Wednesday, December 12, 2018

The Beverage Which Alleviates Symptoms and Treats Irritable Bowel Syndrome

Black tea may have a therapeutic and positive effect in reduced risk and treatment of irritable bowel syndrome, some scientists suggested.

Black tea is a type of tea with more oxidized compared to green tea, made from leaves of the shrub (or small tree) Camellia sinensis.

Irritable bowel syndrome is a common condition of digestive disorder, affecting the large intestine without inducing evidence of intestinal damage.

According to worldwide statistic, irritable bowel syndrome (IBS) is the most common functional gastrointestinal (GI) disorder, affecting approximately 10–15% general population.

Scientists as of today do not the exact causes of irritable bowel syndrome. However, some researchers suggested that some conditions such as abnormal gastrointestinal (GI) tract movements,..... and a disruption in neurotransmitted information to the GI tract are associated to increased risk of the disease.

Women who are less than 35 of age are more susceptible to the disease onset in compared to men.


Most common symptoms of IBS are long-term gastrointestinal discomforts, including abdominal cramping or pain, bloating, gassiness,.... and altered bowel habits. Some women with IBS also experience symptoms worsened during periods and menstruation

If you have some symptoms above, you may have IBS. Please check with your doctor to rule out the possibility.


In the study of symptoms of gastrointestinal (GI) motility in patients with irritable bowel syndrome who exhibited reduced levels of serotonin 5-HT3 which play an important role in regulating the motility in the entire GI tract, researchers found that application of black tea and its major polyphenolic pigment thearubigins (TR) enhance movement of the gastrointestinal tract and stimulating gut emptying.

The additional assessment also discovered, black tea and its bioactive component also improved symptoms of diarrhea through promoting prokinetic activity with efficiency similar to those of conventional medicine benzoxazole.

Furthermore, in compared the efficacy of black tea extract and injection of ondansetron, a potent antagonist of 5-HT3 receptor used for treatment of nausea and vomiting caused by cancer chemotherapy, in IBS patients researchers indicated that black tea and its major polyphenolic pigment thearubigins (TR) demonstrated significant activity in reduced symptoms of IBS through mediation by the 5-HT3 receptors.


After taking into account other confounders, the researcher suggested, "black tea drinking in moderate concentrations and in proper amount could be useful to abate the GI consequences of IBS. In order to avoid gastro-esophageal reflux, it may be better to use decaffeinated tea".

Moreover, in the examine the tea flavonoids the large group of polyphenols in antioxidative and anti-inflammatory effects, scientists showed that application of epigallocatechin gallate and apigenin isolated from tea in IBS patients demonstrate an impressive activities in reduced expression of proinflammatory cytokines, such as interleukin (IL)-6, IL-8, tumor necrosis factor (TNF)-α, and IL-12, and lower levels of anti-inflammatory cytokine IL-10 in the bloodstream.

Truly, treatment of black tea also expressed a strong effect in reduced levels of plasma concentrations of malondialdehyde (MDA) and nitric oxide (NO) which are found elevated in patients with IBS, thus decreasing lipid peroxidation and alterations in the oxidant-antioxidant enzymatic system function in the contribution of the pathogenesis of IBS.



The effect of antioxidant in reduced overexpression of oxidative stress of black tea was attributed the strong effect of its chemical constituents in inhibited free radicals through stimulated the function of antioxidant in the tea and in the body natural antioxidant defense.
Therefore, the combination restored the ratio of reactive oxygen species and antioxidant produced by tissue in the body.



Dr, Hoensch H, the lead author at the Marienhospital Darmstadt. said, " Dietary supplementation with specific tea-flavonoids could be used for Crohn's disease, ulcerative colitis, and irritable bowel syndrome".

Although, black tea showed a significant effect in inhibited irritable bowel syndrome, the geographic region where the tea was growth, the time of growth and harvested, how the tea is processed overall may contribute the increased or decreased efficacy of the beverage.

Taken together, black tea may be considered as a functional food for reduced risk, inhibited symptoms and treatment of irritable bowel syndrome. However, the intake of black tea extracts should be taken with extreme care, as acute liver toxicity was reported in some medical literature.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Black tea extract and its major polyphenolic pigment may ameliorate the gastrointestinal disorder in irritable bowel syndrome by Jafari K, Faghihi M, Gharibzadeh S.
(2) [Anti-inflammatory effects of tea-flavonoids].[Article in German] by Hoensch H1, Oertel R.(PubMed)

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