Recent study by a renowned institute suggested that Chaste tree berry may have a potential in improved male infertility as a contraceptive functional food.
Infertility is condition of inability of a couple to conceive after 12 months of unprotected sexual intercourse. It affects over 5 millions couple alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seeks help from professional specialist.
Chaste tree berry is a species of Vitex agnus-castus, genus Vitex, belonging to the family Lamiaceae, native to the Mediterranean region, used in herbal medicine for thousands of year as anaphrodisiac herb and considered as Queen herb in treating menstrual problems and discomforts.
According to the Indian Institute of Technology Roorkee, flavonoid-rich seed extracts of Chaste tree berry oral administration, promoted sperm numbers dwindled and slackness in their motility of that may impede fertility.
In extract fed male rats with four different concentrations after 15 days, treatment of all concentrations displayed a drop in weight with a marginal chance of fructose in seminal vesicles and epididymal alpha-glucosidase, probably involved in reducing the fertilizing ability of the spermatozoa.
Dr. Das S, the lead author said, "the seedextracts of V. negundo interfere with male reproductive function without producing adverse toxicity in other vital organs".
Interestingly, the same extract used in testing the antiandrogenic effects in dog model, administrated dogs showed a antagonized androgen action of exogenous testosterone on the male reproductive system, reducing sexual design and impeded sperm production and mobility.
In the duration of treatment of 30 and 60 days, the extract causes a disruption of the latter stages of spermatogenesis with devoid of spermatozoa passed through epididymides.
Furthermore, when the extract used combination with testosterone propionate, a ester of propionic acid,. dogs maintained the viability of spermatozoa with significantly increased the cellular heights of epididymides in compared non treatment dogs.
Taking together, chaste tree berry intake may be acted as infertile substance for male to prevent unwanted pregnancy of female partner, but the use of the herbal medicine for contraceptive purpose should only recommended by herbalists.
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Sources
(1) Reproduction in male rats is vulnerable to treatment with the flavonoid-rich seed extracts of Vitex negundo by Das S1, Parveen S, Kundra CP, Pereira BM.(PubMed)
(2) Antiandrogenic effects of a flavonoid-rich fraction of Vitex negundo seeds: a histological and biochemical study in dogs by Bhargava SK1(PubMed)
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