Wednesday, September 21, 2016

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Ren Dong Teng (Caulis Lonicerae)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
           Ren Dong Teng (Caulis Lonicerae)
Ren Dong Teng is also known as Japanese Honeysuckle Stem. The sweet and cold herb has been used in TCM as Anti-inflammatory and Anti-spasm agent and to enhance the heart function, lower blood cholesterol, etc. as it clears Heat, expels toxins, disperses Wind-Heat-Damp, calms pain, etc. by enhancing the functions of heart and lung channels.

Ingredients
1. Chlorogenic acid
2. Isochlorogenic acid
3. L:oganin
4. Secologanin dimethylacetal
5. Secologanin dimethylacetal
6. Vogeloside
7. Epi-vogeloside[2]
8. Hederagenin-3-O-α-L-rbinopyranoside
9. Hederagenin-3-O-β-D-glucopyranosyl(1→2)-α-L-arabinopyranoside
10. Hederagenin-3-O-α-L-arabinopyranosyl-28-O-β-D-glucopyranosyl(1→6)- β-D-glucopyranoside
11. Etc.


Health Benefits
1. Liver protective effects
In the study to investigate the Protective effects of 41 Taiwan crude drugs on rat hepatic injuries caused by carbon tetrachloride (CCl4) and alpha-naphthylisothiocyanate (ANIT)found that the methanol extracts of Elephantopi Herba and Lonicerae Flos inhibited the release of intrahepatic enzymes and histological changes by CCl4(1).

2. Phagocytosis
Twenty-six herbal preparations made from 24 medicinal herbs, categorized as antipyretics in Chinese materia medica, were tested in vitro to determine their effects upon phagocytosis of 32P-labelled Staphylococcus aureus by neutrophils isolated from bovine blood and milk, showed that when compared with PBSS (0.01 M phosphate buffered saline solution) controls, most of the herbs at high concentrations inhibited phagocytosis while at lower concentrations phagocytosis was increased. All 26 herbal preparations significantly increased blood neutrophil activity at their proper concentrations. The most active herbs in promoting blood neutrophil phagocytosis were observed for Herba verbenae, Flos chrysanthemi, Flos lonicerae, Radix sophorae flavescentis, Herba houttuyniae, Radix isatidis, Herba patriniae(2).

3. Inhibition of platelet activation
In the study to evaluate the effects of the polyphenolic compounds isolated from Lonicera japonica Thunb on platelet aggregation, platelet thromboxane biosynthesis and hydrogen peroxide-induced endothelial cell injury, showed that the inhibitory effect on platelet activation and the cytoprotective effect on hydrogen peroxide-induced cell injury may explain the possible role of polyphenolic compounds isolated from Lonicera japonica Thunb in maintaining vascular homeostasis(3).

4. Regulation of Proinflammatory Mediators
In teh study to investigate the anti-inflammatory mechanism of polyphenol components isolated from Korea L. japonica T. by nuclear factor-kappaB (NF-κB) and mitogen-activated protein kinases (MAPKs) pathway, indicated that that polyphenol components isolated from Korea L. japonica T. should have anti-inflammatory effect on LPS-stimulated RAW 264.7 cells through the decrease of proinflammatory mediators expression by suppressing NF-κB and p38 MAPK activity(4).

5. HepG2 Cells
In the study to investigate the anti-cancer and hepatic protective effect of Lonicera japonica Thunb. (L. japonica T.), found that Polyphenolic extract also decreased the expression of CDK1, CDC25C, cyclin B1, pro-caspases-3 and -9 and poly ADP ribose polymerase, and affected the levels of mitochondrial apoptotic-related proteins. The phosphorylation of extracellular signal-related kinase ½ (ERK 1/2), c-Jun N-terminal kinase (JNK), and p-38 mitogen-activated protein kinases (MAPKs) were increased in HepG2 cells treated with polyphenolic extract, whereas Akt was dephosphorylated. These results indicate that inhibition of PI3K/Akt and activation of MAPKs are pivotal in G2/M cell cycle arrest and apoptosis of human hepatocarcinoma cells mediated by polyphenolic extract(5).

6. Neuroprotective effects
in the investigation of the neuroprotective effects of Lonicera japonica THUNB. extract (LJ) on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in SH-SY5Y cells, showed that LJ has a potent anti-parkinsonism; this effect was mediated, at least in part, by inhibition of neurotoxicity, apoptotic cascade events, and oxidative stress via activation of MAPKs, PI3K/Akt, and NF-κB(6).

7. Etc.

Side Effects
1. Do not use in case of spleen deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.


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Women Health: Menopause - The Symptoms

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                      Menopause 

 Menopause is the defined as a condition in which a woman is in the transition stage of permanent cessation of the ovaries functions in egg production because of less production of estrogen and progesterone, signalling the end of the reproductive phrase a woman's life. In menopause, menstruation has become irregular and slowly stop overtime, but in some women, menstrual flow comes to a sudden halt.

                                          The Symptoms 


Most symptoms are caused by imbalance of female hormones as a result of less production of estrogen and progesterone.
1. Hot flashes
2. Insomnia
3. Night sweats
4. Decreased sexual libido
5. Depression and anxiety
6. Mood swing
7. Vaginal dryness
8.Vaginal infections
9. Irregular heartbeats
10. Urinary incontinence and burning sensation
11. Bone loss
12. Etc.

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Children's Health - Autism - Diagnosis in a Conventional Medicine Perspective

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                        Autism 

Autism is one of the most common forms of brain development disorder and one in 166 child is diagnosed with some forms of autism. Children who are diagnosed with autism tend to have weak immune system and auto immune problems. Autism is defined as medical condition in which a child has some of the following impairments
a) Speech
b) Social and communication skills
c) Limited interest
d) Repetitive behaviour 


     Diagnosis  in a Conventional Medicine Perspective


For the disease to be treated effectively, the conventional doctor first has to diagnose what causes the symptoms of the disease or diseases. It is helped by blood test, logical screen, psychological and physical examination, etc. The diagnosis of children with development disorder is always a stressful and time consuming road for both parent and children, because each doctor in conventional medicine mostly specializes in one field and can not make any suggestion outside of his or her professional judgement. You may be recommended to see other specialists if one found to be necessary. Since autism is complex disease, it requires a team of doctor before it can be diagnosed correctly and many wrong diagnosis have been done, leading to overwhelming pressure and time wasting to the parent and their children. Fortunately, many cases of autism have been correctly diagnosed and are treated accordingly.

To avoid wasting your time, here is the basic list of doctors and specialists who have been required for all children with development disorder to be diagnosed correctly:
a. Development and behaviour pediatrician
b. Paediatric neurologist
c. Children psychiatrist
d. Children psychologist
e. Speech and language pathologist
f. Occupational therapist
g. Physical therapist
h. Play therapist
i. Social worker
Some children may require more or less specialists than the list above in their road to find a cure, but we believe the list is a basic team for fast and corrected diagnosis.
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General Health: Duodenitis Prevention - The do`s and do not`s list

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                       Duodenitis

 Duodenitis is defined as a condition of inflammation in the lining of the duodenum,the first section of the small intestine.

                               Prevention - The do`s and do not`s list
1. Avoiding spicy foods
Prolonged intake spicy foods incinerates the risk of irritation and inflammation of the lining of stomach and duodenum.

2. Changes in food tolerance and lifestyle
If you develop Duodenitis as result of bacterial infection, changes in food tolerance and lifestyle can be helpful. The prevalence of food intolerance decreased from 71% to 44% among patients with peptic ulcer disease (PUD) (P < 0.0001) and from 76% to 63% among patients with duodenitis (G/D) (P = 0.09). Tolerance improved for coffee, orange juice, fried foods, spicy foods and fruits, according to the study by Haukeland University Hospital(17).

3. Quit smoking
In the study to investigate whether cigarette smoking has an additive effect on the clinical presentation and course of disease in Helicobacter pylori-positive dyspeptic patients, researchers at the Tel Aviv University, indicated that Gastric and duodenal ulcers were significantly less prevalent in non-smokers than in current or past smokers (gastric 1.8%, 4.1%, 6.3%; duodenal 39.8%, 50%, 51.4%, respectively) (P < 0.05). The incidence of gastrointestinal bleeding was significantly lower in non-smokers than in current or past smokers (7.1%, 8.1% and 20.7%, respectively) (P < 0.05). Bacterial density, as assessed by the UBT value in 244 patients, was higher in non-smokers (mean 352.3 +/- 273 units) than in past smokers (mean 320.8 +/- 199) or current-smokers (mean 229.9 +/- 162) (P < 0.05)(18).

4. Excessive alcohol drinking and stress
Excessive drinking and stress are associated with the risk of Duodenitis(19)(20).

5. Avoiding prolonged use of anti-inflammatory drugs, such as Ibuprofen and Aspirin
Prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil, Motrin), naproxen (Aleve), or aspirin, in some people, it can lead to irritation causes of inflammation in the lining of the duodenum(21).

6. Moderate exercise
Exercises can reduce stress at work and at home(22), thus, reducing the risk of Duodenitis.

7. Etc.
Sources
(17) http://www.ncbi.nlm.nih.gov/pubmed/12737441
(18) http://www.ncbi.nlm.nih.gov/pubmed/11344768
(19) http://www.ncbi.nlm.nih.gov/pubmed/12898897
(20) http://www.ncbi.nlm.nih.gov/pubmed/9479996
(21) http://www.ncbi.nlm.nih.gov/pubmed/18158085
(22) http://www.ncbi.nlm.nih.gov/pubmed/22988262


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General Health: Duodenal ulcers: The Diet

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                               Duodenal ulcers

Duodenal ulcers, a type of peptic ulcer is defined as a condition of a localized tissue erosion in the lining the duodenum as a result of bacteria Helicobacter pylori (H pylori) in most cases. According to the study by Department of Research, University Hospital, Basel, fasting gastrin and pepsinogen-I and -II concentrations were significantly higher in H pylori positive compared with H pylori negative subjects. Neither age nor sex affected basal gastrin and pepsinogen concentrations in H pylori negative subjects. Fasting gastrin, pepsinogen-I and -II concentrations in serum samples were similar in H pylori positive persons with no symptoms and those with duodenal ulcers suggesting that similar mechanisms are involved in increasing plasma concentrations of these variables in both populations. Hypergastrinaemia and hyperpepsinogenaemia are therefore probably secondary to active H pylori infection(1).

                                 The Diet



1. Honey
In the study to assess the antibacterial potential of various brands of honey sold in Muscat area on some isolates of H. pylori and to determine if there is any synergy between honey and amoxycillin or clarithromycin used in the treatment of H. pylori gastritis and duodenal ulcer, found that all honey samples produced growth inhibition zones with H. pylori no at dilution of honey but had different zone sizes at 1:2-1:8 dilutions. Black Forest honey had the highest antibacterial activity followed by Langnese honey. None of the honeys had a synergistic effect with either clarithromycin or amoxycillin(18).

2. Probiotics
Helicobacter pylori infection, a highly prevalent pathogen, is a major cause of chronic gastritis and peptic ulcer and a risk factor for gastric malignancies. Animal studies demonstrated that probiotic treatment is effective in reducing H. pylori-associated gastric inflammation. Seven of 9 human studies showed an improvement of H. pylori gastritis and decrease in H. pylori density after administration of probiotics. The addition of probiotics to standard antibiotic treatment improved H. pylori eradication rates (81% vs. 71%, with combination treatment vs. H. pylori-eradication treatment alone; chi(2)test: P=0.03). Probiotic treatment reduced H. pylori therapy-associated side effects (incidence of side effects: 23% vs. 46%, with combination therapy vs. H. pylori-eradication treatment alone; chi(2)test: P=0.04)(19).

3. Oat
Oat has been chosen as a substrate for fermentation because it contains 100 times more of membrane lipids (surfactants) than any other food, has a favorable amino acid pattern (rich in glutamine), and is rich in water-soluble, fermentable-fiber beta-glucans. More than 1000 isolates of human-specific lactobacilli have been studied. Some strains, especially those of plantarum type, have proven effective in colonizing the colonic mucosa, suppressing the potentially pathogenetic flora, and may have other probiotic effects as well(20).

4. Onion
According to the study by The National Onion Association, Onions functions as an antioxidant, deactivating molecules that are injurious to cells in the body. Research studies have shown quercetin to promote healing of stomach ulcers(21).

5. Etc.
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General Health: Eating Disorders - Anorexia nervosa - The Cause and Risk factors

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                               Eating disorders

Eating Disorders are defined as a group of abnormal eating habits associated to a person preoccupation weight, involving either insufficient or excessive food intake.

                                Anorexia nervosa


Anorexia nervosa is a type of eating disorder usually develop in the teen years and effect over 90% of female, because of excessive food restriction and irrational fear to become fat due the wrongly influenced media as attractiveness is equated to thinness.

                The Cause and Risk factors


A. Causes
Some researchers suggested that The most commonly mentioned perceivedcauses were dysfunctional families, weight loss and dieting, and stressful experiences and perceived pressure(12). Others showed that Eating disorders (EDs) manifest as abnormal patterns of eating behavior and weight regulation driven by low self-esteem due to weight preoccupation and perceptions toward body weight and shape and Several lines of evidence indicate that brain-derived neurotrophic factor (BDNF) plays a critical role in regulating eating behaviors and cognitive impairments in the EDs(13).

B. Risk factors
1. Virtue of thin-ideal internalization, body dissatisfaction
Dr. Stice E, and the researchers team at the Oregon Research Institute, in the treatment of Anorexia nervosa showed that there is evidence that selective prevention programs that target young women at elevated risk for eating pathology by virtue of thin-ideal internalization, body dissatisfaction, and negative affect produce significant larger intervention effects than do universal programs offered to unselected populations(14)

2. Gender
If you are girls and women, you are at higher risk to develop Anorexia nervosa, because of growing social pressures. In a community sample of young adults (n = 1,056) completed a questionnaire that contained the Drive for Thinness, Bulimia, and Body Dissatisfaction subscales of the Eating Disorder Inventory, as well as probes for inappropriate compensatory behaviors, excessive exercise, and episodes of binge eating, showed that Women had substantially elevated scores on all of the factors except excessive exercise, for which men had significantly higher scores(15).

3. Gene mutation
Mutation of certain genes can cause increased risk of Anorexia nervosa, but certain gene change have been rule out such as , but some have been confirmed including Allele 13 of the marker D11S911 as it is significantly over represented in the anorexia nervosa population suggesting that a mutation in linkage disequilibrium with this locus may form part of the genetic component of AN. Further work is now required to try to reproduce these data in a second independent cohort and to further characterise this region of the human genome(15). Others found the linkage regions on chromosomes 1, 3, and 4 (anorexia nervosa) and 10p (bulimia nervosa)(16).

4. Family history
If you parent or siblings Anorexia nervosa, you are at increased risk to develop the disease. In the tduy to evaluate 420 first-degree relatives of 14 patients withanorexia nervosa, 55 patients with bulimia, and 20 patients with both disorders, Dr. Hudson JI, and the research team showed that the morbid risk for affective disorder in the families of the eating disorder probands was similar to that found in the families of patients with bipolar disorder; but was significantly greater than that found in the families of patients with schizophrenia or borderline personality disorder. These results add to the growing evidence that anorexia nervosa and bulimia are closely related to affective disorder(17).

5. Loss Weight intentionally
Dr. Müller MJ, and the team of scientists suggested that In regard to clinical practice, dietary approaches to both weight loss and weight gain have to be reconsidered. In underweight patients (e.g., patients with anorexia nervosa), weight gain is supported by biological mechanisms that may or may not be suppressed by hyperalimentation. To overcome weight loss-induced counter-regulation in the overweight, biological signals have to be taken into account. Computational modeling of weight changes based on metabolic flux and its regulation will provide future strategies for clinical nutrition(18).

6. Stress
People who are at stress and anxiety for what ever reason are at higher risk toanorexia nervosa. There is a case of report of athirty-five-year-old woman suffering from anorexia nervosa visited our hospital complaining of severe general weakness. She was diagnosed with stress-induced cardiomyopathy and mural thrombus using a transthoracic echocardiogram(19).

7. Occupations
Certain occupation such as Athletes, actors and television personalities, dancers, and models are at higher risk of anorexia. In a detailed interview (the Eating Disorder Examination), models reported significantly more symptoms of eating disorders than controls, and a higher prevalence of partial syndromes of eating disorders was found in models than in controls. A body mass index below 18 was found for 34 models (54.5%) as compared with 14 controls (12.7%). Three models (5%) and no controls reported an earlier clinical diagnosis of anorexia nervosa. Further studies will be necessary to establish whether the slight excess of partial syndromes of eating disorders among fashion models was a consequence of the requirement in the profession to maintain a slim figure or if the fashion modeling profession is preferably chosen by girls already oriented towards symptoms of eating disorders, since the pressure to be thin imposed by this profession can be more easily accepted by people predisposed to eating disorders(20).

8. Etc.
Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(13) http://www.ncbi.nlm.nih.gov/pubmed/15209840
(14) http://www.ncbi.nlm.nih.gov/pubmed/22614677
(15) http://www.ncbi.nlm.nih.gov/pubmed/1502972
(16) http://www.ncbi.nlm.nih.gov/pubmed/17950174
(17) http://www.ncbi.nlm.nih.gov/pubmed/15785332
(18) http://www.ncbi.nlm.nih.gov/pubmed/16380317
(19) http://www.ncbi.nlm.nih.gov/pubmed/2323585
(20) http://www.ncbi.nlm.nih.gov/pubmed/15282695

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Tuesday, September 20, 2016

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Gou Qi Zi or Qi Zi (Fructus Lycii)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
           Gou Qi Zi or Qi Zi (Fructus Lycii)

Gou Qi Zi or Qi Zi is also known as wolfberry fruit. The sweet and neutral herb has been used in TCM as anti cancer agent and to treat sore back, leg, and stomach; improves night vision, blurred vision, diabetes, premature white hair, enhance immune system, lowers blood lipids, elevate level of testosterone, simulate estrogen etc., as it nourishes and tonifies Liver and Kidneys, improve vision, moistens the Lungs, etc., by enhancing the functions of liver, lung and kidney channels.

Ingredients
1. Betaine
2. β-sitosterol
3. Linoleic acid
4. Physalien
5. Cryptoxanthin
6. Atropine
7. Hyoscyamine
8. Scopoletin
9. Amino acids
10. Physalein
11. Zeaxanthin
12. Dipalmitate
13. Carotene
14. Etc.

Health Benefits
1. Cholesterol
In the comparison of herbal extract SR10 of Radix Astragali, Radix Codonopsis and Cortex Lycii and its effect on lipoprotein oxidation found that SR10 inhibited erythrocyte hemolysis with IC50 value at 0.25 mg/ml and significantly prolonged low-density lipoprotein oxidation in vitro. SR10 attenuated platelet derived growth factor-BB-induced vascular smooth muscle cell proliferation by promoting cell cycle arrest at G0/G1 phase as well as inhibiting vascular smooth muscle cell migration. according to “Suppression of low-density lipoprotein oxidation, vascular smooth muscle cell proliferation and migration by a herbal extract of Radix Astragali, Radix Codonopsis and Cortex Lycii” by Chan JY, Koon JC, Leung PC, Che CT, Fung KP.(a).

2. Cervical cancer
In the evaluation of the cytotoxic and antiproliferative effect of 2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) against cancer cells in wolfberry found that AA-2βG and vitamin C mediated antitumor activity by downregulating the expression of proteins involved in cell apoptosis and proliferation and consequently inducing Hela cell apoptosis and cell cycle arrest, suggesting that AA-2βG and vitamin C may share a similar mechanism of inducing Hela cell apoptosis, according to “Selective suppression of cervical cancer Hela cells by 2-O-β-D-glucopyranosyl-L-ascorbic acid isolated from the fruit of Lycium barbarum L” byZhang Z, Liu X, Wu T, Liu J, Zhang X, Yang X, Goodheart MJ, Engelhardt JF, Wang Y.(b).

3. Anticancer and immunomodulatory effects
In the classification of the anticancer effects of traditional Chinese medicine (TCM) used in cancer therapies found that major active ingredients, L. barbarum polysaccharides (LBP), scopoletin and 2-O-β-D: -glucopyranosyl-L: -ascorbic acid (AA-2βG), are found to have apoptotic and antiproliferative effects on cancer cell lines. Moreover, LBP also contributes to body’s immunomodulatory effects and enhances effects of other cancer therapies. It is not known whether there are any undesirable effects, according to “A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit” by Tang WM, Chan E, Kwok CY, Lee YK, Wu JH, Wan CW, Chan RY, Yu PH, Chan SW.(c).

4. Hypochlolesterolemic and antioxidative effects
In the researches of the hypocholesterolemic effect and potential of tyramine derivatives from Lycii Cortex Radicis (LCR), the root bark of lycium (Lycium chenese Miller) in reducing lipid peroxidation found that The level of liver cholesterol was significantly lower in LCR1 and LCR2 groups than HF-control. Serum levels of TBARS were significantly lower only in LCR2 group when compared with HF-control group. From the observed results, we concluded that LCR can be utilized as a hypocholesterolemic ingredient in combination with ginger, especially for functional foods, according to “Study on the hypochlolesterolemic and antioxidative effects of tyramine derivatives from the root bark of Lycium chenese Miller” by Cho SH, Park EJ, Kim EO, Choi SW.(d).

5. Liver inflammation and fibrosis
In the elavuation of the effects of water extracted Lycium barbarum and Rehmannia glutinosa (HE) on carbon tetrachloride (CCl(4))-induced liver injury in rats found that treatment with water extracted Lycium barbarum and Rehmannia glutinosa (0.05% and 0.15% for each) for eight weeks protects against necrotic damage, indicated by decreases in plasma ALT and AST activities, and suppresses liver fibrosis by down-regulation of liver inflammation in rats with CCl(4)-induced liver injury, according to “Hot water extracted Lycium barbarum and Rehmannia glutinosa inhibit liver inflammation and fibrosis in rats” by Wu PS, Wu SJ, Tsai YH, Lin YH, Chao JC.(e).

6. Testicular oxidative stress
In the determination of Lycium barbarum polysaccharides (LBP) and its protective effect against doxorubicin (DOX)-induced testicular toxicity confirmed that LBP effectively attenuated DOX-induced severe degenerative changes of seminiferous tubules. This study illustrated the capability of LBP in attenuating testicular oxidative stress and protecting testis-specific toxicity in DOX-exposed rats(f).

7. Etc.

Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/21513503
(b) http://www.ncbi.nlm.nih.gov/pubmed/20717715
(c) http://www.ncbi.nlm.nih.gov/pubmed/22189914
(d) http://www.ncbi.nlm.nih.gov/pubmed/22125678
(e) http://www.ncbi.nlm.nih.gov/pubmed/22083989(f)http://www.ncbi.nlm.nih.gov/pubmed/22016089

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