Cat's claw may be the next potential and pharmaceutical target to identify the next single ingredient for the treatment of osteoarthritis, some researchers found.
Osteoarthritis (OA) is a type of arthritis characterized by the breaking down of joint cartilage and underlying bone, leading to symptoms of joint pain and stiffness.
Most common causes of osteoarthritis (OA)in the Western world is the most common disease of people with an occupation of repetitive movements of the joints and obesity, the disease which has a strong and negative impact on the weight-bearing joints.
However, injuries to joints that were not healed properly at a younger age such as fracture, and ligament tears can also lead to osteoarthritis.
In response to the question of why? people with the same health conditions, some are susceptible to the onset of osteoarthritis, while some others do not. Researchers launched an investigation to examine the mutated genes associated with the risks of osteoarthritis.
In fact, the genetic bases of this disease do not follow the typical patterns of Mendelian inheritance but involving the alterations in multiple genes.
Among genes that have been scanned, genes associated with the collagen type II (COL2A1) coded for structural proteins of the extracellular matrix of the cartilage seem to have an important role to have the osteoarthritic process.
Other genes coded for the structural proteins of the extracellular matrix, some candidates present increased susceptibility to developing the disease, including COL9A2, COL11A1, COL11A2 or COMP (cartilage oligomeric matrix protein gene).
Dr., the lead author, after taking into account of co and confounders suggested "it seems clear that expression levels in osteoarthritic and healthy patients are different and that genetic inheritance is a factor that should be considered in the near future for diagnosing and treating osteoarthritis" and
"On the other hand, it is important to recognize the interaction between genetic and environmental factors (e.g. obesity, excessive stress on the joint articulation, or the type of occupation) as it can be critical in the clinical expression of the disease".
The finding clearly indicated that genetic mutations inherited from the parents are found to associate with the prevalent risk of the disease.
Cat's claw found in the tropical jungles of South and Central America, is a genus Uncaria, belonging to the family Rubiaceae.
The plant has been used in traditional medicine over two thousand years as a tonic, contraceptive, anti-inflammatory, and infectious agent, and to treat diarrhea, rheumatic disorders, acne, diabetes, cancer and diseases of the urinary tract, etc..
The chemical constituents of Cat's claw include ajmalicine, akuammigine, campesterol, catechin, carboxyl alkyl esters, chlorogenic acid, cinchonain, corynantheine, corynoxeine, daucosterol, epicatechin, harman, hirsuteine, hirsutine, iso-pteropodine, etc.
In the finding, a natural ingredient or whole food similar to those of conventional medicine with no side effects, researchers at the Case Western Reserve University examined the anti-inflammatory activity in a number of botanical plants including the cat's claw.
Selected plants in the study include some medicinal fruits and herbs - pomegranate, green tea, cat's claw, devil's claw, ginger, Indian olibanum, turmeric, and bananas.
In the analysis of the pivotal molecular targets involved in inflammation and the joint destruction processed for OA management, researchers found that chemical compounds isolated from herbal Cat' s claw demonstrated a strong effect in ameliorating the symptoms of pain, compared to other medicinal plants and fruits.
After taking into account co and confounders, including the limitation of evidence of studies,, researchers wrote, " Overall, these studies identify and support the use of nutraceuticals to provide symptomatic relief to patients with OA and to be used as an adjunct therapy for OA management".
Additionally, in the study to reaffirm the use of nutraceuticals for the treatment of Osteoarthritis, researchers launched an investigation to examine the efficacy of antioxidant and anti-inflammatory dietary supplements.
The searching of the literature on the databases of the MEDLINE (1996 through January 2009), results in a total of 16 clinical studies (11 randomized, placebo-controlled clinical trials, three crossover trials, one case-controlled study, and one open-label study) in addition to one meta-analysis and one review article satisfied the guideline and criteria.
Cat's claw used alone or combined with other herbal medicines were effective for the treatment of OA through antioxidant and anti-inflammatory properties.
Moreover, Dr, Hardin SR in the evaluation of the anti-OA effects of Cat's claw suggested that The mechanism of cat's claw appears to be as an inhibitor of TNF-alpha, an inflammatory cytokine produced in the chronic inflammation by the immune system and antioxidant.
However, further analysis of the nature and processes in osteoarthritis may facilitate and clarify the potential role of the cat's claw as a complementary therapy to assist in the reduction of pro-inflammatory mediators and effectors.
Taken all together, there is no doubt that herbal Cat's claw may be considered a functional herb for the prevention and adjunct therapy for the treatment of osteoarthritis without inducing any side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Current nutraceuticals in the management of osteoarthritis: a review by Akhtar N1, Haqqi TM. (PubMed)
(2) Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis by Rosenbaum CC1, O'Mathúna DP, Chavez M, Shields K.(PubMed)
(3) Cat's claw: an Amazonian vine decreases inflammation in osteoarthritis by Hardin SR.(PubMed)
(4) Genetics in Osteoarthritis by Mercedes Fernández-Moreno, Ignacio Rego, Vanessa Carreira-Garcia, and Francisco J Blanco. (PMC)
Tuesday, December 3, 2019
Herbal Chickweed Antimicrobial effects
Chickweed is a cool-season annual plant often eaten by chickens., genus S. media, belonging to the family Caryophyllaceae, native to Europe. The herb has been used in herbal medicine to treat skin conditions, indigestion, eczema, cough, rashes, etc. and as astringent, carminative, demulcent, diuretic, expectorant, laxative, refrigerant, vulnerary agent.
Chemical constituents(a)(b)
1. Igenin 6-C-beta-D-galactopyranosyl-8-C-alpha-L-arabinopyranoside
2. Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-galactopyranoside
3. Apigenin 6-C-beta-D-galactopyranosyl-8-C-beta-L-arabinopyranoside
4. Apigenin 6-C-beta-D-glucopyranosyl-8-C-beta-D-galactopyranoside
5. Apigenin 6, 8-di-C-alpha-L-arabinopyranoside
6. Alkaloidal glycoside
7. Glucodichotomine B
8. Neolignan glycosides
9. Dichotomosides A, B, C, and D
10. Phenylpropanoid glycoside
11. Dichotomoside E
12. Saponins
13. Mucilage
14. PABA
15. Coumarin,
16. Flavonoids (rutin)
17. Hydroxycoumarin
HSV-2 is a member of the herpes virus family and can be spread through contact with saliva,
Stellarmedin A, a novel antiviral protein purified from Stellaria media, showed to inhibit the proliferative and peroxidase activities of HSV-2 protein, according to the study by the Jiangsu Province and Chinese Academy of Sciences(1). Homologous defensins, Sm-AMP-D1 and Sm-AMP-D2, were isolated from seeds of common chickweed Stellaria media, according to the Russian Academy of Sciences, which showed a strong inhibitory activity against phytopathogenic fungi and oomycetes and may be a potent promising for engineering pathogen resistance in crops(2). α-hairpin, a novel antifungal peptide isolated from Stellaria media seeds, also exhibited high broad-spectrum activity against fungal phytopathogens(3).
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(a) [Studies on chemical constituents from stellaria media. I].[Article in Chinese] by Dong Q1, Huang Y, Qiao SY.(PubMed)
(b) Bioactive constituents from Chinese natural medicines. XIV. New glycosides of beta-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities by Morikawa T1, Sun B, Matsuda H, Wu LJ, Harima S, Yoshikawa M.(PubMed)
(1) Purification and characterization of a novel anti-HSV-2 protein with antiproliferative and peroxidase activities from Stellaria media by Shan Y1, Zheng Y, Guan F, Zhou J, Zhao H, Xia B, Feng X.(PubMed)
(2) Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds by Slavokhotova AA1, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA.(PubMed)
(3) Novel antifungal α-hairpinin peptide from Stellaria media seeds: structure, biosynthesis, gene structure and evolution by Slavokhotova AA1, Rogozhin EA, Musolyamov AK, Andreev YA, Oparin PB, Berkut AA, Vassilevski AA, Egorov TA, Grishin EV, Odintsova TI.(PubMed)
Chemical constituents(a)(b)
1. Igenin 6-C-beta-D-galactopyranosyl-8-C-alpha-L-arabinopyranoside
2. Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-galactopyranoside
3. Apigenin 6-C-beta-D-galactopyranosyl-8-C-beta-L-arabinopyranoside
4. Apigenin 6-C-beta-D-glucopyranosyl-8-C-beta-D-galactopyranoside
5. Apigenin 6, 8-di-C-alpha-L-arabinopyranoside
6. Alkaloidal glycoside
7. Glucodichotomine B
8. Neolignan glycosides
9. Dichotomosides A, B, C, and D
10. Phenylpropanoid glycoside
11. Dichotomoside E
12. Saponins
13. Mucilage
14. PABA
15. Coumarin,
16. Flavonoids (rutin)
17. Hydroxycoumarin
HSV-2 is a member of the herpes virus family and can be spread through contact with saliva,
Stellarmedin A, a novel antiviral protein purified from Stellaria media, showed to inhibit the proliferative and peroxidase activities of HSV-2 protein, according to the study by the Jiangsu Province and Chinese Academy of Sciences(1). Homologous defensins, Sm-AMP-D1 and Sm-AMP-D2, were isolated from seeds of common chickweed Stellaria media, according to the Russian Academy of Sciences, which showed a strong inhibitory activity against phytopathogenic fungi and oomycetes and may be a potent promising for engineering pathogen resistance in crops(2). α-hairpin, a novel antifungal peptide isolated from Stellaria media seeds, also exhibited high broad-spectrum activity against fungal phytopathogens(3).
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
References
(a) [Studies on chemical constituents from stellaria media. I].[Article in Chinese] by Dong Q1, Huang Y, Qiao SY.(PubMed)
(b) Bioactive constituents from Chinese natural medicines. XIV. New glycosides of beta-carboline-type alkaloid, neolignan, and phenylpropanoid from Stellaria dichotoma L. var. lanceolata and their antiallergic activities by Morikawa T1, Sun B, Matsuda H, Wu LJ, Harima S, Yoshikawa M.(PubMed)
(1) Purification and characterization of a novel anti-HSV-2 protein with antiproliferative and peroxidase activities from Stellaria media by Shan Y1, Zheng Y, Guan F, Zhou J, Zhao H, Xia B, Feng X.(PubMed)
(2) Isolation, molecular cloning and antimicrobial activity of novel defensins from common chickweed (Stellaria media L.) seeds by Slavokhotova AA1, Odintsova TI, Rogozhin EA, Musolyamov AK, Andreev YA, Grishin EV, Egorov TA.(PubMed)
(3) Novel antifungal α-hairpinin peptide from Stellaria media seeds: structure, biosynthesis, gene structure and evolution by Slavokhotova AA1, Rogozhin EA, Musolyamov AK, Andreev YA, Oparin PB, Berkut AA, Vassilevski AA, Egorov TA, Grishin EV, Odintsova TI.(PubMed)
Cinnamon - The Best Whole food Medicine for Reduced Risk of CVD
Recent study suggested that cinnamon expressed reduced risk of cardiovascular diseases through its antioxidant, chemopreventive, anti-inflammatory and immunomodulatory properties.
Heart disease kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease.
Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease. Here are some early indication of heart disease symptoms:
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The joint study lead by the North Khorasan University of Medical Sciences, also suggested the use of cinnamon for the prevention and treatment of CVD, probably due to its activities in inhibition of metabolic syndrome (MetS), the leading cause of heart diseases.
In support of the above suggestion, some recent studies reaffirm the importance of cinnamon as a spice and maybe a natural remedy to treat cardiovascular diseases.
Furthermore, the intake of cinnamon powder also exerted a beneficial effect on glycaemic control in animals and human models, affecting the progression of metabolic alterations in the early stage of cardiovascular events.
Dr. Deng said, "The hypoglycemic effects of cinnamon and .... were demonstrated in most of the trials with some exceptions" and " Future studies with more defined participants, standardized preparation and dose, and improved trial design and size are warranted".
Taken together, cinnamon may be beneficiary for the prevention, management, and treatment of cardiovascular diseases, but the quantity used of cinnamon should only be prescribed by an herbalist in the prevention of toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) The importance of selected spices in cardiovascular diseases by Kulczyński B1, Gramza-Michałowska A1.(PubMed)
(2) Cinnamon effects on metabolic syndrome: a review based on its mechanisms by Mollazadeh H1, Hosseinzadeh H2.(PubMed)
(3) Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities by Hamidpour R1, Hamidpour M2, Hamidpour S1, Shahlari M1.(PubMed)
(4) Effect of Cinnamon Tea on Postprandial Glucose Concentration by Bernardo MA1, Silva ML1, Santos E1, Moncada MM1, Brito J1, Proença L1, Singh J2, de Mesquita MF1.(PubMed)
Heart disease kills more than 2,000 Americans every day. Approximately 60 million Americans have heart disease.
Anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease. Here are some early indication of heart disease symptoms:
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the familyLauraceae, use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc.
The joint study lead by the North Khorasan University of Medical Sciences, also suggested the use of cinnamon for the prevention and treatment of CVD, probably due to its activities in inhibition of metabolic syndrome (MetS), the leading cause of heart diseases.
In support of the above suggestion, some recent studies reaffirm the importance of cinnamon as a spice and maybe a natural remedy to treat cardiovascular diseases.
Furthermore, the intake of cinnamon powder also exerted a beneficial effect on glycaemic control in animals and human models, affecting the progression of metabolic alterations in the early stage of cardiovascular events.
Dr. Deng said, "The hypoglycemic effects of cinnamon and .... were demonstrated in most of the trials with some exceptions" and " Future studies with more defined participants, standardized preparation and dose, and improved trial design and size are warranted".
Taken together, cinnamon may be beneficiary for the prevention, management, and treatment of cardiovascular diseases, but the quantity used of cinnamon should only be prescribed by an herbalist in the prevention of toxicity.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) The importance of selected spices in cardiovascular diseases by Kulczyński B1, Gramza-Michałowska A1.(PubMed)
(2) Cinnamon effects on metabolic syndrome: a review based on its mechanisms by Mollazadeh H1, Hosseinzadeh H2.(PubMed)
(3) Cinnamon from the selection of traditional applications to its novel effects on the inhibition of angiogenesis in cancer cells and prevention of Alzheimer's disease, and a series of functions such as antioxidant, anticholesterol, antidiabetes, antibacterial, antifungal, nematicidal, acaracidal, and repellent activities by Hamidpour R1, Hamidpour M2, Hamidpour S1, Shahlari M1.(PubMed)
(4) Effect of Cinnamon Tea on Postprandial Glucose Concentration by Bernardo MA1, Silva ML1, Santos E1, Moncada MM1, Brito J1, Proença L1, Singh J2, de Mesquita MF1.(PubMed)
Herbal Coltsfoot (Tussilago farfara) Inhibits Myelotoxicity
Myelotoxicity is a medical condition that causes the decrease of the production of cells responsible for immunity (leukocytes), carrying oxygen (erythrocytes), and/or for normal blood clotting (thrombocytes) due to bone marrow suppression.
Myeloperoxidase (MPO) is a peroxidase enzyme found most abundantly in white blood cells neutrophil granulocytes.
Myeloperoxidase (MPO) processes a critical role that protects our body against the invasion of microorganisms.
In cellular levels, myeloperoxidase (MPO) plays a critical role as a local mediator of tissue damage by stimulating the production of proinflammatory cytokines to protect the cell against foreign pathogens in the induction of acute phase of infection.
In other words, MPO deficiency induces the exaggerates of the inflammatory response that affects neutrophil functions including cytokine production in the acute phase of infection that can lead to chronic low-grade inflammatory disease.
MPO deficiency has been found in patients with diabetes mellitus, pregnancy, iron deficiency, renal transplantation, thrombotic diseases, lead poisoning, obstructive jaundice, disseminated cancers, hematologic disorders, and neoplasms.
However, genetic preposition may be the primary condition that causes the onset of PMO deficiency.
Dr. Roma Pahwa wrote, "Primary MPO deficiency is inherited as an autosomal recessive disorder and is generally present with varying degrees of severity and clinical features. A number of point germline mutations resulting in MPO deficiency have been detected in the primary form".
And, " Some of these mutations are associated with the defective posttranslational processing of the MPO precursor protein and others with pre-translational defects caused by mutations in the regulatory portion of the MPO gene".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of neutropenia, researchers examined the effects of Tussilago farfara L. polysaccharides on the immune response of the lung cancer animal model.
The study included selected C57Bl/6 mice with Lewis lung carcinoma treated by conventional cisplatin/paclitaxel polychemotherapy before administrating additional Tussilago farfara L. polysaccharides.
According to the tested analysis, Tussilago farfara L. polysaccharides not only reduced the side effects of cisplatin/paclitaxel polychemotherapy induced myelotoxicity associated with moderated neutropenia but also enhanced the efficacy of the chemo drugs activity.
Moreover, the stimulating effect of polysaccharides on the granulopoiesis lineage cells involved in myelopoiesis that differentiate into unipotent neutrophil progenitors in the lung tumor cells compared to those of CSF Neupogen.that increase production of white blood cells in the body.
In other words, polysaccharides exhibited immune-modulating activity against myelotoxicity induced by chemo drug side effects.
Taken altogether, coltsfoot may be considered a remedy for the improvement of myelopoiesis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modification of the Myelotoxic and Antitumor Effects of Polychemotherapy by Polysaccharides from Tussilago farfara L by Safonova EA1, Lopatina KA2, Razina TG2, Zueva EP2, Fedorova EP2, Gur'ev AM3, Belousov MV. (PubMed)
(2) Myeloperoxidase Deficiency by Roma Pahwa, and Ishwarlal Jialal. (NCBI)
Myeloperoxidase (MPO) is a peroxidase enzyme found most abundantly in white blood cells neutrophil granulocytes.
Myeloperoxidase (MPO) processes a critical role that protects our body against the invasion of microorganisms.
In cellular levels, myeloperoxidase (MPO) plays a critical role as a local mediator of tissue damage by stimulating the production of proinflammatory cytokines to protect the cell against foreign pathogens in the induction of acute phase of infection.
In other words, MPO deficiency induces the exaggerates of the inflammatory response that affects neutrophil functions including cytokine production in the acute phase of infection that can lead to chronic low-grade inflammatory disease.
MPO deficiency has been found in patients with diabetes mellitus, pregnancy, iron deficiency, renal transplantation, thrombotic diseases, lead poisoning, obstructive jaundice, disseminated cancers, hematologic disorders, and neoplasms.
However, genetic preposition may be the primary condition that causes the onset of PMO deficiency.
Dr. Roma Pahwa wrote, "Primary MPO deficiency is inherited as an autosomal recessive disorder and is generally present with varying degrees of severity and clinical features. A number of point germline mutations resulting in MPO deficiency have been detected in the primary form".
And, " Some of these mutations are associated with the defective posttranslational processing of the MPO precursor protein and others with pre-translational defects caused by mutations in the regulatory portion of the MPO gene".
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of neutropenia, researchers examined the effects of Tussilago farfara L. polysaccharides on the immune response of the lung cancer animal model.
The study included selected C57Bl/6 mice with Lewis lung carcinoma treated by conventional cisplatin/paclitaxel polychemotherapy before administrating additional Tussilago farfara L. polysaccharides.
According to the tested analysis, Tussilago farfara L. polysaccharides not only reduced the side effects of cisplatin/paclitaxel polychemotherapy induced myelotoxicity associated with moderated neutropenia but also enhanced the efficacy of the chemo drugs activity.
Moreover, the stimulating effect of polysaccharides on the granulopoiesis lineage cells involved in myelopoiesis that differentiate into unipotent neutrophil progenitors in the lung tumor cells compared to those of CSF Neupogen.that increase production of white blood cells in the body.
In other words, polysaccharides exhibited immune-modulating activity against myelotoxicity induced by chemo drug side effects.
Taken altogether, coltsfoot may be considered a remedy for the improvement of myelopoiesis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Modification of the Myelotoxic and Antitumor Effects of Polychemotherapy by Polysaccharides from Tussilago farfara L by Safonova EA1, Lopatina KA2, Razina TG2, Zueva EP2, Fedorova EP2, Gur'ev AM3, Belousov MV. (PubMed)
(2) Myeloperoxidase Deficiency by Roma Pahwa, and Ishwarlal Jialal. (NCBI)
Chaste tree berry, The Herbal Remedy Which Blocks the Onset of Premenstrual Syndrome (PMS)
Chaste tree berry, the queen of all herbs may have potency in the prevention and treatment of the premenstrual syndrome.
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
The exact causes of premenstrual syndrome are unknown. researchers also do not know why? women with the same health condition, some are more prone to the onset of PMS than others.
However, researchers do know that chemical changes in the brain during the menstrual cycle and period, leading to fluctuations of serotonin, a brain chemical (neurotransmitter) may play a crucial role in mood states and the imbalance of the levels of the hormone estrogen and progesterone could trigger PMS symptoms.
Truly, some researchers also suggested that insufficient amounts of serotonin produced a few days before menstruation may contribute to premenstrual symptoms such as depression, food cravings, and sleep problems.
Moreover, in the investigation of genes inherited from the parents and the risk of premenstrual syndrome, some researchers suggested that family history, ethnicity, and certain mutated gene could cause some women to succumb to PMS whereas others are left relatively unscathed.
Conventional medicine used to relieve pain in PMS, such as Nonsteroidal anti-inflammatory drugs and painkillers may be effective, but they induce certain side effects including stomach pain and heartburn, headaches and dizziness,.... and skin rash due to an allergic reaction.
In serious cases, the medicine cause stomach ulcers, liver and kidney condition,... and hypertension. If you are taking the medicine for a long-term, please make sure that you discuss the adverse effects with your doctor.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered as Queen herb in treating menstrual problems and discomforts, The herb also has been used in herbal medicine for thousands of year as an aphrodisiac agent.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed a significant reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) oral administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited the decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women study also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Additionally, according to Dr. Döll M, the extract of chaste tree berry decreased the levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress involved expression of symptoms of PMS.
Taking together, Chaste tree berry may be a safe herbal medicine for the prevention and treatment of PMS, by decreasing the levels of prolactin, and negative factors and enhancing the function of alleviating symptoms of the syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1. (PubMed)
(2) Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo-controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
The exact causes of premenstrual syndrome are unknown. researchers also do not know why? women with the same health condition, some are more prone to the onset of PMS than others.
However, researchers do know that chemical changes in the brain during the menstrual cycle and period, leading to fluctuations of serotonin, a brain chemical (neurotransmitter) may play a crucial role in mood states and the imbalance of the levels of the hormone estrogen and progesterone could trigger PMS symptoms.
Truly, some researchers also suggested that insufficient amounts of serotonin produced a few days before menstruation may contribute to premenstrual symptoms such as depression, food cravings, and sleep problems.
Moreover, in the investigation of genes inherited from the parents and the risk of premenstrual syndrome, some researchers suggested that family history, ethnicity, and certain mutated gene could cause some women to succumb to PMS whereas others are left relatively unscathed.
Conventional medicine used to relieve pain in PMS, such as Nonsteroidal anti-inflammatory drugs and painkillers may be effective, but they induce certain side effects including stomach pain and heartburn, headaches and dizziness,.... and skin rash due to an allergic reaction.
In serious cases, the medicine cause stomach ulcers, liver and kidney condition,... and hypertension. If you are taking the medicine for a long-term, please make sure that you discuss the adverse effects with your doctor.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered as Queen herb in treating menstrual problems and discomforts, The herb also has been used in herbal medicine for thousands of year as an aphrodisiac agent.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed a significant reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) oral administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited the decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women study also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Additionally, according to Dr. Döll M, the extract of chaste tree berry decreased the levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress involved expression of symptoms of PMS.
Taking together, Chaste tree berry may be a safe herbal medicine for the prevention and treatment of PMS, by decreasing the levels of prolactin, and negative factors and enhancing the function of alleviating symptoms of the syndrome.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1. (PubMed)
(2) Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo-controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
Monday, December 2, 2019
Chaste tree berry, The Whole Herb Medicine in Ameliorated Symptoms and Treatment of Premenstrual Syndrome
Chaste tree berry, the queen of all herbs may have potency in reduced symptoms and treatment of the premenstrual syndrome.
According to Dr. Döll M, the extract of chaste tree berry decreased levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress involved expression of symptoms of PMS.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered as Queen herb in treating menstrual problems and discomforts and used in herbal medicine for thousands of year as an aphrodisiac agent.
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed a significant reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) oral administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited the decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women study also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Taking together, Chaste tree berry may be a safe herbal medicine for the treatment of PMS, through decreased levels of prolactin, negative factors and ameliorated symptoms of the syndrome in many aspects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1.(PubMed)
(2) Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
According to Dr. Döll M, the extract of chaste tree berry decreased levels of prolactin serum during the first 3 weeks of the cycle of the premenstrual period, inducing stress involved expression of symptoms of PMS.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, considered as Queen herb in treating menstrual problems and discomforts and used in herbal medicine for thousands of year as an aphrodisiac agent.
Premenstrual syndrome is a faulty function of the ovaries related to the women's menstrual cycle, affecting women's physical and emotional state, and sometimes interfering with daily activities as a result of hormone fluctuation. The syndrome occurs one to two weeks before menstruation and then declines when the period starts.
In a prospective, double-blind, placebo-controlled, parallel-group, multi-center clinical trial in compared VAC BNO 1095 extract and placebo for up to three cycles, conducted by the Peking Union Medical College Hospital, group treated with extract of vitex agnus castus showed a significant reduced symptoms of PMS with mean total PMSD score decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) with no serious of side effects.
Furthermore, the extract of vitex agnus castus (VAC, BNO 1095) oral administrated in 67 patients enrolled and randomly assigned to receive one tablet of VAC or placebo once a day, exhibited the decreased premenstrual syndrome symptoms at the 3rd cycle, including symptoms of negative affect, water retention, food cravings, and pain, in the treatment group, compared to placebo group, especially in symptoms of water retention.
The moderate-to-severe premenstrual syndrome in Chinese women study also showed a significantly greater improvement of symptoms with intake of vitex agnus castus (VAC, BNO 1095)group than placebo, including the symptom of insomnia.
Taking together, Chaste tree berry may be a safe herbal medicine for the treatment of PMS, through decreased levels of prolactin, negative factors and ameliorated symptoms of the syndrome in many aspects.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) [The premenstrual syndrome: effectiveness of Vitex agnus castus].[Article in German]by Döll M1.(PubMed)
(2) Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China by He Z1, Chen R, Zhou Y, Geng L, Zhang Z, Chen S, Yao Y, Lu J, Lin S.(PubMed)
(3) Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus(BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Wang X.(PubMed)
(4) Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women by Ma L1, Lin S, Chen R, Zhang Y, Chen F, Wang X.(PubMed)
Catnip, the Natural Dopamine for Penile Erection and Male Sexual Desire
Many researchers have raised questions of their's quality and effectiveness, depending too much on geographic differences, time of grown and harvest, etc.. I do believe, these questions can only be answered by an experienced herbalists.
Dopamine, a neurotransmitter plays an important role in the brain of the human body, including sexual behavior. Besides in the regulation of cognitive, integrative and reward processes, the organic chemical of catecholamine and phenethylamine also can trigger penile erection and control of sexual function by acting on oxytocinergic neurons.
Dr. Baskerville TA said," dopamine demonstrates the potential existence of an interaction between central dopamine and hormone in controlling sexual reproduction during penile erection
In fact, the effect of a pro-erectile dose of apomorphine, a mixed dopamine receptor agonist, showed stimulation of dopamine receptors, induced the release of oxytocin in the brain to mediate and reinforcing effects of sexual activity in regulating the sexual behavior (e.g., penile erection) with those controlling sexual motivation and sexual arousal.
Catnip may be the next generation of herbal medicine used as dopamine to increase penile erection and improve male sexual behavior.
Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, used in herbal medicine as insect repellent and to treat digestive disorders, children restlessness and nervousness, fevers, colds and flu, skin irritations stimulate sweating, promote menstruation, etc.
According to the Paulista University, male rats of the NC group increased penile erection. facilitate sexual behavior and a decreased in general activity involved dopaminergic systems.
Several studies suggested that dopamine is a neurotransmitter plays an important role in regulating and controlling penile erection and sexual behavior, but the use of herbal medicine should only be prescribed by herbalist to prevent depression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats by Bernardi MM1, Kirsten TB, Lago JH, Giovani TM, Massoco Cde O.(PubMed)
(2) Dopamine and male sexual function by Giuliano F1, Allard J.(PubMed)
(3) Dopamine-oxytocin interactions in penile erection by Baskerville TA1, Allard J, Wayman C, Douglas AJ.(PubMed)
Dopamine, a neurotransmitter plays an important role in the brain of the human body, including sexual behavior. Besides in the regulation of cognitive, integrative and reward processes, the organic chemical of catecholamine and phenethylamine also can trigger penile erection and control of sexual function by acting on oxytocinergic neurons.
Dr. Baskerville TA said," dopamine demonstrates the potential existence of an interaction between central dopamine and hormone in controlling sexual reproduction during penile erection
In fact, the effect of a pro-erectile dose of apomorphine, a mixed dopamine receptor agonist, showed stimulation of dopamine receptors, induced the release of oxytocin in the brain to mediate and reinforcing effects of sexual activity in regulating the sexual behavior (e.g., penile erection) with those controlling sexual motivation and sexual arousal.
Catnip may be the next generation of herbal medicine used as dopamine to increase penile erection and improve male sexual behavior.
Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia, used in herbal medicine as insect repellent and to treat digestive disorders, children restlessness and nervousness, fevers, colds and flu, skin irritations stimulate sweating, promote menstruation, etc.
According to the Paulista University, male rats of the NC group increased penile erection. facilitate sexual behavior and a decreased in general activity involved dopaminergic systems.
Several studies suggested that dopamine is a neurotransmitter plays an important role in regulating and controlling penile erection and sexual behavior, but the use of herbal medicine should only be prescribed by herbalist to prevent depression.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats by Bernardi MM1, Kirsten TB, Lago JH, Giovani TM, Massoco Cde O.(PubMed)
(2) Dopamine and male sexual function by Giuliano F1, Allard J.(PubMed)
(3) Dopamine-oxytocin interactions in penile erection by Baskerville TA1, Allard J, Wayman C, Douglas AJ.(PubMed)
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