Including a portion of fennel in your daily diet may improve the body anti-allergic activities, some scientists suggested.
The results of the differentiation were carried out by numbers of universities and published on online medical literature.
Allergic effect associated with nonharmful allergens caused by an overreaction of the immune system may induce symptoms of skin rash, sneezing,....
In some cases, an allergic reaction can be life-threatening (anaphylaxis), depending on the severity of immune responses.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
Nutrients
1. Carbohydrates
2. Fiber
3. Protein
4. Thiamine (Vitamin B1)
5. Riboflavin (Vitamin B2)
6. Niacin (Vitamin B3)
7. Pantothenic acid (B5)
8. Vitamin B6
9. Folate (Vitamin B9)
10. Vitamin C
11. Calcium
12. Copper
13. Iron
14. Magnesium
15. Molybdenum
16. Phosphorus
17. Potassium
18. Zinc
19. Etc.
In the study to confirm the potential efficacy of fennel for antiallergic use, inhibitory actions of the fruiton 5-lipoxgenase (5-LOX) and β-hexosaminidase release, researchers found that application of fennel extract at ethanol 70% with IC50 of 3.2 μg/ml, exerts a potential effect in inhibited 5-LOX-catalyzed leukotriene production in mediation of allergy, and other immune responses.
β-hexosaminidase released from activated mast cells are responsible for the allergic inflammatory reactions associated with immune response.
5-Lipoxygenase (5-LOX), an enzyme plays important roles in infection and allergic responses.
Although many ingredients isolated from fennel fruit demonstrated an inhibitory effect in the reduced immune overreaction of the unharmful allergens, phenylpropanoid, trans-anethole, showed the considerable inhibitory action of 5-LOX in compared to others, particularly at IC50 of 51.6 μM of trans-anethole
However, the fennel bioactive compound trans-anethole displayed insignificant effect on the degranulation reaction of β-hexosaminidase release from antigen-treated RBL-2H3 cells in compared to other ingredients.
RBL-2H3 cell line is a commonly used histamine-releasing cell line in immunological research of. inflammatory and allergic activities.
These results suggested, depending on the stimulation of allergens, fennel demonstrated anti-allergic activity through expression of different constituents in both the plant (FR) and trans-anethole alone.
Dr. the lead author after taking into account of other co-founders, said, "FR and several major constituents are 5-LOX inhibitors and they may have the potential for treating 5-LOX-related disorders".
Additionally, according to the study of Yonsei University, oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract in tested animal model exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions, a delayed type hypersensitivity usually takes a few days to develop.
Further analysis suggested that application of fennel also reduced inflammatory factors activated by
the immune response in the induction of systemic inflammation against allergens in causing damage to the body through its antioxidants and stimulated productions of antioxidant enzymes from the host, such as superoxide dismutase (SOD) and catalase and the high-density lipoprotein-cholesterol level.in the prevention of lipid peroxidation in initiated by ROS.
Moreover, the application also reduced levels of malondialdehyde (MDA), which is an indication and maker of oxidative stress.
Interestingly, F. vulgare fruit methanolic extract expressed a strong effect in inhibition of nitric oxide (NO) produced by the innate immune system through activated macrophages in inhibited pathogens replication.
The above differentiation was supported by the literature of "Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology"
posted in the BioMed Research International.
According to the study, oral injection of the methanolic extract of F. vulgare fruit at200 mg/kg once a day for 7 days showed a significant inhibitory effect on DNFB- (2,4-dinitrofluorobenzene-) induced delayed type hypersensitivity through fennel immunosuppressive properties.
2,4-dinitrofluorobenzene (DNFB) may induce allergic contact dermatitis.
The information collected indicated that fennel, its bioactive compounds, and extracts may be considered as a functional food for reduced risk immune over the response to unharmful allergens.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) 5-Lipoxygenase Inhibition of the Fructus of Foeniculum vulgare and Its Constituents by Lee JH1, Lee DU, Kim YS, Kim HP. (PubMed)
(2) Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare by Choi EM1, Hwang JK. (PubMed)
(3) Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology by Shamkant B. Badgujar,* Vainav V. Patel, and Atmaram H. Bandivdekar(PubMed)
Saturday, October 6, 2018
Friday, October 5, 2018
Herbal Anise May Process A Cure of Nonalcoholic Fatty Liver Disease (NAFLD), MEDLINE Studies Show
Intake of herbal Anise together with the change of diet pattern may have a potential and substantial effect in the cure of nonalcoholic fatty liver disease (NAFLD).
The nonalcoholic fatty liver disease is a medical condition characterized by fat accumulated in the liver tissue other than excessive consumption of alcohol.
According to the American liver foundation, Nonalcoholic Fatty Liver Disease is one of the most common causes of liver disease and approximately 30% (100 million) individuals in the United States are estimated to have the nonalcoholic fatty liver disease.
The causes of Nonalcoholic Fatty Liver Disease are unknown. Also, as of today researchers do not understand why some people are susceptible to liver fat accumulation while others are not.
However, some researchers suggested that combined health problems such as overweight and obesity, insulin resistance, hyperglycemia, and hyperlipidemia may all contribute to the onset of the diseases.
Prolonged and untreated Nonalcoholic Fatty Liver Disease may induce complication of cirrhosis, a disease characterized by late-stage of fibrosis in the liver and untreated cirrhosis can lead to life-threatening diseases, such as a coma, liver failure, or death.
The Shahid Beheshti University of Medical Science in the examine the results of selected studies including in 33 full texts and 7 articles suggested that
*Intakes of red meat, fats, and sweets are associated with the elevated risk of NAFLD and consumption of whole grains, fruits and vegetables are associated with reduced risk of NAFLD.
* There is a highly positive association between the Western dietary pattern and the risk of NAFLD.
The university experiment also found that adherence to the Mediterranean diet was significantly associated with the attenuated severity of hepatic steatosis through improving insulin sensitivity in an insulin-resistant population with NAFLD,
Anise is a flowering plant of the species of Pimpinella anisum, genus Pimpinella, belongings to the family Apiaceae native to Egypt and the Mediterranean region, used in traditional herbal medicine as a fragrance in soaps, oils, and mouth fresheners and stomachic, antiseptic, anti-spasmodic,...
Chemical constituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.
In the comparison the effect of anise fruit essential oil and extract and risk of nonalcoholic fatty liver disease, the Islamic Azad University conducted an experiment of 60 rats randomly divided into ten groups, six in each group with NAFLD induced by using choline-deficient diet for 90 days and followed by 30 days of treatment with 25, 50, 100, and 200 mg/kg/day of hydroethanolic extract (AE) as well as 0.125, 0.25, and 0.5 mg/kg/day of essential oil (AO)
During the course and the end of the experiment, researchers showed that both applications exert significantly reverse activities in
* Increased plasma levels of total cholesterol, low-density lipoprotein, and triacylglycerol and
* Decreased high-density lipoprotein level caused by choline-deficient diet in a dose-dependent manner.
Additional differentiation also found that AE and AO reduced the elevated levels of enzymes aspartate transaminase (AST) and alanine transaminase (ALT) which are considered as indications of either liver injury or damage caused by the acute inflammation in the experiential subject model.
However, patients with the nonalcoholic fatty liver disease may have normal transaminase levels.
Levels of aspartate aminotransferase (AST) is usually used as a maker to detect liver damage.
Serum levels of alanine aminotransferase (ALT) are the best predictor of NAFLD after considering to other clinical and biochemical features.
Observation of injection of anise AE and AO also exerted a powerful antioxidant activity in significantly lower overexpression of ROS in the exhibited free radical chain reaction in the induction of oxidative stress to precipitate liver toxicity.
According to the St. Louis University Health Sciences Center, overexpression of free radicals in the liver can damage cellular macromolecules in the induction of hepatocellular injury.
Also, in histological findings, both AE and AO displayed a substantial effect in reduced macrovesicular steatohepatitis which is the leading cause of liver cancer.
Further analysis of the experiment, researchers found that both anise AE and AO demonstrated a strong effect in ameliorated lipid peroxidation induced by oxidative stress indicated by elevation of plasma level of 8-isoprostane which is correlated to the prevalence of non-alcoholic fatty liver disease (NAFLD).
Elevated 8-Isoprostane values activated by lipid peroxidation induced by injection of choline-deficient diet were also considered biomarker in patients with nonalcoholic liver disease and correlated to with body mass index and total cholesterol in NAFLD but did not significantly relate to sex, age, biochemical data or iron metabolism markers in all liver diseases.
Therefore, people with high body mass index and high levels of total cholesterol levels are susceptible to increased risk of the diseases.
Taken together, intake of herbal Anise with abundant of bioactive chemical constituents and change of diet pattern with rich of whole grains, fruits, and vegetables may have a higher potential in the cure of nonalcoholic liver disease,
However, further data collection on larger sample and multi-center clinical studies performed with human consumption during the course of the disease will be necessary to complete the picture of its anti nonalcoholic fatty liver disease (NAFLD) possibilities.
Intake of Anise extract should only be prescribed by related field specialist in the prevention of acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease by Asadollahpoor A1, Abdollahi M2, Rahimi R3,(PubMed)
(2) Relationship between Diet and Non-alcoholic Fatty Liver Disease: A Review Article by Mirmiran P1, Amirhamidi Z1, Ejtahed HS1, Bahadoran Z1, Azizi F2(PubMed)
Thursday, October 4, 2018
How to Treat Edema Naturally
Herbal Arnica may have a therapeutic and substantial effect in reducing progression and treatment of edema, some scientists suggested.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries in the treatment of strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of skin, tissues, organs, etc.
Edema is a condition, characterized by excessive accumulation of fluids in some tissues within the body.
Certain diseases including heart, liver, and kidneys may also increase the prevalence of edema as a result of salt retention in the induction of excess fluid accumulation.
Some researchers suggested that the alternation of starling forces which control the transfer of fluid from the vascular compartment to surrounding tissue spaces may be a culprit in facilitated edematous disorders.
However, in compared to diminished organs function in causes of edema, edematous states may share many of the same afferences and efferent mechanisms for sodium and water retention.
Long-term untreated edema may increase complications of painful swelling, difficulty walking. with skin becoming itchy and uncomfortable. In a serious case, it can cause infection in the swollen area and scarring between layers of tissue.
Some patients may also experience decreased blood circulation, the elasticity of arteries, veins, joints, and muscles in the surrounding infectious areas.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the study to compare the efficacy of herbal Arnica and corticosteroids in reduced postoperative edema and bruising associated with rhinoplasty of 48 primary rhinoplasty patients randomly assigned to three groups as follow
* Group P received 10 mg of dexamethasone (intravenously) intraoperatively followed by a 6-day oral tapering dose of methylprednisone.
* Group A received Arnica three times a day for 4 days, and
* Group C received neither agent and served as the control.
3 blinded panelists were assigned to rate the extent of ecchymosis, including the intensity of the ecchymosis, and the severity of the edema
After observation of the study over the entire period, scientists found that
* There were no significant differences in all groups on the day 2 of postoperative
* In compared to increased swelling of the control group, both group A and P demonstrated a significant improvement in edema rating.
Interestingly, conventional medicine administration group exerted higher intensity of ecchymosis compared to groups A and C on the day of postoperative and all groups displayed no difference of magnitude of edema.
However, between the period of day 2 and 8, groups A and C exhibited significantly more resolution of ecchymosis in compared to group P.
The results suggested that although Arnica may have a therapeutic property in reducing edema during the early postoperative period. And the herbal medicine did not provide similar benefits in regard to the extent and intensity of ecchymosis in compared to corticosteroids.
In order to further confirmation of the effect of herbal Arnica in reduced postoperative ecchymosis and edema, researchers at the joint study lead University of Miami Miller School of Medicine, conducted an investigation in a select population of healthy volunteers after oculofacial surgery by examining the postoperative course and medical records of a total of 27 patients (16 females, 11 males) with age range from18 to 70 years using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
According to the result of the experiment, application of Arnica 50 M (10) 50% and Ledum 50 M (10) pads bilaterally after surgery through postoperative day 6, showed a significantly accelerated healing from day 7 to day 12 in dose depending manner, without inflicting any adverse effects.
The findings suggested that application of composited Arnica and Ledum displays a potential efficacy in reducing postoperative ecchymosis and edema after oculofacial surgery.
The above differentiation of herbal Arnica in improved edema after surgery was supported by the joint study led by the Research Center of University of adult male Wistar rats inoculated with 1% carrageenan into the footpad to induce edema then treated with Arnica montana 6cH, dexamethasone (4.0 mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation.
According to the investigation, application of Arnica group exhibited anti-edema through increased lymphatic edema absorption, particularly, in late edema and less intense edema treatment group after adjusting to the individually qualitative of inflammatory vascular events.
Moreover, the edema inhibition of Arnica was attributed to significantly reduced mast cell degranulation and increased lymphatic vessels diameter and decreased the production of prostaglandins associated to the development of edema, caused by subcutaneous carrageenan injection in the induction of local inflammation.
Taken together, herbal Arnica may be considered as a functional food in reduced risk, progression and for treatment of edema and ecchymosis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A randomized, controlled comparison between arnica and steroids in the management of postrhinoplasty ecchymosis and edema by Totonchi A1, Guyuron B.(PubMed)
(2) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW. (PubMed)
(3) Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation Ana Paula Kawakami,1 Cesar Sato,1 Thayna Neves Cardoso,1 and Leoni Villano Bonamin(Hindawi)
(4) Pathogenesis of sodium and water retention in edematous disorders by Paller MS, Schrier RW(PubMed)
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, native to Europe and Asia, used in herbal medicine for centuries in the treatment of strains, sprains, and bruises.
Wound healing is a process of repairing after the damage of skin, tissues, organs, etc.
Edema is a condition, characterized by excessive accumulation of fluids in some tissues within the body.
Certain diseases including heart, liver, and kidneys may also increase the prevalence of edema as a result of salt retention in the induction of excess fluid accumulation.
Some researchers suggested that the alternation of starling forces which control the transfer of fluid from the vascular compartment to surrounding tissue spaces may be a culprit in facilitated edematous disorders.
However, in compared to diminished organs function in causes of edema, edematous states may share many of the same afferences and efferent mechanisms for sodium and water retention.
Long-term untreated edema may increase complications of painful swelling, difficulty walking. with skin becoming itchy and uncomfortable. In a serious case, it can cause infection in the swollen area and scarring between layers of tissue.
Some patients may also experience decreased blood circulation, the elasticity of arteries, veins, joints, and muscles in the surrounding infectious areas.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivatives.
In the study to compare the efficacy of herbal Arnica and corticosteroids in reduced postoperative edema and bruising associated with rhinoplasty of 48 primary rhinoplasty patients randomly assigned to three groups as follow
* Group P received 10 mg of dexamethasone (intravenously) intraoperatively followed by a 6-day oral tapering dose of methylprednisone.
* Group A received Arnica three times a day for 4 days, and
* Group C received neither agent and served as the control.
3 blinded panelists were assigned to rate the extent of ecchymosis, including the intensity of the ecchymosis, and the severity of the edema
After observation of the study over the entire period, scientists found that
* There were no significant differences in all groups on the day 2 of postoperative
* In compared to increased swelling of the control group, both group A and P demonstrated a significant improvement in edema rating.
Interestingly, conventional medicine administration group exerted higher intensity of ecchymosis compared to groups A and C on the day of postoperative and all groups displayed no difference of magnitude of edema.
However, between the period of day 2 and 8, groups A and C exhibited significantly more resolution of ecchymosis in compared to group P.
The results suggested that although Arnica may have a therapeutic property in reducing edema during the early postoperative period. And the herbal medicine did not provide similar benefits in regard to the extent and intensity of ecchymosis in compared to corticosteroids.
In order to further confirmation of the effect of herbal Arnica in reduced postoperative ecchymosis and edema, researchers at the joint study lead University of Miami Miller School of Medicine, conducted an investigation in a select population of healthy volunteers after oculofacial surgery by examining the postoperative course and medical records of a total of 27 patients (16 females, 11 males) with age range from18 to 70 years using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
According to the result of the experiment, application of Arnica 50 M (10) 50% and Ledum 50 M (10) pads bilaterally after surgery through postoperative day 6, showed a significantly accelerated healing from day 7 to day 12 in dose depending manner, without inflicting any adverse effects.
The findings suggested that application of composited Arnica and Ledum displays a potential efficacy in reducing postoperative ecchymosis and edema after oculofacial surgery.
The above differentiation of herbal Arnica in improved edema after surgery was supported by the joint study led by the Research Center of University of adult male Wistar rats inoculated with 1% carrageenan into the footpad to induce edema then treated with Arnica montana 6cH, dexamethasone (4.0 mg/kg; positive control) or 5% hydroalcoholic solution (negative control), per os, each 15 minutes, between 30 and 180 minutes after the irritant inoculation.
According to the investigation, application of Arnica group exhibited anti-edema through increased lymphatic edema absorption, particularly, in late edema and less intense edema treatment group after adjusting to the individually qualitative of inflammatory vascular events.
Moreover, the edema inhibition of Arnica was attributed to significantly reduced mast cell degranulation and increased lymphatic vessels diameter and decreased the production of prostaglandins associated to the development of edema, caused by subcutaneous carrageenan injection in the induction of local inflammation.
Taken together, herbal Arnica may be considered as a functional food in reduced risk, progression and for treatment of edema and ecchymosis.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A randomized, controlled comparison between arnica and steroids in the management of postrhinoplasty ecchymosis and edema by Totonchi A1, Guyuron B.(PubMed)
(2) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW. (PubMed)
(3) Inflammatory Process Modulation by Homeopathic Arnica montana 6CH: The Role of Individual Variation Ana Paula Kawakami,1 Cesar Sato,1 Thayna Neves Cardoso,1 and Leoni Villano Bonamin(Hindawi)
(4) Pathogenesis of sodium and water retention in edematous disorders by Paller MS, Schrier RW(PubMed)
Wednesday, October 3, 2018
How To Protect Your Eyes Against Retinal Degeneration
Green tea phenolic content may have a sustainable and therapeutic effect in reduced risk and progression of retinal degeneration, some scientists suggested.
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in natural herbal medicine or food, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weakening immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Retinal degeneration is a macular disease characterized by impaired vision, night blindness, retinal detachment, light sensitivity, tunnel vision, and loss of peripheral vision to total loss of vision.
The evaluation of green tea effect in risk of retinal degeneration was found to be implicated by several mechanisms through numbers of aspects.
In ROS implication of oxidative stress-induced degeneration of the retina occurred in age-related macular degeneration (AMD) and glaucoma, application of green tea polyphenols epigallocatechin gallate (EGCG) exhibited antioxidant effect as free radical scavenger in ameliorated chain reaction of ROS in causing loss of neuron with direct effects of retinal function and reduced cytotoxicity of free radicals in induction of retinal cellular apoptosis.
Administration of green tea phenolic compound exerted 10 times more effective in the treatment of retinal degeneration, in compared to potent medicine Trolox (vitamin E analog) in attenuating lipid peroxidation caused by the nitric oxide donor, sodium nitroprusside (SNP), according to the study.
Particularly, green tea epigallocatechin gallate (EGCG) inhibited a significant decrease of photoreceptor-specific markers (RET-P1, rhodopsin kinase), an indication of photoreceptor cells in the transition to degenerate prematurely, eventually resulting in blindness.
Also, the application reduced an increase in the cell death marker caspase-3 caused by oxidative stress induced by injection of sodium nitroprusside (SNP)
Caspase 3 is an important marker of apoptosis and one of side effect of sodium nitroprusside (SNP) is cyanide toxicity, that can induce overexpression ROS in facilitated free radical chain reaction.
According to the observation by Western blotting techniques, SNP was completely inhibited by EGCG injection in ameliorated the detrimental effects to the retina.
Dr. Zhang B, the co-author said, "Since oxidative stress has been implicated in retinal diseases like AMD and glaucoma this study provides "proof of principle" for the idea that daily intake of EGCG may help individuals suffering from retinal diseases where oxidative stress is implicated".
More interestingly, BALB/cJ mice treated with either EGCG or saline via intraperitoneal (IP) injection, and then placed under constant cool white light-emitting diode (LED) light (10,000 lux) for 5 h, showed a strong protective effect on the retina against light damage (LD) in compared to the control group.
In the examine the retinal structure and function after LD, according to the optical coherence tomography (OCT) and electroretinography (ERG), application of green tea EGCG improved significantly higher ERG amplitudes for all three wave types through inducing morphologic protection of photoreceptors in compared to control.
Moreover, the green tea extract bio-compound also decreased oxidative stress through increase the mRNA level of the antioxidant expression of Sod2, a manganese-dependent superoxide dismutase (MnSOD) before LD and 24 h after LD.
Dr. Qi S1,, the lead author said, "The IP injection of EGCG attenuated the detrimental effects of bright light on the retinas of BALB/cJ mice by protecting the structure and function of the retina".
Importantly, in the study to evaluate green tea EGCG effect in reduced glutamate and induced excitotoxicity in the retina, researchers conducted a study of female Wistar rats (n = 171) randomly assigned into
*. A normal control group (n = 9);
*. A saline control group with intravitreal saline injections (n = 54);
*. NMDA control group with an intravitreal NMDA injection;
*. Intraperitoneal saline injections (n = 54); and
*. NMDA study group (n = 54) receiving an intravitreal NMDA injection plus intraperitoneal EGCG (25 mg/kg) injections.
Observation of the groups at 2 weeks after additional injection of NMDA, showed that group treated with intraperitoneal application of EGCG reduced a significantly less marked NMDA-associated loss of retinal ganglion cell, through
* Inhibition of decreasing retinal ganglion cell layer (GCL), neurons located near the inner surface (the ganglion cell layer) of the retina of the eye in received visual information from photoreceptors.
These results were observed by differentiation of Thy-1 immunoreactivity in several areas of the immature and adult human brain in the expression of retinal ganglion cell damage.
Thy-1 is mostly is expressed by the ganglion cells within the retina and used to index ganglion cell death after ischemia and excitotoxicity. and NMDA excitotoxicity is associated with the death of retinal ganglion cells (RGCs).
Taken together, there is no doubt that Epigallocatechin-3-gallate (EGCG), a major polyphenol of green tea, may be used a combination with standard therapy for protection and treatment of retinal degenerative disease
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in natural herbal medicine or food, long-term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weakening immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.
Retinal degeneration is a macular disease characterized by impaired vision, night blindness, retinal detachment, light sensitivity, tunnel vision, and loss of peripheral vision to total loss of vision.
The evaluation of green tea effect in risk of retinal degeneration was found to be implicated by several mechanisms through numbers of aspects.
In ROS implication of oxidative stress-induced degeneration of the retina occurred in age-related macular degeneration (AMD) and glaucoma, application of green tea polyphenols epigallocatechin gallate (EGCG) exhibited antioxidant effect as free radical scavenger in ameliorated chain reaction of ROS in causing loss of neuron with direct effects of retinal function and reduced cytotoxicity of free radicals in induction of retinal cellular apoptosis.
Administration of green tea phenolic compound exerted 10 times more effective in the treatment of retinal degeneration, in compared to potent medicine Trolox (vitamin E analog) in attenuating lipid peroxidation caused by the nitric oxide donor, sodium nitroprusside (SNP), according to the study.
Particularly, green tea epigallocatechin gallate (EGCG) inhibited a significant decrease of photoreceptor-specific markers (RET-P1, rhodopsin kinase), an indication of photoreceptor cells in the transition to degenerate prematurely, eventually resulting in blindness.
Also, the application reduced an increase in the cell death marker caspase-3 caused by oxidative stress induced by injection of sodium nitroprusside (SNP)
Caspase 3 is an important marker of apoptosis and one of side effect of sodium nitroprusside (SNP) is cyanide toxicity, that can induce overexpression ROS in facilitated free radical chain reaction.
According to the observation by Western blotting techniques, SNP was completely inhibited by EGCG injection in ameliorated the detrimental effects to the retina.
Dr. Zhang B, the co-author said, "Since oxidative stress has been implicated in retinal diseases like AMD and glaucoma this study provides "proof of principle" for the idea that daily intake of EGCG may help individuals suffering from retinal diseases where oxidative stress is implicated".
More interestingly, BALB/cJ mice treated with either EGCG or saline via intraperitoneal (IP) injection, and then placed under constant cool white light-emitting diode (LED) light (10,000 lux) for 5 h, showed a strong protective effect on the retina against light damage (LD) in compared to the control group.
In the examine the retinal structure and function after LD, according to the optical coherence tomography (OCT) and electroretinography (ERG), application of green tea EGCG improved significantly higher ERG amplitudes for all three wave types through inducing morphologic protection of photoreceptors in compared to control.
Moreover, the green tea extract bio-compound also decreased oxidative stress through increase the mRNA level of the antioxidant expression of Sod2, a manganese-dependent superoxide dismutase (MnSOD) before LD and 24 h after LD.
Dr. Qi S1,, the lead author said, "The IP injection of EGCG attenuated the detrimental effects of bright light on the retinas of BALB/cJ mice by protecting the structure and function of the retina".
Importantly, in the study to evaluate green tea EGCG effect in reduced glutamate and induced excitotoxicity in the retina, researchers conducted a study of female Wistar rats (n = 171) randomly assigned into
*. A normal control group (n = 9);
*. A saline control group with intravitreal saline injections (n = 54);
*. NMDA control group with an intravitreal NMDA injection;
*. Intraperitoneal saline injections (n = 54); and
*. NMDA study group (n = 54) receiving an intravitreal NMDA injection plus intraperitoneal EGCG (25 mg/kg) injections.
Observation of the groups at 2 weeks after additional injection of NMDA, showed that group treated with intraperitoneal application of EGCG reduced a significantly less marked NMDA-associated loss of retinal ganglion cell, through
* Inhibition of decreasing retinal ganglion cell layer (GCL), neurons located near the inner surface (the ganglion cell layer) of the retina of the eye in received visual information from photoreceptors.
These results were observed by differentiation of Thy-1 immunoreactivity in several areas of the immature and adult human brain in the expression of retinal ganglion cell damage.
Thy-1 is mostly is expressed by the ganglion cells within the retina and used to index ganglion cell death after ischemia and excitotoxicity. and NMDA excitotoxicity is associated with the death of retinal ganglion cells (RGCs).
Taken together, there is no doubt that Epigallocatechin-3-gallate (EGCG), a major polyphenol of green tea, may be used a combination with standard therapy for protection and treatment of retinal degenerative disease
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate by Zhang B1, Osborne NN(PubMed)
(2) Neuroprotective effect of epigallocatechin-3-gallate against N-methyl-D-aspartate-induced excitotoxicity in the adult rat retina by Chen F1, Jiang L, Shen C, Wan H, Xu L, Wang N, Jonas JB(PubMed)
(3) Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina by Qi S1,2, Wang C1,2, Song D2, Song Y2, Dunaief JL2. (PubMed)--
(1) Oxidative-induced retinal degeneration is attenuated by epigallocatechin gallate by Zhang B1, Osborne NN(PubMed)
(2) Neuroprotective effect of epigallocatechin-3-gallate against N-methyl-D-aspartate-induced excitotoxicity in the adult rat retina by Chen F1, Jiang L, Shen C, Wan H, Xu L, Wang N, Jonas JB(PubMed)
(3) Intraperitoneal injection of (-)-Epigallocatechin-3-gallate protects against light-induced photoreceptor degeneration in the mouse retina by Qi S1,2, Wang C1,2, Song D2, Song Y2, Dunaief JL2. (PubMed)--
Monday, October 1, 2018
How to Mediate Your Sex Hormone to the Body Needed Naturally
Coffee, a popular and social beverage, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
A recent study suggested that coffee may have a direct effect on the influence of sex hormone steroid-binding globulin(SSBG) in the stimulated production of estrogen and testosterone depending to levels in the host.
Sex hormones are a class of hormones, affecting sexual development or reproduction. Steroid-binding globulin(SSBG), is a sex hormone, having a direct effect on androgen and estrogen.
In sex hormones and sexual differentiation, the most influential hormone in human sexual desire is testosterone.
Low levels of estrogen in women can also reduce sex drive caused by vaginal dryness that can lead to painful intercourse
Mentally, women with low levels of estrogen also experience unstable mood and sleep patterns that can have a strong impact on sexual desire.
However, sexual motivation is influenced by a set of hormones, including testosterone, estrogen, progesterone, oxytocin, and vasopressin...... Altogether, they control the ability to engage in sexual behaviors.
In an 8-week parallel-arm randomized controlled trial with Healthy adults (n = 42) recruited from the Boston community, including regular coffee consumers, nonsmokers, and overweight, randomized to five 6-ounce cups of caffeinated or decaffeinated instant coffee or water per day, at 4 weeks, researchers surprisingly found that
* Decaffeinated coffee drinking was associated with a borderline significantly increased levels of SHBG in women, but not in men.
*. At week 4, decaffeinated coffee decreased total and free testosterone and caffeinated coffee decreased only total testosterone in women.
*. Contrast to women participants, men consumption of caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol hormones.
*. The study also indicated that caffeinated coffee consumption does not exert any effect on SHBG in either men or women.
These results suggested that intake of coffee may have a strong impact in maintained normal levels of SHBG, thus reducing the risk of low levels of SHBG induced higher testosterone levels in overweight women, which can lead to androgenization and development of the polycystic ovarian syndrome.
And in men, higher levels of testosterone may also have a significant contribution of healthy libido, building muscle mass, and maintaining energy levels.
Some researchers suggested that increased testosterone level for middle-aged (30 to 50 years old) and older males may also improve the physical energy, strength, stamina, mental aggressiveness which were lost in the aging population.
Contrast to above differentiation, in type 2 diabetic patients, coffee and coffee caffeine showed an elevated effect as a mediator of sex hormone-binding globulin in both androgen and estrogen particularly in women in compared to the healthy young adult.
Dr. Eric L. Ding and colleagues in the study to evaluate "Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men" said, " Among women, higher plasma levels of sex hormone–binding globulin were prospectively associated with a lower risk of type 2 diabetes and " the predicted odds ratio of type 2 diabetes per standard-deviation increase in the plasma level of sex hormone–binding globulin was 0.28 (95% CI, 0.13 to 0.58) among women and 0.29 (95% CI, 0.15 to 0.58) among men".
The analysis strongly suggested that coffee regardless of types have a negative correlation with risk of diabetes through increasing levels of SHBG.
Additionally, according to the cross-sectional study of 2377 nondiabetic pre- and postmenopausal women from the E3N cohort study in a multivariate-adjusted model, intake of more than 3 cups of coffee daily coffee and caffeine ≥265 mg/day were associated with an increased SHBG level distribution (<46.3 nmol/L), in compared to no risk association of decaffeinated coffee subgroup.
In other words, in low levels of SHBG nondiabetic pre- and postmenopausal in compared to healthy women, injection of caffeinated coffee increased levels of sex hormones estrogen and testosterone
The above analysis was supported by the examination of the study during a median follow-up of 10 years of 359 postmenopausal women with newly diagnosed type 2 diabetes matched with 359 control subjects by age, race, duration of follow-up, and time of blood draw, coffee and caffeine were associated with increased levels of free and total testosterone among postmenopausal women.
In Summary, the evidence indicated that coffee and caffeine have an extreme effect in an exhibition of sex hormone estrogen and testosterone through the increased lower level of SHBG in menopause women and prevented the onset of type 2 diabetes without affecting the serum in healthy individuals.
Decaffeinated coffee decreased total and free testosterone through significantly increased levels of SHBG in overweight women who are at risk of diseases associated to over expression of testosterone.
And caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol in men.
Altogether, coffee may be considered as a function food in the mediated production of sexual hormone estrogen and testosterone against diseases and syndromes caused by low levels of SSBG.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
A recent study suggested that coffee may have a direct effect on the influence of sex hormone steroid-binding globulin(SSBG) in the stimulated production of estrogen and testosterone depending to levels in the host.
Sex hormones are a class of hormones, affecting sexual development or reproduction. Steroid-binding globulin(SSBG), is a sex hormone, having a direct effect on androgen and estrogen.
In sex hormones and sexual differentiation, the most influential hormone in human sexual desire is testosterone.
Low levels of estrogen in women can also reduce sex drive caused by vaginal dryness that can lead to painful intercourse
Mentally, women with low levels of estrogen also experience unstable mood and sleep patterns that can have a strong impact on sexual desire.
However, sexual motivation is influenced by a set of hormones, including testosterone, estrogen, progesterone, oxytocin, and vasopressin...... Altogether, they control the ability to engage in sexual behaviors.
In an 8-week parallel-arm randomized controlled trial with Healthy adults (n = 42) recruited from the Boston community, including regular coffee consumers, nonsmokers, and overweight, randomized to five 6-ounce cups of caffeinated or decaffeinated instant coffee or water per day, at 4 weeks, researchers surprisingly found that
* Decaffeinated coffee drinking was associated with a borderline significantly increased levels of SHBG in women, but not in men.
*. At week 4, decaffeinated coffee decreased total and free testosterone and caffeinated coffee decreased only total testosterone in women.
*. Contrast to women participants, men consumption of caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol hormones.
*. The study also indicated that caffeinated coffee consumption does not exert any effect on SHBG in either men or women.
These results suggested that intake of coffee may have a strong impact in maintained normal levels of SHBG, thus reducing the risk of low levels of SHBG induced higher testosterone levels in overweight women, which can lead to androgenization and development of the polycystic ovarian syndrome.
And in men, higher levels of testosterone may also have a significant contribution of healthy libido, building muscle mass, and maintaining energy levels.
Some researchers suggested that increased testosterone level for middle-aged (30 to 50 years old) and older males may also improve the physical energy, strength, stamina, mental aggressiveness which were lost in the aging population.
Contrast to above differentiation, in type 2 diabetic patients, coffee and coffee caffeine showed an elevated effect as a mediator of sex hormone-binding globulin in both androgen and estrogen particularly in women in compared to the healthy young adult.
Dr. Eric L. Ding and colleagues in the study to evaluate "Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men" said, " Among women, higher plasma levels of sex hormone–binding globulin were prospectively associated with a lower risk of type 2 diabetes and " the predicted odds ratio of type 2 diabetes per standard-deviation increase in the plasma level of sex hormone–binding globulin was 0.28 (95% CI, 0.13 to 0.58) among women and 0.29 (95% CI, 0.15 to 0.58) among men".
The analysis strongly suggested that coffee regardless of types have a negative correlation with risk of diabetes through increasing levels of SHBG.
Additionally, according to the cross-sectional study of 2377 nondiabetic pre- and postmenopausal women from the E3N cohort study in a multivariate-adjusted model, intake of more than 3 cups of coffee daily coffee and caffeine ≥265 mg/day were associated with an increased SHBG level distribution (<46.3 nmol/L), in compared to no risk association of decaffeinated coffee subgroup.
In other words, in low levels of SHBG nondiabetic pre- and postmenopausal in compared to healthy women, injection of caffeinated coffee increased levels of sex hormones estrogen and testosterone
The above analysis was supported by the examination of the study during a median follow-up of 10 years of 359 postmenopausal women with newly diagnosed type 2 diabetes matched with 359 control subjects by age, race, duration of follow-up, and time of blood draw, coffee and caffeine were associated with increased levels of free and total testosterone among postmenopausal women.
In Summary, the evidence indicated that coffee and caffeine have an extreme effect in an exhibition of sex hormone estrogen and testosterone through the increased lower level of SHBG in menopause women and prevented the onset of type 2 diabetes without affecting the serum in healthy individuals.
Decaffeinated coffee decreased total and free testosterone through significantly increased levels of SHBG in overweight women who are at risk of diseases associated to over expression of testosterone.
And caffeinated coffee displayed a significantly increased total testosterone and decreased total and free estradiol in men.
Altogether, coffee may be considered as a function food in the mediated production of sexual hormone estrogen and testosterone against diseases and syndromes caused by low levels of SSBG.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial by Wedick NM1, Mantzoros CS, Ding EL, Brennan AM, Rosner B, Rimm EB, Hu FB, van Dam RM.( PubMed)
(2) Cross-sectional association of coffee and caffeine consumption with sex hormone-binding globulin in healthy nondiabetic women by Pihan-Le Bars F1,2, Gusto G3,4,5, Boutron-Ruault MC3,4,5, Fagherazzi G3,4,5, Bonnet F1,2,3.(PubMed)
(3) Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women by Goto A1, Song Y, Chen BH, Manson JE, Buring JE, Liu S.(PubMed)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) The effects of caffeinated and decaffeinated coffee on sex hormone-binding globulin and endogenous sex hormone levels: a randomized controlled trial by Wedick NM1, Mantzoros CS, Ding EL, Brennan AM, Rosner B, Rimm EB, Hu FB, van Dam RM.( PubMed)
(2) Cross-sectional association of coffee and caffeine consumption with sex hormone-binding globulin in healthy nondiabetic women by Pihan-Le Bars F1,2, Gusto G3,4,5, Boutron-Ruault MC3,4,5, Fagherazzi G3,4,5, Bonnet F1,2,3.(PubMed)
(3) Coffee and caffeine consumption in relation to sex hormone-binding globulin and risk of type 2 diabetes in postmenopausal women by Goto A1, Song Y, Chen BH, Manson JE, Buring JE, Liu S.(PubMed)
Sunday, September 30, 2018
How to Improve Your Digestive Functioning Naturally
Fennel may have a therapeutic and profound effect in improving the digestive system in absorbed nutrients and fluids from foods intake, some scientists suggested.
The result of this efficacy was published online by several respectable institutes, including the University of Illinois at Chicago and Afyon Kocatepe University.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the study, researchers set out a criteria and guideline to investigate the effect of fennel in gram-negative bacterium Helicobacter pylori (HP), the microorganisms has been associated with the development of gastritis and peptic ulcer disease to confirm the theory of used in traditional medicine fennel to treat a wide range of ailments, including gastrointestinal (GI) disorders such as dyspepsia, gastritis and peptic ulcer disease (PUD), application of methanol extracts of botanicals with a MIC of 50 microg/mL included Achillea millefolium, Foeniculum vulgare (seed), exerted a significantly inhibitory effect against all susceptibility of 15 HP strains.
These results suggested that injection of fennel displays a potential effect in balanced the ratio of microorganisms in the gastrointestinal tract, thus improving the function in absorbed and distributed nutrients to the body.
These properties reassured the herbal medicine used in practice for the treatment of numbers symptoms of the digestive disorder.
Furthermore, in an animal model with rat induced gastric lesions induced by injection of ethanol, application of aqueous extracts of Foeniculum vulgare (FVE) showed a strong activity in inhibiting the ulcerogenic expression through its antioxidant activities.
In observation of the efficacy of 60 minutes pre-administration of the doses of fennel extracts at 75, 150 and 300 mg/kg, with famotidine, histamine H₂ receptor antagonist with a function to inhibit stomach acid production at the dose of 20 mg/kg, before injection of ethanol, researchers found that
* Pretreatment of all doses exerts significant gastric protective effects in reduced injury and damage caused by injection of ethanol.
* Fennel extract demonstrates a therapeutic activity linearly in compared to other doses and control at a dose of 300 mg/kg
* These activities were associated to reduce the malondialdehyde (MDA) levels, a marker in the expression of severe levels of oxidative stress.
Additional analysis, also suggested that fennel stimulated gastro-protect effect through its antioxidants and facilitated production of antioxidants in the body tissues in inhibited the overexpression of free radicals, thus maintaining the ratio of microorganisms in the digestive tract and its functioning.
After, taking into account of other co and confounders, researchers also suggested that the results in part may also be attributed to antioxidant in ameliorated lipid peroxidation.
The above differentiation was supported by the joint report lead by the Joint Keio University, in the investigation of fennel properties in associated to functional dyspepsia (FD), a functional gastrointestinal disorder characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain.
Truly, delayed gastric emptying and impaired gastric accommodation were found to play important roles in the development of FD.
Anethole (1-methoxy-4-((E)-propenyl)-benzene), a major component of fennel essential oil, in rodents exerted a huge effect in improved clonidine-induced delayed gastric emptying, orally.
Also, application of fennel oil plus Anchu-san (a Japanese herbal medicine containing anethole) demonstrated an important activity in reduced risk of functional dyspepsia (FD) through restoring the delayed gastric emptying.
In other words, anethole processes a gastroprotective efficacy through stimulating gastric accommodation.
Taken together, whole fennel, fennel essential oil, and its bioactive compound anethole may be used as a secondary application in reduced risk and treatment of the digestive disorder.
Adding a portion of fennel in your diet may improve the digestive function in absorption nutrients and fluids from the food intake.
However, intake of supplement should be taken with extreme care as an overdose may cause acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders by Mahady GB1, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR. (PubMed)
(2) Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats by Birdane FM1, Cemek M, Birdane YO, Gülçin I, Büyükokuroğlu ME. (PubMed)
(3) Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents by Asano T1, Aida S2, Suemasu S2, Mizushima T3. (PubMed)
The result of this efficacy was published online by several respectable institutes, including the University of Illinois at Chicago and Afyon Kocatepe University.
Fennel (Foeniculum vulgare) is a plant species of genus, belongings to Apiaceae (Umbelliferae), native to the Mediterranean, used in traditional and herbal medicine as warming, carminative, antispasmodic, antidepressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, to regulate the menstrual cycle and relieve PMS,...
According to the study, researchers set out a criteria and guideline to investigate the effect of fennel in gram-negative bacterium Helicobacter pylori (HP), the microorganisms has been associated with the development of gastritis and peptic ulcer disease to confirm the theory of used in traditional medicine fennel to treat a wide range of ailments, including gastrointestinal (GI) disorders such as dyspepsia, gastritis and peptic ulcer disease (PUD), application of methanol extracts of botanicals with a MIC of 50 microg/mL included Achillea millefolium, Foeniculum vulgare (seed), exerted a significantly inhibitory effect against all susceptibility of 15 HP strains.
These results suggested that injection of fennel displays a potential effect in balanced the ratio of microorganisms in the gastrointestinal tract, thus improving the function in absorbed and distributed nutrients to the body.
These properties reassured the herbal medicine used in practice for the treatment of numbers symptoms of the digestive disorder.
Furthermore, in an animal model with rat induced gastric lesions induced by injection of ethanol, application of aqueous extracts of Foeniculum vulgare (FVE) showed a strong activity in inhibiting the ulcerogenic expression through its antioxidant activities.
In observation of the efficacy of 60 minutes pre-administration of the doses of fennel extracts at 75, 150 and 300 mg/kg, with famotidine, histamine H₂ receptor antagonist with a function to inhibit stomach acid production at the dose of 20 mg/kg, before injection of ethanol, researchers found that
* Pretreatment of all doses exerts significant gastric protective effects in reduced injury and damage caused by injection of ethanol.
* Fennel extract demonstrates a therapeutic activity linearly in compared to other doses and control at a dose of 300 mg/kg
* These activities were associated to reduce the malondialdehyde (MDA) levels, a marker in the expression of severe levels of oxidative stress.
Additional analysis, also suggested that fennel stimulated gastro-protect effect through its antioxidants and facilitated production of antioxidants in the body tissues in inhibited the overexpression of free radicals, thus maintaining the ratio of microorganisms in the digestive tract and its functioning.
After, taking into account of other co and confounders, researchers also suggested that the results in part may also be attributed to antioxidant in ameliorated lipid peroxidation.
The above differentiation was supported by the joint report lead by the Joint Keio University, in the investigation of fennel properties in associated to functional dyspepsia (FD), a functional gastrointestinal disorder characterized by persistent or recurrent postprandial upper abdominal discomfort and epigastric pain.
Truly, delayed gastric emptying and impaired gastric accommodation were found to play important roles in the development of FD.
Anethole (1-methoxy-4-((E)-propenyl)-benzene), a major component of fennel essential oil, in rodents exerted a huge effect in improved clonidine-induced delayed gastric emptying, orally.
Also, application of fennel oil plus Anchu-san (a Japanese herbal medicine containing anethole) demonstrated an important activity in reduced risk of functional dyspepsia (FD) through restoring the delayed gastric emptying.
In other words, anethole processes a gastroprotective efficacy through stimulating gastric accommodation.
Taken together, whole fennel, fennel essential oil, and its bioactive compound anethole may be used as a secondary application in reduced risk and treatment of the digestive disorder.
Adding a portion of fennel in your diet may improve the digestive function in absorption nutrients and fluids from the food intake.
However, intake of supplement should be taken with extreme care as an overdose may cause acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299
Sources
(1) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders by Mahady GB1, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR. (PubMed)
(2) Beneficial effects of Foeniculum vulgare on ethanol-induced acute gastric mucosal injury in rats by Birdane FM1, Cemek M, Birdane YO, Gülçin I, Büyükokuroğlu ME. (PubMed)
(3) Anethole restores delayed gastric emptying and impaired gastric accommodation in rodents by Asano T1, Aida S2, Suemasu S2, Mizushima T3. (PubMed)
Saturday, September 29, 2018
How to Accelerate Ecchymosis Healing
Arnica may have a potential and therapeutic effect in reduced expression of Ecchymosis, some scientists suggested.
The results of these efficacy were confirmed by some studies conducted by numbers of respectable institutes, including University of Miami Miller School of Medicine and University of South Florida.
Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases it is caused by bruising.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing of damage of skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.
In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who under went rhinoplasty, the most common facial plastic surgical procedure, researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).
According to the final searching of 11 trials satisfied the criteria and guideline with a total of 627 patients, application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in compared to the control group.
However, eyelid ecchymosis during the first 24 h postoperatively were statistically decreased in the cold compression group in compared to the control and treatment group.
Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.
Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than those of control.
Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis in compared to non-packing.
Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers launched a review to examine the postoperative course, using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
A total of 27 patients (16 females, 11 males) with age range of 18 to 70 years were included in the study.
Selected medical review showed that patients applied bilaterally topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) after surgery through postoperative day(POD) 6 at each postoperative visit.
These results of everyday progression in patients were evaluated by their respective surgeons.
The physician-patient rating score were used to compare each patient's observed healing in each group.
Photographs in each examination also were recorded.
The median duration of follow-up was 7 days, range from 1 to 14 days.
According to the rating of final examination,
* The proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.
* The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.
* The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly higher than the over all and time point proportion of the other groups at (post operative day) POD 3 to 5 (85.7%), POD 6 to 8 (60.0% ), and overall (51.9%) without inducing any adverse effects.
The findings suggested that combination of Arnica/Ledum were more effective in compared to other treatments.
Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis...., after oculofacial surgery".
Taken together, topical Arnica may be used alone or combined with other herbal medicine to accelerate the healing of ecchymosis
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
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Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)
The results of these efficacy were confirmed by some studies conducted by numbers of respectable institutes, including University of Miami Miller School of Medicine and University of South Florida.
Ecchymosis is a condition of discoloration of the skin as a result of bleeding underneath. In most cases it is caused by bruising.
Arnica is a herbaceous species, genus perennial, belongings to the family Asteraceae, antive to Europe and Asia, used in herbal medicine for centuries to treat strains, sprains, and bruises.
Wound healing is process of repairing of damage of skin, tissues, organs, etc.
The ingredients
Helenalin, chamissonolid, Sesquiterpene lactone, lignans of the furofuran, dibenzylbutyrolactone, dibenzylbutyrolactol types, pinoresinol, epipinoresinol, phillygenin, matairesinol, nortrachelogenin, and nortracheloside, six dibenzylbutyrolactol derivative.
In order to confirm the effect of herbal Arnice activity in treatment of ecchymosis in patients who under went rhinoplasty, the most common facial plastic surgical procedure, researchers at the joint study lead by the University of South Florida independently conducted a review of literature in databases (PubMed, SCOPUS, Embase, Web of Science, and the Cochrane database) from inception to September 2016, included studies that compared postoperative care methods (intervention groups) with no treatment (control group).
According to the final searching of 11 trials satisfied the criteria and guideline with a total of 627 patients, application of topical Arnica showed a significant effect in reduced eyelid ecchymosis during the first 7 days postoperative statistically in compared to the control group.
However, eyelid ecchymosis during the first 24 h postoperatively were statistically decreased in the cold compression group in compared to the control and treatment group.
Patients' questionnaires returned also expressed a strong satisfaction in the tapping application group than in the control group.
Also, the ratio of patient satisfaction was statistically higher in the tapping and Arnica application group than those of control.
Additionally, the analysis also found that surgeons had a significant tendency to decrease intranasal packing in remove pain from the surgery area as the placement was found to associate with more adverse effects in terms of postoperative ecchymosis in compared to non-packing.
Further differentiation to confirm the effectiveness of the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) in reducing postoperative ecchymosis in a select population of healthy volunteers after oculofacial surgery, researchers launched a review to examine the postoperative course, using topical Arnica and Ledum after undergoing common oculofacial procedures, including blepharoplasty, browpexy, and rhinoplasty, in the hands of 4 surgeons at tertiary referral centers from July 1, 2012 to December 31, 2012.
A total of 27 patients (16 females, 11 males) with age range of 18 to 70 years were included in the study.
Selected medical review showed that patients applied bilaterally topical hydrogel pads (OcuMend, Cearna Inc., Chicago, IL) containing Arnica 50 M (10) 50% and Ledum 50 M (10) after surgery through postoperative day(POD) 6 at each postoperative visit.
These results of everyday progression in patients were evaluated by their respective surgeons.
The physician-patient rating score were used to compare each patient's observed healing in each group.
Photographs in each examination also were recorded.
The median duration of follow-up was 7 days, range from 1 to 14 days.
According to the rating of final examination,
* The proportions of patients with markedly accelerated healing were 38.5% (5 of 13), 85.7% (6 of 7), 60.0% (12 of 20), and 51.9% (14 of 27) at POD 1 to 2, 3 to 5, 6 to 8, and overall, respectively.
* The proportions of patients with accelerated healing at the same time points were 15.4% (2 of 13), 14.3% (1 of 7), 30.0% (6 of 20), and 37.0% (10 of 27), respectively.
* The proportion of patients using Arnica/Ledum with markedly accelerated healing was significantly higher than the over all and time point proportion of the other groups at (post operative day) POD 3 to 5 (85.7%), POD 6 to 8 (60.0% ), and overall (51.9%) without inducing any adverse effects.
The findings suggested that combination of Arnica/Ledum were more effective in compared to other treatments.
Dr. Lee HS, the lead author said, "The preliminary results from this study demonstrate that the combination of topical Arnica montana and Rhododendron tomentosum (Ledum palustre) may be effective in reducing postoperative ecchymosis...., after oculofacial surgery".
Taken together, topical Arnica may be used alone or combined with other herbal medicine to accelerate the healing of ecchymosis
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results by Kang JY1, Tran KD, Seiff SR, Mack WP, Lee WW.(PubMed)
(2) The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis by Lee HS1, Yoon HY1, Kim IH1, Hwang SH2.(PubMed)
(3) Is There a Role for Arnica and Bromelain in Prevention of Post-Procedure Ecchymosis or Edema? A Systematic Review of the Literature by Ho D1, Jagdeo J, Waldorf HA.(PubMed)
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