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Monday, April 3, 2017

Hormone Serotonin or 5-hydroxytryptamine (5-HT)and vasoconstrictor synergism

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

          Hormone Serotonin or 5-hydroxytryptamine (5-HT) 

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter derived from tryptophan, primarily found in the gastrointestinal (GI) tract, platelets, and in the central nervous system (CNS). In Gut, serotonin regulates intestinal movements, in CNS, it regulates mood, appetite, sleep, memory and learning, etc.


     Hormone Serotonin or 5-hydroxytryptamine (5-HT) and vasoconstrictor synergism

In the study to observe the Contractile synergism between serotonin (5-hydroxytryptamine, 5-HT) and other vasoconstrictor substances in a number of peripheral and cerebrovascular blood vessels, found that this phenomenon may play an important role in certain pathological states such as hypertension, peripheral vascular disease, and coronary spasm. Tthe synergism between serotonin and other vasoconstrictor agents and focus on a recently described type of vasoconstrictor synergism in which precontraction with a non-5-HT receptor agonist yields an enhanced contractile response to serotonin which is mediated by previously inactive or "silent" 5-HT receptor subtypes(14).



Sources
(14) http://www.ncbi.nlm.nih.gov/pubmed/9585103

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