Tuesday, February 2, 2016

The Curable and delicious smoothie of Green Tea, Avocado and Grape for Reduced Risk and Treatment of Contact Dermatitis

Kyle J. Norton(Scholar, Master of Nutrients) All right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The fabulous and tasty smoothie with the power to reduce risk and treatment of stroke through clinical trial, research and studies is a must know to everyone by Kyle J. Norton.

The smoothie for people with high risk of contact dermatitis
Yield: 2 servings (about 8 ounces each)
1 cup grape
1/2 cup avocado
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)


1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Contact dermatitis is an immune reaction induced red, itchy rash against substance that comes into contact with your skin. Green tea extracts used for treatment of inflammation, aging, and cardiometabolic effects may also consisted a therapeutic values in relief the symptoms of allergic contact dermatitis(1).
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects,
green tea now has been cultivated all over the world in suitable climate. Its extracts consisted anti inflammation, aging, and cardiometabolic effects may also consisted a therapeutic values in relief the symptoms of allergic contact dermatitis(1).
The University Hospitals Case Medical Center Clevelandstudy also suggested that chronic topical application of green tea also exhibited the protection against detrimental effects of UV on cutaneous immunity(2) and DNA damage that formed after UV radiation(3).

Avocados are a commercially valuable fruit, cultivated in tropical climates throughout the world. The green-skinned, pear-shaped fruit ripens after harvesting and native to the Caribbean, Mexico, South America and Central America, belonging to the flowering plant family Lauraceae. According to the Universidade Federal do Paraná, topical avocado reduced secretion of PGE(2) in 12-O-tetradecanoylphorbol-13-acetate (TPA)(a potent tumor promoter )-induced keratinocyte( the outermost layer of the skin)(4).
Application of Polyhydroxylated fatty alcohols derived from avocado, according to Polyol Biotech Ltd, Granot Initiative Center, exert UVB protective effect through increasing cell viability, decreasing the secretion of IL-6 and PGE(2), and enhancing DNA repair(5).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc. According to the joint study lead by the Chonnam National University Medical School, ethanol extract of peanut sprouts (EPS) inhibited protective effect against contact dermatitis of mouse skin and compound 48/80-treated HaCaT cells through its anti-inflammatory activity via its anti-oxidant activity(6) as well as its cytoprotective effects against UVB in detoxifying enzymes in human dermal fibroblasts against UVB-irradiated oxidative stress(7).
Dr. Feng LL and the colleagues at the , Nanjing University insisted that, the effectiveness of resveratrol in ameliorated ear swelling in a mouse model of picryl chloride-induced ear contact dermatitis, may be result from preventing the cells from entering S phase and G2/M phase during T cells activation(9).

Taking altogether, people who are at high risk of contact dermatitis due to family history, obesity, ioccupation,,..... should drink at least one serving daily and people with contact dermatitis should drink the smoothie as much as they can, depending to digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

 References(1) Human skin safety test of green tea cell extracts in condition of allergic contact dermatitis by Kim HK1, Choi SY, Chang HK, Baek SY, Chung JO, Rha CS, Kim BJ, Kim MN.(PubMed)
(2) Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin by Camouse MM1, Domingo DS, Swain FR, Conrad EP, Matsui MS, Maes D, Declercq L, Cooper KD, Stevens SR, Baron ED.(PubMed)
(3) Cutaneous photoprotection from ultraviolet injury by green tea polyphenols by Elmets CA1, Singh D, Tubesing K, Matsui M, Katiyar S, Mukhtar H.(PubMed)
(4) Attenuation of experimental TPA-induced dermatitis by acetylenic acetogenins is associated with inhibition of PLA₂ activity by Otuki MF1, Schwob O, Silveira Prudente A, Zaltsman I, Meretski S, Segal J, Yedgar S, Rosenblat G.(PubMed)
(5) Polyhydroxylated fatty alcohols derived from avocado suppress inflammatory response and provide non-sunscreen protection against UV-induced damage in skin cells by Rosenblat G1, Meretski S, Segal J, Tarshis M, Schroeder A, Zanin-Zhorov A, Lion G, Ingber A, Hochberg M.(PubMed)
(6) Ethanol Extract of Peanut Sprout Exhibits a Potent Anti-Inflammatory Activity in Both an Oxazolone-InducedContact Dermatitis Mouse Model and Compound 48/80-Treated HaCaT Cells by Choi DI1, Choi JY1, Kim YJ1, Lee JB1, Kim SO2, Shin HT3, Lee SC1.(PubMed)
(7) Ethanol extract of peanut sprout induces Nrf2 activation and expression of antioxidant and detoxifying enzymes in human dermal fibroblasts: implication for its protection against UVB-irradiated oxidative stress by Choi JY1, Choi DI, Lee JB, Yun SJ, Lee DH, Eun JB, Lee SC.(PubMed)
Posted by at No comments:

Most Common Diseases of elder: Chronic obstructive pulmonary disease (COPD) (Respiratory Disease): The Diet

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                         Respiratory Disease 
Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Chronic obstructive pulmonary disease (COPD))is the third leading cause of death in the United State.

  Types of Chronic obstructive pulmonary disease (COPD)


1. Emphysema, a type of Chronic obstructive pulmonary disease (COPD), is defined as a long term and progressive condition cause of shortness of breath but depending to the stage of lung function as a result of damage to tissues of the air sacs (alveoli) in the lungs. In the study of 63 patients with stable COPD (spirometric GOLD stages 2–4) and 17 age- and comorbidity-matched controls, researchers found that in contrast to asthma, COPD is characterised by elevated concentrations of both BDNF and TGF-beta1 in serum. The stage-dependent association with lung function supports the hypothesis that these platelet mediators may play a role in the pathogenesis of COPD(1). In some cases, but rarely, Emphysema is caused by Alpha-1 antitrypsin deficiency emphysema.

2. Chronic bronchitis
Chronic bronchitis is a chronic inflammation of the lung’s bronchi cause of the increased production of mucus in the lung of that leading to difficult breathing.

                     The Prevention

The Diet

1. Neotropical blueberry and barley leaves
In the study of four flavone C-glycosides, isoorientin (1), orientin (2), vitexin (3), and isovitexin (4), isolated from the neotropical blueberry, using antioxidant activity-guided fractionation, found that he four flavone C-glycosides exhibited inhibitory activity against IL-8 production and MMP-1 expression, with compounds 1, 3, and 4 having the most potent inhibitory activities in both assays at 100 μg/ml(1).
2. Turmeric
Cadmium is a toxic metal present in the environment and its inhalation can lead to pulmonary disease such as lung cancer and chronic obstructive pulmonary disease. These lung diseases are characterized by chronic inflammation. In the study of Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium, researchers found that the natural antioxidant curcumin could prevent both cadmium-induced IL-6 and IL-8 secretion by human airway epithelial cells. In conclusion, curcumin could be used to prevent airway inflammation due to cadmium inhalation(2).
3. Oats, sweet corn and rice
Oats, sweet corn and rice contain measurable amounts of melatonin. In recent studies show that, α, β-unsaturated aldehyde acrolein in CS induces the production of interleukin (IL)-8, which is known to be related to bronchitis, rhinitis, pulmonary fibrosis, and asthma. In addition, lung and pulmonary fibroblasts secrete IL-8, which has a chemotactic effect on leukocytes, and which in turn, play a critical role in lung inflammation. Acrolein-induced IL-8 production was accompanied by increased levels of phosphorylation of Akt and extracellular signal-regulated kinases (ERK1/2) in HPFs, and that melatonin suppressed IL-8 production in HPFs. These results suggest that melatonin suppresses acrolein-induced IL-8 production via ERK1/2 and phosphatidylinositol 3-kinase (PI3K)/Akt signal inhibition in HPFs(3).
4. Grape skin
In the study of the effects of grape skin in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD), showed that alteration of the oxidant-antioxidant balance is important in the pathogenesis of CS-induced ALI and suggests lung protective effects of GSE treatment in the mouse(4).
5. Grape skin, seed and red wine
In the study to investigate the effect of dexamethasone versus resveratrol on the release of COPD-related inflammatory mediators (IL-6, IL-8, GM-CSF and MCP-1) and matrix-metalloprotease-9 (MMP-9) from alveolar macrophages exposed to gram-negative bacterial endotoxin (lipopolysaccharide, LPS), found that resveratrol almost completely reduced the release of all cytokines and MMP-9 without significant differences between the cohorts. Our data provide evidence for a corticosteroid resistance of alveolar macrophage-dependent inflammatory responses induced by gram-negative bacteria in COPD and thus question the utility of corticosteroids in COPD therapy. Instead, resveratrol may prove an alternative(5).
6. Etc.
Posted by at No comments:

The Smoothie of Banana, Avocado and Herbal Ginger Tea for Prevention and Treatment of Hyperemesis gravidarum in Pregnancy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of Hyperemesis gravidarum(Liver disease)

Yield: 2 servings (about 8 ounces each)
1 cup banana
1/2 cup avocado
1 cup herbal ginger tea

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of intrahepatic cholestasis of pregnancy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hyperemesis gravidarum of pregnancy is a medical condition with severe nausea, vomiting, weight loss, and electrolyte disturbance during pregnancy. The prevalence of hyperemesis gravidarum of 
pregnancy, may be associated to the presence of serum levels of neopterin, as a marker for immune system activation, inflammatory markers and oxidative stress(1)(2), particular Vitamin E, E equivalent, vitamin C, carotene and vitamin A levels(3).

Recent studies back by well known institutions proposed, Banana(7), Avocado(7) and Herbal Ginger Tea(4) may be the next generation of natural ingredients for prevention and treatment of hyperemesis gravidarum.

Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc. According to the University of Copenhagen, powdered root of ginger in daily doses of 1 g during 4 day, scored an significantly geater relief of the symptoms hyperemesis gravidarum in comparison to placebo(4).
Dr. Sonkusare S. professor at the Melaka Manipal Medical College, said, "The management of the (hyperemesis gravidarum)condition involves symptomatic treatment along with antiemetic, pyridoxine and thiamine. Important role of alternative therapies like ginger and P6 acupoint stimulation in the treatment of hyperemesis has been identified"(5).
Truly, the search of Medline, Embase, The Cochrane Library, and other important databases up to September 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review) by Festin M, professor at the Philippine General Hospital, suggested, alternative medicine of ginger root may also be effective for reduced risk and treatment of hyperemesis gravidarum when used combination with acupressure; acupuncture; corticosteroids; metoclopramide; ondansetron; prochlorperazine; promethazine; and pyridoxine (vitamin B6)(6).

Pyridoxine, also known as vitamin B6 found abundantly in bananas, and avocados is also found to associate to reduce risk and treatment of  Hyperemesis gravidarum(7).
According to the case of Naval Medical Center, in a double-blind, randomized, controlled trial in which women with nausea and vomiting of pregnancy, showed that the combination of pyridoxine and doxylamine relieved symptoms of nausea and emesis in pregnancy but lesser than those of ondansetron(8).

The effectiveness of Banana, Avocado and Herbal Ginger Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and  treatment of hyperemesis gravidarum with little or no adverse effects.

Women who are at high risk of hyperemesis gravidarumdue to family history, previous pregnancy..... should drink at least one serving daily and women with hyperemesis gravidarumshould drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable

Ovarian Cysts And PCOS Elimination


References
(1) Serum levels of neopterin, inflammatory markers and oxidative stress indicators in hyperemesis gravidarum by Tunc SY1, Agacayak E1, Budak S2, Tunc N3, Icen MS1, Findik FM1, Ekinci A4, Gul T1.(PubMed)
(2) The oxidative stress index increases among patients with hyperemesis gravidarum but not in normal pregnancies by Yilmaz S, Ozgu-Erdinc AS, Demirtas C, Ozturk G, Erkaya S, Uygur D.(PubMed)
(3) Dietary antioxidant levels in hyperemesis gravidarum: a case control study by Celik F1, Guzel AI, Kuyumcuoglu U, Celik Y.(PubMed)
(4) Ginger treatment of hyperemesis gravidarum by Fischer-Rasmussen W1, Kjaer SK, Dahl C, Asping U.(PubMed)
(5) Hyperemesis gravidarum: a review. by Sonkusare S1.(PubMed)
(6) Nausea and vomiting in early pregnancy by Festin M1.(PubMed)
(7) [Treatment of hyperemesis gravidarum with combined inositol and pyridoxine].[Article in Italian] by BALESTRI F.(PubMed)
(8) Ondansetron compared with doxylamine and pyridoxine for treatment of nausea in pregnancy: a randomized controlled trial by Oliveira LG1, Capp SM, You WB, Riffenburgh RH, Carstairs SD.(PubMed)
Posted by at No comments:

Monday, February 1, 2016

The Fabulous Smoothie of Tomato, Grape and Green Tea for Reduced Risk and Treatment of Bowen's disease (BD)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for reduced risk and treatment of Bowen's disease (BD)

Yield: 2 serving (about 8 ounce each)
3/4 cup tomatoes
3/4 cup grape
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Bowen's disease (BD) has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Bowen's disease (BD), an early stage of skin disease with characteristics of red, scaly patch on the skin. There is a suggestion that the diseases in early stage of skin cancer  may be resulted of arsenic exposure  causes of oxidative stress and alternation of DNA(2), in the groundwater of many under developed countries, affecting 200 million people(1).

It is hard to image that a curable smoothie with detoxified property may have a potential in reduced risk of the disease in people who constantly involved to the exposure to arsenic. But due to lack of knowledge of the progression of the diseases in early stage of skin cancer in general population, the finding of these natural ingredients has run into many obstacles.

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc. Its phytochemical curcumin exhibited anti-inflammatory, antiplatelet, antioxidative, hepatoprotective and antitumor activities, particularly against many types of cancers, including skin cancer(4).
 In the phase I clinical trial, researchers suggested that curcumin may be the next potential in the chemoprevention of cancer due to its biologic effect(3).
When used conjunction with LED blue light united red light irradiation, curcumin induced a higher efficiency of regulating proliferation and apoptosis in skin keratinocytes in skin cancer(5).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects.
Its antioxidant (-)-Epigallocatechin-3-gallate (EGCG), has shown effectively in inhibited development of melanoma and nonmelanoma skin cancers(7), through its chemopreventive activity(8).
Dr. Katiyar SK, researcher at the Birmingham Veterans Affairs Medical Center said," The DNA repair by GTPs is mediated through the induction of interleukin (IL)-12(Pro inflammatory cytokine) which has been shown to have DNA repair ability"(6).

Myricetin is a flavonol, belongings to the flavonoid in Flavonoids (polyphenols), found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, used in folk medicine as antioxidant to lower cholesterol, treat certain types of cancer, etc. According to the Kyungpook National University, the phytochemical inhibited the skin cancer formation through its effect on cancer cell cycle division in SKH1-Elite Mice model(9) as well as suppressing UVB-induced cyclooxygenase-2 (COX-2) expression of pain and inflammation of mouse skin epidermal JB6 P+ cells(10) in the early stage of non-melanoma skin cancer(11).

The effectiveness of Tomato, Grape and Green Tea  phytochemicals on Bowen's disease (BD)  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk treatment of stroke with little or no adverse effects.
People who are at high risk of Bowen's disease (BD) due to family history, obesity,..... should drink at least one serving daily and people with Bowen's disease (BD) should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca



References
(1) The mechanistic basis of arsenicosis: pathogenesis of skin cancer by Hunt KM1, Srivastava RK2, Elmets CA2, Athar M3.(PubMed)
(2) Involvement of mtDNA damage elicited by oxidative stress in the arsenical skin cancers by Lee CH1, Wu SB, Hong CH, Chen GS, Wei YH, Yu HS.(PubMed)
(3) Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions by Cheng AL1, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS, Ko JY, Lin JT, Lin BR, Ming-Shiang W, Yu HS, Jee SH, Chen GS, Chen TM, Chen CA, Lai MK, Pu YS,Pan MH, Wang YJ, Tsai CC, Hsieh CY.(PubMed)
(4) Biological and therapeutic activities, and anticancer properties of curcumin by Perrone D1, Ardito F1, Giannatempo G1, Dioguardi M1, Troiano G1, Lo Russo L1, DE Lillo A1, Laino L1, Lo Muzio L1.(PubMed)
(5) Red Light Combined with Blue Light Irradiation Regulates Proliferation and Apoptosis in Skin Keratinocytes in Combination with Low Concentrations of Curcumin by Niu T1, Tian Y2, Cai Q3, Ren Q3, Wei L3.(PubMed)
(6) Green tea prevents non-melanoma skin cancer by enhancing DNA repair by Katiyar SK1.(PubMed)
(7) Green tea and skin cancer: photoimmunology, angiogenesis and DNA repair by Katiyar S1, Elmets CA, Katiyar SK.(PubMed)
(8) (-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity by Barthelman M1, Bair WB 3rd, Stickland KK, Chen W, Timmermann BN, Valcic S, Dong Z, Bowden GT.(PubMed)
(9) Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis by Kang NJ1, Jung SK, Lee KW, Lee HJ.(PubMed)
(10) Myricetin suppresses UVB-induced skin cancer by targeting Fyn by Jung SK1, Lee KW, Byun S, Kang NJ, Lim SH, Heo YS, Bode AM, Bowden GT, Lee HJ, Dong Z.(PubMed)
(11) Myricetin inhibits Akt survival signaling and induces Bad-mediated apoptosis in a low dose ultraviolet (UV)-B-irradiated HaCaT human immortalized keratinocytes by Kim W1, Yang HJ, Youn H, Yun YJ, Seong KM, Youn B.(PubMed)
Posted by at No comments:

Most Common Diseases of elder: Chronic obstructive pulmonary disease (COPD) (Respiratory Disease): The Do and Do not's list

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                         Respiratory Disease 
Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Chronic obstructive pulmonary disease (COPD))is the third leading cause of death in the United State.

  Types of Chronic obstructive pulmonary disease (COPD)


1. Emphysema, a type of Chronic obstructive pulmonary disease (COPD), is defined as a long term and progressive condition cause of shortness of breath but depending to the stage of lung function as a result of damage to tissues of the air sacs (alveoli) in the lungs. In the study of 63 patients with stable COPD (spirometric GOLD stages 2–4) and 17 age- and comorbidity-matched controls, researchers found that in contrast to asthma, COPD is characterised by elevated concentrations of both BDNF and TGF-beta1 in serum. The stage-dependent association with lung function supports the hypothesis that these platelet mediators may play a role in the pathogenesis of COPD(1). In some cases, but rarely, Emphysema is caused by Alpha-1 antitrypsin deficiency emphysema.

2. Chronic bronchitis
Chronic bronchitis is a chronic inflammation of the lung’s bronchi cause of the increased production of mucus in the lung of that leading to difficult breathing.

                     The Prevention

                               The Do and Do not's list

1. Quit smoking, if you don’t, do not try as smoking is the main cause of chronic obstructive pulmonary disease (COPD). People with low levels of the protein alpha-1 antitrypsin are susceptible to develop the disease. Tobacco smoke is a complex chemical aerosol containing at least 8000 chemical constituents, either tobacco derived or added by tobacco product manufacturers(29a)
2. If you working in the occupation in the environment exposure of exposures coal mine dust, silica, welding fume, textile dust, agricultural dust, cadmium fume, etc., please be cautious to avoid the development of the disease(30)
3. Prevent Vitamin D deficiency
In the study of the Effects of vitamin D on immune disorders with special regard to asthma, COPD and autoimmune diseases, researchers at the School of Medicine, Semmelweis University, showed that VD supplementation in most related studies reduced the prevalence of asthma. VD supplementation may be useful in the prevention or adjunct treatment of chronic obstructive pulmonary disease(31).
4. Vitamin C, D, E, A, beta and alpha carotene
In the study of a systematic literature review performed on the association of vitamins and COPD. The role of vitamin supplements in COPD, showed that various vitamins (vitamin C, D, E, A, beta and alpha carotene) are associated with improvement in features of COPD such as symptoms, exacerbations and pulmonary function. High vitamin intake would probably reduce the annual decline of FEV1(32).
5. Antioxidants
Asthma and chronic obstructive pulmonary disease (COPD) are inflammatory lung diseases that are characterized by systemic and chronic localized inflammation and oxidative stress. In the study to elevate amounts of reactive oxygen species (ROS) released from inflammatory cells, increased levels of ROS, either directly or via the formation of lipid peroxidation products, may play a role in enhancing the inflammatory response in both asthma and COPD, researchers at the Novartis Institutes for Biomedical Research, showed that a combination of antioxidants may be effective in the treatment of asthma and COPD(33).
6. Eat your vegetables and fruit
In the study to assess whether the risk of certain chronic diseases can be reduced by increased consumption of vegetables or fruit by the general public, and what strength of evidence has to be allocated to such an association, showed that increasing the consumption of vegetables and fruit lowers the risk of certain eye diseases, dementia and the risk of osteoporosis. Likewise, current data on asthma, COPD, and RA indicate that an increase in vegetable and fruit consumption may contribute to the prevention of these diseases(34). Guidelines from the US National Cancer Institute (103) recommend consumption of five servings of fruit and vegetables daily, corresponding to a vitamin C intake exceeding 200 mg. Dietary surveys carried out in the US population indicate that less than 12 percent of US children and adults meet this recommended level of intake (104). Diet appears to be an important cofactor in the development of obstructive lung disease, although data are still sparse(32a).
7. Etc.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://respiratory-research.com/content/13/1/116/abstract
(29a) http://www.ncbi.nlm.nih.gov/pubmed/23227851
(30) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1513231/
(31) http://www.ncbi.nlm.nih.gov/pubmed/23234453
(32) http://www.ncbi.nlm.nih.gov/pubmed/21134250
(32a) http://www.ncbi.nlm.nih.gov/pubmed/12192737
Posted by at No comments:

The Incredible and Effective smoothie for reduced risk and treatment of Melanoma

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for reduced risk and treatment of melanoma

Yield: 2 servings (about 8 ounces each)
3/4 cup tomatoes
3/4 cup grape
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of melanoma has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Skin cancer is a medical condition of uncontrolled growth of abnormal skin cells and often detected at an early stage. Melanoma is a kind of skin cancer but less common to other skin cancer as a result of malignancy of melanocytes, which are the cell produced dark pigment for the skin.

Recent reports from some well known institutions suggested that certain food sources such as green tea and tomato may be effective for reduced risk and treatment of basal cell cancer, one of most common type of skin cancer.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the joint study lead by the University of Alabama at Birmingham, polyphenols from green tea inhibited the gene expression of protein HDAC in induction of DNA damage, in melanoma cell lines (A375, Hs294t, SK-Mel28 and SK-Mel119) through cell cycle arrest(1).

Another phytochemical, catechins also has the ability to inhibit melanoma cell invasion/migration, an essential step of metastasis, by targeting the endogenous expression of induced cell migration(2).
The joint study lead by the National Taiwan Ocean University also support the notion of green tea intake and reduced risk of melanoma, attached EGCG to nanogold particles (EGCG-pNG) in various ratios showed improved anti-cancer efficacy in B16F10 murine melanoma cells(3).

Tomato is a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. Its phytochemical lycopene, have demonstrated clear anticancer effects toward melanoma(4).
DR. Wu WB and colleagues at the Fu-Jen Catholic University said, " Lycopene, a natural carotenoid that is abundant in tomato,..... compromised melanoma-induced fibroblast migration and attenuated signalling transduction in fibroblasts simulated by melanoma-derived conditioned medium,... by acting as an inhibitor on stromal cells, tumour cells and their interactions, which may contribute to its anti-tumour activity.(5).
Furthermore, according to the National Institutes of Health, Bethesda, Diets consisting of foods rich in vitamin D and carotenoids and low in alcohol may lower the risk of melanoma(6).

Grape is a woody vines of the genus Vitis, belongings to the family Vitaceae, native to southern Turkey. Its phytochemical resveratrol, may consist an antioxidant effect in reduced melanoma risk(7).
According to the Duke University Medical Center, Durham, resveratrol (RESV) showed promise as a novel therapeutic in the management of melanoma through its cytotoxicity effect(8).
The combination of natural compounds ursolic acid (UA) and resveratrol (RES), according to the The University of Texas Health Science Center at San Antonio, also synergistically reduces the viability of B16F10 and A375 melanoma cells, through inhibition of autophagy(9).

The combination of Green tea, Tomato and Grape smoothie may hold a key to reduce risk for people who are at higher risk of  melanoma as well as for treatment of patient who have already developed the disease. People with  melanoma in any stage should drink as much as they can, depending to the digestive toleration..
Life style and diet pattern change are recommended

Made From Fresh Fruits And Vegetable Recipes
Secret To A Vibrant And Healthy Lifestyle
That You Can Find Easily At The Comfort Of Your Kitchen.


All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

References
(1) Polyphenols from green tea inhibit the growth of melanoma cells through inhibition of class I histone deacetylases and induction of DNA damage by Prasad R1, Katiyar SK2.(PubMed)
(2) Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition by Singh T1, Katiyar SK.(PubMed)
(3) Improving anticancer efficacy of (-)-epigallocatechin-3-gallate gold nanoparticles in murine B16F10 melanomacells by Chen CC1, Hsieh DS2, Huang KJ3, Chan YL4, Hong PD5, Yeh MK6, Wu CJ7.(PubMed)
(4) Nutrition: the future of melanoma prevention? by Tong LX1, Young LC2.(PubMed)
(5) Inhibitory effect of lycopene on PDGF-BB-induced signalling and migration in human dermal fibroblasts: a possible target for cancer by Wu WB1, Chiang HS, Fang JY, Hung CF.(PubMed)
(6) Diet and melanoma in a case-control study by Millen AE1, Tucker MA, Hartge P, Halpern A, Elder DE, Guerry D 4th, Holly EA, Sagebiel RW, Potischman N.(PubMed)
(7) Diet in dermatology: Part II. Melanoma, chronic urticaria, and psoriasis by Murzaku EC1, Bronsnick T2, Rao BK1.(PubMed)
(8) Enhancing melanoma treatment with resveratrol by Osmond GW1, Augustine CK, Zipfel PA, Padussis J, Tyler DS.(PubMed)
(9) Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability by Junco JJ1, Mancha-Ramirez A, Malik G, Wei SJ, Kim DJ, Liang H, Slaga TJ.(PubMed)
Posted by at No comments:

Most Common Diseases of elder: Chronic obstructive pulmonary disease (COPD) (Respiratory Disease): The Prevention Diet

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                         Respiratory Disease 
Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.
Chronic obstructive pulmonary disease (COPD))is the third leading cause of death in the United State.

  Types of Chronic obstructive pulmonary disease (COPD)


1. Emphysema, a type of Chronic obstructive pulmonary disease (COPD), is defined as a long term and progressive condition cause of shortness of breath but depending to the stage of lung function as a result of damage to tissues of the air sacs (alveoli) in the lungs. In the study of 63 patients with stable COPD (spirometric GOLD stages 2–4) and 17 age- and comorbidity-matched controls, researchers found that in contrast to asthma, COPD is characterised by elevated concentrations of both BDNF and TGF-beta1 in serum. The stage-dependent association with lung function supports the hypothesis that these platelet mediators may play a role in the pathogenesis of COPD(1). In some cases, but rarely, Emphysema is caused by Alpha-1 antitrypsin deficiency emphysema.

2. Chronic bronchitis
Chronic bronchitis is a chronic inflammation of the lung’s bronchi cause of the increased production of mucus in the lung of that leading to difficult breathing.

                                 The Prevention Diet

1. Neotropical blueberry and barley leaves
In the study of four flavone C-glycosides, isoorientin (1), orientin (2), vitexin (3), and isovitexin (4), isolated from the neotropical blueberry, using antioxidant activity-guided fractionation, found that he four flavone C-glycosides exhibited inhibitory activity against IL-8 production and MMP-1 expression, with compounds 1, 3, and 4 having the most potent inhibitory activities in both assays at 100 μg/ml(1).
2. Turmeric
Cadmium is a toxic metal present in the environment and its inhalation can lead to pulmonary disease such as lung cancer and chronic obstructive pulmonary disease. These lung diseases are characterized by chronic inflammation. In the study of Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium, researchers found that the natural antioxidant curcumin could prevent both cadmium-induced IL-6 and IL-8 secretion by human airway epithelial cells. In conclusion, curcumin could be used to prevent airway inflammation due to cadmium inhalation(2).
3. Oats, sweet corn and rice
Oats, sweet corn and rice contain measurable amounts of melatonin. In recent studies show that, α, β-unsaturated aldehyde acrolein in CS induces the production of interleukin (IL)-8, which is known to be related to bronchitis, rhinitis, pulmonary fibrosis, and asthma. In addition, lung and pulmonary fibroblasts secrete IL-8, which has a chemotactic effect on leukocytes, and which in turn, play a critical role in lung inflammation. Acrolein-induced IL-8 production was accompanied by increased levels of phosphorylation of Akt and extracellular signal-regulated kinases (ERK1/2) in HPFs, and that melatonin suppressed IL-8 production in HPFs. These results suggest that melatonin suppresses acrolein-induced IL-8 production via ERK1/2 and phosphatidylinositol 3-kinase (PI3K)/Akt signal inhibition in HPFs(3).
4. Grape skin
In the study of the effects of grape skin in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD), showed that alteration of the oxidant-antioxidant balance is important in the pathogenesis of CS-induced ALI and suggests lung protective effects of GSE treatment in the mouse(4).
5. Grape skin, seed and red wine
In the study to investigate the effect of dexamethasone versus resveratrol on the release of COPD-related inflammatory mediators (IL-6, IL-8, GM-CSF and MCP-1) and matrix-metalloprotease-9 (MMP-9) from alveolar macrophages exposed to gram-negative bacterial endotoxin (lipopolysaccharide, LPS), found that resveratrol almost completely reduced the release of all cytokines and MMP-9 without significant differences between the cohorts. Our data provide evidence for a corticosteroid resistance of alveolar macrophage-dependent inflammatory responses induced by gram-negative bacteria in COPD and thus question the utility of corticosteroids in COPD therapy. Instead, resveratrol may prove an alternative(5).
6. Etc.
Posted by at 1 comment:
Subscribe to: Posts (Atom)