Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Rheumatoid Arthritis
Rheumatoid Arthritis is defined a chronic disorder as a result of inflammation, affecting mostly the flexible (synovial) joints and tissues and organs in the body. The disease affects more women than men and generally occurs after the ages of 40, causing diminished quality of life of many elders(1). According to CDC, Musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions(2). Rheumatoid Arthritis can induced bone loss through elevating bone resorption without increasing bone formation(4). A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes(4a).
The Treatment
B. Treatment in herbal and traditional Chinese medicine
B.9. The herbal formulas in herbal and traditional Chinese medicine
Rheumatoid arthritis (RA) is a common worldwide public health problem especially in China, many RA formula has been used in the clinic and some of these TCM formulas have been existed over thousands of years in ancient China(388) with potential mechanisms such as inhibited osteoclast proliferation, suppressed fibroblast, decreased the expression of inflammatory cytokines, blocking signal pathways, etc.).
6. Other formula used for treatment of RA may include
6.1. SKI306X, is a herbal formula containing Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK)used to relieve pain associated with an anti-inflammatory and analgesic effect, as well as delay the destruction of cartilage in rheumatoid arthritis(403).
6.2. Wen Luo Yin (WLY) used in traditional Chinese formula for treatment of scattering cold pathogen, draining dampness, freeing the flow of network vessels and relieving pains may be a next pharmaceutical therapeutic agent for treaament of RA as it inhibited inflammation, pannus formation, cartilage and bone destruction of inflamed joints in CIA rat model(402).
6.3. Wei-Ling-Xian, another anti-arthritic herbal formula may also be effective for treatment of RA due to its phytochemical clematichinenoside (AR-6)in inhibition of pro inflammatory cytokines(403).
6.4. Liang Miao San, the herbal formual composed of the herbs Rhizoma Atractylodis (Cangzhu) and Cotex Phellodendri (Huangbai), is another traditional Chinese medicine formula for rheumatoid arthritis (RA) treatment through expression of differential anti-inflammatory activities of its phytochemical sinomenine by modulating distinct intracellular signaling pathways in RA(404).
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) 8 Areas of Age-Related Change(NIH)
(2) Arthritis-Related Statistics(CDC)
(3) Valgus deformities of the feet and characteristics of gait in patients who have rheumatoid arthritis by Keenan MA1, Peabody TD, Gronley JK, Perry J.(PubMed)
(4) Serum Sclerostin Level Among Egyptian Rheumatoid Arthritis Patients: Relation to Disease Activity ,Bone Mineral Density and Radiological Grading by Mehaney DA, Eissa M, Anwar S, El-Din SF(PubMed)
(4a) Death rates and causes of death in patients with rheumatoid arthritis: a population-based study by Sihvonen S1, Korpela M, Laippala P, Mustonen J, Pasternack A(PubMed)
(402) Wen Luo Yin inhibits angiogenesis in collagen-induced arthritis rat model and in vitro by Liu C1, Kong X, Li X, Guo W, Zhang C, Sun Y, Su X, Liu X, Lu A, Lin N(PubMed)
(403) Anti-arthritic effects of clematichinenoside (AR-6) on PI3K/Akt signaling pathway and TNF-α associated with collagen-induced arthritis by Han W1, Xiong Y, Li Y, Fang W, Ma Y, Liu L, Li F, Zhu X.(PubMed)
(404) Anti-inflammatory activities of Chinese herbal medicine sinomenine and Liang Miao San on tumor necrosis factor-α-activated human fibroblast-like synoviocytes in rheumatoid arthritis by Chen DP1, Wong CK, Leung PC, Fung KP, Lau CB, Lau CP, Li EK, Tam LS, Lam CW.(PubMed)
Sunday, May 22, 2016
The Smoothie of Green Tea, Blueberry, Grape, Peanut and Curcumin for Treatment of Minimal mesangial glomerulonephritis induced by SLE
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The smoothie for prevention and treatment of Minimal mesangial glomerulonephritis induced by Systemic lupus erythematosus (SLE)
Yield: 2 servings (about 8 ounces each)
1/ 4 cup Blueberry
1 cup grape
1/4 cup peanut
1/4 tsp curcumin(optional)
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
The finding of a natural source for treatment of Malarial nephropathy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.
Minimal mesangial glomerulonephritis is a type of glomerulonephritis, affecting 10% to 25% of patients with lupus nephritis SLE, a disease of the autoimmune system.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to Kyushu University, chronic drinking of tea may attenuate the risk of Systemic lupus erythematosus (SLE)(1)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
The smoothie for prevention and treatment of Minimal mesangial glomerulonephritis induced by Systemic lupus erythematosus (SLE)
Yield: 2 servings (about 8 ounces each)
1/ 4 cup Blueberry
1 cup grape
1/4 cup peanut
1/4 tsp curcumin(optional)
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately
The finding of a natural source for treatment of Malarial nephropathy has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.
Minimal mesangial glomerulonephritis is a type of glomerulonephritis, affecting 10% to 25% of patients with lupus nephritis SLE, a disease of the autoimmune system.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to Kyushu University, chronic drinking of tea may attenuate the risk of Systemic lupus erythematosus (SLE)(1)
Major phytochemical constituent isolated from green tea, in National Defense Medical Center study, expressed the prophylactic effects on lupus nephritis in prevented proteinuria, renal function impairment, and severe renal lesions through antioxidant and free radical scavenging and anti pro inflammatory activities(2).
Furthermore, the antioxidant also manifested the cisplatin-induced nephrotoxicity is associated with increased oxidative stress and inflammatory cytokines in the kidney, including inhibiting NF-kappaB, the pro inflammatory pathway(3).
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in grape, blueberry and peanuts, may also display anti Minimal mesangial glomerulonephritis induced by Systemic lupus erythematosus (SLE) through its immune-modulated effects(5). According to the joint study led by the Peking Union Medical College and Chinese Academy of Medical Sciences, resveratrol exhibited protective effects in pristane-induced lupus mice via anti-inflammation and immune-regulatory properties(4).
Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia. The herb has been used in trditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc. its chemical constituent curcumin exhibited anti SLE effects through maintaining the balance between T helper 17 (Th17) and regulatory T cells (Treg)(6).
According to the University of Chicago, curcumin increased the expression of IgG deposits in protection against altered the transport of immune complexes leading to an increase in IgG deposits which could induce inflammatory pathways thereby leading to worsening of the disease(7).
The smoothie of Green Tea, Blueberry, Grape, Peanut and Curcumin may hold a key in further studies in production of effective natural ingredients for prevention and treatment of any type of Minimal mesangial glomerulonephritis induced by SLEwithout inducing adverse effects.
People who are at increased risk of any of Minimal mesangial glomerulonephritis induced by SLE, due to family history, weaken immunity... should drink at least one cup daily. People with Minimal mesangial glomerulonephritis induced by SLE, should drink no more than 4 servings daily, depending to the digestive toleration.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
According to the University of Chicago, curcumin increased the expression of IgG deposits in protection against altered the transport of immune complexes leading to an increase in IgG deposits which could induce inflammatory pathways thereby leading to worsening of the disease(7).
Furthermore, oral administration of turmeric supplementation can decrease proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis, the Shiraz University of Medical Sciences suggested(8).
The smoothie of Green Tea, Blueberry, Grape, Peanut and Curcumin may hold a key in further studies in production of effective natural ingredients for prevention and treatment of any type of Minimal mesangial glomerulonephritis induced by SLEwithout inducing adverse effects.
People who are at increased risk of any of Minimal mesangial glomerulonephritis induced by SLE, due to family history, weaken immunity... should drink at least one cup daily. People with Minimal mesangial glomerulonephritis induced by SLE, should drink no more than 4 servings daily, depending to the digestive toleration.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(1) Modifying effect of N-acetyltransferase 2 genotype on the association between systemic lupus erythematosusand consumption of alcohol and caffeine-rich beverages by Kiyohara C1, Washio M, Horiuchi T, Asami T, Ide S, Atsumi T, Kobashi G, Takahashi H, Tada Y; Kyushu Sapporo SLE (KYSS) Study Group.(PubMed)
(2) Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation by Tsai PY1, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, Hua KF, Chang WL, Huang JJ, Yang SS, Chen A.(PubMed)
(3) Epigallocatechin-3-gallate activates Nrf2/HO-1 signaling pathway in cisplatin-induced nephrotoxicity in rats by Sahin K1, Tuzcu M, Gencoglu H, Dogukan A, Timurkan M, Sahin N, Aslan A, Kucuk O.(PubMed)
(4) Resveratrol possesses protective effects in a pristane-induced lupus mouse model by Wang ZL1, Luo XF1, Li MT1, Xu D1, Zhou S1, Chen HZ2, Gao N1, Chen Z1, Zhang LL1, Zeng XF1.(PubMed)
(5) [Effect of resveratrol on the activation of murine CD4(+);T lymphocytes].[Article in Chinese]by Wang Z1, Zeng X, Li M, Luo X.(PubMed)
(6) Treatment of low doses curcumin could modulate Th17/Treg balance specifically on CD4+ T cell cultures ofsystemic lupus erythematosus patients by Handono K1, Pratama MZ2, Endharti AT3, Kalim H2.(PubMed)
(7) Curcumin aggravates CNS pathology in experimental systemic lupus erythematosus by Foxley S1, Zamora M, Hack B, Alexander RR, Roman B, Quigg RJ, Alexander JJ.(PubMed)
(8) Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study by Khajehdehi P1, Zanjaninejad B, Aflaki E, Nazarinia M, Azad F, Malekmakan L,Dehghanzadeh GR.(PubMed)
Most Common Diseases of 50plus: Diabetes(The Articles) --- When Dining Out
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
If you are diabetic, the chance that you are overweight and this increase the
chance of high cholesterol and high blood pressure. So, to control the
glucose in your blood stream, you might want to try high protein diet
together with fighting cholesterol and high blood pressure natural remedies.
Traditionally, diabetes is viewed as a failure of the pancreas to release
enough insulin for sugar metabolism. People with diabetes has grown
increasingly worse over last 10 years. The escalation in diabetes corresponds
to rise in heart disease, because of over weight, poor diet and lack of
exercise.
We eat out because it's easy, it's quick, and it's fun. But is it healthy? For type II diabetics, if you only eating out once a month, there is no need to worry about what you eat, but if it is 2 or 3 times a week, making good choices of foods is critical to your nutrition as well as blood sugar. Food in the restaurants contain more salt, saturated fat and I tend to eat more than we would at home.
Here are some tips on avoiding the traps when dining out:
1. Do not go out with an empty stomach
Eat a light healthy breakfast and lunch before you go. This will take the edge off your appetite and you will be less likely to over-eat.
2 Start with bread:
Ask the server if they have whole grain bread, because it will be digested slowly and gradually turned into glucose in your bloodstream. Also bread makes you feel full and you will be less likely to over-eat.
3. Drinks:
Water is the best choice in dining out. Most restaurants today offer free cool water for all customers, if not you can still ask for it. If you really want to drink, limiting yourself to 1-2 glasses of alcohol.
4. Remember that your meals should contain carbohydrates, proteins and vegetables:
Pick foods from menus that give you all three of the above components.
5. Eat slowly:
Take time to enjoy your foods and talk to your friends, eating slowly will help you stomach digest foods more slowly, resulting in glucose entering the bloodstream more slowly giving time for insulin to do it's job.
6. Order your food slowly:
Do not order all your foods at once. Otherwise, you will be likely to over-eat
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
chance of high cholesterol and high blood pressure. So, to control the
glucose in your blood stream, you might want to try high protein diet
together with fighting cholesterol and high blood pressure natural remedies.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Traditionally, diabetes is viewed as a failure of the pancreas to release
enough insulin for sugar metabolism. People with diabetes has grown
increasingly worse over last 10 years. The escalation in diabetes corresponds
to rise in heart disease, because of over weight, poor diet and lack of
exercise.
We eat out because it's easy, it's quick, and it's fun. But is it healthy? For type II diabetics, if you only eating out once a month, there is no need to worry about what you eat, but if it is 2 or 3 times a week, making good choices of foods is critical to your nutrition as well as blood sugar. Food in the restaurants contain more salt, saturated fat and I tend to eat more than we would at home.
Here are some tips on avoiding the traps when dining out:
1. Do not go out with an empty stomach
Eat a light healthy breakfast and lunch before you go. This will take the edge off your appetite and you will be less likely to over-eat.
2 Start with bread:
Ask the server if they have whole grain bread, because it will be digested slowly and gradually turned into glucose in your bloodstream. Also bread makes you feel full and you will be less likely to over-eat.
3. Drinks:
Water is the best choice in dining out. Most restaurants today offer free cool water for all customers, if not you can still ask for it. If you really want to drink, limiting yourself to 1-2 glasses of alcohol.
4. Remember that your meals should contain carbohydrates, proteins and vegetables:
Pick foods from menus that give you all three of the above components.
5. Eat slowly:
Take time to enjoy your foods and talk to your friends, eating slowly will help you stomach digest foods more slowly, resulting in glucose entering the bloodstream more slowly giving time for insulin to do it's job.
6. Order your food slowly:
Do not order all your foods at once. Otherwise, you will be likely to over-eat
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to General health http://kylejnorton.blogspot.ca/p/general-health.html
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Phytochemicals In Foods: The effects of Dithiolthiones(Isothiocyanates)
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color. Phytochemicals may be next potential sources of new medicine for treatment of diseases with little or no side effects.
Dithiolthiones(Isothiocyanates)are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
The Health effects of Dithiolthiones include
1. Anti acetaminophen hepatotoxicity
In the investigation of Anethol dithiolthione (ADT), usually prescribed as a choleretic drug, given orally 1 hour prior to acetaminophen (AAP) (450 mg/kg intraperitoneally) in Swiss female mice, found that ADT exhibited an hepatoprotective potency at doses as low as 10 mg/kg relative to serum aminotransferase activities and hepatic glutathione related enzyme system (glutathione reductase, peroxidase, transferase), according to "Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice" by Warnet JM, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR.(1)
2. Chemopreventive efficacy
in the observation of two exposure regimens used to compare the efficacies of early (Regimen-A) versus late (Regimen-B) intervention in prevention of lung tumorigenesis in A/J mice, indicated that Evaluation of lung tumor multiplicity following exposure to oltipraz showed that oltipraz inhibited the tumor development in a dose-dependent manner (10-100 mg/m(3)) with inhibition ranging from 37 to 53% in Regimen A and 51% in Regimen B, when compared with the B[a]P group. Analysis of the tumor incidence showed that 81.5% of the animals had 10 or more tumors in the B[a]P group, whereas, in oltipraz exposure groups, there was a significant decrease in Regimen A (24-36%) and in Regimen B (42%), according to "The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model" by Sharma S, Gao P, Steele VE.(2)
3. Detoxication of xenobiotics
In the testing The dithiolthiones, oltipraz, ADT, 116L and 129L, in mice and in rats, oltipraz. Intragastric administration of dithiolthiones (oltipraz, ADT or 116L; two doses each of 1 g/kg body weight) found that Dithiolthiones present in cabbage may play a role in the protective actions of diets high in vegetables against the toxic actions of xenobiotics, according to "Biochemical effects of dithiolthiones' by Ansher SS, Dolan P, Bueding E.(3)
4. Antioxidants
In the examination of the role of glutathione (GSH) in the regulation of this adhesion phenomenon and in the increased tyrosine phosphorylation induced by ROS, found that ADT reduced both PMN adhesion to ROS-stimulated human umbilical vein endothelial cells (HUVEC) and tyrosine phosphorylation of p125FAK and paxillin. ADT increased redox status by increasing intracellular GSH content in oxidized cells. These results show that GSH can reverse the effect of oxidation on tyrosine kinase activation and phosphorylation, and thus plays an important role in cell signaling. They also confirm the antioxidant activity of ADT, according to "Anethole dithiolethione regulates oxidant-induced tyrosine kinase activation in endothelial cells" by Ben-Mahdi MH, Gozin A, Driss F, Andrieu V, Christen MO, Pasquier C.(4)
5. Aflatoxin B1 contamination
In the study of the influence of oltipraz and a second dithiolthione, (1,2) dithiolo (4,3-c)-1,2-dithiole-3,6 dithione (DDD) on bovine hepatic aflatoxin B1 biotransformation, found that Oltipraz inhibited aflatoxin B1 metabolism as no aflatoxin M1 and no aflatoxin B1-dihydrodiol, the second metabolite found in bovine hepatocytes, was formed. DDD did not significantly inhibit aflatoxin B1 metabolism. It could be demonstrated that the inhibition of aflatoxin B1 metabolism was due to the inhibition of several cytochrome P450 enzyme activities by oltipraz. In contrast, DDD inhibited only ethoxyresorufin O-deethylation activity, according to "Inhibition of aflatoxin M1 production by bovine hepatocytes after intervention with oltipraz" by Kuilman ME, Maas RF, Woutersen-van Nijnanten FM, Fink-Gremmels J.(5)
6. Cancer prevention
In the investigation of The critical role of the glutathione S-transferase (GST) and their importance in cancer prevention and susceptibility, clinical studies revealed that the GST activity of blood lymphocytes from individuals with either a personal or family history of colorectal cancer or a personal history of colon polyps was decreased significantly when compared to that of healthy controls. Phase 1 clinical evaluation of oltipraz has demonstrated its ability to induce GST activity as well as the level of transcripts encoding gamma-glutamylcysteine synthetase (gamma-GCS) and DT-diaphorase in the colon mucosa of individuals at increased risk for colorectal cancer. The observed correlation between the posttreatment response in blood lymphocytes and colon mucosa suggested that blood lymphocytes may be used in future trials as a surrogate biomarker of the responsiveness of colon tissue to chemopreventive regimens, according to "Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response" by Clapper ML, Szarka CE.(6)
7. Anti nephrotoxicity
in the determination of s the effects of ADT on hexachloro-1,3-butadiene (HCBD)-induced nephrotoxicity in the rat and the mechanism of its action, found that ADT protects rats against HCBD-induced nephrotoxicity by a mechanism that does not involve the modulation of HCBD conjugation with liver GSH, nor the modulation of the kidney NPSH level and beta-lyase activity. The mechanism of protection conferred to rats by an ADT pretreatment against HCBD-induced nephrotoxicity appears to take place in the kidney at a step beyond the generation of ultimate toxic metabolites derived from PCBC, according to 'Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthioneagainst hexachloro-1,3-butadiene-induced nephrotoxicity" by Bouthillier L, Charbonneau M, Brodeur J.(7)
8. Inhibition of platelet aggregation
in the investigation of Anethole dithiolthione (ADT) (10 mumol/l) inhibition of platelet aggregation and the formation of thromboxane (Tx)B2 in plasma in response to adenosine diphosphate (ADP), epinephrine and arachidonic acid (AA), indicated that ADT had no additive effect on the inhibition of thrombin-induced platelet aggregation by acetylsalicylic acid. ADT was a more effective inhibitor of AA-induced platelet aggregation than butylated hydroxytoluene. ADT inhibited the release of 3H-AA from platelet phospholipids in response to ADP and collagen. It is suggested that ADT inhibits platelet aggregation by inhibiting thromboxane synthesis and preventing AA release, according to "Effect of anetholedithiolthione on human platelet aggregation" by Selley ML, McGuiness JA, Bartlett MR, Ardlie NG.(8)
9. Early colon carcinogenesis
in the study of the effect of dietary oltipraz on liver and colonic mucosal enzymes and DNA adducts in evaluating the modulating role of this agent during the early period of azoxymethane (AOM)-induced carcinogenesis, showed that dietary oltipraz enhances the colonic and liver glutathione S-transferase activity and reduced the formation of DNA adducts. In addition, dietary oltipraz modulates liver and colonic ODC and TPK activities that have been shown to play a role in tumor promotion, according to "Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats" by Rao CV, Nayini J, Reddy BS.(9)
10. Lipid peroxidation
in the observation of the drug anisyldithiolthione (ADT) acted as a good inhibitor of lipid peroxidation induced in rat liver microsomes either chemically by FeSO4 and reducing agents (cysteine or ascorbate) or enzymatically by NADPH and CC14, showed that at doses as low as 5 mg per kg it completely suppressed ethane exhalation by acetaminophen-intoxicated mice and also protected them very efficiently against mortality caused by acetaminophen overdose. The inhibitory effect of ADT toward lipid peroxidation seems to be linked to the presence of itsdithiolthione function, according to "A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione" by Mansuy D, Sassi A, Dansette PM, Plat M.(10)
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to OfferSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/2780509
(2) http://carcin.oxfordjournals.org/content/27/8/1721.abstract
(3) http://www.ncbi.nlm.nih.gov/pubmed/3744194
(4) http://www.ncbi.nlm.nih.gov/pubmed/11213483
(5) http://www.ncbi.nlm.nih.gov/pubmed/10682385
(6) http://www.ncbi.nlm.nih.gov/pubmed/9679568
(7) http://www.ncbi.nlm.nih.gov/pubmed/8685901
(8) http://www.ncbi.nlm.nih.gov/pubmed/1497692
(9) http://www.ncbi.nlm.nih.gov/pubmed/2020672
(10) http://www.ncbi.nlm.nih.gov/pubmed/3964266
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color. Phytochemicals may be next potential sources of new medicine for treatment of diseases with little or no side effects.
Dithiolthiones(Isothiocyanates)are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
The Health effects of Dithiolthiones include
1. Anti acetaminophen hepatotoxicity
In the investigation of Anethol dithiolthione (ADT), usually prescribed as a choleretic drug, given orally 1 hour prior to acetaminophen (AAP) (450 mg/kg intraperitoneally) in Swiss female mice, found that ADT exhibited an hepatoprotective potency at doses as low as 10 mg/kg relative to serum aminotransferase activities and hepatic glutathione related enzyme system (glutathione reductase, peroxidase, transferase), according to "Protective effect of anethol dithiolthione against acetaminophen hepatotoxicity in mice" by Warnet JM, Christen MO, Thevenin M, Biard D, Jacqueson A, Claude JR.(1)
2. Chemopreventive efficacy
in the observation of two exposure regimens used to compare the efficacies of early (Regimen-A) versus late (Regimen-B) intervention in prevention of lung tumorigenesis in A/J mice, indicated that Evaluation of lung tumor multiplicity following exposure to oltipraz showed that oltipraz inhibited the tumor development in a dose-dependent manner (10-100 mg/m(3)) with inhibition ranging from 37 to 53% in Regimen A and 51% in Regimen B, when compared with the B[a]P group. Analysis of the tumor incidence showed that 81.5% of the animals had 10 or more tumors in the B[a]P group, whereas, in oltipraz exposure groups, there was a significant decrease in Regimen A (24-36%) and in Regimen B (42%), according to "The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model" by Sharma S, Gao P, Steele VE.(2)
3. Detoxication of xenobiotics
In the testing The dithiolthiones, oltipraz, ADT, 116L and 129L, in mice and in rats, oltipraz. Intragastric administration of dithiolthiones (oltipraz, ADT or 116L; two doses each of 1 g/kg body weight) found that Dithiolthiones present in cabbage may play a role in the protective actions of diets high in vegetables against the toxic actions of xenobiotics, according to "Biochemical effects of dithiolthiones' by Ansher SS, Dolan P, Bueding E.(3)
4. Antioxidants
In the examination of the role of glutathione (GSH) in the regulation of this adhesion phenomenon and in the increased tyrosine phosphorylation induced by ROS, found that ADT reduced both PMN adhesion to ROS-stimulated human umbilical vein endothelial cells (HUVEC) and tyrosine phosphorylation of p125FAK and paxillin. ADT increased redox status by increasing intracellular GSH content in oxidized cells. These results show that GSH can reverse the effect of oxidation on tyrosine kinase activation and phosphorylation, and thus plays an important role in cell signaling. They also confirm the antioxidant activity of ADT, according to "Anethole dithiolethione regulates oxidant-induced tyrosine kinase activation in endothelial cells" by Ben-Mahdi MH, Gozin A, Driss F, Andrieu V, Christen MO, Pasquier C.(4)
5. Aflatoxin B1 contamination
In the study of the influence of oltipraz and a second dithiolthione, (1,2) dithiolo (4,3-c)-1,2-dithiole-3,6 dithione (DDD) on bovine hepatic aflatoxin B1 biotransformation, found that Oltipraz inhibited aflatoxin B1 metabolism as no aflatoxin M1 and no aflatoxin B1-dihydrodiol, the second metabolite found in bovine hepatocytes, was formed. DDD did not significantly inhibit aflatoxin B1 metabolism. It could be demonstrated that the inhibition of aflatoxin B1 metabolism was due to the inhibition of several cytochrome P450 enzyme activities by oltipraz. In contrast, DDD inhibited only ethoxyresorufin O-deethylation activity, according to "Inhibition of aflatoxin M1 production by bovine hepatocytes after intervention with oltipraz" by Kuilman ME, Maas RF, Woutersen-van Nijnanten FM, Fink-Gremmels J.(5)
6. Cancer prevention
In the investigation of The critical role of the glutathione S-transferase (GST) and their importance in cancer prevention and susceptibility, clinical studies revealed that the GST activity of blood lymphocytes from individuals with either a personal or family history of colorectal cancer or a personal history of colon polyps was decreased significantly when compared to that of healthy controls. Phase 1 clinical evaluation of oltipraz has demonstrated its ability to induce GST activity as well as the level of transcripts encoding gamma-glutamylcysteine synthetase (gamma-GCS) and DT-diaphorase in the colon mucosa of individuals at increased risk for colorectal cancer. The observed correlation between the posttreatment response in blood lymphocytes and colon mucosa suggested that blood lymphocytes may be used in future trials as a surrogate biomarker of the responsiveness of colon tissue to chemopreventive regimens, according to "Glutathione S-transferases--biomarkers of cancer risk and chemopreventive response" by Clapper ML, Szarka CE.(6)
7. Anti nephrotoxicity
in the determination of s the effects of ADT on hexachloro-1,3-butadiene (HCBD)-induced nephrotoxicity in the rat and the mechanism of its action, found that ADT protects rats against HCBD-induced nephrotoxicity by a mechanism that does not involve the modulation of HCBD conjugation with liver GSH, nor the modulation of the kidney NPSH level and beta-lyase activity. The mechanism of protection conferred to rats by an ADT pretreatment against HCBD-induced nephrotoxicity appears to take place in the kidney at a step beyond the generation of ultimate toxic metabolites derived from PCBC, according to 'Assessment of the role of glutathione conjugation in the protection afforded by anethol dithiolthioneagainst hexachloro-1,3-butadiene-induced nephrotoxicity" by Bouthillier L, Charbonneau M, Brodeur J.(7)
8. Inhibition of platelet aggregation
in the investigation of Anethole dithiolthione (ADT) (10 mumol/l) inhibition of platelet aggregation and the formation of thromboxane (Tx)B2 in plasma in response to adenosine diphosphate (ADP), epinephrine and arachidonic acid (AA), indicated that ADT had no additive effect on the inhibition of thrombin-induced platelet aggregation by acetylsalicylic acid. ADT was a more effective inhibitor of AA-induced platelet aggregation than butylated hydroxytoluene. ADT inhibited the release of 3H-AA from platelet phospholipids in response to ADP and collagen. It is suggested that ADT inhibits platelet aggregation by inhibiting thromboxane synthesis and preventing AA release, according to "Effect of anetholedithiolthione on human platelet aggregation" by Selley ML, McGuiness JA, Bartlett MR, Ardlie NG.(8)
9. Early colon carcinogenesis
in the study of the effect of dietary oltipraz on liver and colonic mucosal enzymes and DNA adducts in evaluating the modulating role of this agent during the early period of azoxymethane (AOM)-induced carcinogenesis, showed that dietary oltipraz enhances the colonic and liver glutathione S-transferase activity and reduced the formation of DNA adducts. In addition, dietary oltipraz modulates liver and colonic ODC and TPK activities that have been shown to play a role in tumor promotion, according to "Effect of oltipraz [5-(2-pyrazinyl)-4-methyl-1,2-dithiol-3-thione] on azoxymethane-induced biochemical changes related to early colon carcinogenesis in male F344 rats" by Rao CV, Nayini J, Reddy BS.(9)
10. Lipid peroxidation
in the observation of the drug anisyldithiolthione (ADT) acted as a good inhibitor of lipid peroxidation induced in rat liver microsomes either chemically by FeSO4 and reducing agents (cysteine or ascorbate) or enzymatically by NADPH and CC14, showed that at doses as low as 5 mg per kg it completely suppressed ethane exhalation by acetaminophen-intoxicated mice and also protected them very efficiently against mortality caused by acetaminophen overdose. The inhibitory effect of ADT toward lipid peroxidation seems to be linked to the presence of itsdithiolthione function, according to "A new potent inhibitor of lipid peroxidation in vitro and in vivo, the hepatoprotective drug anisyldithiolthione" by Mansuy D, Sassi A, Dansette PM, Plat M.(10)
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to OfferSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/2780509
(2) http://carcin.oxfordjournals.org/content/27/8/1721.abstract
(3) http://www.ncbi.nlm.nih.gov/pubmed/3744194
(4) http://www.ncbi.nlm.nih.gov/pubmed/11213483
(5) http://www.ncbi.nlm.nih.gov/pubmed/10682385
(6) http://www.ncbi.nlm.nih.gov/pubmed/9679568
(7) http://www.ncbi.nlm.nih.gov/pubmed/8685901
(8) http://www.ncbi.nlm.nih.gov/pubmed/1497692
(9) http://www.ncbi.nlm.nih.gov/pubmed/2020672
(10) http://www.ncbi.nlm.nih.gov/pubmed/3964266
Food Therapy: Lima beans (Phaseolus)
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Lima bean has a very good source of cholesterol-lowering fiber, as are most other legumes native to South America and is belong to the genus Phaseolus and the family Fabaceae. It is wigely grown for its seed, which is eaten as a vegetable.
Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Lima bean has a very good source of cholesterol-lowering fiber, as are most other legumes native to South America and is belong to the genus Phaseolus and the family Fabaceae. It is wigely grown for its seed, which is eaten as a vegetable.
Nutrients
1. Molybdenum
2. Tryptophan
3. Dietary Fiber
4. Protein
5. Manganese
6. Folate
7. Potassium
8. Iron
9. Copper
10. Phosphorus
11. Magnesium
12. Vitamin B1 (Thiamin)
13. Etc.
Health benefits
A. Health benefits according to studies
1. Antimicrobial effect
In the investigation of lunatusin, with a molecular mass around 7kDa, isolated from the seeds of Chinese lima bean (Phaseolus lunatus L.) and its antimicrobial effect found that MCF-7. Lunatusin reduced the activity of HIV-1 reverse transcriptase and it also inhibited translation in a cell-free rabbit reticulocyte lysate system. Its anti-fungal activity was retained after incubation with trypsin. Lunatusin elicited a mitogenic response from mouse splenocytes, according to "Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)" by Wong JH, Ng TB.(a)
2. Health benefits
In the examination of Six to ten local legumes were studied as follows: cowpeas, mung beans, pole sitao, chickpeas, green peas, groundnuts, pigeon peas, kidneybeans, lima beans and soyabeans and their potential health benefits found that mineral availability from legumes differs and may be attributed to their mineral content, mineral-mineral interaction and from their phytic and tannic acid content; legumes are considered low-GI foods and have shown potential hypocholesterolaemic effects. The above studies can be a scientific basis for considering legumes as functional foods, according to "The potential health benefits of legumes as a good source of dietary fibre" by Trinidad TP, Mallillin AC, Loyola AS, Sagum RS, Encabo RR.(b)
3. Estrogenic effects
In the assessment of estrogen-like activities of ethanol extracts from two common Chinese legumes, i.e. Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) were investigated found that novel pattern of (estrogen receptor)ER intracellular distribution in the MCF-7/BOS cell line upon exposure to Adzuki bean extract, suggesting that different pathways were involved in the estrogen-like activities of the ethanol extracts of Adzuki bean and Lima bean, according to "Effects of ethanol extracts from Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) on estrogen and progesterone receptor phenotypes of MCF-7/BOS cells" by Zhao QW, Huang X, Lou YJ, Weber N, Proksch P.(c)
4. Antifungal activity
In the analyzing Fusarium oxysporum, Mycosphaerella arachidicola, and Physalospora piricola isolated from baby lima beans and their antifungal activity found that the isolation exhibited an N-terminal amino acid sequence similar to those of leguminous defensins. The isolation procedure comprised ion exchange chromatography on diethylaminoethyl (DEAE)-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on carboxymethyl (CM)-cellulose, and gel filtration by fast protein liquid chromatography on Superdex 75, according to "An antifungal peptide from baby lima bean" by Wang HX, Ng TB.(d)
5. Etc.
B. Health benefits according to concentration
1. Molybdenum
Molybdenum beside plays an important role in kidneys waste processing (according to the article "Molybdenum" posted in American cancer Society), it also acts as a cofactor in carbohydrate metabolism and detoxification (according to the article of "Molybdenum Aids Fat and Carbohydrate Metabolism", posted in Nutra Legacy)
2. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(1)
3. Dietary Fibers
Daily intake of right amount of fibers can prevent and treat Diabetes. As Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(2)
4. Manganese
Manganese not only ensures the healthy bone structure, bone metabolism (according to the study of "Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants" by Pabbruwe MB, Standard OC, Sorrell CC,Howlett CR., posted in PubMed, (http://www.ncbi.nlm.nih.gov/pubmed/15109850)), it also is an very powerful antioxidant that helps to enhance the immune system in fight against the forming of free radical, thus reducing the risk of inflammation and infection and sperm cause of infertility, In a study of "Manganese provides antioxidant protection for sperm cryopreservation that may offer new consideration for clinical fertility" by Cheema RS, Bansal AK, Bilaspuri GS., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20592770), researchers found that The addition of manganese to EYC-G dilutor will improve the quality/fertility of semen, which will result in improvement of in vitro fertilization and artificial insemination success rate.
5. Etc.
C. Other health benefits
1. Vitamin B1
Vitamin B1 or thiamine beside promotesthe function of other B vitamins, it also helps in the production of the neurotransmitter, acetylcholine which is important for relay messages of nerves and muscles.
2. Tryptophan
Beside having the effect of above, it also help in enhancing mood, and regulating appetite and melatonin production and reducing the craving for carbohydrate, leading to weight loss for some people, according to the article of "L-TryptophanNeurological Support" by Douglas Laboratory,the author wrote that Serotonin, an important brain neurotransmitter,is key in the regulation of appetite, mood, andmelatonin production. Serotonin is unable to cross the blood-brainbarrier and is therefore synthesized in the brain.Tryptophan, an essential amino acid, is aprecursor for the synthesis of serotonin.Tryptophan crosses the blood-brain barrier andis converted to L-5-Hydroxytryptophan (5-HTP),which in turn is converted into serotonin.
3. Phosphorus
Phosphorous not only is one of the important trace minerals in bone formation, according to the study of "What is next for the Dietary Reference Intakes for bone metabolism related nutrients beyond calcium: phosphorus, magnesium, vitamin D, and fluoride?" by Bergman C, Gray-Scott D, Chen JJ, Meacham S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18989832), it also plays a vital role in maintaining the proper brain functions, thus enhancing the brain cells in information transmitting that reduce the risk of nervous tension, acording to the article of "Health Benefits of Phosphorus". posted in Organic Facts
4. Potassium
Potassium beside is important in helping the sympathic system in regulating the fuild in the body, it also is important in transmitting the electrical conductivity of brain properly in regulating neuronal excitability and behavior.s,, according to the study of "In vivo role of a potassium channel-binding protein in regulating neuronal excitability and behavior" by Shahidullah M, Reddy S, Fei H, Levitan IB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19846720).
5. Etc.
Side effects
1. Since it contains a measurable amount of purines which can break down to uric acid that cause problem for people with with kidney and gallbladder diseases.
2. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/16269344
(b) http://www.ncbi.nlm.nih.gov/pubmed/19825218
(c) http://www.ncbi.nlm.nih.gov/pubmed/17397133
(d) http://www.ncbi.nlm.nih.gov/pubmed/16850300
(1) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(2) http://www.ncbi.nlm.nih.gov/pubmed/20713332
2. Tryptophan
3. Dietary Fiber
4. Protein
5. Manganese
6. Folate
7. Potassium
8. Iron
9. Copper
10. Phosphorus
11. Magnesium
12. Vitamin B1 (Thiamin)
13. Etc.
Health benefits
A. Health benefits according to studies
1. Antimicrobial effect
In the investigation of lunatusin, with a molecular mass around 7kDa, isolated from the seeds of Chinese lima bean (Phaseolus lunatus L.) and its antimicrobial effect found that MCF-7. Lunatusin reduced the activity of HIV-1 reverse transcriptase and it also inhibited translation in a cell-free rabbit reticulocyte lysate system. Its anti-fungal activity was retained after incubation with trypsin. Lunatusin elicited a mitogenic response from mouse splenocytes, according to "Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)" by Wong JH, Ng TB.(a)
2. Health benefits
In the examination of Six to ten local legumes were studied as follows: cowpeas, mung beans, pole sitao, chickpeas, green peas, groundnuts, pigeon peas, kidneybeans, lima beans and soyabeans and their potential health benefits found that mineral availability from legumes differs and may be attributed to their mineral content, mineral-mineral interaction and from their phytic and tannic acid content; legumes are considered low-GI foods and have shown potential hypocholesterolaemic effects. The above studies can be a scientific basis for considering legumes as functional foods, according to "The potential health benefits of legumes as a good source of dietary fibre" by Trinidad TP, Mallillin AC, Loyola AS, Sagum RS, Encabo RR.(b)
3. Estrogenic effects
In the assessment of estrogen-like activities of ethanol extracts from two common Chinese legumes, i.e. Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) were investigated found that novel pattern of (estrogen receptor)ER intracellular distribution in the MCF-7/BOS cell line upon exposure to Adzuki bean extract, suggesting that different pathways were involved in the estrogen-like activities of the ethanol extracts of Adzuki bean and Lima bean, according to "Effects of ethanol extracts from Adzuki bean (Phaseolus angularis Wight.) and Lima bean (Phaseolus lunatus L.) on estrogen and progesterone receptor phenotypes of MCF-7/BOS cells" by Zhao QW, Huang X, Lou YJ, Weber N, Proksch P.(c)
4. Antifungal activity
In the analyzing Fusarium oxysporum, Mycosphaerella arachidicola, and Physalospora piricola isolated from baby lima beans and their antifungal activity found that the isolation exhibited an N-terminal amino acid sequence similar to those of leguminous defensins. The isolation procedure comprised ion exchange chromatography on diethylaminoethyl (DEAE)-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on carboxymethyl (CM)-cellulose, and gel filtration by fast protein liquid chromatography on Superdex 75, according to "An antifungal peptide from baby lima bean" by Wang HX, Ng TB.(d)
5. Etc.
B. Health benefits according to concentration
1. Molybdenum
Molybdenum beside plays an important role in kidneys waste processing (according to the article "Molybdenum" posted in American cancer Society), it also acts as a cofactor in carbohydrate metabolism and detoxification (according to the article of "Molybdenum Aids Fat and Carbohydrate Metabolism", posted in Nutra Legacy)
2. Tryptophan
Tryptophan is one of the 10 essential amino acids which the body uses to synthesize the proteins for brain cells need, thus enhancing the nerve cells in information transmitting between themselves and cells in the parts of the body that reduces the risk of anxiety and depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(1)
3. Dietary Fibers
Daily intake of right amount of fibers can prevent and treat Diabetes. As Increased consumption of vegetables, whole grains, and soluble and insoluble fiber is associated with improved glucose metabolism in both diabetic and nondiabetic individuals. Improvements in insulin sensitivity and glucose homeostasis were more evident in participants following a plant-based diet compared with other commonly used diets, according to the study of "Efficacy of high-fiber diets in the management of type 2 diabetes mellitus" by Wolfram T, Ismail-Beigi F.(2)
4. Manganese
Manganese not only ensures the healthy bone structure, bone metabolism (according to the study of "Bone formation within alumina tubes: effect of calcium, manganese, and chromium dopants" by Pabbruwe MB, Standard OC, Sorrell CC,Howlett CR., posted in PubMed, (http://www.ncbi.nlm.nih.gov/pubmed/15109850)), it also is an very powerful antioxidant that helps to enhance the immune system in fight against the forming of free radical, thus reducing the risk of inflammation and infection and sperm cause of infertility, In a study of "Manganese provides antioxidant protection for sperm cryopreservation that may offer new consideration for clinical fertility" by Cheema RS, Bansal AK, Bilaspuri GS., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/20592770), researchers found that The addition of manganese to EYC-G dilutor will improve the quality/fertility of semen, which will result in improvement of in vitro fertilization and artificial insemination success rate.
5. Etc.
C. Other health benefits
1. Vitamin B1
Vitamin B1 or thiamine beside promotesthe function of other B vitamins, it also helps in the production of the neurotransmitter, acetylcholine which is important for relay messages of nerves and muscles.
2. Tryptophan
Beside having the effect of above, it also help in enhancing mood, and regulating appetite and melatonin production and reducing the craving for carbohydrate, leading to weight loss for some people, according to the article of "L-TryptophanNeurological Support" by Douglas Laboratory,the author wrote that Serotonin, an important brain neurotransmitter,is key in the regulation of appetite, mood, andmelatonin production. Serotonin is unable to cross the blood-brainbarrier and is therefore synthesized in the brain.Tryptophan, an essential amino acid, is aprecursor for the synthesis of serotonin.Tryptophan crosses the blood-brain barrier andis converted to L-5-Hydroxytryptophan (5-HTP),which in turn is converted into serotonin.
3. Phosphorus
Phosphorous not only is one of the important trace minerals in bone formation, according to the study of "What is next for the Dietary Reference Intakes for bone metabolism related nutrients beyond calcium: phosphorus, magnesium, vitamin D, and fluoride?" by Bergman C, Gray-Scott D, Chen JJ, Meacham S., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/18989832), it also plays a vital role in maintaining the proper brain functions, thus enhancing the brain cells in information transmitting that reduce the risk of nervous tension, acording to the article of "Health Benefits of Phosphorus". posted in Organic Facts
4. Potassium
Potassium beside is important in helping the sympathic system in regulating the fuild in the body, it also is important in transmitting the electrical conductivity of brain properly in regulating neuronal excitability and behavior.s,, according to the study of "In vivo role of a potassium channel-binding protein in regulating neuronal excitability and behavior" by Shahidullah M, Reddy S, Fei H, Levitan IB., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/19846720).
5. Etc.
Side effects
1. Since it contains a measurable amount of purines which can break down to uric acid that cause problem for people with with kidney and gallbladder diseases.
2. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(a) http://www.ncbi.nlm.nih.gov/pubmed/16269344
(b) http://www.ncbi.nlm.nih.gov/pubmed/19825218
(c) http://www.ncbi.nlm.nih.gov/pubmed/17397133
(d) http://www.ncbi.nlm.nih.gov/pubmed/16850300
(1) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(2) http://www.ncbi.nlm.nih.gov/pubmed/20713332
Traditional Chinese Medicine Herbal Therapy - Popular Herbal Ai Ye (Folium artemisiae argyi)
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Ai Ye is also known as Mugwort leaf, a species of A. Vulgaris, belonging to the family Asteraceae, native to native to temperate Europe, Asia, northern Africa and Alaska and is naturalized in North America. The bitter, acrid and warm herb has been used in TCM as antibiotic and anti virus and to relax the smooth muscles of bronchi and stop bleeding as it helps to relieve pain, warm the channels and disperses cold by promoting the functions of spleen, liver, kidney channels.
Ingredients
A. Volatile oils
1. Alpha -phellandrene
2. Camphenbe
3. Alpha-cedrene
4. Transcarveol
5. Bornyl acetate
6. Elemol, isoborneol
7. Alpha-terpineol
8. Beta-caryophyllene
9. Carvone
10. Cadinene
11. Etc.
B. Triterpenes
1. Alpha-amyrin
2. Beta-amyrin,
3. Friedelin, 9beta,
4. Methoxy-9beta
5. Etc.
C. Terpenes
1. Matricarin
2. Hanphyllin
3. 13-dihydroalteglasin
4. Etc.
D. Others
1. Flavone alcohol
2. Eupatilin,
3. Beta-sitostero
4. Silicon
5. Etc.
Health benefits
1. Beta-sitostero
Beta-sitostero enhances the ratio of HDL in blood levels of cholesterol, and is used in treating hypercholesterolemia by inhibiting cholesterol absorption in the intestine. Over-doses can cause premature coronary artery disease and tendon xanthoma.
2. Desacetoxymatricarin
Cytotoxic and antitumour activities in Ai ye may have anticarcinogenic potential by exhibiting a significantly higher antiproliferative action on cancer cell lines in some researches.
3. Anti-inflammatory properties
Ai ye contains certain compounds such as beta-caryophyllene by ehnacing the immune system in protecting the body against bacterial and virus intruders and irregular cells cause of inflammation.
4. Skin protector
Ai Ye beside acts a precursor of ursolic acid, alpha-amyrin contains a property of anti elastase activity by preventing UV-B irradiation damages to the skin through prevention of lipid peroxidation and PGE2 release inhibition, but also protect the skin inflammation disorder by inhibiting activity against 5-LOX-catalyzed leukotriene production and delayed-type hypersensitivity response in mice, according to the study of “Inhibition of 5-lipoxygenase and skin inflammation by the aerial parts of Artemisia capillaris and its constituents” by Kwon OS, Choi JS, Islam MN, Kim YS, Kim HP., posted in PubMed(1).
5. Anesthetic and Analgesic properties
Beta-caryophyllenein found in Ai ye can react in various ways on the peripheral and central nervous systems in relieving pain and used as anesthesia in relieving pain during local surgery.
6. Anti parasite Trichinosis
Trichinosis is a parasitc disease eating raw or undercooked pork or wild game infected with the larvae of a species of roundworm, causing disgestive disorder, including diarrhea, etc., periorbital edema and myositis. Extract of the aerial parts of A. vulgaris and A. absinthium have exhibited the function of the herbs in reducing the presentence of larva significantly, according to the study of “Comparison of the effects of Artemisia vulgaris and Artemisia absinthium growing in western Anatolia against trichinellosis (Trichinella spiralis) in rats” by Caner A, Döşkaya M, Değirmenci A, Can H, Baykan S, Uner A, Başdemir G, Zeybek U, Gürüz Y., posted in PubMed(2).
7. Gut and airways disorders
Antioxiadants, including alkaloids, coumarins, flavonoids, saponins, sterols, etc. from the extract of extract of Artemisia vulgaris (Av.Cr) have shown a property of exhibited protective effect against castor oil-induced diarrhea and CCh-mediated bronchoconstriction in rodents, according to the study of “Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx” by Khan AU, Gilani AH., posted in PubMed(3).
8. Antioxidants
extract of the plant have shown activity of inhibition of inhibited cerebral I/R-induced oxidative stress by decreasing TBARS, and restoring levels of SOD and GSH and may be used as a protective agent against disorders associated with oxidative stress, according to the study of “Evaluation of antioxidant and free-radical scavenging potential of Artemisia absinthium” by Bora KS, Sharma A., posted in PubMed(4)
9. Cancer
Methanol, ethyl acetate, dichloromethane and n-hexane extracts from aerial parts of seven species of Artemisia have exhibited the activity in antiantiproliferation of the growth of caner cells, according tothe study of “Antiproliferative effects of extracts from Iranian Artemisia species on cancer cell lines” by Taghizadeh Rabe SZ, Mahmoudi M, Ahi A, Emami SA., posted in PubMed(5)
10. Etc.
Side effects
Overdose
1. It can cause inflammation of the skin mucus.
2. Orally, it can cause irritation of the of the digestive tract
3. Allergic effect
Thionin-like protein with a bulky arabinogalactan-protein moiety, a pollen allergen of the composite plant mugwort can cause alergic effect to certain people affected by rawweed pollen, according to the study of “A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort” by Léonard R, Wopfner N, Pabst M, Stadlmann J, Petersen BO, Duus JØ, Himly M, Radauer C, Gadermaier G, Razzazi-Fazeli E, Ferreira F, Altmann F., posted in PubMed(a)
4. It can damage the walls of blood vessels and cause hyperemia
5. Nervous tension
6. Do not the medicine, if you are pregnant.
7. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21975819
(2) http://www.ncbi.nlm.nih.gov/pubmed/18325496
(3) http://www.ncbi.nlm.nih.gov/pubmed/19751814
(4) http://www.ncbi.nlm.nih.gov/pubmed/21999109
(5) http://www.ncbi.nlm.nih.gov/pubmed/21592012
(a) http://www.ncbi.nlm.nih.gov/pubmed/20576600
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Ai Ye is also known as Mugwort leaf, a species of A. Vulgaris, belonging to the family Asteraceae, native to native to temperate Europe, Asia, northern Africa and Alaska and is naturalized in North America. The bitter, acrid and warm herb has been used in TCM as antibiotic and anti virus and to relax the smooth muscles of bronchi and stop bleeding as it helps to relieve pain, warm the channels and disperses cold by promoting the functions of spleen, liver, kidney channels.
Ingredients
A. Volatile oils
1. Alpha -phellandrene
2. Camphenbe
3. Alpha-cedrene
4. Transcarveol
5. Bornyl acetate
6. Elemol, isoborneol
7. Alpha-terpineol
8. Beta-caryophyllene
9. Carvone
10. Cadinene
11. Etc.
B. Triterpenes
1. Alpha-amyrin
2. Beta-amyrin,
3. Friedelin, 9beta,
4. Methoxy-9beta
5. Etc.
C. Terpenes
1. Matricarin
2. Hanphyllin
3. 13-dihydroalteglasin
4. Etc.
D. Others
1. Flavone alcohol
2. Eupatilin,
3. Beta-sitostero
4. Silicon
5. Etc.
Health benefits
1. Beta-sitostero
Beta-sitostero enhances the ratio of HDL in blood levels of cholesterol, and is used in treating hypercholesterolemia by inhibiting cholesterol absorption in the intestine. Over-doses can cause premature coronary artery disease and tendon xanthoma.
2. Desacetoxymatricarin
Cytotoxic and antitumour activities in Ai ye may have anticarcinogenic potential by exhibiting a significantly higher antiproliferative action on cancer cell lines in some researches.
3. Anti-inflammatory properties
Ai ye contains certain compounds such as beta-caryophyllene by ehnacing the immune system in protecting the body against bacterial and virus intruders and irregular cells cause of inflammation.
4. Skin protector
Ai Ye beside acts a precursor of ursolic acid, alpha-amyrin contains a property of anti elastase activity by preventing UV-B irradiation damages to the skin through prevention of lipid peroxidation and PGE2 release inhibition, but also protect the skin inflammation disorder by inhibiting activity against 5-LOX-catalyzed leukotriene production and delayed-type hypersensitivity response in mice, according to the study of “Inhibition of 5-lipoxygenase and skin inflammation by the aerial parts of Artemisia capillaris and its constituents” by Kwon OS, Choi JS, Islam MN, Kim YS, Kim HP., posted in PubMed(1).
5. Anesthetic and Analgesic properties
Beta-caryophyllenein found in Ai ye can react in various ways on the peripheral and central nervous systems in relieving pain and used as anesthesia in relieving pain during local surgery.
6. Anti parasite Trichinosis
Trichinosis is a parasitc disease eating raw or undercooked pork or wild game infected with the larvae of a species of roundworm, causing disgestive disorder, including diarrhea, etc., periorbital edema and myositis. Extract of the aerial parts of A. vulgaris and A. absinthium have exhibited the function of the herbs in reducing the presentence of larva significantly, according to the study of “Comparison of the effects of Artemisia vulgaris and Artemisia absinthium growing in western Anatolia against trichinellosis (Trichinella spiralis) in rats” by Caner A, Döşkaya M, Değirmenci A, Can H, Baykan S, Uner A, Başdemir G, Zeybek U, Gürüz Y., posted in PubMed(2).
7. Gut and airways disorders
Antioxiadants, including alkaloids, coumarins, flavonoids, saponins, sterols, etc. from the extract of extract of Artemisia vulgaris (Av.Cr) have shown a property of exhibited protective effect against castor oil-induced diarrhea and CCh-mediated bronchoconstriction in rodents, according to the study of “Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx” by Khan AU, Gilani AH., posted in PubMed(3).
8. Antioxidants
extract of the plant have shown activity of inhibition of inhibited cerebral I/R-induced oxidative stress by decreasing TBARS, and restoring levels of SOD and GSH and may be used as a protective agent against disorders associated with oxidative stress, according to the study of “Evaluation of antioxidant and free-radical scavenging potential of Artemisia absinthium” by Bora KS, Sharma A., posted in PubMed(4)
9. Cancer
Methanol, ethyl acetate, dichloromethane and n-hexane extracts from aerial parts of seven species of Artemisia have exhibited the activity in antiantiproliferation of the growth of caner cells, according tothe study of “Antiproliferative effects of extracts from Iranian Artemisia species on cancer cell lines” by Taghizadeh Rabe SZ, Mahmoudi M, Ahi A, Emami SA., posted in PubMed(5)
10. Etc.
Side effects
Overdose
1. It can cause inflammation of the skin mucus.
2. Orally, it can cause irritation of the of the digestive tract
3. Allergic effect
Thionin-like protein with a bulky arabinogalactan-protein moiety, a pollen allergen of the composite plant mugwort can cause alergic effect to certain people affected by rawweed pollen, according to the study of “A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort” by Léonard R, Wopfner N, Pabst M, Stadlmann J, Petersen BO, Duus JØ, Himly M, Radauer C, Gadermaier G, Razzazi-Fazeli E, Ferreira F, Altmann F., posted in PubMed(a)
4. It can damage the walls of blood vessels and cause hyperemia
5. Nervous tension
6. Do not the medicine, if you are pregnant.
7. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21975819
(2) http://www.ncbi.nlm.nih.gov/pubmed/18325496
(3) http://www.ncbi.nlm.nih.gov/pubmed/19751814
(4) http://www.ncbi.nlm.nih.gov/pubmed/21999109
(5) http://www.ncbi.nlm.nih.gov/pubmed/21592012
(a) http://www.ncbi.nlm.nih.gov/pubmed/20576600
Herbal therapy: Popular Herbal Cinnamon
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae.. The herb has been use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.
Health Benefits
1. Diabetes
In the investigation of the clinical potential of aqueous extract of cinnamon and it potential effects in diabetes found that high in type A polyphenols, have also demonstrated improvements in fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome, according to"Chromium and polyphenols from cinnamon improve insulin sensitivity" by Anderson RA.(1)
2. Immunomodulatory effect
In administration of popular herb used in traditional medicine to treat various disorders such as chronic gastric symptoms, arthritis, and the common cold and its immunomodulatory effect found that observations provided evidence that CWE was able to down-regulate IFN-γ expression in activated T cells without altering IL-2 production, involving inhibition of p38, JNK, ERK1/2, and STAT4, according to the study of "Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation" by Lee BJ, Kim YJ, Cho DH, Sohn NW, Kang H.(2)
3. Antimicrobial Activities
In the observation of three natural essential oils (i.e., clove bud oil, cinnamon oil, and star anise oil) and their antimicrobal effects found that the cinnamon oil-chitosan film had also better antimicrobial activity than the clove bud oil-chitosan film. The results also showed that the compatibility of cinnamon oil with chitosan in film formation was better than that of the clove bud oil with chitosan, according to the study of "Synergistic Antimicrobial Activities of Natural Essential Oils with Chitosan Films" by Wang L, Liu F, Jiang Y, Chai Z, Li P, Cheng Y, Jing H, Leng X.(3)
4. Anti-inflammatory activity
In the investigation of Myristicin (1-allyl-5-methoxy-3,4-methylenedioxybenzene) is an active aromatic compound found in nutmeg (the seed of Myristica fragrans), carrot, basil,cinnamon, and parsley and it anti-inflammatory effects found that Myristicin significantly inhibited the production of calcium, nitric oxide (NO),interleukin (IL)-6, IL-10, interferon inducible protein-10, monocyte chemotactic protein(MCP)-1, MCP-3, granulocyte-macrophage colony-stimulating factor, macrophage inflammatory protein (MIP)-1α, MIP-1β, and leukemia inhibitory factor in dsRNA[polyinosinic-polycytidylic acid]-induced RAW 264.7 cells (P < 0.05), according to the study of "Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid" by Lee JY, Park W.(4)
5. Cervical Cancer
In the evaluation of Eugenol, a potential chemopreventive agent, is a component of clove and several other spices such as basil, cinnamon, and bay leaves and its anti cancer effects found that eugenol exerts its anticancer activities via apoptosis induction and anti-inflammatory properties and also provide the first evidence demonstrating synergism between eugenol and gemcitabine, which may enhance the therapeutic index of prevention and/or treatment of cervical cancer, according to the study of "Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells" by Hussain A, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(5)
6. Menstrual pain
In the investigation of the alleviating effects of aromatherapy massage, including clary sage, marjoram, cinnamon, ginger, and geranium in a base of almond oil and acetaminophen on menstrual pain in Korean high school girls found that aromatherapy massage was found to be more highly associated with reduction in the level of menstrual pain than acetaminophen, according to the study of "Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study" by Hur MH, Lee MS, Seong KY, Lee MK.(6)
7. Systolic Blood Pressure
In this study adult subjects 30 years of age or older with type 2 diabetes were randomized to treatment with 1,200 mg/day cinnamon found that Systolic blood pressure (SBP) declined from baseline values by 3.4±11.4 mm Hg in the cinnamongroup, according to the study of "Dietary Cinnamon Supplementation and Changes in Systolic Blood Pressure in Subjects with Type 2 Diabetes" by Wainstein J, Stern N, Heller S, Boaz M.(7)
8. Anti biotic
In the investigation of cinnamaldehyde its effects in Campylobacter jejuni which is the leading cause of bacterial diarrheal illness worldwide found that Films with ≥1.5% cinnamaldehyde reduced populations of all strains to below detection at 23 °C at 72 h. At 4 °C with cinnamaldehyde, reductions were variable for all strains, ranging from 0.2 to 2.5 logs and 1.8 to 6.0 logs at 1.5% and 3.0%, according to the study of "Antimicrobial edible apple films inactivate antibiotic resistant and susceptible Campylobacter jejuni strains on chicken breast" by Mild RM, Joens LA, Friedman M, Olsen CW, McHugh TH, Law B, Ravishankar S.(8)
9. Anti-atherosclerotic activity
In the observation of Aqueous extracts of ground pepper, cinnamon, rosemary, ginger, and clove and their effects in pathogenesis of diabetic complications and atherosclerosis found that Hydrophilic ingredients of cinnamon and clove showed potent activities to suppress the incidence of atherosclerosis and diabetes via strong antioxidant potential, prevention of apoA-I glycation and LDL-phagocytosis, following a 5-week high cholesterol diet, according to the study of "Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish" by Jin S, Cho KH.(9)
10. Antihyperglycemic and antihyperlipidemic effects
In the investigation of of Cinnamomi Cassiae extract of Cinnamon and it effects in antihyperglycemic and antihyperlipidemic found that the fasting blood glucose and postprandial 2 h blood glucose levels in the cinnamon treated group were significantly lower than those in the control group (p < 0.01), whereas the serum insulin and adiponectin levels were significantly higher in the cinnamon treated group than in the control group (p < 0.05). The serum lipids and hepatic lipids were improved in the cinnamon administered group. Also the PPARalpha mRNA (liver) and PPARgamma mRNA (adipose tissue) expression levels were increased significantly in the cinnamon treated group (p < 0.05) in test mices, according to the study of "Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice" by Kim SH, Choung SY.(10)
11. Osteopenic disease
In the evaluation of Cinnamon zeylanicum and its effects in bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis found that cinnamaldehyde and 2-methoxycinnamaldehyde as active components reducing osteoclast-like cell formation and inhibiting NFATc1 expression. Notably, in a resorption pit assay, 2-methoxycinnamaldehyde exhibited remarkable inhibition rates of 95% at 2 microM on bone resorption and concluded that Cinnamon zeylanicum inhibits RANKL-induced osteoclastogenesis. This finding raises prospects for the development of a novel approach in the treatment of osteopenic disease, according to the study of "Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation" by Tsuji-Naito K.(11)
12. Cognitive impairment
In the examination of Orally administrated cinnamon extract and it effects in cognitive impairment found that oral administration of CEppt to an aggressive AD transgenic mice model led to marked decrease in 56 kDa Aβ oligomers, reduction of plaques and improvement in cognitive behavior, according to the study of"Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal model" byFrydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M.(12)
13. Etc.
Side effects
1. Oral intake of Cinnamon may cause Stomatitis, according to the study of "Cinnamon contact stomatitis" by Georgakopoulou EA.(a)
2. Consult with your doctor if you are taking anticoagulation medicine before applying.
3. Do not use Cinnamon if you are pregnant without consulting with related field specialist.
4. Overdoses can be toxic and damaged to liver.
5. Do not use the herb in children.
6. Oral intake may cause burning sensation in mouth with large amount
7. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/18234131
(2) http://www.ncbi.nlm.nih.gov/pubmed/22053946
(3) http://www.ncbi.nlm.nih.gov/pubmed/22034912
(4) http://www.ncbi.nlm.nih.gov/pubmed/21991618
(5) http://www.ncbi.nlm.nih.gov/pubmed/21939359
(6) http://www.ncbi.nlm.nih.gov/pubmed/21949670
(7) http://www.ncbi.nlm.nih.gov/pubmed/21861719
(8) http://www.ncbi.nlm.nih.gov/pubmed/21535839
(9) http://www.ncbi.nlm.nih.gov/pubmed/21443916
(10) http://www.ncbi.nlm.nih.gov/pubmed/20195835
(11) http://www.ncbi.nlm.nih.gov/pubmed/18823786
(12) http://www.ncbi.nlm.nih.gov/pubmed/21305046
(a) http://www.ncbi.nlm.nih.gov/pubmed/21886744
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae.. The herb has been use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.
Health Benefits
1. Diabetes
In the investigation of the clinical potential of aqueous extract of cinnamon and it potential effects in diabetes found that high in type A polyphenols, have also demonstrated improvements in fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome, according to"Chromium and polyphenols from cinnamon improve insulin sensitivity" by Anderson RA.(1)
2. Immunomodulatory effect
In administration of popular herb used in traditional medicine to treat various disorders such as chronic gastric symptoms, arthritis, and the common cold and its immunomodulatory effect found that observations provided evidence that CWE was able to down-regulate IFN-γ expression in activated T cells without altering IL-2 production, involving inhibition of p38, JNK, ERK1/2, and STAT4, according to the study of "Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation" by Lee BJ, Kim YJ, Cho DH, Sohn NW, Kang H.(2)
3. Antimicrobial Activities
In the observation of three natural essential oils (i.e., clove bud oil, cinnamon oil, and star anise oil) and their antimicrobal effects found that the cinnamon oil-chitosan film had also better antimicrobial activity than the clove bud oil-chitosan film. The results also showed that the compatibility of cinnamon oil with chitosan in film formation was better than that of the clove bud oil with chitosan, according to the study of "Synergistic Antimicrobial Activities of Natural Essential Oils with Chitosan Films" by Wang L, Liu F, Jiang Y, Chai Z, Li P, Cheng Y, Jing H, Leng X.(3)
4. Anti-inflammatory activity
In the investigation of Myristicin (1-allyl-5-methoxy-3,4-methylenedioxybenzene) is an active aromatic compound found in nutmeg (the seed of Myristica fragrans), carrot, basil,cinnamon, and parsley and it anti-inflammatory effects found that Myristicin significantly inhibited the production of calcium, nitric oxide (NO),interleukin (IL)-6, IL-10, interferon inducible protein-10, monocyte chemotactic protein(MCP)-1, MCP-3, granulocyte-macrophage colony-stimulating factor, macrophage inflammatory protein (MIP)-1α, MIP-1β, and leukemia inhibitory factor in dsRNA[polyinosinic-polycytidylic acid]-induced RAW 264.7 cells (P < 0.05), according to the study of "Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid" by Lee JY, Park W.(4)
5. Cervical Cancer
In the evaluation of Eugenol, a potential chemopreventive agent, is a component of clove and several other spices such as basil, cinnamon, and bay leaves and its anti cancer effects found that eugenol exerts its anticancer activities via apoptosis induction and anti-inflammatory properties and also provide the first evidence demonstrating synergism between eugenol and gemcitabine, which may enhance the therapeutic index of prevention and/or treatment of cervical cancer, according to the study of "Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells" by Hussain A, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(5)
6. Menstrual pain
In the investigation of the alleviating effects of aromatherapy massage, including clary sage, marjoram, cinnamon, ginger, and geranium in a base of almond oil and acetaminophen on menstrual pain in Korean high school girls found that aromatherapy massage was found to be more highly associated with reduction in the level of menstrual pain than acetaminophen, according to the study of "Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study" by Hur MH, Lee MS, Seong KY, Lee MK.(6)
7. Systolic Blood Pressure
In this study adult subjects 30 years of age or older with type 2 diabetes were randomized to treatment with 1,200 mg/day cinnamon found that Systolic blood pressure (SBP) declined from baseline values by 3.4±11.4 mm Hg in the cinnamongroup, according to the study of "Dietary Cinnamon Supplementation and Changes in Systolic Blood Pressure in Subjects with Type 2 Diabetes" by Wainstein J, Stern N, Heller S, Boaz M.(7)
8. Anti biotic
In the investigation of cinnamaldehyde its effects in Campylobacter jejuni which is the leading cause of bacterial diarrheal illness worldwide found that Films with ≥1.5% cinnamaldehyde reduced populations of all strains to below detection at 23 °C at 72 h. At 4 °C with cinnamaldehyde, reductions were variable for all strains, ranging from 0.2 to 2.5 logs and 1.8 to 6.0 logs at 1.5% and 3.0%, according to the study of "Antimicrobial edible apple films inactivate antibiotic resistant and susceptible Campylobacter jejuni strains on chicken breast" by Mild RM, Joens LA, Friedman M, Olsen CW, McHugh TH, Law B, Ravishankar S.(8)
9. Anti-atherosclerotic activity
In the observation of Aqueous extracts of ground pepper, cinnamon, rosemary, ginger, and clove and their effects in pathogenesis of diabetic complications and atherosclerosis found that Hydrophilic ingredients of cinnamon and clove showed potent activities to suppress the incidence of atherosclerosis and diabetes via strong antioxidant potential, prevention of apoA-I glycation and LDL-phagocytosis, following a 5-week high cholesterol diet, according to the study of "Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish" by Jin S, Cho KH.(9)
10. Antihyperglycemic and antihyperlipidemic effects
In the investigation of of Cinnamomi Cassiae extract of Cinnamon and it effects in antihyperglycemic and antihyperlipidemic found that the fasting blood glucose and postprandial 2 h blood glucose levels in the cinnamon treated group were significantly lower than those in the control group (p < 0.01), whereas the serum insulin and adiponectin levels were significantly higher in the cinnamon treated group than in the control group (p < 0.05). The serum lipids and hepatic lipids were improved in the cinnamon administered group. Also the PPARalpha mRNA (liver) and PPARgamma mRNA (adipose tissue) expression levels were increased significantly in the cinnamon treated group (p < 0.05) in test mices, according to the study of "Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice" by Kim SH, Choung SY.(10)
11. Osteopenic disease
In the evaluation of Cinnamon zeylanicum and its effects in bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis found that cinnamaldehyde and 2-methoxycinnamaldehyde as active components reducing osteoclast-like cell formation and inhibiting NFATc1 expression. Notably, in a resorption pit assay, 2-methoxycinnamaldehyde exhibited remarkable inhibition rates of 95% at 2 microM on bone resorption and concluded that Cinnamon zeylanicum inhibits RANKL-induced osteoclastogenesis. This finding raises prospects for the development of a novel approach in the treatment of osteopenic disease, according to the study of "Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation" by Tsuji-Naito K.(11)
12. Cognitive impairment
In the examination of Orally administrated cinnamon extract and it effects in cognitive impairment found that oral administration of CEppt to an aggressive AD transgenic mice model led to marked decrease in 56 kDa Aβ oligomers, reduction of plaques and improvement in cognitive behavior, according to the study of"Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal model" byFrydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M.(12)
13. Etc.
Side effects
1. Oral intake of Cinnamon may cause Stomatitis, according to the study of "Cinnamon contact stomatitis" by Georgakopoulou EA.(a)
2. Consult with your doctor if you are taking anticoagulation medicine before applying.
3. Do not use Cinnamon if you are pregnant without consulting with related field specialist.
4. Overdoses can be toxic and damaged to liver.
5. Do not use the herb in children.
6. Oral intake may cause burning sensation in mouth with large amount
7. Etc.
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/18234131
(2) http://www.ncbi.nlm.nih.gov/pubmed/22053946
(3) http://www.ncbi.nlm.nih.gov/pubmed/22034912
(4) http://www.ncbi.nlm.nih.gov/pubmed/21991618
(5) http://www.ncbi.nlm.nih.gov/pubmed/21939359
(6) http://www.ncbi.nlm.nih.gov/pubmed/21949670
(7) http://www.ncbi.nlm.nih.gov/pubmed/21861719
(8) http://www.ncbi.nlm.nih.gov/pubmed/21535839
(9) http://www.ncbi.nlm.nih.gov/pubmed/21443916
(10) http://www.ncbi.nlm.nih.gov/pubmed/20195835
(11) http://www.ncbi.nlm.nih.gov/pubmed/18823786
(12) http://www.ncbi.nlm.nih.gov/pubmed/21305046
(a) http://www.ncbi.nlm.nih.gov/pubmed/21886744
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