Saturday, April 22, 2017

Hormone Serotonin or 5-hydroxytryptamine (5-HT): levels in early postnatal life and autism spectrum disorders (ASDs)

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

          Hormone Serotonin or 5-hydroxytryptamine (5-HT) 

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter derived from tryptophan, primarily found in the gastrointestinal (GI) tract, platelets, and in the central nervous system (CNS). In Gut, serotonin regulates intestinal movements, in CNS, it regulates mood, appetite, sleep, memory and learning, etc.

     Hormone Serotonin or 5-hydroxytryptamine (5-HT) levels in early postnatal life and autism spectrum disorders (ASDs) 

In the study to examine two inbred mouse strains (C57BL/6 and BALB/c) with respect to these phenomena of transient brain overgrowth in early postnatal life and elevated 5-HT (serotonin) levels in blood platelets (platelet hyperserotonemia). The BALB/c strain is less social and exhibits some other autistic-like behaviors, found that in mice, autistic-like shifts in the brain and periphery may be associated with less autistic-like behaviors. Importantly, they suggest that consistency among behavioral, anatomical, and physiological measures may expedite the validation of new and previously proposed mouse models of autism, and that the construct validity of models should be demonstrated when these measures are inconsistent(33).

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