Friday, August 26, 2016

Most Common Diseases of Ages of 50 Plus: Cancers - What is Cancer

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Among elderly men, cancer of the prostate (451 per 100,000), the lung (449 per 100,000) and the colon (176 per 100,000) make up around half of all diagnosed cancers. Prostate cancer is around 22 times more frequent among elderly men than among younger men. The corresponding most frequent cancers among elderly women, making up 48% of all malignant cancers, are breast (248 per 100,000), colon (133 per 100,000), lung (118 per 100,000) and stomach cancer (75 per 100,000), According to the Danish Cancer Society, Institute of Cancer Epidemiology(PubMed)

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

The growth of normal cells
Under normal circumstance, cell growth is a natural process without even notice, everyday millions of cell grow to replace millions of dead cells and to keep our body in balance and healthy.
Sometimes, acceleration of cells growth is necessary to prevent further damage to the body organs, such as cut, injure, etc., but after fulfilling their purposes, the growth of cells are back to normal rate again due to our body growth inhibitors. Unfortunately, skin cells sometimes overgrow while healing, leading to scar to the skin.

The primary tumor; size and growth
A primary tumor or original tumor is a tumor that is at the original site where it first arose where tumor progression began and proceeded to yield a cancerous mass. Some types of cancer can begin in several place, such as lymphomas and leukemias. Most cancers can not be detected until they formed a lump as little as a grape. A cancer cells need 42 doubling before itcan produce enough cancer cells to cause death.

How cancer cell invade neighbor cells
If the cancer cells grow to its tumor size, they may also invade and kill their neighbor cells by producing abnormal or excessive signaling chemicals (hormones or cytokines) which upset the normal chemical balance of the body and alter the metabolic pathways, leading to disordered and violent cellular behavior.

1. Distance spread
There are many ways cancer causes of distant formation of secondary cancers1. Local spreading, lymph vessel, blood vessel
1.1. Local spreading as soon as the cancer cells grow to its tumor size, it will invade the nearby area. The reason of its action still unknown, but researchers suspect
a. As the tumor grows, it needs more space by pressing on the nearby normal body tissue nearby naturally for its own survival.
b. Enzyme
Tumors contain large amount of enzymes produced by the cancerous cells to ensure their survival by breaking down the nearby tissues, making a pathway for itself to invade the healthy tissue. Scientists have discovered a substance made by cancer cells which plays a big part in the local spread of cancers.

1.2. Spread through lymph vessel
If some cancer cells detached from the primary tumor and travel can grow into a secondary cancer but most of time they are trapped in the nearby lymph nodes closest to the original tumor.

1.3. Spread through blood circulation
Similar to spread through lymph vessel, cancer cells detached from origanl tumor can enter the blood stream by slipping pass the blood vessel wall and start grow into the secondary tumor as they are trapped into some small capillaries.
It may sound horrible, but only one out of thousands survive this journal to form a secondary cancer or metastasis.

2. Travel of clumps of cancer along the channels
Out of the above, sometimes, cancer cells detached from the primary tumor can travel through other channels, but they do not spread randomly, because some parts of the body are more vulnerable to becoming metastatic sites than others.

3. Arrival of cancer cells at a distance site
The development of the survival of cancer cells get trapped and grow into second tumor is obvious, but researchers do not know how it can get out of the trapping area to invade other organs of the body.

4. Angiogenesis
Angiogenesis is defined as a process involving the growth of new blood vessels from pre-existing vessels. As they arrived in area distancing from the primary tumor. The secondary tumor can persuade the adjacent tissue to build blood vessels by providing it with vital nutrients and oxygen, because they are not also recognized by immune system as some foreign substances.

5. Etc.

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