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Wednesday, September 14, 2016

Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Nan Jiang (Rhizome Languas galangae)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                 
          Nan Jiang (Rhizome Languas galangae)


Nan Jiang is also known as Ireater galangal. The acrid and warm herb has been used in TCM as anti fungal and anti cancer agent and to treat inflammation of the mucus, flatulence of the digestive tract, bad digestion, bad circulation with cold and/or numb limbs, allergy (nose). flu with cough, chronic cough, pain in the stomach etc., by enhancing the functions of stomach and lung channels.

Ingredients
1. Kaempferol
2. Galangin
3. Galangol
4. Pinene
5. Eugenol
6. L’-acetoxychavicol acetate
7. Etc.

Health Benefits
1. Neuroprotective effect
In the study to investigation the cognitive improvement of Alpinia galanga (AG) fractions in Alzheimer’s type of amnesia in mice induced by Aβ((25-35)), showed that Anti-amnesic effect was exerted by various fractions of Alpinia galanga. Among all fractions, preeminent neuroprotection was exerted by chloroform fraction, which has compound, 1′δ-1′-acetoxyeugenol acetate and it may be a potential therapeutic agent for Alzheimer’s type of amnesia. These results further motivate us to explore the activity of lead compound’s anti-amnesic effect on transgenic mice model of AD(1).

2. Anti-Streptococcus mutans efficacy
In the study to test in vitro anti-Streptococcus mutans activity of Thai herbal formulas used against dental caries (THF-DC), indicated that Subsequent determination of their MIC revealed that the formula containing Albizia myriophylla Benth. (Leguminosae), Alpinia galanga (L.) Willd. (Zingiberaceae), Avicennia marina (Forssk.) Vierh. (Acanthaceae), and Ocimum sanctum L. (Lamiaceae) was the most active, with MIC at 250 µg/mL(2).

3. Neurotransmitter Metabolic Enzymes and Antioxidants
In the assessment to investigate the effect of an ethanol extract of Alpinia galanga (L.) Willd (EAG) on oxidative stress induced Alzheimer’s type amnesia in mice, found that Mice were treated with an experimental extract at 200 mg/kg and 400 mg/kg dose for 14 days and injected with neurotoxic Aβ and the doses were continued for 21 days. Behavioural studies with open field, step-down inhibitory avoidance and a water maze after treatment indicated the acceleration in cognitive function. The elevated levels of acetylcholinesterase and monoamine oxidase enzymes in amnesia induced mice were attenuated by treatment with EAG. The generation of free radicals was decreased due increased activity of antioxidant enzymes after treatment with EAG(3).

4. Antileishmanial activity
Hexane, chloroform and ethyl acetate extracts (100 microg/ml) of Alpinia galanga rhizomes exhibited significant activity in vitro against promastigotes of L. donovani (4).

5. Immunostimulating activity
In the study to test the Hot water polysaccharide extracts of Anacyclus pyrethrum (L.) Link. (family Compositae) Citrullus colocynthis (L.) Schrad. (family Cucurbitaceae) and Alpinia galanga (L.) Willd. (family Zingiberaceae) for their immunostimulating activity in mice, indicated that The fractions from Anacyclus pyrethrum and Alpinia galanga showed a marked stimulating effect on the reticulo-endothelial system (RES) and increased the number of peritoneal exudate cells (PEC), and spleen cells of mice. In this case, the optimum doses were 50 and 25 mg/kg for the two fractions, respectively. On the other hand, the polysaccharide extracts of both Anacyclus pyrethrum and Alpinia galanga markedly enhanced the proliferation of the murine spleen cells in vitro using two tests (in vitro and in vivo effect)(5).

6. Etc.

Side Effects
1. No side effect is known.


Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/21911048
(2) http://www.ncbi.nlm.nih.gov/pubmed/22489572
(3) http://www.ncbi.nlm.nih.gov/pubmed/21280111
(4) http://www.ncbi.nlm.nih.gov/pubmed/21046987
(5) http://www.ncbi.nlm.nih.gov/pubmed/12963136


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