Wednesday, August 31, 2016

Most Common Diseases of Ages of 50 Plus: Prostate Cancer - The Causes and risk factors

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Among elderly men, cancer of the prostate (451 per 100,000), the lung (449 per 100,000) and the colon (176 per 100,000) make up around half of all diagnosed cancers. Prostate cancer is around 22 times more frequent among elderly men than among younger men. The corresponding most frequent cancers among elderly women, making up 48% of all malignant cancers, are breast (248 per 100,000), colon (133 per 100,000), lung (118 per 100,000) and stomach cancer (75 per 100,000), According to the Danish Cancer Society, Institute of Cancer Epidemiology(PubMed)

Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

                             Prostate Cancer

Prostate warped around the around a tube (the urethra) is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of semen that carries sperm.

Prostate cancer is defined as a condition in which the cells of prostate has become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

                 Causes and risk factors

1. Age
The risk of developing prostate cancer increases with age of over 45

2. Family history
Statistic showed that if one of your directed family member has prostate cancer, your are twice at risk to develop it as well.

3. Race
Prostate cancer are more likely to strike black and white or Hispanic men in the US.

4. Heredity
Certain genes mutation are associated in promoting the growth of prostate cancer, including Hereditary Prostate cancer gene 1 (HPC1), transmembrane protease, serine 2-ERG or Transmembrane protease, serine 2-ETV1/4, etc.
Researcher found that up to 70 percent of men with prostate cancer have lost one copy of the Phosphatase and tensin homolog (PTEN) gene at the time of diagnosis. The tumor protein 53
(p53) mutations are late event in pathology of prostate cancer.

5. Low levels of vitamin D in blood

Researcher found that men with deficiency of level of vitamin D in the blood are at higher risk to develop prostate cancer.

6. Excessive drinking
Excessive drink not only increases the risk of liver cancer but also associated with higher risk of prostate cancer as it interfere with folate metabolism. Risk of prostate cancer is much high for men with excessive drinking habit and folate deficiency.

7. Enlarged prostate
Men with enlarged prostate are at high risk in developing prostate cancer.

8. Sexual transmitting diseases
Infected diseases such as chlamydia, gonorrhea, or syphilis are associated with higher risk of the diseases.

9. Obesity
In a study of Obesity May Raise Risk of Prostate Cancer Spread, Christopher J. Keto, MD, a urological oncology postdoctoral associate at Duke University Medical Center, Durham, N.C. found that overweight men were three times more likely to have their cancer spread.
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