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Rou Cong Rong (Herba Cistanches Deserticolae)
Ru Xiang is also known as Frankincense Carterii. The acrid, bitter and warm herb has been used in TCM to treat pain due to blood clots, spastic muscle, carbuncles, gum bleeding, gingivitis, rheumatoid arthritis, cirrhosis of liver, amenorrhea, etc., as it moves Blood, calms pain, solves oedema, romotes tissue regeneration, etc. by enhancing the functions of heart, liver and spleen channels.
Ingredients
1. Resin
2. Pinene, Dipentene
3. α Phellandrene
4. β Phellandrene
5. α-amyrone,
6. α-amyrinone
7. α-amyrin
8. β-amyrin
8. Viridiflorol
9. Insensole
10. Insensole oxide
11. Etc.
Health Benefits
1. Arthritis
In the random, blinded study, the anti-arthritic effects of a BC extract were observed and compared to vehicle control in a Lewis rat adjuvant arthritis model (n=8/group), showed that At 0.90 g/kg per day, BC significantly decreased arthritic scores between days 20 and 25 (p<0.05) and reduced paw edema on days 18, 20 and 22 compared to control (p<0.05). It also significantly suppressed local tissue TNF-alpha and IL-1beta (p<0.05). No major adverse effects were observed in animals during the repeated-dose treatment profile although mild fur discoloration was noted(1).
2. Persistent inflammation
In this randomized, blinded study, the antihyperalgesic and antiedema effects of 3 dosages of BC were compared to a vehicle control. Inflammation was induced in rats by injecting complete Freund’s adjuvant (CFA) into one hind paw, showed that BC produces significant antihyperalgesia and anti-inflammation effects and that the antihyperalgesia may be mediated by suppressed inflammation-induced Fos expression in the spinal dorsal horn neurons(2).
3. Antiproliferative and apoptotic activities
In the study to investigate the digallic acid (DGA) purified from Pistacia lentiscus. L fruits for its antiproliferative and apoptotic activities on human lymphoblastoid TK6 cells, showed that the inhibition of lymphoblastoid cell proliferation was noted from 8.5 mug/ml of DGA. The induction of apoptosis was confirmed by DNA fragmentation and PARP cleavage. We have demonstrated that DGA induces apoptosis by activating the caspase-8 extrinsic pathway. Caspase-3 was also activated in a dose dependent manner(3).
4. Anti-inflammatory activity
In the study of the topical anti-inflammatory activity of essential oil of Pistacia lentiscus L., using carrageenan induced rat paw edema and cotton pellet induced granuloma. indicated that on topical application, the oil exhibited a significant decrease in paw edema. The oil also inhibited cotton pellet-induced granuloma, and reduced serum TNF-alpha and IL-6. It can be concluded that the essential oil of Pistacia lentiscus reduces leukocyte migration to the damaged tissue and exhibits anti-inflammatory activity.
5. Etc.
Side Effects
1. Do not use the herb in case of spleen deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.
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(1) http://www.ncbi.nlm.nih.gov/pubmed/15970410
(2) http://www.ncbi.nlm.nih.gov/pubmed/15865500
(3) http://www.ncbi.nlm.nih.gov/pubmed/22686580
(4) http://www.ncbi.nlm.nih.gov/pubmed/22164803
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