Medical Advisor Journals

Wednesday, October 5, 2016

Herbal Therapy: The Aloe Vera effects on Colon cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.

Colon cancer

Colon Cancer is defined as a condition of the abnormal proliferation of cells in the colon.

The Ingredients
The main areas of chemical constituents of Aloe vera include: Aloe-Emodin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

The benefits
Aloe emodin (AE), found in Aloe vera has been suggested to have antiproliferative activity in various cancer cell lines in many studies. In the study of colon cancer, AE appreciably induced cell death specifically through the induction of apoptosis and by activating caspases 9/6, depending on caspase-
6. Other study on colon cancer also showed an efficacy of AE as it suppressed the nuclear translocation and DNA binding of NF-κB, which is an important transcription factor for controlling MMP-2/9 and VEGF gene expression.

Side effects
1. Butterbur may be liver-toxic to liver and cause cancer due to the presence of pyrrolizidine alkaloids(a)
2. If you are pregnant please do not use Butterbur with out the permission of the related special field specialist
3. Allergic effect to certain people who are allergic to ragweed, marigold, daisy, etc.
4. Overdoses may cause indigestion, headache, nausea, vomiting, diarrhea, etc.
5. Etc.

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Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

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References
(1) Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2) by Lin SY, Yang JH, Hsia TC, Lee JH, Chiu TH, Wei YH, Chung JG.(PubMed)
(2) Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells by Suboj P, Babykutty S, Srinivas P, Gopala S.(PubMed)
(3) Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB by Suboj P, Babykutty S, Valiyaparambil Gopi DR, Nair RS, Srinivas P, Gopala S.(PubMed)

Chinese Herbal Medicine Therapy: San Qi or Tian Qi (Radix Pseudoginseng)

San Qi or Tian Qi (Radix Pseudoginseng)

San Qi is also known as pseudoginseng root. The sweet, slight bitter and warm herb has been used in TCM as anticoagulation, Anti-inflammation, anti cancers and anti aging agent and to lower cholesterol, stop bleeding, improve capillary circulation, etc., as it eliminates Blood accumulation, stops bleeding, Moves Blood, calms pain, etc. by enhancing the functions of liver, stomach and large intestine channels.

Ingredients
1. Ginsenoside
2. Gamma-muurolene
3. Cyperene
4. Alpha-elemene
5. Gammma-cadinene
6. Delta-cadinene
7. Alpha-gurjunene
8. Alpha-guaiene
9. Alpha-copaene
10. Beta-cuabebene PN and EPGF can promote VEC proliferation, migration, DNA synthesis and VEGF mRNA expression. The results suggest that they have a certain effect on the genesis and development of new vessels in the ischemic myocardium.
11. Caryophyllene
12. Delta-guaiene
13. Alpha-cedrene
14. Etc.

Health Benefits
1. HUVEC proliferation and secretion of VEGF
In the study to evaluate the effects of Radix Ginseng and Radix Notoginseng formula on secretion of vascular endothelial growth factor (VEGF) and expression of vascular endothelial growth factor receptor-2 (VEGFR-2) in human umbilical vein endothelial cells (HUVECs) in vitro, indicated that Radix Ginseng and Radix Notoginseng formula can promote HUVEC proliferation and secretion of VEGF, as well as the expression of VEGFR-2 protein, which may be one of the mechanisms of Radix Ginseng and Radix Notoginseng formula in promoting angiogenesis(1).
2. Vascular endothelial cell proliferation and migration
In the study to investigate the effects of extracts from Panax notoginseng (EPN) and Panax ginseng fruit (EPGF) on the proliferation and migration of human umbilical vein endothelial cells (HUVECs) in vitro, showed that PN and EPGF can promote VEC proliferation, migration, DNA synthesis and VEGF mRNA expression. The results suggest that they have a certain effect on the genesis and development of new vessels in the ischemic myocardium(2).
3. Angiogenic effect
In the study to obser the angiogenic effects of PNS on human umbilical vein endothelial cells (HUVECs) in vitro and zebrafish in vivo, found that PNS can promote angiogenesis, and that the proangiogenic effects involve the VEGF-KDR/Flk-1 and PI3K-Akt-eNOS signaling pathways(3).
4. Renal interstitial fibrosis
In the study to investigate the effects of compound Radix Notoginseng (RN) on renal interstitial fibrosis and kidney-targeting treatment, the result indicated that RN and compound Radix Notoginseng (CRN) can inhibit UUO-induced renal interstitial fibrosis in rats, and CRN treatment is more effective than RN in reducing interstitial fibrosis(4).
5. Herpes simplex virus
In the study of Notoginsenoside ST-4 inhibits virus penetration of herpes simplex virus in vitro, researchers found that analyzed by attachment assay and penetration assay based on plaque reduction assay, the antiviral activity of notoginsenoside ST-4 was principally due to the penetration inhibition effects, which was confirmed by fluorescence microscopy observation that notoginsenoside ST-4 blocked the penetration of virus. Therefore, notoginsenoside ST-4 might be a promising agent for herpes simplex virus infection(5).
6. Ischemic stroke
With the aim to investigate the synergistic action of low dose of aspirin combined with sanchitongshu capsule in the treatment of patients with light and moderate ischemic stroke in acute and subacute stages, with participants assigned either to receive aspirin (50mg per day) and sanchitongshu capsule (200mg three times a day) or aspirin (50mg per day) and placebo capsule, showed that low dose of aspirin combined with sanchitongshu capsule significantly ameliorated neurological deficit (increased score of ESS: t=-5.02, p<0.0001) and activities of daily living (increased score of BI: t=-2.4, p=0.0178) after treatment compared with aspirin alone. Adverse reaction which occurred equally in both arms, was light to moderate and disappeared without special treatment. Sanchitongshu capsule, as a complementary medicine to aspirin, was effective in improving outcomes after ischemic stroke. It was a safe drug in our trial(6).
7. Etc.

Side Effects
1. the herb may cause allergic effects
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/20388479
(2) http://www.ncbi.nlm.nih.gov/pubmed/18568327
(3) http://www.ncbi.nlm.nih.gov/pubmed/19107746
(4) http://www.ncbi.nlm.nih.gov/pubmed/22455126
(5) http://www.ncbi.nlm.nih.gov/pubmed/21623512

Chinese Herbal Medicine Therapy: San Leng (Rhizoma Sparganii Stoloniferi)

San Leng (Rhizoma Sparganii Stoloniferi)

San Leng is also known as Burreed Rhizome. The acrid, bitter and neutral herb has been used in TCM to promote blood clots, inhibit thrombosis, lower the blood viscosity, etc. as it breaks up the Blood, eliminates Blood accumulation, moves Qi. calms pain, etc. by enhancing the functions of liver and spleen channels.

Ingredients
1. benzeneethanol
2. 1,4-benzenediol
3. Hexadecanoic acid
4. Dehydrocostuslactone
5. 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-4-one
6. 1-hydroxy-2-acetyl-4-methylbenzene
7. β-elemene
8. 2- furanmethanol
9. 2-acetylpyrrole
10. Etc.

Health Benefits
1. Antioxidant Activities
In an efficient ultrasound-assisted extraction technique was employed to extract total flavonoids from Sparganii rhizoma, indicate that the antioxidant activities of the purified flavonoids including DPPH radical scavenging activity, ABTS<sup>+</sup> radical scavenging activity, reducing power, hydroxyl radical scavenging activity and superoxide anion scavenging activity, were evaluated<em> in vitro</em>, which suggested that the flavonoids showed significant antioxidant activities. Rutin, kaempferol and formononetin were identified in the extract by comparing relative retention times and UV-Vis spectra with those of reference standards(1).
2. Anti-angiogenesis and anti-estrogen pharmacologic activities
In the studied Rhizoma Sparganii (RS) potential toxicity on reproduction in mice, indicated that he offspring of treated mice (100, 200 and 400 mg/kg RS extract) during their pregnancy had various pathological conditions, suggesting an abnormal fibroblast growth factor-(FGF) signaling phenomenon during pregnancy. Embryos from the 400 mg/kg group had significantly depressed levels of FGF-1 (P < 0.01) and VEGF (P < 0.05) expression levels as compared to controls by immunohistochemical test. Dysplasia in the heart (12.9%), craniofacial region (18.3%) and vertebrae (32.5%) presented in embryos of the 400 mg/kg group. Furthermore, the ER-α expression was inversely proportional to FGF-1 levels in the same embryo (P < 0.01) and concluded that these results implicate a FGF signaling abnormality in vivo and indicate that RS has anti-angiogenesis and anti-estrogen toxicity effects in pregnant rodents(2).
3. Primary dysmenorrhea of excess syndrome
In the study of patients with primary dysmenorrhea of excess syndrome were randomly divided into an application group and a medication group. The application group of 31 cases were treated with application of Chinese medicine composed of Zhinanxing (Rhizoma Arisaematis), Sanleng (Rhizoma Sparganii), Ezhu (Rhizoma Zedoariae), etc. at Zhongji (CV 3), Guanyuan (CV 4), Qihai (CV 6); and the medication group of 30 cases were treated with oral administration of Tianqi Tongjing Capsules, found that the total effective rate of 93.5% in the application group was significantly better than 73.3% in the medication group (P < 0.05); after treatment, the scores of the symptoms were significantly decreased in the two groups (both P < 0.01), with more obvious improvement in the application group than the medication group (P < 0.01). The PGE2 content was significantly increased, and the PGF2alpha content and PGF2alpha/PGE2 were significantly decreased in the application group (all P < 0.01)(3).
4. Hepatic cells
In the investigation of the effects of rhizoma sparganii and radices zedoariae on hepatic fibrosis, showed that Rhizoma sparganii and radices zedoariae can protect hepatic cells, alleviate degeneration and necrosis, recover structure and function, and reduce the proliferation of fibrous tissue(4).
5. Etc.
Side Effects
1. Do not use the herb in case of spleen deficiency without blood stasis
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22664466
(2) http://www.ncbi.nlm.nih.gov/pubmed/21878384
(3) http://www.ncbi.nlm.nih.gov/pubmed/19565730
(4) http://www.ncbi.nlm.nih.gov/pubmed/12776535

Tuesday, October 4, 2016

Chinese Herbal Medicine Therapy: Ru Xiang (Gummi Olibanum)

Rou Cong Rong (Herba Cistanches Deserticolae)

Ru Xiang is also known as Frankincense Carterii. The acrid, bitter and warm herb has been used in TCM to treat pain due to blood clots, spastic muscle, carbuncles, gum bleeding, gingivitis, rheumatoid arthritis, cirrhosis of liver, amenorrhea, etc., as it moves Blood, calms pain, solves oedema, romotes tissue regeneration, etc. by enhancing the functions of heart, liver and spleen channels.

Ingredients
1. Resin
2. Pinene, Dipentene
3. α Phellandrene
4. β Phellandrene
5. α-amyrone,
6. α-amyrinone
7. α-amyrin
8. β-amyrin
8. Viridiflorol
9. Insensole
10. Insensole oxide
11. Etc.

Health Benefits
1. Arthritis
In the random, blinded study, the anti-arthritic effects of a BC extract were observed and compared to vehicle control in a Lewis rat adjuvant arthritis model (n=8/group), showed that At 0.90 g/kg per day, BC significantly decreased arthritic scores between days 20 and 25 (p<0.05) and reduced paw edema on days 18, 20 and 22 compared to control (p<0.05). It also significantly suppressed local tissue TNF-alpha and IL-1beta (p<0.05). No major adverse effects were observed in animals during the repeated-dose treatment profile although mild fur discoloration was noted(1).
2. Persistent inflammation
In this randomized, blinded study, the antihyperalgesic and antiedema effects of 3 dosages of BC were compared to a vehicle control. Inflammation was induced in rats by injecting complete Freund’s adjuvant (CFA) into one hind paw, showed that BC produces significant antihyperalgesia and anti-inflammation effects and that the antihyperalgesia may be mediated by suppressed inflammation-induced Fos expression in the spinal dorsal horn neurons(2).
3. Antiproliferative and apoptotic activities
In the study to investigate the digallic acid (DGA) purified from Pistacia lentiscus. L fruits for its antiproliferative and apoptotic activities on human lymphoblastoid TK6 cells, showed that the inhibition of lymphoblastoid cell proliferation was noted from 8.5 mug/ml of DGA. The induction of apoptosis was confirmed by DNA fragmentation and PARP cleavage. We have demonstrated that DGA induces apoptosis by activating the caspase-8 extrinsic pathway. Caspase-3 was also activated in a dose dependent manner(3).
4. Anti-inflammatory activity
In the study of the topical anti-inflammatory activity of essential oil of Pistacia lentiscus L., using carrageenan induced rat paw edema and cotton pellet induced granuloma. indicated that on topical application, the oil exhibited a significant decrease in paw edema. The oil also inhibited cotton pellet-induced granuloma, and reduced serum TNF-alpha and IL-6. It can be concluded that the essential oil of Pistacia lentiscus reduces leukocyte migration to the damaged tissue and exhibits anti-inflammatory activity.
5. Etc.

Side Effects
1. Do not use the herb in case of spleen deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/15970410
(2) http://www.ncbi.nlm.nih.gov/pubmed/15865500
(3) http://www.ncbi.nlm.nih.gov/pubmed/22686580
(4) http://www.ncbi.nlm.nih.gov/pubmed/22164803

Chinese Herbal Medicine Therapy: Rou Gui (Cortex Cinnamomi Cassiae)

Rou Gui (Cortex Cinnamomi Cassiae)

Rou Gui or Gui Zhi is also known as cinnamon bark or cinnamon twig accordingly. The acrid, sweet and warm herbs (Rou Gui very warm herb) have been used in TCM to treat cold limbs, chill and fever, cold phlegm, diarrhea, muscle spasm, headache, back pain, sweating and promote urination, etc., as it tonifies Fire, benefits the Yan, disperses Cold, calms pain, promotes circulation in the channels, moves Blood, etc. by enhancing the functions of heart, lung and bladder channels.

Ingredients
1. Cinnamic aldehyde
2. Cinnamyl acetate
3. Eugenol
4. Aldehyde
5. Pinene
6. Coumarin
7. Cinnamyl alcohol
8. Cinnamic acid
9. Cinnzeylanol
10. Cinnzeylanine
11. Etc.

Health Benefits
1. Diabetes
In the investigation of the clinical potential of aqueous extract of cinnamon and it potential effects in diabetes found that high in type A polyphenols, have also demonstrated improvements in fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome, according to”Chromium and polyphenols from cinnamon improve insulin sensitivity” by Anderson RA.(1)
2. Immunomodulatory effect
In administration of popular herb used in traditional medicine to treat various disorders such as chronic gastric symptoms, arthritis, and the common cold and its immunomodulatory effect found that observations provided evidence that CWE was able to down-regulate IFN-γ expression in activated T cells without altering IL-2 production, involving inhibition of p38, JNK, ERK1/2, and STAT4, according to the study of “Immunomodulatory effect of water extract of cinnamon on anti-CD3-induced cytokine responses and p38, JNK, ERK1/2, and STAT4 activation” by Lee BJ, Kim YJ, Cho DH, Sohn NW, Kang H.(2)
3. Antimicrobial Activities
In the observation of three natural essential oils (i.e., clove bud oil, cinnamon oil, and star anise oil) and their antimicrobal effects found that the cinnamon oil-chitosan film had also better antimicrobial activity than the clove bud oil-chitosan film. The results also showed that the compatibility of cinnamon oil with chitosan in film formation was better than that of the clove bud oil with chitosan, according to the study of “Synergistic Antimicrobial Activities of Natural Essential Oils with Chitosan Films” by Wang L, Liu F, Jiang Y, Chai Z, Li P, Cheng Y, Jing H, Leng X.(3)
4. Anti-inflammatory activity
In the investigation of Myristicin (1-allyl-5-methoxy-3,4-methylenedioxybenzene) is an active aromatic compound found in nutmeg (the seed of Myristica fragrans), carrot, basil,cinnamon, and parsley and it anti-inflammatory effects found that Myristicin significantly inhibited the production of calcium, nitric oxide (NO),interleukin (IL)-6, IL-10, interferon inducible protein-10, monocyte chemotactic protein(MCP)-1, MCP-3, granulocyte-macrophage colony-stimulating factor, macrophage inflammatory protein (MIP)-1α, MIP-1β, and leukemia inhibitory factor in dsRNA[polyinosinic-polycytidylic acid]-induced RAW 264.7 cells (P < 0.05), according to the study of “Anti-inflammatory effect of myristicin on RAW 264.7 macrophages stimulated with polyinosinic-polycytidylic acid” by Lee JY, Park W.(4)
5. Cervical Cancer
In the evaluation of Eugenol, a potential chemopreventive agent, is a component of clove and several other spices such as basil, cinnamon, and bay leaves and its anti cancer effects found that eugenol exerts its anticancer activities via apoptosis induction and anti-inflammatory properties and also provide the first evidence demonstrating synergism between eugenol and gemcitabine, which may enhance the therapeutic index of prevention and/or treatment of cervical cancer, according to the study of “Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells” by Hussain A, Brahmbhatt K, Priyani A, Ahmed M, Rizvi TA, Sharma C.(5)
6. Menstrual pain
In the investigation of the alleviating effects of aromatherapy massage, including clary sage, marjoram, cinnamon, ginger, and geranium in a base of almond oil and acetaminophen on menstrual pain in Korean high school girls found that aromatherapy massage was found to be more highly associated with reduction in the level of menstrual pain than acetaminophen, according to the study of “Aromatherapy massage on the abdomen for alleviating menstrual pain in high school girls: a preliminary controlled clinical study” by Hur MH, Lee MS, Seong KY, Lee MK.(6)
7. Systolic Blood Pressure
In this study adult subjects 30 years of age or older with type 2 diabetes were randomized to treatment with 1,200 mg/day cinnamon found that Systolic blood pressure (SBP) declined from baseline values by 3.4±11.4 mm Hg in the cinnamon group, according to the study of “Dietary Cinnamon Supplementation and Changes in Systolic Blood Pressure in Subjects with Type 2 Diabetes” by Wainstein J, Stern N, Heller S, Boaz M.(7)
8. Anti biotic
In the investigation of cinnamaldehyde its effects in Campylobacter jejuni which is the leading cause of bacterial diarrheal illness worldwide found that Films with ≥1.5% cinnamaldehyde reduced populations of all strains to below detection at 23 °C at 72 h. At 4 °C with cinnamaldehyde, reductions were variable for all strains, ranging from 0.2 to 2.5 logs and 1.8 to 6.0 logs at 1.5% and 3.0%, according to the study of “Antimicrobial edible apple films inactivate antibiotic resistant and susceptible Campylobacter jejuni strains on chicken breast” by Mild RM, Joens LA, Friedman M, Olsen CW, McHugh TH, Law B, Ravishankar S.(8)
9. Anti-atherosclerotic activity
In the observation of Aqueous extracts of ground pepper, cinnamon, rosemary, ginger, and clove and their effects in pathogenesis of diabetic complications and atherosclerosis found that Hydrophilic ingredients of cinnamon and clove showed potent activities to suppress the incidence of atherosclerosis and diabetes via strong antioxidant potential, prevention of apoA-I glycation and LDL-phagocytosis, following a 5-week high cholesterol diet, according to the study of “Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish” by Jin S, Cho KH.(9)
10. Antihyperglycemic and antihyperlipidemic effects
In the investigation of of Cinnamomi Cassiae extract of Cinnamon and it effects in antihyperglycemic and antihyperlipidemic found that the fasting blood glucose and postprandial 2 h blood glucose levels in the cinnamon treated group were significantly lower than those in the control group (p < 0.01), whereas the serum insulin and adiponectin levels were significantly higher in the cinnamon treated group than in the control group (p < 0.05). The serum lipids and hepatic lipids were improved in the cinnamon administered group. Also the PPARalpha mRNA (liver) and PPARgamma mRNA (adipose tissue) expression levels were increased significantly in the cinnamon treated group (p < 0.05) in test mices, according to the study of “Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice” by Kim SH, Choung SY.(10)
11. Osteopenic disease
In the evaluation of Cinnamon zeylanicum and its effects in bone loss, including osteoporosis, bone metastasis, and rheumatoid arthritis found that cinnamaldehyde and 2-methoxycinnamaldehyde as active components reducing osteoclast-like cell formation and inhibiting NFATc1 expression. Notably, in a resorption pit assay, 2-methoxycinnamaldehyde exhibited remarkable inhibition rates of 95% at 2 microM on bone resorption and concluded that Cinnamon zeylanicum inhibits RANKL-induced osteoclastogenesis. This finding raises prospects for the development of a novel approach in the treatment of osteopenic disease, according to the study of “Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation” by Tsuji-Naito K.(11)
12. Cognitive impairment
In the examination of Orally administrated cinnamon extract and it effects in cognitive impairment found that oral administration of CEppt to an aggressive AD transgenic mice model led to marked decrease in 56 kDa Aβ oligomers, reduction of plaques and improvement in cognitive behavior, according to the study of “Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer’s disease animal model” byFrydman-Marom A, Levin A, Farfara D, Benromano T, Scherzer-Attali R, Peled S, Vassar R, Segal D, Gazit E, Frenkel D, Ovadia M.(12)
13. Etc.

Side Effects
1. Do not use the herbs in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
2. Cinnamaldehyde is toxic to liver
3. Do not use in case of liver fire ascending, warm-febrile diseases, Yin deficiency with heat, etc.
4. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Chinese herbal Medicine Therapy: Rou Dou Kou (Semen Myristicae Fragrantis)

Rou Dou Kou (Semen Myristicae Fragrantis)

Rou Dou Kou is also known as Nutmegs. The acrid, warm and toxic herb has been used in TCM to treat diarrhea, abdominal pain and flatulence, cold extremities, incontrollable diarrhea, lack of appetite and vomiting, weak digestion, vomiting and diarrhea, etc. as it warms the Middle Burner, moves Qi, stops incontinence of stools and anal ptosis due to chronic diarrhea, etc. by enhancing the functions of spleen, stomach and large intestine channels.

Ingredients
1. Pinene
2. Sabinene
3. Camphene
4. Myristicin
5. Eugenol¡
6. Safrol
7. Elemicin
8. Alpha-Thujene
9. Carene
10. Dipentene
11. Geraniol
12. Myristin
13.Olein
14. Etc.

Health Benefits
1. Mutagenic and antimutagenic effects
In the study to investigate the potential anticancer efficacy of the leaf extract of Myristica fragrans (Houtt.). Methanol leaf extract of M. fragrans (Houtt.) alone for mutagenicity in the bacterial reverse mutation (Ames) test, using the Salmonella typhimurium TA100 strain, the Allium cepa, found that Phytochemical compounds, possessing antioxidant activity, may be responsible for the observed effects, suggesting a strong antimutagenic activity of the MeOH leaf extract of M. fragrans, a necessary characteristic of a promising anticancer agent.(1).
2. Sexual function improving effect
In the study to evaluate the aphrodisiac effect of 50% ethanolic extract of nutmeg along with its likely adverse effects and acute toxicity using various animal models, showed that he resultant significant and sustained increase in the sexual activity of normal male rats without any conspicuous adverse effects indicates that the 50% ethanolic extract of nutmeg possesses aphrodisiac activity, increasing both libido and potency, which might be attributed to its nervous stimulating property. The present study thus provides a scientific rationale for the traditional use of nutmeg in the management of male sexual disorders(2).
3. Antibacterial activity
I the study to evaluate the antibacterial activity of Prasaprohyai formula and its components against pathogenic bacteria, showed the that Prasaprohyai formula and its components were able to inhibit the growth of both Gram positive and Gram negative bacteria including multiresistant strains. The volatile oil extracts seemed to play an important role in antimicrobial activities. The development of Prasaprohyai formula for alternative medicine will be approached in future(3).
4. Antioxidant and antiangiogenic activities
In the study to investigate the anti-angiogenic activity and antioxidant properties of Myristica fragrans (M. fragrans) (nutmeg) and Morinda citrifolia (M. citrifolia)(mengkudu) oils, indicated that nutmeg oil has higher antioxidant activity than mengkudu oil. The nutmeg oil effectively inhibited the oxidation of linoleic acid with (88.68±0.1)% while the inhibition percentage of oxidation of linoleic acid of the mengkudu oil is (69.44±0.4)%. The nutmeg oil and mengkudu oil showed reducing power with an EC(50) value of 181.4 μg/mL and 3 043.0 μg/mL, respectively. The antiangiogenic activity of nutmeg oil showed significant antiangiogenic activity with IC(50) of 77.64 μg/mL comparing to mengkudu oil which exhibits IC(50) of 109.30 μg/mL(4).
5. Etc.

Side Effects
1. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
2. Do not use the herb in case of diarrhea due to damp-heat infection or food poisoning
3. Do not use the herb in case of hemorrhoids or gum infections
4. Etc.

Pregnancy Miracle
Reverse Infertility And Get Pregnant Naturally
Using Holistic Ancient Chinese Medicine

Chinese Food Therapy

The Best Way to prevent, treat your disease, including Obesity

and restore your health naturally with Chinese diet

Ovarian Cysts And PCOS Elimination

Holistic System In Existence That Will Show You How To

Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer

Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/22149219
(2) http://www.ncbi.nlm.nih.gov/pubmed/16033651
(3) http://www.ncbi.nlm.nih.gov/pubmed/22619922
(3) http://www.ncbi.nlm.nih.gov/pubmed/22449521

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Rou Cong Rong (Herba Cistanches Deserticolae)

Rou Cong Rong (Herba Cistanches Deserticolae)

Rou Cong Rong is also known as Cistanches. The sweet, salty and warm herb has been used in TCM to treat, impotence, constipation, infertility, excessive uterine bleeding, yeast infection, high blood pressure, inflammation of the kidney, etc., as it tonifies the Kidneys, benefits the Yang, moistens the Intestines, Promotes bowel movement, etc. by enhancing the functions of large intestine and kidney channels.

Ingredients
1. Iridoids
2. Cistamin
3. Cistachlorine
4. Cistanosides A, B,C,D,E,F,G,
5. D-mannose,
6. β-Sitostero
7. Succinic acid
8. β-Sitosterol-glucoside
9. Cistanosides H, I,
10. Decaffeoylacteoside
11. Etc.

Health Benefits
1. Prevent bone loss
In the study to assess the ability of traditional Chinese medicine Cistanches Herba extract (CHE) to prevent bone loss in the ovariectomized (OVX) rat, Dr.Liang H, and the research team at Dalian Municipal Central Hospital, showed that The rats in the sham-operated group were anesthetized, laparotomized, and sutured without removing their ovaries. After 1 week of recovery from surgery, the OVX rats were randomly divided into three groups and orally treated with H(2)O (OVX group) or CHE (100 or 200 mg kg(-1) daily) for 3 months. The sham-operated group (n = 8) was orally treated with H(2)O. After 3 months, the total body bone mineral density (BMD), bone mineral content (BMC), Bone biomechanical index, blood mineral levels and blood antioxidant enzymes activities were examined in sham-operated, ovariectomized and Cistanches Herba extract treated rats. Results showed that Cistanches Herba extract treatment significantly dose-dependently enhanced bone mineral density (BMD), bone mineral content (BMC), maximum load, displacement at maximum load, stress at maximum load, load at auto break, displacement at auto break, and stress at auto break, and blood antioxidant enzymes activities, decreased blood Ca, Zn and Cu levels compared to the OVX group(1).

2. Kidney-deficiency syndrome
In the study to investigate the metabolic responses to Herba Cistanches intervention in a rat model of the hydrocortisone-induced ‘kidney-deficiency syndrome’, showed that the intervention of Herba Cistanches caused a systemic recovery from the hydrocortisone-induced metabolic perturbation in rats. This study also demonstrates that metabolic profiling is useful in studying therapeutic mechanisms of herbal medicines(2).

3. Kidney nourishing and yang strengthening functions
Oral administration of water extraction of three kinds of herba cistanches can increase the weight of young mice, prolong the duration of swimming and promote anoxia tolerance in mice. These water decoctions can also increase the body weight, the activities of SOD in serum and the lifespan of “Yang insufficient” model mice induced by administration of hydrocortisone acetate(3).

4. Etc.

Side Effects
1. Do not use the herb in case of spleen deficiency
2. Do not use the herb in case of heat
3. Etc.

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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21954345
(2) http://www.ncbi.nlm.nih.gov/pubmed/18328110
(3) http://www.ncbi.nlm.nih.gov/pubmed/7945844