Wednesday, May 15, 2019

Herbal Ginger, the Potential and Natural Antihypothermia Functional Food, According to Scientists

Hypothermia is a medical emergency due to the loss of heat faster than the body can produce, leading to a temperature that lowers than the normal low body temperature.

In other words, if your body temperature falls below 95 F (35 C) with no signs of reverse, you may have hypothermia.

Most case of hypothermia in North American is associated with long-term exposure to cold temperature due to inadequate clothing. According to the statistics, from 1999 to 2011, hypothermia caused the death of a total of 16,911 people in the United States associated with exposure to excessive natural cold.

However, people with hypothyroidism, drug abuse, infection such as septic are also found to induce hypothermia.

Symptoms of hypothermia are depending on the stages of the condition.

In the mild stage (from 90°F to 95°F (32.2°C to 35°C)), patients may only have symptoms of high blood pressure, shivering, rapid breathing, and heart rate,... due to the constricted blood vessels.

In the moderate stage (from 82.4°F to 90°F (28°C to 32.2°C)), patients may experience symptoms of irregular heartbeat, a slower heart rate and breathing, lower level of consciousness, due to not enough supply to the organs needs.


In the severe case, (less than 82.4°F (28°C)), patients may have loss of consciousness, heart failure, pulmonary edema, and cardiac arrest, due to organs failure.


Regardless of the stage, hypothermia is a life-threatening condition, please call 911 right the way.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

Scientists on finding a natural remedy for the protection of our body temperature against hypothermia investigated the ginger extract employing a solid dispersion (SD) approach, against hypothermia on a rat model.

In chemicals analysis, GE/SD exhibited improved dissolution behavior of the major active ingredients in GE and 6-gingerol (6G) and 8-gingerol (8G), with levels of dissolution 12- and 31-fold higher than that of GE, respectively.

Orally administered GE/SD (30 mg of GE/kg) inhibited ethanol-evoked hypothermia by improving oral absorption of 6G and 8G.


Storages of ginger were found slightly reduced levels of 6G and 8G by degradation without affecting the functions of 6G and 8G against the hypothermic activity.

Oral administration of GE (300 mg/kg) and GE/SD (100 mg of GE/kg), significantly elevated the relative bioavailabilities of 6G and 8G in GE/SD by 5.0- and 5.8-fold compared those in GE against the hypothermia in tested subjects.

The results suggested that solid dispersion (SD) may be used to improve GE function of hypothermia by enhancing the levels of bioactive compounds.


Taken all together, ginger processed bioactive compound 6-gingerol (6G) and 8-gingerol (8G) with or without employing a solid dispersion (SD) approach may be considered a functional remedy for the prevention and treatment of hypothermia with no side effects, pending to the confirmation of large sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Ginger Extract-Loaded Solid Dispersion System with Enhanced Oral Absorption and Antihypothermic Action by Sato H1, Ogino M1, Yakushiji K1, Suzuki H1, Shiokawa KI2, Kikuchi H2, Seto Y1, Onoue S1. (PubMed)

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