The brain of mammals contains two major forms of cholinesterases: acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
Acetylcholinesterase (AChE) is the primary enzyme that hydrolyzes the neurotransmitter acetylcholine to choline and acetate.
Altered levels of ACh in the nervous system have been found to induce several neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington, depending on the affected areas.
Butyrylcholinesterase (BuChE) enzyme plays a minor role in regulating brain acetylcholine (ACh) levels.
A cholinergic neuron is a nerve cell which mainly is used by the neurotransmitter acetylcholine (ACh) to send its messages
Impairment of the cholinergic neuronal system in the brain was involved in the underlying event of cognitive impairment.
Cholinesterase inhibitors (ChEI) has been used for the treatment of Alzheimer's disease (AD).
Cramp Bark is an ornamental plant, genus Viburnum, belongings to the family Adoxaceae, native to Europe and Asia. It has been used in traditional and herbal medicine as anti-spasmodic, anti-inflammatory, nervine. hypotensive agent and to treat menstrual cramps and pain, afterbirth, postpartum pains, excessive blood loss in periods, bleeding associated with the menopause, etc.
On finding a potential herbal medicine for the prevention and treatment of associated with neurodegenerative diseases, researchers examined ethyl acetate, methanol, and water extracts prepared from the branches, leaves, and fruits of Viburnum opulus and Viburnum lantana along with salicin on acetylcholinesterase (AChE) inhibitory and antioxidant activities.
In vitro, according to the results from an enzyme-linked immunosorbent assay, the leaf methanol extract of V. opulus displayed a significantly high inhibitory effect against AChE at 50, 100, and 200 μL/mL concentrations of 57.63%, 87%, and 93%, respectively compared to other extracts.
In other words, the leaf methanol extract of V. opulus showed the highest protective activity against the disruption of neuron in the induction of neurodegenerative diseases linearly in a doses dependent-manner.
Compared to Viburnum opulus, the extracts of V. lantana exerted higher antioxidant activity.
Taken altogether, cramp bark(Viburnum opulus) leaves may be considered a functional acetylcholinesterase inhibitor herb medicine for the prevention and treatment of neurodegenerative diseases, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-acetylcholinesterase and antioxidant assets of the major components (salicin, amentoflavone, and chlorogenic acid) and the extracts of Viburnum opulus and Viburnum lantana and their total phenol and flavonoid contents by Erdogan-Orhan I1, Altun ML, Sever-Yilmaz B, Saltan G. (PubMed)
Monday, April 13, 2020
Sunday, April 12, 2020
Herbal Coltsfoot (Tussilago farfara), the Anti-Inflammation Herbal Remedy
Inflammation is a natural response in which the white blood cells in the first line of defense of the immune system try to destroy the harmful pathogens before they can enter the body to multiply inducing the acute phase of infection.
However, overproduction of pro-inflammatory cytokines in this phase can cause damage to the nearby healthy cells, leading abnormal production of collagen ratio in the initiation of scars forming.
Inflammation can be classified into 2 types
*Acute inflammation caused by trauma, microbial invasion, or noxious compounds, is a condition that starts rapidly, and becomes severe in a short time and lasts for a few days.
Most pathogens are stopped in the acute phase of infection, depending on the location and the size of the wound and tissue damage.
* Chronic inflammation is a slow, long-term inflammation, lasting for months to years caused by the inability of immunity to repair and overcome the damage or injury.
If the immune system can not kill off all invaded pathogens with a set of period of time, it will compromise, leading to the low-grade chronic inflammation with the persistent production of pro-inflammatory cytokines in the affected area.
Long-term low-grade inflammation ultimately leads to tissues and organ damage, inducing a number of chronic illnesses, including diabetes and cardiovascular disease.
Symptoms of low-grade chronic inflammation include body pain as in arthritis, constant fatigue and insomnia as in cancer, depression, anxiety, and mood disorders and gastrointestinal complications such as constipation, diarrhea, and acid reflux, unintended weight loss or gain depending on the infected tissues and organs.
According to statistics, chronic inflammatory diseases affects approximately 350 million people worldwide and nearly 43 million people in the United States or almost 20% of the population. The prevalence of the diseases is anticipated to increase persistently for the next 30 years, causing a financial burden on the economy and health care sector.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native in demagogical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of hypercholesterolemia, researchers examined the anti-inflammatory effect of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae).
According to the tested analysis, RAW264.7 cells treated by TSLshowed a significant activity to increase HO-1 protein expression associated with anti-inflammatory activity in a dose- and time-dependent manner without the induction of HO-1 mRNA expression.
In other words, TSL-mediated HO induction may be regulated at the translational level involved in the cellular response to stressors, growth cues, and differentiation through its anti-inflammatory properties.
Pro-inflammatory proteins such as nitric oxide (NO), tumor necrosis factor (TNF)-alpha, and prostaglandin E2 (PGE2) were also inhibited by the administration of TSL in lipopolysaccharide (LPS)-stimulated RAW264.7 cells.
Based on the findings, researchers said, "TSL may be an effective HO-1 inducer that has anti-inflammatory effects and a valuable compound for modulating inflammatory conditions.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of disease associated with inflammatory disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages by Hwangbo C1, Lee HS, Park J, Choe J, Lee JH. (PubMed)
(2) Chronic Inflammation by Roma Pahwa, and Ishwarlal Jialal. (NCBI)
However, overproduction of pro-inflammatory cytokines in this phase can cause damage to the nearby healthy cells, leading abnormal production of collagen ratio in the initiation of scars forming.
Inflammation can be classified into 2 types
*Acute inflammation caused by trauma, microbial invasion, or noxious compounds, is a condition that starts rapidly, and becomes severe in a short time and lasts for a few days.
Most pathogens are stopped in the acute phase of infection, depending on the location and the size of the wound and tissue damage.
* Chronic inflammation is a slow, long-term inflammation, lasting for months to years caused by the inability of immunity to repair and overcome the damage or injury.
If the immune system can not kill off all invaded pathogens with a set of period of time, it will compromise, leading to the low-grade chronic inflammation with the persistent production of pro-inflammatory cytokines in the affected area.
Long-term low-grade inflammation ultimately leads to tissues and organ damage, inducing a number of chronic illnesses, including diabetes and cardiovascular disease.
Symptoms of low-grade chronic inflammation include body pain as in arthritis, constant fatigue and insomnia as in cancer, depression, anxiety, and mood disorders and gastrointestinal complications such as constipation, diarrhea, and acid reflux, unintended weight loss or gain depending on the infected tissues and organs.
According to statistics, chronic inflammatory diseases affects approximately 350 million people worldwide and nearly 43 million people in the United States or almost 20% of the population. The prevalence of the diseases is anticipated to increase persistently for the next 30 years, causing a financial burden on the economy and health care sector.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native in demagogical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of hypercholesterolemia, researchers examined the anti-inflammatory effect of Tussilagone (TSL), isolated from the flower of buds of Tussilago farfara (Compositae).
According to the tested analysis, RAW264.7 cells treated by TSLshowed a significant activity to increase HO-1 protein expression associated with anti-inflammatory activity in a dose- and time-dependent manner without the induction of HO-1 mRNA expression.
In other words, TSL-mediated HO induction may be regulated at the translational level involved in the cellular response to stressors, growth cues, and differentiation through its anti-inflammatory properties.
Pro-inflammatory proteins such as nitric oxide (NO), tumor necrosis factor (TNF)-alpha, and prostaglandin E2 (PGE2) were also inhibited by the administration of TSL in lipopolysaccharide (LPS)-stimulated RAW264.7 cells.
Based on the findings, researchers said, "TSL may be an effective HO-1 inducer that has anti-inflammatory effects and a valuable compound for modulating inflammatory conditions.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of disease associated with inflammatory disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages by Hwangbo C1, Lee HS, Park J, Choe J, Lee JH. (PubMed)
(2) Chronic Inflammation by Roma Pahwa, and Ishwarlal Jialal. (NCBI)
Saturday, April 11, 2020
Herbal Ashwagandha Inhibits the Onset of Atherosclerosis in Diabetics
Atherosclerosis is a medical condition caused by plaques accumulated on the wall of the arteries, leading to narrowing the arteries in transporting oxygenated blood to the heart and other parts of the body.
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.
Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.
Untreated high blood cholesterol has been found to induce serious complications including carotid artery disease, coronary heart disease, peripheral artery disease, and stroke.
Dr, Yagi K, at the Institute of Applied Biochemistry in the analysis of the lipid peroxides and human diseases, said, "The lipid peroxidation (LPO) products are highly reactive and display marked biological effects, which, depending upon their concentration, cause selective alterations in cell signaling, protein and DNA damage, and cytotoxicity"
And. "Increased formation of lipid peroxides and aldehydes has been observed in atherosclerosis, ischemia-reperfusion, heart failure, Alzheimer’s disease, rheumatic arthritis, cancer, and other immunological disorders".
Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones and bile acid to aid digestion in the small intestine.
Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).
The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the prevention and treatment of atherosclerosis, researchers at the Meerut Institute of Engineering and Technology, Meerut, India, examined the anti hyperlipidemia and hyperglycemic of an aqueous extract of Withania coagulans (AWC).
According to the atherogenic index (AI) on streptozotocin (STZ)-induced diabetes.treated by AWC (1,000 mg/kg body weight, BW), AWC not reduced plasma glucose levels but also showed a strong activity against levels of glucose in diabetic rats.
Furthermore, AWC at sub-chronic dosing also exerted significantly decreasing plasma levels of CHL, HDL, and TG only in STZ-induced diabetic rats.
Moreover, in STZ-induced diabetic animals compared to normal rats, repeated administration of AWC also significantly decreased AI and prevented weight loss.
Based on the findings, researchers said, "AWC showed anti-hyperlipidemic activity in diabetic rats and was suggested to be a suitable candidate for the treatment of atherosclerosis associated with diabetes".
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of atherosclerosis in diabetics, pending to the result of larger sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-hyperlipidemic activity of Withania coagulans in streptozotocin-induced diabetes: A potent anti-atherosclerotic agent by Saxena B. (PubMed)
Depending on the blood obstruction, atherosclerosis can induce different types of heart disease and stroke.
Plaque is the make of cholesterols, calcium, and other toxic substances, including cadmium.
Hyperlipidemia is a medical condition characterized by abnormally high levels of cholesterol in the bloodstream.
Overexpression of cholesterol levels in the bloodstream has been linked to plaques accumulation on the arterial walls, a major cause of some forms of heart disease and stroke.
Untreated high blood cholesterol has been found to induce serious complications including carotid artery disease, coronary heart disease, peripheral artery disease, and stroke.
Dr, Yagi K, at the Institute of Applied Biochemistry in the analysis of the lipid peroxides and human diseases, said, "The lipid peroxidation (LPO) products are highly reactive and display marked biological effects, which, depending upon their concentration, cause selective alterations in cell signaling, protein and DNA damage, and cytotoxicity"
And. "Increased formation of lipid peroxides and aldehydes has been observed in atherosclerosis, ischemia-reperfusion, heart failure, Alzheimer’s disease, rheumatic arthritis, cancer, and other immunological disorders".
Cholesterol is the type of fat produced by the liver or from fat intake playing a critical role in the building of strong cell walls, production of vitamin D and steroid hormones and bile acid to aid digestion in the small intestine.
Cholesterol produced by the liver in a healthy individual is returned to the liver by high-density lipoprotein (HDL).
The healthy ratio of HDL/LDL cholesterol is any numbers that are less than 1/4.
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the prevention and treatment of atherosclerosis, researchers at the Meerut Institute of Engineering and Technology, Meerut, India, examined the anti hyperlipidemia and hyperglycemic of an aqueous extract of Withania coagulans (AWC).
According to the atherogenic index (AI) on streptozotocin (STZ)-induced diabetes.treated by AWC (1,000 mg/kg body weight, BW), AWC not reduced plasma glucose levels but also showed a strong activity against levels of glucose in diabetic rats.
Furthermore, AWC at sub-chronic dosing also exerted significantly decreasing plasma levels of CHL, HDL, and TG only in STZ-induced diabetic rats.
Moreover, in STZ-induced diabetic animals compared to normal rats, repeated administration of AWC also significantly decreased AI and prevented weight loss.
Based on the findings, researchers said, "AWC showed anti-hyperlipidemic activity in diabetic rats and was suggested to be a suitable candidate for the treatment of atherosclerosis associated with diabetes".
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of atherosclerosis in diabetics, pending to the result of larger sample size and multicenter study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Anti-hyperlipidemic activity of Withania coagulans in streptozotocin-induced diabetes: A potent anti-atherosclerotic agent by Saxena B. (PubMed)
Friday, April 10, 2020
Cranberry, the Anti Urinary Tract Infection Healthy Food
Infection is an inflammatory condition caused by a microbial invasion on body tissues
Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.
The most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.
Urinary tract infection (UTIs) mostly occurred in women is an infection that affects the bladder and urethra caused mostly by bacterial strains Escherichia coli (E. coli), commonly found in the gastrointestinal (GI) tract.
UTIs have been found to limit the function of the bladder and induce kidney infection.
The most common symptoms of urinary infection are a persistent urge to urinate, urinary burning sensation, cloudy urine, and smelly urine.
In severe cases, patients may also experience symptoms of blood in the urine and bladder and pelvic pain.
The most common risk factors of urinary tract infection are gender, females are more like to have UTI compared to males, sexual activity, use of birth control, and menopausal women.
Some researchers suggested that sexual intercourse may increase the risk of symptomatic urinary tract infection in postmenopausal women.
Dr. Elya E. Moore, the lead scientist in the joint study lead by the University of Washington School of Public Health and Community Medicine wrote, ".., as with younger women, sexual intercourse is strongly associated with UTI in post-menopausal women, supporting a common mechanism for infection among women of widely varying ages".
And, " This finding emphasizes the clinical importance of inquiring about recent sexual intercourse when treating post-menopausal women for symptomatic urinary tract infections".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of urinary infection, researchers examined the effect of cranberry anti urinary tract infections (UTIs) activity.
Based on the analysis, cranberry consumption showed a significant effect on decreasing UTI related symptoms by suppressing inflammatory associated with the immunologic response to pathogenic invasion by eradicating the bacteria.
Furthermore, injection of cranberry against UTIs was also found to prevent the development of infections only in populations at lower risk for contracting UTIs compared to low effective in a higher risk population.
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of UTIs, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry for Urinary Tract Infection: From Bench to Bedside by Nabavi SF, Sureda A, Daglia M, Izadi M, Nabavi SM. (PubMed)
(2) Current clinical status on the preventive effects of cranberry consumption against urinary tract infections by Vasileiou I1, Katsargyris A, Theocharis S, Giaginis C. (PubMed)
(3) Sexual Intercourse and Risk of Symptomatic Urinary Tract Infection in Post-Menopausal Women by Elya E. Moore, Ph.D. Stephen E. Hawes, Ph.D.,1 Delia Scholes, Ph.D.,1,3 Edward J. Boyko, MD, MPH,1,4,5 James P. Hughes, Ph.D.,6 and Stephan D. Fihn, MD, MPH. (PubMed)
Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has been found to make them resistant to antibiotics.
The most common symptoms of bacterial infection include redness and heat, swelling, fever, pain at the site of infection.
Urinary tract infection (UTIs) mostly occurred in women is an infection that affects the bladder and urethra caused mostly by bacterial strains Escherichia coli (E. coli), commonly found in the gastrointestinal (GI) tract.
UTIs have been found to limit the function of the bladder and induce kidney infection.
The most common symptoms of urinary infection are a persistent urge to urinate, urinary burning sensation, cloudy urine, and smelly urine.
In severe cases, patients may also experience symptoms of blood in the urine and bladder and pelvic pain.
The most common risk factors of urinary tract infection are gender, females are more like to have UTI compared to males, sexual activity, use of birth control, and menopausal women.
Some researchers suggested that sexual intercourse may increase the risk of symptomatic urinary tract infection in postmenopausal women.
Dr. Elya E. Moore, the lead scientist in the joint study lead by the University of Washington School of Public Health and Community Medicine wrote, ".., as with younger women, sexual intercourse is strongly associated with UTI in post-menopausal women, supporting a common mechanism for infection among women of widely varying ages".
And, " This finding emphasizes the clinical importance of inquiring about recent sexual intercourse when treating post-menopausal women for symptomatic urinary tract infections".
Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.
On finding a potential compound for the treatment of urinary infection, researchers examined the effect of cranberry anti urinary tract infections (UTIs) activity.
Based on the analysis, cranberry consumption showed a significant effect on decreasing UTI related symptoms by suppressing inflammatory associated with the immunologic response to pathogenic invasion by eradicating the bacteria.
Furthermore, injection of cranberry against UTIs was also found to prevent the development of infections only in populations at lower risk for contracting UTIs compared to low effective in a higher risk population.
Taken altogether, cranberry may be considered a remedy for the prevention and treatment of UTIs, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cranberry for Urinary Tract Infection: From Bench to Bedside by Nabavi SF, Sureda A, Daglia M, Izadi M, Nabavi SM. (PubMed)
(2) Current clinical status on the preventive effects of cranberry consumption against urinary tract infections by Vasileiou I1, Katsargyris A, Theocharis S, Giaginis C. (PubMed)
(3) Sexual Intercourse and Risk of Symptomatic Urinary Tract Infection in Post-Menopausal Women by Elya E. Moore, Ph.D. Stephen E. Hawes, Ph.D.,1 Delia Scholes, Ph.D.,1,3 Edward J. Boyko, MD, MPH,1,4,5 James P. Hughes, Ph.D.,6 and Stephan D. Fihn, MD, MPH. (PubMed)
Thursday, April 9, 2020
Herbal Chamomile Extracts That Normalize the (Over and Under Active) Function of Immune System
Chamomile (Matricaria chamomilla), in a recent study conducted by some renowned institutions, restored the resistance against lethal infection with the predominately granulocyte-dependant Candida albicans in immunosuppressed mice.
The immune system is the set of cells comprised of the body's defense system against diseases.
In normal immunity, active immunity may also be artificially acquired active immunity caused by the injection of the vaccine, a substance that contains antigen and passive immunity is an auto-response of immune system against infection through the production of antigen.
Immunity can also be passive and active, Dr. David Baxter, in the article of "Active and passive immunity, vaccine types, excipients and licensing" wrote, "Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long-lasting—even lifelong" and " Passive immunity refers to the process of providing IgG antibodies to protect against infection; it gives immediate, but short-lived protection—several weeks to 3 or 4 months at most. Passive immunity is usually classified as natural or acquired"(3).
However, an abnormal immune response such as overactive and underactive may cause a weakened immune system or autoimmune diseases.
The common characteristic of overactive immunity is the immune system that attacks healthy tissues, thus provoking inflammation, as well as tissue and organ damage. Truly, there are an estimated 80 autoimmune diaereses, that affect 14–22 million Americans, or 5%–8% of the population, and their prevalence is on the rise, according to the US National Institutes of Health (NIH)(4).
Underactive immunity can be a primary immune deficiency or acquired immune deficiency. People with weakened immunity, regardless of the cause are at constant danger of infections from bacteria, viruses, and fungi.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae,
The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
In the study to examine the immunomodulatory effect of a group of the medicinal plant including Silene (Silene Nocturna), Black seed (Nigella sativa) and Chamomile (Matricaria chamomilla) growing in Egypt in Balb/c mice, researchers found that intraperitoneal injection chamomile methanolic extract was found to enhance immunity through the increased total white blood cells count(1).
In comparison to other plant extracts, chamomile extracts also increased bone marrow cellularity significantly(1).
Furthermore, spleen weight of chamomile treated groups was significantly increased. increased weight of spleen is an indication of improved immune activity as spleen plays an important role in the modulation of the immune system and in the maintenance of peripheral tolerance via the clearance of circulating apoptotic cells, the differentiation and activation of T and B cells and production of antibodies(5)
In groups induced immunosuppressed with cyclophosphamide, group pretreated with the chamomile extracts inhibit Candida significantly through restored their resistance against lethal infection with the predominately granulocyte-dependant Candida albicans(1).
Dr. Ghonime M, the lead author said, These results confirm the immunomodulatory activity of Silene, Black seed, and Chamomile extracts and may have therapeutical implications in the prophylactic treatment of opportunistic infections and as supportive treatment in oncogenic cases".
According to the Russian State Medical University, Moscow, heteropolysaccharides, a class of sugars, found in Matricaria chamomilla L. showed to normalize the development of the immune response upon air cooling.
These results are attributed to chamomile heteropolysaccharides effects in initiated immunostimulating properties of heavy erythrocytes (macrocytes), the group of enlargement of red blood cells, activated of immunoregulation of cells of peripheral blood and increased the sensitivity of effector cells to helper signals.
Dr. Ghonime M, the lead author, said, "immunomodulatory activity,.....Chamomile extracts may have therapeutical implications in the prophylactic treatment of opportunistic infections and as supportive treatment in oncogenic cases".
There is no doubt that chamomile and its chemical ingredients have expressed a strong immunomodulatory activity in the protection of our body against various diseases, but the intake of large quantities should be taken with care to avoid toxicity.
However, further data collection on large example size and multi-centers studies performed with human consumption of the chamomile extracts during the course of the disease will be necessary to complete the picture of chamomile immunomodulatory possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of immunomodulatory effect of three herbal plants growing in Egypt by Ghonime M1, Eldomany R, Abdelaziz A, Soliman H.(PubMed)
(2) [The immunomodulating activity of the heteropolysaccharides from German chamomile(Matricaria chamomilla) during air and immersion cooling].[Article in Russian] by Uteshev BS1, Laskova IL, Afanas'ev VA.(PubMed)
(3) Active and passive immunity, vaccine types, excipients and licensing by David Baxter(Oxford Academic)
(4) When the immune system goes on the attack by Vicki Brower(PMC)
(5) Liver-spleen axis: Intersection between immunity, infections and metabolism by Giovanni Tarantino, Antonella Scalera, and Carmine Finelli(PMC)
The immune system is the set of cells comprised of the body's defense system against diseases.
In normal immunity, active immunity may also be artificially acquired active immunity caused by the injection of the vaccine, a substance that contains antigen and passive immunity is an auto-response of immune system against infection through the production of antigen.
Immunity can also be passive and active, Dr. David Baxter, in the article of "Active and passive immunity, vaccine types, excipients and licensing" wrote, "Active immunity refers to the process of exposing the body to an antigen to generate an adaptive immune response: the response takes days/weeks to develop but may be long-lasting—even lifelong" and " Passive immunity refers to the process of providing IgG antibodies to protect against infection; it gives immediate, but short-lived protection—several weeks to 3 or 4 months at most. Passive immunity is usually classified as natural or acquired"(3).
However, an abnormal immune response such as overactive and underactive may cause a weakened immune system or autoimmune diseases.
The common characteristic of overactive immunity is the immune system that attacks healthy tissues, thus provoking inflammation, as well as tissue and organ damage. Truly, there are an estimated 80 autoimmune diaereses, that affect 14–22 million Americans, or 5%–8% of the population, and their prevalence is on the rise, according to the US National Institutes of Health (NIH)(4).
Underactive immunity can be a primary immune deficiency or acquired immune deficiency. People with weakened immunity, regardless of the cause are at constant danger of infections from bacteria, viruses, and fungi.
Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae,
The herb has been used in traditional medicine as antispasmodic and anti-inflammatory constituents and to treat menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.
In the study to examine the immunomodulatory effect of a group of the medicinal plant including Silene (Silene Nocturna), Black seed (Nigella sativa) and Chamomile (Matricaria chamomilla) growing in Egypt in Balb/c mice, researchers found that intraperitoneal injection chamomile methanolic extract was found to enhance immunity through the increased total white blood cells count(1).
In comparison to other plant extracts, chamomile extracts also increased bone marrow cellularity significantly(1).
Furthermore, spleen weight of chamomile treated groups was significantly increased. increased weight of spleen is an indication of improved immune activity as spleen plays an important role in the modulation of the immune system and in the maintenance of peripheral tolerance via the clearance of circulating apoptotic cells, the differentiation and activation of T and B cells and production of antibodies(5)
In groups induced immunosuppressed with cyclophosphamide, group pretreated with the chamomile extracts inhibit Candida significantly through restored their resistance against lethal infection with the predominately granulocyte-dependant Candida albicans(1).
Dr. Ghonime M, the lead author said, These results confirm the immunomodulatory activity of Silene, Black seed, and Chamomile extracts and may have therapeutical implications in the prophylactic treatment of opportunistic infections and as supportive treatment in oncogenic cases".
According to the Russian State Medical University, Moscow, heteropolysaccharides, a class of sugars, found in Matricaria chamomilla L. showed to normalize the development of the immune response upon air cooling.
These results are attributed to chamomile heteropolysaccharides effects in initiated immunostimulating properties of heavy erythrocytes (macrocytes), the group of enlargement of red blood cells, activated of immunoregulation of cells of peripheral blood and increased the sensitivity of effector cells to helper signals.
Dr. Ghonime M, the lead author, said, "immunomodulatory activity,.....Chamomile extracts may have therapeutical implications in the prophylactic treatment of opportunistic infections and as supportive treatment in oncogenic cases".
There is no doubt that chamomile and its chemical ingredients have expressed a strong immunomodulatory activity in the protection of our body against various diseases, but the intake of large quantities should be taken with care to avoid toxicity.
However, further data collection on large example size and multi-centers studies performed with human consumption of the chamomile extracts during the course of the disease will be necessary to complete the picture of chamomile immunomodulatory possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Evaluation of immunomodulatory effect of three herbal plants growing in Egypt by Ghonime M1, Eldomany R, Abdelaziz A, Soliman H.(PubMed)
(2) [The immunomodulating activity of the heteropolysaccharides from German chamomile(Matricaria chamomilla) during air and immersion cooling].[Article in Russian] by Uteshev BS1, Laskova IL, Afanas'ev VA.(PubMed)
(3) Active and passive immunity, vaccine types, excipients and licensing by David Baxter(Oxford Academic)
(4) When the immune system goes on the attack by Vicki Brower(PMC)
(5) Liver-spleen axis: Intersection between immunity, infections and metabolism by Giovanni Tarantino, Antonella Scalera, and Carmine Finelli(PMC)
Wednesday, April 8, 2020
Herbal Chaste Tree Berry Normalizes Menstrual Cycle and Enhanced Pregnancy in Women with Oligomenorrhea
A renowned study suggested that Chaste tree berry has a potential effect in enhancing pregnancy in women with the abnormal menstrual cycle.
Fertility is a natural process to ensure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at its peak in a suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at its minimum state and we produce less offspring when the environment is hostile including fewer foods around, war, epidemic.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
In a total of 37 women with oligomenorrhea and 30 women with amenorrhea received 50 drops of Phyto Hypophyson L, a preparation from Chaste tree berry or placebo 3 times a day over 3 months or 3 cycles, the preparation not only normalized the menstrual cycle of women with oligomenorrhea but also significantly improved the chance of pregnancy, compared placebo group.
Dr. Bergmann J, the lead author said, " The baby take-home rate during the therapy and 6 months after the end of the therapy showed a ratio of 18.7 /6.4%)".
The effectiveness of the preparation in an enhanced rate of pregnancy with remarkable outcome maybe
due to the increase of progesterone during the luteal phase compared to the oligomenorrhea placebo group, with only very few undesirable side effects.
In another study with the same group of women, researchers found that treatment of preparation to women with sterility and oligomenorrhea can induce pregnancy over a period of 3-6 months with an attractive rate.
Promisingly, in a randomized double-blind study to test the effect of Vitex agnus castus preparation (Strotan capsules) vs. placebo, involved 52 women with luteal phase defects due to latent hyperprolactinaemia, women who are taking the daily dose of one capsule (20 mg) Vitexagnus cactus preparation reserved the elevated pituitary prolactin and normalized deficits in luteal phase length and increased luteal phase progesterone synthesis. comparable to placebo, after three months of therapy.
Dr. Milewicz A, the lead researcher said, "Side effects were not seen, two women treated with the Vitex agnus castus preparation got pregnant. The tested preparation is thought to be an efficient medication in the treatment of luteal phase defects due to latent hyperprolactinemia".
Taking together, Chaste tree berry may have a pharmaceutical value in promoting pregnancy in women with sterility and oligomenorrhea, but large doses should be taken with care against toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women by Westphal LM1, Polan ML, Trant AS.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latenthyperprolactinemia. Results of a randomized placebo-controlled double-blind study].
[Article in German]by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) [The efficacy of the complex medication Phyto-Hypophyson L in female, hormone-related sterility. A randomized, placebo-controlled clinical double-blind study].[Article in German]by Bergmann J1, Luft B, Boehmann S, Runnebaum B, Gerhard I.(PubMed)
Fertility is a natural process to ensure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at its peak in a suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at its minimum state and we produce less offspring when the environment is hostile including fewer foods around, war, epidemic.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
In a total of 37 women with oligomenorrhea and 30 women with amenorrhea received 50 drops of Phyto Hypophyson L, a preparation from Chaste tree berry or placebo 3 times a day over 3 months or 3 cycles, the preparation not only normalized the menstrual cycle of women with oligomenorrhea but also significantly improved the chance of pregnancy, compared placebo group.
Dr. Bergmann J, the lead author said, " The baby take-home rate during the therapy and 6 months after the end of the therapy showed a ratio of 18.7 /6.4%)".
The effectiveness of the preparation in an enhanced rate of pregnancy with remarkable outcome maybe
due to the increase of progesterone during the luteal phase compared to the oligomenorrhea placebo group, with only very few undesirable side effects.
In another study with the same group of women, researchers found that treatment of preparation to women with sterility and oligomenorrhea can induce pregnancy over a period of 3-6 months with an attractive rate.
Promisingly, in a randomized double-blind study to test the effect of Vitex agnus castus preparation (Strotan capsules) vs. placebo, involved 52 women with luteal phase defects due to latent hyperprolactinaemia, women who are taking the daily dose of one capsule (20 mg) Vitexagnus cactus preparation reserved the elevated pituitary prolactin and normalized deficits in luteal phase length and increased luteal phase progesterone synthesis. comparable to placebo, after three months of therapy.
Dr. Milewicz A, the lead researcher said, "Side effects were not seen, two women treated with the Vitex agnus castus preparation got pregnant. The tested preparation is thought to be an efficient medication in the treatment of luteal phase defects due to latent hyperprolactinemia".
Taking together, Chaste tree berry may have a pharmaceutical value in promoting pregnancy in women with sterility and oligomenorrhea, but large doses should be taken with care against toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Double-blind, placebo-controlled study of Fertilityblend: a nutritional supplement for improving fertility in women by Westphal LM1, Polan ML, Trant AS.(PubMed)
(2) [Vitex agnus castus extract in the treatment of luteal phase defects due to latenthyperprolactinemia. Results of a randomized placebo-controlled double-blind study].
[Article in German]by Milewicz A1, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.(PubMed)
(3) [The efficacy of the complex medication Phyto-Hypophyson L in female, hormone-related sterility. A randomized, placebo-controlled clinical double-blind study].[Article in German]by Bergmann J1, Luft B, Boehmann S, Runnebaum B, Gerhard I.(PubMed)
Tuesday, April 7, 2020
Turmeric, the Potential Spice that Detoxes Your Lung Against Toxicity
Lung toxicity or pulmonary toxicity refers to the toxicity induced by the side effects of the lung in patients under chemotherapy or radiotherapy.
The most common drugs associated with lung toxicity used for the treatment of cancer include Arsenic trioxide (Trisenox®) Bleomycin (Blenoxane®)1 Idarubicin (Idamycin®).
However, lung toxicity is also caused by inhaling chemical compounds, the most famous (infamous) example is pulmonary toxicity due to asbestos. air pollution and airborne particulate matter produced by car traffic, overland traffic (trucks), industrial production facilities, and cigarette smoking.
Symptoms of lung damage or toxicity are a shortage of breath, breathlessness during exercise, fatigue dry cough Shortness of breath, particularly the symptoms that worsen when lying on your back breath.
Acute pulmonary toxicity, the damage to the lungs that resolves with a short period of time by addressing the cause.
Conventionally, most common treatments of lung toxicity are the use of
* Corticosteroids to decrease inflammation and relieve the cough and pain
*Narcotics to reduce pain medications and promote breathing center
* Oxygen therapy to increase oxygen in the blood and prevent shortness of breath.
In severe cases, patients may be sent to the hospital for pulmonary (lung) rehabilitation.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of lung toxicity scientists evaluated the protective effects of curcumin on lipid peroxidation and antioxidants status in bronchoalveolar lavage fluid (BALF) and bronchoalveolar lavage (BAL) of a nicotine-treated animal model.
Wistar rats selected to the study were induced lung toxicity by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (5 days a week, for 22 weeks) and following by administration of curcumin (80 mg/kg body weight) given simultaneously by intragastric intubation for 22 weeks.
Before injecting curcumin, injection of nicotine rats showed the increased biochemical marker enzymes, lipid peroxides in BALF and BAL accompanied by a significant decrease in the levels of antioxidants in the lung.
Following the treatment of curcumin, infected rats showed a significantly lowered the biochemical marker enzymes, lipid peroxidation and enhanced the antioxidant status.
Based on the results, researchers said, "The results of the present study suggest that curcumin exerts its protective effect against nicotine-induced lung toxicity by modulating the biochemical marker enzymes, lipid peroxidation and augmenting antioxidant defense system".
In order to reveal more information about turmeric detoxed activity, researchers examined the protective role of curcumin and a synthetic analog of curcumin (BDMC-A) on nicotine-induced oxidative stress.
Male albino rats of Wistar strain selected to the study induced lung toxicity by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (five days a week, for 22 weeks) and followed by the treatment of curcuminoids given simultaneously by intragastric intubation for 22 weeks.
Nicotine-treated groups before injection of curcumin showed increased oxidative stress, as evidenced by lipid peroxidation indices.
Injection of curcumin and BDMC-A not only restored the antioxidant status which was decreased in the nicotine-treated group.
Based on the findings, researchers said, "The present study suggests that BDMC-A exerts its protective effect by modulating the extent of lipid peroxidation and augmenting the antioxidant defense system".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of lung toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in Wistar rats by Kalpana C1, Menon VP. (PubMed)
(2) Comparative effects of curcumin and its synthetic analogue on tissue lipid peroxidation and antioxidant status during nicotine-induced toxicity by Kalpana C1, Sudheer AR, Rajasekharan KN, Menon VP. (PubMed)
The most common drugs associated with lung toxicity used for the treatment of cancer include Arsenic trioxide (Trisenox®) Bleomycin (Blenoxane®)1 Idarubicin (Idamycin®).
However, lung toxicity is also caused by inhaling chemical compounds, the most famous (infamous) example is pulmonary toxicity due to asbestos. air pollution and airborne particulate matter produced by car traffic, overland traffic (trucks), industrial production facilities, and cigarette smoking.
Symptoms of lung damage or toxicity are a shortage of breath, breathlessness during exercise, fatigue dry cough Shortness of breath, particularly the symptoms that worsen when lying on your back breath.
Acute pulmonary toxicity, the damage to the lungs that resolves with a short period of time by addressing the cause.
Conventionally, most common treatments of lung toxicity are the use of
* Corticosteroids to decrease inflammation and relieve the cough and pain
*Narcotics to reduce pain medications and promote breathing center
* Oxygen therapy to increase oxygen in the blood and prevent shortness of breath.
In severe cases, patients may be sent to the hospital for pulmonary (lung) rehabilitation.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of lung toxicity scientists evaluated the protective effects of curcumin on lipid peroxidation and antioxidants status in bronchoalveolar lavage fluid (BALF) and bronchoalveolar lavage (BAL) of a nicotine-treated animal model.
Wistar rats selected to the study were induced lung toxicity by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (5 days a week, for 22 weeks) and following by administration of curcumin (80 mg/kg body weight) given simultaneously by intragastric intubation for 22 weeks.
Before injecting curcumin, injection of nicotine rats showed the increased biochemical marker enzymes, lipid peroxides in BALF and BAL accompanied by a significant decrease in the levels of antioxidants in the lung.
Following the treatment of curcumin, infected rats showed a significantly lowered the biochemical marker enzymes, lipid peroxidation and enhanced the antioxidant status.
Based on the results, researchers said, "The results of the present study suggest that curcumin exerts its protective effect against nicotine-induced lung toxicity by modulating the biochemical marker enzymes, lipid peroxidation and augmenting antioxidant defense system".
In order to reveal more information about turmeric detoxed activity, researchers examined the protective role of curcumin and a synthetic analog of curcumin (BDMC-A) on nicotine-induced oxidative stress.
Male albino rats of Wistar strain selected to the study induced lung toxicity by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (five days a week, for 22 weeks) and followed by the treatment of curcuminoids given simultaneously by intragastric intubation for 22 weeks.
Nicotine-treated groups before injection of curcumin showed increased oxidative stress, as evidenced by lipid peroxidation indices.
Injection of curcumin and BDMC-A not only restored the antioxidant status which was decreased in the nicotine-treated group.
Based on the findings, researchers said, "The present study suggests that BDMC-A exerts its protective effect by modulating the extent of lipid peroxidation and augmenting the antioxidant defense system".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of lung toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in Wistar rats by Kalpana C1, Menon VP. (PubMed)
(2) Comparative effects of curcumin and its synthetic analogue on tissue lipid peroxidation and antioxidant status during nicotine-induced toxicity by Kalpana C1, Sudheer AR, Rajasekharan KN, Menon VP. (PubMed)
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