Monday, October 17, 2016

Chinese Herbal Therapy – Shan Zhu Yu (Fructus Corni Officinalis)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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          Shan Zhu Yu (Fructus Corni Officinalis) 

Shan Zhu Yu is also known as Cornus fruit. The sour, acrid, slightly warm, not toxic herb has been used in TCM to treat impotence, spermatorrhea, instant sweating, sore or week knees, chronic lower back pain, frequent urination, incontinence, excessive bleeding during menstrual period, etc., as it tonifies the Liver and the Kidneys, benefits the Liver and the Kidneys, strengthens, etc. by enhancing the functions of liver and kidney channels.

1. Morroniside
2. Loganin
3. Sweroside
4. Iridoid glycosides
5. Tannins
6. Isoterchebin
7. Tellimagrandin
8. 1.2.6-Tri-O-galloy-β-D-glueoside
9. Cornusiin
10. Urosolie acid
11.Tartarie acid
12. Cornuside
13. Etc.

Health Benefits
1. Allergic asthma
In the study to investigate the anti-asthmatic effects of CF and their underlying mechanism, by examining the influence of CF on the development of pulmonary eosinophilic inflammation and airway hyperresponsiveness in a mouse model of allergic asthma, showed that the therapeutic effects of CF in asthma are mediated by reduced production of Th2 cytokines (IL-5), eotaxin, and OVA-specific IgE and reduced eosinophil infiltration(1).
2. Insulin-dependent diabetes mellitus
In the study of isolated 12 compounds from Corni fructus including three flavonoids, two iridoid glycosides, three phenolic compounds, and two triterpenoids, together with cornuside (11) and 2-butoxybutanedioic acid (12). Chemical structures were identified by (1)H, (13)C NMR, DEPT, COSY, HSQC, and HMBC spectral analyses, indicated that the glucose uptake efficiency, messenger (m)RNA expression of phosphoenolpyruvate carboxykinase (PEPCK), and prevention of cytokine-mediated cytotoxicity in the presence of test agents were evaluated. While CH and CB significantly increased glucose uptake from muscle, compounds 3 and 8, each at 50 μM, significantly suppressed PEPCK mRNA expression. Finally, compound 5, at 50 and 100 μM, effectively attenuated β-cell death. In conclusion, those compounds could contribute to the antihyperglycemic and β-cell-protective actions of Corni fructus against diabetes mellitus(2).
3. Anti-inflammatory and analgesic effects
In the investigation of the analgesic effect of corni fructus in mice, showed that the extract suppressed the acetic acid-induced writhing response in mice. The aqueous extract of corni fructus exerts anti-inflammatory and analgesic effects by suppressing COX-2 and iNOS expression through the down-regulation of NF-kappaB binding activity(3).
4. Etc.

Side Effects
1. Not to use the herb in cases liver yang ascending or difficulty in urination due to damp-heat
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consulting with the related field specialist.
3. Etc.

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