Dietary Minerals Boron: The effects of Dietary boron on 2-aminoethoxydiphenyl borate (2-APB) and ORAI1

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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                                 Dietary Minerals 

Dietary Minerals are the group of minerals which is essential for our body to sustain normal functions and physical health.

                                      Boron

Boron, a vital trace mineral found abundantly in Almond, Red Apple, Apricots, Avocado, Banana, Red kidneyBeans, etc., is necessary for the normal growth and health of the body. Boric acid has antiseptic and antiviral activity. Its aqueous solutions have been used as mouth-washes, eye-drops, skin lotions and cosmetics(1).

      The effects of Dietary boron on 2-aminoethoxydiphenyl borate (2-APB) and ORAI1



In the study to assess the influence of Orai1(ORAI calcium release-activated calcium modulator 1) intervention on mouse airway epithelium reactions in vivo and in vitro, found that administration of 2-aminoethoxydiphenyl borate (2-APB) into the nostrils suppressed Orai1 expression in nasal and tracheal mucosa of treated mice compared with that in control mice and restrained the mediators in nasal lavage fluid, bronchoalveolar lavage fluid, and airway mucosa of treated groups compared with those in control groups. Similarly, the 2-APB intervention also alleviated Orai1 and the production of the mediators in culture supernatant and cultured airway epithelium under allergic conditions(10).

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Sources
(1) http://chemicalland21.com/industrialchem/inorganic/BORIC%20ACID.htm
(10) http://www.ncbi.nlm.nih.gov/pubmed/22289729