Wednesday, February 8, 2017

Hormone Testosterone and Endometrium

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

                      Hormone Testosterone

Testosterone is a steroid hormone found abundantly in the male with characteristics of muscles, hair, strength, bone mass, etc.. In women, testosterone produced by by the ovaries and adrenal glands with only 10% that the male counterpart but females are more sensitive to the hormone.

     Hormone Testosterone and Endometrium

Hormone estrogen is best known for its function in stimulating the thickening of the endometriun to provide a suitable environment for implanation of fertilized egg if conceived with assisting of progesterone. Less known testosterone also have certain influences in that process, according to the study of an open, randomized clinical study with parallel group comparison was performed in the Women's Health Research Unit at a university hospital, posted in PubMed. Thirty-one postmenopausal women were given oral estradiol valerate (2 mg daily) or estradiol valerate in combination with testosterone undecanoate (40 mg every 2 days) for 3 months, researchers found that Expressions of AR and ER-beta were stronger in glands of the endometrium of postmenopausal women after treatment withtestosterone added to estrogen than after estrogen alone. In contrast, expressions of ER-alpha and progesterone receptors were up-regulated in the endometrium with estrogen-alone treatment, whereas these expressions were less increased in glands after combined treatment. These data indicate that testosterone is involved in the regulation of sex hormone receptor expression in the postmenopausalendometrium and may therefore influence endometrial proliferation and differentiation.

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