Most Common Diseases of elder: Respiratory Disease: Asthma - The Preventive do and do not’s list

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                    The Preventive do and do not’s list 

1. Breast feeding
Breast feeding is considered to have a protective effect against asthma in children and prolonged breastfeeding was shown to reduce the risk of allergic and respiratory diseases, according to the study by the Dept. of Medical Statistics & Epidemiology, Hamad Medical Corporation, exclusive breast-feeding prevents development of allergic diseases in children. The main factors associated with breastfeeding for allergic diseases were being the first baby, maternal history of asthma, and parental history of allergic rhinitis. The study findings opens a big avenue for interventional role of breastfeeding(49). But longer duration of breastfeeding and later introduction of solid foods did not prevent the onset of asthma, eczema or atopy by age 5 years(50).
2. Lose weight if you are Obese
Asthma is more prevalent in obese compared with normal weight subjects. According to study,
asthma in the obese patient might be more responsive to leukotriene modifiers, orchestrated by leptin and/or adiponectin derived from adipose tissue, than to inhaled corticosteroids, possibly reflecting differences in the underlying airway inflammation in obese vs. non-obese asthmatics.In conclusion, overweight and obesity is associated with poorer asthma control and, very importantly, overall poorer response to asthma therapy compared with normal weight individuals(51).
3. Prevention of occupational asthma
Prevention of occupational asthma related to a work-sensitizing agent ideally would be achieved by avoidance of exposures that cause immunologic sensitization and subsequent asthma.
Education measures for workers to understand the meaning of work-related respiratory symptoms and appropriate workplace safety measures have not been formally evaluated but may also be expected to enhance protective measures and lead to earlier diagnosis, according to the study by Toronto Western Hospital(52).
4. Quit smoking and avoid second smoke
As smoking is considered as one of the major cause of asthma and second hand smoke can cause asthma to children and adult if exposing to a prolonged period of time.
5. Enhancing your immune system to prevent viral infection causes of asthma
6. Avoid asthma triggering allergens if you are diagnosed with allergens cause of asthma

7. Traditional Mediterranean diet
In a cross-sectional survey of 690 children aged 7-18 years in rural Crete, whose parents completed a questionnaire on their child’s respiratory and allergic symptoms and a 58-item food frequency questionnaire,researchers at the University of Crete found that a beneficial effect of commonly consumed fruits, vegetables and nuts, and of a high adherence to a traditional Mediterranean diet during childhood on symptoms of asthma and rhinitis. Diet may explain the relative lack of allergic symptoms in this population(53).
8. Etc.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

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Holistic System In Existence That Will Show You How To
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Back to General health http://kylejnorton.blogspot.ca/p/general-health.htmlSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/9643741
(50) http://www.ncbi.nlm.nih.gov/pubmed/17456214
(51) http://www.ncbi.nlm.nih.gov/pubmed/23258582
(52) http://www.ncbi.nlm.nih.gov/pubmed/20424999
(53) http://www.ncbi.nlm.nih.gov/pubmed/17412780

The Fabulous and Neverfailed smoothies of Green Tea, Avocado and Blueberry for WeightLoss

Kyle J. Norton(Scholar, Master of Nutrients) All right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for people with high risk weight gain and over weight
Yield: 2 serving (about 8 ounce each)
1 1/4 cups blueberry
1/4  cup acocado
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

31% of American adult are obese.  According to the recent statistic, 71% of American are over weight of that have been found to induced chronic illness, including diabetes, heart diseases, .......The prevalence of over weight and obesity may be resulted of typical American diet with high in saturated and trans fat and less consumption of fruits and vegetable.

Recent study suggested that drinking smoothies with ingredients of green tea(1), avocado(5) and blueberry(7) may induce weight loss in overweight and obese people.

Obesity is defined as a medical condition of excess body fat has accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

Epidemiological studies, linking green tea for reduced risk and treatment of overweight and obesity have drawn on hugh interest in scientific community, probably due to its catechins or an epigallocatechin gallate (EGCG)-caffeine mixture effects on weight loss and weight loss maintaining in either over weight and obese person(1).

According to the Maastricht University, intake of high and low caffeine green tea supplementation was associated with weight loss through thermogenesis and fat oxidation and with suppressed leptin in over weight and obese women(2).

In support of the above claim, Dr. Chen IJ and colleagues at the joint study lead by Taiwan International Traditional Chinese Medicine Training Center, said," 12 weeks of treatment with high-dose green tea extract resulted in significant weight loss, reduced waist circumference" and " The antiobestic mechanism of high-dose green tea extract might be associated in part with ghrelin secretion inhibition, leading to increased adiponectin levels"(3).

In fact, green tea has been used in native and traditional herbal history for treatment of obesity, but it is necessary to study more to determine the effectiveness and safety of medicinal plants and herbal extracts as well as pharmaceutically active ingredients, the joint study lead by the Urmia University of Medical Sciences concluded(4).

Avocados are a commercially valuable fruit and are cultivated in tropical climates throughout the world, it is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae.

In a Sixty-one free-living volunteers (13 men and 48 women), with body mass index of 32 +/- 3.9 kg/m(2) (mean +/- standard deviation) participated in this randomized, controlled, parallel study, avocado intake decreased significantly body mass, body mass index, and percentage of body fat, without effectingserum lipid concentrations, plasma fibrinogen, arterial compliance, and systolic and diastolic blood pressures(5).

Dr Walker KZ and Dr. O'Dea K. said," Using a 'modified fat' (MF) diet enriched with monounsaturated fat (MUFA), body weight may be lost either by calorie counting, or by allowing ad libitum food intake with careful food selection"(6)

In support of avocado used for decrease weight in overweight and obese subjects, the Bharathi Women's College, Broadway study showed that avocado fruit extract has profound influence on leptin activity, which controls satiety and hunger to regulate the food intake, via its modulating effect on endogenous fat synthesis and adiponectin formation through the transcription factor FGF21(7).

Blueberry, a flower plant, belong to the family Eriaceae and native to Northern America may be the potential fruits used for reduced weight in over weight and obese person(8). As the Blueberry Leaf Extract (BBLE) significantly suppressed the over weight gain, decreased the TG level in the liver and inhibited leptin secretion and also improved insulin resistance in the HFD-fed C57BL/6 mice(8).

The Gyeongsang National University study also found that blueberry peel extracts (BPE) exhibited anti-obesity effect and mechanism through inhibiting adipogenesis in 3T3-L1 cells in synthesis and accumulation of triglycerides (9).

Dr. Wu T and the research team lead by the Zhejiang University, said," blueberry and mulberry juice may help counteract obesity" in the study of 4week-old C57BL/6 mice were fed a high-fat diet (HFD) with or without blueberry and mulberry juice for 12 weeks(10).

Taking all together, smoothie of green tea, avocado and blueberry may be a potent drink for reduced weight and treatment of overweight and obese subjects
People who are at increased risk of overweight due to family history, gene mutation, .....should drink at least one serving daily and overweight and obese people should drink the smoothie as much as they can depending to digestive toleration.
Change life style and diet pattern are also recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References

(1) The effects of green tea on weight loss and weight maintenance: a meta-analysis by Hursel R1, Viechtbauer W, Westerterp-Plantenga MS.(PubMed)

(2) Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation by Westerterp-Plantenga MS1, Lejeune MP, Kovacs EM.(PubMed)

(3) Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial by Chen IJ1, Liu CY1, Chiu JP1, Hsu CH2.(PubMed)

(4) Obesity Phytotherapy: Review of Native Herbs Used in Traditional Medicine for Obesity by Bahmani M1, Eftekhari Z2, Saki K3, Fazeli-Moghadam E4, Jelodari M5, Rafieian-Kopaei M6.(PubMed)

(5) Substitution of high monounsaturated fatty acid avocado for mixed dietary fats during an energy-restricted diet: effects on weight loss, serum lipids, fibrinogen, and vascular function by Pieterse Z1, Jerling JC, Oosthuizen W, Kruger HS, Hanekom SM, Smuts CM, Schutte AE.(PubMed)

(6) Is a low fat diet the optimal way to cut energy intake over the long-term in overweight people? by Walker KZ1, O'Dea K.(PubMed)

(7) The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin--A biochemical study in rats subjected to experimental hyperlipidemia and obesity by Monika P1, Geetha A2.(PubMed)

(8) Antioxidative Activity of Blueberry Leaf Extract Prevents High-fat Diet-induced Obesity in C57BL/6 Mice by Lee IC1, Kim DY2, Choi BY2.(PubMed)

(9) Blueberry peel extracts inhibit adipogenesis in 3T3-L1 cells and reduce high-fat diet-induced obesity by Song Y1, Park HJ, Kang SN, Jang SH, Lee SJ, Ko YG, Kim GS, Cho JH.(PubMed)

(10) Blueberry and mulberry juice prevent obesity development in C57BL/6 mice by Wu T1, Tang Q, Gao Z, Yu Z, Song H, Zheng X, Chen W.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Asthma - The Preventive Diet

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                            The Preventive Diet

1. Apple
Diet high in fruits and vegetables may decrease the risk of chronic diseases. In the study of Apple phytochemicals and their health benefits, found that apples have been found to have very strong antioxidant activity, inhibit cancer cell proliferation, decrease lipid oxidation, and lower cholesterol. Apples contain a variety of phytochemicals, including quercetin, catechin, phloridzin and chlorogenic acid, all of which are strong antioxidants. The phytochemical composition of apples varies greatly between different varieties of apples, and there are also small changes in phytochemicals during the maturation and ripening of the fruit(62).

2. Artichoke and Strawberries
Gallic acid (Strawberries) and caffeic acids (Artichoke) are reported to modulate allergic reactions via unknown mode(s) of action. In the stufy to evaluate whether both phenolic acids share a common mode of action with the two asthma drugs, suggest that certain anti-inflammatory phytochemicals including gallic acid and wedelolactone may modulate inflammatory allergic action via their agonism at GPR35. GPR35 may represent a target for the treatment of allergic disorders including asthma(63).
3. Flax and Sunflower seeds

Omega 3 fatty acid is types of phytochemical found abundantly in flax and sunflower seeds
In the study to assess the relation between observed levels of omega-3 fatty acids in plasma and symptoms of asthma and atopy in children at 18 months of age, showed that omega-3 fatty acid levels were expressed in quintiles of exposure ‘as treated’ without reference to treatment group allocation. Wheeze ever, doctor visits for wheeze, bronchodilator use and nocturnal coughing were significantly reduced in children in the higher exposure quintiles. Serum IgE was reduced in the highest quintile but not significantly so. There was no difference in diagnosed asthma or atopy between the exposure quintiles. Although wheeze at this age may not be a good indicator of asthma in later childhood, it is encouraging that some symptoms have been reduced in children with high omega-3 fatty acid concentrations in plasma(64).

4. Tomato
Lycopene, a phytochemical found abundantly in tomato. In the study to investigate the effects of lycopene, on allergic inflammation, in a mouse model of AAD. BALB/c mice receiving lycopene supplement or control were intraperitoneally sensitised and intranasally challenged with ovalbumin (OVA) to induce AAD, found that supplementation with lycopene reduces allergic inflammation both in the lungs and systemically, by decreasing Th2 cytokine responses. Thus, lycopene supplementation may have a protective effect against asthma(65).

5. Peaches, organic orange juice
Peach contains high amount of vitamin C which may be used to prevent and treat asthma.
In this double blind clinical trial study to evaluated 60 patients with chronic stable asthma. The patients were divided into two groups (A and B) including 30 patients in each group. group A received 1000 mg vitamin C daily and group B received placebo, found that The mean (±SD) leukocyte vitamin C level in group A at the baseline and after one month treatment with 1000 mg/day vitamin C, were 0.0903 (±0.0787) µg/108 leukocytes and 0.1400 (±0.0953) µg/108 leukocytes respectively (P<0.05). The mean (±SD) leukocyte vitamin C level in group B at the baseline and after one month administration of placebo, were 0.0867 (±0.0629) µg/108 leukocytes and 0.0805(±0.0736) µg/108 leukocytes respectively. The leukocyte vitamin C level in group A was higher than those of group B after one month treatment with vitamin C and placebo and the difference was statistically significant (P<0.05)(66)
6. Etc.

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/9643741
(62) http://www.ncbi.nlm.nih.gov/pubmed/15140261
(63) http://www.ncbi.nlm.nih.gov/pubmed/22488351
(64) http://www.ncbi.nlm.nih.gov/pubmed/15610365
(65) http://www.ncbi.nlm.nih.gov/pubmed/20392623
(66) http://www.ncbi.nlm.nih.gov/pubmed/22592572

The Fabulopus and Tasty Smoothie of Blueberry and Cooked Tomato for Reduced Risk and Treatment of Oxidative stress

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for women with high risk of Oxidative stress and treatment of Oxidative stress

Yield: 2 serving (about 8 ounce each)
1 cup blueberry
1/2 cup cooked tomato
1 cup rice milk

1. Place the all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately


The dream of finding the natural ingredient for prevention and treatment of oxidative stress without adverse effects in replacement of conventional medicine has not been abated. Some ingredients have to discard due to it can achieve the same potent results in human trials.
In fact, oxidative stress is considered as one of most common factor for the development of several chronic diseases, such as diabetes, cancer, cardiovascular and neurodegenerative diseases. Antioxidants, found mostly in fruits and vegetables play an important role in inhibition of the reactive oxygen species ROS through its function as a molecule that inhibits the oxidation of other molecules.

Recent studies suggested that blue berry, tomato may consist a therapeutic value for reduced risk and treatment of oxidative stress in induction of diseases and syndromes.

Blueberry is a flower plant, belongings to the family Eriaceae and native to Northern America. The edible fruit has now been cultivated all over the world in suitable climate for commercial profits due to recent discovery of its health benefits, particular in oxidative stress effect.According to the joint study lead by the Istanbul University, Blueberries (BB) containing high antioxidant capacity, exhibited dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities in decreased the expression of oxidative stress causes of hepatic cirrhosis and preneoplastic lesions(1).

Other study in the evaluation of its antioxidants known as anthocyanins expressed the possible effect of blueberry in attenuated oxidative stress and inflammatory cytokines, through activation of immune natural killer cell count in 6 weeks of administration(2).

The joint study by China Agricultural University, in support of the effects of anthocyanins against oxidative stress suggested that the antioxidant inhibited reactive oxygen species (ROS) formation and prevented the successive events associated with the mitochondrial damage and dysfunction, including recovered activities of electron transport chain, through intervention of Acrylamide (AA) toxicity incuded by heat(3). Furthermore, daily intake of blueberry (BB) supplementations also found to decrease oxidative stress signalling, increase neurogenesis, and increase signals involved in learning and memory through increased hippocampal neurogenesis related brain function and expression of insulin-like growth factor 1 in enhanced immunity(4).

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house.

In Human Mesenchymal Stem Cells, lycopene found in cooked tomato significantly increased manganese superoxide dismutase (MnSOD) expression and decreased cellular ROS levels via the PI3K-Akt pathway in regulating cell cycle(5).

Dr. Lei X and colleagues in the joint study of a total of total of 60 male C57BL/6 mice, lead by the Shanxi Medical University, indicated that lycopene exhibited anti oxidative stress through improved the neurological score and attenuated neuronal apoptosis in the BCCAO mice in activation of metabolic and anti-oxidant defenses(6).

In acute cholestasis, the phytochemical also expressed the hepato protective role in diseases related to oxidative stress through inhibition of pathogenesis of cholestasis(7).

Dr Kim M and Dr., Kim H at the Yonsei University, in the investigation of gastric carcinogenesis said:" Risk factors of gastric carcinogenesis include oxidative stress,..... " and " lycopene, one of the naturally occurring carotenoids, has unique structural and chemical features that contributes to a potent antioxidant activity(8).

Taking altogether, Smoothie of Blueberry and Cooked Tomato may be effective for reduced risk of oxidative stress and its complications. People with high risk of oxidative stress, such as smoking,... should drink the smoothie at least one daily and people with oxidative stress induced chronic illness should drink as much as they can, depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References

(1) Blueberry treatment attenuated cirrhotic and preneoplastic lesions and oxidative stress in the liver of diethylnitrosamine-treated rats by Bingül İ1, Başaran-Küçükgergin C1, Aydın AF1, Soluk-Tekkeşin M2, Olgaç V2, Doğru-Abbasoğlu S1, Uysal M3.(PubMed)
(2) Effect of blueberry ingestion on natural killer cell counts, oxidative stress, and inflammation prior to and after 2.5 h of running by McAnulty LS1, Nieman DC, Dumke CL, Shooter LA, Henson DA, Utter AC, Milne G, McAnulty SR.(PubMed)
(3) The chemoprotection of a blueberry anthocyanin extract against the acrylamide-induced oxidative stress in mitochondria: unequivocal evidence in mice liver by Zhao M1, Wang P, Zhu Y, Liu X, Hu X, Chen F.(PubMed)
(4) The beneficial effects of berries on cognition, motor behaviour and neuronal function in ageing by Shukitt-Hale B1, Bielinski DF1, Lau FC1, Willis LM1, Carey AN1, Joseph JA1.(PubMed)
(5) Pretreatment with Lycopene Attenuates Oxidative Stress-Induced Apoptosis in Human Mesenchymal Stem Cells by Kim JY1, Lee JS2, Han YS3, Lee JH1, Bae I2, Yoon YM3, Kwon SM1, Lee SH4.(PubMed)
(6) Neuroprotective effects of lycopene pretreatment on transient global cerebral ischemia‑reperfusion in rats: The role of the Nrf2/HO‑1 signaling pathway by Lei X1, Lei L2, Zhang Z1, Cheng Y1.(PubMed)

(7) Hepatoprotective and antioxidant effects of lycopene in acute cholestasis by Tokaç M, Aydin S, Taner G, Özkardeş AB, Yavuz Taşlipinar M, Doğan M, Dündar HZ, Kiliç M, Başaran AA, Başaran AN.(PubMed)
(8) Anticancer Effect of Lycopene in Gastric Carcinogenesis by Kim MJ1, Kim H1.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Asthma - The Misdiagnosis

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma

Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                                                                 Misdiagnosis

According to the study by Scripps Memorial Hospital, two common reasons asthmatics fail standard therapy are incorrect diagnosis and failure to recognize underlying contributing factors(41), including 1. Vocal cord dysfunction
Vocal cord dysfunction (VCD) is a respiratory disorder characterized by paradoxical closure of the vocal cords during the respiratory cycle leading to obstructive airway symptoms. Misdiagnosis of VCD as asthma leads to inappropriate use of systemic steroids with its adverse effects, frequent emergency department visits, hospitalization, and, rarely, intubation and tracheostomy(42).

2. Respiratory bronchiolitis interstitial lung disease
Respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) is a type of idiopathic interstitial pneumonia (IIP) found to be associated with smokers. Many patients with interstitial lung disease have their chronic cough mistakenly attributed to that condition when, in fact, the cough is due to more common disorders such as asthma, upper airway cough syndrome (previously referred to as postnasal drip syndrome), or gastroesophageal reflux disease(43).

3. Chronic obstructive pulmonary disease (COPD)
According to the study by National Jewish Medical and Research Center, despite the availability of consensus guideline diagnostic recommendations, diagnostic confusion between COPD and asthma appears common. Increased awareness of the differences between the two conditions is needed to promote optimal patient management and treatment(44).

4. Psychogenic cough
Psychogenic cough and its relationship to asthma and other asthma-like illnesses is complex since distinct maladies with similar features may coexist individually or in combination in any given patient. While chronic cough may occur as a sole presenting manifestation of bronchial asthma in all age groups, recent findings suggest that most children with persistent cough without other respiratory symptoms do not have asthma, according to the study by Ohio University(45).

5. Tracheobronchomalacia

There is a report of 62-year-old woman, diagnosed as bronchial asthma 3 years previously, was admitted due to acute severe dyspnea. Physical examination revealed saddle nose, flare/swelling of the ear auricles, and stridor. Computed tomography demonstrated thickening of tracheal/bronchial walls and stenosis of the lumen that deteriorated on expiration, suggesting tracheobronchomalacia(46).

6. Tracheal schwannoma
There is a report of a case of tracheal schwannoma in a female patient who presented with breathlessness and wheeze, and she was being treated for asthma(47).

7. Exercise-induced bronchoconstriction
A high proportion of English professional soccer players medicated for asthma/EIB (a third with reliever therapy only) do not present reversible airway obstruction or airway hyperresponsiveness to indirect stimuli, according to the study by University of Northumbria(48).
8. Etc.
Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/9643741
(41) http://www.ncbi.nlm.nih.gov/pubmed/22128653
(42) http://www.ncbi.nlm.nih.gov/pubmed/11140406
(43) http://www.ncbi.nlm.nih.gov/pubmed/16093815
(44) http://www.ncbi.nlm.nih.gov/pubmed/16448970
(45) http://www.ncbi.nlm.nih.gov/pubmed/17613629
(46) http://www.ncbi.nlm.nih.gov/pubmed/22790144
(47) http://www.ncbi.nlm.nih.gov/pubmed/22584990
(48) http://www.ncbi.nlm.nih.gov/pubmed/22175650

The Tasty Smoothie of Strawberry, broccoli and Green Tea for reducing risk and treatment of Colorectal Cancer

Kyle J. Norton(Scholar), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of colorectal cancer

Yield: 2 serving (about 8 ounce each)
1 cup of strawberry

1/2 cup broccoli
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of colorectal cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Colorectal cancer is relatively very common and slowly growing and progress cancer and in predictable way. It is the third most commonly diagnosed cancer in developed countries, including US and Canada.

Fruits rich in bioactive phytochemicals including several classes of phenolic compounds such as flavonoids (anthocyanins, flavonols and flavanols) and phenolic acids (hydroxybenzoic and hydroxycinnamic acids) are associated to lower risk of cancer, including bowel cancer(1)(2).

Strawberries is a genius of Fragaria × ananassa belongings to the family Roseaceae. The fruits have been grown all over the world in suitable climate for commercial profits and health benefits. Recent study by the Università Politecnica delle Marche, suggested that strawberry extracts expressed strongly anti oxidant effects and the capacity of promoting the action of antioxidant enzymes in protection against free radicals induced gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease(4).

According to the University of California, berry extracts, particular strawberry containing major classes of berry phenolics expressed potential ability in inhibition of the growth of human colon (HT-29, HCT116) cancers through anti cell proliferation and modulate cellular proliferation and apoptosis of COX-2 expressing(3).

In support to the above claim, Dr. Wu QK and the research team at the University of Kuopio, berry extracts,(including strawberry) containing different phenolic profiles on cell viability and expression of markers of cell proliferation and apoptosis in human colon cancer HT-29 cells(5).

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. It has large flower heads, usually green in color and the mass of flower heads is surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

Isothiocyanates (ITCs) found in broccoli induced apoptosis in human colon cancer cell line SW480, through expression in some unkown potential pathways(6).

Sulforaphane, another natural product commonly found in broccoli, inhibited HCT116 human colon cancer cells angiogenesis and its progression through attenuating the expression of angiogenesis of tumors and mammalian development(HIF-1α) and migration and proliferation of endothelial cells(VEGF)(7).

Dr. Lippmann D and colleagues at the German Institute of Human Nutrition Potsdam-Rehbruecke said," High consumption of Brassica vegetables is considered to prevent especially colon carcinogenesis" and "GSLs(glucosinolates) can act anti-inflammatory and anti-carcinogenic but both effects depend on the specific amount and pattern of GSLs within a vegetable"(8).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

According to the Saga University, drinking 10 Japanese-size cups of green tea daily, supplemented with tablets of green tea extract (GTE), reduced the recurrence of colorectal cancer by 51.6% in patients after polypectomy(11) and an average of tumor volume by 70.3%(11). 

In a cohort of 69,710 Chinese women aged 40 to 70 years, drink tea regularly at both the baseline and follow-up surveys are associated to reduced risk of colon and rectal  cancer(9). According to the Shanghai Men's Health Study, regular consumption of green tea may reduce colorectal cancer risk among non-smokers but not smokers(10).

Dr. Núñez-Sánchez MA and colleagues at the Department of Food Science and Technology, CEBAS-CSIC, Murcia, Spain said," Preclinical studies using in vitro (cell lines) and animal models of CRC have reported anticancer effects for dietary phenolics through the regulation of different markers and signaling pathways" but " Overall, the clinical evidence of dietary phenolics against CRC is still weak and the amounts needed to exert some effects largely exceed common dietary doses"(12)

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.

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References

(1) Mechanisms underlying the anti-proliferative effects of berry components in in vitro models of colon cancer by Brown EM1, Gill CI, McDougall GJ, Stewart D(PubMed)

(2) Berry phytochemicals, genomic stability and cancer: evidence for chemoprotection at several stages in the carcinogenic process by Duthie SJ1.(PubMed)

(3) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro by Seeram NP1, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)

(4) Strawberry polyphenols attenuate ethanol-induced gastric lesions in rats by activation of antioxidant enzymes and attenuation of MDA increase by Alvarez-Suarez JM1, Dekanski D, Ristić S, Radonjić NV, Petronijević ND, Giampieri F, Astolfi P, González-Paramás AM, Santos-Buelga C, Tulipani S, Quiles JL,Mezzetti B, Battino M.(PubMed)

(5) Berry phenolic extracts modulate the expression of p21(WAF1) and Bax but not Bcl-2 in HT-29 colon cancer cells by Wu QK1, Koponen JM, Mykkänen HM, Törrönen AR.(PubMed)

(6) Isothiocyanates from Broccolini seeds induce apoptosis in human colon cancer cells: proteomic and bioinformatic analyses by Yang Y1, Yan H, Li Y, Yang ST, Zhang X.(PubMed)

(7) Sulforaphane inhibits hypoxia-induced HIF-1α and VEGF expression and migration of human colon cancer cells by Kim DH1, Sung B1, Kang YJ1, Hwang SY1, Kim MJ1, Yoon JH1, Im E1, Kim ND1.(PubMed)

(8) Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancerdifferently by Lippmann D1, Lehmann C, Florian S, Barknowitz G, Haack M, Mewis I, Wiesner M, Schreiner M, Glatt H, Brigelius-Flohé R, Kipp AP.(PubMed)

(9) Prospective cohort study of green tea consumption and colorectal cancer risk in women by Yang G1, Shu XO, Li H, Chow WH, Ji BT, Zhang X, Gao YT, Zheng W.(PubMed)

(10) Green tea consumption and colorectal cancer risk: a report from the Shanghai Men's Health Study by Yang G1, Zheng W, Xiang YB, Gao J, Li HL, Zhang X, Gao YT, Shu XO.(PubMed)

(11) Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds by Fujiki H1, Sueoka E, Watanabe T, Suganuma M.(PubMed)

(12) Dietary phenolics against colorectal cancer--From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs by Núñez-Sánchez MA1, González-Sarrías A1, Romo-Vaquero M1, García-Villalba R1, Selma MV1, Tomás-Barberán FA1, García-Conesa MT1, Espín JC1.(PubMed)

Most Common Diseases of elder: Respiratory Disease: Asthma - The Complications

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                                  Asthma


Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                                     The Complications

1. Quality of life
In a cross-sectional study explored the relationships among family ritual meaning, cohesion, conflict, and health-related quality of life (both specific to chronic health conditions and in general), and the emotional and behavioral problems reported by youths with asthma, conducted by Faculty of Psychology and Educational Sciences, University of Coimbra, showed that stronger family ritual meaning predicted a more positive family environment (i.e., higher cohesion levels and lower conflict levels), better health-related quality of life, and fewer emotional and behavior problems in youths. Furthermore, family cohesion and conflict mediated the links between family ritual meaning and health-related quality of life, and emotional and behavioral problems(34). In 2007–08, people with asthma were more likely to have taken days off work, school or study in the last 12 months due to a long term condition than people without asthma (although these days off were not necessarily due to asthma). People with asthma rate their health worse than people without the condition, according to the data ofAIHW(35).

2. Corticoid-associated complications
In the stduy to evaluate the frequency and type of side effects and complications of long-term corticosteroid therapy in the elderly, showed that infectious complications were found in 26 cases (39.3%), 11 cases (16.7%) of iatrogenic diabetes, arterial hypertension in 9 cases (13%), skeletal complications in both cases,psychiatric complications in two cases, ophthalmologic complications in one case(36).

3. Subcutaneous and mediastinal emphysema
There is a report of a case of a 21-year-old man admitted with asthma attack complicated by subcutaneous and mediastinal emphysema. Chest tomography confirmed the mediastinal emphysema and also revealed the epidural emphysema within the vertebral canal(37).

4. Pneumomediastinum
There is a report of a 17-year-old girl with severe asthma exacerbations. On admission to the intensive care unit, she manifested expiratory dyspnea, cyanosis, and an unproductive cough. Her chest x-rays showed extensive pneumomediastinum (PM), mild subcutaneous emphysema at the right anterior triangle of the neck, and right upper-lobe atelectasis(38).

5. Respiratory complicationsChildren with asthma are at increased risk for obstructive breathing during sleep. Adenotonsillectomy, the treatment of choice for obstructive breathing during sleep, is associated with significant postoperative respiratory morbidity. According to the study by Cincinnati Children’s Hospital, Cincinnati, in children with obstructive breathing during sleep, the presence of asthma is associated with an increased risk of respiratory complications after adenotonsillectomy(39). Other indicated that the frequency of perioperative bronchospasm and laryngospasm was surprisingly low in this cohort of persons with asthma. These complications did not lead to severe respiratory outcomes in most patients. The frequency of complications was increased in older patients and in those with active asthma(40).

6. Potentially (near) fatal asthma (PFA)
Potentially (near) fatal asthma (PFA) defines a subset of patients with asthma who are at increased risk for death from their disease. According to the study by the Northwestern University Feinberg School of Medicine, a diagnosis of PFA is made when any one of the following are present: (1) history of endotracheal intubation from asthma, (2) acute respiratory acidosis (pH < 7.35) or respiratory failure from acute severe asthma, (3) two or more episodes of acute pneumothorax or pneumomediastinumfrom asthma, (4) two or more episodes of acute severe asthma despite the use of long-term oral corticosteroids and other antiasthma medications.
In the UK in 2005, over 1300 people died from asthma, and on average one person dies from asthma every seven hours.
7. Etc.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca p/general-health.html

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/9643741
(35) http://www.aihw.gov.au/asthma-quality-of-life/
(36) http://www.ncbi.nlm.nih.gov/pubmed/23197053
(37) http://www.ncbi.nlm.nih.gov/pubmed/23182721
(38) http://www.ncbi.nlm.nih.gov/pubmed/20561891
(39) http://www.ncbi.nlm.nih.gov/pubmed/15945558
(40) http://www.ncbi.nlm.nih.gov/pubmed/8853074