Friday, October 7, 2016

Chinese Herbal Medicine Therapy: Sang Ji Sheng (Ramulus Loranthi)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

          Sang Ji Sheng (Ramulus Loranthi)

Sang Ji Sheng is also known as mulberry mistletoes. The bitter and neutral herb has been used in TCM as diuretic, lowering blood pressure, sedative, antiviral agent and to dilate coronary arteries, improve volume of circulation, etc., as it expels Wind-Damp, tonifies the Liver andthe Kidney, strengthens the sinews and bone, prevents miscarriage, etc. by enhancing the functions liver and kidney channels.

1. Quercetin
2. Avicularin
3. Triterpenes
4. Oleanolic acid
5. Flavonoids
6. (+)-catechin; Rutin; Isoquercitrin
7. 7-O-galloyl-(+)-catechin; Quercetin-3-O-(6″-galloyl)-(-D-glucoside
8. Quercetin-3-O-(6″-galloyl)-(-D-galactoside
9. Quercetin-3-O-(-D-glucuronide
10. Etc.

Health Benefits
1. Fatty acid synthase (EC, FAS) inhibition and body weight reduction
In the study to determine the inhibitory characteristics and kinetic parameters of extracts of parasitic loranthus [Taxillus chinensis (DC.) Danser]. The parasitic loranthus extracts (PLE) inhibits FAS reversibly and irreversibly and with an IC50 value of 0.48 microg/ml, appears to be the most potent inhibitor reported to date. PLE contains various potent inhibitors and may react with different sites on FAS. The irreversible inhibition exhibits a time-dependent biphasic process including a speedy fast-phase during the initial several minutes. The fast-phase inhibition seems to be caused by some potent but low-concentration component(s) in the extracts(1)
2. Refractory polycystic ovary syndrome (PCOS)
In the clinical effect of traditional Chinese medicine Bushen Houxue (BSHX)(dodder seed 20 g, prepared rehmannia root 10 g, mulberry mistletoe 20 g, epimedium 15 g, psoralea fruit 10 g, solomonseal rhizome 10 g, honeylocust thorn 15 g, peach kernel 10 g, pleione bulbocodioides 10 g, red sage root 20 g, and licorice root 6 g,) method combined with ultrasound-guided follicle aspiration (MFA) in treating refractory polycystic ovary syndrome (PCOS) found that BSHX method combined with MFA is a safe and effective treatment for refractory PCOS, with few trauma. The combined usage of Chinese herbal medicine could significantly reduce dosage of HMG used for promoting follicle and the production of multiple mature follicles, thus to avoid the risk of ovarian hyperstimulating syndrome (OHSS)(2).
3. Anticancer effects
In the study to compare the anticancer effects of flavonoids extracts of Scurrula parasitica from different host trees in vitro. 80% ethanol extracts of S. parasitica parasitizing on Nernium indicum, Morus alba, Opsmanthus fragrans, and Sapindus mulorossi were purified by polyamides column chromatography, and the eluates of 30%, 50%, 70% and 90% ethanol were mixed as flavonoids extracts. Extract of S. parasitica parasitizing on N. indicum (NISPEX) was the most sensitive to HL-60 cells of the 4 different host trees, the IC50 value being 0.60 mg x L(-1); and extract of S. parasitica parasitizing on M. alba took the second place, the IC50 value, being 2.49 mg x L(-1); extract of S. parasitica parasitizing on O. fragrans had no effectiveness as high as 50 mg x L(-1) concentration. NISPEX induced HL-60 cell apoptosis and inhibited the cell proliferation in dose and time-dependent manner. Cell cycles were arrested at G0-G1 phase after treated with NISPEX(3).
4. Diabetes
In the study of the Effects of oral administration of some herbal extracts on food consumption and blood glucose levels in normal and streptozotocin-treated diabetic rats, showed that Tapinanthus nyasicus leaf, Ficus thoningii bark, Solanum incanum fruit, and Morus alba leaf extracts decreased weekly food consumption throughout the 5-week study period. Similar results were obtained for the groups treated with metformin or glibenclamide. However, food consumption was increased by S. incanum root, Aloe chabaudii leaf, or Allium sativum bulb extracts, and this was associated with high prevalence of diarrhea(4).
5. Etc.

Side Effects
1. Overdose can cause vomiting, diarrhea, etc.
2. Etc.

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