Whole Food Honey, the Natural Antibiotic with No Side Effects

Antibiotics are conventional medicines used for the treatment of microbial infection except for the virus. The aim of the medicines is to kill off the microbial pathogens that cause the disease.

However, epidemiological suggested that antibiotics also kill the good bacterias and cells in the host, leading to weakened body functioning, including the immune system.

Furthermore, overuse of antibiotics over the past many decades has also caused genetic mutation in the bacteria, inducing the bacterial resistance superbugs that have caused a resurgence in some illnesses.

Out of billions of bacteria existed in the world, only a few hundreds have been known to cause infectious diseases. And bacterial pneumonia was probably the leading cause of death among the elderly.

Bacteria after entering the body and found a specific site to incubate, at the time permitted also secret toxins to attack the cells in the area, leading to infection and signs and symptoms of an illness.

Most common symptoms of the acute phase of infection are associated with an immune system response by stimulating the production of pro-inflammatory cytokines with an aim to kill off the pathogens, including fever, malaise, headache, rash.

People with a weakened immune system such as elderly and taking immune suppressive medicines and immature immune system such as infants are prone to the bacterial infection.

Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers.

The liquid is considered one of the healthy food for replacing the use of white sugar and artificial sweetener by many people.

With an aim to find a natural therapy to replace the antibiotic with no side effects, researchers examined the antimicrobial activity and composition of a locally produced Portobello honey (PBH) on three bacteria known to infect wounds, compared to Manuka honey (MH).
The study included selected honeys were tested at four concentrations: 75%, 50%, 10% and 1% (v/v) and compared with untreated control.

According to the tested assays, both honeys at 75% and 50% inhibited the majority of the three bacteria tested. However, the 10% PBH exhibited antimicrobial activity to a lesser extent than 10% MH.

Both honeys were acidic with pH 4, and both produced H2O2 .


The results suggested although both honeys exert the similar antibacterial effects, the MH has significantly higher levels of the polyphenols and antioxidant activity than PBH.

Also, in the comparison of the antibacterial property of other types of honey and Manuka honey, researchers showed that Manuka honey was the most effective against Staphylococcus aureus Oxa R and S. aureus Oxa S with a Minimum Inhibitory Concentration (MIC) of 6% and 7%, respectively, compared to the wild carrot honey with a MIC of 12%.

Furthermore, tested Manuka honey contained the highest content of polyphenols, with 899.09 ± 11.75 mg gallic acid/kg, whereas lavender honey had the lowest, with 111.42 ± 3.54 mg gallic acid/kg.


Dr. the lead scientist wrote in the final report, "The differences between honey samples in terms of antibacterial and antioxidant activity could be attributed to the natural variations in floral sources of nectar and the different locations".


In other words, the antibacterial effect of honeys probably is associated with the levels of polyphenols content.

Taken altogether, honey processed a high amount of polyphenols may be considered antibacterial infection remedies with no side effects, pending to the confirmation of large sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Anti-microbial activity and composition of manuka and portobello honey by Schneider M1, Coyle S, Warnock M, Gow I, Fyfe L. (PubMed)
(2) Antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins by Alzahrani HA1, Alsabehi R, Boukraâ L, Abdellah F, Bellik Y, Bakhotmah BA. (PubMed)

Herbal Artichoke, the Best Anti-Aging Functional Remedy

Skin aging is a natural process which can not be stopped. However, some people may look younger compared to their biological age.

According to the prominent oxidative stress theory, long-term accumulation of cells damage due to overexpression of free radicals in the skin can lead to early skin aging.

The joint study led by the University of Texas Health Science Center at San Antonio suggested, alterations in oxidative damage/stress also play a role in aging. Rodents with resistance to oxidative stress (and in some cases reduced oxidative damage to macromolecules) showed an increased lifespan, compared to oxidative stress control.

Some researchers suggested that genetic preposition may play a critical role in the promotion of delayed aging. Dr. Viviana I Pérez, the lead scientist in the study of free radical theory wrote, "Because only one (the deletion of the Sod1 gene) of the 18 genetic manipulations we studied had an effect on lifespan".

Regardless of free radical or other theories associated with the aging processes, there are many risk factors that can lead to reduced life span and delayed the skin aging process, even in people with a longevity gene.

In other words, long-term unhealthy lifestyle such as excessive alcohol drinking, substances abuse, smoking, physical inactivity not only can reduce the gene effect on longevity but also increase the risk of early skin aging and shorten the proposed life span.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and for the treatment of digestive disorders, abdominal pain gas and bloating, etc.

Researchers on the finding a natural therapeutic which processed antiaging property investigated the anti-age effect of a polyphenolic artichoke extract on endothelial cells.

Injection of the extract showed a significant anti-aging activity by exhibiting the important molecular markers responsible for the microcirculation and vasodilatation of endothelial cells, through its anti-inflammatory function, and protecting the lymphatic vessels from oxidative damage by ROS formation, and enhancing the cellular cohesion by reinforcing the tight junction complex.

In other words, the polyphenolic artichoke extracts exhibited anti-age effect against the skin and subcutaneous tissue damage caused by overexpression of proinflammatory cytokines associated with the production of free radical and depletion of antioxidant enzymes produced by the host.


The anti-aging efficacy was attributed to the combined activity of constituents found in the herbal medicine, including 87% of chlorogenic, 3,5-O-dicaffeoylquinic, and 1,5-O-dicaffeoylquinic acids.

Furthermore, polyphenolic artichoke extract improved the expression of genes involved in anti-aging mechanisms.

On human subjects, an artichoke extract cosmetic formulation also reduced 19.74% of roughness and enhanced 11.45% of elasticity, compared to a placebo cream.

Furthermore, in UVB-induced photoaging, researchers examined antioxidant activity of Cynaropicrin (Cyn), a sesquiterpene lactone, and major bioactive phytochemical in the artichoke.


Cynaropicrin (Cyn) attenuated UVB-induced oxidative stress by activating the AhR-Nrf2-Nqo1 pathway associated with the production of antioxidants and anti-inflammatory factors against oxidative stress.

In other words, in anti-aging perspective, Cyn not only actively inhibited the generation of reactive oxygen species from keratinocytes irradiated with ultraviolet B (UVB), but also the production of proinflammatory cytokines such as interleukin 6 and tumor necrosis factor-α from UVB-treated keratinocytes.

Taken altogether, artichoke processed high amounts of bioactive compounds may be used as a functional antiaging remedy with no side effects, pending to the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
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Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Artichoke Polyphenols Produce Skin Anti-Age Effects by Improving Endothelial Cell Integrity and Functionality by D'Antuono I1, Carola A2, Sena LM3, Linsalata V4, Cardinali A5, Logrieco AF6, Colucci MG7,8, Apone F. (PubMed)
(2) Cynaropicrin attenuates UVB-induced oxidative stress via the AhR-Nrf2-Nqo1 pathway byTakei K1, Hashimoto-Hachiya A1, Takahara M1, Tsuji G1, Nakahara T2, Furue M. (PubMed)
(3) Is the Oxidative Stress Theory of Aging Dead? by Viviana I Pérez,1,2 Alex Bokov,1,3 Holly Van Remmen,1,2,4,6 James Mele,4 Qitao Ran,1,2Yuji Ikeno,1,5,6 and Arlan Richardson. (PMC)

Whole Food Ginger, the Natural Treatment of Premenstrual Syndrome With No Side Effects, according to A Human Study

Scientists may have found a natural kitchen spice for the treatment of premenstrual syndrome symptoms (PMS) with no side effects.

Premenstrual syndrome is a condition caused by the faulty function of the ovaries related to the women's menstrual cycle, due to hormone fluctuation in one to two weeks before menstruation and then declines when the period starts.

PMS affects over 70% to 90% of women in the US compared to a lesser affection to women in Southeast Asia because of the different living style and social structure.

Most common symptoms of PMS include fatigue, fluid retention breast tenderness, acne, sleep disturbances and appetite changes with overeating or food cravings.


PMS can be classified into 4 types, categorizing by the symptoms including1. Anxiety
Anxiety is a common symptom for women with PMS, caused by a hormone imbalance between estrogen and progesterone(1). Most women with PMS is found to have a very high level of estrogen and low levels of progesterone(4) before menstruation.


Withdrawal from chronic exposure to the female sex steroid progesterone (P) may also contribute to the occurrence of PMS anxiety(2).

2. Craving
Some women with PMS may experience the symptom of food craving, caused by an abnormal liver function in carbohydrate synthesis due to dietary habits(6) and abnormal levels of serotonin(10)(8).
Other theories suggest that when a woman under stress before period, she may grasp for everything which makes her feel more comfortable(7).

3. Hyperhydration(11)
Breast tenderness and water retention(12) are always a problem for some women with PMS. Breast tenderness is caused by overproduction of prolactin due to the abnormal function of the pituitary gland(13). Water retention is either caused by overproduction of prolactin-induced renal sodium and potassium excretion(16) or abnormal function of lymphatic function(14)(15).

4. Depression
Researchers found that women with the symptom of depression always have unbalanced levels of estrogen(3) and progesterone as a result of liver abnormal function in fat and protein metabolism(5). This unbalance also induces nervous tension, that causes nervous disorder including depression(3).

Conventionally, selective serotonin reuptake inhibitors (SSRIs), nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics and hormonal contraceptives. are the most common medicine used for the treatment of PMS, depending on the types of symptom.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Researchers on finding a natural compound for the treatment of premenstrual syndrome (PMS), evaluated the effects of ginger on the severity of symptoms of PMS.


The clinical trial, double-blinded work, included 70 participants were randomly allocated to intervention (n = 35) and control (n = 35) groups. All persons suffering from PMS were asked to complete the daily record scale questionnaire for two consecutive cycles before treatment.

According to the returned questionnaire, there were no significant differences between the mean scores of PMS symptoms in the two groups before intervention.

Each participant received two ginger capsules daily from seven days before menstruation to three days after menstruation for three cycles and they recorded the severity of the symptoms by daily record scale in the questionnaire.

By comparing the date 1, 2, and 3 months after intervention, the ginger treatment group showed a significant improvement of the PMS symptoms compared to control.

Dr. Khayat S, and colleagues wrote in the final report, "Based on the results of this study, maybe ginger is effective in the reduction of severity of mood and physical and behavioral symptoms of PMS and we suggest ginger as a treatment for PMS".

Take all together, ginger may be considered a functional alternative for the treatment of premenstrual syndrome (PMS) pending to the confirmation of large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

Sources
(1) Effect of treatment with ginger on the severity of premenstrual syndrome symptoms by Khayat S1, Kheirkhah M2, Behboodi Moghadam Z3, Fanaei H4, Kasaeian A5, Javadimehr M. (PubMed)

Turmeric's Bioactive Compound Curcumin Protects Diabetics Against Diabetic cardiomyopathy

Diabetic cardiomyopathy is a complication found in patients with diabetes associated with reducing the heart function in circulating blood through the body, leading to heart failure and increased the accumulation of fluid in the lungs.

Diabetic cardiomyopathy is classified into different types, depending on the damage that has been affected, including
* Microangiopathy is a disorder that affects small blood vessels, leading to impaired myocardial blood flow reserve.

* Autonomic neuropathy is a disorder that affects the nerves that manage everyday body functions, leading to abnormal blood pressure, heart rate.

* Endothelial dysfunction is a disorder associated with the damage of vascular endothelium. The condition is considered an early event of cardiovascular disease.

Most common causes of diabetic cardiomyopathy are myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia.

At the early stage, most patients with diabetic cardiomyopathy are asymptomatic. However, mild left ventricular diastolic dysfunction with little effect on ventricular filling and concomitant hypertension or coronary artery disease has been found to be the early indication of diabetic cardiomyopathy in patients with diabetes.

Epidemiologically, the most common risk factors that increase the risk of diabetic cardiomyopathy. are insulin resistance, hyperinsulinemia, and hyperglycemia.

Conventionally, as of today, there is no effective treatment of diabetic cardiomyopathy. Medication used for the treatment of the condition is focusing on glycemic control and management of heart failure symptoms.

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

In the urgency to find a potential ingredient for the treatment of diabetic cardiomyopathy(DCM), researchers examined the effect of curcumin on modulating DCM and the mechanisms involved.

The study included experimental diabetic rat model induced by a low dose of streptozotocin(STZ) combined with high energy intake on rats, followed by curcumin orally administrated at a dose of 100 or 200 mg · kg(-1) · d(-1), respectively.

Before treatment of curcumin, induced DCM rats showed a declined systolic myocardial performance associated with myocardial hypertrophy and fibrosis accompanied by the metabolism abnormalities, aberrant myocardial enzymes, and increased AGEs (advanced glycation end products) accumulation.

Increased levels of ROS and depletion of antioxidant enzymes were also found in the rat before pretreatment with curcumin, observed by increased oxidative stress markers.

Futhermore, levels of pro-apoptotic proteins and proinflammatory cytokines were also found to significantly increase in DCM rats.

After injection of curcumin, researchers found that remarkably, the bioactive compound attenuated myocardial dysfunction, cardiac fibrosis, AGEs accumulation, oxidative stress, inflammation and apoptosis in the heart of diabetic rats.


In other words, curcumin protected the heart of DCM rats against the onset of diabetic cardiomyopathy(DCM).

Based on the results, researchers said, "these results suggest that curcumin may have great therapeutic potential in the treatment of DCM, and perhaps other cardiovascular disorders, by attenuating fibrosis, oxidative stress, inflammation, and cell death".

Taken altogether, turmeric processed abundantly bioactive compound curcumin may be considered a supplement for the prevention and treatment of diabetic cardiomyopathy, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy by Zheng J1, Cheng J2, Zheng S3, Feng Q3, Xiao X. (PubMed)
(2) Curcumin alleviates diabetic cardiomyopathy in experimental diabetic rats by Yu W1, Wu J, Cai F, Xiang J, Zha W, Fan D, Guo S, Ming Z, Liu C. (PubMed)

Herbal Artichoke Enhanced Nonpathogenic Intestinal Microflora for the Promotion of Digestive Health

Gut microbiota or gastrointestinal microbiota is the complex community of over 10 trillion microorganisms living in our digestive tracts.

Use of antibiotics, diet, drugs, may alter the composition of the microbiota.

Under the normal condition, in healthy individuals, gut microbiota plays a critical role in the modulation of the immune, metabolic and neurobehavioral traits.

In Immunity, gut microbiota stimulates the immune system protective responses to pathogens and the maintenance of tolerance to innocuous antigens.

In metabolism, gut microbiota improve glucose tolerance, mipoprotein profile and atherosclerotic plaque development.

In neurological disease, gut microbiota improved the neuropsychiatric conditions, including depression, autism and Parkinson’s disease.

In other words, the balanced gut microbiota has a strong impact on the protection of our body against abnormal metabolism, infectious diseases, and loss or death of neurons in the initiation of diseases of the central nervous system.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

Researchers on the finding a natural therapeutics for the improvement nonpathogenic intestinal microflora investigated the dried Jerusalem artichoke(JA) effects on microflora and short-chain fatty acids (SCFA) in the hindgut.in male pigs 1 week fed with JA before slaughter.

The study included 5 experimental groups (n = 11) given different dietary treatments 7 days before slaughter: negative control (basal diet), positive control (basal diet + 9% chicory-inulin), basal diet + 4.1% Jerusalem artichoke, basal diet + 8.1% Jerusalem artichoke and basal diet + 12.2% Jerusalem artichoke.

Increasing levels of Jerusalem artichoke to entire male pigs reduced skatole, a mildly toxic compound in digesta from colon and in feces and level of Clostridium perfringens, type of bad bacterias in the gut in both colon and rectum.

Furthermore, injection of JA also increased the total amount of SCFA (linear, P < 0.05), acetic acid (linear, P < 0.05) and valerianic acid (linear, P < 0.01) produced by the friendly bacteria in your gut in feces.

JA improved intestinal microflora by reducing skatole levels through decreasing in C. perfringens and the increase in SCFA with a subsequent reduction in pH.

Taken altogether, artichoke may be considered a functional formula for the improvement of the intestinal microflora, with no side effects, pending to the validation of larger sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Feeding Jerusalem artichoke reduced skatole level and changed intestinalmicrobiota in the gut of entire male pigs by Vhile SG1, Kjos NP, Sørum H, Overland M. (PubMed)
(2) The effects of inulin, dried Jerusalem artichoke tuber and a multispecies probiotic preparation on microbiota ecology and immune status of the large intestine in young pigs by Barszcz M1, Taciak M1, Skomiał J. (PubMed)

Whole Food Ginger Suppresses Rheumatoid Arthritis

Scientists may have found a kitchen pungent spice for the treatment of rheumatoid arthritis with no side effects, according to studies.

Rheumatoid Arthritis is a chronic disorder characterized by inflammation of the flexible (synovial) joints and tissues and organs in the body.

The disease affects more women than men and generally occurs after the ages of 40, causing the diminished quality of life of many elders.


According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affects over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.

Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.


A cross-sectional population-based study of 1042 patients with rheumatoid arthritis showed that RA patients had an increased risk of death from various causes.


Patient with rheumatoid arthritis (RA) often associates to valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot. The kinematic and kinetic gait changes in rheumatoid arthritis (RA) are the result of a significant reduction in joint motions, joint moments, such as decreased hip flexion-extension range, hip abduction, knee flexion-extension range,...


Long-term bone damage and the prolonged onset of the disease can induce deformities of hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.


The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations physically that can affect daily living and quality of life.

Furthermore, rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with RA.


Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in early stage of rheumatoid arthritis.

Dr. Motl RW and Dr. McAuley E. in the assessment of chronic diseases said, " The rationale and the associated onset of chronic disease conditions that influence function, disability, and quality of life (QOL) are embedded in the "Graying of America""(29), including patients with RA.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Scientists in seeking a potent natural ingredient or compound for the treatment of rheumatoid arthritis investigated ginger's traditional use as an anti-inflammatory against RA in Chinese and Ayurvedic medicine.

In joint swelling in an animal model of rheumatoid arthritis and streptococcal cell, wall-induced researchers compared crude ginger extract and a fraction containing only gingerols and their derivatives.

According to the assays, both extracts were efficacious in preventing joint inflammation.

However, the crude dichloromethane extract, containing essential oils and more polar compounds, was more efficacious in preventing both joint inflammation and destruction, compared to the fraction.


The results strongly suggested the use of ginger extract for the prevention of joint inflammation and destruction in RA.


Dr. Funk JL and colleagues at the University of Arizona wrote, " these data document a very significant joint-protective effect of these ginger samples and suggest that nongingerol components are bioactive and can enhance the antiarthritic effects of the more widely studied gingerols.


In order to reveal more information about ginger anti-RA property, researchers evaluated the anti-inflammatory effects of ginger's other secondary metabolites, the essential oils (GEO), containing terpenes in female Lewis rats with SCW-induced arthritis.


Injection of GEO (28 mg/kg/d ip) prevented chronic joint inflammation, without altering the initial acute phase of joint swelling and granuloma formation at sites of SCW deposition in the liver.


Compared to pharmacologic doses of 17-β estradiol (200 or 600 μg/kg/d sc), GEO elicited the same pattern of anti-inflammatory activity by its phytoestrogenic activity.

Based on the findings, Dr.Funk JL, the lead scientist wrote again in the final report, "ginger's anti-inflammatory properties are not limited to the frequently studied phenolics, but may be attributable to the combined effects of both secondary metabolites, the pungent-tasting gingerols and as well as its aromatic essential oils".


Take all together, ginger processed a high amount of bioactive compounds and secondary metabolites may be considered a functional alternative for prevention and treatment of RA, pending to the confirmation of large sample size and multicenter human study.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.


Sources
(1) Anti-Inflammatory Effects of the Essential Oils of Ginger (Zingiber officinaleRoscoe) in Experimental Rheumatoid Arthritis by Funk JL1, Frye JB1, Oyarzo JN1, Chen J1, Zhang H2, Timmermann BN. (PubMed)
(2) Comparative effects of two gingerol-containing Zingiber officinale extracts on experimental rheumatoid arthritis by Funk JL1, Frye JB, Oyarzo JN, Timmermann BN. (PubMed)
(3) Most Common Disease of the elder: The Clinical Trials and Studies of musculoskeletal disorders(MSDs) - Rheumatoid Arthritis: The Signs and Symptoms by Kyle J. Norton

Herbal Artichoke, the Anti Skin Cancer Herbal Remedy

Scientists may have found a natural whole food for the treatment of skin cancer with no side effects, according to studies.

Skin cancer is a medical condition caused by cell growth irregularly in the skin tissue. Most cases of skin cancer begin in the cells on the surface of the inner lining of the skin due to the alternation of DNA.

The causes of skin cancer are unknown. However, researchers do know that personal and family history, fair skin, long-term exposure sun UVB are some prevalent risk factors of the disease.

In the Western world, the common factor linking a person to skin cancer is cumulative sun exposure induced basal cell and squamous cell skin cancer.

According to the statistics, approximately 90 percent of nonmelanoma skin cancers are associated with exposure to ultraviolet (UV) radiation from the sun and basal cell carcinoma (BCC) is the most common form of skin cancer.

In the US, sadly to say that approximately 4.3 million cases of BCC are diagnosed each year, causing the death of 3000 people.

Believe or not, more people are diagnosed with skin cancer each year in the U.S. than all other cancers combined.

Dr. Caroline Chang, in the concerns of widespread, nake skin exposure to the sun in the Summer in the risk of skin cancer, wrote, "Although personal melanoma risk factors are well established,... The desire to be tan, which has its roots in the medical profession, retains its popularity today despite evidence linking UV exposure to skin cancer".

The findings strongly suggested that the general public although has been warned that UV exposure is associated with skin cancer risk but some most people still have a desire to be tan.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.

On finding a natural ingredient for the treatment of skin cancer with no side effects, researchers investigated the methanol extract of the flowers of artichoke (Cynara cardunculus) exhibited remarkable antitumor activity in an in vivo two-stage carcinogenesis test in mice.

Mice selected to the study were induced skin cancer by the injection of 12-O-tetradecanoyl phorbol-13-acetate (TPA).

The active fraction of the methanol extract including four triterpene alcohols and their corresponding acetates showed inhibitory effects on TPA-induced inflammation (1 microg/ear) with a 50% inhibitory dose of 0.50-0.91 micromol/ear.


Furthermore, the anti-skin cancer activity of 2 taraxastane-type hydroxy triterpenes, taraxasterol and faradiol, isolated from the flowers of Compositae plants Cynara scolymus (artichoke) and Chrysanthemum morifilolium (chrysanthemum), also demonstrated a similar effect in the previous study against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.


More precisely, these compounds inhibited the tumor-promoting effect of TPA (1 microgram/mouse) on skin tumor formation following initiation with 7,12-dimethylbenz[alpha]anthracene (50 micrograms/mouse).

Taken altogether, artichoke processed numbers of the bioactive compound may be considered a functional remedy for the prevention and treatment of skin cancer, pending to the results from a larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Inhibitory effect of the flowers of artichoke (Cynara cardunculus) on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin by Yasukawa K1, Matsubara H, Sano Y. (PubMed)
(2) Inhibitory effect of taraxastane-type triterpenes on tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin by Yasukawa K1, Akihisa T, Oinuma H, Kaminaga T, Kanno H, Kasahara Y, Tamura T, Kumaki K, Yamanouchi S, Takido M. (PubMed)