Health Benefits of Sencha Tea - Skin cancer
In the determination of EGCG((-)-Epigallocatechin-3-gallate) and DZNep( 3-deazaneplanocin A ) as the important candidate chemopreventive agents against skin cancer of the study of "(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells" by Choudhury SR, Balasubramanian S, Chew YC, Han B, Marquez VE, Eckert RL[2e]., researchers found that EGCG and DZNep, independently and in combination, reduce the level of PcG proteins including Ezh2, eed, Suz12, Mel18 and Bmi-1 that lead to proteasome-associated degradation.
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