Medical Advisor Journals

Saturday, March 19, 2016

The Best Smoothie of Green tea, Grape and Sweet Potato for Prevention and Treatment of Kidney Stones caused by Medullary sponge kidney

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Medullary sponge kidney is a contingent disorder of kidney disease resulted of cystic dilatation of the collecting tubules in one or both kidneys, leading to increased risk of forming of kidney stone and urinary track infection. Most Medullary sponge kidney can be treated by minimally invasive percutaneous nephrolithotomy in the treatment of medullary sponge kidney patients with complex renal calculi(*).

The smoothie for reduced risk and treatment of Kidney stone caused by Medullary sponge kidney
Yield: 2 servings (about 8 ounces each)
1 gram of formula RRF(you cam buy them in any Chinese herbal store)
1 cup grape
1/2 cup sweet potato
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced symptoms and treatment of Kidney stone is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potentials in large sample size and multi center.
Hydronephrosis is a health condition of kidney swelling caused by urine retention. According to the China Medical University, in patients with ureteral stones and colic, a majority (nearly 71 %) will demonstrate only mild hydronephrosis(1).
Kidney stone is a tiny mineral and acid salts form inside your kidneys. recent study back by some renowned institution suggested that green tea(2) may have a potential in reduced risk and treatment of forming of kidney stone.

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the Seoul National University Hospital, epigallocatechin gallate (EGCG), a main constituent of green tea polyphenols processed an inhibitory effect on urinary stone formation, through its anti-oxalate effect(2).

Treatment of Green tea in a total of 120 Wistar rats study also exhibited decreased urinary oxalate excretion and calcium oxalate deposit formation due to antioxidative effects(3).

Dr. Kanlaya R and colleagues in the study led by the Mahidol University said, " EGCG in reducing COM crystal deposition in previous animal models of kidney stone disease. Thus, EGCG may be useful for the prevention of new or recurrent stone formation"(4).

Gallotannin, class of molecules belongings to the hydrolysable tannins found abundantly in grape and blueberry may also exert protective effect against forming of kidney stone(5). According to the Kyung Hee University, gallotannin suppressed calcium oxalate crystal binding and oxalate-induced oxidative stress in renal epithelial cells by upregulating antioxidant expression(5).

Furthermore, the 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose derivative of gallotannin, attenuated renal crystallization and oxidative renal cell injury for treatment of nephrolithiasis(6).

Vitamin E, a fat soluble vitamin found abundantly in sweet potato may also induced protective effect against kidney stone forming through it antioxidant in involvement of free radical-mediated lipid peroxidation-induced membrane damage in the pathogenesis of calcium oxalate crystal deposition and retention(7).

Dr. Thamilselvan S and Dr. Menon M. said, " excess vitamin E completely prevented calcium oxalate deposition, by preventing peroxidative injury and restoring renal tissue antioxidants and glutathione redox balance"(8).

According to the National Taiwan University Hospital, Vitamin E attenuates crystal formation in rat kidneys through educing calcium oxalate accumulation via attenuation of tubular cell death and enhancement of the defensive roles of osteopontinin (OPN), and Tamm-Horsfall protein as crystallization inhibitors(9).

The combination of Green tea, Grape and Sweet Potato smoothie may hold a key in further studies in production of an effective natural ingredients for prevention and treatment of hydronephrosis caused by Kidney Stones without inducing adverse effects.

People who are at increased risk of hydronephrosis caused by Kidney Stones due to drinking habit, family history .....should drink at least one cup daily and people with hydronephrosis caused by Kidney Stones should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern are also recommended.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

References
(*) Safety and efficacy of minimally invasive percutaneous nephrolithotomy in the treatment of patients with medullary sponge kidney by Sun H1, Zhang Z2, Yuan J1, Liu Y1, Lei M1, Luo J1, Wan SP1, Zeng G1.(PubMed)
(1) Can ureteral stones cause pain without causing hydronephrosis? bySong Y1, Hernandez N2, Gee MS3, Noble VE4, Eisner BH5.(PubMed)
(2) Effects of green tea on urinary stone formation: an in vivo and in vitro study by Jeong BC1, Kim BS, Kim JI, Kim HH.(PubMed)
(3) Preventive effects of green tea on renal stone formation and the role of oxidative stress in nephrolithiasis by Itoh Y1, Yasui T, Okada A, Tozawa K, Hayashi Y, Kohri K.(PubMed)
(4) EGCG decreases binding of calcium oxalate monohydrate crystals onto renal tubular cells via decreased surface expression of alpha-enolase by Kanlaya R1,2, Singhto N1,2, Thongboonkerd V3,4.(PubMed)
(5) Gallotannin suppresses calcium oxalate crystal binding and oxalate-induced oxidative stress in renal epithelial cells by Lee HJ1, Jeong SJ, Park MN, Linnes M, Han HJ, Kim JH, Lieske JC, Kim SH.(PubMed)
(6) 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model by Lee HJ1, Jeong SJ, Lee HJ, Lee EO, Bae H, Lieske JC, Kim SH.(PubMed)
(7) Calcium oxalate stone disease: role of lipid peroxidation and antioxidants by Selvam R1.(PubMed)
(8) Vitamin E therapy prevents hyperoxaluria-induced calcium oxalate crystal deposition in the kidney by improving renal tissue antioxidant status by Thamilselvan S1, Menon M.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion- The Risk Factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

The Risk factors

1. Certain Medications
Certain medication such as Nitrofurantoin (Macrodantin, Furadantin, Macrobid), Dantrolene (Dantrium), Methysergide (Sansert), etc. are associsted to increased riak of pleural effusions.
2. Radiation therapy
There is a report of Therapy of pronounced pleural and pericardial effusion in metastatic breast cancer with local mitoxantrone and radiation therapy(28).
3. Acute Lung Injury
Pleural effusion is a frequent finding in patients with acute respiratory distress syndrome. Pleural effusion in acute lung injury or acute respiratory distress syndrome patients is of modest entity and leads to a greater chest wall expansion than lung reduction, without affecting gas exchange or respiratory mechanics, according to the study(29).
4. Nonaccidental trauma (NAT)
Nonaccidental trauma (NAT) is common and presents with varied symptoms..There is a reprot of a case of a of a 10-week-old infant who presented with multiple nonspecific complaints that included respiratory distress, refusal to feed, constipation, and lethargy. Sepsis was the working diagnosis on admission, but a massive pleural effusion and rib fractures seen on chest imaging ultimately led to the diagnosis of nonaccidental trauma(30).
5. Critically ill patients
Pleural effusions (PEs) are common in critically ill patients mainly as a consequence of severe cardiopulmonary disorders frequently encountered in these patients, according to the Medical School, Democritus University of Thrace(31)
6. Blunt thoracoabdominal trauma
Patients wirh blunt thoracoabdominal trauma are associated to higher risk to develop pleural effusions. There is a report of a successful treatment result in a rare case of hepatitis C virus-related cirrhosis, who had sustained hydrothorax after blunt thoracoabdominal trauma. She sustained blunt thoracoabdominal trauma with a left clavicle fracture dislocation and right rib fractures. There was no hemopneumothorax at initial presentation. However, dyspnea and right pleural effusion developed gradually, according to the study by the Taipei-Veterans General Hospital(32).
7. Pregnancy
There is a report of a 40 year old woman at 30 weeks of her eighth pregnancy presented with acute onset of dyspnoea and a large left pleural effusion after the onset of premature labour. A barium enema showed diaphragmatic rupture with intestinal contents in the thorax(33)
7. Other risk factors
According to the study by the, most patients with pleural empyema and complicated parapneumonic pleural effusion were middle aged (53+/-17 years); men were twice as likely as women to have these conditions. Less than half (46%) of patients had at least one risk factor such as neoplasia (37%), treatment with immunosuppressive medicine (15%), alcohol abuse (15%)(34).

Sources
(28) http://www.ncbi.nlm.nih.gov/pubmed/8383901
(29) http://www.ncbi.nlm.nih.gov/pubmed/23385101
(30) http://www.ncbi.nlm.nih.gov/pubmed/22217891
(31) http://www.ncbi.nlm.nih.gov/pubmed/18824883
(32) http://www.ncbi.nlm.nih.gov/pubmed/22901727
(33) http://www.ncbi.nlm.nih.gov/pubmed/3420561
(34) http://www.ncbi.nlm.nih.gov/pubmed/20440084

Friday, March 18, 2016

The Smoothie of Reishi mushroom and Cooked Artichokes for Prevention and Treatment of Primary Biliary Cirrhosis

The finding of a natural source for treatment of Primary Biliary Cirrhosiss has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Primary Biliary Cirrhosis is a condition of slowly destroyed of bile dusts, causing damage to liver as a result of bile building up. Antioxidant therapy is found effectively in improvement of the pruritus and fatigue of PBC(1).

Recent studies back by well known institutions proposed, Reishi mushroom and Cooked Artichokes may be the next generation of natural ingredients for prevention and treatment of Primary Biliary Cirrhosis.
According to the China Medical University, glycyrrhizin, silymarin, and ursodeoxycholic acid may have potential for prevention and treatment of primary biliary cirrhosis due to antioxidants effect in regulated the expression of genes relevant to apoptosis and oxidative stress in HepG2 cells(2).

Glycyrrhizin, found abundantly in Reishi mushroom or Lingzhi is a fungal species in the genus Ganoderma, belongings to the family Ganodermataceae, native to Asia. According to the Wonkwang University, has an antifibrotic effect on fibrotic rats induced by a bile duct ligation and scission (BDL/S)(3).

Silymarin, an antioxidant found in milk thistle and cooked artichokes may also be important ingredient for prevention and treatment of Primary Biliary Cirrhosis(2). According to the joint study led by the University of Foggia, silybin exerted antioxidant effects against accumulation of toxic hydrophobic bile acids in hepatocytes,caused by chronic cholestasis, through inhibition of mitochondrial failure in rat with secondary biliarycirrhosis(4).
Dr. Matveev AV and colleagues in the study of liver protective effects of silymarin ssaid," clinical trials and systematic reviews of silymarin use show high efficacy of the drug in patients with amanitine, drugs, and other toxic injuries of liver, viral hepatitis, NASH. In patients with carcinoma and primarily biliary cirrhosis efficacy of silymarin is ambiguous"(5).

The effectiveness of Reishi mushroom and Cooked Artichokes may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Primary Biliary Cirrhosis with little or no adverse effects.

People who are at high risk of Primary Biliary Cirrhosis due to family history, environment factors, .... should drink at least one serving daily and women with Primary Biliary Cirrhosis should drink the smoothie as much as they can, depending to digestive toleration.

Life style and dietary pattern(reduced intake of bad cholesterol)change are recommended.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Case report: oral antioxidant therapy for the treatment of primary biliary cirrhosis: a pilot study by Watson JP1, Jones DE, James OF, Cann PA, Bramble MG.(PubMed)
(2) Glycyrrhizin, silymarin, and ursodeoxycholic acid regulate a common hepatoprotective pathway in HepG2 cells by Hsiang CY1, Lin LJ2, Kao ST2, Lo HY3, Chou ST3, Ho TY4.(PubMed)
(3) Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction by Park EJ1, Ko G, Kim J, Sohn DH.(PubMed)
(4) Silybin exerts antioxidant effects and induces mitochondrial biogenesis in liver of rat with secondary biliarycirrhosis by Serviddio G1, Bellanti F1, Stanca E2, Lunetti P2, Blonda M1, Tamborra R1, Siculella L2, Vendemiale G1, Capobianco L3, Giudetti AM4.(PubMed)
(5) [Hepatoprotective properties of silymarin].[Article in Russian] by Matveev AV, Koniaeva EI, Kurchenko VP, Shchekatikhina AS.(PubMed)

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion - The Causes

1. Congestive heart failure
In the study to determine the distribution of pleural effusion between the right and left hemithorax in patients with uncomplicated congestive heart failure, and whether left-sided pleural effusion actually constitutes an atypical distribution in congestive heart failure, indicated that there were bilateral pleural effusions of roughly equal size on each side in 36, there were bilateral pleural effusions larger on the left side than the right in 26, and there were isolated left-sided pleural effusions in 15. The difference was not statistically significant (chi2 = 0.316; P < or = 1.0)(18).
2. Pneumonia
According to the Universidade Federal do Espírito Santo, Vitória, in a a retrospective observational study involving 121 patients with CAP/PPE hospitalized in a tertiary referral hospital between 2000 and 2008, the prevalence of M. pneumoniae-related CAP/PPE was 12.75%. Although the disease was milder than that caused by other microorganisms, its course was longer. Our data suggest that M. pneumoniae-related CAP and PPE in children and adolescents should be more thoroughly investigated in Brazil(19).
3. Liver disease (cirrhosis) and chronic renal disease
There is a report of a 59-year-old man treated with hemodialysis for liver cirhhosis and chronic kidney disease developed right pleural effusion and ascites, according to the study by Takasago Municipal Hospital(20).
4. Primary systemic amyloidosis
According to the study by the Boston University School of Medicine, large, recurrent pleural effusions in systemic amyloidoses are rare but clinically challenging events predominantly affecting patients with primary systemic amyloidosis(21).
5. Nephrotic syndrome
Nephrotic syndrome is a condition of kidney damage with symptoms of protein in the urine, low blood protein levels, high cholesterol levels, high triglyceride levels, etc. According to the study by the, The occurrence of the nephrotic syndrome during mycosis fungoide is very unusual, but there is a report of a rare case of mycosis fungoide revealed by hydrops related to nephrotic syndrom in a 37-year old male patient. He has been admitted to intensive care unit because of a breathing distress and a hydrophobs. Whole body computed tomography scan revealed bilateral axillary, cervical lymph nodes, tumoral infiltration of the subcutaneous tissue in the cervicothoracic and abdominal regions, multiples bilateral pulmonary metastasis, bilateral pleural effusion, and abdominal effusion; the kidneys were normal(22).
6. Surgery
There is a report of 2 cases with unusual "complications" after pacemaker implantation. One patient developed hemorrhagic pleural and 1 patient pericardial effusion. Both manifestations of hemorrhage were felt to be due to complications in relation to the pacemaker implantation(23).
7. Tumors
According to the study by the, Pneumothorax and pleural effusion can occur after radiofrequency (RF) ablation in patients with lung tumors(24).
8. Pulmonary embolism
There is a report of a case of hypertensive 58-year-old woman with hepatic nodules presented dyspnea and pleural effusion one week after an episode of pulmonary embolism(25).
9. Lupus
In the prospective study of 54 patients with pleural effusion (12 lupus pleuritis, seven parapneumonic effusion, 26 malignancy-associated pleural effusions, nine transudative effusions) was performed. ANA at a titer of ≥1, 160 were found in 11 of 12 lupus pleuritis samples, and in four of 42 pleural effusions from non-systemic lupus erythematosus (SLE) patients. The pleural effusion ANA at a titer of ≥1, according to the study by Chiang Mai University(26).
10. Systemic diseases
Despite the low incidence (around 1%) of pleural effusions caused by systemic diseases, more often connective tissue diseases, such as rheumatoid arthritis or systemic lupus erythematosus, may present with this(27)
11. Infections
In the study to investigate whether pleural fluid concentrations of biomarkers for bacterial infection, namely triggering receptor expressed on myeloid cells (sTREM-1), procalcitonin (PCT), lipopolysaccharide-binding protein (LBP) and C-reactive protein (CRP), might identify infectious effusions and discriminate between complicated (CPPEs) and uncomplicated parapneumonic effusions (UPPEs) with Stored pleural fluid samples from 308 patients with different causes of pleural effusion were used to measure the four biomarkers indicated that the area under the curve for distinguishing infectious (parapneumonics and tuberculosis) from noninfectious effusions was 0.87 for CRP, 0.86 for sTREM-1, 0.57 for PCT and 0.87 for LBP. Regarding the discrimination of nonpurulent CPPE versus UPPE, a multivariate analysis found that pleural fluid glucose or =17 microg x mL(-1) and CRP > or =80 mg x L(-1) were the best parameters. Individually, none of the new biomarkers achieved better performance characteristics than pH, glucose or lactate dehydrogenase in labelling CPPE(27a).

The Best smoothie of Green Tea, Orange and Peanut for Prevention and Treatment of Cervical myomas

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of cervical myomas
Yield: 2 servings (about 8 ounces each)
1/2 cup peanut
1 orange
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed

3. Serve immediately

The finding of a natural source for reduced risk and treatment of cervical polyps to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Cervical myomas (3%-9% of all leiomyomas) are benign tumor arising from the lower uterine segment. The myoma may bleed, become infected, interfere with urinating, or cause pain during sexual intercourse. Surgery may be the best option but it also induced blood loss, and distortion of the anatomy of the vital neighboring structures in the pelvic cavity, if myomas are closer to other organs such as the bladder, ureter, and rectum(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its Epigallocatechin gallate (EGCG), the major catechin in green tea has shown to to inhibit key pathways of tumor growth(2)

According to the Oncology and Radiobiology, NAS of Ukraine, polyphenol extracts from green tea, red wine lees and/or lemon peel alone used conjuction with antitumor drugs effectively ameliorated the growth of different transplanted tumors in animal model(3).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in peanuts, also expressed strongly anti tumors effect in experimental animal(3). According to the The University of Tokyo, resveratrol (3, 5, 4'-trihydroxystilbene) is a phytoalexin contained in a variety of plants exhibited anti tuome effect through suppressed cell proliferation, induced apoptosis and suppressed the metastasis and cell invasion through suppress cell proliferation, induce apoptosis and suppress the metastasis and cell invasion through regulating cellular mechanisms(4), including cell cycle arrest and apoptosis in intestinal smooth muscle cells.(5).

Vitamin C, a water soluble vitamin, found abundantly in orange manifested anti tumor activities through expression of strongest activator of phagocytosis and antibody formation when used conjunction with glucan, resveratrol(6).

According to the Seoul National University College of Medicine, vitamin C also increases the susceptibility of tumor cells to anti-Fas Abs and the expression of Fas (CD95) and MHC class I on tumor cells, in dose-depend manner(7).

The effectiveness of Green Tea, Orange and Peanut may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of Cervical myomas with little or no adverse effects.

Women who are at increased risk of . Otherwise, intake of Cervical myomas due to family history,..... should drink at least 1 serving daily. Women with Cervical myomas should drink as much as they can, depending to digestive toerlation.

Life style and dietary patter change are recommended.

References

(1) Handling cervical myomas by Patel P1, Banker M, Munshi S, Bhalla A.(PubMed)

(2) Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate by Khan N1, Afaq F, Saleem M, Ahmad N, Mukhtar H.(PubMed)

(3) Green tea, red wine and lemon extracts reduce experimental tumor growth and cancer drug toxicity by Zaletok SP1, Gulua L2, Wicker L3, Shlyakhovenko VA1, Gogol S1, Orlovsky O1, Karnaushenko OV1, Verbinenko A1, Milinevska V1, Samoylenko O1, Todor I1,Turmanidze T2.(PubMed)

(4) Anti-tumor effects and cellular mechanisms of resveratrol by Han G1, Xia J, Gao J, Inagaki Y, Tang W, Kokudo N.(PubMed)

(5) Resveratrol causes cell cycle arrest, decreased collagen synthesis, and apoptosis in rat intestinal smooth muscle cells by Garcia P1, Schmiedlin-Ren P, Mathias JS, Tang H, Christman GM, Zimmermann EM.(PubMed)

(6) Combination of glucan, resveratrol and vitamin C demonstrates strong anti-tumor potential by Vetvicka V1, Vetvickova J.(PubMed)

(7) The Anti-tumor Activity of Vitamin C via the Increase of Fas (CD95) and MHC I Expression on Human Stomach Cancer Cell Line, SNU1 by Yu Y1, Bae S, Kim H, Kim Y, Chu NB, Chu NK, Kang JS, Lee WJ.(PubMed)

The Tasty Smoothie of Grape, Curcumin and Peppermint Tea for Prevention and Treatment of Toxic Hepatitis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The finding of a natural source for treatment of Toxic Hepatitis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Toxic liver is na inflammatory liver diseases caused by accumulation of chemicals, including drugs, medication, environment toxins. etc.....

The Smoothie for reduced risk and treatment of Toxic Hepatitis
Yield: 2 servings (about 8 ounces each)
1 1/2 cup grapes
1 tsp curcumin
1/2 cup peppermint herbal tea

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding the natural ingredient for prevention and treatment of Toxic Hepatitis to replace the medication from conventional has been facing many obstacles. Many initially potentially therapeutic values working in animal studies does not produce the same effectiveness in human trials.

Recent studies suggested that grape(1) and turmeric(4) and peppermint(7) may have a potential effect on treatment of patient with Toxic Hepatitis .

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape and blueberry associated to reduce risk and treatment of Toxic Hepatitis, according to the University of Rio Grande do Sul (PUCRS(1).In animal study, resveratrol effectively attenuated α-Naphthylisothiocyanate (ANIT) iinduced acute cholestasis and liver injury, through suppression of neutrophil infiltration induced by inflammation, as well as upregulation of expression of hepatic transporters and enzymes(2).

In acetaminophen-induced toxic liver, treatment with RES significantly induced SIRT1 (cell regulation)and then negatively regulated p53, antigne signaling to induce cell proliferation-associated proteins(3).

Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. Its antioxidant, curcumin exhibited liver protective effects(4)(5) through attenuated proinflammatory cytokines(5) and improved antioxidant enzymes status(4).
In rat study, RES exhibited anti D-GalN/LPS-induced liver damage by by the enhancing antioxidant defense system, attenuating mitochondrial dysfunction and inhibiting apoptosis, the joint study lead by the Nanjing Agricultural University suggested(6).

Dr. Bulku E and professors at the Manchester College School of Pharmacy, insisted the effectiveness of RES in protective against chemicals induced liver damage may be due its function in modulating multiple pro-apoptotic and anti-apoptotic signaling pathways(7).

Silymarin, a phytochemical in the class of phenolic acids, found abundantly in peppermint exhibited hepatoprotective effect against antituberculosis drug-induced liver injury, through promotion of superoxide dismutase restoration(8).

In isonicotinylhydrazine-induced hepatotoxicity in rabbit model, combined isoniazid and silymarin significantly improved serum billirubin and serum alanine transaminase(9).

Dr. Gillessen A and colleagues said, "Silymarin is a safe and efficacious treatment option for patients with elevated liver enzymes. A benefit in terms of liver-related symptoms as well as quality of life and performance was demonstrated already after 2 months of treatment."(10).

The effectiveness of Grape, Curcumin and Peppermint Tea may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Toxic Hepatitis with little or no adverse effects.

People who are at high risk of Toxic Hepatitis due to medication, environment factors, .... should drink at least one serving daily and women with Toxic Hepatitis should drink the smoothie as much as they can, depending to digestive toleration.

Life style and dietary pattern(reduced intake of bad cholesterol)change are recommended.

All Forms of Arthritis are Curable

You Can Eliminate Osteoarthritis

By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Protective effects of resveratrol on hepatotoxicity induced by isoniazid and rifampicin via SIRT1 modulation by Nicoletti NF1, Rodrigues-Junior V, Santos AA Jr, Leite CE, Dias AC, Batista EL Jr, Basso LA, Campos MM, Santos DS, Souto AA.(PubMed)

(2) Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms by Wang T1, Zhou ZX2, Sun LX3, Li X3, Xu ZM3, Chen M3, Zhao GL3, Jiang ZZ1, Zhang LY4.(PubMed)

(3) Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathwaysby Wang Y1, Jiang Y1, Fan X1, Tan H1, Zeng H1, Wang Y1, Chen P2, Huang M1, Bi H3.(PubMed)

(4) Hepatoprotective effects of curcumin against diethyl nitrosamine induced hepatotoxicity in albino rats by Kadasa NM1, Abdallah H, Afifi M, Gowayed S.(PubMed)

(5)Curcumin inhibits activation of TRPM2 channels in rat hepatocytes. by Kheradpezhouh E1, Barritt GJ2, Rychkov GY3.(PubMed)

(6) Curcumin attenuates D-galactosamine/lipopolysaccharide-induced liver injury and mitochondrial dysfunction in mice by Zhang J1, Xu L1, Zhang L1, Ying Z1, Su W1, Wang T2.(PubMed)

(7) Curcumin exposure modulates multiple pro-apoptotic and anti-apoptotic signaling pathways to antagonize acetaminophen-induced toxicity by Bulku E1, Stohs SJ, Cicero L, Brooks T, Halley H, Ray SD.(PubMed)

(8) A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury by Luangchosiri C1, Thakkinstian A2, Chitphuk S3, Stitchantrakul W3, Petraksa S1, Sobhonslidsuk A4,5.(PubMed)

(9) The hepatoprotective role of Silymarin in isoniazid induced liver damage of rabbits by Jahan S1, Khan M1, Imran S1, Sair M1.(PubMed)

(10) [Effect of silymarin on liver health and quality of life. Results of a non-interventional study].[Article in German] by Gillessen A, Herrmann WA, Kemper M, Morath H, Mann K.(PubMed)

The Delicious Cooked Spinach, Tomato, Orange and Sweet Potato for Prevention and Treatment of Preeclampsia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of preeclampsia

Yield: 2 servings (about 8 ounces each)
1/2 cup cooked spinach
1/2 cup tomato
1/2 cup sweet potato
1 cup orange juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of preeclampsia has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.
Preeclampsia is a condition in pregnancy with expression of high blood pressure, sometimes with fluid retention and proteinuria. According to the joint study led by Bharati Vidyapeeth University women with PE are associated to increase oxidative stress right from 16 to 20 weeks of gestation(1). Study suggested the implication of concentrations of increased free fatty acid (FFA), and decreased activity of antioxidant enzyme in placenta may contribute to oxidative damage levels(2) in placental mitochondria in women with PE)(3). Levels of vitamin C(orange) and E(Sweet Potato) were significantly negative for overall preeclampsia(4).

Dr. Basaran A and professors at the ACIBADEM Kayseri Hospital said, "supplementation of vitamins C and E(May be used) for the prevention of preeclampsia or other pregnancy induced hypertensive disorders"(5).

The effectiveness of Cooked Spinach, Tomato, Orange and Sweet Potato may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for prevention and treatment of Preeclampsia with little or no adverse effects.

People who are at high risk of Preeclampsia due to family history,..... should drink at least one serving daily and people with Preeclampsia should drink the smoothie as much as they can, depending to digestive toleration.
Life style and dietary patter change are recommended.

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Refeneces
(1) Increased oxidative stress from early pregnancy in women who develop preeclampsia By D'Souza V1, Rani A1, Patil V1, Pisal H1, Randhir K1, Mehendale S2, Wagh G2, Gupte S3, Joshi S1.(PubMed)
(2) [Relationships between concentrations of free fatty acid in serum and oxidative-damage levels in placental mitochondria and preeclampsia].[Article in Chinese] by Yan JY1, Xu X.(PubMed)
(3) The association between maternal antioxidant levels in midpregnancy and preeclampsia. by Cohen JM1, Kramer MS2, Platt RW2, Basso O3, Evans RW4, Kahn SR5.(PubMed)
(4) Maternal Antioxidant Levels in Pregnancy and Risk of Preeclampsia and Small for Gestational Age Birth: A Systematic Review and Meta-Analysis by Cohen JM1, Beddaoui M2, Kramer MS3, Platt RW3, Basso O4, Kahn SR1.(PubMed)
(5) Combined vitamin C and E supplementation for the prevention of preeclampsia: a systematic review and meta-analysis by Basaran A1, Basaran M, Topatan B.(PubMed)

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