Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But adding a slice of ginger will solve the problem.
According to the joint study lead by the Ben Gurion University of the Negev, Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), a flavonoid found in green tea exhibited anti-oxidant/anti-inflammatory effects against various diseases, including asthma.
The study also demonstrated the function of Kaempferol in reduced oxidative stress through scavenging free radicals and superoxide radicals effects as well as preserving the activity of various anti-oxidant enzymes in attenuated production of pro inflammatory cytokins.
In fact, evidence from in vitro and in vivo assays, postulated that aqueous fraction of green tea also exerted anti-asthmatic signaling activity in ovalbumin-induced asthmatic model.
Further more, in the study of mice induced asthma by an ovalbumin, aqueous extract of green tea displayed a potent anti-asthmatic activity by increasing the expression level of tumor necrosis factor-beta, (a protein involved production of one of the inflammatory cytokin in the acute phase) and interferon-gamma in displacement of immune function against microbial infection and decreased expression of anti-asthmatic cytokines in the lung.
More importantly, green tea alleviated asthmatic symptoms by increasing the expression of Th1 cell-in regulated the production of interferon-gamma and interleukin (IL)-2, proinflammatory cytokins and tumour necrosis factor.
Promissingly, another green tea constituent, namely Chafuroside A (CFA), water-soluble flavone C-glycoside, in an experimental asthma/chronic obstructive pulmonary disease (COPD)-rat model, treatment with Chafuroside A at 0.5mg/kg, 1.0mg/kg could attenuate inflammatory symptoms and ameliorate antigen-induced airway inflammation, respectively.
Dr, Onoue S, the lead author in above study said, " A self-assembled micellar (SAM) formulation might be an efficacious approach for enhancing the therapeutic potential of CFA for treatment of inflammatory diseases".
Unfortunately, there are few reports suggested that green tea-induced asthma in tea-sensitive patients, as epigallociatechin gallate induced histamine release through IgE-mediated response.
Taking together, there is no doubt that green tea may be considered as a functional food for prevention and treatment of asthma, but people with tea sensitive syndrome should avoid drinking green tea unless with approval of related field specialist.
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Author: Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Kaempferol, a potential cytostatic and cure for inflammatory disorders by Rajendran P1, Rengarajan T1, Nandakumar N2, Palaniswami R3, Nishigaki Y1, Nishigaki I4.(PubMed)
(2) An aqueous extract of green tea Camellia sinensis increases expression of Th1 cell-specific anti-asthmatic markers by Heo JC1, Rho JR, Kim TH, Kim SY, Lee SH.(PubMed)
(3) Self-assembled micellar formulation of chafuroside A with improved anti-inflammatory effects in experimental asthma/COPD-model rats by Onoue S1, Matsui T, Aoki Y, Ishida H, Nukaya H, Kou K, Yamada S.(PubMed)
