Tuesday, February 23, 2016

The Smoothie Green Tea, Grape and Curcumin for Reduced Risk and Treatment of Hidradenitis Suppurativa (HS)

Kyle J. Norton (Scholar, and Master of nutrients) All right reserved
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Hidradenitis suppurativa (HS)

Yield: 2 servings (about 8 ounces each)
1 1/2  cups grape
1 tsp curcumin
1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural ingredient for prevention and treatment of Hidradenitis suppurativa (HS) without adverse effects in replacement of conventional medicine has not been abated. Some ingredients have to discard because of not achieving the same potent results in human trials.

Hidradenitis suppurativa (HS) is a condition of skin disease with the development of pimple-like bumps mostly on areas of armpits, groin, inducing long-term skin inflammation and pain.

Recent studies reported by numerous well known institution, green tea, grape and  may process anti skin inflammatory diseases properties(1) in reduced risk and treatment of chronic hidradenitis suppurativa (HS) without persuaded adverse effects.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.According to the Institute of Information Technology, green tea exerted its therapeutic properties of anti skin infectious effects through inhibition of adhesion at its minimal inhibitory concentration (MIC) value(2).
Dr. Lee JH and colleagues at the Korea University, said, "Green tea extract-4 (CSI-4) exert a selective anti-adhesive effect against certain pathogenic bacteria with no adverse effects against beneficial or commensal bacteria."(3).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape also displays antioxidant, anti-inflammatory, antimicrobial activities in reduced risk and treatment of skin diseases(4).
In skin inflammatory in mice, resveratrol exerted strongly anti-inflammatory effects in various cells, tissues, animals and human settings of low-grade inflammation, through anti proinflammatory patways, su as IL-17A and IL-19(5).
With its anti-inflammation associated with immune responses, resveratrol also attenuated atopic dermatitis (AD) mouse model by modulating the HMGB1 protein expression, in targeting skin inflammation(6).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.
Its major phytochemical constituent curcumin used conjunction with resveratrol were excellent candidates for skin treatment, according to joint study lead by the Saarland University(4).
Dr. Sun J and colleagues at the General Hospital of Jinan Military Command, said, " Curcumin has been confirmed to have anti-inflammatory properties in addition to the ability to decrease the expression of pro-inflammatory cytokines in keratinocytes"(7).
Furthermore, according to the, topical administration of curcumin may effectively use for treatment of skin-related disorders. due to its property of directly deliver to the affected tissue(8).

The discovery of combined ingredients of green tea, grape, and turmeric may act as a cornerstone for induction of further investigation of the effectiveness of natural smoothie in reduced risk and treatment of Hidradenitis suppurativa (HS).

People who are at increased risk of Hidradenitis suppurativa (HS) due to family history, aging,... may drink one or 2 servings a day, people with Hidradenitis suppurativa (HS) should drink as much as they can depending to the digestive alternation.

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(1) A new function of green tea: prevention of lifestyle-related diseases by Sueoka N1, Suganuma M, Sueoka E, Okabe S, Matsuyama S, Imai K, Nakachi K, Fujiki H.(PubMed)
(2) Green tea extract: possible mechanism and antibacterial activity on skin pathogens By Sharma A1, Gupta S, Sarethy IP, Dang S, Gabrani R.(PubMed)
(3) In vitro anti-adhesive activity of green tea extract against pathogen adhesion by Lee JH1, Shim JS, Chung MS, Lim ST, Kim KH.(PubMed
(4) Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratroland curcumin. by Friedrich RB1, Kann B2, Coradini K1, Offerhaus HL3, Beck RC4, Windbergs M5.(PubMed)
(5) Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. by Kjær TN1, Thorsen K2, Jessen N2, Stenderup K3, Pedersen SB1.(PubMed)
(6) Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice. by Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Nomoto M, Miyashita S,Suzuki K, Watanabe K.(PubMed)
(7) Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice. by Sun J1, Zhao Y2, Jin H3, Hu J4.(PubMed)

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