Celery and Celery Seeds in Suppression of Arthritis

Celery may be used as natural food therapy in suppressed Arthritis Diseases in the induction of acute and chronic painful or inflammatory symptoms, some scientists suggested.

Arthritis is a class of over 100 medical conditions, affecting people of all ages, sexes, and races.

In an aging population, the most common cause of arthritis is the degeneration of cartilage, the slick, cushioning surface on the ends of bones that has bee worn away, causing bone rubs against bone, in the induction of pain, swelling, and stiffness.

Depending to the severity of osteoarthritis, patients may experience symptoms that surround the joints in hands, knees, hips, and spine, such as pain in the joint during or after movement, muscle and feet tenderness, stiffness, loss of flexibility. ... and grating sensation.

The other most common types of arthritis are Rheumatoid arthritis (RA) that is a long-term autoimmune disorder, inducing warm, swollen, and painful joints.

According to statistic, approximately, 50 million adults and 300,000 children have some forms or types of arthritis.

The CDC statistic from 2013–2015, stated that an estimated 54.4 million US adults (22.7%) annually have ever been told by a doctor that they have some form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia(4).

The prevalent risk factor is also depended to where you live. For example, the percentage of adults with arthritis varies by state, ranging from 17.2% in Hawaii to 33.6% in West Virginia in 2015(4).r

The John Hopkins arthritis center suggested, " Data from 32,322 adults in 11 states from the 1998 Behavioral Risk Factor Surveillance Survey (BRFSS), a health survey given annually in the United States, indicates that adults with arthritis report significantly greater HRQL impairment compared to adults without arthritis"(5).

Celery is a species of Apium graveolens, belongings to the family Apiaceae. The food or vegetable is cultivated all around the globe for commercial profits.


Celery can grow to 1/2 m tall with stalks (leaf on the top) arranging in a conical shape joined at a common base.

According to a recent study, celery seed extract (CSE) processed a strong effect in suppressing arthritis symptoms in a model of polyarthritis without interaction to medication intake. in comparison to aspirin, ibuprofen, and naproxen

Dr. Powanda MC, the lead researcher said, " unlike many dietary supplements, the available data suggest that CSE does not significantly affect the p450 enzyme systems( function in interaction with medication intake) and thus is less likely to alter the metabolism of drugs the individual may be taking"

The over-counter (OTC) oral remedies for arthritis and rheumatism classified celery seed extracts are more effective than ibuprofen in the anti-arthritic assay without causing gastric bleeding.

However, treatment of arthritis is ranged from almost zero to highly effective depending on a certain class of products.

Therefore, for maximum effect, types of celery seed extract (CSE) chosen should only be prescribed by related field specialist.

In support of the above differentiation, the Prince of Songkla University conducted an experimenter by applying A. graveolens (AGE), a bioactive compound isolated from celery seed against liver oxidative stress in adjuvant-induced arthritis rat model.

The results showed that oral administration of AGE (250, 500, and 1,000 mg/kg) for 24 consecutive days reduced symptoms of arthritis through reduced liver oxidative stress and enhanced liver antioxidant properties including host antioxidant enzymes glutathione peroxidase (GPx) and superoxide dismutase (SOD).

Taking all together, intake of celery may be effective in ameliorated symptoms of arthritis through binding to the expression of proinflammatory cytokines.

However, further data collection on large sample size and multi-center clinical studies performed with human consumption during the course of the investigation will be necessary to complete the picture of celery and its bioactive compounds protective effect against arthritis possibilities.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Celery Seed and Related Extracts with Antiarthritic, Antiulcer, and Antimicrobial Activitie by Powanda MC, Whitehouse MW, Rainsford KD. (PubMed)
(2) Over the counter (OTC) oral remedies for arthritis and rheumatism: how effective are they? by Whitehouse MW1, Roberts MS, Brooks PM.( PubMed)
(3) Effects of Apium graveolens Extract on the Oxidative Stress in the Liver of Adjuvant-Induced Arthritic Rats bySukketsiri W1, Chonpathompikunlert P2, Tanasawet S3, Choosri N1, Wongtawatchai T3. (PubMed)
(4) Arthritis-Related Statistics(CDC)
(5) Arthritis and Health-related Quality of Life by Kevin Fontaine, Ph.D. (John Hopskins Arthritis Center)