Tuesday, October 11, 2016

Chinese Herbal Medicine Therapy: Sha Yuan Zi (Semen Astragali Complanati)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

           Sha Yuan Zi (Semen Astragali Complanati)

Sha Yuan Zi is also known as Flatstem Milkvetch Seed. The sweet and warm herb has been used in TCM to treat spermatorrhea, premature ejaculation, achy loin, dizziness, frequent urination, enuresis, vagina discharge, neurasthenia, etc., as it tonifies the Kidneys, preserves the Essence, nourishes the Liver,improves vision, etc. by enhancing the functions of liver and kidney channels.

1. Astragaloside
2. Soyasaponin I
3. [3-O-alpha-L-rhamnopyrannosyl-(1-->2)-beta-D-sylopyranosyl (1-->2)-Beta-D-glucuronopyranosyl-soyasapogenol B 22-O-beta-D-glucopyranoside]
4. [3-Omega-alpha-L-rhamnopyranosyl-(1-->2) - beta-D-galactopyranosyl - (1-->2) -beta-D-glucuropyranosyl-soyasapogenol-B-22-O-beta-D-glucopyranoside]
5. Etc.

Health Benefits
1. Radioprotective effect
In the aim to investigate the radioprotective effect of flavonoids extracted from the seeds of Astragalus complanatus R.Br. (FAC) and their protective mechanism against radiation damage, showed that FAC increased the survival rate of mice and made the damaged organ injured by (60)Co γ-irradiation recovered to normal appearance with the mechanism of enhancing immune function and blood-producing function in vivo. The molecule mechanism of FAC against radiation is involved in the reduction of DNA injury and mutation in vitro. Eleven monomers of the FAC were analyzed by HPLC. These results seem to support the use of FAC in relieving radiation damage(1).
2. Hepatocarcinoma
In the study to investiagte to evaluate the effects of these flavonoids from Astragalus complanatus (FAC) on human hepatocarcinoma cell viability and apoptosis and to investigate its mechanisms of action in SMMC-7721 cells, indicated that FAC may play an important role in tumor growth suppression by inducing apoptosis in human hepatocarcinoma cells via mitochondria-dependent and death receptor-dependent apoptotic pathways(2).
3. Hypertensive effects
In the aim to investigate effects of total flavonoid fraction of Asttragalus complanatus on blood pressure in conscious spontaneously hypertensive rats(SHR) and hemodynamics in anesthetized SHR, researchers found that total flavonoid fraction of Asttragalus complanatus (100, 200 mg.kg-1) could decrease blood pressure of conscious SHR(decreasing 7.1%, P < 0.05 and 9.3%, P < 0.01 respectively). Meanwhile, there was no significant change in heart rate(HR). R Br (200 mg.kg-1) could decrease total peripheral resistance (TPR) (decreasing 20%, P < 0.05) but did not influence the cardiac output(CO) and heart rate in anesthetized SHR(3).
4. Etc.

Side Effects
1. Do not use the herb in case of spermatorrhea, frequent urination due to kidney Yang deficiency
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

(1) http://www.ncbi.nlm.nih.gov/pubmed/21075176
(2) http://www.ncbi.nlm.nih.gov/pubmed/19429375
(3) http://www.ncbi.nlm.nih.gov/pubmed/12776592

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