Herbal Cayenne, The Best Whole Herb Medicine for Prevention and Treatment of Liver Cancer

Capsaicin (8-methyl-N-vanillyl-6-nonenamide), a major ingredient found in cayenne may be used as a supplement for protection against liver cancer.

According to a recent study by the Duksung Women's University, oral administration of Capsaicin inhibited HepG2 human hepatoblastoma cells, through its antioxidants activities in the induction of apoptosis in the oxidase-mediated generation of ROS.

Other studies insisted that cayenne exerted protection against liver cancer, is the result of inhibition of cancer cell proliferation, migration and invasion of tumors, and induced tumors to radiotherapy and chemotherapy.

Cayenne is also known as Cayenne Pepper, a red, hot chili pepper, belonging to Capsicum annuum, the family Solanaceae, native to subtropical and tropical regions, used in traditional medicine to increases metabolism, enhance circulatory system and stomach and the intestinal tract, adjust blood pressure, lower LDL cholesterol and triglycerides, treat frostbite, muscles, arthritis, rheumatism, low back pain, strains, sprains, bruises, and neuralgia, etc.

Liver cancer is a condition of out of controlled growth of hepatocellular cells in the liver. Since the organ is a soft tissue with less nerve, most liver cancer patients are diagnosed in the later stage of cancer. According to the statistic, liver cancer remains the fifth most common malignancy in men and the eighth in women worldwide.
Hepatocellular carcinoma (HCC) is a common form of primary liver cancer.

In a 4-wk feeding of B6C3F1 mice at 6 wk of age, oral intake of the cayenne group expressed not the only bodyweight but also reduced hypoglycemia and cells involved in the generation of liver cancer.


Dr. Teel RW, author of the research said, " At concentrations of 25, 50, and 100 microM, capsaicin inhibited the biotransformation of (Aflatoxin B1(AFB1) produced by hepatitis viral) by modifying Phase I hepatic enzyme activity ( induced damage and injure of the liver) "

Furthermore, in the inhibition of toxical metabolism, capsaicin also possessed antimutagenic and anticarcinogenic properties against many types of cancer.

Taking all together, cayenne may process the anti liver cancer effect, but a large quantity intake should only be prescribed by herbalists.


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Sources
(1) Spices for Prevention and Treatment of Cancers by Zheng J1, Zhou Y2, Li Y3, Xu DP4, Li S5, Li HB6,7.(PubMed)
(2) Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells by Lee YS1, Kang YS, Lee JS, Nicolova S, Kim JA.(PubMed)
(3) A 4-week feeding study of ground red chilli (Capsicum annuum) in male B6C3F1 mice by Jang JJ1, Devor DE, Logsdon DL, Ward JM.(PubMed)
(4) Effects of capsaicin on rat liver S9-mediated metabolism and DNA binding of aflatoxin by Teel RW1.(PubMed)