Curcuma longa) and ginger (Zingiber officianale), researchers conducted a study in the ethanol-induced ulcers animal model.
Selected rats were given 100, 500 and 1000 mg/kg body weight orally.
Application of TEO and GEO inhibited ulcer caused by injection of ethanol by 84.7% and 85.1%, respectively, as seen from the ulcer index.
The reduced antioxidant enzymes such as GPx, SOD, catalase and GSH produced by alcohol administration were significantly (p<0.001) increased by simultaneous administration of TEO and GEO.
Ethanol-induced lesions such as necrosis, erosion, and hemorrhage of the stomach wall were significantly reduced after oral administration of essential oils.
These results strongly suggested, turmeric and ginger exerted a significant gastroprotective effect against gastrointestinal lesions with no side effects.
Taken altogether, ginger may be considered a functional for the prevention and combined with primary medicine for the treatment of gastrointestinal disorders,
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe) by Haniadka R1, Saldanha E, Sunita V, Palatty PL, Fayad R, Baliga MS. (PubMed)
(2) Gastroprotective activity of essential oils from turmeric and ginger by Liju VB, Jeena K, Kuttan R. (PubMed)
(3) Ginger extract and polaprezinc exert gastroprotective actions by anti-oxidant and growth factor modulating effects in rats by Ko JK1, Leung CC. (PubMed)
(4) Dietary therapy in gastrointestinal disease by Anderson CR1, Cerda JJ. (PubMed)
Celery, the Potent Anti Hypertension Functional Food with No Side Effects
Celery, the tasty vegetable may be used for the prevention and treatment of hypertension, some scientists suggested.
Hypertension is the most common syndrome in the Western world caused by abnormally high blood pressure.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable.
The veggie can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.
There is no single cause of hypertension. Epidemiological studies suggested an unhealthy lifestyle such as a diet with high saturated and trans fat, red meat and processed food and low fruits and vegetables, smoking, overweight and obesity contributes to the onset of hypertension.
In the differentiate the correlation between the Western diet which had been promoted by the industries over the last many decades and the risk of hypertension, researchers indicated, the Western diet is one of major culprit associated to the rise of high blood pressure incidence in the adults of the Western world.
In other words, if you follow the Western diet, you will have chronic high blood pressure developed in some points during your lifetime. Luckily, if you make a change to a healthy diet, your risk of high blood pressure is reduced.
Dr. Hojhabrimanesh A, the lead scientists in the metabolic team at the Shiraz University of Medical Sciences in the classification of dietary risk of hypertension wrote, " three major dietary patterns were identified, among which only the Western pattern (abundant in soft drinks, sweets and desserts, salt, mayonnaise, tea and coffee, salty snacks, high-fat dairy products, French fries, and red or processed meats) had a significant association with BP".
And " After adjusting for potential confounders in the analysis of covariance models, multivariable adjusted means of the systolic and mean BP of subjects in the highest tertile of the Western pattern score were significantly higher than those in the lowest tertile".
With an aim to find a natural ingredient or whole food for the prevention and treatment of hypertension, researchers at the Mashhad University of Medical Sciences assessed the effects of different celery (Apium graveolens) seed extracts on blood pressure (BP).
In animal study, elected rats were induced hypertension by the injection of deoxycorticosterone acetate.
The hexanic, methanolic, and aqueous-ethanolic extracts were administered intraperitoneally to examine the tested animal antihypertensive effects on BP and heart rate (HR), compared to the spironolactone as a diuretic and positive control.
Application of all extracts decreased BP and increased the HR in hypertensive rats, with no effect on normotensive rats.
In volume analysis, administration of 300 mg/kg of hexanic, methanolic, and aqueous-ethanolic (20/80, v/v) extracts of the celery seed caused 38, 24, and 23 mmHg reduction in BP and 60, 25, and 27 beats per minute increase in the HR, respectively.
The effects of celery seed extracted were found to process high amounts of n-butylphthalide (NBP), which has been proven epidemiologically an antihypertensive constituent.
According to the HPLC analysis data revealed that the hexanic extract demonstrated the greatest effect in normalizing the high blood pressure due to the containing the 3.7 and 4 times NBP greater than that of the methanolic and aqueous-ethanolic extracts.
Dr. Moghadam MH, the lead scientist wrote in the final report, " celery seed extracts have antihypertensive properties, which appears to be attributable to the actions of its active hydrophobic constitutes such as NBP" and, "can be considered an antihypertensive agent in the chronic treatment of elevated BP".
Additionally, in the study to evaluate the inverse associations of overall vegetable intake to blood pressure (BP); whether such relations prevail for both raw and cooked vegetables, researchers launched a review of the report of the cross-sectional associations of vegetable intakes with BP for 2195 Americans ages 40-59 in the International Study of Macro/Micronutrients and Blood Pressure (INTERMAP).
According to the multiple linear regression assay, intakes of both total raw and total cooked vegetables considered separately were inversely related to BP in multivariate-adjusted models.
There is no difference among commonly consumed individual raw and cooked vegetable in reducing high blood pressure, particularly in cooked celery.
Taken altogether, celery, cooked or raw processed high amounts of n-butylphthalide (NBP) is considered a functional food for the prevention and treatment of high blood pressure with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Chemical constituents of fresh celery].[Article in Chinese] by Zhou K1, Wu B, Zhuang Y, Ding L, Liu Z, Qiu F(PubMed)
(2) Relations of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study by Chan Q1, Stamler J, Brown IJ, Daviglus ML, Van Horn L, Dyer AR, Oude Griep LM, Miura K, Ueshima H, Zhao L, Nicholson JK, Holmes E, Elliott P(PubMed)
(3) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(4) A Western dietary pattern is associated with higher blood pressure in Iranian adolescents by Hojhabrimanesh A1, Akhlaghi M1,2, Rahmani E2, Amanat S2, Atefi M2, Najafi M2, Hashemzadeh M2, Salehi S2, Faghih S. (PubMed)
Hypertension is the most common syndrome in the Western world caused by abnormally high blood pressure.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable.
The veggie can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.
There is no single cause of hypertension. Epidemiological studies suggested an unhealthy lifestyle such as a diet with high saturated and trans fat, red meat and processed food and low fruits and vegetables, smoking, overweight and obesity contributes to the onset of hypertension.
In the differentiate the correlation between the Western diet which had been promoted by the industries over the last many decades and the risk of hypertension, researchers indicated, the Western diet is one of major culprit associated to the rise of high blood pressure incidence in the adults of the Western world.
In other words, if you follow the Western diet, you will have chronic high blood pressure developed in some points during your lifetime. Luckily, if you make a change to a healthy diet, your risk of high blood pressure is reduced.
Dr. Hojhabrimanesh A, the lead scientists in the metabolic team at the Shiraz University of Medical Sciences in the classification of dietary risk of hypertension wrote, " three major dietary patterns were identified, among which only the Western pattern (abundant in soft drinks, sweets and desserts, salt, mayonnaise, tea and coffee, salty snacks, high-fat dairy products, French fries, and red or processed meats) had a significant association with BP".
And " After adjusting for potential confounders in the analysis of covariance models, multivariable adjusted means of the systolic and mean BP of subjects in the highest tertile of the Western pattern score were significantly higher than those in the lowest tertile".
With an aim to find a natural ingredient or whole food for the prevention and treatment of hypertension, researchers at the Mashhad University of Medical Sciences assessed the effects of different celery (Apium graveolens) seed extracts on blood pressure (BP).
In animal study, elected rats were induced hypertension by the injection of deoxycorticosterone acetate.
The hexanic, methanolic, and aqueous-ethanolic extracts were administered intraperitoneally to examine the tested animal antihypertensive effects on BP and heart rate (HR), compared to the spironolactone as a diuretic and positive control.
Application of all extracts decreased BP and increased the HR in hypertensive rats, with no effect on normotensive rats.
In volume analysis, administration of 300 mg/kg of hexanic, methanolic, and aqueous-ethanolic (20/80, v/v) extracts of the celery seed caused 38, 24, and 23 mmHg reduction in BP and 60, 25, and 27 beats per minute increase in the HR, respectively.
The effects of celery seed extracted were found to process high amounts of n-butylphthalide (NBP), which has been proven epidemiologically an antihypertensive constituent.
According to the HPLC analysis data revealed that the hexanic extract demonstrated the greatest effect in normalizing the high blood pressure due to the containing the 3.7 and 4 times NBP greater than that of the methanolic and aqueous-ethanolic extracts.
Dr. Moghadam MH, the lead scientist wrote in the final report, " celery seed extracts have antihypertensive properties, which appears to be attributable to the actions of its active hydrophobic constitutes such as NBP" and, "can be considered an antihypertensive agent in the chronic treatment of elevated BP".
Additionally, in the study to evaluate the inverse associations of overall vegetable intake to blood pressure (BP); whether such relations prevail for both raw and cooked vegetables, researchers launched a review of the report of the cross-sectional associations of vegetable intakes with BP for 2195 Americans ages 40-59 in the International Study of Macro/Micronutrients and Blood Pressure (INTERMAP).
According to the multiple linear regression assay, intakes of both total raw and total cooked vegetables considered separately were inversely related to BP in multivariate-adjusted models.
There is no difference among commonly consumed individual raw and cooked vegetable in reducing high blood pressure, particularly in cooked celery.
Taken altogether, celery, cooked or raw processed high amounts of n-butylphthalide (NBP) is considered a functional food for the prevention and treatment of high blood pressure with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) [Chemical constituents of fresh celery].[Article in Chinese] by Zhou K1, Wu B, Zhuang Y, Ding L, Liu Z, Qiu F(PubMed)
(2) Relations of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study by Chan Q1, Stamler J, Brown IJ, Daviglus ML, Van Horn L, Dyer AR, Oude Griep LM, Miura K, Ueshima H, Zhao L, Nicholson JK, Holmes E, Elliott P(PubMed)
(3) Antihypertensive effect of celery seed on rat blood pressure in chronic administration by Moghadam MH1, Imenshahidi M, Mohajeri SA.(PubMed)
(4) A Western dietary pattern is associated with higher blood pressure in Iranian adolescents by Hojhabrimanesh A1, Akhlaghi M1,2, Rahmani E2, Amanat S2, Atefi M2, Najafi M2, Hashemzadeh M2, Salehi S2, Faghih S. (PubMed)
Saturday, April 27, 2019
Herbal Artichoke Raises the Levels of "Good Bacteria" in the Gut
Gut microbiota is a complex community with over trillion microorganisms that live in our digestive tracts.
In healthy individuals, the ratio of good and bad microorganisms is balanced. In other words, healthy gut microbiota levels maintain the structure and function of the gastrointestinal tract.
In fact, balanced ratio of gut microbiota plays a critical role in the digestion of certain foods that the stomach and small intestine have not been able to digest, in the production vitamins, improvement of digestive functioning and modulation of the immune function.
Use of antibiotics has been found to damage the gut ecosystem, leading to certain chronic illness such as inflammatory bowel disease, obesity, cancer, and autism.
Further, the unbalanced ratio of gut microbiota functions also alters immune homeostasis, leading to the onset of autoimmune disorders which in turn can affect the development of not only intestinal but also systemic autoimmune diseases.
Compared to probiotics, the prebiotics is compound in food that induce the growth or activity of beneficial microorganisms in the gut.
In other definition, it is a special form of dietary fiber that acts as a fertilizer that promotes the growth of good bacteria in your gut.
In the gastrointestinal tract, prebiotics can alter the composition of organisms in the gut microbiome.
In other words, prebiotics raises the levels of healthy bacteria against bad bacteria.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on the finding a natural therapeutic which promotes probiotics examined the artichoke preparation on microbiota ecology and immune status.
The study included 48 piglets divided into 6 groups (n = 8), which received from day 10 of life probiotic-unsupplemented (PU) or probiotic-supplemented (PS, containing 0.5 g/kg diet and contained: Lactococcus lactis, Carnobacterium divergens, Lactobacillus casei, Lactobacillus plantarum, and Saccharomyces cerevisiae) diets.
The PU and PS diets were formulated without prebiotic addition (control) or with the addition of 2% of inulin from chicory root (IN) or 4% of dried Jerusalem artichoke tubers (DJA).
Feeding DJA diets showed to improve the balance of the gut microbiota by increasing the caecal valeric acid level, and decreasing the concentration of isoacids in the colon,
Furthermore, DJA diets also reduced β-glucosidase and β-glucuronidase activity induced gut toxicity in the middle colon and increased Bifidobacterium spp. populations in the proximal and distal colon.
These results suggested that DJA modified the microbiota ecology in the large intestine of young pigs to a greater extent as a prebiotic.
Taken altogether, artichoke may be considered a functional remedy as a prebiotic for the treatment of patients with unbalanced gut microbiota with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effects of inulin, dried Jerusalem artichoke tuber and a multispecies probiotic preparation on microbiota ecology and immune status of the large intestine in young pigs by Barszcz M1, Taciak M1, Skomiał J. (PubMed)
In healthy individuals, the ratio of good and bad microorganisms is balanced. In other words, healthy gut microbiota levels maintain the structure and function of the gastrointestinal tract.
In fact, balanced ratio of gut microbiota plays a critical role in the digestion of certain foods that the stomach and small intestine have not been able to digest, in the production vitamins, improvement of digestive functioning and modulation of the immune function.
Use of antibiotics has been found to damage the gut ecosystem, leading to certain chronic illness such as inflammatory bowel disease, obesity, cancer, and autism.
Further, the unbalanced ratio of gut microbiota functions also alters immune homeostasis, leading to the onset of autoimmune disorders which in turn can affect the development of not only intestinal but also systemic autoimmune diseases.
Compared to probiotics, the prebiotics is compound in food that induce the growth or activity of beneficial microorganisms in the gut.
In other definition, it is a special form of dietary fiber that acts as a fertilizer that promotes the growth of good bacteria in your gut.
In the gastrointestinal tract, prebiotics can alter the composition of organisms in the gut microbiome.
In other words, prebiotics raises the levels of healthy bacteria against bad bacteria.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
Researchers on the finding a natural therapeutic which promotes probiotics examined the artichoke preparation on microbiota ecology and immune status.
The study included 48 piglets divided into 6 groups (n = 8), which received from day 10 of life probiotic-unsupplemented (PU) or probiotic-supplemented (PS, containing 0.5 g/kg diet and contained: Lactococcus lactis, Carnobacterium divergens, Lactobacillus casei, Lactobacillus plantarum, and Saccharomyces cerevisiae) diets.
The PU and PS diets were formulated without prebiotic addition (control) or with the addition of 2% of inulin from chicory root (IN) or 4% of dried Jerusalem artichoke tubers (DJA).
Feeding DJA diets showed to improve the balance of the gut microbiota by increasing the caecal valeric acid level, and decreasing the concentration of isoacids in the colon,
Furthermore, DJA diets also reduced β-glucosidase and β-glucuronidase activity induced gut toxicity in the middle colon and increased Bifidobacterium spp. populations in the proximal and distal colon.
These results suggested that DJA modified the microbiota ecology in the large intestine of young pigs to a greater extent as a prebiotic.
Taken altogether, artichoke may be considered a functional remedy as a prebiotic for the treatment of patients with unbalanced gut microbiota with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effects of inulin, dried Jerusalem artichoke tuber and a multispecies probiotic preparation on microbiota ecology and immune status of the large intestine in young pigs by Barszcz M1, Taciak M1, Skomiał J. (PubMed)
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