Wednesday, June 15, 2016

Herbal therapy: Popular Herbal Gotu Kola (Centella asiatica)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 Gotu Kola (Centella asiatica)

Gotu Kola also known as centella, is a annual plant of the genus, belonging to the family Mackinlayaceae, native to India, Sri Lanka, northern Australia, Indonesia, Iran, Malaysia, Melanesia, Papua New Guinea. The herb has been used in traditional medicine to treatnervous disorders, epilepsy, senility, premature aging, etc.

Health Benefits
1. Glycaemic index
In the testing the a significant negative correlation between the GI of Sri Lankan meals and fibre content, including Centella asiatica (gotukola) as its indicating the potential to reduce the GI of meals by incorporating naturally occurring sources of fibre found that that the GI of rice mixed meals may be reduced by including naturally occurring sources of fibre with starchy staples while fulfilling daily dietary fibre requirement of an adult at low cost, according to "Sri Lankan rice mixed meals: effect on glycaemic index and contribution to daily dietary fibre requirement" by Hettiaratchi UP, Ekanayake S, Welihinda J.(1)

2. Hyperglycemia and hypertension
In the determination of the inhibitory potential of selected Malaysian plants, including pegaga (Centella asiatica) against key enzymes related to type 2 diabetes and hypertension, found that In alpha-amylase inhibition assay, the inhibitory potential was highest in pucuk ubi for both hexane (59.22%) and dichloromethane extract (54.15%). Hexane extract of pucuk ubi (95.01%) and dichloromethane extract of kacang botol (38.94%) showed the highest inhibitory potential against alpha-glucosidase, while in ACE inhibition assay, the inhibitory potential was highest in hexane extract of pegaga (48.45%) and dichloromethane extract of pucuk betik (59.77%), according to "In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension" by Loh SP, Hadira O.(2)

3. Locomotor activity
In the investigation of the asiatic acid, a triterpenoids isolated from Centellaasiatica and its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. found that asiatic acid having an effect on AChE, a selective GABA(B) receptor agonist and no sedative effect on locomotor, according to "Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synapticpotential and locomotor activity" by Nasir MN, Abdullah J, Habsah M, Ghani RI, Rammes G.(3)

4. Premature senescence (SIPS)
In the demonstration of the effect of C. asiatica extracts on stress-induced premature senescence (SIPS) found that C. asiatica extracts rescued the H(2) O(2) -induced repression of replication in HDFs. Therefore, the findings presented here suggest that C. asiatica extracts might regulate SIPS by preventing repression of DNA replication and mitosis-related gene expression, according to "Centella asiatica extracts modulate hydrogen peroxide-induced senescence in human dermal fibroblasts" by Kim YJ, Cha HJ, Nam KH, Yoon Y, Lee H, An S.(4)

5. Cognitive effects
In the assessment of the role of "Brahmi" (Bocopa monnieri and Centella asiatica) and its effect on the loss of memory, cognitive deficits, impaired mental function found that both plants possess neuroprotective properties, have nootropic activity with therapeutic implications for patients with memory loss. The field has witnessed exciting patent activity with most inventions aiming at either (i) improving the methods of herbal extraction or (ii) enrichment and purification of novel compounds from brahmi or (iii) providing novel synergistic formulations for therapeutics in various human ailments, according to "Exploring the role of "Brahmi" (Bocopa monnieri and Centella asiatica) in brain function and therapy" by Shinomol GK, Muralidhara, Bharath MM.(5)

6. Antibacterial and antifungal properties
In the assessment of 6-benzyladenine (BA) either alone or in combination with 1-naphthalene acetic acid (NAA) supplemented in Murashige and Skoog (MS) medium at different concentrations produced good quality callus from leaf explants of C. asiatica, indicated that the present investigation reveals that non-embryogenic callus can be turned into embryos and plantlets if cultured on appropriate medium. Furthermore, callus from leaf explant of C. asiatica can be a good source for production of antimicrobial compounds through bioreactor, according to "Regeneration of Centella asiatica plants from non-embryogenic cell lines and evaluation of antibacterial and antifungal properties of regenerated calli and plants" by Bibi Y, Zia M, Nisa S, Habib D, Waheed A, Chaudhary FM.(6)

7. Antioxidant capacity
In the identification of antioxidant effects of C. asiatica was exposed to various fermentations: no fermentation (0 min), partial fermentation (120 min) and full fermentation (24 h). Total phenolic content (TPC) and ferric-reducing antioxidant power (FRAP) of C. asiatica, found that C. asiatica herbal teas should be prepared at 100 °C for 10 min to obtain the optimum antioxidant capacity. Multiple brewing steps in C. asiatica herbal tea are encouraged due to the certain amount of antioxidant obtained, according to "Antioxidant capacity and phenolic composition of fermented Centella asiatica herbal teas" by Ariffin F, Heong Chew S, Bhupinder K, Karim AA, Huda N.(7)
8. Skin-Protective Activities
In the demonstration of Aqueous extracts of Centella asiatica L. Urban and its skin-Protective effects found that the skin-protective activities of C. asiatica were significantly improved through the nano-encapsulation process. These findings also imply that a crude extract can be used and have the same efficacy as purified compounds, which should reduce the purification process and production costs, according to 'Enhancement of the Skin-Protective Activities of Centellaasiatica L. Urban by a Nano-encapsulation Process" by Kwon MC, Choi WY, Seo YC, Kim JS, Yoon CS, Lim HW, Kim HS, Ahn JH, Lee HY.(8)

9. Scleroderma
In the testing Titrated extract of Centella asiatica (TECA)(a drug used in treatingsystemic scleroderma, is poorly water-soluble) and its effect on systemic scleroderma found that these three TECA micellar formulations prepared with Tween 20 and Tween 85 improved the solubility of TECA and reduced pain following injection, possibly due to the decrease in osmotic pressure. Thus, these micellar formulations composed of optimum ratios of Tween 20 and Tween 85 may have a potential as dosage forms for the intramuscular injection of a poorly water-soluble TECA, according to 'Development of a novel dosage form for intramuscular injection of titrated extract of Centella asiatica in a mixed micellar system" by Kim C, Hwang YY, Chang JY, Choi HG, Lim SJ, Lee MK.(9)

10. Wound healing
In the investigation of Effects of oral and topical administration of an alcoholic extract of C. asiatica on rat dermal wound healing found that the extract treated wounds were found to epithelialise faster and the rate of wound contraction was higher, as compared to control wounds. The results show that C. asiatica produced different actions on the various phases of wound repair, according to "Effects ofCentella asiatica extract on dermal wound healing in rats" by Suguna L, Sivakumar P, Chandrakasan G.(10)

11. Prevention of edema and microcirculation alterations
in the evaluation of the effects of TTFCA (total triterpenic fraction of Centellaasiatica) microcirculatory alterations associated with edema in passengers travelling for more than 3 hours found that ankle swelling (RAS) and edema were significantly lower in the TTFCA-treated group (p<0.025). The progressive increase in RAS, transcutaneous PCO2, and the decrease in VAR and O2 were linearly associated with flight time (up to 10 hours), according to "Flight microangiopathy in medium- to long-distance flights: prevention of edema and microcirculation alterations with total triterpenic fraction of Centella asiatica" by Cesarone MR, Incandela L, De Sanctis MT, Belcaro G, Geroulakos G, Griffin M, Lennox A, Di Renzo AD, Cacchio M, Bucci M(11)

12. Reproductive health
In the assessment of Centella asiatica and its beneficial effects of on lead-induced oxidative stress and suppressed reproductive performance in male rats found that co-administration of aqueous extracts of C. asiatica to lead exposed rats showed a significant increase in the weights of reproductive organs, reduction in lead-induced oxidative stress in the tissues and improvement in selected reproductive parameters over lead-exposed rats indicating the beneficial role of C. asiatica to counteract lead-induced oxidative stress and to restore the suppressed reproduction in male rats, according to "Protective role of Centella asiatica on lead-induced oxidative stress and suppressed reproductive health in male rats" by

Sainath SB, Meena R, Supriya Ch, Reddy KP, Reddy PS.(12)

13. Etc.


Side Effects
1. Do not use the herb in children or if you are pregnant without approval of the related field specialist
2. It may cause allergic effects
3. Overdose may cause nervous tension, such as headache, stomach upset, nausea, dizziness, etc.
4. Gotu Kola may interact with other medication, including water pills, anssedatives agents
5. Do not use the herb if you have any form of liver diseases
6. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22135869
(2) http://www.ncbi.nlm.nih.gov/pubmed/22135867
(3) http://www.ncbi.nlm.nih.gov/pubmed/22112723
(4) http://www.ncbi.nlm.nih.gov/pubmed/22092576
(5) http://www.ncbi.nlm.nih.gov/pubmed/22074576
(6) http://www.ncbi.nlm.nih.gov/pubmed/21989222
(7) http://www.ncbi.nlm.nih.gov/pubmed/21987075
(8) http://www.ncbi.nlm.nih.gov/pubmed/21893113
(9) http://www.ncbi.nlm.nih.gov/pubmed/11376976
(10) http://www.ncbi.nlm.nih.gov/pubmed/9246912
(11) http://www.ncbi.nlm.nih.gov/pubmed/11666121
(12) http://www.ncbi.nlm.nih.gov/pubmed/21843793

Most Common Diseases of Men of 50Plus - Erectile Dysfunction - Understand Viagra, Cialis, Levitra and Your Health

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

With either mental or physical stimulation, your brain signals the nerve ending in the penis to release nitric oxide. Nitric oxide relaxes or dilates blood vessels, enabling them to open up and bring more blood to the penis and helping to create an erection. In this article, we will discuss the effects of viagra, cialis and levitra, and your health. Please do not assume that you are healthy. In fact, erectile dysfunction and low sexual desire are good indications of some kind of sickness in your body. Please consult with you doctor before taking viagra, cialis and levitra.

1.Viagra
A drug used to treat erectile dysfunction. Viagra contains phosphodiesterase inhibitors, also called sildenafil, helping to dilate small blood vessels and relaxes muscles of the penis resulting in stronger and harder erection. Viagra's effects happen in 30 minutes and last for 5 hours.
Since Viagra helps to increase blood flow to the penis , it is easy to understand if overdosed, it may cause blood vessels to rupture especially small blood vessels in the eyes and cause danger to people with clogged arteries (high levels of cholesterol), high blood pressure and diabetes because of hardening and thickening arterial walls.
Here are some side effects of Viagra: flushing, headaches, nasal congestion, blurred vision, and dizziness.

2.Cialis Cialis contains the ingredient tadalafil which belongs to a group of medicines called phosphodiesterase type 5 inhibitor. Following sexual simulations, cialis tadalafil works by helping nitric oxide relax or dilate blood vessels, enabling them to open up and bring more blood to the penis and helping to create an erection. Cailis is used to treat men who experience difficulty having and maintaining an erection to orgasm.
Cialis works in as quickly as 30 minutes and lasts for about 36 hours while Viagra effect lasts up to 5 hours. Cialis is not affected by food or beverages.
Same as Viagra, if you have high cholesterol levels there is a good chance that some of the blood vessels in your penis are being clogged up, therefore increasing the blood flow to the blood vessels causes more harm than good may result in ruptured vessels and heart disease.
If you have high blood pressure, increased blood flow will cause your heart to work harder and may result in heart disease.
It is the same for people with diabetes. The side effects of Cialis includes shortness of breath, and wheezing or difficulty breathing.

3. LevitraLevitra contains vardenafil and is an oral therapy for the treatment of erectile dysfunction. Vardeanfil relaxes muscles and increases blood flow to the penis resulting in firming of erection. You take Levitra right before you want to have sex. Within about an hour, you will be able to get an erection in 16 minutes and wears off 6 hours after.
If you have high blood pressure, diabetes and high levels of cholesterol Levita may do more harm to your body because high blood pressure and diabetes causes your heart to work harder in providing blood flow to the penis, any arteries and blood vessels clogged up (caused by high cholesterol build up) will result in damage to your heart.
Side effects include facial flushing, indigestion or upset stomach, inflammation of the sinuses, dizziness, and flu like symptoms.

It would be better for your health to treat high blood pressure, high levels of cholesterol and manage your glucose level first before taking any of the above medications.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Erectile Dysfunction
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The Fertility Herb White willow

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

  The prevention and management In Herbal Medicine

Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
Reduce fat intake less than 30% of total calories with a low proportion of saturated fat and high in fiber from predominantly low-glycaemic-index-carbohydrate foods for patients with PCOs(827a). Calorie intake should be distributed between several meals per day with restricted intake of snacks and drinks(828).

             The Fertility Herb: White willow

White willow is also known as salix alba in herbal medicine, native to Europe and western and central Asia, used in traditional medicine as pain reliever(1007)(1008), anticancer(1009)(1010), antimicrobial(1013), antioxidant(1014)(1015), anti-inflammatory(1011)(1012) and fertility enhancing herb(1016).

1, Antiestrigenic effects
White willow processes antiestrigenic effects(1017) by blocking proliferation in hypersensitive cells (1018) which cause estrogenic diseases, including breast cancer(1019) and metabolism imbalance(1020) diseases, such as obesity and diabetes(1021).

2. Salicylic acid
Salicylic acid, a chemical compound converted from salincin found abundantly in white willow has shown to process anti acne(1022)(1023) one of many symptoms of PCOs) effects, probably through its antioxidant activity(1026) in blocking elevated production of sebum by hyperactive sebaceous glands and blockage of the follicle(1022). According to Telemark Hospital, the acid may also be beneficiary for increased the clinical pregnancy rate when used conjunction with vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI)(1024) and protective against fetal losses(1025), through its anti antithrombotic property(1025). The synthetic version of salicylic acid has also shown to consisting aspirin's cardioprotective effects through its antithrombotic and anti-inflammatory actions(1027).

3. Immune system
The antioxidant(1028)(1029) and anti inflammatory(1030)(1031) effects of white willow enhance immune system fighting against microbial invasion and guarding our body DNA integrity(1033) against irregular cell growth(1032)(1033) through inhibiting the effect of intermediate enzymes and other mechanisms(1027)

d. Vitamin C
Natural vitamin polypeptide C white willow found in white willow not only is found to consist the weight loss property(See the weight loss vitamin C)[
Vitami C found abundantly in red clover has shown strong evidneces epidemiologically in reducing weight loss for obese population, espexially for obese women with PCOs.

See The weight loss vitamin C for more details
[Vitamin C and other nutrients deficiency not only is associated to the risk of Obesity(807) but also enhances the risk of lipids, inflammation and insulin resistance(808).
According to the research team at Universidad Autónoma de Querétaro, there is an associated link between Obesity and Zinc and vitamins A and C concentration in in women from rural Mexico, in a fasting blood sample analysis (809).
Although genetic susceptibility to obesity is associated with gene polymorphisms affecting biochemical pathways which also impacted by specific foods and nutrients. According to Dr. Johnston CS., vitamin C depletion is associated to positively related to body mass, individuals with adequate vitamin C status oxidize 30% more fat during a moderate exercise bout than individuals with low vitamin Cstatus(810)

Vitamin C, the protective effect against obesity
Endothelial dysfunction has found to be associated to the incidence of obesity(811). The study of 76 healthy subjects (50 men and 26 women aged 21-45 years) obese subject, showed a positive effect of vitamin Cand indomethacin in reduced oxidative stress contributed to endothelial dysfunction in human obesity(812).
In the evaluation of the potential inhibitory activity on α-glucosidase and pancreatic lipase by Citrus spp. fruits of Spanish origin, grapefruit, contained higher contents of phytochemicals such as vitamin C, is found to have a great value for nutrition and treatment of diet-related diseases(813).
L-Ascorbic acid in the study, whether would facilitate the anti-obesity effects of chitosan and psyllium husk in vivo, showed addition of vitamin C in diet influenced the reduction in body weight gain and food efficiency ratio, and the increase in total fecal weight and fecal fat excretion in guinea pigs fed a high-fat diet(814)]
but also improves the immune function in fighting against the forming of free radicals(1034) and foreign invasion(1035) but also increases the blood flow to the reproductive organ(1036)(1037)(1038) through reducing oxidant stress, increasing NO bioavailability(1037) of which may reduce risk sexual libido(1038) and enhance the chance of conception(1039)(1040)(1041).


Side effects
1. Risk of anaphylactic reaction to patients with a history of allergy to salicylates(1042).
2. Over dose of white willow may cause digestive disorder such as nausea and stomachache(1044)
3. Do not use the herb(1043)
a. If you are aspirin allergy/sensitivity,
b. If you are taking anticoagulants or "blood thinners," and
c. On children with flu-like symptoms or Reye's syndrome.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(827a) Diet and nutrition in polycystic ovary syndrome (PCOS): pointers for nutritional management by Farshchi H, Rane A, Love A, Kennedy RL(PubMed)
(828) The optimal diet for women with polycystic ovary syndrome? by Marsh K, Brand-Miller J.(PubMed)
(1009) In vitro anti-proliferative effects of the willow bark extract STW 33-I by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1010) Willow leaves' extracts contain anti-tumor agents effective against three cell types by El-Shemy HA1, Aboul-Enein AM, Aboul-Enein KM, Fujita K.(PubMed)
(1011) Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract by Khayyal MT1, El-Ghazaly MA, Abdallah DM, Okpanyi SN, Kelber O, Weiser D.(PubMed)
(1012) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress by Sharma S1, Sahu D, Das HR, Sharma D.(PubMed)
(1013) Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds by Rauha JP1, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H, Vuorela P.(PubMed)
(1014) The study of interactions between active compounds of coffee and willow (Salix sp.) bark by water extract. Durak A1, Gawlik-Dziki U1.(PubMed)
(1015) Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans by Ishikado A1, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell TK, Makino T.(PubMed)
(1016) What Your Doctor May Not Tell You About(TM) Getting Pregnant: Boost Your ... By Raymond Chang, Elena Oumano
(1017) antiestrigenic effectsof bee pollen from Cystus incanus and Salix alba as evaluated by the yeast estrogen screen and the micronucleus assay in human lymphocytes by Pinto B1, Caciagli F, Riccio E, Reali D, Sarić A, Balog T, Likić S, Scarpato R.(PubMed)
(1018) Adaptive hypersensitivity to estrogen: mechanisms and clinical relevance to aromatase inhibitor therapy in breast cancer treatment by Santen RJ1, Song RX, Zhang Z, Kumar R, Jeng MH, Masamura S, Lawrence J Jr, MacMahon LP, Yue W, Berstein L.(PubMed)
(1019) Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues by Shenker NS1, Flower KJ2, Wilhelm-Benartzi CS3, Dai W4,5, Bell E6, Gore E7, El Bahrawy M8, Weaver G9, Brown R10, Flanagan JM11.(PubMed)
(1020) Sex hormone imbalances and adipose tissue dysfunction impacting on metabolic syndrome; a paradigm for the discovery of novel adipokines by Zhang H, Sairam MR.(PubMed)
(1021) Metabolic Balance for Maximum Health 6/06 June 6, 2006 - - + Juvenon Health Journal Vol. 5 No. 6, June 2006
(1022) [Use of organic acids in acne and skin discolorations therapy].[Article in Polish]by Kapuścińska A1, Nowak I1.(PubMed)
(1023) Rapid treatment of mild acne with a novel skin care system containing 1%salicylic acid, 10% buffered glycolic acid, and botanical ingredients by Bhatia AC, Jimenez F.(PubMed)
(1024) Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI by Hanevik HI1, Friberg M, Bergh A, Haraldsen C, Kahn JA.(PubMed)
(1025) Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss by Giancotti A1, La Torre R, Spagnuolo A, D'Ambrosio V, Cerekja A, Piazze J, Chistolini A.(PubMed)
(1026) Clinical evidence on the efficacy and safety of an antioxidant optimized 1.5% salicylic acid (SA) cream in the treatment of facial acne: an open, baseline-controlled clinical study by Zheng Y1, Wan M, Chen H, Ye C, Zhao Y, Yi J, Xia Y, Lai W.(PubMed)
(1027) Molecular targets of aspirin and cancer prevention by Alfonso L1, Ai G2, Spitale RC3, Bhat GJ2.(PubMed)
(1028) Effects of salicylic acid and putrescine on storability, quality attributes andantioxidant activity of plum cv. 'Santa Rosa' by Davarynejad GH1, Zarei M1, Nasrabadi ME1, Ardakani E1.(PubMed)
(1029) Salicylic acid promotes seed germination under high salinity by modulatingantioxidant activity in Arabidopsis by Lee S1, Kim SG, Park CM.(PubMed)
(1030) An in vivo study examining the antiinflammatory effects of chamomile, meadowsweet, and willow bark in a novel functional beverage by Drummond EM1, Harbourne N, Marete E, Jacquier JC, O'Riordan D, Gibney ER.(PubMed)
(1031) Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark by Drummond EM1, Harbourne N, Marete E, Martyn D, Jacquier J, O'Riordan D, Gibney ER.(PubMed)
(1032) Willow bark extract (BNO1455) and its fractions suppress growth and induce apoptosis in human colon and lung cancer cells by Hostanska K1, Jürgenliemk G, Abel G, Nahrstedt A, Saller R.(PubMed)
(1033) In vitro anti-proliferative effects of the willow bark extract STW 33-I. by Bonaterra GA1, Kelber O, Weiser D, Metz J, Kinscherf R.(PubMed)
(1034) Comprehensive study on vitamin C equivalent antioxidant capacity (VCEAC) of various polyphenolics in scavenging a free radical and its structural relationship by Kim DO1, Lee CY.(PubMed)
(1035) Structure, mechanism and regulation of an artificial microbial ecosystem forvitamin C production by Zou W1, Liu L, Chen J.(PubMed)
(1036) Melatonin and vitamin C increase umbilical blood flow via nitric oxide-dependent mechanisms by Thakor AS1, Herrera EA, Serón-Ferré M, Giussani DA.(PubMed)
(1037) Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat by Yan J1, Tie G, Messina LM.(PubMed)
(1038) Protective role of ascorbic acid to enhance reproductive performance of male rabbits treated with stannous chloride by Yousef MI1.(PubMed)
(1039) Efficacy of vitamin C and ethanolic extract of Sesamum indicum in promoting fertility in male Wistar rats by Ashamu E1, Salawu E, Oyewo O, Alhassan A, Alamu O, Adegoke A.(PubMed)
(1040) Vitamin C--the primate fertility factor? by Millar J1.(PubMed)
(1041) Promoting extracellular matrix remodeling via ascorbic acid enhances the survival of primary ovarian follicles encapsulated in alginate hydrogels by Tagler D1, Makanji Y, Tu T, Bernabé BP, Lee R, Zhu J, Kniazeva E, Hornick JE, Woodruff TK, Shea LD.(PubMed)

Most Common Diseases of 50Plus:The Research and Studies of Ischemic heart disease - Treatments In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
                                      Cardiovascular Disease


Cardiovascular disease is defined as medical conditions affecting the cardiovascular system, including heart, blood vessels(arteries and veins).
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
There are many causes of heart diseases. Most of heart diseases are caused by high blood pressure contributes to hardening of the arteries. High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat. All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.

                   Ischemic heart disease
Ischemic heart disease is defined as a condition of reduced blood supply of the heart muscle, as a result of coronary artery disease caused by plague building up in the arteries.

                            The Treatments

In conventional medicine perspective
1. Medical treatments
1. 1. Nitroglycerin
a. Nitroglycerin is used to treat ischemic cardiac pain. and improve blood flow to the heart. Transdermal nitrate delivery systems improve the quality of life in ambulant patients: anginal attacks are reduced with a minimum of side effects. The widespread acceptance of this novel form of drug delivery has stimulated its application in other therapeutic avenues. The efficacy of transdermal nitroglycerinin the suppression of silent ischemic attacks has been demonstrated(60)
b. Side effects are not limit to
b.1. Dizziness
b.2. Lightheadedness, or fainting when sitting up or standing
b.3. Flushing of face and neck
b.4. Headache
b.5. Irritation
b.6. Nausea
b.7. Vomiting
b.8. Etc.

1.2. Beta-blockers
a. Beta blocker has been used to lower heart rate, blood pressure, and enhance oxygen to the heart. In the study of The 248 cases presented with new coronary heart disease from 1982 through 1984, and the 737 controls were a probability sample of health maintenance organization patients free of coronary heart disease. A withdrawal syndrome immediately following the cessation of beta-blocker use may be an acute precipitant of angina and myocardial infarction in hypertensive patients who have no prior history of coronary heart disease(61).
b. Side effects are not limit to
b.1. the medicine can cause allergic reaction to certain people, such as: rash, itching, swelling, dizziness, trouble breathing.
b.2. Easy bruising or bleeding,
b.3. Swollen hands or feet,
b.4. Confusion,
b.5. Depression
b.6. Etc.

1.3. Calcium channel blockers
a. The medicine used to relax arteries, lower blood pressure, and reduce strain on the heart. Researchers suggested that Compared with clopidogrel without calcium-channel blockers (CCBs), clopidogrel with CCB does not increase the mortality or composite thromboembolic events in elderly CAD patients, but clopidogrel combined with nondihydropyridine CCB is associated with significantly increased composite thromboembolic events in comparison with dihydropyridine CCB(62).
b. Side effects are not limit to
b.1. Stomach pain
b.2. Constipation
b.3. Drowsiness
b.4. Fatigue Feelings of a rapidly or forcefully beating heart (palpitations)
b.5. Flushing or hot flashes
b.6. Headaches
b.7. Nausea
b.8. Etc.

1.4. Statins
a. The medicine used to lower cholesterol. Dr. Biasucci LM, and the scientists at the Sacro Cuore University, in the study ofStatins and coronary artery disease:clinical evidence and future perspective said
"The introduction of more powerful statins in the market offered the opportunity to study whether an intensive lipid lowering treatment could yields even better cardiovascular outcomes than a moderate statin therapy and several clinical trial confirmed this hypothesis. Statins have also pleiotropic effect behind their lipid lowering function: they reduce inflammation, which plays an important role in the atherosclerotic process"(63).
b. Side effects are limit to
b.1. Headache
b.2. Nausea
b.3. Vomiting
b.4. Constipation
b.5. Diarrhea
b.6. Weakness
b.7. Muscle pain
b.8. Etc.

1.5. Aspirin
a. Many researchers believe that daily intake aspirin can reduce the risk of blood clots from forming in your arteries. In the study to determine the cardiovascular and coronary risk thresholds at which aspirin for primary prevention of coronary heart disease is safe and worthwhile, Dr. Sanmuganathan PS and the research team at the Royal Hallamshire Hospital, indicated that Aspirin treatment for primary prevention is safe and worthwhile at coronary event risk >/= 1.5%/year; safe but of limited value at coronary risk 1%/year; and unsafe at coronary event risk 0.5%/year. Advice on aspirin for primary prevention requires formal accurate estimation of absolute coronary event risk(64).
b. Side effects are not limit to
b.1. Stomach pains
b.2. Feelings of nausea
b.3. Vomiting.
b.4. Allergic reaction to some people
b.5. Aspirin may interact with other medicine, such as blood thinning medicine
b.6. Etc.

2. Percutaneous Coronary Intervention (PCI )
Percutaneous Coronary Intervention (PCI ) is one therapeutic treatment used to treat the narrowed coronary arteries of the heart found in coronary heart disease and Ischemic heart disease.
In study of a total of 282 patients (74.1% females) with mean age of 57.0±3.2 years were studied. Most of the patients (89.7%) underwent elective PCI. Angiographic and procedure success rates were 95.7% and 94.6%, respectively. In-hospital MACE included two cases of death (0.7%) and one MI (0.3%); 2/29 (6.9%) of the emergent PCI and 1/253 (0.4%) of the elective PCI cases. MACE during follow-up included three cases of death (1.0%) and two MI (0.7%); 2/252 (0.8%) of the elective PCI and 1/28 (3.5%) of the emergent PCI cases. The overall MACE was calculated as 8 cases (2.8%) which included 5/29 (17.2%) of the emergent and 3/253 (1.1%) of the elective cases; P<0.001, concluded that PCI is performed with an acceptable success rate in our center in Isfahan and mortality and complications are within the range reported by other highly specialized centers in IRAN. Further studies with larger sample size are needed to find predictive factors(65).

3. Coronary revascularisation
Coronary artery bypass grafting (CABG)
Coronary artery bypass grafting (CABG) is a surgical procedure performed to reduce the risk of death from coronary artery disease by bypass atherosclerotic narrowings as arteries or veins from elsewhere in the patient's body are grafted to the coronary arteries to improve the blood supply to the heart muscle. some researchers suggested that transthoracic echocardiography(TEE) prior to coronary artery bypass surgery can provides higher resolution images than transthoracic echocardiography (TTE). Therefore one can conclude that TEE is the imaging modality of choice for detecting aortic atheromatous plaques but in patients with low risk for stroke and aortic atheromas, a detailed TTE may be sufficient for the pre-operative assessment(66).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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Sources
(61) http://www.ncbi.nlm.nih.gov/pubmed/1968518
(62) http://www.ncbi.nlm.nih.gov/pubmed/22543122
(63) http://www.ncbi.nlm.nih.gov/pubmed/22495163
(64) http://www.ncbi.nlm.nih.gov/pubmed/11179262
(65) http://www.ncbi.nlm.nih.gov/pubmed/22577441
(66) http://www.ncbi.nlm.nih.gov/pubmed/22614701


The Obesity's Weight Loss Recipes: Fancy rice salad

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.





Recipe attributed to Company's Coming Salads by Jean Parè

Turn leftover rice into this yummy dish. Serve on lettuce with a roll

Cooked rice, cold 1 cup (250ml)
Crushed pineapple, drained4 oz. (398 ml)
Granulated sugar 1/4 cup (50ml)
Whipping cream ( or 1 envelope topping) 1 cup (250 ml)
Salad dressing ( or Mayonnaise) 1/4 cup (50ml)
Lettuce
Maraschino cherries
Combine rice, pineapple and sugar in a bowl. Stir
Beat cream until stiff. Beat in salad dressing. Fold into rice mixture.
Arrange lettuce on plates. Spoon salad in center. Top with a cherry. Serve 6.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet


Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Most Common Disease of 50-plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalgia Arthritis (Rheumatica): The Individual herbs - Boswellia serrata

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                 Polymyalgia Arthritis (Rheumatica)


Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.

                             Treatments


B.2. Herbal and Traditional Chinese medicine

Herbal medicine from different cultures have been found effectively in reduced symptoms and treatment for patient with Polymyalagia Arthritis (Rheumatica), including
9. Boswellia serrata
Boswellia serrata used as incense in religious and cultural ceremonies and in medicine over thousands of year may be the potential source for treatment of osteoarthritis due to its anti inflammatory(472,227), anti-arthritic and analgesic activity activity(473,228) in decreased knee pain, increased knee flexion and increased walking distance(473,228).
DR. Kizhakkedath said that formula containing Curcuma longa and Boswellia serrata extracts (CB formulation) at 500 mg administered twice a day in a directly compared with the selective COX-2 inhibitor, celecoxib at 100 mg twice a day, induced more successful symptom scoring and clinical examination(475,229).

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months


Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer


References
(472,227) Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview by M. Z. Siddiqui(PMC)
(473,228) Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial by Kimmatkar N1, Thawani V, Hingorani L, Khiyani R.(PubMed)
(475,229) Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis by Kizhakkedath R1.(PubMed)

The Obesity' Research and Studies - The ketogenic diet: an underappreciated therapeutic option

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

The ketogenic diet is defined as a a special diet with high-fat, low-carbohydrate diet thathas been use as treatment to control seizures in some people with epilepsy.
In the review of Obesity as a epidemic proportions in Western countries and its strong risk factor for cardiovascular disease, found that most studies show that ketogenic diet or VLCKD (very low carbohydrate ketogenic diet) has a solid physiological and biochemical basis which is able to induce effective weight loss and improvement of several parameters of cardiovascular risk(1)

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity 
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

(1)" [The ketogenic diet: an underappreciated therapeutic option?]." [Article in Italian]by Paoli A, Canato M, Toniolo L, Bargossi AM, Neri M, Mediati M, Alesso D, Sanna G, Grimaldi KA, Fazzari AL, Bianco A