Medical Advisor Journals

Monday, May 30, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Herbal Bai Hua She She Cao (herba hedyotidis Diffusae)

Bai Hua She She Cao also known as spreading hedyotis, the bitter, sweet and cold herb has been used in TCM as anti-bacteria, anti-inflammation, anti-tumor, anti-virus medicine and to enhance immune system, treat toxic sores, ulcerations, swellings, snake bites, sore throat, bronchitis, tonsillitis, and hemorrhoids, etc., as it enhances Clears Heat, Drains Dampness, Expels toxins, Resolves abscesses by enhancing the functions of liver, stomach, large intestine channels.

Ingredients
1. E-6-0-P(E-6-0-p-coumaroyl scandoside methyl ester
2. P-coumaric acid
3. Oleanolic acid
4. Trans p-coumaric acid
5. Ursolic acid
6. Sitosterol
7. β-sitosterol
8. Flavone
9. β-sitosterol-D-glucose
10. Hentriacontane
11. Etc.

Health Benefits
1. Anti Cancer
Hedyotis Diffusa Willd (Bai Hia She She Cao) extract had inhibited tumor angiogenesis by promoting cancer cell apoptosis via activation of the mitochondrial-dependent pathway with little side effects, according to the study of “Effect of Hedyotis Diffusa Willd extract on tumor angiogenesis” by Lin J, Wei L, Xu W, Hong Z, Liu X, Peng J., posted in PubMed(1).

2. Leukemia
Isolated splenocytes from HDW extract has demonstrated an increase of T- and B-cell proliferation in treating leukemic mice, in vivo, according to the study of “Extract of Hedyotis diffusa Willd influences murine leukemia WEHI-3 cells in vivo as well as promoting T- and B-cell proliferation in leukemic mice” by Lin CC, Kuo CL, Lee MH, Hsu SC, Huang AC, Tang NY, Lin JP, Yang JS, Lu CC, Chiang JH, Chueh FS, Chung JG., posted in PubMed(2).

3. Breast Cancer
Methylanthraquinone from Hedyotis diffusa WILLD have induced MCF-7 cells (a breast cancer cell line)apoptosis via Ca(2+)/calpain/caspase-4 pathway, according to the study of
“Methylanthraquinone from Hedyotis diffusa WILLD induces Ca(2+)-mediated apoptosis in human breast cancer cells” by Liu Z, Liu M, Liu M, Li J., posted in PubMed(3).

4. Colon cancer
Hedyotis Diffusa Willd extract has exerted the activity of inducing apoptosis of colon cancer cell line via activation of the mitochondrion-dependent pathway, according to the study of “Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells” by Lin J, Chen Y, Wei L, Chen X, Xu W, Hong Z, Sferra TJ, Peng J., posted in PubMed(4).

5. Anti colon, liver and lung cancer
Hedyotis diffusa Willd. (Rubiaceae) has demonstrated the activity of inhibition of cell growth and induction of cell apoptosis in COLO 205 (colon cancer), Hep 3B (hepatocellular carcinoma) and H460 (lung cancer) cell lines., due to its chemical compound ursolic aci, according to the study of “Clarification of the phenotypic characteristics and anti-tumor activity of Hedyotis diffusa” by Lee HZ, Bau DT, Kuo CL, Tsai RY, Chen YC, Chang YH., posted in PubMed(5).

6. Etc.

Side effects
1. Bai Hua She She Cao may cause allergic reactions of discomfort and rash and itches and sever of breathing difficulty to certain people.
2. Do not use if you are pregnant or breast feeding without approval of your doctor or related field of specialist
3. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21887465
(2) http://www.ncbi.nlm.nih.gov/pubmed/21709007
(3) http://www.ncbi.nlm.nih.gov/pubmed/19686834
(4) http://www.ncbi.nlm.nih.gov/pubmed/20878081
(5) http://www.ncbi.nlm.nih.gov/pubmed/21213409

The Best smoothie of Green Tea, Orange and Peanut for Prevention and Treatment of Cervical myomas

Kyle J. Norton(Scholar, Master of Nutrient, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of cervical myomas
Yield: 2 servings (about 8 ounces each)
1/2 cup peanut
1 orange
1 cup green tea drink (Make from 4 grams of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed

3. Serve immediately

The finding of a natural source for reduced risk and treatment of cervical polyps to replace the conventional medicine has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Cervical myomas (3%-9% of all leiomyomas) are benign tumor arising from the lower uterine segment. The myoma may bleed, become infected, interfere with urinating, or cause pain during sexual intercourse. Surgery may be the best option but it also induced blood loss, and distortion of the anatomy of the vital neighboring structures in the pelvic cavity, if myomas are closer to other organs such as the bladder, ureter, and rectum(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. Its Epigallocatechin gallate (EGCG), the major catechin in green tea has shown to to inhibit key pathways of tumor growth(2)

According to the Oncology and Radiobiology, NAS of Ukraine, polyphenol extracts from green tea, red wine lees and/or lemon peel alone used conjuction with antitumor drugs effectively ameliorated the growth of different transplanted tumors in animal model(3).

Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in peanuts, also expressed strongly anti tumors effect in experimental animal(3). According to the The University of Tokyo, resveratrol (3, 5, 4'-trihydroxystilbene) is a phytoalexin contained in a variety of plants exhibited anti tuome effect through suppressed cell proliferation, induced apoptosis and suppressed the metastasis and cell invasion through suppress cell proliferation, induce apoptosis and suppress the metastasis and cell invasion through regulating cellular mechanisms(4), including cell cycle arrest and apoptosis in intestinal smooth muscle cells.(5).

Vitamin C, a water soluble vitamin, found abundantly in orange manifested anti tumor activities through expression of strongest activator of phagocytosis and antibody formation when used conjunction with glucan, resveratrol(6).

According to the Seoul National University College of Medicine, vitamin C also increases the susceptibility of tumor cells to anti-Fas Abs and the expression of Fas (CD95) and MHC class I on tumor cells, in dose-depend manner(7).

The effectiveness of Green Tea, Orange and Peanut may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of Cervical myomas with little or no adverse effects.

Women who are at increased risk of . Otherwise, intake of Cervical myomas due to family history,..... should drink at least 1 serving daily. Women with Cervical myomas should drink as much as they can, depending to digestive toerlation.

Life style and dietary patter change are recommended.

All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References

(1) Handling cervical myomas by Patel P1, Banker M, Munshi S, Bhalla A.(PubMed)

(2) Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate by Khan N1, Afaq F, Saleem M, Ahmad N, Mukhtar H.(PubMed)

(3) Green tea, red wine and lemon extracts reduce experimental tumor growth and cancer drug toxicity by Zaletok SP1, Gulua L2, Wicker L3, Shlyakhovenko VA1, Gogol S1, Orlovsky O1, Karnaushenko OV1, Verbinenko A1, Milinevska V1, Samoylenko O1, Todor I1,Turmanidze T2.(PubMed)

(4) Anti-tumor effects and cellular mechanisms of resveratrol by Han G1, Xia J, Gao J, Inagaki Y, Tang W, Kokudo N.(PubMed)

(5) Resveratrol causes cell cycle arrest, decreased collagen synthesis, and apoptosis in rat intestinal smooth muscle cells by Garcia P1, Schmiedlin-Ren P, Mathias JS, Tang H, Christman GM, Zimmermann EM.(PubMed)

(6) Combination of glucan, resveratrol and vitamin C demonstrates strong anti-tumor potential by Vetvicka V1, Vetvickova J.(PubMed)

(7) The Anti-tumor Activity of Vitamin C via the Increase of Fas (CD95) and MHC I Expression on Human Stomach Cancer Cell Line, SNU1 by Yu Y1, Bae S, Kim H, Kim Y, Chu NB, Chu NK, Kang JS, Lee WJ.(PubMed)

Most Common Diseases of 50plus: Diabetes Treatment In Herbal medicine perspective

Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol.

Treatments

B. In herbal medicine perspective
The below herbs may have a potential to treat and cure diabetes, according to studies.
1. Cinnamon
Cinnamon is a spice derived from the inner bark of tree, native to South East Asia, of over 300 species of the genus Cinnamomum, belonging to the family Lauraceae.. The herb has been use in herbal and traditional medicine as anti-fungal and bacteria level to improve reproductive organ, prevent flatulence and intestinal cramping, treat indigestion, diarrhea, bad breath, headache, migraine, etc. Cinnamon contains chemicals that tell the cells in your pancreas to release more insulin into the bloodstream. In the investigation of the clinical potential of aqueous extract of cinnamon and it potential effects in diabetes found that high in type A polyphenols, have also demonstrated improvements in fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome, according to”Chromium and polyphenols from cinnamon improve insulin sensitivity” by Anderson RA(96). In other study of investigation of Myristicin (1-allyl-5-methoxy-3,4-methylenedioxybenzene) is an active aromatic compound found in nutmeg (the seed of Myristica fragrans), carrot, basil,cinnamon, and parsley and it anti-inflammatory effects found that Myristicin significantly inhibited the production of calcium, nitric oxide (NO),interleukin (IL)-6, IL-10, interferon inducible protein-10, monocyte chemotactic protein(MCP)-1, MCP-3, granulocyte-macrophage colony-stimulating factor, macrophage inflammatory protein (MIP)-1α, MIP-1β, and leukemia inhibitory factor in dsRNA[polyinosinic-polycytidylic acid]-induced RAW 264.7 cells (P < 0.05), according to the study of “Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid” by Lee JY, Park W. (97).

2. Milk thistle
Milk Thistle is a flowering plant, in the genus Silybum Adans, belonging to the family Asteraceae, native to the Mediterranean. The herb has been used in traditional medicine in treating liver, kidney, gall bladder problems, etc. Milk thistle contains sylimarin that can inhibit kidney damage related to diabetes. In the demonstration of Silybum marianum seed extract (silymarin) and its antioxidant properties on the glycemic profile in diabetic patients found that a significant decrease in HbA(1)c, FBS, total cholesterol, LDL, triglyceride SGOT and SGPT levels in silymarin treated patients compared with placebo as well as with values at the beginning of the study in each group. In conclusion, silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile, according to “The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial” by Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, Radjabipour B, Toliat T, Raza M(98).

3. Bilberry
Bilberry is a species of low-growing shrubs in the genus Vaccinium, belonging to the family Ericaceae, native to Northern Europe. it has been used as foods and herbs in traditional medicine in treating acute and chronic diarrhea, gastritis, gastric ulcer and duodenal ulcer, enterocolitis, ulcerative colitis, anemia, cystitis, kidney disease and psoriasis, diabetes, etc. Bilberry contains biotin that can reduce blood glucose levels. Bilberry leaves (Vaccinium myrtillus L.) has been used in traditional medicine in treating diabetes over thousand of year. The experiment of effect of dietary bilberry extract (BBE) on hyperglycemia and insulin sensitivity in type 2 diabetic mice, see significant activity of the extract in improving hyperglycemia and insulin sensitivity in type 2 diabetes in the study of “Dietary anthocyanin-rich bilberry extract ameliorates hyperglycemia and insulin sensitivity via activation of AMP-activated protein kinase in diabetic mice” by Takikawa M, Inoue S, Horio F, Tsuda T.(99).
In other study of 110 female volunteers were recruited, and they followed four different berry diets (BB, SB, SB phenolic extract (SBe) and SB oil (SBo)) in a randomized order for 33-35 days, conducted by University of Turku, researchers found that Based on the results, it can be stated that different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases(100).

4. Dandelion
Dandelion is a herbaceous perennial plant, genus Taraxacum, beloning to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure and heart weakness, chronic joint, skin diseases, etc,.
In the research of aqueous extracts and their effect on alpha-glucosidase inhibitory activity found that Urtica dioica, Taraxacum officinale, Viscum album, and Myrtus communis with alpha-glucosidase inhibitor activity was conducted to identify a prophylactic effect for diabetes in vitro. All plants showed differing potent alpha-glucosidase inhibitory activity, according to the study of “Inhibition of alpha-glucosidase by aqueous extracts of some potent antidiabetic medicinal herbs’ by Onal S, Timur S, Okutucu B, Zihnioğlu F(101).
Other study in the analyzing luteolin and chicoric acid, two abundant constituents of the common dandelion and their anti-inflammatory effects found that luteolin plays a central role in ameliorating LPS-induced inflammatory cascades via inactivation of the NF-κB and Akt pathways, and that chicoric acid strengthens the anti-inflammatory activity of luteolin through NF-κB attenuation, according to the study of “Luteolin and chicoric acid synergistically inhibited inflammatory responses via inactivation of PI3K-Akt pathway and impairment of NF-κB translocation in LPS stimulated RAW 264.7 cells” by Park CM, Jin KS, Lee YW, Song YS(102).

5. Cayenne
Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to sub-tropical and tropical regions. It has been used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises and neuralgia, etc,. Dietary capsaicin has markedly decreased fasting glucose/insulin and triglyceride levels in the plasma and/or liver, as well as expression of inflammatory adipocytokine genes and increased in adipose tissue and/or plasma, accompanied by increased activation of hepatic AMP-activated protein kinase, a marker of fatty acid oxidation., according to the study of “Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice” by Kang JH, Tsuyoshi G, Le Ngoc H, Kim HM, Tu TH, Noh HJ, Kim CS, Choe SY, Kawada T, Yoo H, Yu R(103).

6. Ginkgo biloba
Ginkgo biloba is oldest living tree species, genus Ginkgo, belonging to the family Gink-
goaceae, native to China, from temperate zone to subtropical zone and some parts of north America. It Has been used in traditional herbal medicine in treating impotence, memory loss,respiratory diseases, circulatory disorders and deafness as well as preventing drunkenness, and bedwetting.
Ginkgo biloba extract by an NIDDM subject may increase the hepatic metabolic clearance rate of not only insulin but also the hypoglycemic agents. The result is reduced insulin-mediated glucose metabolism and elevated blood glucose, according to the study by The Department of Clinical Laboratory Sciences, School of Allied Health Sciences-MSC 6246(104).

General Health: Candida Albicans: Some life threatening implications of candida overgrowth

1. Toxic shock syndrome(TSS)
Candida overgrowth can cause toxic shock syndrome (TSS)(157), a potentially fatal illness by producing toxins to suppress the immune system(158)(159), leading to infection cause of high fever, accompanied by confusion, extreme fatigue and weakness, headache, severe diarrhea, sore throat, vomiting, widespread red rash, coma(161), and multiple organ failure(160).

2. Scalded skin syndrome (SSS)
Scalded skin syndrome is defined as a condition of skin infection caused of damage to the skin with marked shedding due to toxins(162) released by candida in suppressing the immune system(162). Depending its severity, it can causes bloodstream infection(163) and electrolyte imbalance, involved in regulate myocardial and neurological function(164), fluid balance(165), oxygen delivery, etc., resulting in high morbidity and mortality(166).

3. Candida and chronic diseases
a. Irritable Bowel Syndrome (IBS)(167)(168)
As the condition worsen, candida takes advantage of weakness immune system and imbalances in the digestive system, allowing fungus to overrun the digestive tracts(169), leading to gases which irritate the intestinal and stomach linings(171) cause of pain(170)(172).

b. Chronic Sinusitis(173)
As candida growth occurs in the sinus cavities(173), it causes fungal serious infections, with symptoms of nasal congestion, facial pain, pressure, congestion, or fullness, reduced or absent sense of smell. Both chronic and acute fungal sinusitis require immediate treatment(174).

c. Fibromyalgia
Fibromyalgia syndrome is a chronic condition that causes intense pain in various places around the body, including muscles, connective tissues and joints, as well as a host of other symptoms, as a result of production of mycotoxins by overgrowth candida(175), causing autoimmune diseases(143)(144)(136) by triggering inflammation in the intestinal tract(151). Fibromyalgia syndrome affects more than 6 million people in the United States.

d. Chronic Fatigue Syndrome
Chronic fatigue syndrome (CFS) is defined as a health condition of persistent fatigue unrelated to exertion, it interferes with the patient daily activity, causing trouble staying on top of their responsibilities at home and on the job, etc.(176) due to production of mycotoxins by overgrowth candida(177)(178), triggering inflammation(179) in the intestinal tract. Symptoms of chronic fatigue syndrome include headache, tender lymph nodes, fatigue, weakness, muscle, joint aches, inability to concentrate,(180) etc.

e. Thrush
Thrush is defined as condition of infection of the mouth caused by over growth candida fungus(181)(182).

f. Eczema, or Atopic Dermatitis
Eczema is a general term for many types of skin inflammation (dermatitis). The most common form of eczema is atopic dermatitis in some case caused by over growth of candida(183)(184) as a result of immune suppressive factors(185).

g. Etc.

Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

References
(1) Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance by Krcmery V1, Barnes AJ.(PubMed)
(2) Pathogenicity and drug resistance in Candida albicans and other yeast species. A review by Mishra NN1, Prasad T, Sharma N, Payasi A, Prasad R, Gupta DK, Singh R.(PubMed)
(3) Multidrug resistance in yeast Candida by Prasad R1, Kapoor K.(PubMerd)
(4) New evidence that Candida albicans possesses additional ATP-binding cassette MDR-like genes: implications for antifungal azole resistance. by Walsh TJ1, Kasai M, Francesconi A, Landsman D, Chanock SJ.(PubMed)
(5) Mechanisms of resistance to azole antifungal agents in Candida albicansisolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
(7) The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms by Ibrahim NH1, Melake NA2, Somily AM3, Zakaria AS4, Baddour MM5, Mahmoud AZ6(PubMed)
(8) Antifungal drug resistance in pathogenic fungi. by Vanden Bossche H1, Dromer F, Improvisi I, Lozano-Chiu M, Rex JH, Sanglard D.(PubMed)
(9) The genetic basis of fluconazole resistance development in Candida albicansby Morschhäuser J1.(PubMed)
(10) A proteomic approach to understanding the development of multidrug-resistantCandida albicans strains by Kusch H1, Biswas K, Schwanfelder S, Engelmann S, Rogers PD, Hecker M, Morschhäuser J.(PubMed
(157)Effect of strain of Staphylococcus aureus on synergism with Candidaalbicans resulting in mouse mortality and morbidity. Carlson E.(PubMed)
(158)Lesson of the month 2: toxic shock syndrome.
Shalaby T1, Anandappa S2, Pocock NJ2, Keough A2, Turner A2.(PubMed)
(159)Staphylococcal toxic shock syndrome: superantigen-mediated enhancement of endotoxin shock and adaptive immune suppression. Kulhankova K1, King J, Salgado-Pabón W.(PubMed)
(160) Toxic Shock Syndrome, C health
(161)Group A streptococcal toxic shock syndrome with extremely aggressive course in the third trimester. Sugiyama T1, Kobayashi T, Nagao K, Hatada T, Wada H, Sagawa N.(PubMed).
(162) Scalded skin syndrome, the university of Maryland medical center
(163)Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study. Kett DH1, Azoulay E, Echeverria PM, Vincent JL; Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators.(PubMed)
(164) [Infectious and metabolic nervous system complications of systemic cancer].[Article in Spanish]Ortiz N1.(PubMed)
(165) [Voriconazole compromises renal function in an elderly CDK patient withCandida albicans infection].[Article in Italian] Anastasio P1,.(PubMed)
(166)Endogenous thrombospondin-1 regulates leukocyte recr Marcarelli F, Bilancio G, Mele AA, De Santo NGuitment and activation and accelerates death from systemic candidiasis. Martin-Manso G1, Navarathna DH, Galli S, Soto-Pantoja DR, Kuznetsova SA, Tsokos M, Roberts DD.(PubMed)
(167) [Life-threatening complications of Crohn's disease and ulcerative colitis: a systematic analysis of admissions to an ICU during 18 years]. [Article in German] Huber W1, Herrmann G, Schuster T, Phillip V, Saugel B, Schultheiss C, Hoellthaler J, Gaa J, Hartel M, Schmid RM, Reindl W.(PubMed)
(168)The role of Candida albicans in the pathogenesis of food-intolerant irritable bowel syndrome. Shepherd C.(PubMed)
(169) Yeasts in the gut: from commensals to infectious agents. Schulze J1, Sonnenborn U.(PubMed)
(170) Treatment of abdominal pain in irritable bowel syndrome. Vanuytsel T1, Tack JF, Boeckxstaens GE.(PubMed)
(171) Current gut-directed therapies for irritable bowel syndrome. Chang HY1, Kelly EC, Lembo AJ.(PubMed)
(172) Abdominal pain in Irritable Bowel Syndrome: a review of putative psychological, neural and neuro-immune mechanisms.Elsenbruch S1.(PubMed)
(173) [Changes of etiology of chronic sinusitis].[Article in Chinese] Deng Q1, Peng P.(PubMed)
(174)Invasive fungal sinusitis of the sphenoid sinus. Lee DH1, Yoon TM1, Lee JK1, Joo YE2, Park KH3, Lim SC1.(PubMed)
(175) Occurrence of killer yeasts in isolates of clinical origin. Robledo-Leal E1, Villarreal-Treviño L, González GM.(PubMed)
(176)Experiences of daily activity in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) and their implications for rehabilitation programmes.Pemberton S1, Cox DL.(PubMed)
(177) Chronic illness associated with mold and mycotoxins: is naso-sinus fungal biofilm the culprit? Brewer JH1, Thrasher JD, Hooper D.(PubMed)
(178) Detection of mycotoxins in patients with chronic fatigue syndrome.Brewer JH1, Thrasher JD, Straus DC, Madison RA, Hooper D.(PubMed)
(179) Exposure to zearalenone mycotoxin alters in vitro porcine intestinal epithelial cells by differential gene expression.Taranu I1, Braicu C2, Marin DE3, Pistol GC3, Motiu M3, Balacescu L2, Beridan Neagoe I2, Burlacu R4.(PubMed)
(180)Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome.
Forsyth LM1, Preuss HG, MacDowell AL, Chiazze L Jr, Birkmayer GD, Bellanti JA.(PubMed)
(181) Identification of Candida albicans genes induced during thrush offers insight into pathogenesis. Cheng S1, Clancy CJ, Checkley MA, Handfield M, Hillman JD, Progulske-Fox A, Lewin AS, Fidel PL, Nguyen MH.(PubMed)
(182) Is endometrial infection with Candida albicans a cause of recurrent vaginalthrush?Smith JR1, Wells C, Jolly M, Shah P, Savage M, Reginald P, Kitchen VS.(PubMed)
(183) Candida albicans-specific lymphoproliferative and cytokine (IL-4 and IFN-gamma) responses in atopic eczema dermatitis syndrome. Evidence of CD4/CD8 and CD3/CD16+CD56 ratio elevations in vitro. Kosonen J1, Luhtala M, Viander M, Kalimo K, Terho EO, Savolainen J.(PubMed)
(184) Candida albicans mannan- and protein-induced humoral, cellular and cytokine responses in atopic dermatitis patients. Savolainen J1, Kosonen J, Lintu P, Viander M, Pène J, Kalimo K, Terho EO, Bousquet J.(PubMed)
(185) Guidelines for treatment of atopic eczema (atopic dermatitis) Part II.
Ring J1, Alomar A, Bieber T, Deleuran M, Fink-Wagner A, Gelmetti C, Gieler U, Lipozencic J, Luger T, Oranje AP, Schäfer T, Schwennesen T, Seidenari S, Simon D, Ständer S, Stingl G, Szalai S, Szepietowski JC, Taïeb A, Werfel T, Wollenberg A, Darsow U; European Dermatology Forum; European Academy of Dermatology and Venereology; European Task Force on Atopic Dermatitis; European Federation of Allergy; European Society of Pediatric Dermatology; Global Allergy and Asthma European Network.(PubMed)

Most common Diseases of 50plus: The Obesity' Research and Studies of Monounsaturated fatty acids and obese NIDDM patients

The Smoothie of Orange, Spinach and Grape Juice for Prevention and Treatment of Breast Hematoma

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The curable smoothie for reduced risk and treatment of Breast hematoma
1 cup of organic orange
1/2 spinach
1 cup organic grape juice

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding of a natural source for reduced risk and treatment of Breast hematoma has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(such as Ginger, Alfalfa Sprout and Orange) for reduced risk and treatment of Breast hematoma.

Breast hematoma is a collection of blood due to bleeding within the breast. According to the Penn State Milton S. Hershey Medical Center, "The probability of development of a non-clinically significant hematoma was 21.6% for patients taking antithrombotics and 13.0% for those not taking antithrombotics"(1).

Vitamin K, found abundantly in spinach has exerted its coagulation effects in reduced risk of (subdural) hematoma, in a randomized trials identified from the Cochrane Central Register of Controlled Trials(2).

The Fuwai Hospital joint study also suggested, the favorite uninterrupted vitamin K antagonists (VKAs), in comparison to anticoagulation in catheter ablation (CA) of atrial fibrillation (AF) in occurrence of stroke or transient ischemic attacks and major bleeding in test subjects(3).

Dr. Levi M said, "Bleeding is the most important adverse effect of antithrombotic treatment and may be a major cause of morbidity, longstanding debilitation, and even mortality....... can be neutralized by the administration of vitamin K or prothrombin complex concentrates"(4).

Vitamin C, a water soluble vitamin found in orange may also benefit women with breast hematoma by preventing the breaking off capillaries, the small vessels in the breast inducing bleeding(5).

According to the University Clinic Muenster, Vitamin C was shown to be cerebroprotective in several animal models of stroke, through the expression and transport activity of SVCT2, :key proteins for vitamin C uptake. in brain capillary endothelial cells after transhwaient ischemia in mice(6).

Resveratrol, a phytochemical in the class of Stilbenoids, found abundantly in grape may also reduced risk of complications caused by severe hemorrhagic injury, including the Lung(8), intestines(9), cystitis(10),.....through both pro and anti-inflammatory pathways(7).

The effectiveness of Orange, Spinach and Grape Juice may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk and treatment of Breast hematoma with little or no adverse effects.

Women who are at increased risk of Breast hematoma due to family history, aging,.....may drink at least one serving daily and women with Breast hematoma may drink as much as they can, depending to the digestive toleration.
Life style and dietary patter change are recommended.

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References
(1) Hematoma formation during breast core needle biopsy in women taking antithrombotic therapy by Chetlen AL1, Kasales C, Mack J, Schetter S, Zhu J.(PubMed)
(2) Vitamin K antagonists and risk of subdural hematoma: meta-analysis of randomized clinical trials by Connolly BJ1, Pearce LA1, Hart RG2.(PubMed)
(3) Meta-Analysis of Efficacy and Safety of New Oral Anticoagulants Compared With UninterruptedVitamin K Antagonists in Patients Undergoing Catheter Ablation for Atrial Fibrillation. by Wu S1, Yang YM2, Zhu J1, Wan HB1, Wang J1, Zhang H1, Shao XH1.(PubMed)
(4) Emergency Reversal Strategies for Anticoagulation and Platelet Disorders by Levi M1.(PubMed)
(5) High-dose vitamin C treatment reduces capillary leakage after burn plasma transfer in rats by Kremer T1, Harenberg P, Hernekamp F, Riedel K, Gebhardt MM, Germann G, Heitmann C, Walther A.(PubMed)
(6) Sodium-dependent vitamin C transporter 2 (SVCT2) expression and activity in brain capillaryendothelial cells after transient ischemia in mice by Gess B1, Sevimli S, Strecker JK, Young P, Schäbitz WR.(PubMed)
(7) Alteration of cytokine profile following hemorrhagic shock by Lu S1, Aguilar A1, Subramani K1, Poulose N1, Ayub A1, Raju R2.(PubMed)
(8) Dihydro-Resveratrol Ameliorates Lung Injury in Rats with Cerulein-Induced Acute Pancreatitis by Lin ZS1,2, Ku CF1, Guan YF1, Xiao HT1, Shi XK1, Wang HQ2, Bian ZX1, Tsang SW1,3, Zhang HJ1.(PubMed)
(9) Effects of resveratrol on methotrexate-induced intestinal injury by Yulug E, Turedi S, Alver A, Turedi S, Kahraman C.(PubMed)
(10) Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna by Keles I1, Bozkurt MF, Cemek M, Karalar M, Hazini A, Alpdagtas S, Keles H, Yildiz T, Ceylan C, Buyukokuroglu ME.(PubMed)

Most common Diseases of 50plus: Obesity and Obesity's complication of Inguinal Hernia

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

Inguinal hernia is defined as a condition of forming of a sac by the lining of the abdominal cavity (peritoneum) as a result of protrusion of abdominal-cavity contents through the inguinal canal. According to the statistics, the risk of Inguinal Hernia is higher in male, accounted for 27% and lower in female accounted for only 3% of the disease. If left untreated, it may be fatal to the host if the disease progress rapidly.

How Obesity associates with Inguinal Hernia
1, In the study of "Effect of body mass index on groin hernia surgery" by Rosemar A, Angerås U, Rosengren A, Nordin P., posted in PubMed, researchers filed the result that Of the 49,094 patients, 3.5% had a BMI <20 kg/m2 and 5.2% were obese. Altogether, women constituted only 7.7% of the studied group, but among patients with BMI <20 kg/m2 that had surgical procedures for femoralhernia, 81.4% were women. The relation between BMI and postoperative complications was U-shaped and after adjustment for age, gender, and emergency procedure, patients with BMI <20 and >25 had a significant increased risk when compared with patients with BMI from 20 to 25. Reoperation for recurrence of groinhernia has an increased hazard ratio of 1.20 (95% confidence interval, 1.00-1.40) in overweight, which was particularly evident after open suture and preperitoneal mesh techniques.

2. According to the abstract of the study of "Risk factors for inguinal herniaamong adults in the US population" by Ruhl CE, Everhart JE., posted inPubMed, researchers stated that among men in multivariate analysis, a higher incidence (p < 0.05) of inguinal hernia was associated with an age of 40-59 years (hazard ratio (HR) = 2.2, 95% confidence interval (CI): 1.7, 2.8), an age of 60-74 years (HR = 2.8, 95% CI: 2.2, 3.6), and hiatal hernia (HR = 1.8, 95% CI: 1.2, 2.7), while Black race (HR = 0.58, 95% CI: 0.42, 0.79), being overweight (HR = 0.79, 95% CI: 0.66, 0.95), and obesity (HR = 0.51, 95% CI: 0.36, 0.71) were associated with a lower incidence. Among women, older age, rural residence, greater height, chronic cough, and umbilical hernia were associated with inguinal hernia.

3. In abstract of the study of "Risk factors for inguinal hernia in women: a case-control study. The Coala Trial Group" by Liem MS, van der Graaf Y, Zwart RC, Geurts I, van Vroonhoven TJ., posted in PubMed, researchers indicated in a hospital-based case-control study of 89 female patients with an incident inguinal hernia and 176 age-matched female controls. Activity since birth with two validated questionnaires was measured and smoking habits, medical and operation history, Quetelet index (kg/m2), and history of pregnancies and deliveries were recorded. Response for cases was 81% and for controls 73%. Total physical activity was not associated with inguinal hernia (univariate odds ratio (OR) = 0.8, 95% confidence interval (CI) 0.6-1.1), but high present sports activities was associated with lessinguinal hernia (multivariate OR = 0.2, 95% CI 0.1-0.7). Obesity (Quetelet index > 30) was also protective for inguinal hernia (OR = 0.2, 95% CI 0.04-1.0). Independent risk factors were positive family history (OR = 4.3, 95% CI 1.9-9.7) and obstipation (OR = 2.5, 95% CI 1.0-6.7).

4. In a study of "The effect of tobacco consumption and body mass index on complications and hospital stay after inguinal hernia surgery" by Lindström D, Sadr Azodi O, Bellocco R, Wladis A, Linder S, Adami J., posted in PubMed, researchers found that smoking increases the risk of postoperative complications even in minor surgery such as inguinal hernia procedures. Obesity increases hospitalization after inguinal hernia surgery. The Swedish version of oral moist tobacco, snus, does not seem to affect the complication rate after hernia surgery at all.

5. According to the study of "Inguinal hernia recurrence: classification and approach" by Campanelli G, Pettinari D, Nicolosi FM, Cavalli M, Avesani EC., posted in PubMed, researchers found that following a simple anatomo-clinical classification into three types that could be used to orient surgical strategy, were: type R1--first recurrence of "high" oblique external reducible hernia with small (<2 cm) defect in non-obese patients after pure tissue or mesh repair; type R2--first recurrence of "low" direct reducible hernia with small (<2 cm) defect in non-obese patients after pure tissue or mesh repair; and type R3--all other recurrences, including femoral recurrences, recurrent groin hernia with large defect (inguinaleventration), multi-recurrent hernias, non-reducible contralateral primary or recurrent hernia, and situations compromised by aggravating factors (e.g. obesity) or otherwise not easily included in R1 or R2 after pure tissue or mesh repair.

6. Etc.

Treatments of Obesity and Inguinal Hernia
1. According to the study of "Local anesthetic hernia repair in overweight and obese patients" by Reid TD, Sanjay P, Woodward A, posted in PubMed, researchers found that Local anesthetic inguinal hernia repair in the obese is safe and well tolerated. Use of a large volume local anesthetic mixture is recommended in overweight and obese patients.

2.In the study of "Factors determining the doses of local anesthetic agents in unilateral inguinal hernia repair" by Kulacoglu H, Ozyaylali I, Yazicioglu D., popsted in PubMed, researchers indicated that again, the feasibility of local anesthesia in elective inguinal hernia repair in all patient groups with different characteristics. The mean and maximum doses of local anesthetic agents were well within safety limits, even in recurrent and large hernias. Younger age, large hernias, recurrent hernias, omental mass in the hernia sac, high BMI, and duration of operation might be the factors affecting local anesthetic doses. The significant independent parameters in the multivariate analysis were duration of operation, sac content, and BMI for lidocaine dose, whereas the duration of operation and sac content were determinative for the sum volume of lidocaine and bupivacaine.

3. Etc.
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The Best Way to prevent, treat your disease, including Obesity
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Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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