Thursday, September 1, 2016

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Ma Chi Xian (herb portulacae oleraceae)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
          Ma Chi Xian (herb portulacae oleraceae)

Ma Chi Xian is also known as Pigweed. The sour and cold herb has been used in TCM as antibiotic, anti-hypertensive and anti tumors and to promote contraction of uterus, prevent and treats dysentery, get rid of parasites , treat post partum bleeding, etc, as it clears Heat, expels toxins; cools Blood, stops bleeding, etc., by enhancing the functions of large intestine, liver chasubles.

Ingredients
1. Omega-3 fatty acid
2. Noradrenaline
3. Dopamine
4. Dopa
5. Galacturonic acid
6. β – Amyrin
7. Lupeol
8. Oxalic acid
9. Etc.

Health Benefits 
1. Analgesic and anti-inflammatory effects
In a review of the records in both folkloric and scientific literature, conducted by Zayed Complex for Herbal Research and Traditional Medicine, indicated that Portulaca has many medicinal uses. After our previous preliminary screening of three species of the family for analgesic and anti-inflammatory properties, Portulaca oleracea L. subsp. sativa (Haw.) Celak. (a cultivar) was chosen for further work due to its abundant availability from reliable sources. The 10% ethanolic extract of the aerial parts (dried leaves and stem) showed significant anti-inflammatory and analgesic after intraperitoneal and topical but not oral administration when compared with the synthetic drug, diclofenac sodium as the active control. Results indicate this cultivar species of Portulaca also possesses some of the claimed traditional uses of the wild species in the relief of pain and inflammation(1).

2. Diabetic endothelial dysfunction
In the study to investigate the protective effect of the aqueous extract of Portulaca oleracea L. (AP), an edible plant used as a folk medicine, on diabetic vascular complications. Dr. Lee AS and the research team at the Wonkwang University, showed that the insulin immunoreactivity of the pancreatic islets remarkably increased in AP treated db/db mice compared with untreated db/db mice. Taken together, AP suppresses hyperglycemia and diabetic vascular inflammation, and prevents the development of diabetic endothelial dysfunction for the development of diabetes and its vascular complications(2).

3. Hepatoprotective activity
In the study to investigate the hepatoprotective activity of the aqueous extract of the aerial parts of Portulaca oleracea (P. oleracea) in combination with lycopene against carbon tetrachloride induced hepatotoxicity in rats, showed that both the treatment groups showed hepatoprotective effect against carbon tetrachloride induced hepatotoxicity by significantly restoring the levels of serum enzymes to normal which was comparable to that of silymarin group(3).

4. Type-2 diabetes mellitus
In the study to investigate antidiabetic activity of purslane seeds on type-2 diabetic subjects and to provide scientific basis for the clinical use of Portulaca oleracea (PO), scientists at the Sana’a University, Madbah, Sana, indicated that PO seeds could be effective and safe as adjuvant therapy for Type-2 diabetic subjects. These results demonstrated that PO seeds possessed notable hypoglycaemic, hypolipidaemic and insulin resistance reducer effects; possibly due to its contents of polyunsaturated fatty acids, flavonoids, and polysaccharides(4).
5. Etc.

Side Effects
1. No not use the herb in case of spleen and stomach deficiency.
2. Do not use the herb in newborn, children, or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
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Overcome Infertility: Pene Trak test of Male Infertility In Conventional medicine Perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                    Overcome Infertility 

Infertility is defined as inability of a couple to conceive after 12 months of unprotected sexual intercourse. It effects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.

       Pene Trak test of  Male Infertility In Conventional medicine Perspective

I. Definition
Pene trak is a test for 90 minutes for checking the movement of sperm through a normal and friendly mucus in the test tube.

II. Procedure
Tested sperm is taken in the clinic laboratory through masturbation then the mixer of sperm and friendly mucus is examined through microscope.

III. Diagnosis
After a 90 minutes, the sample is observed through the microscope and the distance of the sperm have penetrated the mucus also is recorded. Failure of sperm to move a minimum distance is considered to have a poor chance for egg fertilizing and suggested a infertility problem for the testes sample couple. The inability of sperm to move a minimum distance through cervical mucus may be caused by immune antibody leading to the risk of infertilization.

IV. Risk
Ff the test is successful, it only increases the chance of fertility but does not guarantee the sperm will be free to fertilize the egg when it reach the Fallopian tube. Please make sure that other reproductive organs are already taking care for a healthy conceive.
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Children Health: Attention Deficit Disorder (ADHD/ADD) -Treatments In Herbal medicine perspective - Hawthorn

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Attention Deficit Disorder (ADHD/ADD)

Attention Deficit Disorder (ADHD/ADD) also known as attention deficit hyperactivity disorder is a chronic disease occurs in certain age and years of a children, defined as a condition with characteristics of co-existence of attentional problems and hyperactivity. It effects about 5% of the all children in the world with boys have 3-4 times higher risk than girl. Over one third of children with ADHD will have continued symptoms existed into their adult life.


                 The Herbal medicine - Hawthorn
a. Neuroprotective effects
In the investigation of the neuroprotective effects on PC12 cells from the methanol extracts of Spatholobus suberectus, Uncaria rhynchophylla, Alpinia officinarum, Drynaria fortunei, and Crataegus pinnatifida found that The CPE, SSE, and URE presented neurogrowth effects and neuroprotective activities on H(2)O(2)-induced PC12 cell death at 0.5-5.0 μg/mL. The CPE represents a promising medicinal plant source for the treatment of H(2)O(2)-induced neurodegenerative disease, because of its useful phytochemical characteristic, according to "Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts" by Chang CL, Lin CS, Lai GH.(84)

b. Immunomodulatory effect
In the determination of sheds more light on the extract's mechanism of neuroprotection, especially its immunomodulatory effect found that Hawthornextract helped alleviate pro-inflammatory immune responses associated with I/R-induced injury, boosted IL-10 levels, and increased Foxp3-positive T(regs) in the brain, which may have aided in suppression of activated inflammatory cells. Such treatment also minimizes apoptotic cell death by influencing STAT-3 phosphorylation and Bcl-xL expression in the brain. Taken together, the immunomodulatory effect of Hawthorn extract may play a critical role in the neuroprotection observed in this MCAO-induced stroke model, according to "Immunomodulatory effect of Hawthorn extract in an experimental stroke model" by Elango C, Devaraj SN.(85)

c. Prevention and treatment of cataracts
In the evaluation of the anticataract potential of Crataegus pinnatifida (hawthorntree) leaves and its extract in selenite-induced cataract in vivo and antioxidant effects in vitro, found that administration of C. pinnatifida leaves extract eye drops alternately three times a day in rat pups with selenite-induced oxidative stress significantly increased serum SOD and CAT activities, and tended to reduce MDA level compared with control group. The antioxidant enzyme SOD, CAT, and GSH activities in lens showed a significant increase. These results may be applied in the future for the prevention and treatment of cataracts, according to "Prevention effect in selenite-induced cataract in vivo and antioxidative effects in vitro ofCrataegus pinnatifida leaves" by Wang T, Zhang P, Zhao C, Zhang Y, Liu H, Hu L, Gao X, Zhang D.(86)
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Dietary Minerals Calcium: The dosage of calcium and life style risks

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                 Dietary Minerals 

Dietary Minerals are the group of minerals which is essential for our body to sustain normal functions and physical health.

                                      Calcium

Calcium, a trace mineral plays an important role in build and maintain strong bones and teeth, found abundantly in meat, poultry, fish, nut, seeds, bean, etc. As we age, calcium is absorbed less effectively.

      The dosage of calcium and life style risks

According to the study by Aarhus University, secondary hyperparathyroidism caused bycalcium and vitamin D insufficiency may reduce bone mass and strength and increase fracture risk and should be avoided. Since calcium supplementation has been associated with an increased risk of cardiovascular complications and renal stones, the dose should be tailored to the habitual daily calcium intake. Lifestyle-related risk factors (smoking, alcohol consumption, lack of physical activity and low body weight) should be addressed. The antifracture efficacy of antiresorptive and anabolic treatment for osteoporosis has not been documented in larger randomized controlled studies(5).
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Women Health: The Obesity and Polycystic ovary syndrome Research and Studies of Gene expression in visceral and subcutaneous adipose tissue of obese women with polycystic ovary syndrome (PCOS)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

Polycystic Ovarian Syndrome is defined as endocrinologic diseases caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries as resulting of enlarged ovaries, leading to hormone imbalance( excessive androgen), resulting in male pattern hair development, acne,irregular period or absence of period, weight gain and effecting fertility. It effects over 5% of women population or 1 in 20 women.

The Studies of  Gene expression in visceral and subcutaneous adipose tissue of obese women with polycystic ovary syndrome (PCOS)

 Masculinization of adipokine gene expression in visceral and subcutaneous adipose tissue of obese women with polycystic ovary syndrome (PCOS
Sex hormones, particularly androgens, may influence not only adipose tissue distribution but also its functions. In the study severely obese men (n = 7), control women (n = 7), and hyperandrogenic women presenting with polycystic ovary syndrome (PCOS) (n = 7) submitting to bariatric surgery and an independent series of 40 patients with PCOS and 40 control women matched for age and body mass index to assess the possibility of sexual dimorphism in adipose tissue and skeletal muscle function, posted in PubMed, indicated that expression of chemerin and lipocalin-2 was higher in VAT than in SAT in men and women with PCOS; the opposite was observed in control women. Omentin-1 expression was higher in VAT than in SAT in the three groups. No differences were observed in the skeletal muscle expression of these adipokines. Obesity increased serum chemerin and lipocalin-2 levels and tended to decrease omentin-1, irrespective of PCOS.
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Most Common Diseases of 50 Plus: Thyroid Disease : Euthyroid sick syndrome as a result of Sepsis - Treatments in TCM medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                         Thyroid disease


Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.


             Euthyroid sick syndrome as a result of Sepsis

Sepsis is defined as a condition caused by chemicals released into the bloodstream to fight the infection trigger inflammation throughout the body as a result of severe infection(a)(b). according to the study by the University of Utah, sepsis is the commonest cause of admission to medical ICUs across the world. Mortality from sepsis continues to be high. Besides shock and multi-organ dysfunction occurring following the intense inflammatory reaction to sepsis, complications arising from sepsis-related immunoparalysis contribute to the morbidity and mortality from sepsis(c).

                                              The Treatments

 Treatments in traditional Chinese medicine perspective
1. Cortex lycii Cortex lycii with both highest affinities was selected out from one hundred and fourteen traditional Chinese herbs. In subsequent experiments, chromatography was utilized and coupled with the biosensor to purify fractions with a higher affinity for LPS and CpG DNA. In line with affinity assay, these fractions were shown to neutralize LPS and CpG DNA and inhibit their activity in vitro and in vivo. Lastly, the contributing monomer Kukoamine B (KB) was purified. KB neutralized LPS and CpG DNA in vitro. It inhibited TLR4, TLR9 and MyD88 mRNA expressions up-regulated by LPS and CpG DNA, and also attenuated the LPS and CpG DNA elicited nuclear translocation of NF-κB p65 protein in RAW264.7 cells. It also protected mice from lethal challenge of heat-killed E. coli, a mixture of LPS and CpG DNA(66).

2. Magnolia officinalis
Magnolol is a compound extracted from the Chinese medicinal herb Magnolia officinalis. In the study to evaluate the effects of magnolol on sepsis induced by intravenous (i.v.) administration of lipopolysaccharide (LPS; 10 mg/kg) in anaesthetized Wistar rats with Magnolol (4 microg/kg, i.v.) was administered at 30 min after LPS injection, found that post-treatment with magnolol significantly attenuated the deleterious haemodynamic changes (e.g., hypotension and bradycardia) caused by LPS. Meanwhile, magnolol significantly inhibited the elevation of plasma levels of tumor necrosis factor alpha, glutamate-oxaloacetate transaminase, glutamate-pyruvate transaminase and blood urine nitrogen caused by LPS. The induction of inducible nitrous oxide (NO) synthase and the overproduction of NO and superoxide anions by LPS were also significantly reduced by post-treatment with magnolol. Moreover, the plasma level of the thrombin-antithrombin complex following administration of LPS was also reduced by post-treatment with magnolol(67).

3. Terminaliachebula Retz
Terminaliachebula Retz was found to possess the highest capability of binding lipid A. With CER (cation-exchange resin) and HPLC, the extracted from Terminaliachebula Retz, and named them TCR1, TCR2 and TCR3 respectively was found that the TCR3 was the most capable candidate to bind lipid A. We also studied the biological activities of TCR3 against sepsis in vitro and in vivo. in vitro, TCR3 could significantly inhibit LPS (lipopolysaccharide)-induced LAL (Limulus amoebocyte lysate)) from agglutination and decrease TNFalpha (tumour necrosis factor alpha) release from RAW264.7 cells induced by LPS in a dose-dependent manner. in vivo, TCR3 could significantly protect mice against a lethal challenge with LPS and heat-killed Escherichia coli 35218 in a dose-dependent manner(68).

4. Scutellaria baicalensis Georgi (Huang Qin)
2',5,6',7-tetrahydroxyflavanonol (THF) from S. baicalensis Georgi under the direction of neutralization of LPS and reducing proinflammatory cytokines. In vitro, THF directly bound to LPS and neutralized its activity. THF not only down-regulated TNF-alpha mRNA expression but also decreased TNF-alpha and IL-6 release from RAW264.7 cells induced by LPS in a dose-dependent manner. THF-mediated inhibition on proinflammatory cytokine release is probably associated with downregulation of LPS-induced TLR4 mRNA augmentation. In vivo, THF could significantly protect mice against a lethal challenge with heat-killed E. coli 35218 (E. coli 35218) in a dose-dependent manner, and decreased the plasma LPS level in endotoxemia mice, according to Third Military Medical University(69).
 
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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/9086580
(b)http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/thyroid_disorders/euthyroid_sick_syndrome.html
(c) http://en.wikipedia.org/wiki/Euthyroid_sick_syndrome
(d) http://www.ncbi.nlm.nih.gov/pubmed/8028742
(66) http://www.ncbi.nlm.nih.gov/pubmed/21073991
(67) http://www.ncbi.nlm.nih.gov/pubmed/20519137
(68) http://www.ncbi.nlm.nih.gov/pubmed/19203350
(69) http://www.ncbi.nlm.nih.gov/pubmed/18755299

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Women Health: Menstrual Disorders - Menorrhagia - The Causes and Risk Factors of Primary Menorrhagia

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Menorrhagia is defined as a condition of excessive bleeding in the menstruation phase of the menstrual cycle in the reproductive age of a woman leading to heavy blood loss that can interfere with the woman normal activities, as a result of disruption of normal hormonal regulation of periods or disorders of certain reproductive organs.


       The Causes and Risk Factors of Primary menorrhagia 

1. Age
Girl in their first 2 years of menstruation may be experience the adnominal cramps and pain and heavt period as a result of the immature of the reproductive organs. 

2. Increase arachidonic acid in endometrium
High amount of polyunsaturated omega-6 fatty acid may results in overproduction of the family2 series of eicosanoid, elading to thickening of endometrium, dilation of blood vessels. 

3. Hormone imbalance that prevent ovulation
Stress, infection, imbalance of neurotransmitter, under weight and accumulated toxic chemical may interfere with production of certain hormone which can disrupt ovulation and case menorrhagia. 

3. Vitamin A deficiency
Vitamin A, an antioxidant enhances the body immune system fighting the against the forming of free radicals to protect the normal cell reproduction and against damage. Deficiency of vitamin A is one of the factor for women who were experience heavy menstrual bleeding. 

4. Bleeding or platelet disorders
Abnormal process by which blood forms clots (coagulation) to prevent blood loss during menstruation can lead menorrhagia. 

5. Excess toxicity
Excessive toxibody may be resulted in heavy period as a result of the body of trying to remove toxins through the blood. 

6. Vitamin K deficiency
Vitamin K is blood coagulation. Normally produced by bacteria in the intestine, women with intestine diseases may not produce enough vitamin K to stop the heavy flowing of blood during menstruation. 

7. Anemia
Women with the type of anemia having red blood cells breaking down faster than normal people, may also have heavy flowing of blood during menstruation caused by regular blood flow and breaking off of red blood cells thereby, reducing the coagulation function. 

8. Stress
Women who cannot adjust to events in life that are stressful, or seem to be stressful in their mind causes hormone imbalance resulting in overproduction of either estrogen or progesterone. 
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