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Wednesday, October 5, 2016

Herbal Therapy: The Aloe Vera gels effects on Lung cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
                                         Aloe Vera

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is also one of many popular herb studied in scientific ways with some conflicted results.


                                                      Lung cancer

Lung cancer is defined as a condition of the abnormal growth of the cells in the lung's tissue. Most common form of primary lung cancers are derived from epithelial cells. In Us, Lung cancer is the leading cause of cancer deaths, causing 158,683 people deaths, including 88,329 men and 70,354 women, according to 2007 statistic.

The Ingredients
The main areas of chemical constituents of Aloe vera include: Aloe-Emodin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

The benefits
Aloe-emodin has been studied extensively through our scientific community for their effects against cancer including the study of induced apoptosis in lungcarcinoma cell lines CH27 (human lung squamous carcinoma cell) by breaking of DNA strands (DNA ladders and sub-G(1) formation) and regulating of the expression of Bcl-2 family proteins (a suppressor of apoptosis). In the study of the effects of aloe-emodin-induced cell death in the human lung nonsmall cell carcinoma cell line H460, aloe-emodin involved the regulating apoptotic cell deaththrough the a class of mitogen-activated protein kinases(p38). These results suggested that aloe-amodin found in ALOE VERA may be a potential agent for preventing and treating lung cancer.

The Side effects
People with gallbladder disease may want to consult with their doctor before using because of the herb stimulating gallbladder contraction effect.


References
(1) Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma.


Lee HZ, Hsu SL, Liu MC, Wu CH.(PubMed)
(2) Signaling pathway for aloe-emodin-induced apoptosis in human H460 lungnonsmall carcinoma cell. by Yeh FT, Wu CH, Lee HZ(PubMed)


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