Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Artheroclerosis, also known as arteriosclerotic vascular disease is defined as a condition of thickening of the arterial wall as a result of plague accumulation due to building up of fat and cholesterol.
How Obesity associates with Artheroclerosis
1. In a study of "[Left ventricular hypertrophy and thickening of common carotid artery wall in men aged 40 - 54 years with I degree arterialhypertension]." [Article in Russian] by Grigoricheva EA, Sorokin AV, Korovina OV, Pestova DL., posted in PubMed, researchers found that Formation of left ventricular hypertrophy was related to parameters of 24 hour blood pressure monitoring, arterial hypertension in brothers and sisters, body weight, and duration of obesity. Significant medium power relation was obtained between tension of endothelial system of hemostasis (protein C) and severity of left ventricular hypertrophy (correlation coefficient - 0,3). Age, heredity, low density lipoprotein, cholesterol, uric acid level mattered for IMT increase.
2. According to the study of "High rate of increased carotid intima-media thickness and atherosclerotic plaques in Chinese asymptomatic subjects with central obesity" by Ko GT, Chow CC, Leung G, Au-Yeung TW, Chan WB, Lam CS, Lo M, Lee KK., posted in PubMed, researchers concluded that among Hong Kong Chinese asymptomatic subjects with central obesity, there was a high rate of CVD risk factors. We found that 19% of these subjects had carotid atherosclerotic plaques and 10% of them had abnormal IMT (>0.9 mm). Carotid IMT study may serve as an appropriate screening tool to diagnose atherosclerosis in the centrally obese middle-aged population.
3. In the study of "Obesity, atherosclerosis and the vascular endothelium: mechanisms of reduced nitric oxide bioavailability in obese humans" by
I L Williams, S B Wheatcroft, A M Shah and M T Kearney, posted in International Journals of Obesity, researchers wrote in abstract that it is now well established that obesity is an independent risk factor for the development of coronary artery atherosclerosis. The maintenance of vascular homeostasis is critically dependent on the continued integrity of vascular endothelial cell function. A key early event in the development of atherosclerosis is thought to be endothelial cell dysfunction.
4. According to the study of "Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposit" by J Gómez-Ambrosi, C Silva, J C Galofré, J Escalada, S Santos, D Millán, N Vila, P Ibañez, M J Gil, V Valentí, F Rotellar, B Ramírez, J Salvador and G Frühbeck, posted in International Journals of Obesity, researchers concluded that Given the elevated concentrations of cardiometabolic risk factors reported herein in non-obese individuals according to BMI but obese based on body fat, the inclusion of body composition measurements together with morbidity evaluation in the routine medical practice both for the diagnosis and the decision-making for instauration of the most appropriate treatment of obesity is desirable.
5. Etc.
Treatments of Obesity and Artheroclerosis
1. According to the study of "Acute effects of epigallocatechin gallate from green tea on oxidation and tissue incorporation of dietary lipids in mice fed a high-fat diet" by M Friedrich, K J Petzke, D Raederstorff, S Wolfram and S Klaus, posted in International Journals of Obesity, researchers found that Anti-obesity effects of EGCG can be explained by a decreased food digestibility affecting substrate metabolism of intestinal mucosa and liver, leading to increased post-prandial fat oxidation and reduced incorporation of dietary lipids into tissues.
2. in P54 of Poster session III: Physical activity, exercise, nutrition and body composition, "The Effect of Long-term Taijiquan Practice on the Lipid Metabolism and Hormone Levels among Obese University Students" by HaiJun Zhang1, HaiLi Zhang and XiaoTao Guo. posted in International Journals of Obesity, researchers concluded that Long-term Taijiquan practice improves the components of blood-lipid, promotes the fat catabolism, adjusts the endocrine, and is helpful for health, fitness and losing weight.
3. In P63 of Poster session III: Physical activity, exercise, nutrition and body composition, "Effect of the Diabolo Exercise on Aged Women" by Xinbao Wang1 and Dawu Huang, posted in International Journals of Obesity, researchers found that Diabolo exercise has a good effect on reducing obesity and improving the function of the cardiovascular system for aged women.
4. Etc.Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Wednesday, May 25, 2016
Most common Diseases of 50plus: The Obesity' Research and Studies of Weight Loss and Whey Protein
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
The research and studies of Weight Loss and Whey Protein
In a study of 90 overweight and obese participants were randomly assigned to 1 of 3 treatment groups for 23 wk: 1) WP; 2) SP (each providing ~56 g/d of protein and 1670 kJ/d); or 3) an isoenergetic amount of CHO by Beltsville Human Nutrition Research Center (1), indicated that after 23 wk, body weight and composition did not differ between the groups consuming the SP (Soy protein) and WP (Whey protein) or between SP and CHO (an isoenergetic amount of carbohydrate); however, body weight and fat mass of the group consuming the WP were lower by 1.8 kg (P < 0.006) and 2.3 kg (P < 0.005), respectively, than the group consuming CHO. Lean body mass did not differ among any of the groups. Waist circumference was smaller in the participants consuming WP than in the other groups (P < 0.05).
Whey protein diet is superior than either Soy protein or isoenergetic amount of carbohydrate for obese people to loss weight.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1)" Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults". by Baer DJ, Stote KS, Paul DR, Harris GK, Rumpler WV, Clevidence BA. PubMed
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
The research and studies of Weight Loss and Whey Protein
In a study of 90 overweight and obese participants were randomly assigned to 1 of 3 treatment groups for 23 wk: 1) WP; 2) SP (each providing ~56 g/d of protein and 1670 kJ/d); or 3) an isoenergetic amount of CHO by Beltsville Human Nutrition Research Center (1), indicated that after 23 wk, body weight and composition did not differ between the groups consuming the SP (Soy protein) and WP (Whey protein) or between SP and CHO (an isoenergetic amount of carbohydrate); however, body weight and fat mass of the group consuming the WP were lower by 1.8 kg (P < 0.006) and 2.3 kg (P < 0.005), respectively, than the group consuming CHO. Lean body mass did not differ among any of the groups. Waist circumference was smaller in the participants consuming WP than in the other groups (P < 0.05).
Whey protein diet is superior than either Soy protein or isoenergetic amount of carbohydrate for obese people to loss weight.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
(1)" Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults". by Baer DJ, Stote KS, Paul DR, Harris GK, Rumpler WV, Clevidence BA. PubMed
Most Common Disease of 50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Polymyalagia Arthritis (Rheumatica): The Complications(2)
Kyle J. Norton (Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Polymyalgia Arthritis (Rheumatica)
Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.
The Complications(2)
The Most common complications for people with Polymyalgia Rheumatica(PMR)
1. Ischemic complications
Patient with Polymyalgia Rheumatica(PMR) are found to have an lower risk of developing ischemic events, according to University of Barcelona(63). Dr. Narváez J and the research team at the joint study lead by Hospital Universitario de Bellvitge-IDIBELL said," Patients with GCA presenting with apparently isolated PMR have a significant risk of developing transient or permanent disease-related ischemic complications" and "these complications occurred in 50% of the cases"(64). Some patient of PMR with thrombocytosis also are found to at greatest risk for the development of stroke as well(65).
2. Vascular events
DR. Staud R. said," Patients with polymyalgia rheumatica had a 2.6-fold increased risk for vascular events at a median 7.8 y"(66). Youngest age groups patient with Polymyalgia Rheumatica(PMR) are associated to the greatest risk of vascular events in comparison to other age group(67).
3. Interspinous bursitisInterspinous bursitis, a frequent finding in the lumbar spine of patients with PMR is found to have a potential cause of spinal symptoms probably due to the presence of cervical and lumbar bursitis(68). Other study suggested that the complications of low back pain reported by patients with PMR may also be result of Inflammation of lumbar bursae, the Istituto di Ricovero e Cura a Carattere Scientifico study suggested(69).
4. Shoulder inflammation
Shoulder inflammation is found common in 50%patient with PMR(70). But according to the research lead by Dr. Curran JF , shoulder arthritis may be result of inflammatory, degenerative, and septic arthritis and rarely the initial joint involved in rheumatoid arthritis and generally the symptoms is respond to the basic management for rheumatoid arthritis(71).
5. Stress fractures
One of the complication of rheumatic disease, including Polymyalgia Rheumatica(PMR) may often be delayed or missed in diagnosis, leading to improper treatment, the Sourasky Medical Center suggested(72). Dr. Mäenpää HM and the research team at the Rheumatism Foundation Hospital said,"a patient with rheumatic disease experiences sudden and unexplained pain localised in the forefoot, above the ankle, below the knee, or in the pelvis, a stress fracture should be suspected"(73).
6. Infection diseases
Patient with Polymyalgia Rheumatica(PMR) are found to be susceptible to the complications of infectious diseases, such as Chronic Epstein-Barr virus infection(74), Mycoplasma pneumoniae infection(75),........
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
REFERENCES
(63) Development of ischemic complications in patients with giant cell arteritis presenting with apparently isolatedpolymyalgia rheumatica: study of a series of 100 patients by Hernández-Rodríguez J1, Font C, García-Martínez A, Espígol-Frigolé G, Sanmartí R, Cañete JD, Grau JM, Cid MC.(PubMed)
(64) Prevalence of ischemic complications in patients with giant cell arteritis presenting with apparently isolatedpolymyalgia rheumatica by Narváez J1, Estrada P2, López-Vives L2, Ricse M2, Zacarías A2, Heredia S2, Gómez-Vaquero C2, Nolla JM2.(PubMed)
(65) Thrombocytosis in polymyalgia rheumatica: an additional diagnostic criterion and possible risk factor for ischemic complications?by Harten P, Seyfarth B, Löffler H.(PubMed)
(66) Patients with polymyalgia rheumatica had a 2.6-fold increased risk for vascular events at a median 7.8 y by Staud R.(PubMed)
(67) Risk of vascular events in patients with polymyalgia rheumatica by Hancock AT1, Mallen CD2, Muller S1, Belcher J1, Roddy E1, Helliwell T1, Hider SL1.(PubMed)
(68) Interspinous bursitis is common in polymyalgia rheumatica, but is not associated with spinal pain by Camellino D, Paparo F, Morbelli S, Cutolo M, Sambuceti G, Cimmino MA.(PubMed)
(69) Lumbar interspinous bursitis in active polymyalgia rheumatica by Salvarani C1, Barozzi L, Boiardi L, Pipitone N, Bajocchi GL, Macchioni PL, Catanoso M, Pazzola G, Valentino M, De Luca C, Hunder GG.(PubMed)
(70)Shoulder arthritis. Distinguishing among the many causes of inflammation by Ellman MH, Brown NL, Curran JJ.(PubMed)
(71) Rheumatologic aspects of painful conditions affecting the shoulder by Curran JF, Ellman MH, Brown NL.(PubMed)
(72) Insufficiency fractures in rheumatic patients: misdiagnosis and underlying characteristics by Elkayam O1, Paran D, Flusser G, Wigler I, Yaron M, Caspi D.(PubMed)
(73) Insufficiency fractures in patients with chronic inflammatory joint diseases by Mäenpää HM1, Soini I, Lehto MU, Belt EA.(PubMed)
(74) "Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica by Buchwald D1, Sullivan JL, Leddy S, Komaroff AL.(PubMed)
(75) Synchronous variations of the incidence of temporal arteritis and polymyalgia rheumatica in different regions of Denmark; association with epidemics of Mycoplasma pneumoniae infection by Elling P1, Olsson AT, Elling H.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed. A major restriction of joint movement range was frequent in the shoulder but uncommon in other joints(1).
Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalgia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia
Polymyalgia Arthritis (Rheumatica)
Polymalgia Arthritis is defined as a condition a common inflammatory rheumatic disease which causes pain, stiffness and tenderness in large muscles, including muscles shoulders and pelvic girdle as a result of the presence of a synovitis in proximal joints and periarticular structures.
The Complications(2)
The Most common complications for people with Polymyalgia Rheumatica(PMR)
1. Ischemic complications
Patient with Polymyalgia Rheumatica(PMR) are found to have an lower risk of developing ischemic events, according to University of Barcelona(63). Dr. Narváez J and the research team at the joint study lead by Hospital Universitario de Bellvitge-IDIBELL said," Patients with GCA presenting with apparently isolated PMR have a significant risk of developing transient or permanent disease-related ischemic complications" and "these complications occurred in 50% of the cases"(64). Some patient of PMR with thrombocytosis also are found to at greatest risk for the development of stroke as well(65).
2. Vascular events
DR. Staud R. said," Patients with polymyalgia rheumatica had a 2.6-fold increased risk for vascular events at a median 7.8 y"(66). Youngest age groups patient with Polymyalgia Rheumatica(PMR) are associated to the greatest risk of vascular events in comparison to other age group(67).
3. Interspinous bursitisInterspinous bursitis, a frequent finding in the lumbar spine of patients with PMR is found to have a potential cause of spinal symptoms probably due to the presence of cervical and lumbar bursitis(68). Other study suggested that the complications of low back pain reported by patients with PMR may also be result of Inflammation of lumbar bursae, the Istituto di Ricovero e Cura a Carattere Scientifico study suggested(69).
4. Shoulder inflammation
Shoulder inflammation is found common in 50%patient with PMR(70). But according to the research lead by Dr. Curran JF , shoulder arthritis may be result of inflammatory, degenerative, and septic arthritis and rarely the initial joint involved in rheumatoid arthritis and generally the symptoms is respond to the basic management for rheumatoid arthritis(71).
5. Stress fractures
One of the complication of rheumatic disease, including Polymyalgia Rheumatica(PMR) may often be delayed or missed in diagnosis, leading to improper treatment, the Sourasky Medical Center suggested(72). Dr. Mäenpää HM and the research team at the Rheumatism Foundation Hospital said,"a patient with rheumatic disease experiences sudden and unexplained pain localised in the forefoot, above the ankle, below the knee, or in the pelvis, a stress fracture should be suspected"(73).
6. Infection diseases
Patient with Polymyalgia Rheumatica(PMR) are found to be susceptible to the complications of infectious diseases, such as Chronic Epstein-Barr virus infection(74), Mycoplasma pneumoniae infection(75),........
All Forms of Arthritis are Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
REFERENCES
(63) Development of ischemic complications in patients with giant cell arteritis presenting with apparently isolatedpolymyalgia rheumatica: study of a series of 100 patients by Hernández-Rodríguez J1, Font C, García-Martínez A, Espígol-Frigolé G, Sanmartí R, Cañete JD, Grau JM, Cid MC.(PubMed)
(64) Prevalence of ischemic complications in patients with giant cell arteritis presenting with apparently isolatedpolymyalgia rheumatica by Narváez J1, Estrada P2, López-Vives L2, Ricse M2, Zacarías A2, Heredia S2, Gómez-Vaquero C2, Nolla JM2.(PubMed)
(65) Thrombocytosis in polymyalgia rheumatica: an additional diagnostic criterion and possible risk factor for ischemic complications?by Harten P, Seyfarth B, Löffler H.(PubMed)
(66) Patients with polymyalgia rheumatica had a 2.6-fold increased risk for vascular events at a median 7.8 y by Staud R.(PubMed)
(67) Risk of vascular events in patients with polymyalgia rheumatica by Hancock AT1, Mallen CD2, Muller S1, Belcher J1, Roddy E1, Helliwell T1, Hider SL1.(PubMed)
(68) Interspinous bursitis is common in polymyalgia rheumatica, but is not associated with spinal pain by Camellino D, Paparo F, Morbelli S, Cutolo M, Sambuceti G, Cimmino MA.(PubMed)
(69) Lumbar interspinous bursitis in active polymyalgia rheumatica by Salvarani C1, Barozzi L, Boiardi L, Pipitone N, Bajocchi GL, Macchioni PL, Catanoso M, Pazzola G, Valentino M, De Luca C, Hunder GG.(PubMed)
(70)Shoulder arthritis. Distinguishing among the many causes of inflammation by Ellman MH, Brown NL, Curran JJ.(PubMed)
(71) Rheumatologic aspects of painful conditions affecting the shoulder by Curran JF, Ellman MH, Brown NL.(PubMed)
(72) Insufficiency fractures in rheumatic patients: misdiagnosis and underlying characteristics by Elkayam O1, Paran D, Flusser G, Wigler I, Yaron M, Caspi D.(PubMed)
(73) Insufficiency fractures in patients with chronic inflammatory joint diseases by Mäenpää HM1, Soini I, Lehto MU, Belt EA.(PubMed)
(74) "Chronic Epstein-Barr virus infection" syndrome and polymyalgia rheumatica by Buchwald D1, Sullivan JL, Leddy S, Komaroff AL.(PubMed)
(75) Synchronous variations of the incidence of temporal arteritis and polymyalgia rheumatica in different regions of Denmark; association with epidemics of Mycoplasma pneumoniae infection by Elling P1, Olsson AT, Elling H.(PubMed)
Traditional Chinese Medicine Herbal Therapy - Popular Herbal Ba Qia (Rhizoma Smilacis Chinensis)
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Ba Qia also known as Rhizome of chinaroot greenbrier, Smilax china L., is a genus Smilax, belonging to the family Liliaceae, native to Southeast Asia. The warm and sweet herb has been used in TCM to treat rheumatoid arthritis, muscle numbness, diarrhea, dysentery, gonorrhea and hemorrhoids, as it expels wind-dampness, alleviate pain, eliminates toxins and relieves swelling by enhancing the functions of kidney and liver channels.
Ingredients
2. Chronic pelvic inflammatory disease
Also in rat study, researchers found that extracted substances of Ba Qia promote the normal levels of Interleukin-2 and tenamfetamine (INN) and can be used to reduce the symptoms and treat chronic pelvic inflammatory disease caused by E. coli.
3. Blood circulation
In mice study, Ba Qia decoction 100g were given to mice orally in 7 consecutive days, researchers found that it significantly prolongs the aPTT and inhibits platelet aggregation that suggested that Ba Qia decoction might be used to promote blood circulation, and use in the inhibition of endogenous platelet aggregation and anti-coagulation.
4. Prostate health
In rat study, researchers found that Ethyl acetate, Butanol, Saponin extracted from Ba Qia effectively reduce total prostate specific antigen (TPSA) index and treat Non-bacterial prostatitis.
5. Tumors
Publicized by JOURNAL OF BASIC AND CLINICAL ONCOLOGY in 2007 second edition, researchers found that extracted Ethyl acetate from Ba Qia contains a anti tumor property by scavenging and directly killing the tumor cells.
6. Anti-diabetes Foot Ulcer
Herbal formula formula contains six Chinese medical herbs, including Radix Astragali, Radix Rehmanniae, Rhizoma Smilacis Chinensis, Rhizoma Atractylodis Macrocephalae extracts can modify cellular glucose homeostasis, according to the study of “Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis” by Chan CM, Chan YW, Lau CH, Lau TW, Lau KM, Lam FC, Che CT, Leung PC, Fung KP, Lau CB, Ho YY., posted in PubMed(1).
7. Anticonvulsant and neurotoxicity
Ethanolic extract and ethyl acetate fraction of Ba Qia reduced significantly (P < 0.001) by EESC at a dose level of 400 mg/kg and EAF at both higher dose levels (200 and 400 mg/kg). In PTZ model, the seizure latency was prolonged by all the test groups, according to the study of “Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice” by Vijayalakshmi A, Ravichandiran V, Anbu J, Velraj M, Jayakumari S., posted in PubMed(2).
8. Anti-inflammatory activities
Seiboldogenin was isolated from ethyl acetate fraction of Ba Qia crude extract exhibited significant inhibition (p<0.05) of carrageenan-induced hind paw oedema at the doses of 10 and 50mg/kg. Computational molecular docking showed its molecular interaction with important amino acid residues in the catalytic site of lipoxygenase, revealing its potential binding mode at molecular level. according to the study of “Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies” by Khan I, Nisar M, Ebad F, Nadeem S, Saeed M, Khan H, Samiullah, Khuda F, Karim N, Ahmad Z., posted in PubMed(3).
9. Anti-hyperuricemic and nephroprotective effects
Ba Qia exhibits anti-hyperuricemic and nephroprotective activity in hyperuricemic animals and prevents prevented the renal damage against tubulointerstitial pathologies in hyperuricemic rats, according to the study of “Anti-hyperuricemic and nephroprotective effects of Smilax china L.” by Chen L, Yin H, Lan Z, Ma S, Zhang C, Yang Z, Li P, Lin B., posted in PubMed(4).
10. Breast tumor
Six polyphenols were obtained on the basis of a bioassay-guided separation of the ethyl acetate extract from Ba Qia showed anti-tumor activities against MCF-7 and MDA-MB-231 with IC50 value of 2.1-38.9mug/mL, and can induce apoptosis for MCF-7 and MDA-MB-231, according to the study of “Cytotoxic polyphenols against breast tumor cell in Smilax china L.” by Wu LS, Wang XJ, Wang H, Yang HW, Jia AQ, Ding Q., posted in PubMed(5).
11. Anti-cancer
Eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay and clonogenic assay, the fraction rich in flavonoids had show good activity against HeLa cells that suggest cell cycle arrest at G(1) phase and induce apoptosis as a mechanism by which KG exerts an antiproliferative effect.effect, according to the study of ” A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines” by Li YL, Gan GP, Zhang HZ, Wu HZ, Li CL, Huang YP, Liu YW, Liu JW., posted in PubMed(6).
12. Arthritis
The decoction of Ba Qia significantly inhibit adjunctive arthritis mouse’s secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell, according to the study of “[Effect of Smilax china on adjunctive arthritis mouse].[Article in Chinese]” by Lü Y, Chen D, Deng J, Tian L., posted in PubMed(7).
13. Antioxidants
Methanol extract (Me) revealed the presence of high 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (IC50 7.4 microg/ml) and protective property of cell’s viability. Further fractionation with various solvent extraction and assay showed high levels of DPPH free radical scavenging activity in the ethyl acetate, butanol and water extracted fractions, according to the study of “Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root” by Lee SE, Ju EM, Kim JH., posted in PubMed(8)
14. Etc.
Side effects
1. Nausea, irritation and vomiting.
2. No other side effect is known yet.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
If you like what you read, please follow me at http://twitter.com/kylejnortonSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16891069(2) http://www.ncbi.nlm.nih.gov/pubmed/21455417
(3) http://www.ncbi.nlm.nih.gov/pubmed/19007873
(4) http://www.ncbi.nlm.nih.gov/pubmed/21420478
(5) http://www.ncbi.nlm.nih.gov/pubmed/20685245
(6) http://www.ncbi.nlm.nih.gov/pubmed/17606345
(7) http://www.ncbi.nlm.nih.gov/pubmed/14535017
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Ba Qia also known as Rhizome of chinaroot greenbrier, Smilax china L., is a genus Smilax, belonging to the family Liliaceae, native to Southeast Asia. The warm and sweet herb has been used in TCM to treat rheumatoid arthritis, muscle numbness, diarrhea, dysentery, gonorrhea and hemorrhoids, as it expels wind-dampness, alleviate pain, eliminates toxins and relieves swelling by enhancing the functions of kidney and liver channels.
Ingredients
1. Steroidal saponins
2. Solanidine
2. Solanidine
3. Alkaloid
4. Essential oil
5. Tannin
6. Sugar
7. Resin
8. Phytosterol
9. Starch10. Etc.
Health benefits
4. Essential oil
5. Tannin
6. Sugar
7. Resin
8. Phytosterol
9. Starch10. Etc.
Health benefits
1. Immune system
In rat study, researchers found that extracted Buttanol of Ba Qia enhances the functions of Interleukin-2 a type of cytokine immune system signaling molecule in fighting against oxidation and inhibits calcineurin (CaN) activity.
In rat study, researchers found that extracted Buttanol of Ba Qia enhances the functions of Interleukin-2 a type of cytokine immune system signaling molecule in fighting against oxidation and inhibits calcineurin (CaN) activity.
2. Chronic pelvic inflammatory disease
Also in rat study, researchers found that extracted substances of Ba Qia promote the normal levels of Interleukin-2 and tenamfetamine (INN) and can be used to reduce the symptoms and treat chronic pelvic inflammatory disease caused by E. coli.
3. Blood circulation
In mice study, Ba Qia decoction 100g were given to mice orally in 7 consecutive days, researchers found that it significantly prolongs the aPTT and inhibits platelet aggregation that suggested that Ba Qia decoction might be used to promote blood circulation, and use in the inhibition of endogenous platelet aggregation and anti-coagulation.
4. Prostate health
In rat study, researchers found that Ethyl acetate, Butanol, Saponin extracted from Ba Qia effectively reduce total prostate specific antigen (TPSA) index and treat Non-bacterial prostatitis.
5. Tumors
Publicized by JOURNAL OF BASIC AND CLINICAL ONCOLOGY in 2007 second edition, researchers found that extracted Ethyl acetate from Ba Qia contains a anti tumor property by scavenging and directly killing the tumor cells.
6. Anti-diabetes Foot Ulcer
Herbal formula formula contains six Chinese medical herbs, including Radix Astragali, Radix Rehmanniae, Rhizoma Smilacis Chinensis, Rhizoma Atractylodis Macrocephalae extracts can modify cellular glucose homeostasis, according to the study of “Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis” by Chan CM, Chan YW, Lau CH, Lau TW, Lau KM, Lam FC, Che CT, Leung PC, Fung KP, Lau CB, Ho YY., posted in PubMed(1).
7. Anticonvulsant and neurotoxicity
Ethanolic extract and ethyl acetate fraction of Ba Qia reduced significantly (P < 0.001) by EESC at a dose level of 400 mg/kg and EAF at both higher dose levels (200 and 400 mg/kg). In PTZ model, the seizure latency was prolonged by all the test groups, according to the study of “Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice” by Vijayalakshmi A, Ravichandiran V, Anbu J, Velraj M, Jayakumari S., posted in PubMed(2).
8. Anti-inflammatory activities
Seiboldogenin was isolated from ethyl acetate fraction of Ba Qia crude extract exhibited significant inhibition (p<0.05) of carrageenan-induced hind paw oedema at the doses of 10 and 50mg/kg. Computational molecular docking showed its molecular interaction with important amino acid residues in the catalytic site of lipoxygenase, revealing its potential binding mode at molecular level. according to the study of “Anti-inflammatory activities of Sieboldogenin from Smilax china Linn.: experimental and computational studies” by Khan I, Nisar M, Ebad F, Nadeem S, Saeed M, Khan H, Samiullah, Khuda F, Karim N, Ahmad Z., posted in PubMed(3).
9. Anti-hyperuricemic and nephroprotective effects
Ba Qia exhibits anti-hyperuricemic and nephroprotective activity in hyperuricemic animals and prevents prevented the renal damage against tubulointerstitial pathologies in hyperuricemic rats, according to the study of “Anti-hyperuricemic and nephroprotective effects of Smilax china L.” by Chen L, Yin H, Lan Z, Ma S, Zhang C, Yang Z, Li P, Lin B., posted in PubMed(4).
10. Breast tumor
Six polyphenols were obtained on the basis of a bioassay-guided separation of the ethyl acetate extract from Ba Qia showed anti-tumor activities against MCF-7 and MDA-MB-231 with IC50 value of 2.1-38.9mug/mL, and can induce apoptosis for MCF-7 and MDA-MB-231, according to the study of “Cytotoxic polyphenols against breast tumor cell in Smilax china L.” by Wu LS, Wang XJ, Wang H, Yang HW, Jia AQ, Ding Q., posted in PubMed(5).
11. Anti-cancer
Eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay and clonogenic assay, the fraction rich in flavonoids had show good activity against HeLa cells that suggest cell cycle arrest at G(1) phase and induce apoptosis as a mechanism by which KG exerts an antiproliferative effect.effect, according to the study of ” A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines” by Li YL, Gan GP, Zhang HZ, Wu HZ, Li CL, Huang YP, Liu YW, Liu JW., posted in PubMed(6).
12. Arthritis
The decoction of Ba Qia significantly inhibit adjunctive arthritis mouse’s secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell, according to the study of “[Effect of Smilax china on adjunctive arthritis mouse].[Article in Chinese]” by Lü Y, Chen D, Deng J, Tian L., posted in PubMed(7).
13. Antioxidants
Methanol extract (Me) revealed the presence of high 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity (IC50 7.4 microg/ml) and protective property of cell’s viability. Further fractionation with various solvent extraction and assay showed high levels of DPPH free radical scavenging activity in the ethyl acetate, butanol and water extracted fractions, according to the study of “Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root” by Lee SE, Ju EM, Kim JH., posted in PubMed(8)
14. Etc.
Side effects
1. Nausea, irritation and vomiting.
2. No other side effect is known yet.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
If you like what you read, please follow me at http://twitter.com/kylejnortonSources
(1) http://www.ncbi.nlm.nih.gov/pubmed/16891069(2) http://www.ncbi.nlm.nih.gov/pubmed/21455417
(3) http://www.ncbi.nlm.nih.gov/pubmed/19007873
(4) http://www.ncbi.nlm.nih.gov/pubmed/21420478
(5) http://www.ncbi.nlm.nih.gov/pubmed/20685245
(6) http://www.ncbi.nlm.nih.gov/pubmed/17606345
(7) http://www.ncbi.nlm.nih.gov/pubmed/14535017
Most common Diseases of 50plus: The Obesity' Articles - Phytochemicals Berberine and resveratrol and non-alcoholic fatty liver disease (NAFLD)
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Bernerine is a phytochemical found abundantly in root, bark, stem in plants of Berberis, including Oregon grape, barberry, tree turmeric, etc.
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc.
Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.
Sadly to say, Non alcoholic liver diseases has become most prevalence incidence to cause liver diseases because of uncontrolled diet with high in saturated fat. Conventional medication such as ameliorate, a cholesterol absorption inhibitor, is found to be effective in decreasing cholesterol absorption in the small intestine and ameliorated non-alcoholic fatty liver disease (NAFLD) pathology but with many side effects.
In herbal medicine, certain herbs have found to be effective not only in reducing the symptoms of non alcoholic, but also prevent the abnormal alanine aminotransferase functions and fat accumulation in liver.
Berberine and resveratrol, the phytochemical found abundantly in many vegetables and fruits as well herbs and herbal formulae such as Polygonum hypoleucum Ohwi, and Artemisia sacrorum Ledeb., and formulae including Yinchenhao Decoction (, YCHD), Qushi Huayu Decoction (, QSHYD), and Danning Tablet, were found not only to improve biochemical and histological change in nonalcoholic fatty liver disease, but also associated with inhibiting lipid accumulation through adenosine monophosphate-activated protein kinase activation or up regulating low-density lipoprotein receptor (LDLR) expression, alleviating lipid peroxidation, and reducing the production of inflammatory cytokines. In such instance, Berberine and resveratrol, may be considered as a potential treatment for nonalcoholic fatty liver disease in the future.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Non-alcoholic fatty liver disease and liver transplantation: Outcomes and advances by Said A.(PubMed)
(2) The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial by Takeshita Y, Takamura T, Honda M, Kita Y, Zen Y, Kato KI, Misu H, Ota T, Nakamura M, Yamada K, Sunagozaka H, Arai K, Yamashita T, Mizukoshi E, Kaneko S.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.
You can calculate your BMI index BMI= weight (kg)/ height (m2)
Bernerine is a phytochemical found abundantly in root, bark, stem in plants of Berberis, including Oregon grape, barberry, tree turmeric, etc.
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc.
Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.
Sadly to say, Non alcoholic liver diseases has become most prevalence incidence to cause liver diseases because of uncontrolled diet with high in saturated fat. Conventional medication such as ameliorate, a cholesterol absorption inhibitor, is found to be effective in decreasing cholesterol absorption in the small intestine and ameliorated non-alcoholic fatty liver disease (NAFLD) pathology but with many side effects.
In herbal medicine, certain herbs have found to be effective not only in reducing the symptoms of non alcoholic, but also prevent the abnormal alanine aminotransferase functions and fat accumulation in liver.
Berberine and resveratrol, the phytochemical found abundantly in many vegetables and fruits as well herbs and herbal formulae such as Polygonum hypoleucum Ohwi, and Artemisia sacrorum Ledeb., and formulae including Yinchenhao Decoction (, YCHD), Qushi Huayu Decoction (, QSHYD), and Danning Tablet, were found not only to improve biochemical and histological change in nonalcoholic fatty liver disease, but also associated with inhibiting lipid accumulation through adenosine monophosphate-activated protein kinase activation or up regulating low-density lipoprotein receptor (LDLR) expression, alleviating lipid peroxidation, and reducing the production of inflammatory cytokines. In such instance, Berberine and resveratrol, may be considered as a potential treatment for nonalcoholic fatty liver disease in the future.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
References
(1) Non-alcoholic fatty liver disease and liver transplantation: Outcomes and advances by Said A.(PubMed)
(2) The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial by Takeshita Y, Takamura T, Honda M, Kita Y, Zen Y, Kato KI, Misu H, Ota T, Nakamura M, Yamada K, Sunagozaka H, Arai K, Yamashita T, Mizukoshi E, Kaneko S.(PubMed)
Most Common Diseases of 50plus: Diabetes(The Recipes) --- A mayonnaise like dressing
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
If you are diabetic, the chance that you are overweight and this increase the
chance of high cholesterol and high blood pressure. So, to control the
glucose in your blood stream, you might want to try high protein diet
together with fighting cholesterol and high blood pressure natural remedies.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and
cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The recipe of A mayonnaise like dressing
Recipe contributed by Delicious dishes for diabetes by Robin Ellis, Published by Skyhorse publishing. Inc. You can view its website at www.skyhorsepublishing.com
Not as soft and unctuous of course, but good with salmon, for instance, and asparagus, and does not involve the irksome though rewarding business of making mayonnaise! Heresy, I know...
1 tbsp cinder vinegar
1 tsp Dijon mustard
juice of 1/4 of a lemon
4-5 tbsp extra-virgin canola/ colza oil
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
If you are diabetic, the chance that you are overweight and this increase the
chance of high cholesterol and high blood pressure. So, to control the
glucose in your blood stream, you might want to try high protein diet
together with fighting cholesterol and high blood pressure natural remedies.
Diabetes is defined as a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and
cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
The recipe of A mayonnaise like dressing
Recipe contributed by Delicious dishes for diabetes by Robin Ellis, Published by Skyhorse publishing. Inc. You can view its website at www.skyhorsepublishing.com
Not as soft and unctuous of course, but good with salmon, for instance, and asparagus, and does not involve the irksome though rewarding business of making mayonnaise! Heresy, I know...
1 tbsp cinder vinegar
1 tsp Dijon mustard
juice of 1/4 of a lemon
4-5 tbsp extra-virgin canola/ colza oil
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Most common Diseases Free and Longevity of 50 plus - Grape Seeds and Skins Part C By Foods to prevent and treat diseases
Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Over the years of research, 4 foods appeared mostly in medical studies in preventing and treating diseases, are Green Tea, Grape seed and skin, Turmeric and Organic Soy(Not for Western Women). All Right Reserved.
II. Grape Seeds and Skins
Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
C. By Foods to prevent and treat diseases
1. Acne
Grapes Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape. Dr. Fabbrocini G,and the scientists at the University of Naples Federico in the study of resveratrol-containing hydrogel administered to 20 patients affected by acne vulgaris enrolled in this single-blind study, showed a 53.75% mean reduction in the GAGS score on the resveratrol-treated sides of the face compared with 6.10% on the vehicle-treated sides of the face. These data were supported by histologic analysis, which showed a 66.7% mean reduction in the average area of microcomedones on the resveratrol-treated sides of the face. The comparison with the vehicle-treated side of the face (9.7% reduction) showed a clinically relevant and statistically significant decrease of lesions in areas treated with resveratrol-containing hydrogel(1).
2. Anxiety
In the study to determine the effect of resveratrol on hippocampal damage and behavioral deficits in 7-day-old rat pups subjected to contusion injury, showed that treatment with resveratrol decreased anxiety and increased cortex/hippocampus dependent memory of animals subjected to blunt head trauma. These results show that acute treatment of resveratrol has a neuroprotective role against trauma induced hippocampal neuron loss and associated cognitive impairment in rats(2).
3. Alzheimer's disease
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc. In the investigation of the neuroprotective properties of resveratrol found that Resveratrol has neuroprotective features both in vitro and in vivo in models of Alzheimer's disease (AD), but it has proved to be beneficial also in ischemic stroke, Parkinson's disease, Huntington's disease, and epilepsy, according to "Neuroprotective properties of resveratrolin different neurodegenerative disorders" by Albani D, Polito L, Signorini A, Forloni G.(3). Others, in the elucidation of the neuroprotective effect and influence of resveratrol on the extracellular levels of neurotransmitter and neuromodulator during ischemia/reperfusion in rats, found that chronic treatment with resveratrolremarkably reduced the release of excitatory neurotransmitter glutamate, aspartate and neuromodulator d-Serine during ischemia and reperfusion; and significantly increased the basal extracellular levels of inhibitory neurotransmitter gamma-amino-n-butyric acid, glycine and taurine. Chronic treatment with resveratrol also ameliorated O-phosphoethanolamine levels and excitotoxic index during ischemia and reperfusio, according to "Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats" by Li C, Yan Z, Yang J, Chen H, Li H, Jiang Y, Zhang Z(3)
4. Rheumatoid Arthritis (RA)
Resveratrol found abundantly in red wine and the skin and seed of grape is said to have an anti RA effect. In the study of Effects of resveratrol in inflammatoryarthritis, showed that according to control group in the resveratrol group, significantly decreased cartilage destruction was determined by H&E staining (p = 0.04). Loss of matrix proteoglycan content in the cartilage was much lower, as determined by safranin O staining (p = 0.03). We also observed marked synovial inflammation after intra-articular injection to control knees, but not in the resveratrol treated group knees (p = 0.01)(4).
5. Polymalagia Arthritis(PMR)
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
a. Immune system
a. 1. In the investigation of the immunomodulatory effects of decaffeinated greentea extract in rain bow of the study of "Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss)" by Sheikhzadeh N, Nofouzi K, Delazar A, Oushani AK.(32), researchers found that showed that decaffeinated green tea in lower doses of administration could be optimum to enhance the immunity of rainbow trout(5).
a.2. In the investigation of Green tea and Arthritis of the study of "Green teapolyphenol epigallocatechin 3-gallate in arthritis" by Ahmed S., researcher indicated that although these findings provide scientific evidence of the anti-rheumatic activity of EGCG, further preclinical studies are warranted before phase clinical trials could be initiated with confidence for patients with joint diseases(6).
6. Cataracts
In the study to evaluate the potential role that FoxO transcription factors play in modulating resveratrol's protective effects against oxidative stress in lens epithelial cells, showed that RES exerts a protective effect against oxidative damage in LEC cultures. The levels of expression of FoxO1A, FoxO3A, and FoxO4 appear to play a central role in determining the pro- or anti-apoptotic effects of RES. This has implications for future studies on oxidative stress-related lenticular disorders such as cataract formation(7).
7. Chronic obstructive pulmonary disease (COPD)
In the study to investigate the effect of dexamethasone versus resveratrol on the release of COPD-related inflammatory mediators (IL-6, IL-8, GM-CSF and MCP-1) and matrix-metalloprotease-9 (MMP-9) from alveolar macrophages exposed to gram-negative bacterial endotoxin (lipopolysaccharide, LPS), found that resveratrol almost completely reduced the release of all cytokines and MMP-9 without significant differences between the cohorts. Our data provide evidence for a corticosteroid resistance of alveolar macrophage-dependent inflammatory responses induced by gram-negative bacteria in COPD and thus question the utility of corticosteroids in COPD therapy. Instead, resveratrol may prove an alternative(8).
8. Chronic fatigue syndrome (CFS)
Resveratrol is a photochemical found abundantly in skin and seeds of grape. In the study of a chronic fatigue murine model by six repeated injections of Brucella abortus antigen to mice, which was manifested as reduced daily running activity and hippocampal atrophy, showed that resveratrol may be effective for improvingfatigue symptoms and enlarging the atrophic hippocampus by repressing apoptosis and promoting neurogenesis(9).
10. Autoimmune diseases
Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and TNF. Compared the flavonoid quercetin (Que) and cromolyn on cultured human mast cells. Que and cromolyn (100 µM) can effectively inhibit secretion of histamine and PGD(2). Que and cromolyn also inhibit histamine, leukotrienes and PGD(2) from primary human cord blood-derived cultured mast cells (hCBMCs) stimulated by IgE/Anti-IgE. However, Que is more effective than cromolyn in inhibiting IL-8 and TNF release from LAD2 mast cells stimulated by SP. Moreover, Que reduces IL-6 release from hCBMCs in a dose-dependent manner. Que inhibits cytosolic calcium level increase and NF-kappa B activation. Interestingly, Que is effective prophylactically, while cromolyn must be added together with the trigger or it rapidly loses its effect(10).
11. Candidiasis
In the study to investigate the antifungal action by resveratrol in Candida albicans, which is a human infectious fungi as an agent of candidiasis, showed that A significant accumulation of intracellular trehalose was induced by stress responses to resveratrol action, and a remarkable arrest of cell-cycle processes at the S-phase in C. albicans occured. Therefore, the fungicidal effects of resveratrol demonstrate that this compound is a potential candidate as an antifungal agent in treating infectious diseases by candidal infections(11).
12. Crohn's disease
in the study to examine the response to resveratrol by cultured smooth muscle cells isolated from colons of untreated Lewis rats, found that resveratrol decreases intestinal smooth muscle cell numbers through its effects on cell cycle arrest and apoptosis and also decreases collagen synthesis by the cells. These effects could be useful in preventing the smooth muscle cell hyperplasia and collagen deposition that characterize stricture formation in Crohn's disease(12).
13. Endometriosis
In the study to investigate the effects of resveratrol on human endometriotic implants in a nude mouse model and to examine its impact on human endometrial stromal (HES) cell invasiveness in vitro, found that resveratrol decreased the number of endometrial implants per mouse by 60% (P < 0.001) and the total volume of lesions per mouse by 80% (P < 0.001). Resveratrol (10-30 μM) also induced a concentration-dependent reduction of invasiveness of HES by up to 78% (P < 0.0001). Resveratrol inhibits development of endometriosis in the nude mouse and reduces invasiveness of HES cells. These observations may aid in the development of novel treatments of endometriosis(13).
14. Flu (influenza)
In the study of assayed the bioactivity of resveratrol as antiproliferative and antiviral drug in cultured fibroblasts. Studies by other Authors showed that this natural compound inhibits the proliferation of different viruses such as herpes simplex, varicella-zoster and influenza A. Resveratrol can effectively inhibit the synthesis of polyomavirus DNA. A possible interpretation is that, due to the damage caused by resveratrol to the plasma membrane, the transfer of the virus from the endoplasmic reticulum to the nucleus, may be hindered thus inhibiting the production of viral DNA(14).
15. Hepatitis
Resveratrol (RES), a well-known antioxidant and anti-inflammatory compound is associated of reduced risk of chronic liver diseases, researchers at the Ohio Universities Colleges of Medicine and Pharmacy indicated that enhancement of the dissolution of RES through a nanoparticle engineering process can result in increased hepatoprotective effects mediated by antioxidant and anti-inflammatory activities. Consequently, we suggest that RESN deserves further study, perhaps in prophylaxis of chronic liver diseases(15).
16. Human immunodeficiency virus (HIV)
In the study of Resveratrol is a polyphenolic plant-derived antioxidant abundantly found in certain grapes, roots, berries, peanuts and red wine, indicated that using primary human cardiomyocytes, evaluated the effects of AZT and pre-treatment with resveratrol on mitochondrial ROS generation and the cell death pathways. AZT induced concentration-dependent cell death, involving both caspase-3 and -7 and poly(ADP-ribose) polymerase activation, coupled with increased mitochondrial ROS generation in human cardiomyocytes(16).
17. Genital herpes
Resveratrol, a phytochemicals found in skin and seed of grape and red wineesveratrol (i) suppresses HSV induced activation of NF-kappaB within the nucleus and (ii) impairs expression of essential immediate-early, early and late HSV genes and synthesis of viral DNA(17).
18. Liver disease
Resveratrol is a plant-derived polyphenol that has a potential as a food source to extend lifespan and healthspan in model organism. In the study of the effect of resveratrol on mTOR signalingshowed that
resveratrol is an inhibitor of global protein synthesis, and that this effect is mediated through modulation of mTOR-dependent and independent signaling(18)
19. Multiple Sclerosis
In the study to investigate whether polyphenols modulate the expression and activity of the enzymes gelatinases A (MMP-2) and B (MMP-9), involved in the pathogenesis of multiple sclerosis (MS),
indicate that the flavonoids and non-flavonoids (flavonoids quercetin (QRC) and cathechins [green tea extract (GTE)] and the non-flavonoids resveratrol (RSV)and tyrosol/hydroxytyrosol (Oliplus)) tested exert their inhibitory effect on MMPs, displaying different mechanisms of action, possibly related to their structure. Therefore, their combined use may represent a powerful tool for the down-regulation of MMPs in the course of MS(19).
20. Osteoporosis
In the study to investigate the molecular mechanism of how resveratrol can modulate the lineage commitment of human mesenchymal stem cells to osteogenesis other than adipogenesis, showed that
resveratrol promoted spontaneous osteogenesis but prevented adipogenesis in human embryonic stem cell-derived mesenchymal progenitors. Resveratrol upregulated the expression of osteo-lineage genes RUNX2 and osteocalcin while suppressing adipo-lineage genes PPARγ2 and LEPTIN in adipogenic medium. Furthermore, the osteogenic effect of resveratrol was mediated mainly through SIRT1/FOXO3A with a smaller contribution from the estrogenic pathway(20).
21. Parkinson's disease
In the study to investigate the neuroprotective effects of resveratrol on 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease in rats. 6-OHDA-inducedParkinson's disease rat model involves chronic inflammation, mitochondrial dysfunction, and oxidative stress, and the loss of the dopaminergic neurons in the substantia nigra is the predominant lesion, found that resveratrol treatment also significantly decreased the levels of COX-2 and TNF-alpha mRNA in the substantia nigra as detected by real-time RT-PCR. COX-2 protein expression in the substantia nigra was also decreased as evidenced by Western blotting. These results demonstrate that resveratrol exerts a neuroprotective effect on 6-OHDA-induced Parkinson's disease rat model, and this protection is related to the reduced inflammatory reaction(21).
22. Pelvic inflammatory disease
Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases review provides an up-to-date discussion on recent advances regarding anti-inflammatory effects of resveratrol, mechanisms of action, and its potential for therapeutic use(22).
23. Thyroid disorders
In the study of resveratrol, the main ingredient found in skin and seed of grape and its impact on aging and thyroid function, showed that resveratrol is believed to regulate several biological processes, mainly metabolism and aging, by modulating the mammalian silent information regulator 1 (SIRT1) of the sirtuin family. Resveratrol may arrest, among various tumors, cell growth in both papillary and follicular thyroid cancer by activation of the mitogen-activated protein kinase (MAPK) signal transduction pathway as well as increase of p53 and its phosphorylation. Finally, resveratrol also influences thyroid function by enhancing iodide trapping and, by increasing TSH secretion via activation of sirtuins and the phosphatidylinositol- 4-phosphate 5 kinase γ (PIP5Kγ) pathway, positively affects metabolism(23)
24. Etc.
Side Effects
1. Overdose may cause headache, itchy scalp, dizziness, and nausea, abdominal pain etc.
2. Do not take the herbs if you have high blood pressure
3. Grape seed extract may interact with other medication, such blood thinner, NSAID painkiller, etc.
4. Do not take the herb in children or if you are pregnant without approval of the related field specialist.
5. etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=grapes%20and%20acne
(2) http://www.ncbi.nlm.nih.gov/pubmed/20108732
(3) http://www.ncbi.nlm.nih.gov/pubmed/20848560
(4) http://www.ncbi.nlm.nih.gov/pubmed/17115116
(5) http://www.ncbi.nlm.nih.gov/pubmed/21985858
(6) http://www.ncbi.nlm.nih.gov/pubmed/20447316
(7) http://www.ncbi.nlm.nih.gov/pubmed/21345980
(8) http://www.ncbi.nlm.nih.gov/pubmed/21447053
(9) http://www.ncbi.nlm.nih.gov/pubmed/21372384
(10) http://www.ncbi.nlm.nih.gov/pubmed/22470478
(11) http://www.ncbi.nlm.nih.gov/pubmed/18051601
(12) http://www.ncbi.nlm.nih.gov/pubmed/22052016
(13) http://www.ncbi.nlm.nih.gov/pubmed/20844278
(14) http://www.ncbi.nlm.nih.gov/pubmed/19570215
(15) http://www.ncbi.nlm.nih.gov/pubmed/19910122
(16) http://www.ncbi.nlm.nih.gov/pubmed/21461578
(17) http://www.ncbi.nlm.nih.gov/pubmed?term=turmeric%20herpes%20simplex%20virus
(18) http://www.ncbi.nlm.nih.gov/pubmed/22242130
(19) http://www.ncbi.nlm.nih.gov/pubmed/21207142
(20) http://www.ncbi.nlm.nih.gov/pubmed/21713995
(21) http://www.ncbi.nlm.nih.gov/pubmed/18940189
(22) http://www.ncbi.nlm.nih.gov/pubmed/22587021
(23) http://www.ncbi.nlm.nih.gov/pubmed/21946130
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
II. Grape Seeds and Skins
Grape is a woody vines of the genus Vitis, belong to the family Vitaceae, native to southern Turkey.
C. By Foods to prevent and treat diseases
1. Acne
Grapes Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape. Dr. Fabbrocini G,and the scientists at the University of Naples Federico in the study of resveratrol-containing hydrogel administered to 20 patients affected by acne vulgaris enrolled in this single-blind study, showed a 53.75% mean reduction in the GAGS score on the resveratrol-treated sides of the face compared with 6.10% on the vehicle-treated sides of the face. These data were supported by histologic analysis, which showed a 66.7% mean reduction in the average area of microcomedones on the resveratrol-treated sides of the face. The comparison with the vehicle-treated side of the face (9.7% reduction) showed a clinically relevant and statistically significant decrease of lesions in areas treated with resveratrol-containing hydrogel(1).
2. Anxiety
In the study to determine the effect of resveratrol on hippocampal damage and behavioral deficits in 7-day-old rat pups subjected to contusion injury, showed that treatment with resveratrol decreased anxiety and increased cortex/hippocampus dependent memory of animals subjected to blunt head trauma. These results show that acute treatment of resveratrol has a neuroprotective role against trauma induced hippocampal neuron loss and associated cognitive impairment in rats(2).
3. Alzheimer's disease
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc. In the investigation of the neuroprotective properties of resveratrol found that Resveratrol has neuroprotective features both in vitro and in vivo in models of Alzheimer's disease (AD), but it has proved to be beneficial also in ischemic stroke, Parkinson's disease, Huntington's disease, and epilepsy, according to "Neuroprotective properties of resveratrolin different neurodegenerative disorders" by Albani D, Polito L, Signorini A, Forloni G.(3). Others, in the elucidation of the neuroprotective effect and influence of resveratrol on the extracellular levels of neurotransmitter and neuromodulator during ischemia/reperfusion in rats, found that chronic treatment with resveratrolremarkably reduced the release of excitatory neurotransmitter glutamate, aspartate and neuromodulator d-Serine during ischemia and reperfusion; and significantly increased the basal extracellular levels of inhibitory neurotransmitter gamma-amino-n-butyric acid, glycine and taurine. Chronic treatment with resveratrol also ameliorated O-phosphoethanolamine levels and excitotoxic index during ischemia and reperfusio, according to "Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats" by Li C, Yan Z, Yang J, Chen H, Li H, Jiang Y, Zhang Z(3)
4. Rheumatoid Arthritis (RA)
Resveratrol found abundantly in red wine and the skin and seed of grape is said to have an anti RA effect. In the study of Effects of resveratrol in inflammatoryarthritis, showed that according to control group in the resveratrol group, significantly decreased cartilage destruction was determined by H&E staining (p = 0.04). Loss of matrix proteoglycan content in the cartilage was much lower, as determined by safranin O staining (p = 0.03). We also observed marked synovial inflammation after intra-articular injection to control knees, but not in the resveratrol treated group knees (p = 0.01)(4).
5. Polymalagia Arthritis(PMR)
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
a. Immune system
a. 1. In the investigation of the immunomodulatory effects of decaffeinated greentea extract in rain bow of the study of "Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss)" by Sheikhzadeh N, Nofouzi K, Delazar A, Oushani AK.(32), researchers found that showed that decaffeinated green tea in lower doses of administration could be optimum to enhance the immunity of rainbow trout(5).
a.2. In the investigation of Green tea and Arthritis of the study of "Green teapolyphenol epigallocatechin 3-gallate in arthritis" by Ahmed S., researcher indicated that although these findings provide scientific evidence of the anti-rheumatic activity of EGCG, further preclinical studies are warranted before phase clinical trials could be initiated with confidence for patients with joint diseases(6).
6. Cataracts
In the study to evaluate the potential role that FoxO transcription factors play in modulating resveratrol's protective effects against oxidative stress in lens epithelial cells, showed that RES exerts a protective effect against oxidative damage in LEC cultures. The levels of expression of FoxO1A, FoxO3A, and FoxO4 appear to play a central role in determining the pro- or anti-apoptotic effects of RES. This has implications for future studies on oxidative stress-related lenticular disorders such as cataract formation(7).
7. Chronic obstructive pulmonary disease (COPD)
In the study to investigate the effect of dexamethasone versus resveratrol on the release of COPD-related inflammatory mediators (IL-6, IL-8, GM-CSF and MCP-1) and matrix-metalloprotease-9 (MMP-9) from alveolar macrophages exposed to gram-negative bacterial endotoxin (lipopolysaccharide, LPS), found that resveratrol almost completely reduced the release of all cytokines and MMP-9 without significant differences between the cohorts. Our data provide evidence for a corticosteroid resistance of alveolar macrophage-dependent inflammatory responses induced by gram-negative bacteria in COPD and thus question the utility of corticosteroids in COPD therapy. Instead, resveratrol may prove an alternative(8).
8. Chronic fatigue syndrome (CFS)
Resveratrol is a photochemical found abundantly in skin and seeds of grape. In the study of a chronic fatigue murine model by six repeated injections of Brucella abortus antigen to mice, which was manifested as reduced daily running activity and hippocampal atrophy, showed that resveratrol may be effective for improvingfatigue symptoms and enlarging the atrophic hippocampus by repressing apoptosis and promoting neurogenesis(9).
10. Autoimmune diseases
Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and TNF. Compared the flavonoid quercetin (Que) and cromolyn on cultured human mast cells. Que and cromolyn (100 µM) can effectively inhibit secretion of histamine and PGD(2). Que and cromolyn also inhibit histamine, leukotrienes and PGD(2) from primary human cord blood-derived cultured mast cells (hCBMCs) stimulated by IgE/Anti-IgE. However, Que is more effective than cromolyn in inhibiting IL-8 and TNF release from LAD2 mast cells stimulated by SP. Moreover, Que reduces IL-6 release from hCBMCs in a dose-dependent manner. Que inhibits cytosolic calcium level increase and NF-kappa B activation. Interestingly, Que is effective prophylactically, while cromolyn must be added together with the trigger or it rapidly loses its effect(10).
11. Candidiasis
In the study to investigate the antifungal action by resveratrol in Candida albicans, which is a human infectious fungi as an agent of candidiasis, showed that A significant accumulation of intracellular trehalose was induced by stress responses to resveratrol action, and a remarkable arrest of cell-cycle processes at the S-phase in C. albicans occured. Therefore, the fungicidal effects of resveratrol demonstrate that this compound is a potential candidate as an antifungal agent in treating infectious diseases by candidal infections(11).
12. Crohn's disease
in the study to examine the response to resveratrol by cultured smooth muscle cells isolated from colons of untreated Lewis rats, found that resveratrol decreases intestinal smooth muscle cell numbers through its effects on cell cycle arrest and apoptosis and also decreases collagen synthesis by the cells. These effects could be useful in preventing the smooth muscle cell hyperplasia and collagen deposition that characterize stricture formation in Crohn's disease(12).
13. Endometriosis
In the study to investigate the effects of resveratrol on human endometriotic implants in a nude mouse model and to examine its impact on human endometrial stromal (HES) cell invasiveness in vitro, found that resveratrol decreased the number of endometrial implants per mouse by 60% (P < 0.001) and the total volume of lesions per mouse by 80% (P < 0.001). Resveratrol (10-30 μM) also induced a concentration-dependent reduction of invasiveness of HES by up to 78% (P < 0.0001). Resveratrol inhibits development of endometriosis in the nude mouse and reduces invasiveness of HES cells. These observations may aid in the development of novel treatments of endometriosis(13).
14. Flu (influenza)
In the study of assayed the bioactivity of resveratrol as antiproliferative and antiviral drug in cultured fibroblasts. Studies by other Authors showed that this natural compound inhibits the proliferation of different viruses such as herpes simplex, varicella-zoster and influenza A. Resveratrol can effectively inhibit the synthesis of polyomavirus DNA. A possible interpretation is that, due to the damage caused by resveratrol to the plasma membrane, the transfer of the virus from the endoplasmic reticulum to the nucleus, may be hindered thus inhibiting the production of viral DNA(14).
15. Hepatitis
Resveratrol (RES), a well-known antioxidant and anti-inflammatory compound is associated of reduced risk of chronic liver diseases, researchers at the Ohio Universities Colleges of Medicine and Pharmacy indicated that enhancement of the dissolution of RES through a nanoparticle engineering process can result in increased hepatoprotective effects mediated by antioxidant and anti-inflammatory activities. Consequently, we suggest that RESN deserves further study, perhaps in prophylaxis of chronic liver diseases(15).
16. Human immunodeficiency virus (HIV)
In the study of Resveratrol is a polyphenolic plant-derived antioxidant abundantly found in certain grapes, roots, berries, peanuts and red wine, indicated that using primary human cardiomyocytes, evaluated the effects of AZT and pre-treatment with resveratrol on mitochondrial ROS generation and the cell death pathways. AZT induced concentration-dependent cell death, involving both caspase-3 and -7 and poly(ADP-ribose) polymerase activation, coupled with increased mitochondrial ROS generation in human cardiomyocytes(16).
17. Genital herpes
Resveratrol, a phytochemicals found in skin and seed of grape and red wineesveratrol (i) suppresses HSV induced activation of NF-kappaB within the nucleus and (ii) impairs expression of essential immediate-early, early and late HSV genes and synthesis of viral DNA(17).
18. Liver disease
Resveratrol is a plant-derived polyphenol that has a potential as a food source to extend lifespan and healthspan in model organism. In the study of the effect of resveratrol on mTOR signalingshowed that
resveratrol is an inhibitor of global protein synthesis, and that this effect is mediated through modulation of mTOR-dependent and independent signaling(18)
19. Multiple Sclerosis
In the study to investigate whether polyphenols modulate the expression and activity of the enzymes gelatinases A (MMP-2) and B (MMP-9), involved in the pathogenesis of multiple sclerosis (MS),
indicate that the flavonoids and non-flavonoids (flavonoids quercetin (QRC) and cathechins [green tea extract (GTE)] and the non-flavonoids resveratrol (RSV)and tyrosol/hydroxytyrosol (Oliplus)) tested exert their inhibitory effect on MMPs, displaying different mechanisms of action, possibly related to their structure. Therefore, their combined use may represent a powerful tool for the down-regulation of MMPs in the course of MS(19).
20. Osteoporosis
In the study to investigate the molecular mechanism of how resveratrol can modulate the lineage commitment of human mesenchymal stem cells to osteogenesis other than adipogenesis, showed that
resveratrol promoted spontaneous osteogenesis but prevented adipogenesis in human embryonic stem cell-derived mesenchymal progenitors. Resveratrol upregulated the expression of osteo-lineage genes RUNX2 and osteocalcin while suppressing adipo-lineage genes PPARγ2 and LEPTIN in adipogenic medium. Furthermore, the osteogenic effect of resveratrol was mediated mainly through SIRT1/FOXO3A with a smaller contribution from the estrogenic pathway(20).
21. Parkinson's disease
In the study to investigate the neuroprotective effects of resveratrol on 6-hydroxydopamine (6-OHDA)-induced Parkinson's disease in rats. 6-OHDA-inducedParkinson's disease rat model involves chronic inflammation, mitochondrial dysfunction, and oxidative stress, and the loss of the dopaminergic neurons in the substantia nigra is the predominant lesion, found that resveratrol treatment also significantly decreased the levels of COX-2 and TNF-alpha mRNA in the substantia nigra as detected by real-time RT-PCR. COX-2 protein expression in the substantia nigra was also decreased as evidenced by Western blotting. These results demonstrate that resveratrol exerts a neuroprotective effect on 6-OHDA-induced Parkinson's disease rat model, and this protection is related to the reduced inflammatory reaction(21).
22. Pelvic inflammatory disease
Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases review provides an up-to-date discussion on recent advances regarding anti-inflammatory effects of resveratrol, mechanisms of action, and its potential for therapeutic use(22).
23. Thyroid disorders
In the study of resveratrol, the main ingredient found in skin and seed of grape and its impact on aging and thyroid function, showed that resveratrol is believed to regulate several biological processes, mainly metabolism and aging, by modulating the mammalian silent information regulator 1 (SIRT1) of the sirtuin family. Resveratrol may arrest, among various tumors, cell growth in both papillary and follicular thyroid cancer by activation of the mitogen-activated protein kinase (MAPK) signal transduction pathway as well as increase of p53 and its phosphorylation. Finally, resveratrol also influences thyroid function by enhancing iodide trapping and, by increasing TSH secretion via activation of sirtuins and the phosphatidylinositol- 4-phosphate 5 kinase γ (PIP5Kγ) pathway, positively affects metabolism(23)
24. Etc.
Side Effects
1. Overdose may cause headache, itchy scalp, dizziness, and nausea, abdominal pain etc.
2. Do not take the herbs if you have high blood pressure
3. Grape seed extract may interact with other medication, such blood thinner, NSAID painkiller, etc.
4. Do not take the herb in children or if you are pregnant without approval of the related field specialist.
5. etc.
Chinese Food Therapy
The Best Way to prevent, treat your disease, including Obesity
and restore your health naturally with Chinese diet
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed?term=grapes%20and%20acne
(2) http://www.ncbi.nlm.nih.gov/pubmed/20108732
(3) http://www.ncbi.nlm.nih.gov/pubmed/20848560
(4) http://www.ncbi.nlm.nih.gov/pubmed/17115116
(5) http://www.ncbi.nlm.nih.gov/pubmed/21985858
(6) http://www.ncbi.nlm.nih.gov/pubmed/20447316
(7) http://www.ncbi.nlm.nih.gov/pubmed/21345980
(8) http://www.ncbi.nlm.nih.gov/pubmed/21447053
(9) http://www.ncbi.nlm.nih.gov/pubmed/21372384
(10) http://www.ncbi.nlm.nih.gov/pubmed/22470478
(11) http://www.ncbi.nlm.nih.gov/pubmed/18051601
(12) http://www.ncbi.nlm.nih.gov/pubmed/22052016
(13) http://www.ncbi.nlm.nih.gov/pubmed/20844278
(14) http://www.ncbi.nlm.nih.gov/pubmed/19570215
(15) http://www.ncbi.nlm.nih.gov/pubmed/19910122
(16) http://www.ncbi.nlm.nih.gov/pubmed/21461578
(17) http://www.ncbi.nlm.nih.gov/pubmed?term=turmeric%20herpes%20simplex%20virus
(18) http://www.ncbi.nlm.nih.gov/pubmed/22242130
(19) http://www.ncbi.nlm.nih.gov/pubmed/21207142
(20) http://www.ncbi.nlm.nih.gov/pubmed/21713995
(21) http://www.ncbi.nlm.nih.gov/pubmed/18940189
(22) http://www.ncbi.nlm.nih.gov/pubmed/22587021
(23) http://www.ncbi.nlm.nih.gov/pubmed/21946130
Subscribe to:
Posts (Atom)