Brain ischemia is a condition caused by insufficient blood flow to the brain to meet metabolic demand, leading to irreversible brain damage in severe cases.
In other words, brain ischemia-induced the death of neurons of the affected tissues.
A neuron or nerve cell made of a cell body (also called soma), dendrites and an axon, is a cell in the nervous system that carries electrical impulses.
Neurons are core components of the brain, spinal cord and peripheral nerves that play an essential role to process and transmit information.
The function of neurons can be classified into 3 types
* The sensory neurons found within the nervous system that convert external stimuli from the organism's environment into internal electrical impulses. In other words, sensory neurons are activated by sensory input from the environment, including physical input of sound, touch, heat, or light.
*The motor neurons transmit impulses from the spinal cord to skeletal and smooth muscles,. In other words, motor neurons directly control all of the muscle movements.
* The interneurons connect the motor and sensory neurons. In other words, the interneurons transfer signals between sensory and motor neurons.
Brain ischemia can be classified into
* Focal ischemia is a condition caused by damage to a specific region of the brain; and
* Global ischemia is a condition of damage that affects the wide areas of brain tissue, leading to symptoms of impairments in vision, body movement, and speaking.
Dr. Taoufik E, the lead scientist, in the study of the neuron death following a stroke, may help to develop effectively neuroprotective strategies, said, "The two principal models for human stroke are induced in rodents either by global or focal ischemia. In both cases, blood flow disruptions limit the delivery of oxygen and glucose to neurons causing ATP reduction and energy depletion, initiating excitotoxic mechanisms that are deleterious for neurons".
And, "Both in vitro and in vivo studies, targeting a single death mechanism either by the inhibition of death-inducing molecules or the overexpression of antiapoptotic components in neurons, have shown tremendous neuroprotective potential".
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding the potential and natural remedy for the treatment of post cerebral ischemia injury,
evaluated the effects of Angelica Sinensis extract [Dang Gui (DG)] administered before 60min of middle cerebral artery occlusion followed by 3 days of reperfusion.
According to the results of DG intraperitoneally administered at a dose of 0.25 g/kg, 0.5 g/kg (DG-0.5g), or 1 g/kg (DG-1g) 30 min before the onset of cerebral ischemia
* DG-0.5g and DG-1g pretreatment effectively attenuated cerebral infarct and improved neurological deficits.
* DG-0.5g and DG-1g pretreatment significantly reduced proteins associated with the expression inflammatory response after injury, depredation, and apoptosis of neurons and pathways involved in the reduction of oxidative stress.
Furthermore, DG-0.5g and DG-1g pretreatment also protected the neurons against additional damage induced by cerebral ischemia injury by inhibiting the production of pro-inflammatory cytokines and
cell apoptosis due to oxygen deficiency and improving the kinases in neurotransmission.
More precisely, DG-0.5g and DG-1g pretreatment provided neuroprotective effects against astrocyte-mediated cerebral infarction by activating angiogenic and anti-apoptotic signaling.
Based on the findings, Angelica Sinensis in a dose depend-manner may be used as a functional remedy for the protection of further neuron damage in patients with cerebral ischemia injury, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Angelica sinensis Exerts Angiogenic and Anti-apoptotic Effects Against Cerebral Ischemia-Reperfusion Injury by Activating p38MAPK/HIF-1[Formula: see text]/VEGF-A Signaling in Rats by Cheng CY1,2, Ho TY1, Hsiang CY3, Tang NY1, Hsieh CL4,5, Kao ST1, Lee YC. (PubMed)
(2) Ischemic neuronal damage by Taoufik E1, Probert L. (PubMed)
Friday, May 8, 2020
Thursday, May 7, 2020
Herbal Coltsfoot(Tussilago farfara) Protects the Lung Against Tuberculosis (TB)
The lung is a vital organ located near the backbone on either side of the heart with major functions to inhale oxygen from the air to the bloodstream that nourishes the body cells and exhale carbon dioxide from the bloodstream.
Other functions of the lung are to maintain the right levels of pH, filter out blood clots, protect the heart against shock, infection, and speech.
Tuberculosis (TB) is a contagious disease caused by bacteria called Mycobacterium tuberculosis.
The bacteria attacked the lung tissue, leading to the significantly reduced function of the lung in the inhaling and exhaling.
The disease is also found to cause major damage to other parts of the body.
According to statistics, 25% of the world's population is infected with TB. In 2016, 10.4 million people around the world became sick with the disease-inducing the death of 1.7 million people.
The most common signs and symptoms of TB are associated with reduced lung function, including coughing that lasts a long period of time, coughing up blood, chest pain, particularly in breathing or coughing, fatigue, fever, night sweats, and chills.
Some patients may also experience symptoms of unintended weight loss.
Conventionally, the length of treatment of TB depending on the severity of the disease takes longer compared to other infections with at least six months of antibiotics intake, including Isoniazid, Rifampin (Rifadin, Rimactane) and Ethambutol (Myambutol).
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound that processes antitubercular activity, researchers examined the effect of Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis.
In Mycobacterium tuberculosis H37Rv, according to the tested analysis, the ethyl acetate extract of Tussilago farfara displayed antitubercular activity with a MIC of 62.5 μg/mL.
The anti-tuberculosis property of Tussilago farfara against the Mycobacterium tuberculosis H37Rv was attributed to the compounds including a mixture of β sitosterol/stigmasterol (4), trans-caffeic acid (7), kaempferol (8), quercetin (9), kaempferol-3-O-glucoside (10), loliolide (11), a (4:1) mixture of p-coumaric acid/4-hydroxybenzoic acid (12), p-coumaric acid (13). in the extract.
In compound comparison, the best anti-tuberculosis activity was observed in the p-coumaric acid (13) (MIC 31.3 μg/mL or 190.9 μM) alone and in mixture with 4-hydroxybenzoic acid (12) (MIC 62.5 μg/mL).
Based on the findings, researchers aid, "The above results provide for the first time some scientific evidence to support, to some extent, the ethnomedicinal use of Arctium lappa and Tussilago farfara as traditional antitubercular remedies.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of tuberculosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents by Zhao J1, Evangelopoulos D2, Bhakta S2, Gray AI1, Seidel V. (PubMed)
Other functions of the lung are to maintain the right levels of pH, filter out blood clots, protect the heart against shock, infection, and speech.
Tuberculosis (TB) is a contagious disease caused by bacteria called Mycobacterium tuberculosis.
The bacteria attacked the lung tissue, leading to the significantly reduced function of the lung in the inhaling and exhaling.
The disease is also found to cause major damage to other parts of the body.
According to statistics, 25% of the world's population is infected with TB. In 2016, 10.4 million people around the world became sick with the disease-inducing the death of 1.7 million people.
The most common signs and symptoms of TB are associated with reduced lung function, including coughing that lasts a long period of time, coughing up blood, chest pain, particularly in breathing or coughing, fatigue, fever, night sweats, and chills.
Some patients may also experience symptoms of unintended weight loss.
Conventionally, the length of treatment of TB depending on the severity of the disease takes longer compared to other infections with at least six months of antibiotics intake, including Isoniazid, Rifampin (Rifadin, Rimactane) and Ethambutol (Myambutol).
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belongings to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of years to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound that processes antitubercular activity, researchers examined the effect of Arctium lappa and Tussilago farfara extracts for activity against Mycobacterium tuberculosis.
In Mycobacterium tuberculosis H37Rv, according to the tested analysis, the ethyl acetate extract of Tussilago farfara displayed antitubercular activity with a MIC of 62.5 μg/mL.
The anti-tuberculosis property of Tussilago farfara against the Mycobacterium tuberculosis H37Rv was attributed to the compounds including a mixture of β sitosterol/stigmasterol (4), trans-caffeic acid (7), kaempferol (8), quercetin (9), kaempferol-3-O-glucoside (10), loliolide (11), a (4:1) mixture of p-coumaric acid/4-hydroxybenzoic acid (12), p-coumaric acid (13). in the extract.
In compound comparison, the best anti-tuberculosis activity was observed in the p-coumaric acid (13) (MIC 31.3 μg/mL or 190.9 μM) alone and in mixture with 4-hydroxybenzoic acid (12) (MIC 62.5 μg/mL).
Based on the findings, researchers aid, "The above results provide for the first time some scientific evidence to support, to some extent, the ethnomedicinal use of Arctium lappa and Tussilago farfara as traditional antitubercular remedies.".
Taken altogether, coltsfoot may be considered a remedy for the treatment of tuberculosis, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The antitubercular activity of Arctium lappa and Tussilago farfara extracts and constituents by Zhao J1, Evangelopoulos D2, Bhakta S2, Gray AI1, Seidel V. (PubMed)
Wednesday, May 6, 2020
Herbal Coltsfoot(Tussilago farfara) Processes Anti-Inflammatory Activity
Inflammation is a natural defense of the immune system that protects the body against the insult from the foreign invasion.
Acute inflammation occurs quickly that lasts a few days or weeks. Most cases of acute inflammation-induced tissue damage are healed themselves after all pathogens are killed off.
However, if the immune system can not completely eradicate all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.
Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.
Any inflammation that lasts more than 8 weeks is considered chronic inflammation.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Anti-inflammation is a process that inhibits the pro-inflammatory cytokines without affecting the immune system activity against pathogens.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of diseases associated with inflammation, researchers examined the anti-inflammatory effect of Tussilagone (FTF), isolated from the flower of buds of Tussilago farfara (Compositae).
The study included compounds 1-4 chlorogenic acid (1), 3,5-dicaffeoylquinic acid (2), 3,4-dicaffeoylquinic acid (3), and 4,5-dicaffeoylquinic acid (4) isolated from ETE and their mixture was determined by spectral analysis given to mice orally in a ratio of 5:28:41:26 as in EtE) at doses of 10 and 20 mg/kg once daily for 3 days. All mixture showed a significant antitussive effect by exhibiting anti-inflammatory effects against cough frequency by 61.7%.
Compared to other compounds, compound 2 was the most potent to enhance the phenol red secretion by 35.7% in alleviating inflammation.
Compound 4 showed the strongest effect to inhibit the leukocytosis by 49.7%.
Based on the findings, researchers said, "The caffeoylquinic acids and their mixture, exhibiting significant antitussive, expectorant, and anti-inflammatory effects, could be considered as the main effective ingredients of FTF, and they may act in a collective and synergistic way".
Taken altogether, coltsfoot may be considered a remedy for the treatment of disease associated with inflammatory disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara by Wu QZ1, Zhao DX1, Xiang J1, Zhang M1, Zhang CF1, Xu XH. (PubMed)
Acute inflammation occurs quickly that lasts a few days or weeks. Most cases of acute inflammation-induced tissue damage are healed themselves after all pathogens are killed off.
However, if the immune system can not completely eradicate all invaders in the acute phase of infection, it will compromise, leading to chronic low-grade inflammation, a major cause of cardiovascular disease, arthritis, and diabetes.
Chronic inflammation is a low-grade inflammation caused by the inability of the immune system to eliminate the invasive pathogens that occurred in the acute phase of infection.
Any inflammation that lasts more than 8 weeks is considered chronic inflammation.
Believe it or not, worldwide, 3 of 5 death are results from chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes.
In the US, chronic inflammatory diseases affect more than 50 million Americans each year.
Anti-inflammation is a process that inhibits the pro-inflammatory cytokines without affecting the immune system activity against pathogens.
Diseases associated with low-grade inflammation include diabetes and cardiovascular.
Coltsfoot(Tussilago farfara) is a perennial herbaceous plant, genus Tussilago, belonging to the family Asteraceae, native to Europe and Asia. The herb has been used over thousands of year to treat asthma, various coughs, bronchial congestion, respiratory disorders, headaches and obstruction in the nasal passage, etc.
On finding a potential compound for the treatment of diseases associated with inflammation, researchers examined the anti-inflammatory effect of Tussilagone (FTF), isolated from the flower of buds of Tussilago farfara (Compositae).
The study included compounds 1-4 chlorogenic acid (1), 3,5-dicaffeoylquinic acid (2), 3,4-dicaffeoylquinic acid (3), and 4,5-dicaffeoylquinic acid (4) isolated from ETE and their mixture was determined by spectral analysis given to mice orally in a ratio of 5:28:41:26 as in EtE) at doses of 10 and 20 mg/kg once daily for 3 days. All mixture showed a significant antitussive effect by exhibiting anti-inflammatory effects against cough frequency by 61.7%.
Compared to other compounds, compound 2 was the most potent to enhance the phenol red secretion by 35.7% in alleviating inflammation.
Compound 4 showed the strongest effect to inhibit the leukocytosis by 49.7%.
Based on the findings, researchers said, "The caffeoylquinic acids and their mixture, exhibiting significant antitussive, expectorant, and anti-inflammatory effects, could be considered as the main effective ingredients of FTF, and they may act in a collective and synergistic way".
Taken altogether, coltsfoot may be considered a remedy for the treatment of disease associated with inflammatory disease, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antitussive, expectorant, and anti-inflammatory activities of four caffeoylquinic acids isolated from Tussilago farfara by Wu QZ1, Zhao DX1, Xiang J1, Zhang M1, Zhang CF1, Xu XH. (PubMed)
Tuesday, May 5, 2020
Herbal Artichoke, the Natural and Potential Treatment of Diabetes
Diabetes is a medical and condition caused by insufficient insulin entering the bloodstream to regulate the glucose. The disease is either caused by cells in the pancreas that died off or receptor sites clogged up by fat and cholesterol.
The hallmark of diabetes is hyperglycemia associated with abnormally high blood glucose. Early detection of autoantibodies against beta cell markers can be helpful for the treatment of type 1 diabetes.
In type 2 diabetes, diagnosed abnormal metabolites as potential markers were found to benefit the severity of various clinical complications.
The exact causes of type 1 diabetes are unknown. Researchers cannot explain why the immune system in some patients choose to destroy the insulin-producing (islet, or islets of Langerhans) cells in the pancreas.
Although there are many risk factors associated with the onset of type 2 diabetes such as genetic preposition and lifestyle, some researchers suggested that the incidence of obesity in the Western world may have a strong implication on type 2 diabetes developing.
Dr. Abdullah S Al-Goblan, the lead scientist, in the investigation of the mechanism linking diabetes mellitus and obesity, wrote, "The pathogenesis in the development of diabetes is based on the fact that the β-islet cells of the pancreas are impaired, causing a lack of control of blood glucose".
And, "The development of diabetes becomes more inevitable if the failure of β-islet cells of the pancreas is accompanied by insulin resistance. Weight gain and body mass are central to the formation and rising incidence of type 1 and type 2 diabetes".
Therefore, if you are obese, your risk of type 1 and 2 are higher compared to healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the course to find a natural remedy for the treatment of type 2 diabetes, researchers examined the Jerusalem artichoke (JA) effects on lipid disturbance and insulin resistance in an animal model.
Wistar rats selected to the study were fed a control diet, a 60 % fructose-enriched diet (FRU), or an FRU with 10 % JA (n 6-7) for 4 weeks.s
Rats group treated with FRU resulted in IR and hepatic triacylglycerol (TAG) accumulation.
Additional injection of 10% JA not only reverses the alternation IR and hepatic triacylglycerol (TAG) accumulation but decreased the expression of proteins associated with the production of inflammatory cytokines induced by FRU.
The results of JA efficacy were attributed to modulate the expression of proteins, malic enzyme 1 (Me1) involved in lipid synthesis, decorin (Dcn) related to the development of fibrosis and other genes associated with inflammation.
The results clearly suggested that through molecular mechanisms, JA processes a significant effect in the prevention of type 2 diabetes and nonalcoholic liver disease.
Dr, the lead scientist wrote in the final report, "10 % JA supplementation may be beneficial for the prevention of the onset of these diseases (type 2 diabetes and nonalcoholic liver disease) diseases".
In order to reveal more information about artichoke anti-diabetes activity, researchers evaluated the effect of supplementation with a Jerusalem artichoke and fermented soybean powder mixture on blood glucose and oxidative stress levels.
The additional randomized, double-blinded, placebo-controlled study included 60 subjects with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or newly diagnosed type 2 diabetes.
The selected subjected were randomly assigned to either a group that ingested 40 g of a Jerusalem artichoke and fermented soybean powder mixture (19.45 g each) daily or a group that received a placebo for 12 weeks.
Subjects treated with the Jerusalem artichoke and fermented soybean powder mixture showed a significant reduction of the levels of fasting glucose, glucose at 60 min, and glucose areas under the response curve (AUC).
Furthermore, the group treated with the mixture also improved the insulin resistance, according to assay.
The mixture also was found to inhibit the expression of oxidative stress observed by the changes (Δ) in the urinary 8-epi-PGF2α index.
Moreover, the glucose at 60 min, 120 min, and AUC, FFAs at 0 min, and AUC of the mixture treated group demonstrated a potential anti-diabetes property compared to the non-treatment group.
Taken altogether, JA may be considered a functioning remedy for the prevention and treatment of type 2 diabetes, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats by Chang WC1, Jia H2, Aw W2, Saito K2, Hasegawa S3, Kato H. (PubMed)
(2) The effects of Jerusalem artichoke and fermented soybean powder mixture supplementation on blood glucose and oxidative stress in subjects with prediabetes or newly diagnosed type 2 diabetes by Ahn HY1, Kim M1, Seo CR2, Yoo HJ3, Lee SH4, Lee JH. (PubMed)
(3) Review of diabetes: identification of markers for early detection, glycemic control, and monitoring clinical complications by Wu JT. (PubMed)
(4) Mechanism linking diabetes mellitus and obesity by Abdullah S Al-Goblan,1 Mohammed A Al-Alfi,1 and Muhammad Z Khan. (PMC)
The hallmark of diabetes is hyperglycemia associated with abnormally high blood glucose. Early detection of autoantibodies against beta cell markers can be helpful for the treatment of type 1 diabetes.
In type 2 diabetes, diagnosed abnormal metabolites as potential markers were found to benefit the severity of various clinical complications.
The exact causes of type 1 diabetes are unknown. Researchers cannot explain why the immune system in some patients choose to destroy the insulin-producing (islet, or islets of Langerhans) cells in the pancreas.
Although there are many risk factors associated with the onset of type 2 diabetes such as genetic preposition and lifestyle, some researchers suggested that the incidence of obesity in the Western world may have a strong implication on type 2 diabetes developing.
Dr. Abdullah S Al-Goblan, the lead scientist, in the investigation of the mechanism linking diabetes mellitus and obesity, wrote, "The pathogenesis in the development of diabetes is based on the fact that the β-islet cells of the pancreas are impaired, causing a lack of control of blood glucose".
And, "The development of diabetes becomes more inevitable if the failure of β-islet cells of the pancreas is accompanied by insulin resistance. Weight gain and body mass are central to the formation and rising incidence of type 1 and type 2 diabetes".
Therefore, if you are obese, your risk of type 1 and 2 are higher compared to healthy weight individuals.
Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.
The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas and bloating, etc.
In the course to find a natural remedy for the treatment of type 2 diabetes, researchers examined the Jerusalem artichoke (JA) effects on lipid disturbance and insulin resistance in an animal model.
Wistar rats selected to the study were fed a control diet, a 60 % fructose-enriched diet (FRU), or an FRU with 10 % JA (n 6-7) for 4 weeks.s
Rats group treated with FRU resulted in IR and hepatic triacylglycerol (TAG) accumulation.
Additional injection of 10% JA not only reverses the alternation IR and hepatic triacylglycerol (TAG) accumulation but decreased the expression of proteins associated with the production of inflammatory cytokines induced by FRU.
The results of JA efficacy were attributed to modulate the expression of proteins, malic enzyme 1 (Me1) involved in lipid synthesis, decorin (Dcn) related to the development of fibrosis and other genes associated with inflammation.
The results clearly suggested that through molecular mechanisms, JA processes a significant effect in the prevention of type 2 diabetes and nonalcoholic liver disease.
Dr, the lead scientist wrote in the final report, "10 % JA supplementation may be beneficial for the prevention of the onset of these diseases (type 2 diabetes and nonalcoholic liver disease) diseases".
In order to reveal more information about artichoke anti-diabetes activity, researchers evaluated the effect of supplementation with a Jerusalem artichoke and fermented soybean powder mixture on blood glucose and oxidative stress levels.
The additional randomized, double-blinded, placebo-controlled study included 60 subjects with impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or newly diagnosed type 2 diabetes.
The selected subjected were randomly assigned to either a group that ingested 40 g of a Jerusalem artichoke and fermented soybean powder mixture (19.45 g each) daily or a group that received a placebo for 12 weeks.
Subjects treated with the Jerusalem artichoke and fermented soybean powder mixture showed a significant reduction of the levels of fasting glucose, glucose at 60 min, and glucose areas under the response curve (AUC).
Furthermore, the group treated with the mixture also improved the insulin resistance, according to assay.
The mixture also was found to inhibit the expression of oxidative stress observed by the changes (Δ) in the urinary 8-epi-PGF2α index.
Moreover, the glucose at 60 min, 120 min, and AUC, FFAs at 0 min, and AUC of the mixture treated group demonstrated a potential anti-diabetes property compared to the non-treatment group.
Taken altogether, JA may be considered a functioning remedy for the prevention and treatment of type 2 diabetes, pending to the confirmation of larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Beneficial effects of soluble dietary Jerusalem artichoke (Helianthus tuberosus) in the prevention of the onset of type 2 diabetes and non-alcoholic fatty liver disease in high-fructose diet-fed rats by Chang WC1, Jia H2, Aw W2, Saito K2, Hasegawa S3, Kato H. (PubMed)
(2) The effects of Jerusalem artichoke and fermented soybean powder mixture supplementation on blood glucose and oxidative stress in subjects with prediabetes or newly diagnosed type 2 diabetes by Ahn HY1, Kim M1, Seo CR2, Yoo HJ3, Lee SH4, Lee JH. (PubMed)
(3) Review of diabetes: identification of markers for early detection, glycemic control, and monitoring clinical complications by Wu JT. (PubMed)
(4) Mechanism linking diabetes mellitus and obesity by Abdullah S Al-Goblan,1 Mohammed A Al-Alfi,1 and Muhammad Z Khan. (PMC)
Monday, May 4, 2020
Herbal Chaste Tree Berry Normalizes Hormones in women Menstrual Cycle by Increased Levels of Progesterone
Chaste Tree berry may be used as a functional food in regulated production of progesterone in balancing steroid hormone in women menstrual cycle, a renowned institute study suggested
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Progesterone is a sex hormone with various mechanisms, including women's menstrual cycle, pregnancy, embryogenesis......
According to the Royal Melbourne Institute of Technology-University, Vitex may have a function similar to the conventional medicine, fluoxetine, in stimulated production of increasing mid-luteal progesterone and 17β-oestradiol levels in women menstrual cycle.
In the review of databases of 8 literature collection, Vitex extracts showed a significant effect in women's health. In the aspect of premenstrual syndrome, the extract improves psychological symptoms such as depression, anxiety,... through progesterone regulation.
Dr. Deborah Brauser, the author of the article of "Progesterone, Anxiety Affect Premenstrual Dysphoric Disorder" said, "As a gynecologist, I believe PMDD is driven by the female sex hormone progesterone," said Dr. Sundström Poromaa, adding that there is very little progesterone during the follicular phase".
Flavonoid glycosides, orientin and apigenin 3, 8-di-C-glycosides in addition to iridoid compound, aucubin isolated from the ethanolic extract of Vitex agnus-castus fruits, also displayed an increased production of progesterone hormone by observation of plasma progesterone of women with 0.6 and 1.2 g kg(-1) per body weight (b.w.) doses.
The study also addressed the hormone progesterone may have a directed effect in increased uterine weight of ovariectomized rats in comparison to that of the control group.
Dr. Jillian Stansbury, the researcher of the women herbs for men said, "Consumption of Vitex fruits by female chimpanzees as part of their natural diets has been found to dramatically increase progesterone levels in the urine, indicating an overall progesterone effect.34 One hypothesis is that reduced LH allows the follicle-stimulating hormone to dominate and can lead to decreased estrogen and testosterone and a relative increase in progesterone".
Furthermore, the contribution of the herb in the improved concentration of progesterone in the luteal phase, may increase the chance of pregnancy, as the total of 37 women with oligomenorrhea and 30 women with amenorrhea received 50 drops of Phyto Hypophyson L, a Vitex agnus castus-containing homeopathic preparation or placebo 3 times a day over 3 months or 3 cycles report.
Promisingly, intake of the Vitex agnus castus-containing homeopathic preparation expressed spontaneous menstruation, improved concentration of progesterone in the luteal phase, shortening of the cycle, earlier ovulation, and pregnancy in 38 out of 67 women.
Taking together, chemical constituents found in Chaste tree berry expressed a strong activity in an increased chance of pregnancy and normalized hormone aspects in women menstrual cycle with progesterone and other hormones regulation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) Progesterone, Anxiety Affect Premenstrual Dysphoric Disorder by Deborah Brauser(Medscape)
(3) Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruitsgrowing in Egypt by Ibrahim NA1, Shalaby AS, Farag RS, Elbaroty GS, Nofal SM, Hassan EM.(PubMed)
(4) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury
(4) [The efficacy of the complex medication Phyto-Hypophyson L in female, hormone-related sterility. A randomized, placebo-controlled clinical double-blind study].[Article in German]by Bergmann J1, Luft B, Boehmann S, Runnebaum B, Gerhard I.(PubMed)
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of years as an aphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
Progesterone is a sex hormone with various mechanisms, including women's menstrual cycle, pregnancy, embryogenesis......
According to the Royal Melbourne Institute of Technology-University, Vitex may have a function similar to the conventional medicine, fluoxetine, in stimulated production of increasing mid-luteal progesterone and 17β-oestradiol levels in women menstrual cycle.
In the review of databases of 8 literature collection, Vitex extracts showed a significant effect in women's health. In the aspect of premenstrual syndrome, the extract improves psychological symptoms such as depression, anxiety,... through progesterone regulation.
Dr. Deborah Brauser, the author of the article of "Progesterone, Anxiety Affect Premenstrual Dysphoric Disorder" said, "As a gynecologist, I believe PMDD is driven by the female sex hormone progesterone," said Dr. Sundström Poromaa, adding that there is very little progesterone during the follicular phase".
Flavonoid glycosides, orientin and apigenin 3, 8-di-C-glycosides in addition to iridoid compound, aucubin isolated from the ethanolic extract of Vitex agnus-castus fruits, also displayed an increased production of progesterone hormone by observation of plasma progesterone of women with 0.6 and 1.2 g kg(-1) per body weight (b.w.) doses.
The study also addressed the hormone progesterone may have a directed effect in increased uterine weight of ovariectomized rats in comparison to that of the control group.
Dr. Jillian Stansbury, the researcher of the women herbs for men said, "Consumption of Vitex fruits by female chimpanzees as part of their natural diets has been found to dramatically increase progesterone levels in the urine, indicating an overall progesterone effect.34 One hypothesis is that reduced LH allows the follicle-stimulating hormone to dominate and can lead to decreased estrogen and testosterone and a relative increase in progesterone".
Furthermore, the contribution of the herb in the improved concentration of progesterone in the luteal phase, may increase the chance of pregnancy, as the total of 37 women with oligomenorrhea and 30 women with amenorrhea received 50 drops of Phyto Hypophyson L, a Vitex agnus castus-containing homeopathic preparation or placebo 3 times a day over 3 months or 3 cycles report.
Promisingly, intake of the Vitex agnus castus-containing homeopathic preparation expressed spontaneous menstruation, improved concentration of progesterone in the luteal phase, shortening of the cycle, earlier ovulation, and pregnancy in 38 out of 67 women.
Taking together, chemical constituents found in Chaste tree berry expressed a strong activity in an increased chance of pregnancy and normalized hormone aspects in women menstrual cycle with progesterone and other hormones regulation.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Sources
(1) Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials by van Die MD1, Burger HG, Teede HJ, Bone KM.(PubMed)
(2) Progesterone, Anxiety Affect Premenstrual Dysphoric Disorder by Deborah Brauser(Medscape)
(3) Gynecological efficacy and chemical investigation of Vitex agnus-castus L. fruitsgrowing in Egypt by Ibrahim NA1, Shalaby AS, Farag RS, Elbaroty GS, Nofal SM, Hassan EM.(PubMed)
(4) WOMEN’S HERBS” FOR MEN By Editor1 Posted November 8, 2010
In Botanical Medicine, Endocrinology, Fertility, Men's Health, Nature Cure, Oncology, Dr Jillian Stansbury
(4) [The efficacy of the complex medication Phyto-Hypophyson L in female, hormone-related sterility. A randomized, placebo-controlled clinical double-blind study].[Article in German]by Bergmann J1, Luft B, Boehmann S, Runnebaum B, Gerhard I.(PubMed)
Sunday, May 3, 2020
Herbal Comfrey(Symphytum officinale L.) Promotes Bone Density in Vivo
Bone is a hard whitish tissue making up the skeleton in humans which provides a framework for the attachment of muscles and other tissues.
Bone density is the amount of bone mineral in bone tissue. Loss of bone density is found to induce osteoporosis.
Bone density is measured by the young adult bone density mean within 1 standard deviation (+1 or −1). The negative T-score is an indication of loss or lower bone density and the T-score of −2.5 or lower is an indication of osteoporosis.
Risk factors of losing bone density include gender, (women are more likely to develop osteoporosis compared to men) the increase in age, race, (African Americans have both lower rates of bone density loss and osteoporosis), family history.
People with low bone mass accompanied by progressive bone density loss over time are associated with an increased risk of developing osteoporosis.
Low bone mass is a risk factor of osteoporosis, The condition may also increase the incidence of bone fracture if it is accompanied by other risk factors.
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
It is a widespread degenerative disease of skeletal joints and often associated with senescence in the vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries.
If you experience symptoms of lower back pain, loss of height over time, a stooped posture, easy bone fracture, neck and back pain,..., you may have osteoporosis.
Truly, bone diseases in children have been found to affect normal growth and development that can lead to weakness and/or deformity.
Comfrey is a perennial plant in the genus of Symphytum, belonging to the family Boraginaceae, native to Europe. It has been used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relieve pain and swollen, treat circulation issues, reduce cholesterol, etc.
On finding a potential compound for the treatment of osteoporosis, researchers investigated the effect of Symphytum officinale (Comfrey) in homeopathic potency (6cH), on the removal torque and radiographic bone density around titanium implants, inserted in rats tibiae.
Selected rats induced loss of bone density in the study were randomized into a group of control and group treated by S. officinale 6cH.
According to the evaluation at 7, 14, 28, and 56 days post-implantation, removal torque of the implants rats treated the S. Officinale 6cH showed to enhance bone formation around the micro-implants at 14 days.
At 56 days, the radiographic bone density was higher in the treated group, compared to control.
Based on the findings, researchers said, " S. Officinale 6cH enhances, principally at the early stages of osseointegration, bone formation around titanium implants in rats' tibiae, based on the radiographic and mechanical analysis.".
Taken altogether, Comfrey combined with other herbal medicine may be considered a remedy for the promotion of bone density, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Homeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in rats by Spin-Neto R1, Belluci MM, Sakakura CE, Scaf G, Pepato MT, Marcantonio E Jr. (PubMed)
Bone density is the amount of bone mineral in bone tissue. Loss of bone density is found to induce osteoporosis.
Bone density is measured by the young adult bone density mean within 1 standard deviation (+1 or −1). The negative T-score is an indication of loss or lower bone density and the T-score of −2.5 or lower is an indication of osteoporosis.
Risk factors of losing bone density include gender, (women are more likely to develop osteoporosis compared to men) the increase in age, race, (African Americans have both lower rates of bone density loss and osteoporosis), family history.
People with low bone mass accompanied by progressive bone density loss over time are associated with an increased risk of developing osteoporosis.
Low bone mass is a risk factor of osteoporosis, The condition may also increase the incidence of bone fracture if it is accompanied by other risk factors.
Osteoporosis is a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time.
It is a widespread degenerative disease of skeletal joints and often associated with senescence in the vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries.
If you experience symptoms of lower back pain, loss of height over time, a stooped posture, easy bone fracture, neck and back pain,..., you may have osteoporosis.
Truly, bone diseases in children have been found to affect normal growth and development that can lead to weakness and/or deformity.
Comfrey is a perennial plant in the genus of Symphytum, belonging to the family Boraginaceae, native to Europe. It has been used in herbal and traditional medicine to ease excessive bleeding or on open wounds, relieve pain and swollen, treat circulation issues, reduce cholesterol, etc.
On finding a potential compound for the treatment of osteoporosis, researchers investigated the effect of Symphytum officinale (Comfrey) in homeopathic potency (6cH), on the removal torque and radiographic bone density around titanium implants, inserted in rats tibiae.
Selected rats induced loss of bone density in the study were randomized into a group of control and group treated by S. officinale 6cH.
According to the evaluation at 7, 14, 28, and 56 days post-implantation, removal torque of the implants rats treated the S. Officinale 6cH showed to enhance bone formation around the micro-implants at 14 days.
At 56 days, the radiographic bone density was higher in the treated group, compared to control.
Based on the findings, researchers said, " S. Officinale 6cH enhances, principally at the early stages of osseointegration, bone formation around titanium implants in rats' tibiae, based on the radiographic and mechanical analysis.".
Taken altogether, Comfrey combined with other herbal medicine may be considered a remedy for the promotion of bone density, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Homeopathic Symphytum officinale increases removal torque and radiographic bone density around titanium implants in rats by Spin-Neto R1, Belluci MM, Sakakura CE, Scaf G, Pepato MT, Marcantonio E Jr. (PubMed)
Saturday, May 2, 2020
Herbal Angelica Improves the Mitochondrial Functioning
Mitochondria are power generators of the cell found abundantly in the liver and play a critical role in converting oxygen and nutrients to energy for the cell's metabolisms.
Mitochondrial permeability transition (MPT) and the mitochondrial generation of oxidative stress have been found to initiate hepatic mitochondrial dysfunction caused by hepatocellular necrosis and apoptosis.
Where, the protein mitochondrial permeability transition pore is formed in the inner membrane of the mitochondria under certain pathological conditions, including stroke, leading to symptoms of lethargy, hypotonia, vomiting, poor suck, and seizures.
Mitochondria bioenergetics play a critical for normal cell function and human health. The alternation of mitochondrion DNA has been found to induce a number of diseases.
More precisely, the genetic proposition has been found to alter the process of mitochondria in converting oxygen and food to energy in some people. Acquired mitochondrial dysfunction has been found in patients with Alzheimer’s disease, muscular dystrophy, Lou Gehrig’s disease, diabetes, and cancer. including mitochondrial myopathy, diabetes mellitus, and deafness.
Most common symptoms of mitochondrial dysfunction include poor growth muscle weakness, muscle pain, low muscle tone, exercise intolerance, vision and/or hearing problems
learning disabilities, delays in development, mental retardation depending on the location of the infected cells.
According to the statistics, 1 in 5,000 individuals has a genetic mitochondrial disease. Each year, about 1,000 to 4,000 children in the United States are born with mitochondrial disease.
Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.
The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.
On finding a natural compound for the treatment of diseases associated with mitochondrial dysfunction, the researchers examined the effects of Danggui Buxue Tang (DBT) on mitochondrial respiration of cultured H9C2 cardiomyoblasts.
According to the chemical analysis, DBT exerted a strong antioxidant and radical scavenging activity against oxidative stress, and protective effect in tert-butyl hydroperoxide (tBHP)-treated cultured cardiomyoblast.
Furthermore, the transcript expressions of peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PCG-1α) and other genes, relating to mitochondria biogenesis were enhanced by the injection of the decoction.
Moreover, cultured cardiomyoblasts showed an improvement of total status under DBT treatment through a number of mechanisms, including an increase of basal respiration, proton leak, non-mitochondria, and adenosine triphosphate (ATP) production by stimulating the mitochondrial biogenesis and DNA replication
Taken altogether, Herbal Angelica may protect the mitochondrial functioning, pending to larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Danggui Buxue Tang, a Chinese Herbal Decoction Containing Astragali Radix and Angelicae Sinensis Radix, Modulates Mitochondrial Bioenergetics in Cultured Cardiomyoblasts by Kwan KKL1,2, Huang Y1,2, Leung KW1,2, Dong TTX1,2, Tsim KWK. (PubMed)
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