Prostate cancer is a condition in which the cells of prostate has become cancerous, causing abnormal cell growth with possibility of spreading to the distant parts of the body.
Most prostate cancers are slow growing and prostate cancer may be detected during physical (rectum) exams.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. Adding a slice of ginger will do the trick.
According to the Fu Jen Catholic University, New Taipei City, catechin nanoemulsion preparation showed a highest inhibition of growth of PC-3 tumor cells, with concentration being 15.4 μg/mL and 8.5 μg/mL.
The inhibition of prostate cancer cell line is observed in cell cycle arrest by regulated proteins involved cell cycle division, namely cyclin A, cyclin B, cyclin-dependent kinase 2, and cyclin-dependent kinase 1 expression and activated cell atopotosis and survival.
Dr. Tsai YJ, the lead author said, " catechin extract and nanoemulsion could induce apoptosis of PC-3 cells through decrease in B-cell lymphoma 2 (bcl-2) expression and increase in cytochrome c expression( in induction of apoptosis) for activation of caspase-3, caspase-8, and caspase-9 (involved cell death)".
Furthermore, in the recruited 404 PCA cases and 395 controls from the same hospital who completed data on habitual tea consumption, including green, oolong, black and pu'er tea regular green drinkers have a significantly reduced risk in prostate cancer development.
The review of inverse relation of tea drinkers and risk of prostate cancer has shown explicitly:
1. total of 32 cases and 50 controls reported habitual green tea drinking, showing an adjusted OR of 0.60 (95% confidence interval (CI): 0.37, 0.98).
2. A moderate excess risk was observed among the habitual pu'er tea drinkers (OR=1.44, 95% CI: 1.02, 1.91).
3. A significantly lower intake of EGCG was observed among cases (54.4 mg) than the controls (72.5 mg).
Additionally, the differentiation of 7 observational studies and 3 randomized controlled trials retrieved from Cochrane Library, PubMed, Sciencedirect Online, and hand searching.the database, also reveal an interest correlated incidence of PCa decrease with each 1 cup/day increase of green tea.
According of the study, "higher green tea consumption was linearly reduced PCa risk with more than 7 cups/day and green tea catechins were effective for preventing PCa".
Collectively, green tea consumption is associated inversely to risk of PCA but injection of large amount of green tea supplement should be taken with care in prevented toxicity.
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Author: Kyle J. Norton, Master of Nutrition
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study by Tomata Y1, Sugiyama K2, Kaiho Y2, Honkura K2, Watanabe T2, Zhang S2, Sugawara Y2, Tsuji I2(PubMed)
(2) Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia by Biasibetti R1, Tramontina AC, Costa AP, Dutra MF, Quincozes-Santos A, Nardin P, Bernardi CL, Wartchow KM, Lunardi PS, Gonçalves CA.(PubMed)
(3) Coffee, tea, and caffeine consumption and prevention of late-life cognitive decline and dementia: a systematic review by Panza F1, Solfrizzi V, Barulli MR, Bonfiglio C, Guerra V, Osella A, Seripa D, Sabbà C, Pilotto A, Logroscino G.(PubMed)