Topical use of essential oil extracted from cinnamon may be the next generation whole herb medicine for prevention and treatment of menstrual pain and heavy menstrual bleeding.
The results of the investigation were reported by several respectable institutes and published on the data bases of numbers online medical literature, including PubMed.
According to the Eulji University, in the study of compared the effect of aromatherapy massage and acetaminophen on menstrual pain in Korean high school girls. cinnamon treatment group showed a significantly higher reduction of menstrual pain than in the acetaminophen group.
Acetaminophen or APAP is a over-counter and popular conventional medicine used to treat pain and fever with numbers of intolerant adverse effects.
In a randomized, double-blind trial, out of 114, group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h significantly reduced the severity and duration of pain during menstruation and menstrual bleeding.
In primary dysmenorrhea, cinnamon expressed significantly over the reduction of pain, menstrual bleeding, nausea, and vomiting with primary dysmenorrhea without side effects.
Dr. Marzouk TM., the lead author at the Mansoura University said, " ... aromatherapy abdominal massage once daily for seven days prior to menstruation using the essential oils (cinnamon....) is effective in alleviating menstrual pain, its duration and excessive menstrual bleeding...." and "Aromatherapy can be provided as a nonpharmacological pain relief measure and as a part of nursing care given to girls suffering from dysmenorrhea, or excessive menstrual bleeding".
Further study of the effect of cinnamon extract on symptoms of dysmenorrhea and contractility in some smooth muscles, Dr. Alotaibi M. suggested, cinnamon may be used to alleviate menstrual pain associated with dysmenorrhoea or prevent unwanted uterine activity in early pregnancy.
However, intake of cinnamon should be taken with care as toxicity was found in the case of overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study by Hur MH1, Lee MS, Seong KY, Lee MK.(PubMed)
(2) Comparative effect of cinnamon and Ibuprofen for treatment of primary dysmenorrhea: a randomized double-blind clinical trial by Jaafarpour M1, Hatefi M2, Khani A3, Khajavikhan J4.(PubMed)
(3) The effect of cinnamon on menstrual bleeding and systemic symptoms with primary dysmenorrhea by Jaafarpour M1, Hatefi M2, Najafi F3, Khajavikhan J4, Khani A3.(PubMed)
(4) The effect of aromatherapy abdominal massage on alleviating menstrual pain in nursing students: a prospective randomized cross-over study by Marzouk TM1, El-Nemer AM, Baraka HN.(PubMed)
(5) The effect of cinnamon extract on isolated rat uterine strips by Alotaibi M1.(PubMed)
Please note that all articles written by Kyle. J. Norton are for information and education only, please consult with your doctor or related field specialist before applying. http://diseases-researches.blogspot.ca/
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Natural Medicine for Fatty Liver And Obesity Reversal
Thursday, April 30, 2020
Wednesday, April 29, 2020
Herbal Bilberry, the Natural Treatment for Varicose Veins with No Side Effects
Varicose veins are the medical condition in which the superficial veins have become enlarged and twisted.
The condition has been found to induce bleeding or superficial thrombophlebitis if left untreated.
The most common causes of varicose veins are found just under the skin in the legs, leading to the symptoms of fullness and pain in the affected location accompanied by symptoms of achy or heavy feeling in the legs. The pain is also worsened after a long time of sitting or standing for a long time and skin discoloration around the area.
Some patients with painful varicose veins also experience symptoms of burning, throbbing, muscle cramping, and swelling in the lower legs and itching.
Out of many risk factors associated with the onset of varicose veins, aging due to wear and tear on the valves in the veins that help regulate blood flow may be one of the most common risk factors.
Dr. Caggiati A in the study of age-related variations of varicose veins, wrote, "Varicose SVs were more frequent in the older group (62%) than in younger one (39%) owing to a higher prevalence of limbs with combined saphenous veins (SVs) and Stributaries of the SVs (STVs) varicosities (respectively, 59% and 37%)".
And, "varicose disease may progressively extend in an antegrade fashion, spreading from the STVs to the SVs".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a natural ingredient for the treatment of varicose veins and chronic venous insufficiency (CVI), researchers compared the efficacy of Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) against the therapeutic compressions.
The study included 1,051 patients who completed the registry. During the experiment, there are no safety or tolerability problems observed.
Mirtoselect (bilberry) showed a significant effect on skin flux but to a lesser extent compared to those of Venoruton, Pycnogenol, and the combination VE-PY.
The edema score was decreased more effectively with the combination and with Pycnogenol compared to the other treatment group including the Mirtoselect (bilberry).
According to the improvement in symptoms score, Pycnogenol and compression showed a larger decrease in oxidative stress compared to the Pycnogenol, Venoruton, Mirtoselect (bilberry), and with the VE-PY combination.
However, the efficacy of Pycnogenol and the combination are competitive with stockings that do not have the same tolerability in warmer climates compared to other groups.
The findings suggested that the tested compounds processed anti chronic venous insufficiency (CVI) and varicose veins properties.
Taken altogether, Mirtoselect (bilberry) may be considered a functioning remedy for the treatment of varicose veins with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings by Belcaro G1, Dugall M1, Luzzi R1, Corsi M1, Ledda A1, Ricci A1, Pellegrini L1, Cesarone MR1, Hosoi M1, Errichi BM1, Cornelli U1, Cotellese R1, Agus G1, Feragalli B. (PubMed)
(2) Age-related variations of varicose veins anatomy by Caggiati A1, Rosi C, Heyn R, Franceschini M, Acconcia MC. (PubMed)
The condition has been found to induce bleeding or superficial thrombophlebitis if left untreated.
The most common causes of varicose veins are found just under the skin in the legs, leading to the symptoms of fullness and pain in the affected location accompanied by symptoms of achy or heavy feeling in the legs. The pain is also worsened after a long time of sitting or standing for a long time and skin discoloration around the area.
Some patients with painful varicose veins also experience symptoms of burning, throbbing, muscle cramping, and swelling in the lower legs and itching.
Out of many risk factors associated with the onset of varicose veins, aging due to wear and tear on the valves in the veins that help regulate blood flow may be one of the most common risk factors.
Dr. Caggiati A in the study of age-related variations of varicose veins, wrote, "Varicose SVs were more frequent in the older group (62%) than in younger one (39%) owing to a higher prevalence of limbs with combined saphenous veins (SVs) and Stributaries of the SVs (STVs) varicosities (respectively, 59% and 37%)".
And, "varicose disease may progressively extend in an antegrade fashion, spreading from the STVs to the SVs".
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe.
The plant has been used as herbs in traditional medicine for the treatment of acute and chronic diarrhea, gastritis, gastric ulcer, and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease, and psoriasis, diabetes, etc.
With an aim to find a natural ingredient for the treatment of varicose veins and chronic venous insufficiency (CVI), researchers compared the efficacy of Pycnogenol, venoruton, troxerutin, the complex diosmin-hesperidin, Antistax, Mirtoselect (bilberry), escin, and the combination Venoruton-Pycnogenol (VE-PY) against the therapeutic compressions.
The study included 1,051 patients who completed the registry. During the experiment, there are no safety or tolerability problems observed.
Mirtoselect (bilberry) showed a significant effect on skin flux but to a lesser extent compared to those of Venoruton, Pycnogenol, and the combination VE-PY.
The edema score was decreased more effectively with the combination and with Pycnogenol compared to the other treatment group including the Mirtoselect (bilberry).
According to the improvement in symptoms score, Pycnogenol and compression showed a larger decrease in oxidative stress compared to the Pycnogenol, Venoruton, Mirtoselect (bilberry), and with the VE-PY combination.
However, the efficacy of Pycnogenol and the combination are competitive with stockings that do not have the same tolerability in warmer climates compared to other groups.
The findings suggested that the tested compounds processed anti chronic venous insufficiency (CVI) and varicose veins properties.
Taken altogether, Mirtoselect (bilberry) may be considered a functioning remedy for the treatment of varicose veins with no side effects, pending to the validation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Management of Varicose Veins and Chronic Venous Insufficiency in a Comparative Registry with Nine Venoactive Products in Comparison with Stockings by Belcaro G1, Dugall M1, Luzzi R1, Corsi M1, Ledda A1, Ricci A1, Pellegrini L1, Cesarone MR1, Hosoi M1, Errichi BM1, Cornelli U1, Cotellese R1, Agus G1, Feragalli B. (PubMed)
(2) Age-related variations of varicose veins anatomy by Caggiati A1, Rosi C, Heyn R, Franceschini M, Acconcia MC. (PubMed)
Tuesday, April 28, 2020
Herbal Chaste Tree Berry Anti Estrogenic Activity
Chaste tree berry(Vitex agnus-castus), is found to process anti-estrogenic property in binding the estrogen receptors for a balance between the activities of estrogen receptor ERα or ERβ.
The herb is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Anti estrogenic effects are an act of binding the estrogen receptor(ERα ) and/ERβ in inhibiting the excessive levels of estrogen circulating in the body.
According to the University of Alabama in Huntsville, in the study of the potential effect of estrogen mimics or anti-estrogens in phytochemicals of popular dietary herbal supplements, researchers found that almost all herbal supplements containing phytochemical components showed a capability in binding to the human estrogen receptor and exhibit selective estrogen receptor modulation, including chaste tree berry.
Casticin, a flavonoid isolated from Vitex rotundifolia, significantly expressed anti estrogenic effect in reduced the prolactin release stimulated by E2 in induced inhibition of ERα mRNA expression in a concentration-dependent manner, through its anti estrogenic effect.
In a hyperprolactinemia (MIHP) induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats, rat treated with casticin (10, 20, and 40 mg/kg, ip, for 7 d) reduced serum prolactin levels by 33.9%, 54.3%, and 64.7% and at(1 and 10 micromol/L) inhibited E2-induced pituitary cell proliferation by 27.7% and 42.1%, respectively through reduced levels of 17β-Estradiol (E2) significantly.
More importantly, oral administration of casticin, a flavonoid isolated from Vitex rotundifolia displayed an anti-estrogenic activity in decrease excessive levels of 17β-Estradiol (E2) significantly
Taking together, Chaste tree berry processes strong estrogenic and anti-estrogenic effects in binding estrogen receptor sites to preserve the balancing of hormone expression of estrogen through ER alpha and ERBeta inhibition and exhibition.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements by Powers CN1, Setzer WN1.(PubMed)
(2) Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro by YE Q1, ZHANG QY, ZHENG CJ, WANG Y, QIN LP.(PubMed)
The herb is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Anti estrogenic effects are an act of binding the estrogen receptor(ERα ) and/ERβ in inhibiting the excessive levels of estrogen circulating in the body.
According to the University of Alabama in Huntsville, in the study of the potential effect of estrogen mimics or anti-estrogens in phytochemicals of popular dietary herbal supplements, researchers found that almost all herbal supplements containing phytochemical components showed a capability in binding to the human estrogen receptor and exhibit selective estrogen receptor modulation, including chaste tree berry.
Casticin, a flavonoid isolated from Vitex rotundifolia, significantly expressed anti estrogenic effect in reduced the prolactin release stimulated by E2 in induced inhibition of ERα mRNA expression in a concentration-dependent manner, through its anti estrogenic effect.
In a hyperprolactinemia (MIHP) induced by administration of metoclopramide dihydrochloride (50 mg/kg, tid, ip, for 10 d) in SD rats, rat treated with casticin (10, 20, and 40 mg/kg, ip, for 7 d) reduced serum prolactin levels by 33.9%, 54.3%, and 64.7% and at(1 and 10 micromol/L) inhibited E2-induced pituitary cell proliferation by 27.7% and 42.1%, respectively through reduced levels of 17β-Estradiol (E2) significantly.
More importantly, oral administration of casticin, a flavonoid isolated from Vitex rotundifolia displayed an anti-estrogenic activity in decrease excessive levels of 17β-Estradiol (E2) significantly
Taking together, Chaste tree berry processes strong estrogenic and anti-estrogenic effects in binding estrogen receptor sites to preserve the balancing of hormone expression of estrogen through ER alpha and ERBeta inhibition and exhibition.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements by Powers CN1, Setzer WN1.(PubMed)
(2) Casticin, a flavonoid isolated from Vitex rotundifolia, inhibits prolactin release in vivo and in vitro by YE Q1, ZHANG QY, ZHENG CJ, WANG Y, QIN LP.(PubMed)
Monday, April 27, 2020
Dandelion (Taraxacum officinale) Processes a Strong Antifungal Activity
Fungal infection is a common disease caused by the overgrowth of fungus.
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
Yeasts, molds, and mushrooms are types of fungi. The tiny microorganisms have cells with nuclear.
Most common fungal infections start from the lungs or the skin. Long-term use of antibiotics and people with the weakened immune system is susceptible to fungal infection, epidemiologically.
However, some researchers suggested that common risk factors for fungal infection also include pregnancy, diabetes mellitus, oral contraceptives, and inadequate therapy.
People with weakened immune systems such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes includes jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,......, and burning sensation.
In women, signs of a yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........, and unusual vaginal discharge.
In men, signs of a yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of fungal infectious diseases,
scientists examined the antifungal effects of novel peptide named ToAMP4 isolated from Taraxacum officinale Wigg. flowers by a combination of acetic acid extraction and different types of chromatography.
According to the tested differentiation of the biological activity of ToAMP4 produced in a prokaryotic expression system as a fusion protein with thioredoxin, the peptide ToAMP4 displayed broad-spectrum antifungal activity against phytopathogens.
Moreover, the two ToAMP4 also exerted significantly mediated inhibition properties, on the tested fungus
In other words, ToAMP4 processed anti-fungal infection depending on the types of fungus.
Taken altogether, dandelion may be considered a remedy for the prevention and treatment of fungal infection, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A novel cysteine-rich antifungal peptide ToAMP4 from Taraxacum officinale Wigg. flowers by Astafieva AA1, Rogozhin EA, Andreev YA, Odintsova TI, Kozlov SA, Grishin EV, Egorov TA. (PubMed)
In other words, the immune system that protects the body against microorganisms has been overwhelming by the overgrowth of fungus.
Yeasts, molds, and mushrooms are types of fungi. The tiny microorganisms have cells with nuclear.
Most common fungal infections start from the lungs or the skin. Long-term use of antibiotics and people with the weakened immune system is susceptible to fungal infection, epidemiologically.
However, some researchers suggested that common risk factors for fungal infection also include pregnancy, diabetes mellitus, oral contraceptives, and inadequate therapy.
People with weakened immune systems such as cancer treatment, frequent use of antibiotics are associated to increase the risk of fungal infection.
Patients with diabetes are also more prone to fungal infections. Fungal infection associated with diabetes includes jock itch, athlete's foot,..... and ringworm.
Depending on the locations of infection, patients may experience symptoms of common peeling, cracking, scaling redness, blisters Itching,......, and burning sensation.
In women, signs of a yeast infection may include itching and swelling around the vagina. burning sensations or pain during urination or intercourse,........, and unusual vaginal discharge.
In men, signs of a yeast infection may include burning and itching around the head of the penis,
redness, and swelling, pain during urination or sex,..... small, rash-like bumps.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the prevention and treatment of fungal infectious diseases,
scientists examined the antifungal effects of novel peptide named ToAMP4 isolated from Taraxacum officinale Wigg. flowers by a combination of acetic acid extraction and different types of chromatography.
According to the tested differentiation of the biological activity of ToAMP4 produced in a prokaryotic expression system as a fusion protein with thioredoxin, the peptide ToAMP4 displayed broad-spectrum antifungal activity against phytopathogens.
Moreover, the two ToAMP4 also exerted significantly mediated inhibition properties, on the tested fungus
In other words, ToAMP4 processed anti-fungal infection depending on the types of fungus.
Taken altogether, dandelion may be considered a remedy for the prevention and treatment of fungal infection, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A novel cysteine-rich antifungal peptide ToAMP4 from Taraxacum officinale Wigg. flowers by Astafieva AA1, Rogozhin EA, Andreev YA, Odintsova TI, Kozlov SA, Grishin EV, Egorov TA. (PubMed)
Sunday, April 26, 2020
Cinnamon, The Whole Herbal Medicine for Osteopenic Disease
Recent study suggested that cinnamon may be effective in prevented and treatment of osteopenic disease by inhibiting protein in transferred information of cytokine production involved cell survival.
Cinnamon is a spice derived from the inner bark of the tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The osteopenic disease is the early stage of osteoporosis involved the deletion of bone density in comparison to the healthy person.
According to the Keio University, cinnamon suppressed the osteoclastogenesis, protected bone density against erosion, interleukin-4 (IL-4), an anti-inflammatory cytokine, involved the production of white blood cell in inhibition of osteoclast differentiation through the expression of T cell of the immune system
Dr. Tsuji-Naito K. in the study of Interleukin-4 suggested that Cinnamomum zeylanicum (C. zeylanicum) exhibited strong inhibitory effects on osteoclastogenesis,......involved the regulation of white blood cells in osteoclastogenesis.
In a comprehensive systematic review of vitro and in-vivo, using databases from PubMed, Web of Science, SciVerse Scopus published before 31st December 2012, cinnamon has shown to express inhibitory effects on osteoclastogenesis with minimal toxic and adverse effects.
The effectiveness of cinnamon in reduced risk of Osteopenic diseases in inducing bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis may result in inhibition of inflammatory cytokines expression in the immune system. Use of cinnamon should be taken with care, as the herbal medicine has induced toxicity if overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1 by Takatsuna H1, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.(PubMed)
(2) Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation by Tsuji-Naito K1.(PubMed)
(3) Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review by Ranasinghe P1, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P.(PubMed)
Cinnamon is a spice derived from the inner bark of the tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, used in herbal and traditional medicine as anti-fungal and bacteria level, to improve reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The osteopenic disease is the early stage of osteoporosis involved the deletion of bone density in comparison to the healthy person.
According to the Keio University, cinnamon suppressed the osteoclastogenesis, protected bone density against erosion, interleukin-4 (IL-4), an anti-inflammatory cytokine, involved the production of white blood cell in inhibition of osteoclast differentiation through the expression of T cell of the immune system
Dr. Tsuji-Naito K. in the study of Interleukin-4 suggested that Cinnamomum zeylanicum (C. zeylanicum) exhibited strong inhibitory effects on osteoclastogenesis,......involved the regulation of white blood cells in osteoclastogenesis.
In a comprehensive systematic review of vitro and in-vivo, using databases from PubMed, Web of Science, SciVerse Scopus published before 31st December 2012, cinnamon has shown to express inhibitory effects on osteoclastogenesis with minimal toxic and adverse effects.
The effectiveness of cinnamon in reduced risk of Osteopenic diseases in inducing bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis may result in inhibition of inflammatory cytokines expression in the immune system. Use of cinnamon should be taken with care, as the herbal medicine has induced toxicity if overdoses.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1 by Takatsuna H1, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.(PubMed)
(2) Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation by Tsuji-Naito K1.(PubMed)
(3) Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review by Ranasinghe P1, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P.(PubMed)
Saturday, April 25, 2020
Herbal Butterbur, the Anti Asthma Functional Remedy
Scientists may have found a medicinal plant for the prevention and treatment of asthma with no side effects, according to studies.
Asthma is a chronic inflammatory disease, affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.
Most signs and symptoms of asthma are triggered by exposure to various irritants and substances such as allergens.
Researchers do not know why some people are prone to the substances that trigger the symptoms of asthma while others do not, even process the same health conditions in the same family.
According to the American Lung Association, there are many risk factors can trigger the onset of the diseases, including respiratory problems during infancy and childhood such as wheezing, children who experience viral respiratory infections, children who have an allergic condition, such as atopic dermatitis (eczema) or allergic rhinitis (hay fever), can also develop asthma.
The most preventable risk factors that cause the onset of adults asthma are smoking and obesity. Dr. Chen Y and colleagues at the University of Ottawa in the investigation of the risk asthma in among female Canadians wrote, "The prevalence of asthma was 10.4% for males and 11.2% for females aged 12-24 years. Among the subjects aged 25 years or more, the prevalence varied from 4.1% to 5.8% for men and from 4.9% to 6.4% for women".
And, "Female smokers demonstrated a 1.7-fold increase in the prevalence of asthma compared with female nonsmokers" and " the prevalence of asthma increased with increasing body mass index in females".
The results strongly suggested that if you are female and you don't want to have asthma, you must lose weight and quit smoking.
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.
It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.
With an aim to find a natural remedy for the treatment of asthma with no side effects, researchers at the examine the phytoceuticals (non-nutritional but beneficial plant chemicals) used as a pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD).
Recently, herbal butterbur has been found to benefit and improve treatments for lung disease, particularly in that of airway inflammatory disease, including asthma and chronic obstructive pulmonary disease (COPD.
Ovalbumin (OVA) immunized BALB/c mice selected to the experiment were given intranasally together with antigen challenge in the murine model of allergic airway disease (asthma)
The analysis of the inflammatory and immune parameters in the lung suggested FET treated mice exerted a significant effect in inhibiting the allergic response.
Furthermore, PET also inhibited airway hyperresponsiveness (AHR) and eosinophil recruitment into the bronchoalveolar lavage (BAL) fluid upon allergen challenge observed by a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs but had no effect in the saline control mice.
According to the reading eosinophilic activation marker, PET at a concentration of 100 microg strongly lowered the levels of serum eosinophil peroxidase (EPO).
These results suggested inflammation, eosinophil recruitment, and mucus hyperproduction are significantly decreased in the lung with the administration of 100 microg PET.
Moreover, at the concentration of 30 microg PET, researchers found that airway hyperresponsiveness (AHR) and inflammation of treated mice associated with the production of inflammatory cytokines reduced (IL-4, IL-5) and RANTES production involved the mediation of acute and chronic inflammation are strongly reduced without affecting the expression of IgE and eotaxin serum levels.
Where Eotaxin is a small protein produced in the lungs of asthmatic patients.
The finding indicated PET inhibited the expression of asthma through decreasing the airway hyperresponsiveness, airway inflammation, eosinophil recruitment, and mucus hyperproduction of the asthmatic mice, in a dose-dependent manner.
Taken altogether, herbal butterbur may be considered a natural remedy for the prevention and combined with conventional medicine for the treatment of asthma and COPD with no side effects, pending to the confirmation of the large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.
Grandhi S, Donnelly LE, Rogers DF.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A1, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
(3) Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994-1995 by Chen Y1, Dales R, Krewski D, Breithaupt K. (PubMed)
Asthma is a chronic inflammatory disease, affecting the airway of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.
Most signs and symptoms of asthma are triggered by exposure to various irritants and substances such as allergens.
Researchers do not know why some people are prone to the substances that trigger the symptoms of asthma while others do not, even process the same health conditions in the same family.
According to the American Lung Association, there are many risk factors can trigger the onset of the diseases, including respiratory problems during infancy and childhood such as wheezing, children who experience viral respiratory infections, children who have an allergic condition, such as atopic dermatitis (eczema) or allergic rhinitis (hay fever), can also develop asthma.
The most preventable risk factors that cause the onset of adults asthma are smoking and obesity. Dr. Chen Y and colleagues at the University of Ottawa in the investigation of the risk asthma in among female Canadians wrote, "The prevalence of asthma was 10.4% for males and 11.2% for females aged 12-24 years. Among the subjects aged 25 years or more, the prevalence varied from 4.1% to 5.8% for men and from 4.9% to 6.4% for women".
And, "Female smokers demonstrated a 1.7-fold increase in the prevalence of asthma compared with female nonsmokers" and " the prevalence of asthma increased with increasing body mass index in females".
The results strongly suggested that if you are female and you don't want to have asthma, you must lose weight and quit smoking.
Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.
It has been used in herbal medicine used as a pain reliever in the digestive system, including stomach, bile ducts, and duodenum, etc.
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin, and iso-S-petasin, etc.
With an aim to find a natural remedy for the treatment of asthma with no side effects, researchers at the examine the phytoceuticals (non-nutritional but beneficial plant chemicals) used as a pharmacotherapy for asthma and chronic obstructive pulmonary disease (COPD).
Recently, herbal butterbur has been found to benefit and improve treatments for lung disease, particularly in that of airway inflammatory disease, including asthma and chronic obstructive pulmonary disease (COPD.
Ovalbumin (OVA) immunized BALB/c mice selected to the experiment were given intranasally together with antigen challenge in the murine model of allergic airway disease (asthma)
The analysis of the inflammatory and immune parameters in the lung suggested FET treated mice exerted a significant effect in inhibiting the allergic response.
Furthermore, PET also inhibited airway hyperresponsiveness (AHR) and eosinophil recruitment into the bronchoalveolar lavage (BAL) fluid upon allergen challenge observed by a medical procedure in which a bronchoscope is passed through the mouth or nose into the lungs but had no effect in the saline control mice.
According to the reading eosinophilic activation marker, PET at a concentration of 100 microg strongly lowered the levels of serum eosinophil peroxidase (EPO).
These results suggested inflammation, eosinophil recruitment, and mucus hyperproduction are significantly decreased in the lung with the administration of 100 microg PET.
Moreover, at the concentration of 30 microg PET, researchers found that airway hyperresponsiveness (AHR) and inflammation of treated mice associated with the production of inflammatory cytokines reduced (IL-4, IL-5) and RANTES production involved the mediation of acute and chronic inflammation are strongly reduced without affecting the expression of IgE and eotaxin serum levels.
Where Eotaxin is a small protein produced in the lungs of asthmatic patients.
The finding indicated PET inhibited the expression of asthma through decreasing the airway hyperresponsiveness, airway inflammation, eosinophil recruitment, and mucus hyperproduction of the asthmatic mice, in a dose-dependent manner.
Taken altogether, herbal butterbur may be considered a natural remedy for the prevention and combined with conventional medicine for the treatment of asthma and COPD with no side effects, pending to the confirmation of the large sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Phytoceuticals: the new 'physic garden' for asthma and chronic obstructive pulmonary disease.
Grandhi S, Donnelly LE, Rogers DF.(PubMed)
(2) Petasites extract Ze 339 (PET) inhibits allergen-induced Th2 responses, airway inflammation and airway hyperreactivity in mice by Brattström A1, Schapowal A, Maillet I, Schnyder B, Ryffel B, Moser R.(PubMed)
(3) Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994-1995 by Chen Y1, Dales R, Krewski D, Breithaupt K. (PubMed)
Friday, April 24, 2020
Herbal Ashwagandha Improves Fertility in Men
Infertility is a reproductive disease characterized by the failure to produce a pregnancy after 12 regular unprotected sexual intercourse, including pregnancy that can not be carried to term.
Infertility is very common in the US, approximately 10% of women or 6.1 million, ages 15-44 have difficulty getting pregnant or staying pregnant, according to the Centers for Disease Control and Prevention (CDC).
Believe it or not, only a very small number of such groups are seeking help from the professionals.
In men, age, pesticide and chemical exposure, drug use, radiation, pollution, cigarette or marijuana smoke, heavy alcohol consumption may be some risk factors for the onset of infertility.
In fact, some unfertilized women and men sometimes ago are fertile. However, here are some reasons that have found to increase the risk of infertility in the Western world, including
* Persuade a personal career, before having children.
*Try to be financial stability before having children.
* Too young to be a parent, raising a child needs efforts, time and money.
* Enjoy the couple childless years before committing.
Some researchers suggested that the widespread obesity in North America may be the major factor correlated to the increased infertile rate over the past few decades.
Dr. Nicole O. Palmer the lead scientist in the concern of obesity in the risk of men infertility, wrote, "Obesity has detrimental influences on all systems, including reproductive health. The prevalence of obesity in infertile women is high, and it is well known that there is an association between obesity and infertility".
And, "Recent data has shown that male obesity also impairs offspring metabolic and reproductive health suggesting that paternal health cues are transmitted to the next generation with the mediator mostly likely occurring via the sperm.".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of infertility, researchers examined beneficial effects induced by oral intake of the Withania sominifera (Ashwagandha) on semen quality of infertile men.
Based on the tested analysis, oral intake of Ashwagandha roots only improved sperm count and motility, and regulate reproductive hormone levels. but also inhibited the lipid peroxidation associated with the risk of infertility.
In a molecular perspective, oral intake of Ashwagandha roots inhibited the mitigation of oxidative stress and pathways involved in hormonal imbalance by enhancing the interaction of different endocrine glands to improve male fertility.
More precisely, Ashwagandha roots improved men's fertility by mitigating risk factor-that cause the onset of men's infertility.
In stress-induced male infertility on selected normozoospermic but infertile individuals (N = 60) that: divided into normozoospermic heavy smokers (N = 20), normozoospermic under psychological stress (N = 20) and normozoospermic with infertility of unknown etiology (N = 20).
Compared to Normozoospermic fertile men (N = 60), root powder of W. somnifera at a rate of 5 g/day for 3 months showed a strong effect in the treatment of stress-related infertility by improving the level of anti-oxidants and overall semen quality.
Root powder of W. somnifera treatment also resulted in pregnancy in the partners of 14% of the patients.
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of male infertility, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Role of Withania somnifera (Ashwagandha) in the management of male infertility by Sengupta P1, Agarwal A2, Pogrebetskaya M3, Roychoudhury S4, Durairajanayagam D5, Henkel R. (PubMed)
(2) Withania somnifera Improves Semen Quality in Stress-Related Male Fertility by Mahdi AA1, Shukla KK, Ahmad MK, Rajender S, Shankhwar SN, Singh V, Dalela D. (PubMed)
(3) Impact of obesity on male fertility, sperm function and molecular composition by Nicole O. Palmer, Hassan W. Bakos, Tod Fullston, and Michelle Lane. (PMC)
Infertility is very common in the US, approximately 10% of women or 6.1 million, ages 15-44 have difficulty getting pregnant or staying pregnant, according to the Centers for Disease Control and Prevention (CDC).
Believe it or not, only a very small number of such groups are seeking help from the professionals.
In men, age, pesticide and chemical exposure, drug use, radiation, pollution, cigarette or marijuana smoke, heavy alcohol consumption may be some risk factors for the onset of infertility.
In fact, some unfertilized women and men sometimes ago are fertile. However, here are some reasons that have found to increase the risk of infertility in the Western world, including
* Persuade a personal career, before having children.
*Try to be financial stability before having children.
* Too young to be a parent, raising a child needs efforts, time and money.
* Enjoy the couple childless years before committing.
Some researchers suggested that the widespread obesity in North America may be the major factor correlated to the increased infertile rate over the past few decades.
Dr. Nicole O. Palmer the lead scientist in the concern of obesity in the risk of men infertility, wrote, "Obesity has detrimental influences on all systems, including reproductive health. The prevalence of obesity in infertile women is high, and it is well known that there is an association between obesity and infertility".
And, "Recent data has shown that male obesity also impairs offspring metabolic and reproductive health suggesting that paternal health cues are transmitted to the next generation with the mediator mostly likely occurring via the sperm.".
Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.
The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.
On finding a potent compound for the treatment of infertility, researchers examined beneficial effects induced by oral intake of the Withania sominifera (Ashwagandha) on semen quality of infertile men.
Based on the tested analysis, oral intake of Ashwagandha roots only improved sperm count and motility, and regulate reproductive hormone levels. but also inhibited the lipid peroxidation associated with the risk of infertility.
In a molecular perspective, oral intake of Ashwagandha roots inhibited the mitigation of oxidative stress and pathways involved in hormonal imbalance by enhancing the interaction of different endocrine glands to improve male fertility.
More precisely, Ashwagandha roots improved men's fertility by mitigating risk factor-that cause the onset of men's infertility.
In stress-induced male infertility on selected normozoospermic but infertile individuals (N = 60) that: divided into normozoospermic heavy smokers (N = 20), normozoospermic under psychological stress (N = 20) and normozoospermic with infertility of unknown etiology (N = 20).
Compared to Normozoospermic fertile men (N = 60), root powder of W. somnifera at a rate of 5 g/day for 3 months showed a strong effect in the treatment of stress-related infertility by improving the level of anti-oxidants and overall semen quality.
Root powder of W. somnifera treatment also resulted in pregnancy in the partners of 14% of the patients.
Taken altogether, Ashwagandha may be considered a functional herb for the treatment of male infertility, pending to the result of larger sample size and multicenter study
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Role of Withania somnifera (Ashwagandha) in the management of male infertility by Sengupta P1, Agarwal A2, Pogrebetskaya M3, Roychoudhury S4, Durairajanayagam D5, Henkel R. (PubMed)
(2) Withania somnifera Improves Semen Quality in Stress-Related Male Fertility by Mahdi AA1, Shukla KK, Ahmad MK, Rajender S, Shankhwar SN, Singh V, Dalela D. (PubMed)
(3) Impact of obesity on male fertility, sperm function and molecular composition by Nicole O. Palmer, Hassan W. Bakos, Tod Fullston, and Michelle Lane. (PMC)
Thursday, April 23, 2020
Dandelion (Taraxacum officinale), the Best Antioxidant Functional Herbal Medicine
Antioxidants are stable atoms that inhibit oxidation caused by free radicals.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.
Believe it or not, free radicals also play a critical role in maintaining a certain body function. The Journal of Physiology showed that free radicals act as signal substances that cause the heart to beat with the correct force.
In healthy individuals, antioxidant enzymes produced by the liver are good enough to balance the free radical produced by the cell metabolism and external sources such as the air we breathe and the food we eat.
However, in people with a weakened immune system such as infants, children, and the elderly, dietary sources from supplements, fruits and vegetables may be needed.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world.
The herbal medicine has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined in vitro and in vivo the antioxidant effects of 70% ethanol-water (v/v) leaf and root extracts of T. officinale (TOL and TOR, respectively).
The study included organ homogenate samples from Nω-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, treated by leaf extracts of TOL (500 mg/kg/day) and TOR (500 mg/kg/day) for 21 days.
Based on the results from the experiment, the antioxidant contents of ) polyphenol (4.35 ± 0.15 compared to 1.14 ± 0.01) and flavonoid (23.17 ± 0.14 compared to 3 ± 0.05) of TOL are significantly higher compared to TOR.
TOL exerted a significantly higher free radical scavenging activity (EC50 0.37 compared to 1.34 mg/mL) and total antioxidant capacities (82.56% compared to 61.54% ABTS, and 156 ± 5.28 compared to 40 ± 0.31 FRAP) compared to TOR.
Furthermore, both extracts inhibited the oxidative stress marker MDA levels and increased the total antioxidant capacity (TAC) without inducing toxicity with LD50 > 5000 mg/kg).
Collectively, T. officinale leaf extract possesses significant anti-oxidant effects that conferred significant in vivo antioxidant protection against free radical-mediated oxidative stress in L-NAME-induced hypertensive rats.
Taken altogether, dandelion may be considered a remedy for enhancing the antioxidant capacity against oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In Vitro and In Vivo Antioxidant Properties of Taraxacum officinale in Nω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats by Aremu OO1, Oyedeji AO2, Oyedeji OO3, Nkeh-Chungag BN4, Rusike CRS, (PubMed)
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.
Believe it or not, free radicals also play a critical role in maintaining a certain body function. The Journal of Physiology showed that free radicals act as signal substances that cause the heart to beat with the correct force.
In healthy individuals, antioxidant enzymes produced by the liver are good enough to balance the free radical produced by the cell metabolism and external sources such as the air we breathe and the food we eat.
However, in people with a weakened immune system such as infants, children, and the elderly, dietary sources from supplements, fruits and vegetables may be needed.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world.
The herbal medicine has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined in vitro and in vivo the antioxidant effects of 70% ethanol-water (v/v) leaf and root extracts of T. officinale (TOL and TOR, respectively).
The study included organ homogenate samples from Nω-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, treated by leaf extracts of TOL (500 mg/kg/day) and TOR (500 mg/kg/day) for 21 days.
Based on the results from the experiment, the antioxidant contents of ) polyphenol (4.35 ± 0.15 compared to 1.14 ± 0.01) and flavonoid (23.17 ± 0.14 compared to 3 ± 0.05) of TOL are significantly higher compared to TOR.
TOL exerted a significantly higher free radical scavenging activity (EC50 0.37 compared to 1.34 mg/mL) and total antioxidant capacities (82.56% compared to 61.54% ABTS, and 156 ± 5.28 compared to 40 ± 0.31 FRAP) compared to TOR.
Furthermore, both extracts inhibited the oxidative stress marker MDA levels and increased the total antioxidant capacity (TAC) without inducing toxicity with LD50 > 5000 mg/kg).
Collectively, T. officinale leaf extract possesses significant anti-oxidant effects that conferred significant in vivo antioxidant protection against free radical-mediated oxidative stress in L-NAME-induced hypertensive rats.
Taken altogether, dandelion may be considered a remedy for enhancing the antioxidant capacity against oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In Vitro and In Vivo Antioxidant Properties of Taraxacum officinale in Nω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats by Aremu OO1, Oyedeji AO2, Oyedeji OO3, Nkeh-Chungag BN4, Rusike CRS, (PubMed)
Wednesday, April 22, 2020
Herbal Cleaver(Galium aparine), inhibits the Melanoma Cell Metastasis in Vitro
Skin melanoma is a skin cancer characterized by the alternation of the pigment-containing cells known as melanocytes. However, in rare cases, melanoma can also occur in the mouth, intestines, or eye.
Most cases of melanoma start in melanocytes on skin before spreading to the nearby tissue. In the advanced stage, the cancer cells can also travel a distance away from the originated site to infect other tissues and organs, leading to secondary metastasis, through the circulation of blood and fluids.
The most common sites of melanoma metastasis are the lung and breast.
The most common symptoms are visible by examing the change of skin, including the sores that can not heal itself, redness or swelling, persistent itching, tenderness and pain and particular, change of skin color, and bleeding off of a mole compared to the normal moles.
The 4 most common types of skin melanoma include
* Superficial spreading melanoma, the type of cancer has a tendency to spread grow outward and spread across the surface of the skin, accounted for 70% of all melanoma skin cancer.
* Nodular melanoma normally grows down into the skin and has a tendency to spread more quickly than other types of melanoma skin cancer.
* Lentigo malignant melanoma, most common in the older population, making up approximately 15% of all melanoma skin cancer.
* Acral lentiginous melanoma, most common in people with darker skin. Cancer first moves outward before spreading deeper into the skin.
According to the statistics provided by the American Cancer Society, in 2019, approximately, 96,480 new melanomas will be diagnosed (about 57,220 in men and 39,260 in women) in the US. The condition also causes the death of 4,740 men and 2,490 women.
Believe it or not. most cases of melanoma are found in older adults. The average age diagnosed with melanoma is 63.
Cleaver is a herbaceous annual plant, genus Galium, belonging to the family Rubiaceae, native to North America and Eurasia. The herb has been used over thousands of years in herbal and traditional medicine as mild diuretic and blood and lymphatic cleanser and to treat psoriasis, skin conditions, glands, tonsillitis, bladder infections, prevent small kidney stone, etc.
On finding a potential compound for the treatment of skin diseases, researchers investigated the Gallic acid (GA) found in herbal Cleaver in the inhibition of the growth of human cancer cells in vitro and in vivo.
GA decreases the expression of MMPs MMPs mRNA levels in A375.S2 human melanoma cells in stimulating the cancer cell metastasis.
Furthermore, GA processed antimetastatic potential by decreasing the invasiveness of cancer cells.
Moreover, this action of GA was involved in the Ras, p-ERK signaling pathways with function to communicate a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell to induce the inhibition of MMP-2 associated with cancer spreading in A375.S2 human melanoma cells.
Based on the findings, researchers said, " These data, therefore, provide evidence for the role of GA as a potential cancer chemotherapeutic agent, which can markedly inhibit the invasive capacity of melanoma cells".
o
Taken altogether, Comfrey may be considered a remedy to inhibit cancer call spreading, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras by Lo C1, Lai TY, Yang JS, Yang JH, Ma YS, Weng SW, Lin HY, Chen HY, Lin JG, Chung JG. (PubMed)
Most cases of melanoma start in melanocytes on skin before spreading to the nearby tissue. In the advanced stage, the cancer cells can also travel a distance away from the originated site to infect other tissues and organs, leading to secondary metastasis, through the circulation of blood and fluids.
The most common sites of melanoma metastasis are the lung and breast.
The most common symptoms are visible by examing the change of skin, including the sores that can not heal itself, redness or swelling, persistent itching, tenderness and pain and particular, change of skin color, and bleeding off of a mole compared to the normal moles.
The 4 most common types of skin melanoma include
* Superficial spreading melanoma, the type of cancer has a tendency to spread grow outward and spread across the surface of the skin, accounted for 70% of all melanoma skin cancer.
* Nodular melanoma normally grows down into the skin and has a tendency to spread more quickly than other types of melanoma skin cancer.
* Lentigo malignant melanoma, most common in the older population, making up approximately 15% of all melanoma skin cancer.
* Acral lentiginous melanoma, most common in people with darker skin. Cancer first moves outward before spreading deeper into the skin.
According to the statistics provided by the American Cancer Society, in 2019, approximately, 96,480 new melanomas will be diagnosed (about 57,220 in men and 39,260 in women) in the US. The condition also causes the death of 4,740 men and 2,490 women.
Believe it or not. most cases of melanoma are found in older adults. The average age diagnosed with melanoma is 63.
Cleaver is a herbaceous annual plant, genus Galium, belonging to the family Rubiaceae, native to North America and Eurasia. The herb has been used over thousands of years in herbal and traditional medicine as mild diuretic and blood and lymphatic cleanser and to treat psoriasis, skin conditions, glands, tonsillitis, bladder infections, prevent small kidney stone, etc.
On finding a potential compound for the treatment of skin diseases, researchers investigated the Gallic acid (GA) found in herbal Cleaver in the inhibition of the growth of human cancer cells in vitro and in vivo.
GA decreases the expression of MMPs MMPs mRNA levels in A375.S2 human melanoma cells in stimulating the cancer cell metastasis.
Furthermore, GA processed antimetastatic potential by decreasing the invasiveness of cancer cells.
Moreover, this action of GA was involved in the Ras, p-ERK signaling pathways with function to communicate a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell to induce the inhibition of MMP-2 associated with cancer spreading in A375.S2 human melanoma cells.
Based on the findings, researchers said, " These data, therefore, provide evidence for the role of GA as a potential cancer chemotherapeutic agent, which can markedly inhibit the invasive capacity of melanoma cells".
o
Taken altogether, Comfrey may be considered a remedy to inhibit cancer call spreading, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Gallic acid inhibits the migration and invasion of A375.S2 human melanoma cells through the inhibition of matrix metalloproteinase-2 and Ras by Lo C1, Lai TY, Yang JS, Yang JH, Ma YS, Weng SW, Lin HY, Chen HY, Lin JG, Chung JG. (PubMed)
Tuesday, April 21, 2020
Dandelion (Taraxacum officinale), the Best Antioxidant Functional Herbal Medicine
Antioxidants are stable atoms that inhibit oxidation caused by free radicals.
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.
Believe it or not, free radicals also play a critical role in maintaining a certain body function. The Journal of Physiology showed that free radicals act as signal substances that cause the heart to beat with the correct force.
In healthy individuals, antioxidant enzymes produced by the liver are good enough to balance the free radical produced by the cell metabolism and external sources such as the air we breathe and the food we eat.
However, in people with a weakened immune system such as infants, children and the elderly, dietary sources from supplements, fruits and vegetables may be needed.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world.
The herbal medicine has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined in vitro and in vivo the antioxidant effects of 70% ethanol-water (v/v) leaf and root extracts of T. officinale (TOL and TOR, respectively).
The study included organ homogenate samples from Nω-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, treated by leaf extracts of TOL (500 mg/kg/day) and TOR (500 mg/kg/day) for 21 days.
Based on the results from the experiment, the antioxidant contents of ) polyphenol (4.35 ± 0.15 compared to 1.14 ± 0.01) and flavonoid (23.17 ± 0.14 compared to 3 ± 0.05) of TOL are significantly higher compared to TOR.
TOL exerted a significantly higher free radical scavenging activity (EC50 0.37 compared to 1.34 mg/mL) and total antioxidant capacities (82.56% compared to 61.54% ABTS, and 156 ± 5.28 compared to 40 ± 0.31 FRAP) compared to TOR.
Furthermore, both extracts inhibited the oxidative stress marker MDA levels and increased the total antioxidant capacity (TAC) without inducing toxicity with LD50 > 5000 mg/kg).
Collectively, T. officinale leaf extract possesses significant anti-oxidant effects that conferred significant in vivo antioxidant protection against free radical-mediated oxidative stress in L-NAME-induced hypertensive rats.
Taken altogether, dandelion may be considered a remedy for enhancing the antioxidant capacity against oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In Vitro and In Vivo Antioxidant Properties of Taraxacum officinale in Nω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats by Aremu OO1, Oyedeji AO2, Oyedeji OO3, Nkeh-Chungag BN4, Rusike CRS, (PubMed)
Free radicals are highly reactive molecules with an unpaired electron on the outer ring of the atom.
Due to its nature to become stable, free radicals readily to donate or steal an electron from other molecules, leading to the chain of domino's effect that can not be stopped until either the electrons are paired or inhibited by antioxidants.
This chain of reaction is the cause of oxidative stress, a condition is associated with either overexpression of free radicals or depletion of antioxidant enzymes produced by the host organs.
Overexpression of free radicals is known to cause damage in contributing to the etiology of many chronic health problems such as cardiovascular and inflammatory disease, cataracts, and cancer.
Antioxidants, on the other hand, are stable molecules with a unique function in the inhibition of oxidation.
Believe it or not, free radicals also play a critical role in maintaining a certain body function. The Journal of Physiology showed that free radicals act as signal substances that cause the heart to beat with the correct force.
In healthy individuals, antioxidant enzymes produced by the liver are good enough to balance the free radical produced by the cell metabolism and external sources such as the air we breathe and the food we eat.
However, in people with a weakened immune system such as infants, children and the elderly, dietary sources from supplements, fruits and vegetables may be needed.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world.
The herbal medicine has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined in vitro and in vivo the antioxidant effects of 70% ethanol-water (v/v) leaf and root extracts of T. officinale (TOL and TOR, respectively).
The study included organ homogenate samples from Nω-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats, treated by leaf extracts of TOL (500 mg/kg/day) and TOR (500 mg/kg/day) for 21 days.
Based on the results from the experiment, the antioxidant contents of ) polyphenol (4.35 ± 0.15 compared to 1.14 ± 0.01) and flavonoid (23.17 ± 0.14 compared to 3 ± 0.05) of TOL are significantly higher compared to TOR.
TOL exerted a significantly higher free radical scavenging activity (EC50 0.37 compared to 1.34 mg/mL) and total antioxidant capacities (82.56% compared to 61.54% ABTS, and 156 ± 5.28 compared to 40 ± 0.31 FRAP) compared to TOR.
Furthermore, both extracts inhibited the oxidative stress marker MDA levels and increased the total antioxidant capacity (TAC) without inducing toxicity with LD50 > 5000 mg/kg).
Collectively, T. officinale leaf extract possesses significant anti-oxidant effects that conferred significant in vivo antioxidant protection against free radical-mediated oxidative stress in L-NAME-induced hypertensive rats.
Taken altogether, dandelion may be considered a remedy for enhancing the antioxidant capacity against oxidative stress, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) In Vitro and In Vivo Antioxidant Properties of Taraxacum officinale in Nω-Nitro-l-Arginine Methyl Ester (L-NAME)-Induced Hypertensive Rats by Aremu OO1, Oyedeji AO2, Oyedeji OO3, Nkeh-Chungag BN4, Rusike CRS, (PubMed)
Monday, April 20, 2020
Herbal Turmeric Protects the Heart Against Cardiac Toxicity
Cardiac toxicity is a condition in which the heart has been damage to some extents caused by harmful chemicals, including toxins induced by the treatment of chemotherapy.
Depending on the cells of the areas of the heart that have been damaged, cardiac toxicity includes
* Cardiomyopathy is a disorder caused a weaken or damage of heart muscle, affecting the heart rhythm or inducing the risk of heart failure.
* Myocarditis is a condition of inflammation of the heart, that can lead to changes in heart rhythm or heart failure.
* Pericarditis is a condition caused by the inflammation of the sac surrounding the heart, inducing chest pain or heart failure.
* Acute coronary syndromes that affect the blood flow due to blood vessel damage.
* Congestive heart failure is a result that affects the function of the heart in pumping blood throughout the body.
Conventionally, treatment of cardiac toxicity includes medication to control fluids, high blood pressure, and medications which improve heart functioning. If all aforementioned medications fail, a heart transplant may be necessary.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of cardiac toxicity scientists launched an investigation to determine whether curry intake reduces blood levels of heavy metals, according to the Korean National Health and Nutrition Examination Survey 2013 data.
1,350 participants selected for the study were randomly divided into either curry intake group with the consumption of a curry dish more than once a month over the previous year, or a non-curry intake group (n = 747).
According to the heavy metal analysis, the curry intake group showed significantly lower heavy metal blood concentrations (Pb, Hg, and Cd).
Furthermore, the levels of heavy metals in patients with hypertension (HTN) were significantly lower in the curry intake group compared to the nonhypertension group.
The levels of blood concentrations of heavy metals induced toxicity associated with the induction of hypertension were significantly lower compared to the placebo.
The results confirmed the correlation between blood heavy metal levels and HTN.
In other words, turmeric has a potential effect on reducing cardiac toxicity in the induction of abnormally blood pressure.
In order to obtain turmeric detoxed activity, researchers examined the protective effect of turmeric extract against doxorubicin (DOX)-induced cardiac toxicity in rats.
According to the tested assays, turmeric extract exerted multiple therapeutic activities that ameliorate the effect of DOX-induced cardiac toxicity.
Additionally, turmeric extract inhibited the DOX-induced increase in plasma cholesterol, LDH, associated with the increased risk of cardiovascular disease.
Dr. Mohamad RH, the lead scientist said, "The present findings conclude that the turmeric extract has multiple therapeutic activities that block the cardiac,.....toxicities".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of cardiac toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Reduction in Prevalence of Hypertension and Blood Heavy Metals among Curry-Consumed Korean by Choi JW1, Oh C2, Shim SY1,3, Jeong S4, Kim HS5, Kim MS. (PubMed)
(2)The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats by Mohamad RH1, El-Bastawesy AM, Zekry ZK, Al-Mehdar HA, Al-Said MG, Aly SS, Sharawy SM, El-Merzabani MM. (PubMed)
Depending on the cells of the areas of the heart that have been damaged, cardiac toxicity includes
* Cardiomyopathy is a disorder caused a weaken or damage of heart muscle, affecting the heart rhythm or inducing the risk of heart failure.
* Myocarditis is a condition of inflammation of the heart, that can lead to changes in heart rhythm or heart failure.
* Pericarditis is a condition caused by the inflammation of the sac surrounding the heart, inducing chest pain or heart failure.
* Acute coronary syndromes that affect the blood flow due to blood vessel damage.
* Congestive heart failure is a result that affects the function of the heart in pumping blood throughout the body.
Conventionally, treatment of cardiac toxicity includes medication to control fluids, high blood pressure, and medications which improve heart functioning. If all aforementioned medications fail, a heart transplant may be necessary.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and for the treatment of flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
On finding a natural compound for the treatment of cardiac toxicity scientists launched an investigation to determine whether curry intake reduces blood levels of heavy metals, according to the Korean National Health and Nutrition Examination Survey 2013 data.
1,350 participants selected for the study were randomly divided into either curry intake group with the consumption of a curry dish more than once a month over the previous year, or a non-curry intake group (n = 747).
According to the heavy metal analysis, the curry intake group showed significantly lower heavy metal blood concentrations (Pb, Hg, and Cd).
Furthermore, the levels of heavy metals in patients with hypertension (HTN) were significantly lower in the curry intake group compared to the nonhypertension group.
The levels of blood concentrations of heavy metals induced toxicity associated with the induction of hypertension were significantly lower compared to the placebo.
The results confirmed the correlation between blood heavy metal levels and HTN.
In other words, turmeric has a potential effect on reducing cardiac toxicity in the induction of abnormally blood pressure.
In order to obtain turmeric detoxed activity, researchers examined the protective effect of turmeric extract against doxorubicin (DOX)-induced cardiac toxicity in rats.
According to the tested assays, turmeric extract exerted multiple therapeutic activities that ameliorate the effect of DOX-induced cardiac toxicity.
Additionally, turmeric extract inhibited the DOX-induced increase in plasma cholesterol, LDH, associated with the increased risk of cardiovascular disease.
Dr. Mohamad RH, the lead scientist said, "The present findings conclude that the turmeric extract has multiple therapeutic activities that block the cardiac,.....toxicities".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin may be considered supplements for the prevention of cardiac toxicity, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Reduction in Prevalence of Hypertension and Blood Heavy Metals among Curry-Consumed Korean by Choi JW1, Oh C2, Shim SY1,3, Jeong S4, Kim HS5, Kim MS. (PubMed)
(2)The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats by Mohamad RH1, El-Bastawesy AM, Zekry ZK, Al-Mehdar HA, Al-Said MG, Aly SS, Sharawy SM, El-Merzabani MM. (PubMed)
Sunday, April 19, 2020
Herbal Angelica Processes Anti-Depression Activity in Vivo
Depression is a common and serious psychological illness, affecting the physical and mental functions of patients, including the ways patients feel, think and act.
Some patients with depression may feel sadness and/or a loss of interest in activities once enjoyed.
There are many causes associated with the onset of depression, including genetics, changes in hormone levels, certain medical conditions, stress, grief or difficult life circumstances that initiate the change of brain chemistry in inducing depressive syndrome.
The most common symptoms of depression include sadness, hopelessness, guilt, change of mood, loss of interest in friends, family, favorite activities, and sex.
Some patients with depression also experience cognitive symptoms of trouble concentrating, making decisions, remembering and thoughts of harming themselves.
People who act out of the ordinary, consist of undesirable behavior result in impairment in the individual's functioning are considered to have abnormal behavior.
Undesirable behavior or abnormal behavior has been found in many patients with chronic depression.
According to the statistics, over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself.
Antidepressant is a type of conventional medicine used as a first-line treatment of depression.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a herbal medicine for the treatment of depression and depressive symptoms, researchers examined the antidepressant effects of PAPZ (Panax ginseng, Angelica Sinensis, Polygala tenuifolia Willd, and Ziziphi spinose Semen) on corticosterone (CORT) model of depression in mice.
According to the experimental results, the administration of PAPZ ameliorated depression-like phenotypes in the CORT model.
Furthermore, chronic PAPZ administration exhibited the protein expression of brain-derived neurotrophic factor (BDNF) in the hippocampal tissue of the depressive mice.
Moreover, levels of the antioxidant enzyme activity of superoxide dismutase were enhanced compared to the decrease of the levels of stress marker malondialdehyde levels in the hippocampal tissue.
Based on the evidence, researchers said, "PAPZ has therapeutic effects in a mice depression model through increasing protein expression of BDNF and improving the anti-oxidation ability of the brain".
Taken altogether, Herbal Angelica processes anti-depressant activity, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Chinese Herbal Formula PAPZ Ameliorates Behavioral Abnormalities in Depressive Mice by Chen H1, Huang Q2,3, Zhang S4,5, Hu K6, Xiong W7, Xiao L8, Cong R9, Liu Q10, Wang Z. (PubMed)
Some patients with depression may feel sadness and/or a loss of interest in activities once enjoyed.
There are many causes associated with the onset of depression, including genetics, changes in hormone levels, certain medical conditions, stress, grief or difficult life circumstances that initiate the change of brain chemistry in inducing depressive syndrome.
The most common symptoms of depression include sadness, hopelessness, guilt, change of mood, loss of interest in friends, family, favorite activities, and sex.
Some patients with depression also experience cognitive symptoms of trouble concentrating, making decisions, remembering and thoughts of harming themselves.
People who act out of the ordinary, consist of undesirable behavior result in impairment in the individual's functioning are considered to have abnormal behavior.
Undesirable behavior or abnormal behavior has been found in many patients with chronic depression.
According to the statistics, over 30 million Americans suffer from depression and the amount is increasing at an alarming rate. Depression may be a mental health disorder that can affect the way you eat, sleep, and the way you feel about yourself.
Antidepressant is a type of conventional medicine used as a first-line treatment of depression.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a herbal medicine for the treatment of depression and depressive symptoms, researchers examined the antidepressant effects of PAPZ (Panax ginseng, Angelica Sinensis, Polygala tenuifolia Willd, and Ziziphi spinose Semen) on corticosterone (CORT) model of depression in mice.
According to the experimental results, the administration of PAPZ ameliorated depression-like phenotypes in the CORT model.
Furthermore, chronic PAPZ administration exhibited the protein expression of brain-derived neurotrophic factor (BDNF) in the hippocampal tissue of the depressive mice.
Moreover, levels of the antioxidant enzyme activity of superoxide dismutase were enhanced compared to the decrease of the levels of stress marker malondialdehyde levels in the hippocampal tissue.
Based on the evidence, researchers said, "PAPZ has therapeutic effects in a mice depression model through increasing protein expression of BDNF and improving the anti-oxidation ability of the brain".
Taken altogether, Herbal Angelica processes anti-depressant activity, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The Chinese Herbal Formula PAPZ Ameliorates Behavioral Abnormalities in Depressive Mice by Chen H1, Huang Q2,3, Zhang S4,5, Hu K6, Xiong W7, Xiao L8, Cong R9, Liu Q10, Wang Z. (PubMed)
Saturday, April 18, 2020
Herbal Dandelion (Taraxacum officinale) Reduces the Side Effect of Chemo Drug Induce-Anorexia
Eating Disorders are a group of abnormal eating habits associated with a person's preoccupation weight, involving either insufficient or excessive food intake.
Eating disorders can be classified into
* Anorexia nervosa is a type of eating disorder usually develop in the teen years and affects over 90% of females, because of excessive food restriction and irrational fear to become fat due to the wrongly influenced media as attractiveness is equated to thinness.
* Bulimia nervosa
Bulimia nervosa is a medical condition of consuming a large amount of food in a short amount of time or one setting (binge eating), followed by self-induced vomiting, and taking a laxative or diuretic and/or excessive exercise, etc. to compensate for the binge. Bulimia Nervosa also affects almost 90% of females.
* Binge eating disorder
Binge eating disorder is a medical condition of compulsive eating of huge amounts of food while feeling out of control and powerless to stop. It is a common eating disorder in the United States affecting 3.5% of females and 2% of males.
Most common symptoms of Anorexia nervosa are
* Weight loss, sometimes severe as a result of malnutrition.
* Refusal to maintain a normal or minimally above normal body mass index for their age and Dieting despite being thin or dangerously underweight
* Intense fear of gaining weight and primary or secondary amenorrhea
In the study Eating disorders. A review and update by Haller E. at the University of California indicated Anorexia nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(2).
* Obsession with calories and fat content of food and try to avoid eating altogether. They deny hunger and will usually avoid eating around others as well as avoiding situations where food might be present(3).
* Disturbance to body image the person hold of him/herself
In the study of Eating disorders. A review and update, Dr. E Haller indicated that anorexia Nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(4).
*Abdominal pain and distention
Anorexia nervosa is also associated with abdominal and with a sensation of elevated abdominal pressure.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of eating disorders in chemotherapy patients, scientists examined the anti-anorexia of herbal mixtures extracts LCBP‑Anocure‑16001‑3 (LA16001, LA16002, LA16003), composed of Atractylodes japonica, Angelica Gigas, Astragalus membranaceus, Lonicera japonica Thunb., Taraxacum Platycerium H. Dahlstedt and Prunella vulgaris var. Asiatica (Nakai) Hara.
In a cisplatin‑induced anorexia mouse model, treatment with LA16001 prevents body weight loss. However, all three extracts were demonstrated to improve food intake.
LA16001showed to altered expression levels of ghrelin, leptin, and interleukin‑6 associated with infection.
In other words, LA16001 modulated the interleukin‑6 activation of phosphring the caorylation of Janus kinase 1 and signal transducer and activator of transcription 3 during the course of infection induce-inflammation observed by the increase of the number of white blood cells and neutrophils.
Based on the findings, researchers said, " the herbal formula LA16001 may be able to prevent chemotherapy‑induced anorexia and may have potential as a novel therapeutic strategy for the adjuvant treatment of patients with cancer".
Taken altogether, dandelion may be used to enhance and prevent side effect in a combination with chemo drugs in chemotherapy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia by Woo SM1, Lee KM2, Lee GR2, Park JY2, Lee HJ2, Bahn HJ2, Yoon HS2, Kim JY2, Shin YC3, Cho SG4, Ko SG. (PubMed)
(2) Eating Disorders: Anorexia nervosa - Symptoms and Signs by Kyle J. Norton
Eating disorders can be classified into
* Anorexia nervosa is a type of eating disorder usually develop in the teen years and affects over 90% of females, because of excessive food restriction and irrational fear to become fat due to the wrongly influenced media as attractiveness is equated to thinness.
* Bulimia nervosa
Bulimia nervosa is a medical condition of consuming a large amount of food in a short amount of time or one setting (binge eating), followed by self-induced vomiting, and taking a laxative or diuretic and/or excessive exercise, etc. to compensate for the binge. Bulimia Nervosa also affects almost 90% of females.
* Binge eating disorder
Binge eating disorder is a medical condition of compulsive eating of huge amounts of food while feeling out of control and powerless to stop. It is a common eating disorder in the United States affecting 3.5% of females and 2% of males.
Most common symptoms of Anorexia nervosa are
* Weight loss, sometimes severe as a result of malnutrition.
* Refusal to maintain a normal or minimally above normal body mass index for their age and Dieting despite being thin or dangerously underweight
* Intense fear of gaining weight and primary or secondary amenorrhea
In the study Eating disorders. A review and update by Haller E. at the University of California indicated Anorexia nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(2).
* Obsession with calories and fat content of food and try to avoid eating altogether. They deny hunger and will usually avoid eating around others as well as avoiding situations where food might be present(3).
* Disturbance to body image the person hold of him/herself
In the study of Eating disorders. A review and update, Dr. E Haller indicated that anorexia Nervosa is diagnosed when a person refuses to maintain his or her body weight over a minimally normal weight for age and height, such as 15% below that expected, has an intense fear of gaining weight, has a disturbed body image, and, in women, has primary or secondary amenorrhea(4).
*Abdominal pain and distention
Anorexia nervosa is also associated with abdominal and with a sensation of elevated abdominal pressure.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
On finding a natural ingredient for the treatment of eating disorders in chemotherapy patients, scientists examined the anti-anorexia of herbal mixtures extracts LCBP‑Anocure‑16001‑3 (LA16001, LA16002, LA16003), composed of Atractylodes japonica, Angelica Gigas, Astragalus membranaceus, Lonicera japonica Thunb., Taraxacum Platycerium H. Dahlstedt and Prunella vulgaris var. Asiatica (Nakai) Hara.
In a cisplatin‑induced anorexia mouse model, treatment with LA16001 prevents body weight loss. However, all three extracts were demonstrated to improve food intake.
LA16001showed to altered expression levels of ghrelin, leptin, and interleukin‑6 associated with infection.
In other words, LA16001 modulated the interleukin‑6 activation of phosphring the caorylation of Janus kinase 1 and signal transducer and activator of transcription 3 during the course of infection induce-inflammation observed by the increase of the number of white blood cells and neutrophils.
Based on the findings, researchers said, " the herbal formula LA16001 may be able to prevent chemotherapy‑induced anorexia and may have potential as a novel therapeutic strategy for the adjuvant treatment of patients with cancer".
Taken altogether, dandelion may be used to enhance and prevent side effect in a combination with chemo drugs in chemotherapy, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia by Woo SM1, Lee KM2, Lee GR2, Park JY2, Lee HJ2, Bahn HJ2, Yoon HS2, Kim JY2, Shin YC3, Cho SG4, Ko SG. (PubMed)
(2) Eating Disorders: Anorexia nervosa - Symptoms and Signs by Kyle J. Norton
Friday, April 17, 2020
Turmeric's Bioactive Compound Curcumin Protects Diabetics Against Diabetic cardiomyopathy
Diabetic cardiomyopathy is a complication found in patients with diabetes associated with reducing the heart function in circulating blood through the body, leading to heart failure and increased the accumulation of fluid in the lungs.
Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.
* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.
* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.
The most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.
At the early stage, most patients with diabetic cardiomyopathy are asymptomatic. However, mild left ventricular diastolic dysfunction with little effect on ventricular filling and concomitant hypertension or coronary artery disease has been found to be the early indication of diabetic cardiomyopathy in patients with diabetes.
Epidemiologically, the most common risk factors that increase the risk of diabetic cardiomyopathy. are insulin resistance, hyperinsulinemia, and hyperglycemia.
Conventionally, as of today, there is no effective treatment of diabetic cardiomyopathy. Medication used for the treatment of the condition is focusing on glycemic control and management of heart failure symptoms.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic cardiomyopathy(DCM), researchers examined the effect of curcumin on modulating DCM and the mechanisms involved.
The study included an experimental diabetic rat model induced by a low dose of streptozotocin(STZ) combined with high energy intake on rats, followed by curcumin orally administrated at a dose of 100 or 200 mg · kg(-1) · d(-1), respectively.
Before the treatment of curcumin, induced DCM rats showed a declined systolic myocardial performance associated with myocardial hypertrophy and fibrosis accompanied by the metabolism abnormalities, aberrant myocardial enzymes, and increased AGEs (advanced glycation end-products) accumulation.
Increased levels of ROS and depletion of antioxidant enzymes were also found in the rat before pretreatment with curcumin, observed by increased oxidative stress markers.
Furthermore, levels of pro-apoptotic proteins and proinflammatory cytokines were also found to significantly increase in DCM rats.
After the injection of curcumin, researchers found that remarkably, the bioactive compound attenuated myocardial dysfunction, cardiac fibrosis, AGEs accumulation, oxidative stress, inflammation and apoptosis in the heart of diabetic rats.
In other words, curcumin protected the heart of DCM rats against the onset of diabetic cardiomyopathy(DCM).
Based on the results, researchers said, "these results suggest that curcumin may have great therapeutic potential in the treatment of DCM, and perhaps other cardiovascular disorders, by attenuating fibrosis, oxidative stress, inflammation, and cell death".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered a supplement for the prevention and treatment of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy by Zheng J1, Cheng J2, Zheng S3, Feng Q3, Xiao X. (PubMed)
(2) Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats by Yu W1, Wu J, Cai F, Xiang J, Zha W, Fan D, Guo S, Ming Z, Liu C. (PubMed)
Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.
* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.
* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.
The most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.
At the early stage, most patients with diabetic cardiomyopathy are asymptomatic. However, mild left ventricular diastolic dysfunction with little effect on ventricular filling and concomitant hypertension or coronary artery disease has been found to be the early indication of diabetic cardiomyopathy in patients with diabetes.
Epidemiologically, the most common risk factors that increase the risk of diabetic cardiomyopathy. are insulin resistance, hyperinsulinemia, and hyperglycemia.
Conventionally, as of today, there is no effective treatment of diabetic cardiomyopathy. Medication used for the treatment of the condition is focusing on glycemic control and management of heart failure symptoms.
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the urgency to find a potential ingredient for the treatment of diabetic cardiomyopathy(DCM), researchers examined the effect of curcumin on modulating DCM and the mechanisms involved.
The study included an experimental diabetic rat model induced by a low dose of streptozotocin(STZ) combined with high energy intake on rats, followed by curcumin orally administrated at a dose of 100 or 200 mg · kg(-1) · d(-1), respectively.
Before the treatment of curcumin, induced DCM rats showed a declined systolic myocardial performance associated with myocardial hypertrophy and fibrosis accompanied by the metabolism abnormalities, aberrant myocardial enzymes, and increased AGEs (advanced glycation end-products) accumulation.
Increased levels of ROS and depletion of antioxidant enzymes were also found in the rat before pretreatment with curcumin, observed by increased oxidative stress markers.
Furthermore, levels of pro-apoptotic proteins and proinflammatory cytokines were also found to significantly increase in DCM rats.
After the injection of curcumin, researchers found that remarkably, the bioactive compound attenuated myocardial dysfunction, cardiac fibrosis, AGEs accumulation, oxidative stress, inflammation and apoptosis in the heart of diabetic rats.
In other words, curcumin protected the heart of DCM rats against the onset of diabetic cardiomyopathy(DCM).
Based on the results, researchers said, "these results suggest that curcumin may have great therapeutic potential in the treatment of DCM, and perhaps other cardiovascular disorders, by attenuating fibrosis, oxidative stress, inflammation, and cell death".
Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered a supplement for the prevention and treatment of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy by Zheng J1, Cheng J2, Zheng S3, Feng Q3, Xiao X. (PubMed)
(2) Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats by Yu W1, Wu J, Cai F, Xiang J, Zha W, Fan D, Guo S, Ming Z, Liu C. (PubMed)
Thursday, April 16, 2020
Herbal Cascara Sagrada's Emodin Which Inhibits Pancreatic Cancer Cells Against Spreading
Scientists may have found a functional herb bioactive compound which processes anti-pancreatic cancer activity with no side effects, some scientists suggested.
Pancreatic cancer is a medical and chronic condition characterized by irregular cells growth in the tissue of the pancreas.
In the early stage, pancreatic cancer starts on the cells of the surface of the inner lining of pancreatic tissue. At the advanced stage, cancerous cells of the pancreas can travel a distance away to invade other healthy tissue and organs.
The exact causes of the alternation of DNA of pancreatic cells are unknown. However, epidemiological studies suggested that genetic preposition and acquired gene mutations are associated with the increased incidence of cancer.
Some researchers suggested long-term use of tobacco, being overweight and obese, exposure to workplace chemicals, age, gender and family history are some prevalent risk factors of pancreatic cancer.
According to the statistic, pancreatic cancer is the eighth most common cancer in women and the fourth leading cause of cancer death in men and women. cancer accounts for 7% of all cancer deaths.
The 5 years survival rate at stage 1 and 2 is 61% and 52% respectively.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America.
The herbal's bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing effect.
Besides the main compound of anthraquinones, the herb also contains anthraquinone glycosides, (emodin, frangulin, iso-emodin, aloe-emodin, and chrysophanol), rhein, aloin, malic acid, tannic acid, cascarosides A, B, C, and D, and hydroxy anthracene derivatives (HAD), etc.
In the study to reaffirm the Emodin anti-pancreatic cancer effect through inducing apoptosis of pancreatic cancer cells and inhibit tumor growth, researchers at the Zhejiang University School of Medicine, launched an investigation to find out whether emodin could inhibit the angiogenesis of pancreatic cancer tissues and its mechanism.
In vitro and in vivo Emodin inhibited pancreatic cancer cell growth, induced apoptosis, and enhanced the anti-tumor effect of gemcitabine on pancreatic cancer cells by inhibiting the activity of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), the protein in response to cellular survival
Emodin inhibited tumor angiogenesis in vitro and in implanted pancreatic cancer tissues, decreased the expression of angiogenesis-associated factors and reduced eNOS phosphorylation in cell proliferation.
However, Emodin had no effect on VEGFR expression in vivo.
Dr. Lin SZ, the lead author said, "emodin has a potential anti-tumor effect on pancreatic cancer via its dual role in the promotion of apoptosis and suppression of angiogenesis".
Additionally, in the examine the effects of an X-linked inhibitor of apoptosis (XIAP) and NF-κB in chemotherapy resistance in pancreatic cancer, researchers conducted an investigation of SW1990 cells treated by sodium chloride, gemcitabine, emodin or their combination (gemcitabine plus emodin).
The combination therapy of gemcitabine plus emodin) is more effective in inducing a significantly inhibited SW1990 cell growth and a higher percentage of apoptosis than monotherapy.
Gemcitabine upregulated the expression of XIAP and NF-κB, while emodin or emodin plus gemcitabine downregulated them compared to the control group in vitro.
In SW1990 cells established orthotopic pancreatic tumor models in nude mice. The combination of emodin and gemcitabine showed a significant reduction in the tumor to tumor (T/NT) ratio, Standardized uptake value (SUV) and tumor weight compared to monotherapy.
Dr. Wang ZH, the lead author after taking into account of co and confounders wrote:" emodin enhances the antitumor effect of gemcitabine in SW1990 pancreatic cancer in vitro and in vivo, which may be via the downregulation of NF-κB expression, thus inhibiting the expression of XIAP.".
Taken altogether, herbal Cascara sagrada process high amount of bioactive ingredient Emodon may be considered a function in the prevention and an adjunct therapy combined with chemo intervention of treatment of pancreatic cancer, pending to the results of large example size and multi-center studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis by Lin SZ, Wei WT, Chen H, Chen KJ, Tong HF, Wang ZH, Ni ZL, Liu HB, Guo HC, Liu DL. (PubMed)
2. Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo by Wang ZH, Chen H, Guo HC, Tong HF, Liu JX, Wei WT, Tan W, Ni ZL, Liu HB, Lin SZ.(PubMed)
3. [Toxic hepatitis following consumption of the herbal medicinal product Cascara Sagrada].[Article in Danish]" by Jacobsen C, Semb S, Kromann-Andersen H(PubMed)
4. "Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity" by Nadir A, Reddy D, Van Thiel DH. (PubMed)
5. "Occupational respiratory allergic disease induced by Passiflora alata and Rhamnus purshiana" by Giavina-Bianchi PF Jr, Castro FF, Machado ML, Duarte AJ. (PubMed)
Pancreatic cancer is a medical and chronic condition characterized by irregular cells growth in the tissue of the pancreas.
In the early stage, pancreatic cancer starts on the cells of the surface of the inner lining of pancreatic tissue. At the advanced stage, cancerous cells of the pancreas can travel a distance away to invade other healthy tissue and organs.
The exact causes of the alternation of DNA of pancreatic cells are unknown. However, epidemiological studies suggested that genetic preposition and acquired gene mutations are associated with the increased incidence of cancer.
Some researchers suggested long-term use of tobacco, being overweight and obese, exposure to workplace chemicals, age, gender and family history are some prevalent risk factors of pancreatic cancer.
According to the statistic, pancreatic cancer is the eighth most common cancer in women and the fourth leading cause of cancer death in men and women. cancer accounts for 7% of all cancer deaths.
The 5 years survival rate at stage 1 and 2 is 61% and 52% respectively.
Cascara sagrada is a species of buckthorn, genus Rhamnus, belonging to the family Rhamnaceae, native to western North America.
The herbal's bark has been used in traditional medicine for gastrointestinal support. and it is thought to have a laxative and natural cleansing effect.
Besides the main compound of anthraquinones, the herb also contains anthraquinone glycosides, (emodin, frangulin, iso-emodin, aloe-emodin, and chrysophanol), rhein, aloin, malic acid, tannic acid, cascarosides A, B, C, and D, and hydroxy anthracene derivatives (HAD), etc.
In the study to reaffirm the Emodin anti-pancreatic cancer effect through inducing apoptosis of pancreatic cancer cells and inhibit tumor growth, researchers at the Zhejiang University School of Medicine, launched an investigation to find out whether emodin could inhibit the angiogenesis of pancreatic cancer tissues and its mechanism.
In vitro and in vivo Emodin inhibited pancreatic cancer cell growth, induced apoptosis, and enhanced the anti-tumor effect of gemcitabine on pancreatic cancer cells by inhibiting the activity of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), the protein in response to cellular survival
Emodin inhibited tumor angiogenesis in vitro and in implanted pancreatic cancer tissues, decreased the expression of angiogenesis-associated factors and reduced eNOS phosphorylation in cell proliferation.
However, Emodin had no effect on VEGFR expression in vivo.
Dr. Lin SZ, the lead author said, "emodin has a potential anti-tumor effect on pancreatic cancer via its dual role in the promotion of apoptosis and suppression of angiogenesis".
Additionally, in the examine the effects of an X-linked inhibitor of apoptosis (XIAP) and NF-κB in chemotherapy resistance in pancreatic cancer, researchers conducted an investigation of SW1990 cells treated by sodium chloride, gemcitabine, emodin or their combination (gemcitabine plus emodin).
The combination therapy of gemcitabine plus emodin) is more effective in inducing a significantly inhibited SW1990 cell growth and a higher percentage of apoptosis than monotherapy.
Gemcitabine upregulated the expression of XIAP and NF-κB, while emodin or emodin plus gemcitabine downregulated them compared to the control group in vitro.
In SW1990 cells established orthotopic pancreatic tumor models in nude mice. The combination of emodin and gemcitabine showed a significant reduction in the tumor to tumor (T/NT) ratio, Standardized uptake value (SUV) and tumor weight compared to monotherapy.
Dr. Wang ZH, the lead author after taking into account of co and confounders wrote:" emodin enhances the antitumor effect of gemcitabine in SW1990 pancreatic cancer in vitro and in vivo, which may be via the downregulation of NF-κB expression, thus inhibiting the expression of XIAP.".
Taken altogether, herbal Cascara sagrada process high amount of bioactive ingredient Emodon may be considered a function in the prevention and an adjunct therapy combined with chemo intervention of treatment of pancreatic cancer, pending to the results of large example size and multi-center studies.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
1. Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis by Lin SZ, Wei WT, Chen H, Chen KJ, Tong HF, Wang ZH, Ni ZL, Liu HB, Guo HC, Liu DL. (PubMed)
2. Enhanced antitumor efficacy by the combination of emodin and gemcitabine against human pancreatic cancer cells via downregulation of the expression of XIAP in vitro and in vivo by Wang ZH, Chen H, Guo HC, Tong HF, Liu JX, Wei WT, Tan W, Ni ZL, Liu HB, Lin SZ.(PubMed)
3. [Toxic hepatitis following consumption of the herbal medicinal product Cascara Sagrada].[Article in Danish]" by Jacobsen C, Semb S, Kromann-Andersen H(PubMed)
4. "Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity" by Nadir A, Reddy D, Van Thiel DH. (PubMed)
5. "Occupational respiratory allergic disease induced by Passiflora alata and Rhamnus purshiana" by Giavina-Bianchi PF Jr, Castro FF, Machado ML, Duarte AJ. (PubMed)
Wednesday, April 15, 2020
Herbal Turmeric Protects Your Skin Against Photo-Damage
Photodamage is a type of skin damage caused by long-term exposure to the sunlight or tanning bed.
Photodamage skin is one most common form of skin damage in the US, due to misunderstanding the benefits and adverse effects on light exposure.
Believe it or not, a quarter of lifetime sun exposure occurs before the end of the teenage years. Most cases of photo skin damage can also stimulate some unwanted skin conditions, including advanced aging or wrinkling, uneven skin, hyperpigmentation, telangiectasias, actinic keratoses liver, and age spots.
In severe cases, long-term photodamage skin can also lead to skin cancer. More people in the US are diagnosed with skin cancer each year than all other cancers combined.
According to the statistic, 1 in 5 Americans will develop skin cancer by the age of 70.
Conventionally, most cases of early-stage and mild damage of skin are treated by topical Levulan that remove scaly patches of actinic keratoses from your skin.
However, Laser surgery may be necessary, if the topical fails.
Dr. Jee SH, the lead scientist in the examination of the risk of photodamaged skin in the risk of skin cancer wrote, "Some workers in paraquat manufacturing, exposed to bipyridines, have developed pigmentation and keratosis on sun-exposed skin".
And, "This pathologic study proves that all the lesions showed either photodamage or skin cancer. The strong trend in the correlation between the severity of photodamage and exposure to bipyridine leads to speculation about the synergistic role of bipyridine exposure and the solar effect in causing these malignant and premalignant skin lesions".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the concerns of Ultraviolet B (UVB) irradiation in inducing skin photo-damage associated with the onset of a sunburn, erythema, photoaging, and photocarcinogenesis, researchers evaluated the protective effects of curcumin against acute photo-damage.
In hairless mice, topical application of curcumin exerted a kin protective effect by significantly inhibiting acute UVB (540 mJ cm-2 , for 3 successive days)-induced inflammatory cells, collagen accrementition derangement, and lipid peroxidation.
Additionally, the topical cream with curcumin also stimulated the NF-E2-related factor 2 (Nrf2) nuclear accumulation involved in skin defense on uncovered (Uncv) hairless mice skin.
In vitro, treatment of HaCaT cells with curcumin significantly attenuated acute UVB (300 mJ cm-2 ) tissue damage in releasing lactate dehydrogenase release (LDH) into the bloodstream.
Levels of intracellular reactive oxygen species production and DNA damage are also inhibited by the injection of curcumin by activating the expression of phase II detoxifying enzymes and promoting DNA repair activity.
Additional analysis of the skin protective activity of curcumin, researchers found that The photoprotective effect provided by curcumin was potentially associated with modulation of Nrf2-factor associated with antioxidant defense.
In order to reveal more information about the effects of turmeric anti-skin damage, researchers looked into the turmeric and turmeric-containing polyherbal combination tablets versus placebo on facial redness.
The prospective, double-blind, randomized pilot study included 33 healthy participants were recruited from the dermatology clinic at the University of California, Davis and nearby community from 2016 to 2017 receive one of three interventions (placebo, turmeric or polyherbal combination tablets) and were told to take the intervention tablets by mouth twice daily for 4 weeks.
According to the results, the polyherbal combination group had a significant decrease in redness of 40% compared to baseline (P = 0.03) compared to that of placebo and turmeric groups with no statistically significant changes in image analysis-based facial redness.
Based on the findings, researchers said, "Polyherbal combination tablet supplementation improved facial redness compared to the turmeric or placebo".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin used alone or combined with other phytochemical may be used for the prevention of skin photo-damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective Effect of Curcumin Against Acute Ultraviolet B Irradiation-induced Photo-damage by Li H1, Gao A1, Jiang N1, Liu Q1, Liang B1, Li R1, Zhang E1, Li Z1, Zhu H. (PubMed)
(2) Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study by Vaughn AR1, Pourang A2, Clark AK2, Burney W2, Sivamani RK. (PubMed)
(3) Photodamage and skin cancer among paraquat workers by Jee SH1, Kuo HW, Su WP, Chang CH, Sun CC, Wang JD. (PubMed)
Photodamage skin is one most common form of skin damage in the US, due to misunderstanding the benefits and adverse effects on light exposure.
Believe it or not, a quarter of lifetime sun exposure occurs before the end of the teenage years. Most cases of photo skin damage can also stimulate some unwanted skin conditions, including advanced aging or wrinkling, uneven skin, hyperpigmentation, telangiectasias, actinic keratoses liver, and age spots.
In severe cases, long-term photodamage skin can also lead to skin cancer. More people in the US are diagnosed with skin cancer each year than all other cancers combined.
According to the statistic, 1 in 5 Americans will develop skin cancer by the age of 70.
Conventionally, most cases of early-stage and mild damage of skin are treated by topical Levulan that remove scaly patches of actinic keratoses from your skin.
However, Laser surgery may be necessary, if the topical fails.
Dr. Jee SH, the lead scientist in the examination of the risk of photodamaged skin in the risk of skin cancer wrote, "Some workers in paraquat manufacturing, exposed to bipyridines, have developed pigmentation and keratosis on sun-exposed skin".
And, "This pathologic study proves that all the lesions showed either photodamage or skin cancer. The strong trend in the correlation between the severity of photodamage and exposure to bipyridine leads to speculation about the synergistic role of bipyridine exposure and the solar effect in causing these malignant and premalignant skin lesions".
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.
The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
In the concerns of Ultraviolet B (UVB) irradiation in inducing skin photo-damage associated with the onset of a sunburn, erythema, photoaging, and photocarcinogenesis, researchers evaluated the protective effects of curcumin against acute photo-damage.
In hairless mice, topical application of curcumin exerted a kin protective effect by significantly inhibiting acute UVB (540 mJ cm-2 , for 3 successive days)-induced inflammatory cells, collagen accrementition derangement, and lipid peroxidation.
Additionally, the topical cream with curcumin also stimulated the NF-E2-related factor 2 (Nrf2) nuclear accumulation involved in skin defense on uncovered (Uncv) hairless mice skin.
In vitro, treatment of HaCaT cells with curcumin significantly attenuated acute UVB (300 mJ cm-2 ) tissue damage in releasing lactate dehydrogenase release (LDH) into the bloodstream.
Levels of intracellular reactive oxygen species production and DNA damage are also inhibited by the injection of curcumin by activating the expression of phase II detoxifying enzymes and promoting DNA repair activity.
Additional analysis of the skin protective activity of curcumin, researchers found that The photoprotective effect provided by curcumin was potentially associated with modulation of Nrf2-factor associated with antioxidant defense.
In order to reveal more information about the effects of turmeric anti-skin damage, researchers looked into the turmeric and turmeric-containing polyherbal combination tablets versus placebo on facial redness.
The prospective, double-blind, randomized pilot study included 33 healthy participants were recruited from the dermatology clinic at the University of California, Davis and nearby community from 2016 to 2017 receive one of three interventions (placebo, turmeric or polyherbal combination tablets) and were told to take the intervention tablets by mouth twice daily for 4 weeks.
According to the results, the polyherbal combination group had a significant decrease in redness of 40% compared to baseline (P = 0.03) compared to that of placebo and turmeric groups with no statistically significant changes in image analysis-based facial redness.
Based on the findings, researchers said, "Polyherbal combination tablet supplementation improved facial redness compared to the turmeric or placebo".
Taken altogether, turmeric processed a high amount of bioactive compound curcumin used alone or combined with other phytochemical may be used for the prevention of skin photo-damage, pending to the confirmation of the larger sample size and multicenter human study.
Intake of turmeric in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective Effect of Curcumin Against Acute Ultraviolet B Irradiation-induced Photo-damage by Li H1, Gao A1, Jiang N1, Liu Q1, Liang B1, Li R1, Zhang E1, Li Z1, Zhu H. (PubMed)
(2) Dietary supplementation with turmeric polyherbal formulation decreases facial redness: a randomized double-blind controlled pilot study by Vaughn AR1, Pourang A2, Clark AK2, Burney W2, Sivamani RK. (PubMed)
(3) Photodamage and skin cancer among paraquat workers by Jee SH1, Kuo HW, Su WP, Chang CH, Sun CC, Wang JD. (PubMed)
Tuesday, April 14, 2020
Cinnamon: The Wholefood Medicine May Process Anti Cervical Cancer Potency, Studies Found
Cinnamon may be the best wholefood medicine for the prevention, management, and treatment of cervical cancer, some scientists suggested.
Cervical cancer is a chronic and medical condition characterized by irregular and disorder cells growth in the cervical tissue. In the beginning, cancer starts in the cell of the cervical lining. After completely colonizing the cervix, malignant cells may travel a distance away through lymph and blood to infect other healthy tissue and organs.
According to the statistic, every year approximately, over 13,000 women in the United States are diagnosed with invasive cervical cancer.
Although the incidence rates for the disease dropped by 50% between 1975 and 2014 due to an increase in screening, cervical cancer still causes over 4,170 deaths this year.
The 5 years survival rate for women diagnosed in the early stage of invasive cervical cancer is 92%. However, in the advanced stage, when cervical cancer has spread to a distant part of the body, the 5-year survival rate is 17%.
The exact causes of cervical cancer are unknown, However, infected by human papillomavirus (HPV) infection due to having sex with men who carry the virus is a major cause of the disease.
Furthermore, women who have many sexual partners, are smoking, use birth control pills (oral contraceptives) for the long-term and engaging in early sexual contact are associated with the increased risk of cervical cancer.
Women, in the early stage of cervical cancer, may not experience any symptoms. If you are having persistent symptoms of abnormal vaginal bleeding, increased vaginal discharge, bleeding after menopause and severe pain during sex and pelvic pain, please check with your doctor to rule out the possibility of cervical cancer.
Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the family Lauraceae.
The spicy herb has been used in herbal and traditional medicine as an anti-fungal and bacteria level, to improve the reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
According to the Manipal University, Eugenol, a potential chemopreventive agent, one of the components of cinnamon possesses antiseptic, analgesic, antibacterial, and anticancer properties in the expression of apoptosis and inflammation against cervical cancer cell lines.
In SiHa cancer cell line, established from cancerous tissues of the cervix uteri, methanol extracts of Gymnema sylvestre (GS) leave and Cinnamomum zeylanicum (CZ) bark exhibited dose-dependent cytotoxicity in inducing apoptosis.
Other researchers suggested that the effects of cinnamon against tumor activity, particularly in cervical cancer cell line SiHa may be the result in the reduced number of colonies, the risk of migration potential through down-regulated normal physiological processes.
Dr. Kwon HK, the lead researcher at the Gwangju Institute of Science and Technology, insisted, Cinnamomum cassia bark,.. containing several active components such as essential oils, expressed anti-tumor effect via enhanced pro-apoptotic and inhibited pro-inflammatory activities, in vitro, and in vivo mouse melanoma model.
In fact, the potential anti-tumor effects of cinnamon may be due to the activities that suppress the cancer progression by increasing the levels of cytolytic molecules and functioning.
Although the whole herb medicine may be a potential agent for reduced risk and treatment of cervical cancer, oral use of cinnamon should be taken with care and only prescribed by a herbalist.
Additional data collection on large example size and multi-centers studies performed with human consumption of the whole food cinnamon during the course of the disease will be necessary to complete the picture of the spicy herb anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells by Hussain A1, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(PubMed)
(2) Biomolecule-loaded chitosan nanoparticles induce apoptosis and molecular changes in cancer cell line (SiHa) by Sujima Anbu A1, Velmurugan P2, Lee JH3, Oh BT4, Venkatachalam P5. (PubMed)
(3) Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential by Koppikar SJ1, Choudhari AS, Suryavanshi SA, Kumari S, Chattopadhyay S, Kaul-Ghanekar R.(PubMed)
(4) Cinnamon extract induces tumor cell death through inhibition of NF-kappaB and AP1 by Kwon HK1, Hwang JS, So JS, Lee CG, Sahoo A, Ryu JH, Jeon WK, Ko BS, Im CR, Lee SH, Park ZY, Im SH. (PubMed)
(5) Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells by Kwon HK1, Jeon WK, Hwang JS, Lee CG, So JS, Park JA, Ko BS, Im SH.(PubMed)
Cervical cancer is a chronic and medical condition characterized by irregular and disorder cells growth in the cervical tissue. In the beginning, cancer starts in the cell of the cervical lining. After completely colonizing the cervix, malignant cells may travel a distance away through lymph and blood to infect other healthy tissue and organs.
According to the statistic, every year approximately, over 13,000 women in the United States are diagnosed with invasive cervical cancer.
Although the incidence rates for the disease dropped by 50% between 1975 and 2014 due to an increase in screening, cervical cancer still causes over 4,170 deaths this year.
The 5 years survival rate for women diagnosed in the early stage of invasive cervical cancer is 92%. However, in the advanced stage, when cervical cancer has spread to a distant part of the body, the 5-year survival rate is 17%.
The exact causes of cervical cancer are unknown, However, infected by human papillomavirus (HPV) infection due to having sex with men who carry the virus is a major cause of the disease.
Furthermore, women who have many sexual partners, are smoking, use birth control pills (oral contraceptives) for the long-term and engaging in early sexual contact are associated with the increased risk of cervical cancer.
Women, in the early stage of cervical cancer, may not experience any symptoms. If you are having persistent symptoms of abnormal vaginal bleeding, increased vaginal discharge, bleeding after menopause and severe pain during sex and pelvic pain, please check with your doctor to rule out the possibility of cervical cancer.
Cinnamon is a spice derived from the inner bark of a tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the family Lauraceae.
The spicy herb has been used in herbal and traditional medicine as an anti-fungal and bacteria level, to improve the reproductive organ, prevent flatulence and intestinal cramping, and to treat indigestion, diarrhea, bad breath, headache, migraine, etc.
According to the Manipal University, Eugenol, a potential chemopreventive agent, one of the components of cinnamon possesses antiseptic, analgesic, antibacterial, and anticancer properties in the expression of apoptosis and inflammation against cervical cancer cell lines.
In SiHa cancer cell line, established from cancerous tissues of the cervix uteri, methanol extracts of Gymnema sylvestre (GS) leave and Cinnamomum zeylanicum (CZ) bark exhibited dose-dependent cytotoxicity in inducing apoptosis.
Other researchers suggested that the effects of cinnamon against tumor activity, particularly in cervical cancer cell line SiHa may be the result in the reduced number of colonies, the risk of migration potential through down-regulated normal physiological processes.
Dr. Kwon HK, the lead researcher at the Gwangju Institute of Science and Technology, insisted, Cinnamomum cassia bark,.. containing several active components such as essential oils, expressed anti-tumor effect via enhanced pro-apoptotic and inhibited pro-inflammatory activities, in vitro, and in vivo mouse melanoma model.
In fact, the potential anti-tumor effects of cinnamon may be due to the activities that suppress the cancer progression by increasing the levels of cytolytic molecules and functioning.
Although the whole herb medicine may be a potential agent for reduced risk and treatment of cervical cancer, oral use of cinnamon should be taken with care and only prescribed by a herbalist.
Additional data collection on large example size and multi-centers studies performed with human consumption of the whole food cinnamon during the course of the disease will be necessary to complete the picture of the spicy herb anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells by Hussain A1, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(PubMed)
(2) Biomolecule-loaded chitosan nanoparticles induce apoptosis and molecular changes in cancer cell line (SiHa) by Sujima Anbu A1, Velmurugan P2, Lee JH3, Oh BT4, Venkatachalam P5. (PubMed)
(3) Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential by Koppikar SJ1, Choudhari AS, Suryavanshi SA, Kumari S, Chattopadhyay S, Kaul-Ghanekar R.(PubMed)
(4) Cinnamon extract induces tumor cell death through inhibition of NF-kappaB and AP1 by Kwon HK1, Hwang JS, So JS, Lee CG, Sahoo A, Ryu JH, Jeon WK, Ko BS, Im CR, Lee SH, Park ZY, Im SH. (PubMed)
(5) Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells by Kwon HK1, Jeon WK, Hwang JS, Lee CG, So JS, Park JA, Ko BS, Im SH.(PubMed)
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