Medical Advisor Journals

Wednesday, February 24, 2016

The Fabulous Smoothie of Green Tea, Blueberry and Strawberry for reduced Risk and Treatment of Mouth (Oral) cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Oral cancer
Yield: 2 serving (about 8 ounce each)
3/4 cup blueberry
3/4 cup strawberry
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for treatment of Mouth (Oral) cancer is considered as a dream of many scientist to replace the long term usage adverse effect of conventional medicine. Unfortunately, many compounds found effective in initial studying failed to confirm the potential in large sample size and multi center.

Oral cancer is any malignant cell growth in the tissue located in the oral cavity, including the tissue of the lips or the tongue, cheek lining, floor of the mouth, gums (gingiva) and the roof of the mouth (palate).

Recent studies conducted by some renowned institutions, expressed the interest of formula containing green tea, blueberry and strawberry in reduced risk and treatment of oral cancer.

Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Its phytochemicals have been found to process anti cancer effects through different mechanisms. Epigallocatechin-3-gallate, a major bioactive component of green tea, suppressed SSC-4 human oral squamous cell carcinoma (OSCC) cell line proliferation, through activation of apoptosis and autophagy(2) and depending on the differential prooxidant effects in cancer and normal cells(4).

According of he Fujian Medical University,said, "Tea consumption, age of tea drinking initiation, duration of tea consumption, average daily tea consumed, concentration of teaconsumed, types of tea and temperature of tea might have impact on the incidence of oral cancer"(1).

Dr. Zhang W and the colleagues at the Qilu Hospital of Shandong University in the review of literature conducted before January 2014 in MEDLINE and EMBASE databases suggested, tea consumption was associated with decreased risk of oral cancer(3).

Polyphenols found abundantly in blue berry, which is a flower plant, belongings to the family Eriaceae, native to Northern America, is a phytochemical in the class of Stilbenoids also exhibited anti oral cancer effects through suppressed the proliferation and induced G2/M cell cycle arrest and apoptosis of oral cancer KB cells in dose-depend manner(5).

Dr. Iriti M and Dr. Varoni EM. said, " the chemopreventive potential of flavonoids and flavonoid-rich foods, (including blue barry) in human oral carcinogenesis" base on "data from clinical trials and epidemiological studies, in comparison to in vitro/in vivo investigations"(6).

Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits. According to the The Ohio State University, the fruits can inhibit tumor formation in an animal model of oral cancer(7).Dr. Seeram NP and colleagues at the University of California in the study of the effects of berries against cancers found that, berry, including strawberry phenolics anthocyanins, flavonols, flavanols, ellagitannins, gallotannins, proanthocyanidins, and phenolic acids, ameliorated the growth of human oral (KB, CAL-27), with a significant pro-apoptotic effects(8).

The combination of Green Tea, Blueberry and Strawberry smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of Mouth (Oral) cancer without inducing adverse effects.

People who are at higher risk of mouth (oral) cancer due to family history,.......should take at least one serving daily. People with mouth (oral) cancer should drink as much as they can depending to the digestive toleration.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) [Effect of tea on oral cancer in nonsmokers and nondrinkers: a case-control study].[Article in Chinese] by Chen F1, He B2, Huang J, Liu F, Yan L, Hu Z, Lin L, He F.(PubMed)

(2) Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancerSSC-4 cells by Irimie AI1, Braicu C2, Zanoaga O2, Pileczki V3, Gherman C4, Berindan-Neagoe I5, Campian RS6.(PubMed)

(3) Tea intake and risk of oral, pharyngeal, and laryngeal carcinoma: a meta-analysis by Zhang W1, Geng T2, Han W1, Dou H3.(PubMed)

(4) Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling by Tao L1, Park JY, Lambert JD.(PubMed)

(5) Blueberry anthocyanins induce G2/M cell cycle arrest and apoptosis of oral cancer KB cells through down-regulation methylation of p53].[Article in Chinese] by Qi C1, Li S1, Jia Y1, Wang L1.(PubMed)

(6) Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies. by Iriti M1, Varoni EM.(PubMed)

(7) Chemoprevention of oral cancer by lyophilized strawberries by Casto BC1, Knobloch TJ, Galioto RL, Yu Z, Accurso BT, Warner BM.(PubMed)

(8) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro by Seeram NP1, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – Bronchitis – The Causes

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Lower respiratory tract infection

The lower respiratory tract infection are the infection consisting of the trachea (wind pipe), bronchial tubes, the bronchioles, and the lungs, including the bronchitis and pneumonia. According to The World Health Report 2004 – Changing History(1), in 2002 lower respiratory track infection were still the leading cause of deaths among all infectious diseases, and accounted for 3.9 million deaths worldwide and 6.9% of all deaths that year.

Bronchitis

Bronchitis is defined as a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma(7). Most cases of Bronchitis are as a result of recurrent injure to the airways caused by inhaled irritants and cigarette smoking(6). There are 2 types of bronchitis
The Causes
A.1.1. Acute bronchitis
The most common causes of acute brochitis are as result of the infection due to the invasion of Virus, (influenza and cold). Prolonged activity of the presence of the virus can have many deteriorative effects.Young adults with underlying medical conditions who are infected with the H1N1 virus are at risk of quickly progressing from mild upper airways infection to severe ARDS within 4 to 5 days after the onset of the illness. According to the study by Dr. Homsi S and the research team, there is a report of a case a 46-year-old morbidly obese and diabetic woman infected with the H1N1 virus who developed acute bronchitis that lasted for 4 weeks and then progressed to ARDS. The month-long persistence of the H1N1 viral bronchitis and its late progression to ARDS which may reflect prolonged viral activity. Such a prolonged, rather than quick, course of deterioration can cause clinicians to misdiagnose the etiology of the ARDS and may cause the patient to receive a prolonged treatment with steroids to treat bronchitis symptoms(8).
Other in the reviewed study of reported eight cases of influenza A (H1N1) 2009 admitted to themedical intensive care with severe respiratory failure between November and December 2009 and in January 2011. All patients were older than 30 but younger than 50 years, had clinical and radiological evidence of an Acute Respiratory Distress Syndrome (ARDS) and needed invasive ventilatory support. The clinical course of severe cases of influenza A (H1N1) 2009-infection is markedly different from the disease pattern seen during epidemics of seasonal influenza. Most of the patients admitted to our intensive care unit due to influenza A (H1N1) 2009 associated ARDS were previously healthy young people, according to the University Hospital of Muenster(9).
A.1.2. Chronic bronchitis
Most common causes of chronic bronchitis are as result of chronically smoking cigarettes, air pollution, dust. toxic gases, etc.
1. Smoking
In the case-control study in Beirut in 2009/2010 to evaluate the relationship: 274 cases of chronic bronchitis and 559 controls without the condition aged > or = 40 years, conducted by Lebanese University Beirut, found that current waterpipe dependence was significantly associated with chronic bronchitis (OR = 3.74, P < 0.001). After adjustment for covariates/confounders, ever waterpipe smoking > 20 WP-years (P < 0.001) was significantly associated with chronic bronchitis(10).
Other study indicated that in a retrospective clinical and morphological study on a group of 17 smoker patients with symptoms of chronic bronchitis, eight non-smokers diagnosed with chronic bronchitis and five non-smokers and asymptomatic subjects. CB developed especially in men of 65-year-old or older, especially in smokers with a median FEV1% at around 71. Histopathologically, patients with symptoms of CB, regardless of smoking status, presented on bronchial biopsies with focal squamous metaplastic change, goblet cell hyperplasia and enlargement of the bronchial gland mass because of the inflammatory process, consisting predominantly of mononuclear cells in the bronchial wall. The statistical testing proved a significant correlation between the densities of different inflammatory cell classes (with the exception of mast cells in the bronchial epithelium) and FEV1% values on epithelium and submucosa regions in all investigated groups(11).
2. Air pollution, dust. toxic gases and other occupational chemical exposures
In the study to ascertain chronic obstructive pulmonary disease (COPD) prevalence among industrial workers in the Russian Federation and determine relative contribution of smoking and occupational factors to COPD of 1,375 workers aged 30 or over, found that those with airfl ow limitation of FEV1/FVC<0.70 were considered having COPD and those with presence of cough and sputum production for at least three months in each of two consecutive years were considered having chronic bronchitis (CB), with no overlapping between these 2 groups. Data on occupational history and VGDF levels in the working area were collected from all participants. In total, 105 cases of COPD and 170 cases of CB were diagnosed in the cohort of examined workers. Occupational exposure to VGDF was twice as often present among COPD patients than among both patients with CB and the control group of healthy workers (p<0.05). More than 40 % of COPD patients were occupationally exposed to VGDF above the value of 3.0 of the occupational exposure limit (OEL) and more than 20 % to 6.0 OEL and higher. Overall odds ratio for COPD development due to occupational VGDF exposure was 5.9 (95 % CI=3.6 to 9.8, p=0.0001). Both smoking and VGDF seem to be important for the development of COPD. Analysis of the combined effect of tobacco smoking and occupational noxious particles and gases on COPD development has shown the following order of risk factors based on the strength of their influence: VGDF levels, smoking index, age, and heating microclimate(12).

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.who.int/whr/2004/en/
(8) http://www.ncbi.nlm.nih.gov/pubmed/22977983
(9) http://www.ncbi.nlm.nih.gov/pubmed/22075296
(10) http://www.ncbi.nlm.nih.gov/pubmed/23301353
(11) http://www.ncbi.nlm.nih.gov/pubmed/22990540
(12) http://www.ncbi.nlm.nih.gov/pubmed/23152384

Tuesday, February 23, 2016

The Smoothie Green Tea, Grape and Curcumin for Reduced Risk and Treatment of Hidradenitis Suppurativa (HS)

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Hidradenitis suppurativa (HS)

Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of Hidradenitis suppurativa (HS) without adverse effects in replacement of conventional medicine has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Hidradenitis suppurativa (HS) is a condition of skin disease with the development of pimple-like bumps mostly on areas of armpits, groin, inducing long-term skin inflammation and pain.

Recent studies reported by numerous well known institution, green tea, grape and may process anti skin inflammatory diseases properties(1) in reduced risk and treatment of chronic hidradenitis suppurativa (HS) without persuaded adverse effects.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.According to the Institute of Information Technology, green tea exerted its therapeutic properties of anti skin infectious effects through inhibition of adhesion at its minimal inhibitory concentration (MIC) value(2).

Dr. Lee JH and colleagues at the Korea University, said, "Green tea extract-4 (CSI-4) exert a selective anti-adhesive effect against certain pathogenic bacteria with no adverse effects against beneficial or commensal bacteria."(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape also displays antioxidant, anti-inflammatory, antimicrobial activities in reduced risk and treatment of skin diseases(4).

In skin inflammatory in mice, resveratrol exerted strongly anti-inflammatory effects in various cells, tissues, animals and human settings of low-grade inflammation, through anti proinflammatory patways, su as IL-17A and IL-19(5).

With its anti-inflammation associated with immune responses, resveratrol also attenuated atopic dermatitis (AD) mouse model by modulating the HMGB1 protein expression, in targeting skin inflammation(6).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

Its major phytochemical constituent curcumin used conjunction with resveratrol were excellent candidates for skin treatment, according to joint study lead by the Saarland University(4).

Dr. Sun J and colleagues at the General Hospital of Jinan Military Command, said, " Curcumin has been confirmed to have anti-inflammatory properties in addition to the ability to decrease the expression of pro-inflammatory cytokines in keratinocytes"(7).

Furthermore, according to the, topical administration of curcumin may effectively use for treatment of skin-related disorders. due to its property of directly deliver to the affected tissue(8).

The discovery of combined ingredients of green tea, grape, and turmeric may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of Hidradenitis suppurativa (HS).

People who are at increased risk of Hidradenitis suppurativa (HS) due to family history, aging,... may drink one or 2 servings a day, people with Hidradenitis suppurativa (HS) should drink as much as they can depending to the digestive alternation.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) A new function of green tea: prevention of lifestyle-related diseases by Sueoka N1, Suganuma M, Sueoka E, Okabe S, Matsuyama S, Imai K, Nakachi K, Fujiki H.(PubMed)

(2) Green tea extract: possible mechanism and antibacterial activity on skin pathogens By Sharma A1, Gupta S, Sarethy IP, Dang S, Gabrani R.(PubMed)

(3) In vitro anti-adhesive activity of green tea extract against pathogen adhesion by Lee JH1, Shim JS, Chung MS, Lim ST, Kim KH.(PubMed

(4) Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratroland curcumin. by Friedrich RB1, Kann B2, Coradini K1, Offerhaus HL3, Beck RC4, Windbergs M5.(PubMed)

(5) Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. by Kjær TN1, Thorsen K2, Jessen N2, Stenderup K3, Pedersen SB1.(PubMed)

(6) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice. by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)

(7) Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice. by Sun J1, Zhao Y2, Jin H3, Hu J4.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – The Classification

The Classification

Two most common types of lower respiratory track infection, include
B.1. Bronchitis
Bronchitis is defined as a condition of an inflammation of the mucous membranes of the bronchi, the larger and medium-sized airways that carry airflow from the trachea into the lung parenchyma(7). Most cases ofBronchitis are as a result of recurrent injure to the airways caused by inhaled irritants and cigarette smoking(6). There are 2 types of bronchitis
1. Acute Bronchitis
Short term infection with symptoms of green sputum, chest discomfort or soreness, fever as a result of cold or flu of which only last for a few days.

2. Chronic Bronchitis
Chronic bronchitis is defined as phlegm on most days, at least 3 months per year for ≥ 2 yrs or cough and phlegm on most days, at least 3 months per year for ≥ 2 yrs(7).
B.2. Pneumonia
Pneumonia is defined as a condition of the inflammation of the lung as a result of infection, caused by bacteria, such as bacteria Streptococcus pneumoniae or influenza viruses in most cases. Fungi, such as Pneumocystis jiroveci, certain medication such as PPI Stomach Acid Drugs and other conditions such as impaired immune systems can also induced the disease.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to General health http://kylejnorton.blogspot.ca/p/general-health.html

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) http://www.who.int/whr/2004/en/
(6) http://www.ncbi.nlm.nih.gov/pubmed/23209933
(7) http://www.ncbi.nlm.nih.gov/pubmed/21687549

Monday, February 22, 2016

The Delicious Smoothie of Green Tea, grape and Tomato for Reduced Risk and Treatment of Larynx (Voice Box) Cancer/Laryngeal Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Larynx (Voice Box) Cancer/Laryngeal Cancer
Yield: 2 serving (about 8 ounce each)
3/4 cup grape
3/4 cup tomato
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

Back by well known institution, according to the recent studies, green tea(1), may be next potential therapeutic target for producing a curable medication for reduced risk and treatment of larynx (voice box) cancer/laryngeal cancer

Larynx cancer is also known as cancer of the larynx or laryngeal carcinoma, developed in any part of the larynx. Most larynx cancers are squamous cell carcinomas as a result of uncontrolled multiplication of transformed malignant cells in the laryngeal epithelium originated in the glottis.

According to The Food Technology and Biotechnology, flavonoid constituents of gree tea epigallocatechin gallate (EGCG) and epicatechin gallate (ECG) on human laryngeal carcinoma cell line (HEp2) through exhibition of scavenge free radicals, and induce pro-oxidative reactions in the cell(1).

The portion of phytochemical Epigallocatechin-3-gallate (EGCG), inhibited the progression of aryngealsquamous cell carcinoma (LSCC) through induced apoptosis via inhibiting the telomerase activity in stopping the divide indefinitely of cells incancer forming(2) as well as induced apoptosis through cell cycle arrest(3).
Flavonoids found abundantly in grape may also exert the potential effect in preventing and treating Laryngeal Cancer. Dr. Garavello W and the research team at the Istituto di Ricerche Farmacologiche Mario Negri suggested(4).

Resveratrol, another phytochemical found in grape also strongly depress cell growth and inhibit cell proliferation in human Hep-2 cell in a time- and dose-dependent manner(5).

Dr. Li T and colleagues at the Medical School of Xi'an Jiaotong University said, "resveratrol could strengthen anti-tumor immunoresponse, accommodating lymphocyte to secrete cytokine, through which it exerted the efficiency of anti-laryngocarcinoma"(6) and "improved function of T, B lymphocytes, killing activity of NK cells, release of antibodies, and the total complement activity in serum"(7).

Tomato is a red, edible fruit, genus Solanum, belongings to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house. As a diet rich in carotenoids has shown to protect against head and neck cancer(10).

Tomato major chemical constituents, retinol, alpha-tocopherol, and carotenoids

offer protection from oxidative damage and potentiate the immune system against the forming of
cancer of the larynx(8).

According to the Yale University School of Medicine, plasma lycopene was significantly associated (inversely) with total mortality in the full study population with oral, pharynx or larynx cancers(9).

The identification of combined ingredients of green tea(1), grape(4) and tomato(7) may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of laryngeal Cancer

People who are at increased risk of laryngeal Cancer due to family history, gene mutation, obesity.....should drink at least one serving daily and people with laryngeal Cancer should drink no more than 4 serving a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References

(1) Genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro by Durgo K1, Kostić S, Gradiški K, Komes D, Osmak M, Franekić J.(PubMed)

(2) Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression by Wang X1, Hao MW, Dong K, Lin F, Ren JH, Zhang HZ.(PubMed)

(3) EGCG induces apoptosis in human laryngeal epidermoid carcinoma Hep2 cells via mitochondria with the release of apoptosis-inducing factor and endonuclease G. by Lee JH1, Jeong YJ, Lee SW, Kim D, Oh SJ, Lim HS, Oh HK, Kim SH, Kim WJ, Jung JY.(PubMed)
(4) Flavonoids and laryngeal cancer risk in Italy by Garavello W1, Rossi M, McLaughlin JK, Bosetti C, Negri E, Lagiou P, Talamini R, Franceschi S, Parpinel M, Dal Maso L, La Vecchia C.(PubMed)
(5) [Inhibit affection of resveratrol on the growth of Hep-2 cell line].[Article in Chinese] by Li Y1, Xu Y, Huang D, Jiang L, Li K.(PubMed)
(6) [Research of a new kind of biological response modifier to anti-laryngocarcinoma].[Article in Chinese] by Li T1, Fan G, Li T, Yuan Y, Shi L.(PubMed)
(7) [Preliminary study on anti-tumor function of resveratrol and its immunological mechanism].[Article in Chinese] by Li T1, Sheng L, Fan GX, Yuan YK, Li T.(PubMed)
(8) Evaluation of retinol, alpha-tocopherol, and carotenoids in serum of men with cancer of the larynx before and after commercial enteral formula feeding by Olmedilla B1, Granado F, Blanco I, Rojas-Hidalgo E.(PubMed)
(9) Low plasma lycopene concentration is associated with increased mortality in a cohort of patients with prior oral, pharynx or larynx cancers by Mayne ST1, Cartmel B, Lin H, Zheng T, Goodwin WJ Jr.(PubMed)
(10) Carotenoid intake and head and neck cancer: a pooled analysis in the International Head and Neck CancerEpidemiology Consortium by Leoncini E1, Edefonti V, Hashibe M, Parpinel M, Cadoni G, Ferraroni M, Serraino D, Matsuo K, Olshan AF, Zevallos JP, Winn DM, Moysich K, Zhang ZF,Morgenstern H, Levi F, Kelsey K, McClean M, Bosetti C, Schantz S, Yu GP, Boffetta P, Lee YC, Chuang SC, Decarli A, La Vecchia C, Boccia S.(PubMed)

Most Common Diseases of elder: Lower respiratory tract infection (Respiratory Disease) – The Symptoms

The Symptoms

According to the study by Independent Travel Health and Immunization Specialist Nurse, Streptococcus pneumoniae is a cause of significant morbidity and mortality worldwide. There are many different serotypes of the organism which may be carried by up to 50% of children under the age of 6 years, as well as many adults. The organism is associated with bothpneumonia and invasive pneumococcal disease, which may result in septicemia or meningitis. It is also a principal cause of otits media and sinusitis, which are not life-threatening, but generate a lot of discomfort, loss of schooling or working days, and around 60 000 GP consultations per year in the UK(2).
1. Shortness of breath, chest pain, abnormal breath sounds and high fever
There is a report of a 65-year-old man with shortness of breath, pleuritic chest pain, and recurrent pneumonia, according to Department of Medical Education.(3). In other study to understand which clinical criteria physicians use to diagnose pneumonia compared to bronchitis and upper respiratory tract infection (URTI), showed that logistic regression analysis identified rales, a temperature > 100 degrees F (37.8 degrees C), chest pain, dyspnoea, rhonchi, heart rate, respiratory rate, and rhinorrhoea. The presence of abnormal breath sounds and a temperature > 100 degrees F were the best predictors of a diagnosis of pneumonia(4).

2. Other symptoms include
According to the study conducted by Nanxiang Hospital of Jiading District of Shangha, the common symptoms of (human bocavirus infection) HBoV-infected patients included frequent coughing, wheezing and fever(5).Others suggested that CAP is usually characterized by fever, chills, dyspnea, cough, and pleuritic chest pain in association with physical findings suggestive of consolidation in persons who become ill outside of a hospital or chronic-care facility(5).
a. Cough, which may be dry at first, but eventually produces phlegm (sputum)as a result of heat accumulation, according to traditional Chinese medicine.
b. Nausea and vomiting
c. muscle aches
d. weakness
e. fatigue
f. etc.

(1) http://www.who.int/whr/2004/en/
(2) http://www.ncbi.nlm.nih.gov/pubmed/22398939
(3) http://www.ncbi.nlm.nih.gov/pubmed/21178155
(4) http://www.ncbi.nlm.nih.gov/pubmed/20490437
(5)http://www.ncbi.nlm.nih.gov/pubmed/21507299

The Smoothie of Alfalfa Sprouts, Panax Ginseng for Prevention and Treatment of Amenorrhea

1 cup Panax ginseng drink (Make from 2 grams of Panax ginseng powder and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Amenorrhea to replace the conventional medicne has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Amenorrhea is a women reproductive health condition of absence of period for at least three cycles (six months), excluding before puberty, during pregnancy, and after menopause.

Estrogen therapy significant increase of serum luteinizing hormone (LH) and LH response to GnRH were noted after recovery in patient with functional hypothalamic amenorrhea (FHA)(1).
According to the Keiju Medical Center, phytoestrogen found in black soy bean resumed the anovular menstrual cycle, suffering from secondary amenorrhea(2).

Injection of phytoestrogen orally may be benefits for women with Amenorrhea as it has shown to consist anti estrogenic and estrogenic(4) effect depending to the levels of estrogen of the patients.

According to University La Sapienza, in the study of a total of 134 women aged 25-35 years, who were infertile for at least 2 years and who had oligomenorrhea or amenorrhea associated with a positive menstrual response to the intramuscular progesterone-challenge test, showed that high dose of phytoestrogens increased follicle-stimulating hormone, luteinizing hormone, and 17beta-estradiol plasma concentrations and can reverse the deleterious effects of clomiphene citrate on endometrial thickness and could contribute to higher pregnancy rates.(3).

Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belongings to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root). The herb(Panax ginseng) may be used for treatment of reduced estrogen levels due to aging in women becaused of its ginsenoside Rb in exhibited phytoestrogen like effects(5).

According to the China Pharmaceutical University in ovariectomized mice study suggested that ginsenoside Rb1 (Rb1) isolated from Panax ginseng, increased 5-hydroxytryptamine (5-HT) concentration via its estrogen-like effect(6).

The effectiveness of Alfalfa Sprouts, Panax Ginseng Powder may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of Amenorrhea with little or no adverse effects.

Women who are pregnancy may want to stop drinking excessively. Otherwise, intake of
Smoothie of Alfalfa Sprouts, Panax Ginseng Powder may Reduced Risk and treatment of Amenorrhea
Life style and dietary patter change are recommended.

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References
(1) Resumption of menstruation and pituitary response to gonadotropin-releasing hormone in functional hypothalamic amenorrhea subjects undertaking estrogen replacement therapy by Shen ZQ1, Xu JJ, Lin JF.(PubMed)
(2) The effect of soybeans on the anovulatory cycle by Kohama T1, Kobayashi H, Inoue M.(PubMed)
(3) High dose of phytoestrogens can reverse the antiestrogenic effects of clomiphene citrate on the endometrium in patients undergoing intrauterine insemination: a randomized trial by bUnfer V1, Casini ML, Costabile L, Mignosa M, Gerli S, Di Renzo GC.(PubMed)
(4) Phytoestrogen content and estrogenic effect of legume fodder by Saloniemi H1, Wähälä K, Nykänen-Kurki P, Kallela K, Saastamoinen I.(PubMed)
(5) Beneficial estrogen-like effects of ginsenoside Rb1, an active component of Panax ginseng, on neural 5-HT disposition and behavioral tasks in ovariectomized mice by Hao K1, Gong P1, Sun SQ1, Hao HP1, Wang GJ1, Dai Y2, Liang Y1, Xie L1, Li FY1.(PubMed)
(6) Mechanism-based pharmacokinetic-pharmacodynamic modeling of the estrogen-like effect of ginsenoside Rb1 on neural 5-HT in ovariectomized mice by Hao K1, Gong P, Sun SQ, Hao HP, Wang GJ, Dai Y, Chen YC, Liang Y, Xie L, Li FY, Li HY.(PubMed)